| Evaluation of Efficacy of Trifluridine/Tipiracil Plus an Anti-IL-1α True Human Antibody Versus Trifluridine/Tipiracil Plus Placebo in Metastatic Colorectal Cancer Patients After Failure of Oxaliplatin, Irinotecan, Fluoropyrimidine (NCT05201352) | Centre Georges Francois Leclerc | 2022-10-13 |
| Application of 18F-PSMA PET / CT Imaging in Prostate Specific Membrane Antigen Positive Tumor (NCT05761366) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2022-10-13 |
| Topical Ruxolitinib 1.5% for Hidradenitis Suppurativa Treatment (NCT04414514) | Milton S. Hershey Medical Center | 2022-10-13 |
| First-line Treatment With Dacomitinib Plus Anlotinib for Patients With Advanced NSCLC With EGFR 21L858R Mutations (NCT05271916) | Shanghai Chest Hospital | 2022-10-13 |
| Neoadjuvant and Adjuvant Toripalimab and Cetuximab in Patients With Recurrent, Resectable Squamous Cell Carcinoma of Head and Neck: a Prospective, Single-arm,Phase II Study (NCT05586100) | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 2022-10-13 |
| Efficacy and Safety of AC102 Compared to Steroids in Adults With Idiopathic Sudden Sensorineural Hearing Loss (ISSNHL) (NCT05776459) | AudioCure Pharma GmbH | 2022-10-13 |
| A Dose Finding Study of VN-0200 (NCT05547087) | Daiichi Sankyo | 2022-10-13 |
| Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis (NCT05185947) | National Cancer Institute (NCI) | 2022-10-13 |
| Repeated Intranasal Esketamine Plus Almond Therapy in Patients With Treatment Resistant Depression (NCT05323019) | Zylorion Health | 2022-10-13 |
| A Study of Vatiquinone for the Treatment of Participants With Friedreich Ataxia (NCT05485987) | PTC Therapeutics | 2022-10-12 |
| Study of Trilaciclib and Lurbinectidin (NCT05578326) | UNC Lineberger Comprehensive Cancer Center | 2022-10-12 |
| Study of Oral MRT-2359 in Selected Cancer Patients (NCT05546268) | Monte Rosa Therapeutics, Inc | 2022-10-12 |
| A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy. (NCT05523167) | argenx | 2022-10-12 |
| A Study of Remimazolam Tosilate for Sedation in the ICU (NCT05152303) | Fujian Shengdi Pharmaceutical Co., Ltd. | 2022-10-12 |
| Study of Denosumab for Prevention of Skeletal Disease Progression in Children With Fibrous Dysplasia (NCT05419050) | National Institute of Dental and Craniofacial Research (NIDCR) | 2022-10-12 |
| Phase 2 Shigella Vaccine and Challenge (NCT04242264) | National Institute of Allergy and Infectious Diseases (NIAID) | 2022-10-12 |
| Study to Evaluate D-1553 in Combination With IN10018 in Subjects With Solid Tumors (NCT05379946) | InventisBio Co., Ltd | 2022-10-12 |
| A Study to Evaluate AB-1001 Striatal Administration in Adults With Early Manifest Huntington's Disease (NCT05541627) | AskBio France, SAS, a subsidiary of AskBio Inc. | 2022-10-12 |
| a Study to Evaluate the Safety and Efficacy of D-1553 Combined With IN10018 in KRAS G12C Mutant Solid Tumors (NCT06166836) | InxMed (Shanghai) Co., Ltd. | 2022-10-12 |
| TACE Combined With Penpulimab and Anlotinib for Advanced HCC (NCT05344924) | Zhongda Hospital | 2022-10-12 |
| The Safety of Non-vitamin K Oral Anticoagulants Compared to Warfarin Early After Cardiac Surgery (NCT05006287) | St. Paul's Hospital, Canada | 2022-10-12 |
| Study of Efficacy, Safety and Tolerability of Remibrutinib in Adult Participants With an Allergy to Peanuts (NCT05432388) | Novartis Pharmaceuticals | 2022-10-12 |
| Deescalation of Endocrine Therapy Duration in Women With HR+ HER2- Breast Cancer at Very Low Risk (NCT05297617) | UNICANCER | 2022-10-12 |
| Selinexor, Pomalidomide, and Dexamethasone For Multiple Myeloma With CNS Involvement (NCT05478993) | Peking University People's Hospital | 2022-10-12 |
| Efficacy and Safety of COMP360 Psilocybin Therapy in Anorexia Nervosa: a Proof-of-concept Study (NCT05481736) | COMPASS Pathways | 2022-10-12 |
| Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CIC (NCT05491525) | Urovant Sciences GmbH | 2022-10-12 |
