| Pemigatinib Combined With PD-1 Inhibitor in Unresectable or Metastatic Intrahepatic Cholangiocarcinoma (NCT05913661) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2023-07-01 |
| Cytokine-induced Memory-like NK Cells in Combination With Chemotherapy in Pediatric Patents With Refractory or Relapsed AML (NCT04354025) | Washington University School of Medicine | 2023-06-30 |
| 3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial (NCT05674396) | M.D. Anderson Cancer Center | 2023-06-30 |
| Phase II Study of PARP Inhibitor Olaparib and IV Ascorbate in Castration Resistant Prostate Cancer (NCT05501548) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2023-06-30 |
| A Study of Magnesium and Bladder Spasms Following Ambulatory Urologic Procedures (NCT05806996) | Mayo Clinic | 2023-06-30 |
| Study of the Efficacy and Safety of NST-1024 Versus Placebo in Subjects With Hypertriglyceridemia (NCT05889156) | NorthSea Therapeutics B.V. | 2023-06-30 |
| A Dose Escalation Study of FP-045 in Patients With Fanconi Anemia (NCT04522375) | Foresee Pharmaceuticals Co., Ltd. | 2023-06-30 |
| TRAC Locus-inserted CD19-targeting STAR-T Cell Therapy in r/r B-NHL (NCT05631912) | Chinese PLA General Hospital | 2023-06-30 |
| Combined Therapy Using D-TACE, Gemcitabine and Cisplatin, and PD1 Antibody in Advanced and Unresectable Intrahepatic Cholangiocarcinoma (NCT05738057) | Hua Li | 2023-06-30 |
| Pegylated Interferon α-2b in Combination With Ruxolitinib for Treating Hydroxyurea-resistant/Intolerant PV (NCT05870475) | Institute of Hematology & Blood Diseases Hospital, China | 2023-06-30 |
| Study to Evaluate the Efficacy and Safety of Ampligen in Patients With Post-COVID Conditions (NCT05592418) | AIM ImmunoTech Inc. | 2023-06-30 |
| A Study to Learn if a Combination of Fianlimab and Cemiplimab Versus Cemiplimab Alone is More Effective for Adult Participants With Advanced Non-Small Cell Lung Cancer (NSCLC) (NCT05785767) | Regeneron Pharmaceuticals | 2023-06-30 |
| Study to Evaluate R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients With Hepatorenal Syndrome (NCT05875948) | River 2 Renal Corp. | 2023-06-30 |
| Intrathecal Chemoprophylaxis to Prevent Neurotoxicity Associated With Blinatumomab Therapy for Acute Lymphoblastic Leukemia (NCT05519579) | Northside Hospital, Inc. | 2023-06-30 |
| Study of ART6043 in Advanced/Metastatic Solid Tumors Patients (POLKA) (NCT05898399) | Artios Pharma Ltd | 2023-06-30 |
| The Effect of Sildenafil Citrate on Frozen Embryo Transfer Cycles (NCT05951413) | Beni-Suef University | 2023-06-30 |
| A Study to Evaluate 611 in Patients With Chronic Rhinosinusitis With Nasal Polyps (NCT05865496) | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 2023-06-30 |
| NBP in Women With Metastatic Breast Cancer to Prevent Nab-paclitaxel Induced Toxic Neuropathy (NCT04675450) | Conjupro Biotherapeutics, Inc. | 2023-06-30 |
| A Study of JZP541 in Adults With Irritability Associated With Autism Spectrum Disorder (NCT05733390) | Jazz Pharmaceuticals | 2023-06-30 |
| Enfortumab Vedotin in Previously Treated Locally Advanced or Metastatic Pancreatic Cancer (EPIC) (NCT05915351) | University of Kansas Medical Center | 2023-06-30 |
| PR3-AAV Resilient Remission or PRRR (NCT05376319) | Mayo Clinic | 2023-06-30 |
| Phase II Study of SY-3505 in Patients With ALK-positive NSCLC Who Have Failed Prior Second-Generation ALK TKI (NCT05869162) | Shouyao Holdings (Beijing) Co. LTD | 2023-06-30 |
| Phase 1b/2 Study of Combination 177Lu Girentuximab Plus Cabozantinib and Nivolumab in Treatment naïve Patients With Advanced Clear Cell RCC (NCT05663710) | M.D. Anderson Cancer Center | 2023-06-30 |
| A Clinical Study of a Preoperative Translational Therapy for Unresectable Gallbladder Cancer (NCT05919095) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2023-06-30 |
| Effect of Equol Supplementation on Arterial Stiffness and Cognition in Healthy Volunteers (NCT05741060) | Akira Sekikawa | 2023-06-29 |
| Therapies for Down Syndrome Regression Disorder (NCT05662228) | University of Colorado, Denver | 2023-06-29 |
