| A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Cutaneous Lichen Planus (NCT05593432) | Incyte Corporation | 2022-11-23 |
| Fluzoparib in Combination With or Without Camrelizumab for Homologous Recombinant Deficiency (HRD) HER2 Negative Advanced Breast Cancer (NCT05656131) | wang shusen | 2022-11-23 |
| A Study of RC48-ADC Combined with JS001 for Postoperative Adjuvant Treatment of Upper Tract Urothelial Carcinoma (NCT05917158) | Jinling Hospital, China | 2022-11-23 |
| Venetoclax in Patients With MDS or AML in Relapse After AHSCT (NCT05226455) | Groupe Francophone des Myelodysplasies | 2022-11-23 |
| A Study to Evaluate the Efficacy, Safety, and Immunogenicity of SARS-CoV-2 Variant (BA.4 /5) mRNA Vaccine (NCT05636319) | Suzhou Abogen Biosciences Co., Ltd. | 2022-11-23 |
| Methotrexate as Remission Maintenance Therapy After Remission-Induction With Tocilizumab and Glucocorticoids in Giant Cell Arteritis (NCT05623592) | University of Bonn | 2022-11-23 |
| A Study of SHR-1501 Alone or in Combination With BCG or SHR-1316 in Subjects With NMIBC (NCT05410730) | Shanghai Hengrui Pharmaceutical Co., Ltd. | 2022-11-23 |
| Safety and Immunogenicity of a Chimeric Recombinant Covid19 Vaccine SpiN-Tec MCTI UFMG (NCT07134725) | Federal University of Minas Gerais | 2022-11-23 |
| [68Ga]Ga-ABY-025 PET for Quantification of HER2-status in Solid Tumors (NCT05619016) | Karolinska University Hospital | 2022-11-23 |
| Safety and Tolerability Study of QLS-101 in Adolescents With Sturge-Weber Syndrome (SWS)-Related Glaucoma Due to Elevated Episcleral Venous Pressure (EVP) (NCT05495269) | Qlaris Bio, Inc. | 2022-11-23 |
| Adding Itacitinib to Cyclophosphamide and Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Hematopoietic Stem Cell Transplants (NCT05364762) | City of Hope Medical Center | 2022-11-23 |
| Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations (NCT05544552) | Tyra Biosciences, Inc | 2022-11-22 |
| Safety and Effect of Oral RVX000222 in Subjects With Fabry Disease (NCT03228940) | Resverlogix Corp | 2022-11-22 |
| A Study of Topical Pirenzepine or Placebo in Oncology Patients With Chemotherapy Induced Peripheral Neuropathy (NCT05488873) | WinSanTor, Inc | 2022-11-22 |
| A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 In Participants With Osteoarthritis Pain (NCT05620563) | Eli Lilly and Company | 2022-11-22 |
| Smell in COVID-19 and Efficacy of Nasal Theophylline (SCENT 3) (NCT05947643) | Washington University School of Medicine | 2022-11-22 |
| Rituximab Plus Venetoclax in Combination With Zandelisib in Subjects With CLL (NCT05209308) | MEI Pharma, Inc. | 2022-11-22 |
| A Randomized, Double Masked, Parallel Group, Dose-finding Study to Evaluate SYL1801 in Patients With Neovascular Age-related Macular Degeneration (AMD) (NCT05637255) | Sylentis, S.A. | 2022-11-22 |
| Pharmacokinetics and Safety of TIN816 in Patients With Sepsis-associated Acute Kidney Injury (NCT05507437) | Novartis Pharmaceuticals | 2022-11-22 |
| Clinical Trial to Investigate the Safety and Tolerability of EP395 in Patients With COPD (NCT05572333) | EpiEndo Pharmaceuticals | 2022-11-22 |
| Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation (NCT05609578) | Mirati Therapeutics Inc. | 2022-11-22 |
| A Study Using Subject-specific MRD to Adopt Treatment After HSCT for Subjects With MDS (NCT05788679) | Karolinska University Hospital | 2022-11-22 |
| Treatment of Striae Distensae With Fractional Radiofrequency and Topical Tretinoin (NCT05461755) | Merete Haedersdal | 2022-11-22 |
| Immunotherapy With or Without Radiation Therapy for Metastatic Urothelial Cancer (NCT04936230) | National Cancer Institute (NCI) | 2022-11-22 |
| N-DOSE AD: A Dose Optimization Trial of Nicotinamide Riboside in Alzheimer's Disease (NCT05617508) | Haukeland University Hospital | 2022-11-22 |
