| Efficacy and Safety of LP-003 in Patients With CSU Who Remain Symptomatic Despite Antihistamine (H1) Treatment (NCT06228560) | Longbio Pharma | 2024-01-26 |
| Phase II Clinical Trial to Evaluate the Efficacy and Safety of LPM3480392 Injection for Moderate to Severe Pain After Orthopedic Surgery (NCT06467409) | Luye Pharma Group Ltd. | 2024-01-26 |
| Study to Evaluate NRCT-101SR in Pediatric Subjects With ADHD (NCT06215144) | Neurocentria, Inc. | 2024-01-25 |
| An Open-Label Study of CTI-1601 in Subjects With Friedreich's Ataxia (NCT06447025) | Larimar Therapeutics, Inc. | 2024-01-25 |
| Neural Stem Cell Treatment for Amyotrophic Lateral Sclerosis (STEMALS) (NCT06344260) | Casa Sollievo della Sofferenza IRCCS | 2024-01-25 |
| Safety, PK and PD Relationships of RLS-0071 in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease (NCT06175065) | ReAlta Life Sciences, Inc. | 2024-01-25 |
| Upadacitinib for Refractory Behcet's Syndrome (NCT07080346) | Liu Tian | 2024-01-25 |
| A Prospective Randomized Controlled Study of Immune Checkpoint Maintenance Therapy After Radiotherapy and Chemotherapy for Locally Advanced Head and Neck Tumors Based on Peripheral Blood CD8Tex Detection in Peripheral Blood (NCT06240689) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2024-01-25 |
| Envafolimab Combined With Chemotherapy in Neoadjuvant and Conversion Therapy for Head and Neck Squamous Cell Carcinoma (NCT06218004) | Hairong Liu | 2024-01-25 |
| Phase II Study of Moderate-dose Hypofractionated RT Combined With Tislelizumab for HCC With Diffuse Tumor Thrombosis (NCT06233981) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2024-01-25 |
| Safety and Efficacy of LX102 Gene Therapy in Patients With Neovascular Age-related Macular Degeneration (nAMD) (VENUS) (NCT06196840) | Innostellar Biotherapeutics Co.,Ltd | 2024-01-24 |
| Lenalidomide and Epcoritamab for the Treatment of Previously Untreated Follicular Lymphoma (NCT06112847) | City of Hope Medical Center | 2024-01-24 |
| Kinesiotaping Method for Rib Fractures (NCT06222320) | Kastamonu University | 2024-01-24 |
| Shuxuening Injection for the Prevention of CVS in Patients With aSAH(SXN-CVS) (NCT06138353) | Xiaolin Chen, MD | 2024-01-24 |
| Study to Evaluate the Efficacy and Safety of Satralizumab in FSHD1 (NCT06222827) | Centre Hospitalier Universitaire de Nice | 2024-01-24 |
| Trial Evaluating the Efficacy and the Safety of FOLFIRINOX3 Treatment in Patients With Unresectable Locally Advanced or Metastatic Pancreatic Cancer in First Line of Chemotherapy (NCT05988814) | Centre Georges Francois Leclerc | 2024-01-24 |
| Study of Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in Virologically Suppressed Children Living With HIV-1, Two to Less Than 12 Years of Age (NCT05660980) | National Institute of Allergy and Infectious Diseases (NIAID) | 2024-01-24 |
| Effects of TNF Blockade on Human BPH/LUTS (NCT06062875) | Endeavor Health | 2024-01-24 |
| An Open-Label, Multiple-Center, Phase IIa/IIb Clinical Trial to Evaluate the Efficacy, Safety and Tolerability of VG161 as Monotherapy and in Combination With Nivolumab for Treatment of Patients With Hepatocellular Carcinoma or Intrahepatic Cholangiocarcinoma (NCT05223816) | Virogin Biotech Canada Ltd | 2024-01-24 |
| Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2) (NCT06225596) | BicycleTx Limited | 2024-01-24 |
