| A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of Oral SAL0137 in Adults With Elevated Lp(a) and Increased Risk of Cardiovascular Events (NCT07729475) | Shenzhen Salubris Pharmaceuticals Co., Ltd. | 2026-07-27 |
| A Phase 2, Open-Label, Single-Arm Trial of FT819 in Participants With Lupus Nephritis (NCT07570862) | Fate Therapeutics | 2026-07-27 |
| 9-cis Beta-Carotene-Rich Extract of Dunaliella Alga in Retinitis Pigmentosa Patients (NCT07509229) | Sheba Medical Center | 2026-07-26 |
| Hypofractionated Radiotherapy Plus GM-CSF, Pomalidomide and Glofitamab for Newly Diagnosed PCNS-DLBCL (NCT07749365) | The First Affiliated Hospital of Xiamen University | 2026-07-25 |
| Whole Versus Partial Gland Boost During Prostate SBRT (NCT07574489) | University of Nebraska | 2026-07-25 |
| The BANYAN Trial, an ALS MyMatch Trial Evaluating Safety, Biomarker Activity, and Microglial Activation of Nasal Foralumab (NCT07688239) | Tiziana Life Sciences LTD | 2026-07-25 |
| Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis (NCT07697456) | AbbVie | 2026-07-24 |
| Phase 1/2 Study of OPK-88006 in Healthy and Presumed MASH Participants (NCT07512427) | OPKO Health, Inc. | 2026-07-24 |
| A Study of BL-B01D1 in Combination With Osimertinib as Perioperative Therapy in Patients With EGFR-mutated Resectable Non-small Cell Lung Cancer(PANKU-Lung09) (NCT07642024) | Sichuan Baili Pharmaceutical Co., Ltd. | 2026-07-24 |
| Motixafortide for MRD Sensitization in AML (NCT07392970) | Washington University School of Medicine | 2026-07-23 |
| Induced Suppression of Platelet Activity in Aneurysmal Subarachnoid Hemorrhage Management-2 (iSPASM-2) (NCT07493577) | Dr David Hasan, M.D. | 2026-07-23 |
| Vorasidenib Study in Pediatric Participants With Grade 2 Astrocytoma or Oligodendroglioma With an IDH1 or IDH2 Mutation (NCT07286292) | Institut de Recherches Internationales Servier (I.R.I.S.) | 2026-07-23 |
| REGN22530 for Adults With Primary Open Angle Glaucoma or Ocular Hypertension (NCT07675824) | Regeneron Pharmaceuticals | 2026-07-23 |
| Impact of Minimally Invasive Endodontic Treatment on the Prognosis of Mandibular Permanent Molars With Necrotic Pulp and Apical Periodontitis (NCT07762248) | Mohamed Ashraf Abdeen | 2026-07-23 |
| A Study of IMM2510 + IMM27M Combination Therapy in Patients With Advanced Hepatocellular Carcinoma (NCT07687914) | ImmuneOnco Biopharmaceuticals (Shanghai) Inc. | 2026-07-23 |
| EGFR-ADC (Becotatug Vedotin) Combined With PD-1 Inhibitor (Pucotenlimab) in Neoadjuvant Treatment of Advanced Penile Cancer (NCT07518979) | Jiyan Liu | 2026-07-22 |
| Efficacy and Safety of Ascending Doses of Arpraziquantel in Children Infected With Opisthorchis Viverrini (NCT07262814) | Jennifer Keiser | 2026-07-22 |
| A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Non-Small Cell Lung Cancer (NCT07659782) | Verastem, Inc. | 2026-07-22 |
| A Study of Glofitamab Plus GemOx Compared With Standard of Care in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (NCT07599423) | The First Affiliated Hospital of Soochow University | 2026-07-22 |
| Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older (NCT07734649) | Sanofi | 2026-07-22 |