| Study to Evaluate the Effects of Cenicriviroc Mesylate on Arterial Inflammation in People Living With HIV (NCT04334915) | National Institute of Allergy and Infectious Diseases (NIAID) | 2022-11-22 |
| Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease (NCT05548452) | Virginia Commonwealth University | 2022-11-21 |
| A Study to Assess Disease Activity of Intravenously (IV) Infused Telisotuzumab Vedotin in Adult Participants With Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (NCT05513703) | AbbVie | 2022-11-21 |
| Testing Interruption of Hormonal Medications in Patients Responding Exceptionally to Therapy for Metastatic Prostate Cancer, (A-DREAM) (NCT05241860) | Alliance for Clinical Trials in Oncology | 2022-11-21 |
| An Intravenous (IV) Zanamivir Pharmacokinetics (PK) Study in Hospitalized Neonates and Infants With Influenza Infection (NCT04494412) | GlaxoSmithKline | 2022-11-21 |
| Psoriatic Arthritis Study of Izokibep (NCT05623345) | ACELYRIN Inc. | 2022-11-21 |
| A Study to Evaluate MORF-057 in Adults With Moderately to Severely Active UC (NCT05611671) | Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company) | 2022-11-21 |
| Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer (NCT05474846) | M.D. Anderson Cancer Center | 2022-11-21 |
| Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors (NCT05278208) | Nationwide Children's Hospital | 2022-11-21 |
| CLI and FAR for Intraoperative Margin Assessment (NCT05496101) | King's College London | 2022-11-21 |
| Study of the Efficacy and Safety of Ponsegromab in Patients With Cancer, Cachexia and Elevated GDF-15 (NCT05546476) | Pfizer | 2022-11-21 |
| Pyronaridine in Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML) (NCT05291390) | Armaceutica, Inc. | 2022-11-21 |
| A Head-to-head Comparison of [68Ga]Ga-FAPI and [68Ga]Ga-TATE PET/CT in Patients With Nasopharyngeal Carcinoma: a Single-center, Prospective Study (NCT05990998) | First Affiliated Hospital of Fujian Medical University | 2022-11-20 |
| A Prospective, Open Label, Dose-escalation, SAD/MAD, Multicenter, 24weeks, Phase I/IIa Clinical Trial to Evaluate the Safety, Tolerability and Pharmacodynamics of Investigational Product (VM-001) in Patients With Graft-versus-host Disease(GvHD) (NCT05276076) | ViGenCell Inc. | 2022-11-20 |
| Treatment of Renal Colic in the Emergency Department: Comparison Between Magnesium Sulfate and Lidocaine. (NCT05653401) | University of Monastir | 2022-11-20 |
| A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Lichen Sclerosus (NCT05593445) | Incyte Corporation | 2022-11-18 |
| The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation (NCT05436418) | National Cancer Institute (NCI) | 2022-11-18 |
| Feasibility of Study of Empagliflozin in Patients With Autosomal Dominant Polycystic Kidney Disease (NCT05510115) | University of Colorado, Denver | 2022-11-18 |
| A Study of WX390 Combined With Toripalimab in Patients With Advanced Solid Tumors (NCT06117566) | Shanghai Jiatan Pharmatech Co., Ltd | 2022-11-18 |
| Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration (NCT05380492) | Perceive Biotherapeutics, Inc. | 2022-11-17 |
| STEMVAC in Patients With Early Stage Triple Negative Breast Cancer (NCT05455658) | University of Washington | 2022-11-17 |
| A Study to Evaluate Administration of SBT101 Gene Therapy in Adult Patients With Adrenomyeloneuropathy (AMN) (NCT05394064) | SwanBio Therapeutics, Inc. | 2022-11-17 |
| Probiotic Blend for Celiac Disease (NCT05646823) | Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude | 2022-11-17 |
| Pectoral Nerve Blocks (PECs) for Cardiovascular Implantable Electronic Device Placement (NCT05283980) | Beth Israel Deaconess Medical Center | 2022-11-17 |
