| Phase Ib/IIa Dose Escalation and Expansion Study of [²¹²Pb]Pb-ADVC001 in Metastatic Prostate Cancer (TheraPb - Phase I/II Study). (NCT05720130) | AdvanCell Pty Limited | 2023-03-15 |
| An Open-label Study of Povetacicept in Autoantibody-Associated Glomerular Diseases (NCT05732402) | Alpine Immune Sciences, Inc. | 2023-03-15 |
| A Multi-Centre, Randomised, Controlled, Masked Phase 2 Study of the Safety and Efficacy of KIO-101 Ophthalmic Solution, Versus Vehicle Control in the Treatment of Dry Eye Disease in Patients With Autoimmune Disease (NCT05629364) | Kiora Pharmaceuticals, Inc. | 2023-03-15 |
| Quintuple Method for Treatment of Multiple Refractory Colorectal Liver Metastases (NCT05774964) | Liaoning Cancer Hospital & Institute | 2023-03-15 |
| Milciclib in Combination With Gemcitabine in Advanced NSCLC (NCT05651269) | Tiziana Life Sciences LTD | 2023-03-15 |
| Study of Polymeric Micellar Paclitaxel, Platinum Combined With Sindilizumab Injection for Advanced Non-squamous NSCLC (NCT05782426) | Jiangsu Cancer Institute & Hospital | 2023-03-15 |
| Safety and Tolerability of JSKN003 in Chinese Subjects With Advanced Solid Tumors (NCT05744427) | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | 2023-03-15 |
| A Study to Evaluate AZD2693 in Participants Who Are Carriers of the PNPLA3 148M Risk Allele With Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis (NCT05809934) | AstraZeneca | 2023-03-15 |
| The BLAST- 1 Trial - Cephalexin+Amoxicillin-clavulanate for Tuberculosis (NCT05664568) | Western Sydney Local Health District | 2023-03-15 |
| A Study of Treatment of Inflammation Before Stem Cell Transplant in People With a Primary Immune Regulatory Disorder (PIRD) and/or an Autoinflammatory Condition (NCT05787574) | Joseph Oved | 2023-03-15 |
| Induction Lorlatinib in Stage III Non-small Cell Lung Cancer (NCT05740943) | Guangdong Provincial People's Hospital | 2023-03-15 |
| A Study of Avutometinib (VS-6766) and Defactinib in People With Mesonephric Gynecologic Cancer (NCT05787561) | Memorial Sloan Kettering Cancer Center | 2023-03-15 |
| TPN-101 in Aicardi-Goutières Syndrome (AGS) (NCT05613868) | Transposon Therapeutics, Inc. | 2023-03-15 |
| Evaluating Buspirone to Treat Opioid Withdrawal (NCT05511909) | University of Maryland, Baltimore | 2023-03-15 |
| Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study) (NCT05482893) | Phanes Therapeutics | 2023-03-15 |
| Iron Replacement to Reduce Anemia During Neoadjuvant Chemotherapy (NCT05800600) | Fox Chase Cancer Center | 2023-03-15 |
| Effect of Moringa Leaf Capsules on Glycemic Control of Type 2 Diabetic Patients (NCT06125873) | Islamabad Medical and Dental College | 2023-03-15 |
| Combination of an Anti-PD1 Antibody With Tisagenlecleucel Reinfusion in Children, Adolescents and Young Adults With Acute Lymphoblastic Leukemia After Loss of Persistence (NCT05310591) | Assistance Publique - Hôpitaux de Paris | 2023-03-15 |
| A Study of HST-1011 Given as Monotherapy and in Combination With an Anti-PD1 Antibody (NCT05662397) | HotSpot Therapeutics, Inc | 2023-03-15 |
| Efficacy Evaluation of Sabizabulin Monotherapy Versus Active Control for Treatment of ER+HER2- Metastatic Breast Cancer (NCT05079360) | Veru Inc. | 2023-03-15 |
| Thrombosomes® in Acute Thoracic Aortic Dissections (NCT05771831) | Jakob Stensballe, MD, PhD | 2023-03-15 |
| A First-In-Human Trial of pTTL in Advanced Colorectal Cancer (NCT05908643) | Neogap Therapeutics AB | 2023-03-15 |
| Trial of PRO1160 (GEN1160) in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) (PRO1160-001) (NCT05721222) | Genmab | 2023-03-15 |
| Evaluate the Efficacy and Safety of Serplulimab Plus Chemotherapy in Neoadjuvant and Adjuvant Treatment of Resectable NSCLC (ECTOP-1013) (NCT05775796) | Fudan University | 2023-03-15 |
| Efficacy of a Probiotic Blend to Reduce Gastrointestinal Symptoms in Patients With Irritable Bowel Syndrome (NCT05819281) | Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude | 2023-03-15 |