| A Study of Continued Treatment With Regorafenib in Participants With Solid Tumors Who Have Participated in Other Bayer Studies (NCT06246643) | Bayer | 2024-01-24 |
| Treatment of Post-Punch Biopsy Bleeding in Apixaban-Treated Patients Using Self-Administered BXP154B (NCT06205615) | Bio 54, LLC | 2024-01-24 |
| Platform Study to Evaluate the Efficacy and Safety of Anti-malarial Agents in Patients With Uncomplicated Plasmodium Falciparum Malaria (NCT05750628) | Novartis Pharmaceuticals | 2024-01-23 |
| Platform Study to Evaluate the Efficacy and Safety of Anti-malarial Agents in Participants With Uncomplicated Plasmodium Falciparum Malaria (NCT07235020) | Novartis Pharmaceuticals | 2024-01-23 |
| A Window-of-Opportunity Trial of Giredestrant +/- Triptorelin vs. Anastrozole + Triptorelin in Premenopausal Patients With ER-positive/HER2-negative Early Breast Cancer (NCT05896566) | ETOP IBCSG Partners Foundation | 2024-01-23 |
| Tolerance and Efficacy Nicotinamide (Vitamin B3) in Dominant Optic Atrophy OPA1 (NCT06007391) | University Hospital, Angers | 2024-01-23 |
| Platform Study to Evaluate the Efficacy and Safety of Anti-malarial Agents in Participants With Uncomplicated Plasmodium Falciparum Malaria (Cohort B2) (NCT07235033) | Novartis Pharmaceuticals | 2024-01-23 |
| Comparing the Effectiveness of the Immunotherapy Agents Rituximab or Mosunetuzumab in Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma, NORM Trial (NCT05886036) | National Cancer Institute (NCI) | 2024-01-23 |
| Induction Chemotherapy Plus Cadonilimab for Locally Advanced Cervical Cancer (NCT06511726) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2024-01-23 |
| Organ Protective Effect of Cetirizine In Patients With Severe Burns (NCT06126991) | Ruijin Hospital | 2024-01-23 |
| A Clinical Trial to Evaluate Efficacy and Safety of TransCon CNP Compared With Placebo in Infants (0 to <2 Years of Age) With Achondroplasia (NCT06079398) | Ascendis Pharma A/S | 2024-01-23 |
| Cadonilimab in Patients (Pts) with Advanced Non-small Cell Lung Cancer (NSCLC) (NCT06793813) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2024-01-23 |
| Safety and Efficacy of RVU120 for Treatment of Relapsed/Refractory AML (NCT06268574) | Ryvu Therapeutics SA | 2024-01-23 |
| AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies. (NCT06137144) | AstraZeneca | 2024-01-23 |
| Customized CAD/CAM Titanium-Milled Abutments Vs. Custom Abutments Over Immediate Implants in Class II Extraction Sockets in the Esthetic Zone: a Randomized Controlled Clinical Trial (NCT06791655) | Ain Shams University | 2024-01-22 |
| DEWI: Watch-and-Wait With Dostarlimab in Localized dMMR/MSI-H Gastric/GEJ Adenocarcinoma Phase II Study (NCT06059495) | GERCOR - Multidisciplinary Oncology Cooperative Group | 2024-01-22 |
| Ph2 Open-label Study of AOC 1044 in Duchenne Muscular Dystrophy Participants With Mutations Amenable to Exon44 Skipping (NCT06244082) | Avidity Biosciences, Inc. | 2024-01-22 |
| Phase 2 Study of Glofitamab Monotherapy & With Polatuzumab Vedotin, Pirtobrutinib, or Atezolizumab in Richter's Transformation (NCT06043674) | Christine Ryan | 2024-01-22 |
| A Three-arm Randomized Phase II Study of Dostarlimab Alone or With Bevacizumab Versus Nonplatinum Chemotherapy in Recurrent Gynecological Clear Cell Carcinoma: DOVE (APGOT-OV7/ ENGOT-ov80 Study) (NCT06023862) | Yonsei University | 2024-01-22 |