| Study of a Respiratory Syncytial Virus Candidate Encapsulated in a Lipid Nanoparticle Based Formulation in Adults Aged 18 to 50 Years and 60 Years and Older (NCT05639894) | Sanofi Pasteur, a Sanofi Company | 2022-11-17 |
| Study Evaluating Zenocutuzumab in Patients With or Without Molecularly Defined Cancers (NCT05588609) | Partner Therapeutics, Inc. | 2022-11-17 |
| Opium Tincture Against Chronic Diarrhea - Patients (NCT05690321) | Asbjørn Mohr Drewes | 2022-11-17 |
| Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors (NCT05286801) | National Cancer Institute (NCI) | 2022-11-17 |
| VTX958 Versus Placebo for the Treatment of Moderate to Severe Psoriasis (NCT05655299) | Ventyx Biosciences, Inc | 2022-11-17 |
| Use of a Novel SUBCUTaneous Preparation of Furosemide to Facilitate Early Supported Discharge of Patients With Heart Failure (NCT05419115) | NHS Greater Glasgow and Clyde | 2022-11-17 |
| Clinical Study of VG161 Combined With Nivolumab Injection in Patients With Advanced Metastatic Gastric Cancer (NCT06008925) | CNBG-Virogin Biotech (Shanghai) Ltd. | 2022-11-17 |
| Efficacy of SN132D in Patients With Suspected Endometriosis (NCT05664828) | Spago Nanomedical AB | 2022-11-17 |
| Role of a CCK Receptor Antagonist Proglumide in Management of Chronic Pancreatitis (NCT05551858) | Georgetown University | 2022-11-17 |
| Pirtobrutinib (LOXO-305) Consolidation for MRD Eradication in Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL) Treated With Venetoclax (NCT05317936) | M.D. Anderson Cancer Center | 2022-11-16 |
| A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma (NCT05533775) | Hoffmann-La Roche | 2022-11-16 |
| A Study of TAK-341 in Treatment of Multiple System Atrophy (NCT05526391) | Takeda | 2022-11-16 |
| Safety and Efficacy of Bimagrumab and Semaglutide in Adults Who Are Overweight or Obese (NCT05616013) | Eli Lilly and Company | 2022-11-16 |
| Safety, Immunogenicity and Efficacy of GSK S. Aureus Candidate Vaccine (GSK3878858A) When Administered to Healthy Adults (Dose-escalation) and to Adults 18 to 64 Years of Age With a Recent S. Aureus Skin and Soft Tissue Infection (SSTI) (NCT04420221) | GlaxoSmithKline | 2022-11-16 |
| A Substudy of Investigational Agents in Programmed Cell Death-1/Ligand 1 (PD-1/L1) Refractory Locally Advanced or Metastatic Urothelial Carcinoma (mUC) (MK-3475-04A) (NCT05562830) | Merck Sharp & Dohme LLC | 2022-11-16 |
| All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma (NCT05345002) | Stephen Bagley, MD, MSCE | 2022-11-16 |
| MRI Guided Radiation Therapy for the Treatment of High Risk Prostate Cancer (NCT05676463) | Thomas Jefferson University | 2022-11-16 |
| Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors (NCT05053971) | National Cancer Institute (NCI) | 2022-11-16 |
| Savolitinib Combine With Durvalumab in EGFR Wild-type Locally Advanced or Metastatic NSCLC (NCT05374603) | AstraZeneca | 2022-11-15 |
| Dazucorilant in Patients With Amyotrophic Lateral Sclerosis (NCT05407324) | Corcept Therapeutics | 2022-11-15 |
| Study of DF9001 in Patients With Advanced Solid Tumors (NCT05597839) | Dragonfly Therapeutics | 2022-11-15 |
| Allopurinol Versus Atorvastatin to Prevent Complications of Liver Cirrhosis (NCT05511766) | Tanta University | 2022-11-15 |
| Study of ZGGS18 in Patients With Advanced Solid Tumors (NCT05584800) | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 2022-11-15 |
| Using a Contact Dermatitis Model With Biologic Medications to Study Skin Inflammation (NCT05535738) | Wei-Che Ko | 2022-11-15 |
| A Study of Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of KAN-101 in Celiac Disease (ACeD-it) (NCT05574010) | Kanyos Bio, Inc., a wholly-owned subsidiary of Anokion SA | 2022-11-15 |
| A Study of Etavopivat for the Treatment of Anemia in Patients With Myelodysplastic Syndromes (MDS) (NCT05568225) | Forma Therapeutics, Inc. | 2022-11-15 |