| Efficacy and Safety of Retlirafusp Alfa Plus Bevacizumab and Chemotherapy With or Without Short-Course Radiotherapy in Patients With CRCLM (NCT07728019) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2026-07-22 |
| Maintenance Immunotherapy With Deferred Salvage Radiotherapy After Response to Chemoimmunotherapy in Recurrent Nasopharyngeal Carcinoma (NCT07528183) | Sun Yat-sen University | 2026-07-22 |
| Low-dose Thoracic Radiotherapy Followed by Adebrelimab Plus Chemotherapy, and Then Sequential Maintenance Therapy With Adebrelimab for Extensive-stage Small Cell Lung Cancer (NCT07583550) | Jiangmen Central Hospital | 2026-07-21 |
| Autologous Serum Tears With Hyaluronate vs Balanced Salt Solution for Moderate-to-Severe Dry Eye (NCT07413172) | University of Miami | 2026-07-21 |
| DReAMzz- Dronabinol and Acetazolamide Medication for Sleep Apnea (ZZ). Dose Confirmation Crossover Study for IHL-42X in Subjects With Obstructive Sleep Apnea. (NCT07635563) | Incannex Healthcare Ltd | 2026-07-21 |
| Setmelanotide to Treat Obesity in a Patient With Pseudohypoparathyroidism Type 1a (PHP1a) (NCT07496463) | Massachusetts General Hospital | 2026-07-21 |
| Assessment of the Long-term Efficacy of Moderately Hypofractionated Neoadjuvant Radiotherapy Soft Tissue Sarcoma in the Limbs or Trunk Wall (NCT07507773) | Centre Oscar Lambret | 2026-07-21 |
| Effect of Melatonin Administration on Systemic Lupus Erythematosus Patients (NCT07721324) | Ain Shams University | 2026-07-21 |
| BCMA/GPRC5D Trispecific Antibody Treatment for Newly Diagnosed Amyloidosis (AL-004) (NCT07751471) | Institute of Hematology & Blood Diseases Hospital, China | 2026-07-20 |
| Strategic Endocrine Therapy and Targeted Radiotherapy for Prostate Cancer (NCT07364071) | University of California, San Diego | 2026-07-20 |
| Phase Ib/II Multicenter Randomized Control Study of Peri-operative Treatment With Combination of CTLA-4, PD-1 Antibodies and Bevacizumab in Resectable HCC (Prophet) (NCT07714317) | Shanghai Zhongshan Hospital | 2026-07-20 |
| Phase 1/2 Study of FRF-001, an AAV-9 Gene Therapy, in Patients With FOXG1 Syndrome (FS) (NCT07293546) | FOXG1 Research Foundation | 2026-07-20 |
| Colchicine to Reduce Your SympToms And Lower Levels of Inflammation, Zeroing in on Effective CPPD Disease Treatment (NCT06855433) | Brigham and Women's Hospital | 2026-07-20 |
| Becotatugvedotin Plus Pucotenlimab in EGFR-Positive Advanced Gastric/GEJ Adenocarcinoma (NCT07692334) | West China Second University Hospital | 2026-07-20 |
| REGN15505 (PSMAx4-1BB) Alone or in Combination With Cemiplimab or REGN4336 (PSMAxCD3) in Adult Patients With Metastatic Castration-Resistant Prostate Cancer and Clear Cell Renal Cell Carcinoma (NCT07594106) | Regeneron Pharmaceuticals | 2026-07-20 |
| A Clinical Study of V540A in Healthy Female Participants (V540A-005) (NCT07224477) | Merck Sharp & Dohme LLC | 2026-07-20 |
| A Clinical Trial to Evaluate the Efficacy and Safety of HRS-9821 Inhalation Suspension in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (NCT07640451) | Guangdong Hengrui Pharmaceutical Co., Ltd | 2026-07-20 |
| PfSPZ-LARC2 Vaccine in Women of Child-bearing Potential (WOCBP) in Mali (NCT07675785) | Sanaria Inc. | 2026-07-20 |
| Combatting HIV Or Other STIs Early (CHOOSE) (NCT07510048) | Westat | 2026-07-20 |
| Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young Adults With Anorexia Nervosa (NCT07169747) | Region Skane | 2026-07-20 |
| A Clinical Trial Comparing the Efficacy and Safety of Different Doses of BL0175 Injection in Treating Postmenopausal Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Locally Advanced or Metastatic Breast Cancer (NCT07658183) | Shanghai Best-Link Bioscience, LLC | 2026-07-20 |
| Sintilimab Monotherapy in Patients With Stage I-II MSI-H/dMMR Endometrial Cancer (NCT07731607) | Wang Jianliu | 2026-07-20 |
| QL1706（Iparomlimab/Tuvonralimab) Combined With Gemcitabine and Cisplatin as First-Line Treatment for PD-L1-Positive Biliary Tract Cancer (NCT07733115) | Shanghai Zhongshan Hospital | 2026-07-20 |
| A Study of Luspatercept in People With Anemia (NCT07725497) | Memorial Sloan Kettering Cancer Center | 2026-07-20 |
| Platform Research for Innovative Medicines in NF2-SWN (PRIME-NF2) (NCT07713745) | Beijing Tiantan Hospital | 2026-07-18 |
| Venetoclax or Placebo in Combination With Reduced-Intensity Conditioning Hematopoietic Cell (Bone Marrow/Blood Stem Cell) Transplant and as Maintenance Therapy After Transplant in Patients With Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial) (NCT06954987) | National Cancer Institute (NCI) | 2026-07-17 |
| Phase IIb Clinical Trial to Evaluate the Efficacy and Safety of VG081821AC Tablets in Patients With Early to Mid-stage Parkinson's Disease (NCT07725562) | Zhejiang Vimgreen Pharmaceuticals, Ltd. | 2026-07-17 |
| Eating Disorder Chatbot Optimization (NCT07218302) | Washington University School of Medicine | 2026-07-17 |
| A Phase II Study of AK146D1 Combined With AK112 in Advanced Breast Cancer (NCT07591090) | Akeso | 2026-07-17 |
| A Multicenter, Open-label, Randomized, Prospective Clinical Study of Adebrelimab Consolidation Therapy for Limited-Stage Small-Cell Lung Cancer (LS-SCLC) Without Progression After Concurrent Chemoradiotherapy (NCT07559786) | Henan Cancer Hospital | 2026-07-17 |
| SSGJ-705 Plus SSGJ-612 ± Chemotherapy in Advanced HER2-Expressing Solid Tumors (NCT07646626) | Shenyang Sunshine Pharmaceutical Co., LTD. | 2026-07-17 |
| Neoadjuvant SHR-A1811 and SHR-A1701 ± Pertuzumab for Potentially Immunotherapy-Sensitive GC or GEJ Adenocarcinoma (NCT07716111) | The First Affiliated Hospital with Nanjing Medical University | 2026-07-16 |
| Preoperative Use of Romiplostim in Thrombocytopenic Patients Undergoing Cardiac Surgery. (NCT07278661) | Nantes University Hospital | 2026-07-16 |
| A Clinical Trial of TQH3906 Capsules in the Treatment of Active Psoriatic Arthritis (NCT07406035) | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | 2026-07-16 |
| A Clinical Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) in Patients With Severe Asthma (NCT07532265) | Kinaset Therapeutics Inc | 2026-07-16 |
| A Study of JZP3507 (ONC206) in Recurrent Grade 2 or 3 Meningioma (NCT07533942) | Jazz Pharmaceuticals | 2026-07-16 |
| Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT) (NCT07569198) | Joshua Rosenblat | 2026-07-16 |
| SMP-656 for HER2-Positive Advanced Breast Cancer (NCT07726342) | Chengdu SciMount Pharmatech Co., Ltd. | 2026-07-16 |
| Becotatug Vedotin Combined With Pucotenlimab ± Radiotherapy as First-Line Treatment for Driver-Gene-Negative, EGFR-Expression-Positive Advanced Non-Small Cell Lung Cancer (NCT07627321) | Anhui Provincial Cancer Hospital | 2026-07-15 |