| Glucagon-Like Peptide-1 Receptor Agonist in the Treatment of Adult, Obesity-related, Symptomatic Asthma (GATA-3) (NCT05254314) | Vanderbilt University Medical Center | 2022-10-11 |
| Clinical Trial on Agitation in Alzheimer's Dementia (NCT05543681) | IGC Pharma, LLC | 2022-10-11 |
| A Clinical Trial of Interventions to Support Family Surrogates of Critically Ill Patients (NCT05587517) | Weill Medical College of Cornell University | 2022-10-11 |
| Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma (NCT05524935) | H. Lee Moffitt Cancer Center and Research Institute | 2022-10-11 |
| An Innovative Chinese Herbal Formula for the Treatment of Gout (NCT05499312) | Chinese University of Hong Kong | 2022-10-11 |
| A Study to Assess the Changes in Pigmentation and Safety of Afamelanotide in Patients With Vitiligo on the Face (NCT05210582) | Clinuvel, Inc. | 2022-10-11 |
| Therapeutic Evaluation of Low-dose IL-2-based Immunomodulatory Approach in Patients With Early AD (NCT05468073) | Centre Hospitalier St Anne | 2022-10-11 |
| A Phase I/II Study of WJ13404 Monotherapy in Patients With Advanced or Mentastatic Non-Small Cell Lung Cancer (NCT05662670) | Suzhou Junjing BioSciences Co., Ltd. | 2022-10-11 |
| Study Designed to Evaluate the Effect of CimetrA in Patients Diagnosed With COVID-19 (NCT05037162) | MGC Pharmaceuticals d.o.o | 2022-10-11 |
| A Study Exploring Efficacy of Peginterferon in Patients With Herpes Zoster (NCT05492591) | Shanghai Institute Of Biological Products | 2022-10-11 |
| Angiotensin-Neprilysin Inhibition in Hemodialysis Initiation (NCT05498181) | Brigham and Women's Hospital | 2022-10-11 |
| Tecovirimat for Treatment of Monkeypox Virus (NCT05559099) | National Institute of Allergy and Infectious Diseases (NIAID) | 2022-10-10 |
| The Role of Dexmedetomidine as Myocardial Protector in Pediatric Cardiac Surgery Total Correction of Tetralogy of Fallot (NCT05579964) | National Cardiovascular Center Harapan Kita Hospital Indonesia | 2022-10-10 |
| A Study to Assess an ATX Inhibitor (IOA-289) in Patients With Metastatic Pancreatic Cancer (NCT05586516) | iOnctura | 2022-10-10 |
| Perioperative Analgesia Modes in Minimally Invasive Esophagectomy (NCT05504265) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2022-10-10 |
| Mitoxantrone Hydrochloride Liposome Combined With Rituximab and Lenalidomide (M+R2) in Patients With Relapsed and Refractory Diffuse Large B-Cell Lymphoma (NCT05575973) | Jianfeng Zhou | 2022-10-10 |
| A Study of Toripalimab in Adjuvant Therapy After Resection of High-risk Renal Cancer (NCT06584435) | Tianjin Medical University Second Hospital | 2022-10-10 |
| Characterization of the Temporo-masseteric Nerve Block (TMNB) in Healthy Subjects (NCT05507164) | Rutgers, The State University of New Jersey | 2022-10-10 |
| Evaluation of the Building Healthy Life Skills Program (NCT05611060) | University of California, Merced | 2022-10-10 |
| Biomarker and Edema Attenuation in IntraCerebral Hemorrhage (BEACH) (NCT05020535) | Johns Hopkins University | 2022-10-10 |
| Envofolimab and Lenvatinib Combined With Gemcitabine Plus Cisplatin for Advanced BTC as First-Line Treatment(ENLIGHTEN) (NCT05410197) | Sun Yat-sen University | 2022-10-10 |
| Pembrolizumab as First-line Treatment for Advanced NSCLC Complicated With COPD (NCT05578222) | Tianjin Chest Hospital | 2022-10-10 |
| Cadonilimab Plus Nab-Paclitaxel for Recurrent or Metastatic Muscle Invasive Bladder Cancer (NCT06009848) | Tianjin Medical University Second Hospital | 2022-10-10 |
| Hydroxychloroquine in Combination With Encorafenib and Cetuximab or Panitumumab in the Treatment of Metastatic BRAF-mutated Colorectal Cancer Refractory (NCT05576896) | Northwestern University | 2022-10-10 |
| Renal Mechanism of SGLT2 Inhibition (NCT05507892) | University of Colorado, Denver | 2022-10-10 |
