| Evaluate the Safety and Efficacy of EN001 in Patients With Charcot-Marie-Tooth Disease Type 1A(CMT1A) (Phase 1b: Open-label, Dose-escalation, Single-center; Phase 2a: Randomized, Double-blind, Placebo-controlled, Multicenter) (NCT06328712) | ENCell | 2024-05-30 |
| MRD Guided Sonrotoclax and Zanubrutinib in Newly Diagnosed CLL/SLL (NCT06367374) | Institute of Hematology & Blood Diseases Hospital, China | 2024-05-30 |
| Study of ZG005 in Combination With Etoposide and Cisplatin in Participants With Advanced Neuroendocrine Carcinoma. (NCT06372626) | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 2024-05-30 |
| Phase II Study of Pirtobrutinib, Rituximab (PR) in Previously Untreated Low and Intermediate Risk MCL (Mantle Cell Lymphoma) Patients (NCT06263491) | M.D. Anderson Cancer Center | 2024-05-29 |
| A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM). (NCT06412666) | Cytokinetics | 2024-05-29 |
| Sequential CAR-T Cells Targeting BCMA/CD19 in Patients With Relapsed/ Refractory Autoimmune Diseases (NCT06428188) | Essen Biotech | 2024-05-29 |
| A Study of BRIA-OTS Cellular Immunotherapy in Metastatic Recurrent Breast Cancer (NCT06471673) | BriaCell Therapeutics Corporation | 2024-05-29 |
| Open-label, Single Center, Single-arm, Phase 2 Study of Neoadjuvant Pembrolizumab in Combination With Carboplatin and Paclitaxel in Patients With Stage 1 cT1b-T1cN0M0 Triple Negative Breast Cancer (NCT06318897) | M.D. Anderson Cancer Center | 2024-05-29 |
| Sodium Glycididazole Reduces the Adverse Reactions of Concurrent Chemoradiotherapy (NCT06667622) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2024-05-29 |
| Pembrolizumab Plus Bevacizumab and Chemotherapy for ALK-rearranged NSCLC With Persistent 5'ALK (NCT05266846) | Hunan Province Tumor Hospital | 2024-05-29 |
| A Study of BL-B01D1 + PD-1 in Patients With Locally Advanced or Metastatic Urothelial Carcinoma (NCT06405425) | Sichuan Baili Pharmaceutical Co., Ltd. | 2024-05-29 |
| Modulation of Gut Microbiota by Probiotic in Children (NCT06474234) | Min-Tze LIONG | 2024-05-29 |
| Personalised Timing of Interval Debulking Surgery in Advanced Ovarian Cancer (NCT07022535) | The University of Hong Kong | 2024-05-28 |
| Safety and Efficacy of Angiotensin (1-7) in Persons With Moderate to Severe Traumatic Brain Injury (NCT06282965) | University of Arizona | 2024-05-28 |
| Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression (NCT06419608) | Biohaven Therapeutics Ltd. | 2024-05-28 |
| Effect of Pregabalin Gel in Controlling Cervical Dentin Hypersensitivity (NCT06417580) | Jesuína Lamartine Nogueira Araújo | 2024-05-28 |
| BHV-7000 Acute Treatment of Bipolar Mania (NCT06419582) | Biohaven Therapeutics Ltd. | 2024-05-28 |
| Use of a Treated, Devitalized and Sterile Umbilical Cord Amniotic Membrane in the Treatment of STT Osteoarthritis (NCT06038331) | TBF Genie Tissulaire | 2024-05-28 |
| A Study of HS-20117 Combined With Aumolertinib in Participants With Advanced Non-Squamous Non-Small Cell Lung Cancer (NCT06417008) | Hansoh BioMedical R&D Company | 2024-05-28 |
| Linperlisib Combined With Immunochemotherapy in Relapsed/Refractory LBCL (NCT06489808) | Institute of Hematology & Blood Diseases Hospital, China | 2024-05-28 |
| A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of PB-119 Injection in Chinese Obese Subjects (NCT06350812) | PegBio Co., Ltd. | 2024-05-27 |
| Safety and Immunogenicity of a Sub-unit Protein CD40.RBDv Bivalent COVID-19 Vaccine, Adjuvanted or Not, as a Booster in Volunteers. (NCT06255626) | ANRS, Emerging Infectious Diseases | 2024-05-27 |
| A Study of Safety and Efficiency of AND017 in Patients With β-thalassemia (NCT06302491) | Kind Pharmaceuticals LLC | 2024-05-27 |
| Safety, Tolerability, Analgesic Effect, and Feasibility of Intranasal CT001 in Pediatric Patients (NCT06364072) | Cessatech A/S | 2024-05-27 |
| Phase II Study of Liposomal Irinotecan for Advanced Refractory Gastric Cancer (NCT06437678) | Zhejiang Cancer Hospital | 2024-05-27 |