| Natrunix in Combination With Methotrexate for Rheumatoid Arthritis Treatment (NCT06590090) | XBiotech, Inc. | 2026-07-15 |
| Intrathecal Gene Therapy For SLC13A5 Citrate Transporter Disorder (NCT07102524) | TESS Research Foundation | 2026-07-15 |
| Therapeutic Approach of Repeated Transient Blood-brain Barrier Opening in Amyotrophic Lateral Sclerosis. (NCT07571486) | Assistance Publique - Hôpitaux de Paris | 2026-07-15 |
| Efficacy of Tezepelumab in Peanut Oral Immunotherapy (NCT07015996) | National Institute of Allergy and Infectious Diseases (NIAID) | 2026-07-15 |
| the Effect of Ginkgo Biloba on Rheumatoid Arthritis Patients (NCT07709312) | Ain Shams University | 2026-07-15 |
| A Study of Zasocitinib (TAK-279) in Adults With Active Crohn's Disease (NCT07403968) | Takeda | 2026-07-15 |
| Domatinostat With Sirolimus for Relapsed, Refractory Sarcoma and Osteosarcoma (NCT07725380) | H. Lee Moffitt Cancer Center and Research Institute | 2026-07-15 |
| Sintilimab Plus Gossypol Acetate in Advanced Colorectal Cancer (NCT07656766) | Peking University People's Hospital | 2026-07-15 |
| Caffeine Optimization for Oxygen Saturation Index in ELBW Infants (NCT07216365) | University of Rochester | 2026-07-15 |
| Orelabrutinib Combined With Obinutuzumab and Short-Course Venetoclax in Patients With Treatment-Naïve Mantle Cell Lymphoma (MCL) (NCT07719556) | The First Affiliated Hospital with Nanjing Medical University | 2026-07-15 |
| Yang et al. Anti-PD-1/CTLA-4 Dual Immunotherapy for LARC (NCT07596290) | Beijing Friendship Hospital | 2026-07-15 |
| Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Carcinomas (NCT06202066) | Roswell Park Cancer Institute | 2026-07-15 |
| Riptylimab for the Treatment of Optic Neuritis and Myelitis Spectrum Diseases (NCT07685678) | Zhongming Qiu | 2026-07-15 |
| A Phase Ib/IIa Study Assessing the Rapid Onset Characteristics of TLL-018 for Moderate-to-Severe CSU With Inadequate Response to Second-Generation H1 Antihistamines (NCT07665996) | Hangzhou Highlightll Pharmaceutical Co., Ltd | 2026-07-15 |
| Regenerative Medicine for Joint Hypermobility and Instability (NCT07688096) | Manhattan Pain Medicine, PLLC | 2026-07-15 |
| Low-Dose Radiotherapy for Alzheimer's Disease (NCT07693140) | Evan Thomas | 2026-07-15 |
| Epcoritamab in Combination With R-CHOP for Patients With Aggressive Non-Hodgkin Lymphoma (NCT07588698) | Mwanasha Merrill, MD | 2026-07-15 |
| The PROTECT-HIE Pilot Trial (NCT07406477) | University of Alberta | 2026-07-15 |
| A Trial of CRD-4730 in HFrEF (NCT07750873) | Cardurion Pharmaceuticals, Inc. | 2026-07-15 |
| Impact of Sotatercept on Pulmonary Artery and Right Ventricle Remodeling Imaging Assessed With 68Ga-FAPI PET/CT in Patients With PAH (NCT07357974) | University Hospital, Brest | 2026-07-15 |
| A Phase II Trial for MOR Antagonism With Axelopran to Enhance Immunotherapy in Head and Neck Cancer (NCT07662720) | Glycyx Therapeutics | 2026-07-15 |
| SBRT Followed by Ipilimumab N01, Sintilimab, Nab-Paclitaxel and Gemcitabine for Locally Advanced Pancreatic Cancer (NCT07683221) | Shandong Cancer Hospital and Institute | 2026-07-15 |