| The Efficacy of a Probiotic Blend on Stress in Moderately Stressed Teens (NCT05766306) | Lallemand Health Solutions | 2023-03-15 |
| Tislelizumab in Combination With Pre-operative CRT Versus SOC for Locally Advanced G/GEJ Adenocarcinoma (NCT05687357) | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 2023-03-15 |
| A Study of Tobemstomig Plus Platinum-Based Chemotherapy vs Pembrolizumab Plus Platinum-Based Chemotherapy in Participants With Previously Untreated Non-Small Cell Lung Cancer (NCT05775289) | Hoffmann-La Roche | 2023-03-15 |
| A Study of Tafasitamab and Lenalidomide in People With Mantle Cell Lymphoma (NCT05788289) | Memorial Sloan Kettering Cancer Center | 2023-03-14 |
| A Study of Bi-Ligand-Drug Conjugate CBP-1019 in Patients With Advanced Solid Tumors (NCT05830097) | Coherent Biopharma (Hefei) Co., Ltd. | 2023-03-14 |
| Induction Therapy With PD-1 Antibody Combined With Platinum-based Doublet Chemotherapy for Locally-advanced Non-small Cell Lung Cancer (NCT05766800) | Shanghai Pulmonary Hospital, Shanghai, China | 2023-03-14 |
| Efficacy of PErioperative PEmbrolizumab Treatment in Patients With Resectable Metastases From Kidney Cancer (NCT05578664) | Consorzio Oncotech | 2023-03-14 |
| Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study (NCT05695027) | Columbia University | 2023-03-14 |
| TArgeting Type 1 Diabetes Using POLyamines (TADPOL) (NCT05594563) | Emily K. Sims | 2023-03-14 |
| Lymphoscintigraphy Directed Elective Neck Radiation for p16+ Favorable Risk Oropharynx Cancer (NCT05800574) | Fox Chase Cancer Center | 2023-03-14 |
| Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome (NCT05789056) | Quoin Pharmaceuticals | 2023-03-14 |
| Relevance Evaluation of [68Ga]Ga-PentixaFor for Initial Staging and Detection of Minimal Residual Disease in Multiple Myeloma Patients. (NCT05321862) | Nantes University Hospital | 2023-03-14 |
| Ph1b/2 Study of the Safety and Efficacy of SHR-A1811 Combinations in Advanced HER2 Expression Gastric Cancer (NCT05671822) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2023-03-14 |
| Pediatric Study of GVHD Ppx w/o Calcineurin Inhibitors After Day60 Post First Allo HSCT for Hematological Malignancies. (NCT05579769) | St. Jude Children's Research Hospital | 2023-03-14 |
| Different Targeted Antibody-drug Conjugates For HER2 Ultra-low or No Expression Advanced Breast Cancer（GALAXY） (NCT05824325) | Fudan University | 2023-03-14 |
| A Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors (NCT05706129) | Lumara Bio Oncologics GmbH | 2023-03-14 |
| Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population (NCT05580458) | National Institute of Allergy and Infectious Diseases (NIAID) | 2023-03-13 |
| A Pivotal Study to Evaluate the Efficacy of Lorundrostat in Subjects With Uncontrolled Hypertension on a Standardized Antihypertensive Medication Regimen (NCT05769608) | Mineralys Therapeutics Inc. | 2023-03-13 |
| An Open-Label Exploratory Study of Fosigotifator in Participants With Vanishing White Matter Disease (NCT05757141) | Calico Life Sciences LLC | 2023-03-13 |
| Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers (NCT05063552) | National Cancer Institute (NCI) | 2023-03-13 |
| A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors (NCT05795595) | CRISPR Therapeutics AG | 2023-03-13 |
| Lenrispodun as Adjunctive Therapy in the Treatment of Patients With Motor Fluctuations Due to Parkinson's Disease (NCT05766813) | Intra-Cellular Therapies, Inc. | 2023-03-13 |
| A Study of Treprostinil to Treat Interstitial Lung Disease Pulmonary Hypertension (NCT05564637) | Mayo Clinic | 2023-03-13 |
| Study of Efficacy, Safety, Tolerability and Pharmacokinetics of MIJ821 in Participants With Treatment- Resistant Depression (TRD) (NCT05454410) | Novartis Pharmaceuticals | 2023-03-13 |
| Neoadjuvant of Tislelizumab Combined With Chemotherapy Followed by Surgery in Unresectable Stage Ⅲ NSCLC (NCT05611879) | Beijing Tsinghua Chang Gung Hospital | 2023-03-12 |