| The Effect of Alpha Lipoid Acid and Vitamin B Preparation on Diabetic Polyneuropathy in Type 2 Diabetes Mellitus Patient (NCT06568185) | Universiti Sains Malaysia | 2024-05-27 |
| Clinical Trial to Evaluate BO-112 in Patients With Basal Cell Carcinoma (BCC) (NCT06422936) | Highlight Therapeutics | 2024-05-27 |
| A Study to Evaluate the Efficacy and Safety of SYHX1901 Tablet in Non-segmental Vitiligo Patients (NCT06511739) | CSPC Ouyi Pharmaceutical Co., Ltd. | 2024-05-27 |
| Surufatinib Combined With Carboplatin/Paclitaxel and Surufatinib Combined With Olaparib as First-line and Maintenance Therapy for Newly Diagnosed High-risk Ovarian Cancer (NCT06437353) | Anhui Provincial Cancer Hospital | 2024-05-25 |
| Linperlisib Combined With Chidamide in Patients With PTCL (NCT06421948) | Yanyan Liu | 2024-05-25 |
| Durvalumab Combined With S-1 as Adjuvant Therapy of Resectable BTC (NCT06490107) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2024-05-24 |
| Immunotherapy Rechallenge in Patients with Solid Tumors in Clinical Trials (NCT06612632) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2024-05-24 |
| Phase II Trial of Individualized Immunotherapy in Early-Stage Unfavorable Classical Hodgkin Lymphoma (NCT04837859) | University of Cologne | 2024-05-24 |
| Umbilical-Cord-Derived Mesenchymal Stem Cells Injection for Chronic Radiation Proctitis (NCT06438809) | Jiangsu Topcel-KH Pharmaceutical Co., Ltd. | 2024-05-24 |
| Neoadjuvant Adebrelimab + DOS in Locally Advanced Resectable Gastric Cancer (NCT06475417) | Tang-Du Hospital | 2024-05-24 |
| Efficacy of Dihydroartemisinin for Treating PCOS (NCT06417099) | Shanghai Zhongshan Hospital | 2024-05-24 |
| A Multicenter, Prospective, Phase II Study of Zanubrutinib for Maintenance in Patients With Mantle Cell Lymphoma (NCT06341556) | Fudan University | 2024-05-24 |
| Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors (NCT06445062) | Revolution Medicines, Inc. | 2024-05-24 |
| A Phase 2, Dose Ranging Study Assessing Rocatinlimab in Moderate-to-severe Asthma (NCT06376045) | Amgen | 2024-05-24 |
| Fruquintinib With or Without HAI-FOLFOX for Refractory Colorectal Cancer (NCT06441565) | Sun Yat-sen University | 2024-05-24 |
| CBD for Pain Following Orthopedic Shoulder Surgery (NCT06381791) | The Methodist Hospital Research Institute | 2024-05-24 |
| A Study to Investigate Treatment of HU and VPA, or 6-MP and VPA in Unfit AML/HR-MDS Patients (NCT06199557) | Haukeland University Hospital | 2024-05-23 |
| Safety and Efficacy of Stem Cell Small Extracellular Vesicles in Patients With Retinitis Pigmentosa (NCT06242379) | Mahidol University | 2024-05-23 |
| A Study to Find the Dose and Assess the Immune Response and Safety of a Vaccine Against Influenza in Healthy Younger and Older Adults (NCT06431607) | GlaxoSmithKline | 2024-05-23 |
| Different Levels of BiPAP (NCT06421519) | King's College Hospital NHS Trust | 2024-05-23 |
| Golimumab and Apalutamide for the Treatment of Castration-Resistant Prostate Cancer, TRAMP Study (NCT05960578) | University of Washington | 2024-05-23 |
| Evaluating Tetrahydrocannabinol as an Adjunct to Opioid Agonist Therapy (NCT05985850) | BC Centre on Substance Use | 2024-05-23 |
| A Study of Trilaciclib Combined With Chemotherapy in the Treatment of Diffuse Large B-Cell Lymphoma Patients (NCT06569485) | Sun Yat-sen University | 2024-05-23 |
| A Study of GQ1010 in Subjects With Advanced Solid Tumors (NCT06464055) | GeneQuantum Healthcare (Suzhou) Co., Ltd. | 2024-05-23 |
| A Phase I/IIa，Open-label, Single Ascending Dose and Dose-expansion Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of YOLT-201 in Patients With Transthyretin Amyloidosis Polyneuropathy (ATTR-PN) or Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM) (NCT06539208) | YolTech Therapeutics Co., Ltd | 2024-05-23 |
| A Study About Modified RNA Vaccines Against Influenza in Healthy Adults (NCT06436703) | Pfizer | 2024-05-23 |