| Pentoxifylline as Adjunctive Therapy in Patients With Ulcerative Colitis (NCT05558761) | Tanta University | 2022-10-10 |
| A Study of Fisetin to Treat Carpal Tunnel Syndrome (NCT05416515) | Peter C. Amadio, M.D. | 2022-10-09 |
| Induction Chemoimmunotherapy in Combination With Chemoradiotherapy and Consolidation Immunotherapy in Unresectable Locally Advanced Non-Small Cell Lung Cancer (NCT07632365) | Shanghai Chest Hospital | 2022-10-09 |
| Olverembatinib Combined With Reduced-Intensity Chemotherapy and Venetoclax for de Novo Ph+ ALL (NCT05594784) | Institute of Hematology & Blood Diseases Hospital, China | 2022-10-08 |
| Efficacy and Safety Study of SHR-1819 Injection in Adult Patients With Severe Atopic Dermatitis (NCT05549947) | Shanghai Hengrui Pharmaceutical Co., Ltd. | 2022-10-08 |
| Effects of Intravenous Lidocaine on ED50, ED95 and NTI Values of Propofol Induced Unconsciousness (NCT05573191) | General Hospital of Ningxia Medical University | 2022-10-08 |
| Targeted or Chemotherapy Combined With Immunotherapy Versus Chemotherapy for PD-1 Inhibitor Refractory R/M NPC (NCT05549466) | Sun Yat-sen University | 2022-10-08 |
| Effects of Semaglutide on Nicotine Intake (NCT05530577) | University of North Carolina, Chapel Hill | 2022-10-07 |
| Pembrolizumab and Lenvatinib in Advanced Cervical Cancer (NCT04865887) | Georgetown University | 2022-10-07 |
| Bortezomib and Pembrolizumab With or Without Pelareorep for the Treatment of Relapsed or Refractory Multiple Myeloma, AMBUSH Trial (NCT05514990) | University of Southern California | 2022-10-07 |
| A Study of CM310 in Children Patients With Moderate-to-severe Atopic Dermatis (NCT05579925) | Keymed Biosciences Co.Ltd | 2022-10-07 |
| Testing the Addition of Radiation Therapy to the Usual Treatment (Immunotherapy With or Without Chemotherapy) for Advanced Stage Non-small Cell Lung Cancer Patients Who Are PD-L1 Negative (NCT04929041) | National Cancer Institute (NCI) | 2022-10-07 |
| Evaluating Endometriosis With 16α-(18)F-fluoro-17β-estradiol ([F-18] FES) PET/MRI (NCT04347135) | Annie (Annie) T. Packard | 2022-10-07 |
| MDMA-assisted Therapy for Adjustment Disorder (AD) in Dyads of Patients With Cancer and a Concerned Significant Other (NCT05584826) | Sunstone Medical | 2022-10-06 |
| A Study to Evaluate the Efficacy and Safety of HR19042 Capsules in the Treatment of Autoimmune Hepatitis. (NCT05476900) | Jiangsu HengRui Medicine Co., Ltd. | 2022-10-06 |
| Study to Evaluate EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sclerosing Cholangitis (NCT05525520) | Escient Pharmaceuticals, Inc | 2022-10-06 |
| A Study of Radiation Therapy and Cemiplimab for People With Skin Cancer (NCT05574101) | Memorial Sloan Kettering Cancer Center | 2022-10-06 |
| Adrecizumab (HAM8101) to Improve Prognosis and Outcomes in COVID-19 Trial (NCT05156671) | Universitätsklinikum Hamburg-Eppendorf | 2022-10-06 |
| A Study of Brief Behavioral Activation for the Treatment of Depression in Older Adult Cancer Survivors (NCT05574127) | Memorial Sloan Kettering Cancer Center | 2022-10-06 |
| A Study to Assess Safety, Efficacy, and Pharmacokinetics of INM004 in Pediatric Patients With STEC-HUS (NCT05569746) | Inmunova S.A. | 2022-10-06 |
| Cord Blood Transplant With Dilanubicel for the Treatment of HIV Positive Hematologic Cancers (NCT04083170) | Fred Hutchinson Cancer Center | 2022-10-06 |
| A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid Tumors (NCT05572684) | NextCure, Inc. | 2022-10-06 |
| Zibotentan and Dapagliflozin in Patients With Type 2 Diabetes and Elevated Albuminuria (NCT05570305) | University Medical Center Groningen | 2022-10-06 |
| Dexmedetomidine Versus Propofol Sedation for Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea (NCT05303987) | Erin Kirkham | 2022-10-05 |
| A Study to Evaluate the Pharmacodynamics, Pharmacokinetics, Safety, and Efficacy of UB-221 IV Infusion as an add-on Therapy in Patients With Chronic Spontaneous Urticaria (NCT05298215) | United BioPharma | 2022-10-05 |