| Study of LQT-1213 on QTc-induced Prolongation in Healthy Adult Subjects (Part1) and on Congenital Long QT in Patients Diagnosed With Type 2 or 3 Long QT Syndrome (Part 2). (NCT05906732) | Thryv Therapeutics, Inc. | 2023-03-12 |
| APalutamiAPalutamide and stEReotactic Body Radiation Therapy for Metastatic Prostate Cancer (NCT05717660) | Azienda Ospedaliero-Universitaria Careggi | 2023-03-11 |
| Study of TU2218 in Combination With KEYTRUDA®(Pembrolizumab) in Patients With Advanced Solid Tumors (NCT05784688) | TiumBio Co., Ltd. | 2023-03-10 |
| Study of WPV01 Compared With Placebo in Patients With Mild/Moderate COVID-19 Infection (NCT05752175) | Westlake Pharmaceuticals (Hangzhou) Co., Ltd. | 2023-03-10 |
| A Study of Oral Minoxidil to Treat Hair Loss in Children, Teens, and Young Adults Who Are Cancer Survivors (NCT05778825) | Memorial Sloan Kettering Cancer Center | 2023-03-10 |
| Using Fostamatinib to Treat Post-Hematopoietic Stem Cell Transplant Immune-mediated Cytopenias (NCT05502783) | National Heart, Lung, and Blood Institute (NHLBI) | 2023-03-10 |
| A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies (NCT05643742) | CRISPR Therapeutics AG | 2023-03-10 |
| Alpha-Lipoic Acid in Patients With Sepsis (NCT05808946) | Ain Shams University | 2023-03-10 |
| A Phase 1/2 Study to Evaluate ALN-KHK in Overweight to Obese Healthy Volunteers and Obese Patients With T2DM (NCT05761301) | Alnylam Pharmaceuticals | 2023-03-10 |
| Capeox Regimen Combined With Sintilimab and Bevacizumab for Gastric Cancer (NCT05640609) | West China Hospital | 2023-03-10 |
| Study of CM310 Injection in Subjects With Moderate-to-Severe Atopic Dermatitis (NCT05715320) | Keymed Biosciences Co.Ltd | 2023-03-10 |
| IBI310 in Combination With Sintilimab in Patients With Advanced Biliary Tract Cancer (NCT05653180) | Innovent Biologics (Suzhou) Co. Ltd. | 2023-03-10 |
| Neoadjuvant Toripalimab for dMMR/MSI-H Gastric Cancer (NCT05994456) | Sun Yat-sen University | 2023-03-09 |
| Sex Hormone Supplementation and Rotator Cuff Repair: A Preliminary Randomized Trial (NCT04944836) | University of Utah | 2023-03-09 |
| Study Evaluating the Benefit of Adding Ipilimumab to the Combination of Atezolizumab and Bevacizumab in Patients With Hepatocellular Carcinoma Receiving First-line Systemic Therapy (NCT05665348) | Federation Francophone de Cancerologie Digestive | 2023-03-09 |
| A Study to Assess the Efficacy and Tolerance of HRS-2261 in Subjects With Refractory Chronic Cough (NCT05733533) | Guangdong Hengrui Pharmaceutical Co., Ltd | 2023-03-09 |
| L19IL2/L19TNF in Skin Cancer Patients (NCT05329792) | Philogen S.p.A. | 2023-03-09 |
| A Study of BLB-201 RSV Vaccine in Infants and Children (NCT05655182) | Blue Lake Biotechnology Inc. | 2023-03-09 |
| The Effects of Suvorexant on Sleep, Stress, and Cue-reactivity in Methamphetamine Use Disorder (NCT05711862) | The University of Texas Health Science Center, Houston | 2023-03-09 |
| Dynamic Treatment Regiments for Glucocorticoid Tapering (NCT06072768) | VA Office of Research and Development | 2023-03-09 |
| Role of the Fibroblast Activation Protein (FAP) as Biomarker of Fibrotic Lung Diseases (NCT06189820) | Erasme University Hospital | 2023-03-09 |
| Atezolizumab and Bevacizumab Plus TACE-HAIC for Unresectable Advanced HCC: a Phase 2 Clinical Trial (NCT05751343) | Sun Yat-sen University | 2023-03-09 |
| Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer (NCT05557877) | Mayo Clinic | 2023-03-09 |
| HSK16149 for Perioperative Analgesia in Orthopedic Surgery (NCT06007066) | Haisco Pharmaceutical Group Co., Ltd. | 2023-03-08 |
| Efficacy and Safety of the Combination of Trastuzumab Plus TUCAtinib Plus viNorelbine in Patients With HER2-positive Non-resectable Locally Advanced or Metastatic Breast Cancer (NCT05583110) | Spanish Breast Cancer Research Group | 2023-03-08 |
| A Safety and Antitumor Activity Trial of Immunoradiotherapy Combinations as a Treatment Option for Subjects With Metastatic Solid Tumors (NCT05491317) | Genmab | 2023-03-08 |