| A Study of PET/CT Imaging Using INR101 Injection in Healthy Male Subjects and Patients With Suspected Prostate Cancer (NCT06472531) | Yunhe Pharmaceutical (Tianjin) Co., Ltd | 2024-05-23 |
| Efficacy and Safety of Frontline Tislelizumab in Patients With de Novo Hodgkin Lymphoma Unsuitable for Standard Frontline Chemotherapy (NCT05977673) | Fondazione Italiana Linfomi - ETS | 2024-05-23 |
| A Dose Finding Study of Debio 4228 in Participants With Advanced Prostate Cancer (NCT06395753) | Debiopharm International SA | 2024-05-23 |
| A Study Assessing the Efficacy and Safety of HS-10380 in Hospitalized Adults With Acute Schizophrenia (NCT07550387) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2024-05-23 |
| A Phase 2 Study of ZL-1102 in Patients With Chronic Plaque Psoriasis (NCT06380907) | Zai Lab (Hong Kong), Ltd. | 2024-05-22 |
| Study of Serplulimab Plus Chemotherapy as Neoadjuvant Therapy for Limited-stage Small Cell Lung Cancer (LS-SCLC) (NCT06911606) | Guangdong Provincial People's Hospital | 2024-05-22 |
| Sorafenib Relapase Prophylaxis After HCT With PTBCy Regimen (NCT06532084) | St. Petersburg State Pavlov Medical University | 2024-05-22 |
| A Phase II Study of Surufatinib Combined With Camrelizumab and mFOLFOX6 as Second-line Treatment for Advanced PRAD (NCT06329947) | Rui-hua Xu, MD, PhD | 2024-05-22 |
| Treatment of Pulmonary SUlcus, Pancoast and Chest Wall Non-small Cell Lung Cancer Employing Radiation, Immuno-oncology and Resection (NCT06331455) | Marc de Perrot | 2024-05-22 |
| Peginterferon Lambda and Lonafarnib Boosted With Ritonavir 48-Week Combination Therapy for Delta Hepatitis (NCT05953545) | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 2024-05-22 |
| A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence (NCT06336291) | Philogen S.p.A. | 2024-05-22 |
| Perioperative Treatment of Resectable Adenocarcinoma of Esophagogastric Junction by Immunotherapy (Adebrelimab) Combined With Chemotherapy (XELOX): a Prospective, Single-center, Feasibility Study (NCT06482788) | Ruijin Hospital | 2024-05-22 |
| Evaluation of DASATINIB Monotherapy Efficacy in Acute Myeloid Leukemia Patients Refractory to VENETOCLAX-AZACITIDINE (NCT06055621) | Institut Paoli-Calmettes | 2024-05-22 |
| Irinotecan Liposomes in Combination With Nituzumab for the Treatment of Recurrent/Metastatic Nasopharyngeal Carcinoma After Failure of First-Line or Higher Immunotherapy (NCT06414577) | XIANG YANQUN | 2024-05-22 |
| Elimination of PTV Margins Based on Online Adaptive Stereotactic Radiotherapy for Early-stage Non-small Cell Lung Cancer or Pulmonary Oligometastases (NCT06542159) | Sun Yat-sen University | 2024-05-22 |
| WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma (NCT05879250) | Northwestern University | 2024-05-22 |
| Advancing Transplantation Outcomes in Children (NCT06055608) | National Institute of Allergy and Infectious Diseases (NIAID) | 2024-05-22 |
| A Phase I/II Study of Gilteritinib and Momelotinib for Patients With Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia (NCT06235801) | M.D. Anderson Cancer Center | 2024-05-22 |
| Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors (NCT06320405) | OHSU Knight Cancer Institute | 2024-05-21 |
| HIP Fracture Oral ThromboPROphylaxis (Hip PRO Pilot) (NCT05775965) | University of Calgary | 2024-05-21 |
| A Study of Emapalumab for Pediatric Aplastic Anemia (NCT06430788) | Memorial Sloan Kettering Cancer Center | 2024-05-21 |
| Testing the Combination of Two Anticancer Drugs M1774 (Tuvusertib) and Avelumab to Evaluate Their Safety and Effectiveness in Treating Merkel Cell Skin Cancer, MATRiX Trial (NCT05947500) | National Cancer Institute (NCI) | 2024-05-21 |
| Nicotinamide Supplementation Improves Physical Performance in Older Adults at Risk of Falls (NCT06465602) | University of Chile | 2024-05-21 |
| Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study (NCT06039371) | University of Washington | 2024-05-21 |