| METIMMOX-2: Metastatic pMMR/MSS Colorectal Cancer - Shaping Anti-Tumor Immunity by Oxaliplatin (NCT05504252) | University Hospital, Akershus | 2022-10-05 |
| Ponatinib Plus Chemotherapy in Acute Lymphoblastic Leukemia Patients (NCT05306301) | Gruppo Italiano Malattie EMatologiche dell'Adulto | 2022-10-05 |
| A Phase II Study of the Combination of Azacitidine and Pembrolizumab for Patients Relapsed/Refractory Hodgkin's Lymphoma (NCT05355051) | M.D. Anderson Cancer Center | 2022-10-05 |
| Investigating RELEARN Neurofeedback as Treatment for Chronic Musculoskeletal Pain (NCT05335486) | Redo-Neurosystems | 2022-10-05 |
| [68Ga]Ga-PentixaFor PET Imaging in CNS Lymphoma Patients (NCT05222269) | Pentixapharm AG | 2022-10-05 |
| Efficacy of Esmolol Versus Magnesium Sulphate on Quality of Recovery in Patients Undergoing Laparoscopic Cholecystectomy: Randomized Controlled Study (NCT05850832) | Alexandria University | 2022-10-05 |
| A Double-blind Study to Evaluate the Safety of Glutamic Acid Decarboxylase Gene Transfer in Parkinson's Participants (NCT05603312) | MeiraGTx, LLC | 2022-10-05 |
| GV1001 Subcutaneous(SC) for the Treatment of Mild to Moderate Alzheimer's Disease (AD) (NCT05189210) | GemVax & Kael | 2022-10-05 |
| Safety and Immunogenicity of SCB-2019 in Children <18 Years of Age (NCT05193279) | Clover Biopharmaceuticals AUS Pty | 2022-10-05 |
| RNS System LGS Feasibility Study (NCT05339126) | NeuroPace | 2022-10-04 |
| Efficacy, Safety, Tolerability, and Pharmacokinetics of NBI-1117568 in Adults With Schizophrenia (NCT05545111) | Neurocrine Biosciences | 2022-10-04 |
| Olaparib in Unresectable/Metastatic Melanoma With BRCA1/2 (NCT05482074) | Dana-Farber Cancer Institute | 2022-10-04 |
| A Study to Evaluate Safety, Tolerability, and Preliminary Effect of the GEN1053 Antibody on Malignant Solid Tumors as Monotherapy (NCT05435339) | Genmab | 2022-10-04 |
| Initial Safety Study of the TRUE AVC in Hemodialysis Access (TRUE AVC I Study) (NCT05567757) | Vascudyne, Inc. | 2022-10-04 |
| A Study of BMS-986442 With Nivolumab With or Without Chemotherapy in Solid Tumors and Non-small Cell Lung Cancer (NCT05543629) | Bristol-Myers Squibb | 2022-10-04 |
| Clinical Research Study to Learn About the Effect and Safety of Different Doses of FE 999302 When Given as a Single Dose for Final Development of the Eggs After Ovarian Stimulation (NCT05571111) | Ferring Pharmaceuticals | 2022-10-04 |
| Efficacy Biomarkers of DAOIB for Dementia (NCT05582161) | Chang Gung Memorial Hospital | 2022-10-03 |
| Study To Investigate the Efficacy and Safety of Sitravatinib in Combination With Tislelizumab in Participants With Esophageal Squamous Cell Carcinoma (NCT05461794) | BeiGene | 2022-10-03 |
| Phase 2a, 28-day Investigational Use Study of ARINA-1 in Non-Cystic Fibrosis Bronchiectasis (NCFBE) With Excess Mucus and Cough (NCT05495243) | Renovion, Inc. | 2022-10-03 |
| Lu-177-DOTATATE (Lutathera) in Combination With Olaparib in Inoperable Gastroenteropancreatico Neuroendocrine Tumors (GEP-NET) (NCT04086485) | National Cancer Institute (NCI) | 2022-10-03 |
| A Clinical Trial of Regorafenib in Patients With Pretreated Advanced Melanoma (NCT05370807) | Universitair Ziekenhuis Brussel | 2022-10-03 |
| Investigating the Therapeutic Effects of Psilocybin in Treatment-Resistant Post-Traumatic Stress Disorder (NCT05243329) | Halucenex Life Sciences Inc. | 2022-10-03 |
| A Phase 1b/2 Trial of the Safety and Microbiological Activity of Bacteriophage Therapy in Cystic Fibrosis Subjects Colonized With Pseudomonas Aeruginosa (NCT05453578) | National Institute of Allergy and Infectious Diseases (NIAID) | 2022-10-03 |
| Radiation/Temozolomide and Immunotherapy With Daratumumab to Improve Antitumor Efficacy in Glioblastoma (NCT04922723) | West Virginia University | 2022-10-03 |