| Tafasitamab and Lenalidomide Followed by Tafasitamab and ICE as Salvage Therapy for Transplant Eligible Patients With Relapsed/ Refractory Large B-Cell Lymphoma (NCT05821088) | David Bond, MD | 2023-06-29 |
| Genomics Guided Targeted Post-neoadjuvant Therapy in Patients With Early Breast Cancer (COGNITION-GUIDE) (NCT05332561) | German Cancer Research Center | 2023-06-29 |
| RP2/RP3 in Combination With Atezolizumab and Bevacizumab for the Treatment of Patients With CRC (NCT05733611) | Replimune, Inc. | 2023-06-29 |
| Brachytherapy (Iodine-125 Seeds) and Fluzoparib Combination Therapy for Advanced Unresectable Soft Tissue Sarcoma (NCT05894018) | Fujun Zhang | 2023-06-29 |
| A Study Evaluating the Effects of GLPG3667 Administered as Oral Treatment in Adult Participants With Active Systemic Lupus Erythematosus (NCT05856448) | Lakefront Biotherapeutics NV | 2023-06-28 |
| Study of PULSAR-ICI +/- IMSA101 in Patients With Oligometastatic NSCLC and RCC (NCT05846646) | ImmuneSensor Therapeutics Inc. | 2023-06-28 |
| Effect of N-acetyl Cysteine and Zinc in Management of Head and Neck Cancer Radiotherapy Induced Oral Mucositis (NCT06482034) | Mansoura University | 2023-06-28 |
| REPOSE Study: Reducing Delirium by Enhancing Postoperative Sleep With Suvorexant (NCT05733286) | Duke University | 2023-06-28 |
| A Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy Study of MBS303 in B-Cell NHL (NCT05806099) | Beijing Mabworks Biotech Co., Ltd. | 2023-06-28 |
| Combination Treatment of Belantamab Mafodotin and Venetoclax in Treatment of Relapsed and Refractory t(11;14) Multiple Myeloma (NCT05853965) | Universitätsklinikum Hamburg-Eppendorf | 2023-06-28 |
| Ursodeoxycholic Acid as add-on Therapy in Type 2 Diabetes Mellitus (NCT05902468) | Tanta University | 2023-06-28 |
| SCRT Followed by Camrelizumab Combined With Fluzoparib and Chemotherapy as Neoadjuvant Therapy for LARC (NCT06516445) | Huazhong University of Science and Technology | 2023-06-28 |
| A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease (NCT05531656) | Cognition Therapeutics | 2023-06-28 |
| The Efficacy and Safety of Temozolomide in SDH-deficient GIST (NCT05661643) | Asan Medical Center | 2023-06-28 |
| A Study of DB-1202 Monotherapy in Advanced Solid Tumors (NCT05785728) | DualityBio Inc. | 2023-06-28 |
| Pembrolizumab Plus Bevacizumab and Chemotherapy for Non-Squamous NSCLC Patients (NCT05751187) | Shanghai Chest Hospital | 2023-06-27 |
| A Nasal Treatment for COVID-19 (NCT05799521) | Indiana University | 2023-06-27 |
| Neoadjuvant Tislelizumab Plus Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer (NeoSPOT) (NCT06009861) | Peking University Hospital of Stomatology | 2023-06-27 |
| Transcutaneous Cervical Vagus Nerve Stimulation (tcVNS) in JIA (NCT05710640) | National Institute of Allergy and Infectious Diseases (NIAID) | 2023-06-27 |
| A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations (NCT05788536) | Regeneron Pharmaceuticals | 2023-06-27 |
| A Study of Giredestrant in Participants With Grade 1 Endometrial Cancer (NCT05634499) | Hoffmann-La Roche | 2023-06-27 |
| Psilocybin-Assisted Therapy for the Treatment of Cancer-Related Anxiety in Patients With Metastatic Cancer (NCT05847686) | University of Washington | 2023-06-27 |
| A Phase 2 Study of the Ketogenic Diet vs Standard Anti-cancer Diet Guidance for Patients With Glioblastoma in Combination With Standard-of-care Treatment (NCT05708352) | Cedars-Sinai Medical Center | 2023-06-27 |
| Lu-PSMA and Stereotactic Radiotherapy Versus Radiotherapy Alone for Prostate Cancer (LUST) (NCT05893381) | Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS | 2023-06-27 |
| A Study of Oral Decitabine/Cedazuridine in Combination With Magrolimab in Participants With Intermediate- to Very High-Risk Myelodysplastic Syndromes (MDS) (NCT05835011) | Astex Pharmaceuticals, Inc. | 2023-06-27 |
| Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm (NCT05600894) | National Cancer Institute (NCI) | 2023-06-27 |
| A Study of Remimazolam Tosilate for Prolonged Sedation in the ICU (NCT05913336) | Jiangsu HengRui Medicine Co., Ltd. | 2023-06-27 |