| Investigational Scan (68Ga-FAPI-46 PET/CT) for Imaging of Cancer-Associated Fibroblasts for Localized Pancreatic Ductal Adenocarcinoma (NCT05518903) | Mayo Clinic | 2022-11-15 |
| The Potential Cardioprotective Effect of Addition of Atorvastatin in Breast Cancer Patients (NCT07668076) | Damanhour University | 2022-11-15 |
| 68Ga PET/CT Imaging in Breast Cancer Patients (NCT05622227) | Peking Union Medical College Hospital | 2022-11-15 |
| A Study of ICP-192 in Patients With FGFR2-Rearranged Unresectable or Metastatic Intrahepatic Cholangiocarcinoma (NCT05678270) | Beijing InnoCare Pharma Tech Co., Ltd. | 2022-11-15 |
| Neoadjuvant Nivolumab, Docetaxel, Cisplatin Therapy Followed by Surgery and Radiation Therapy for Resectable High Grade Salivary Gland Carcinoma (NCT05727410) | Myung-Ju Ahn | 2022-11-15 |
| Ruxolitinib in Seborrheic Dermatitis (NCT05787860) | Icahn School of Medicine at Mount Sinai | 2022-11-15 |
| A Phase 1/2a Study Evaluating Allocetra-OTS as Monotherapy or in Combination With Anti-PD-1 Therapy for the Treatment of Advanced Solid Tumor Malignancy (NCT05581719) | Enlivex Therapeutics RDO Ltd. | 2022-11-15 |
| Dexmedetomidine Combined With Bupivacaine for Erector Spinae Plane Block (NCT05590234) | October 6 University | 2022-11-15 |
| Testosterone Replacement to Alleviate Pain in Postmenopausal Women (TRAPP Trial) (NCT04895306) | Brigham and Women's Hospital | 2022-11-15 |
| YH001 Plus Envafolimab With or Without Doxorubicin in Patients With Advanced or Metastatic Sarcoma (NCT05448820) | Tracon Pharmaceuticals Inc. | 2022-11-14 |
| A Study of Brepocitinib in Adults With Active Non-Infectious Non-Anterior Uveitis (NCT05523765) | Priovant Therapeutics, Inc. | 2022-11-14 |
| A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Diabetic Peripheral Neuropathic Pain (NP05). (NCT05620576) | Eli Lilly and Company | 2022-11-14 |
| A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue (NCT05634369) | Nationwide Children's Hospital | 2022-11-14 |
| Pulse Glucocorticoid Therapy in Patients With ST-Segment Elevation Myocardial Infarction (NCT05462730) | Thomas Engstrom | 2022-11-14 |
| Micronutrient Supplementation in Children With ASD (NCT05268744) | University of California, San Francisco | 2022-11-14 |
| Azithromycin Treatment of Hospitalized Children With Asthmatic Symptoms (NCT05028153) | Copenhagen Studies on Asthma in Childhood | 2022-11-14 |
| Study to Evaluate the Efficacy and Safety of K-877-ER and CSG452 in Participants With NASH With Liver Fibrosis (NCT05327127) | Kowa Research Institute, Inc. | 2022-11-14 |
| A Study of MORAb-202 in Participants With Previously Treated Metastatic Non-Small Cell Lung Cancer (NSCLC) Adenocarcinoma (AC) (NCT05577715) | Bristol-Myers Squibb | 2022-11-14 |
| Trial of Quercetin, Bromelain, Rye Flower Pollen & Papain on Reducing Severity of Radiation-Induced Prostatitis (NCT04252625) | University of Utah | 2022-11-14 |
| Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial (NCT05327010) | National Cancer Institute (NCI) | 2022-11-14 |
| Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-Line Treatment in Participants With PD-L1-Positive (CPS ≥ 1) Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (NCT05287113) | Incyte Biosciences International Sàrl | 2022-11-14 |
| The Anchor Study: Digitally Delivered Intervention for Reducing Problematic Substance Use (NCT04925570) | Woebot Health | 2022-11-14 |
| An Efficacy and Safety Study of Mitiperstat (AZD4831) (MPO Inhibitor) vs Placebo in the Treatment of Moderate to Severe COPD. (NCT05492877) | AstraZeneca | 2022-11-14 |
| Efficacy of Pentoxifylline as Add on Therapy in COVID19 Patients (NCT04433988) | Sadat City University | 2022-11-13 |
| Neurovascular Regulation During Exercise in Humans With Chronic Kidney Disease: Sympatholysis in CKD (NCT05928936) | Emory University | 2022-11-11 |