| A Safety and Efficacy Study of 2 Dosing Regimens of Recombinant Human Nerve Growth Factor (rhNGF) Eye Drop Solution Compared With Vehicle in Patients With Dry Eye Disease. (NCT06244316) | Dompé Farmaceutici S.p.A | 2024-01-22 |
| Minocyclin in Ulcerative Colitis as Added on Therapy (NCT06201793) | Mostafa Bahaa | 2024-01-22 |
| A Study to Evaluate Allogenic Bone-Marrow Mesenchymal Stromal Cell Product StromaForte in Aging Frailty Patients (NCT06063590) | Cellcolabs Clinical SPV Limited | 2024-01-22 |
| Dose Exploration Study of GSK4532990 in. Participants With NASH or Suspected NASH (NCT06104319) | GlaxoSmithKline | 2024-01-22 |
| Darsilide Combined With AI, Trastuzumab and Patuzumab in the Neoadjuvant Treatment of HR+/HER2+ Breast Cancer (NCT06276868) | Henan Cancer Hospital | 2024-01-20 |
| Irinotecan Liposome for Resectable Pancreatic Cancer With or Without Addebelizumab (NCT06172036) | Zhejiang University | 2024-01-20 |
| A Study of Trilaciclib Combined With mFOLFIRINOX in the Treatment of Patients With Advanced Pancreatic Cancer (NCT06151262) | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 2024-01-20 |
| A Study of BL-M07D1 in Patients With a Variety of Solid Tumors Including Locally Advanced or Metastatic HER2-positive/Low-expressing Urinary and Gastrointestinal Tumors (NCT06031584) | Sichuan Baili Pharmaceutical Co., Ltd. | 2024-01-19 |
| Thalidomide Prevention or Treatment of Camrelizumab-induced Reactive Cutaneous Capillary Endothelial Proliferation (RCCEP) (NCT06231680) | Henan Cancer Hospital | 2024-01-19 |
| RC88 in Platinum-Resistant Recurrent Epithelial Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer (NCT06173037) | RemeGen Co., Ltd. | 2024-01-19 |
| A Study to Assess the Efficacy, Safety and Tolerability of Different Doses of AZD0780 in Patients With Dyslipidemia (NCT06173570) | AstraZeneca | 2024-01-19 |
| Adebrelimab Plus Cetuximab and Chemotherapy for Patients With RAS/BRAF Wild-Type Unresectable Liver Metastases Colorectal Cancer (NCT06231017) | The First Affiliated Hospital of Zhengzhou University | 2024-01-19 |
| Neoadjuvant Therapy of HAIC（GEMOX） Combined With Adebrelimab and Lenvatinib for Resectable Intrahepatic Cholangiocarcinoma With High-risk Recurrence Factors (NCT06208462) | The First Affiliated Hospital with Nanjing Medical University | 2024-01-19 |
| A Phase I/II, Randomized, Double-blind, Placebo, and Active Controlled Clinical Study to Evaluate the Safety, Tolerability, Immunogenicity, and Preliminary Efficacy of JHM03 in Subjects With Moderate to Severe Glabellar Lines (NCT06199336) | JHM BioPharma (Tonghua) Co. , Ltd. | 2024-01-19 |
| The Effect of Daratumumab in Patients with Monoclonal Gammopathy of Renal Significance (MGRS) in Finland (NCT06889948) | Helsinki University Central Hospital | 2024-01-19 |
| CBD for Individuals at Risk for Alzheimer's Disease (NCT05822362) | University of Colorado, Denver | 2024-01-19 |
| A Phase 1b/2a, Study Evaluating the Safety, PK/PD and Efficacy of NS101 in Healthy Volunteers and SSNHL Patients (NCT06249919) | Neuracle Science Co., LTD. | 2024-01-19 |
| Open-Label Extension Study of ASTORIA (NCT05516875) | Contera Pharma A/S | 2024-01-19 |
| [18F]-MFBG Versus [123I]-MIBG and [18F]-PE2I in PD vs. MSA and DLB vs. AD (NCT06120049) | prof. dr. Koen Van Laere | 2024-01-19 |