| A Study to Compare the Efficacy and Safety of HB1801 to Taxotere in Advanced Non-Small Cell Lung Cancer (NSCLC) (NCT05863325) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2023-06-27 |
| Cell Therapy With Treg Cells Obtained From Thymic Tissue (thyTreg) to Control the Immune Hyperactivation Associated With COVID-19 and/or Acute Respiratory Distress Syndrome (THYTECH2) (NCT06052436) | Hospital General Universitario Gregorio Marañon | 2023-06-27 |
| Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus (NCT05966480) | Alumis Inc | 2023-06-26 |
| Elimination of Minimal Residual Disease After Transplant (NCT05690984) | Medical College of Wisconsin | 2023-06-26 |
| CTS2190 Phase I /II Clinical Study in Patients (NCT06224387) | CytosinLab Therapeutics Co., Ltd. | 2023-06-26 |
| Safety and Efficacy of PMT Therapy of hPAP (NCT05761899) | Children's Hospital Medical Center, Cincinnati | 2023-06-26 |
| A Study of PM8002 (Anti-PD-L1/VEGF) in Combination With Chemotherapy in Patients With NSCLC (NCT05756972) | Biotheus Inc. | 2023-06-26 |
| Venetoclax in Addition to Sequential Conditioning With Fludarabine / Amsacrine / Ara-C (FLAMSA) + Treosulfan for Allogeneic Blood Stem Cell Transplantation in Patients With MDS, CMML or sAML (NCT05807932) | Heinrich-Heine University, Duesseldorf | 2023-06-26 |
| Social Safety Learning in the Brain Oxytocin System (NCT05968651) | University of Washington | 2023-06-26 |
| The Impact of Preoperative Olanzapine on Quality of Recovery After Discharge From Ambulatory Surgery (NCT05676294) | Yale University | 2023-06-26 |
| ADP-A2M4CD8 Monotherapy and in Combination With Nivolumab in HLA-A2+ Subjects With MAGE-A4 Positive Ovarian Cancer (SURPASS-3) (NCT05601752) | USWM CT, LLC | 2023-06-26 |
| Study to Determine the Safety and Efficacy of Ribociclib in Combination With Hormone Therapy and Hypofractionated Radiotherapy in Breast Cancer, With Positive Hormone Receptors and Negative HER2 Status, in Newly Diagnosed, Not Immediately Operable Elderly Patient (CALHYS) (NCT05664893) | Centre Antoine Lacassagne | 2023-06-26 |
| A Study of BL-B01D1 in Patients With Multiple Solid Tumors, Including Recurrent or Metastatic Gynecological Malignancies (NCT05803018) | Sichuan Baili Pharmaceutical Co., Ltd. | 2023-06-25 |
| SBRT Plus vNKT for Pancreatic Cancer (NCT05783076) | Changhai Hospital | 2023-06-25 |
| Oro-nasal Decontamination to Prevent Ventilator-associated Pneumonia (NCT05895773) | Menoufia University | 2023-06-24 |
| IPH5201 and Durvalumab in Patients With Resectable Non-Small Cell Lung Cancer (MATISSE) (NCT05742607) | Innate Pharma | 2023-06-23 |
| A Study of Efficacy and Safety of Pembrolizumab Plus Enfortumab Vedotin (EV) +/- Investigational Agents in First-Line Metastatic Urothelial Carcinoma (mUC) (MK-3475-04B/KEYMAKER-U04) (NCT05845814) | Merck Sharp & Dohme LLC | 2023-06-23 |
| TT-10 (PORT-6) and TT-4 (PORT-7) as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors (NCT04969315) | Portage Biotech | 2023-06-23 |
| Geriatric Assessment Guided Interventions to Accelerate Functional Recovery After CAR-T Therapy for Patients 60 Years and Older With B-cell Non-Hodgkin Lymphoma or Multiple Myeloma, GOCART Study (NCT06052826) | City of Hope Medical Center | 2023-06-23 |
| Oxaliplatin ± Nivolumab in Combination With Trifluridine/Tipiracil or 5-fluorouracile in Frail Patients With Advanced, Recurrent or Metastatic Gastric, Oesophageal or Gastroesophageal Junction Cancer (NCT05476796) | UNICANCER | 2023-06-23 |
| A Clinical Study of Efinopegdutide in Participants With Precirrhotic Nonalcoholic Steatohepatitis (NASH) (MK-6024-013) (NCT05877547) | Merck Sharp & Dohme LLC | 2023-06-23 |
| Randomized Clinical Trial in Parkinson's Disease Patients Using Pluripotent Adipose Stem Cells (PASCs) (NCT06141317) | ClusterXStem-Costa Rica | 2023-06-23 |
| Effect of Mizagliflozin Repeat Dosing on Adverse Events and Postprandial Glucose Excursions (NCT05721729) | Vogenx, Inc. | 2023-06-23 |