| Efficacy Study of Blinatumomab Clean Up Early Residual Disease for Newly Diagnosed Pediatric B Lymphoblastic Leukemia (NCT06607419) | Shanghai Jiao Tong University School of Medicine | 2024-05-21 |
| Efficacy and Safety of Apitegromab for the Treatment of Adults Who Are Overweight or Obese (NCT06445075) | Scholar Rock, Inc. | 2024-05-21 |
| Tocilizumab for Painful Chronic Pancreatitis (NCT06426160) | Soren Schou Olesen | 2024-05-21 |
| Safety, Tolerability, and Effectiveness of Intramuscular Injection of CELZ-201-DDT for the Treatment of Chronic Lower Back Pain (NCT06053242) | Creative Medical Technology Holdings Inc | 2024-05-21 |
| Psilocybin for Hospitalized Patients with Treatment-resistant Depression (NCT06378229) | University Hospital, Ghent | 2024-05-21 |
| Effects of NNC0194-0499, Cagrilintide, and Semaglutide Alone or in Combinations on Liver Damage and Alcohol Use in People With Alcohol-related Liver Disease (NCT06409130) | Novo Nordisk A/S | 2024-05-20 |
| Efficacy and Safety of Emodepside in Adults Infected With Strongyloidiasis Stercoralis (NCT06373835) | Swiss Tropical & Public Health Institute | 2024-05-20 |
| Study That Tests AD109 in Patients Taking GLP-1 Drugs (NCT06400615) | Apnimed | 2024-05-20 |
| PeRampanel fOr Status ePilEpticus pRophylaxis Post-cardiac Arrest (NCT06401707) | University of California, San Francisco | 2024-05-20 |
| Sequential Tegafur-gimeracil-oteracil Potassium Capsule (s-1) and Serplulimab Following Concurrent Chemoradiotherapy for Esophageal Squamous Cell Carcinoma (NCT06422858) | Zhejiang Cancer Hospital | 2024-05-20 |
| Safety and Efficacy of CAR T Cell Therapy in Patients with R/r B-ALL (NCT06635330) | Kara Yakhteh Tajhiz Azma Company | 2024-05-20 |
| Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A) (NCT06353386) | Merck Sharp & Dohme LLC | 2024-05-20 |
| A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors (NCT06157892) | Seagen, a wholly owned subsidiary of Pfizer | 2024-05-20 |
| This is a Phase II, Open-label, Multicentre Study of Zanubrutinib-containing Regimens in Patients With Newly Diagnosed Mantle Cell Lymphoma (NCT06427213) | Henan Cancer Hospital | 2024-05-20 |
| Sintilimab, Pegaspargase Plus GemOx for Untreated Extranodal NK/T-Cell Lymphoma (NCT06824883) | Peking Union Medical College Hospital | 2024-05-20 |
| Dasatinib Combined With Quercetin to Reverse Chemo Resistance in Triple Negative Breast Cancer (NCT06355037) | Fudan University | 2024-05-20 |
| Passive Stretching in Peripheral Arterial Disease Patients (NCT06420752) | University of Wisconsin, La Crosse | 2024-05-20 |
| Combination Cefazolin With Ertapenem for Methicillin-susceptible Staphylococcus Aureus Bacteremia (NCT04886284) | Todd C. Lee MD MPH FIDSA | 2024-05-20 |
| The Phoenix Trial: Phase II Trial of Cemiplimab for the Non-operative Management of Localized dMMR Colon Cancer (NCT05961709) | M.D. Anderson Cancer Center | 2024-05-20 |
| Proton Therapy for Locally Advanced Cervical Cancer (NCT06462378) | University of Aarhus | 2024-05-20 |
| A Study of TAK-853 in Adult Participants With Folate Receptor Alpha-Positive Advanced Ovarian Cancer And Other Solid Tumors (NCT06390995) | Takeda | 2024-05-20 |
| A 16-Week Study to Evaluate the Efficacy, Safety, and Tolerability of GLY-200 in Participants With Obesity (NCT06259981) | Glyscend, Inc. | 2024-05-20 |
| A Study Comparing Neoadjuvant Chemoimmunotherapy and Immuno-consolidationafter Compared With Immunoconsolidation After Radical Chemoradiotherapy for Stage III Potentially Resectable NSCLC (NCT06424899) | Zeng Jian | 2024-05-19 |
| A Study of Paclitaxel Combined With Apatinib and Adebrelimab in Gastric/Gastroesophageal Junction Adenocarcinoma (NCT06415669) | The First Affiliated Hospital of Xiamen University | 2024-05-19 |
| Neoadjuvant and Adjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma (NCT06295159) | H. Lee Moffitt Cancer Center and Research Institute | 2024-05-17 |