| LEU01101: Safety and Preliminary Efficacy of LEU011 in Solid Tumours. (NCT06193902) | Leucid Bio | 2023-11-13 |
| A Phase 2 Study of QLM3003 Ointment in Participants With Mild or Moderate Atopic Dermatitis (NCT06058000) | Qilu Pharmaceutical Co., Ltd. | 2023-11-13 |
| Trial of Efficacy and Safety of MC0518 Versus Best Available Therapy in Participants With Steroid-Refractory Acute Graft Versus Host Disease (NCT06075706) | medac GmbH | 2023-11-13 |
| Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 With Unresectable Metastatic Colorectal Cancer in Combination With IV Fluorouracil, Folinic Acid, and Bevacizumab (NCT06107413) | AbbVie | 2023-11-12 |
| Pucotenlimab Combined With Lenvatinib as a Neodjuvant Therapy for Non Clear Cell Renal Cell Carcinoma (NCT06129955) | Sun Yat-sen University | 2023-11-11 |
| Zanubrutinib in the Treatment of Relapsed/Refractory wAIHA (NCT05922839) | Chen Miao | 2023-11-11 |
| Feasibility of Individualized, Model-guided Optimization of Proton Beam Treatment Planning in Patients With Low Grade Glioma (NCT05964569) | University Hospital Heidelberg | 2023-11-11 |
| The Addition of Chloroquine to Chemoradiation for Glioblastoma, (NCT02432417) | Maastricht Radiation Oncology | 2023-11-10 |
| Safety and Efficacy of APRIL-BAFF-Bicephali CAR-T in Relapsed, Refractory Multiple Myeloma (NCT06132711) | Xuzhou Medical University | 2023-11-10 |
| Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy (NCT06411795) | Masonic Cancer Center, University of Minnesota | 2023-11-10 |
| Esketamine Combined With Pregabalin on CPSP in Spinal Patients. (NCT06117917) | Beijing Tiantan Hospital | 2023-11-10 |
| A Study of BL-B01D1, SI-B003 and BL-B01D1+SI-B003 in Patients With Extensive Stage Small Cell Lung Cancer (NCT05924841) | Sichuan Baili Pharmaceutical Co., Ltd. | 2023-11-10 |
| A Phase 2b Study to Evaluate the Efficacy and Safety of CBL-514 Injection for Reducing Subcutaneous Fat. (NCT06005441) | Caliway Biopharmaceuticals Co., Ltd. | 2023-11-10 |
| Strong Albumin Solutions in Patients With Septic Shock (NCT05208242) | Manchester University NHS Foundation Trust | 2023-11-10 |
| Safety and Efficacy of Targeting PP2A in Ovarian Clear Cell Carcinoma Using Dostarlimab and LB-100 (NCT06065462) | M.D. Anderson Cancer Center | 2023-11-10 |
| c-MET Inhibitor in Advanced Solid Tumors With c-MET Gene Aberration (NCT05882292) | Yonsei University | 2023-11-10 |
| High Versus Low Dose Nitroglycerin in Acute Pulmonary Edema (NCT06107465) | Alexandria University | 2023-11-10 |
| A Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis (NCT05890729) | Xentria, Inc. | 2023-11-10 |
| AG Combined With Immunotherapy and SBRT in Patients With Potentially Resectable Pancreatic Cancer (NCT06080854) | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 2023-11-10 |
| Ph2 Placebo-Controlled Study for Safety & Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Pts w/ Elevated Eye Pressure (NCT06144918) | Skye Bioscience, Inc. | 2023-11-09 |
| Evaluate the Safety, Tolerability of BAT6026 (NCT06094179) | Bio-Thera Solutions | 2023-11-09 |
| Phase I/II Study Evaluating PSMA Targeted Radionuclide Therapy in Adult Patients With Metastatic Clear Cell Renal Cancer (NCT06059014) | Centre Leon Berard | 2023-11-09 |
| Repurposing Atovaquone for the Treatment of Platinum-Resistant Ovarian Cancer (NCT05998135) | Emory University | 2023-11-09 |
| Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ZYIL1 in Patients With Amyotrophic Lateral Sclerosis (NCT05981040) | Zydus Lifesciences Limited | 2023-11-09 |
| Abiraterone and Prednisone or Darolutamide for the Treatment of Advanced Prostate Cancer (NCT06173362) | University of California, Davis | 2023-11-09 |
| A Study of BMS-986466 With Adagrasib With or Without Cetuximab in Participants With Kirsten Rat Sarcoma Virus Glycine 12 to Cysteine (KRAS G12C)-Mutant Solid Tumors (NCT06024174) | Bristol-Myers Squibb | 2023-11-09 |