| Efficacy and Safety of PD-L1 Monoclonal Antibody Combined With Metronomic VEX in Advanced Triple-negative Breast Cancer (NCT06229067) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2024-01-19 |
| Treating Respiratory Emergencies in Children Study (NCT06074185) | Oregon Health and Science University | 2024-01-19 |
| Treatment of CD19 Chimeric Antigen Receptor T Cells for Pediatric Patients With CD19-positive B-cell Acute Lymphoblastic Leukemia Who Are Indicated for Hematopoietic Stem Cell Transplantation (NCT06247501) | Seoul National University Hospital | 2024-01-19 |
| Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma (NCT05864534) | Northwestern University | 2024-01-19 |
| Phase 2b Study to Investigate the Safety and Efficacy of TIN816 in Sepsis-associated Acute Kidney Injury (CLEAR-AKI) (NCT05996835) | Novartis Pharmaceuticals | 2024-01-18 |
| Study of Intravenous Amisulpride for Prophylaxis of Post-operative Nausea and Vomiting (PONV) in Pediatric Patients (NCT05546359) | Acacia Pharma Ltd | 2024-01-18 |
| JSKN033 in Patients With Advanced or Metastatic Solid Malignant Tumors (NCT06226766) | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | 2024-01-18 |
| ARTEMIS-003: HS-20093 in Patients With Metastatic Castrate-resistant Prostate Cancer (mCRPC) and Advanced Solid Tumors (NCT06001255) | Hansoh BioMedical R&D Company | 2024-01-18 |
| Neoadjuvant PD-1 Inhibitor Combined With Cetuximab and Platinum in Resectable Locally Advanced Hypopharyngeal Carcinoma (NCT06151743) | Eye & ENT Hospital of Fudan University | 2024-01-18 |
| The COLchicine HEART Failure PRESERVED Trial (COLHEART-PRESERVED) (NCT06081049) | Tor Biering-Sørensen | 2024-01-18 |
| Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC (NCT06162221) | Revolution Medicines, Inc. | 2024-01-18 |
| Dyadic Financial Incentive Treatments for Dual Smoker Couples (NCT06296849) | University of Oklahoma | 2024-01-18 |
| A Study of AZD3470, a PRMT5 Inhibitor, Given as Monotherapy and in Combination in Patients With MTAP Deficient Advanced/Metastatic Solid Tumors (NCT06130553) | AstraZeneca | 2024-01-18 |
| DOAC in Patients with Child a or B Liver Cirrhosis (NCT05869591) | Centre Hospitalier Universitaire Vaudois | 2024-01-18 |
| eXtended Antibiotic Prophylaxis for Intermediate- and High-risk Glands After Pancreatoduodenectomy to Reduce CR-POPF (NCT05753735) | Case Comprehensive Cancer Center | 2024-01-18 |
| Safety and Tolerability of 1 Month Daily (1HP) and 3 Months Weekly (3HP) Isoniazid and Rifapentine With Pharmacokinetics of Dolutegravir (DTG) in Pregnant People With HIV (NCT05122026) | The Aurum Institute NPC | 2024-01-17 |
| Assessment of Psilocybin (TRP-8802) in Concert With Psychotherapy in Patients With Irritable Bowel Syndrome (IBS) (NCT06206265) | TRYP Therapeutics | 2024-01-17 |
| The Safety, Tolerability and Efficacy of NouvNeu001 for Parkinson's Disease (NCT06167681) | iRegene Therapeutics Co., Ltd. | 2024-01-17 |
| Discontinuation of CDK4/6 Inhibitors in Patients With Metastatic HR Positive, HER2 Negative Breast Cancer (NCT06207734) | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | 2024-01-17 |
| GVM±R in Patients With Relapsed or Refractory Aggressive NHL. (NCT06244368) | Institute of Hematology & Blood Diseases Hospital, China | 2024-01-17 |
| Efficacy and Safety of Mirabegron in Intracerebral Hemorrhage (NCT05369351) | Tianjin Medical University General Hospital | 2024-01-17 |