| Cisplatin (CIS) Administered As Dry Powder for Inhalation (DPI) in Patients with Stage IV Non-Small Cell Lung Cancer (NCT06896890) | Inhatarget Therapeutics | 2023-06-23 |
| Comparison of Outcomes Between Low Dose Emicizumab and Factor VIII in Clinically Severe Hemophilia A (NCT06155955) | Chulalongkorn University | 2023-06-22 |
| Phase II Randomized Trial of Bethesda Protocol Compared to Cambridge Method for Detection of Early Stage Gastric Cancer in CDH1 Mutation Carriers (NCT04535414) | National Cancer Institute (NCI) | 2023-06-22 |
| Maternal Probiotic Intervention to Improve Gut Health (NCT06196450) | International Centre for Diarrhoeal Disease Research, Bangladesh | 2023-06-22 |
| A Clinical Trial of Tolcapone in Obsessive Compulsive Disorder (NCT05624528) | University of Chicago | 2023-06-22 |
| Study to Investigate Improvement in Physical Function in SF-36 With Vericiguat Compared With Placebo in Participants With Post-COVID-19 Syndrome (NCT05697640) | Charite University, Berlin, Germany | 2023-06-22 |
| The Safety and Efficacy of Q-1802 Combined With XELOX in Gastrointestinal Tumors (NCT05964543) | QureBio Ltd. | 2023-06-21 |
| Downstaging Protocol Containing Immunotherapy for HCC Beyond the Milan Criteria Before Liver Transplantation (NCT05475613) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2023-06-21 |
| Epcoritamab and Rituximab for First-line Follicular Lymphoma (NCT05783609) | Reid Merryman, MD | 2023-06-21 |
| A Clinical Trial to Investigate Long-term Safety, Tolerability, and Efficacy of Weekly Subcutaneous Doses With TransCon CNP in Children and Adolescents With Achondroplasia (NCT05929807) | Ascendis Pharma Growth Disorders A/S | 2023-06-21 |
| Safety and Efficacy Study of S-309309 in Obese Adults (NCT05925114) | Shionogi | 2023-06-21 |
| A Safety And Efficacy Study Of HLA-G- Targeted CAR-T Cells IVS-3001 In Subjects With Previously Treated Advanced HLA-G-Positive Solid Tumors (NCT05672459) | M.D. Anderson Cancer Center | 2023-06-21 |
| QR052107B Tablets in Patients With Subacute Cough of Phase Ⅱ Study (NCT06920836) | Wuhan Createrna Science and Technology Co., Ltd | 2023-06-21 |
| Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration (NCT06087458) | Perceive Biotherapeutics, Inc. | 2023-06-21 |
| Proof of Concept Trial of Cannabis Derivatives in Neuropathic Pain (NCT05351801) | VA Office of Research and Development | 2023-06-21 |
| A Study of LY3454738 in the Treatment of Adult Participants With Moderate-to-Severe Atopic Dermatitis (NCT05911841) | Eli Lilly and Company | 2023-06-21 |
| A Single-arm, Open-label, Clinical Trial of Surufatinib/Serplulimab/Platinum/Etoposide in Neuroendocrine Carcinoma. (NCT05747729) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2023-06-21 |
| Stereotactic Body Radiotherapy Combined With Cadonilimab for Advanced Refractory Malignant Solid Tumors (NCT05915481) | Peking University Third Hospital | 2023-06-21 |
| A Study to Investigate Efficacy and Safety of Ceralasertib Plus Durvalumab in Participants Aged ≥ 18 Years With Advanced or Metastatic Non-small Cell Lung Cancer Whose Disease Progressed on or After Prior Anti-PD-(L)1 Therapy and Platinum-based Chemotherapy (NCT05941897) | AstraZeneca | 2023-06-21 |
| Cadonilimab Combined With Fruquintinib and SBRT as Athird-line and Posterior Line Treatment in Patients With MSS CRC (NCT06168786) | Huazhong University of Science and Technology | 2023-06-20 |
| Combination Therapy Between Doxycycline, Pentoxifylline, and Nitazoxanide in Sexually Active Men (NCT05897034) | Tanta University | 2023-06-20 |
| A Phase 2 Open-label Study to Evaluate the Activity of Etavopivat on Transcranial Doppler Velocities in Pediatric Patients With Sickle Cell Disease Who Are at Increased Risk for Primary Stroke (NCT05953584) | Forma Therapeutics, Inc. | 2023-06-20 |
| A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib as a Single Agent or in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation (NCT05789082) | Hoffmann-La Roche | 2023-06-20 |
| Study of MHB088C for Patients With Advanced Solid Malignant Tumors (NCT07102004) | Qilu Pharmaceutical Co., Ltd. | 2023-06-20 |