| Tirzepatide: Reversal of Lipotoxicity and Adipose Tissue Dysfunction in Humans With Overweight/Obesity (NCT05912621) | Stanford University | 2023-11-09 |
| Phase 2 Study of SAR444656 in Adult Participants With Moderate to Severe Atopic Dermatitis (NCT06058156) | Sanofi | 2023-11-09 |
| Cetuximab and Envafolimab Plus mFOLFOXIRI as First-line Treatment for RAS/BRAF Wild-type, MSS, Unresectable Left-side Metastatic Colorectal Cancer (NCT05959356) | Sun Yat-sen University | 2023-11-09 |
| Fruquintinib Plus Camrelizumab and Capecitabine as Salvage Therapy After Progression on FOLFOXIRI-based First-line Treatment in Patients With Unresectable/Metastatic Colorectal Cancer (NCT06148402) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2023-11-08 |
| Safety and Pharmacokinetic Study of Oral MK-8527 QM in Participants at Low-Risk for HIV-1 Infection (MK-8527-007) (NCT06045507) | Merck Sharp & Dohme LLC | 2023-11-08 |
| Radiation Major Hepatectomy to Selectively Treat Large Unifocal Hepatocellular Carcinoma (NCT06178198) | Seoul National University Hospital | 2023-11-08 |
| A Study to Learn About How Elinzanetant Works and How Safe it is in Women Having Sleep Disturbances Associated With Menopause (NCT06112756) | Bayer | 2023-11-08 |
| Effects of a Widely Used Vaccine Adjuvant in Subjects With Early Alzheimer's Disease Double-blind Study to Assess the Safety and Efficacy of AD04 in Patients With Early Alzheimer's Disease - ADVANCE (NCT07107074) | ADvantage Therapeutics | 2023-11-08 |
| The Effect of Low Doses of Prednisone on the Prolongation of Pregnancy in Threatened Preterm Birth (NCT06103227) | University of Mostar | 2023-11-08 |
| Triple Immune Checkpoint Inhibition for Advanced or Metastatic PD-(L)1 Refractory Merkel Cell Carcinoma (NCT06056895) | University of Washington | 2023-11-08 |
| Pulmonary Hypertension SOLAR (NCT04778046) | Bastiaan Driehuys | 2023-11-08 |
| Single-Arm Comprehensive Ablative Bridging Irradiation I Prior to CD19 CAR-T In High-Risk R/R LBCL (NCT06104592) | H. Lee Moffitt Cancer Center and Research Institute | 2023-11-08 |
| Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation (NCT05909150) | Fernando Bacal | 2023-11-08 |
| Bacteriophage Therapy TP-102 in Patients With Diabetic Foot Infection (NCT05948592) | Technophage, SA | 2023-11-08 |
| A Neoadjuvant Study of Tislelizumab and SX-682 for Resectable Pancreas Cancer (NCT05604560) | Lei Zheng | 2023-11-08 |
| A Study to Evaluate LBL-007 in Combination With Tislelizumab Plus Chemotherapy in Participants With Unresectable Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma (NCT06010303) | BeiGene | 2023-11-08 |
| Safety, Tolerability, and Immunogenicity Study of a 31-Valent Pneumococcal Conjugate Vaccine (VAX-31) in Adults (NCT06151288) | Vaxcyte, Inc. | 2023-11-08 |
| A Study of Single Fraction Stereotactic Body Radiation Therapy (SBRT) Guided by Magnetic Resonance Imaging (MRI) in People With Liver Metastasis From Colorectal Cancer (NCT06130280) | Memorial Sloan Kettering Cancer Center | 2023-11-08 |
| Safety and Feasibility of Metformin for Sepsis Induced AKI (NCT05900284) | Hernando Gomez | 2023-11-08 |
| Study of Venetoclax and Azacitidine in Advanced BCR-ABL Negative Myeloproliferative Neoplasms (NCT05074355) | University Health Network, Toronto | 2023-11-08 |
| Study of Pyridostigmine With Ondansetron in Subjects With Anti-AchR Positive Myasthenia Gravis (NCT04226170) | DAS-MG, Inc | 2023-11-08 |
| A Study of GC101 TIL in Advanced Melanoma (BZ) (NCT06120712) | Shanghai Juncell Therapeutics | 2023-11-08 |
| A Phase 2 Study to Learn About a Monovalent Pneumococcal Conjugate Candidate in Healthy Toddlers (NCT06116591) | Pfizer | 2023-11-08 |
| A Study of STRO-002 in Chinese Adults With Epithelial Ovarian Cancer and Other Advanced Malignant Solid Tumors (NCT06238687) | Tasly Pharmaceutical Group Co., Ltd | 2023-11-08 |
| Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour Disorder (NCT05904717) | Syntara | 2023-11-08 |
| [90Y]Y-PTT Endoradiotherapy in CNS Lymphoma Patients (NCT06132737) | Pentixapharm AG | 2023-11-07 |
| CisPlatin plUs Gemcitabine and Nabpaclitaxel (GAP) as pReoperative Chemotherapy Versus Immediate Resection in patIents With resecTable BiliarY Tract Cancers (BTC) at High Risk for Recurrence (NCT06037980) | Gruppo Oncologico del Nord-Ovest | 2023-11-07 |
| A Study to Evaluate SAR441566 Efficacy and Safety in Adults With Rheumatoid Arthritis (NCT06073093) | Sanofi | 2023-11-07 |
| A Phase Ib/II Study Confirmed Inhibition of Autophagy Synergizes Anti-tumor Effect of High Dose CDK4/6i (NCT05953350) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2023-11-07 |
| A Study of ST-1898 for Unresectable or Metastatic Melanoma (NCT06359860) | Beijing Scitech-Mq Pharmaceuticals Limited | 2023-11-07 |
| A Trial to Study the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Dermatosis Papulosa Nigra (DPN) (NCT06099080) | DermBiont, Inc. | 2023-11-07 |
| Safety, PK, and Preliminary Efficacy of MBRC-101 in Advanced Refractory Solid Tumors (NCT06014658) | MBrace Therapeutics | 2023-11-07 |
| A Study to Evaluate the Safety of Human Allogeneic Bone-Marrow-Derived Mesenchymal Stromal Cell Product StromaForte for the Treatment of Knee Osteoarthritis (NCT06084988) | Cellcolabs Clinical SPV Limited | 2023-11-07 |
| A Canadian Trial of Bicalutamide in Patients Receiving Maintenance Avelumab for Metastatic Urothelial Cancer. (NCT06018116) | CHU de Quebec-Universite Laval | 2023-11-07 |
| Trial of Ixazomib for Kaposi Sarcoma (NCT04305691) | AIDS Malignancy Consortium | 2023-11-07 |
| Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) (NCT06122779) | Bristol-Myers Squibb | 2023-11-07 |
| Trial of Nab-sirolimus in Patients With Well-differentiated Neuroendocrine Tumors (NETs) of the Gastrointestinal Tract, Lung, or Pancreas Who Have Not Received Prior Treatment With mTOR Inhibitors (NCT05997056) | Aadi Bioscience, Inc. | 2023-11-07 |
| A Study of Deucravacitinib to Treat LPP and FFA (NCT06091956) | Mayo Clinic | 2023-11-07 |
| Phase II Trial of Immunotherapeutic HPV Vaccine PRGN-2009 With Pembrolizumab Before Standard Treatment in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal Cancer (NCT05996523) | National Cancer Institute (NCI) | 2023-11-07 |
| Effectiveness of CRD-4730 in Participants With Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) (NCT06005428) | Cardurion Pharmaceuticals, Inc. | 2023-11-07 |
| A Study to Evaluate Whether Participants With Melanoma Prefer Subcutaneous vs Intravenous Administration of Nivolumab and Nivolumab + Relatlimab Fixed-dose Combinations (NCT06101134) | Bristol-Myers Squibb | 2023-11-06 |
| Metabolically Fit CD19 CAR T-cell Therapy With CD34 Selection in Patients With CD19+ Relapsed/Refractory NHL, CLL/SLL (NCT05702853) | Medical University of South Carolina | 2023-11-06 |
| Efficacy and Safety of Infliximab Biosimilar in Treatment of Moderate to Severe Psoriasis; A Single-arm Clinical Trial (NCT06591273) | Services Institute of Medical Sciences, Pakistan | 2023-11-06 |
| A Study to Evaluate the Safety and Efficacy of AK120 in Subjects With Moderate to Severe Atopic Dermatitis (NCT06092762) | Akeso | 2023-11-06 |
| Systems Investigation of Vaccine Responses in Aging and Frailty (NCT05291676) | Yale University | 2023-11-06 |
| Safety and Efficacy of OCN19-overexpressed Human Umbilical Cord-derived Mesenchymal Stem Cells in the Treatment of Refractory Type 2 Diabetes Mellitus (NCT06727721) | Lu jin ，MD | 2023-11-06 |
| Clinical Trial to Study the Efficacy and Safety of Fluorothiazinone (N.F. Gamaleya NRCEM) in Prophylaxis of Nosocomial Bacterial Infections With Participation of Patients on MV (NCT06135350) | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | 2023-11-06 |
| Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 1 (NCT06004830) | Yale University | 2023-11-06 |
| Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF) (NCT05938465) | Exegi Pharma, LLC | 2023-11-06 |
| Study to Evaluate the Safety and Efficacy of PIPE-307 in Subjects With Relapsing-Remitting Multiple Sclerosis (NCT06083753) | Janssen Research & Development, LLC | 2023-11-06 |
| A Trial to Evaluate the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Seborrheic Keratosis (NCT06108024) | DermBiont, Inc. | 2023-11-06 |
| PROton Therapy for Post Surgical Treatment of GYNecologic Cancer (NCT05758688) | Abramson Cancer Center at Penn Medicine | 2023-11-06 |
| A Study of BL-B01D1, SI-B003 and BL-B01D1+SI-B003 in Patients With Recurrent or Metastatic Cervical Cancer and Other Gynecological Malignancies (NCT05990803) | Sichuan Baili Pharmaceutical Co., Ltd. | 2023-11-06 |
| Montelukast in Parkinson Disease (NCT06113640) | Mostafa Bahaa | 2023-11-05 |
| Oral Prednisone in Treating LCH of Bone in Childhood and Adolescence (NCT06078969) | Shanghai Changzheng Hospital | 2023-11-04 |
| Administration of Anti Tim-3/CD123 CAR-T Cell Therapy in Relapsed and Refractory Acute Myeloid Leukemia (rr/AML) (NCT06125652) | Xuzhou Medical University | 2023-11-04 |
| Neoadjuvant Treatment For Locally Advanced Thymic Cancer (NCT06019468) | Shanghai Pulmonary Hospital, Shanghai, China | 2023-11-04 |
| Combination Salvage Therapy With Venetoclax and Decitabine in Relapsed/Refractory AML (NCT06156579) | University Hospital Tuebingen | 2023-11-04 |
| Safety and Immunogenicity of GPO Seasonal Tetravalent Inactivated Split Virion Influenza Vaccine in Healthy Thais (NCT05895955) | Mahidol University | 2023-11-04 |
| TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II (NCT05848687) | Tanja Andrea Gruber | 2023-11-03 |
| Evaluation of Efficacy and Safety When Administered JP-2266 in Type 2 Diabetes Patients (NCT06144788) | Jeil Pharmaceutical Co., Ltd. | 2023-11-03 |
| Allogeneic BM-MSCs in Patients With Painful Lumbar Facet Arthropathy (NCT06001853) | Mayo Clinic | 2023-11-03 |
| A Study of Zetomipzomib (KZR-616) in Patients With Active Lupus Nephritis (PALIZADE) (NCT05781750) | Kezar Life Sciences, Inc. | 2023-11-03 |
| Relmacabtagene Autoleucel As Second-Line Therapy in Adult Patients with Aggressive B-cell NHL (NCT06093841) | Shanghai Ming Ju Biotechnology Co., Ltd. | 2023-11-03 |
| TheraSphere With Durvalumab and Tremelimumab for HCC (NCT05063565) | Boston Scientific Corporation | 2023-11-03 |
| A Clinical Trial on the Treatment of Idiopathic Pulmonary Fibrosis (NCT06102083) | Beijing Tide Pharmaceutical Co., Ltd | 2023-11-02 |
| Finding an Effective Dose of GM1 to Reduce or Prevent Neuropathy (Numbness or Weakness) Due to Treatment With Paclitaxel (Phase II) (NCT05751668) | Alliance for Clinical Trials in Oncology | 2023-11-02 |
| Department of Defense PTSD Adaptive Platform Trial - Intervention A - Fluoxetine (NCT05948553) | Global Coalition for Adaptive Research | 2023-11-02 |
| Department of Defense PTSD Adaptive Platform Trial - Master Protocol (NCT05422612) | Global Coalition for Adaptive Research | 2023-11-02 |
| Combination Study of Antibiotics With Enzalutamide (PROMIZE) (NCT06126731) | Institute of Cancer Research, United Kingdom | 2023-11-02 |
| Intravenous N-Acetylcysteine for the Treatment of Acute Ischemic Stroke (NCT04918719) | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 2023-11-02 |
| Hepatic Encephalopathy and Albumin Lasting Cognitive Improvement (NCT06052176) | Hunter Holmes Mcguire Veteran Affairs Medical Center | 2023-11-02 |
| Open-Label Extension of EDG-5506 in Participants With Becker Muscular Dystrophy (NCT06066580) | Edgewise Therapeutics, Inc. | 2023-11-02 |
| Mitochondrial Capacity Boost in ALS (MICABO-ALS) Trial (NCT04244630) | Dallas VA Medical Center | 2023-11-02 |