| Tafasitamab (MOR00208) in Pediatric Patients With Relapsed or Refractory Acute B Lineage Leukemia (NCT05366218) | University Hospital Tuebingen | 2023-03-08 |
| Study to Improve Deployment Related Asthma by Using L-Citrulline Supplementation (NCT05259904) | University of Colorado, Denver | 2023-03-08 |
| A Study Evaluating Daily Oral Doses of TLC-3595 in Participants With Insulin Resistance (NCT05665751) | OrsoBio, Inc | 2023-03-08 |
| Efficacy, Safety, and Pharmacodynamics of Tislelizumab Monotherapy and Multiple Tislelizumab-based Immunotherapy Combinations in Participants With Resectable Non-Small Cell Lung Cancer (NCT05577702) | BeiGene | 2023-03-08 |
| NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours (NCT05714553) | NuCana plc | 2023-03-08 |
| CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors (NCT05733000) | Northwestern University | 2023-03-08 |
| Nimotuzumab Combined With Sintilimab and Chemotherapy for Advanced Esophageal Squamous Cell Carcinoma (NCT06718205) | The First Affiliated Hospital of Zhengzhou University | 2023-03-08 |
| A Clinical Study That Will Measure How Well SEP-363856 Works and How Safe it is in Adults With Generalized Anxiety Disorder (NCT05729373) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2023-03-08 |
| Use of Bleomycin in the Sclerotherapy of Lymphatic Malformations for Pediatric Patients (NCT06437158) | West China Hospital | 2023-03-08 |
| Utidelone Injection Combined With Gemcitabine in First-line Chemotherapy for Unresectable Advanced Pancreatic Cancer (NCT05795920) | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 2023-03-08 |
| E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers (NCT05686226) | Christian Hinrichs | 2023-03-07 |
| Anti-CCR4 Monoclonal Antibody (Mogamulizumab) and Total Skin Electron Beam Therapy (TSEB) in Patients With Stage IB-IIB Cutaneous T-Cell Lymphoma (NCT04128072) | European Organisation for Research and Treatment of Cancer - EORTC | 2023-03-07 |
| Study of Low-Dose Radiotherapy Concurrent Chemotherapy With Serplulimab for Patients With ES-SCLC (NCT05765825) | Sichuan University | 2023-03-07 |
| Assessment of Safety, Tolerability, Systemic Exposure and Efficacy of GPB Cream in Adolescents With Severe Primary Hyperhidrosis (NCT05863104) | Dr. August Wolff GmbH & Co. KG Arzneimittel | 2023-03-07 |
| DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With HER2 Amplification or Activating Mutations (NCT05786716) | Cancer Research UK | 2023-03-07 |
| Propranolol in Combination With Pembrolizumab and Standard Chemotherapy for the Treatment of Unresectable Locally Advanced or Metastatic Esophageal or Gastroesophageal Junction Adenocarcinoma (NCT05651594) | Roswell Park Cancer Institute | 2023-03-07 |
| Erdafitinib Monotherapy or in Combination With Cetrelimab in Muscle-invasive Bladder Cancer Patients With Fibroblast Growth Factor Receptor (FGFR ) Gene Alterations (NCT06511648) | Spanish Oncology Genito-Urinary Group | 2023-03-07 |
| An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH) (NCT05649748) | Insmed Incorporated | 2023-03-07 |
| A Study of Tislelizumab in Combination With Investigational Agents in Participants With Non-Small Cell Lung Cancer (NCT05635708) | BeiGene | 2023-03-07 |
| Tucatinib Together With Pembrolizumab and Trastuzumab (NCT04789096) | Breast Cancer Trials, Australia and New Zealand | 2023-03-07 |
| A Study of the Effects of Oxytocin in Adults With Binge-eating Disorder (NCT05664516) | Massachusetts General Hospital | 2023-03-07 |
| Preoperative PRRT Versus Surgical Cytoreduction in Metastatic Pancreatic Neuroendocrine Tumors to the Liver (NCT05610826) | University of Chicago | 2023-03-07 |
| Immunogenicity of Zoster Vaccine in Allogeneic Hematopoietic Stem Cell Transplant Recipients (NCT05554068) | Loyola University | 2023-03-07 |
| Acute Equol Supplementation and Vascular Function in Women With and Without CKD (NCT06128278) | University of Colorado, Denver | 2023-03-07 |