| A Trial to Assess Cobicistat Boosted Venetoclax in Combination With Azacitidine in Adult Patients With Newly Diagnosed AML (NCT06014489) | Stichting Hemato-Oncologie voor Volwassenen Nederland | 2024-01-17 |
| Upfront Maintenance Olaparib in Advanced Ovarian Cancer BRCAwt Patients With Known Homologous Recombination Deficiency (NCT06120972) | Alexander B Olawaiye, MD | 2024-01-17 |
| Intratumoral and Systemic Hiltonol® (Poly-ICLC) in Prostate Cancer Patients on Active Surveillance (NCT06343077) | Ashutosh Kumar Tewari | 2024-01-16 |
| Evaluation of Nitric Oxide Nasal Spray (NONS) for Treatment of Recurrent Acute Rhinosinusitis (NCT06264141) | Sanotize Research and Development corp. | 2024-01-16 |
| A Randomized, Double-blind, Placebo-controlled, and Multi-center Clinical Study of CM313 in the Treatment of Immune Thrombocytopenia (NCT06199089) | Institute of Hematology & Blood Diseases Hospital, China | 2024-01-16 |
| A Multicentre,Study of IBI133 in Subjects WithUnresectable, Locally Advanced or Metastatic SolidTumours (NCT06170190) | Innovent Biologics (Suzhou) Co. Ltd. | 2024-01-16 |
| Efficacy of a New Nanoemulsion Artificial Tear Targeting Dry Eye Disease (NCT06188260) | The Hong Kong Polytechnic University | 2024-01-16 |
| BEFAST Study, [68Ga]Ga-FAPI Total Body PET/CT for Better and Faster Imaging in Cancer (NCT07629609) | Barbara Malene Fischer | 2024-01-16 |
| Motivation for IV Alcohol Self-Administration in Humans (NCT06494891) | University of California, Los Angeles | 2024-01-16 |
| Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease (NCT05719714) | Northwestern University | 2024-01-16 |
| Proteomic Guided First-line Precision Treatment of Renal Clear Cell Carcinoma (NCT06211790) | Fudan University | 2024-01-16 |
| Trial of Tumor Vaccine Used for Adjuvant Therapy in Post Radical Operation Patients With Lung Cancer (NCT03807102) | Yongchang Zhang | 2024-01-16 |
| AGNOSTIC THERAPY IN A PHASE II SINGLE-ARM STUDY IN FIRST-LINE TREATMENT OF DURVALUMAB IN ASSOCIATION WITH CARBOPLATIN OR CISPLATIN AND ETOPOSIDE IN PATIENTS AFFECTED BY EXTENSIVE STAGE - EXTRAPULMONARY SMALL CELL CARCINOMA (NCT06464068) | Gruppo Oncologico Italiano di Ricerca Clinica | 2024-01-16 |
| A Single-Arm Study of Pembrolizumab With Gemcitabine and Cisplatin as Perioperative Therapy for Potentially Resectable Intrahepatic Cholangiocarcinoma (NCT05967182) | M.D. Anderson Cancer Center | 2024-01-16 |
| Study to Evaluate the Efficacy of Delpazolid as Add-on Therapy in Refractory Mycobacterium Abscessus Complex (NCT06004037) | LigaChem Biosciences, Inc. | 2024-01-16 |
| Tripegfilgrastim Trial to Reduce the Risk of Severe Neutropenia in Patients With Unresectable Pancreaticobiliary Cancers (NCT06135896) | National Cancer Center, Korea | 2024-01-16 |
| Dapagliflozin in Nonalcoholic Fatty Liver Disease (NAFLD) and Type 2 Diabetes Mellitus Patients (T2DM). (NCT07020377) | Amira Bisher,PhD | 2024-01-15 |
| PSMA-RLT in Biochemically Recurrent PCa (NCT06220188) | Medical University of Vienna | 2024-01-15 |
| Ca-Mg Butyrate in GWI (NCT05367245) | VA Office of Research and Development | 2024-01-15 |
| Study of EYP-1901 in Patients With Diabetic Macular Edema (DME) (NCT06099184) | EyePoint Pharmaceuticals, Inc. | 2024-01-15 |
| A Study to Learn More About How Well BAY3018250 Works and How Safe it is for People With Proximal Deep Vein Thrombosis (NCT06149520) | Bayer | 2024-01-15 |