| An Exploratory Study of Obinutuzumab β in the Treatment of Chronic Inflammatory Demyelinating Polyradiculoneuropathy (NCT07696377) | Zhongming Qiu | 2026-07-15 |
| A Study of Daily Rifapentine Combined With Isoniazid (1HP) for Tuberculosis Prevention in Children Less Than 13 Years of Age With and Without HIV (NCT07124559) | National Institute of Allergy and Infectious Diseases (NIAID) | 2026-07-15 |
| Fosrolapitant and Palonosetron for the Prevention of Antibody-drug Conjugate-induced Nausea and Vomiting (NCT07692451) | Peking University Cancer Hospital & Institute | 2026-07-15 |
| A Clinical Study Evaluating a New Treatment Strategy for Patients With Advanced Pancreatic Cancer Who Have Not Received Prior Treatment for Advanced Disease. (NCT07578337) | Nelum Corp | 2026-07-15 |
| Study to Evaluate ALN-CIDEB in Adults With Fibrotic Metabolic Dysfunction-Associated Steatohepatitis (MASH) (NCT07631637) | Regeneron Pharmaceuticals | 2026-07-15 |
| Age-Stratified Conditioning Regimen Efficacy for MDS Haplo-HSCT (NCT07677306) | Peking University People's Hospital | 2026-07-15 |
| Evaluation of the O'Neil Long Acting Naltrexone Implant in Opioid Dependent Persons (NCT05382091) | Go Medical Industries Pty Ltd | 2026-07-15 |
| Fosamprenavir for Laryngopharyngeal Upper Airway Tissue Treatment and Enzyme Reduction (NCT04383262) | Medical College of Wisconsin | 2026-07-15 |
| Efficacy of Methylene Blue Photodynamic Therapy for Treatment of Deep Tissue Abscesses (NCT06052956) | University of Rochester | 2026-07-15 |
| A Multi-Center, Individually-Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Superiority Trial to Evaluate the Efficacy of the Combination of Maraviroc and Atorvastatin for the Treatment of Subjects With Long COVID (NCT06974084) | HealthBio, Inc. | 2026-07-15 |
| A Study of SYH2070 Injection in Participants With Mixed Hyperlipidemia (NCT07695597) | CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. | 2026-07-15 |
| Multi Interventional Approaches to Mitigate HIV Reservoirs for the Sustained HIV Remission Without Antiretrovirals (NCT06805656) | Federal University of São Paulo | 2026-07-15 |
| A Phase Ib/II Study of HDM2017 in Combination With Standard of Care in Advanced Colorectal Cancer (NCT07621159) | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | 2026-07-15 |
| Evaluation of [68Ga]Ga-NOTA-anti-HER2-sdAb PET/CT for Predicting Pathological Complete Response After Neoadjuvant Chemotherapy in HER2 Positive Early Breast Cancer (NCT07593976) | Centre Henri Becquerel | 2026-07-15 |
| Superoxide Dismutase Skin Spray for the Prevention of Acute Radiation Dermatitis in Head and Neck Cancer (NCT07704372) | West China Hospital | 2026-07-15 |
| Sacituzumab Tirumotecan vs MMAE-ADCs in Advanced Urothelial Carcinoma (FUSCC-SPARE-UC-01) (NCT07662863) | Fudan University | 2026-07-15 |
| Selumetinib for NF2-Related Schwannomatosis (NCT07707947) | Beijing Tiantan Hospital | 2026-07-15 |
| Perioperative HLX10 (Serplulimab) With S-1+Oxaliplatin (SOX) in Locally Advanced and PD-L1-Positive Gastric or Esophagogastric Junction Adenocarcinoma (NCT07699939) | National Cancer Center, Japan | 2026-07-15 |
| Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma (NCT07416188) | National Institute of Neurological Disorders and Stroke (NINDS) | 2026-07-15 |