| The Proposed Study Aims to Investigate the Efficacy of Quercetin as an Adjunctive to Mechanical Debridement in Treatment of Periodontitis (NCT06982248) | Mansoura University | 2024-08-15 |
| Pemigatinib and Immune Checkpoint Inhibitor Treated FGFR1/2/3 Alteration Advanced Solid Tumor (NCT06551896) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2024-08-15 |
| Elimination of Prostate Cancer Treatment Side Effects Using a Nutraceutical (NCT06643494) | Optimal Health Research | 2024-08-15 |
| Food-Body-Mind Intervention (16 Weeks) (NCT06597474) | Michigan State University | 2024-08-14 |
| SMP-3124LP in Adults With Advanced Solid Tumors (NCT06526819) | Sumitomo Pharma America, Inc. | 2024-08-14 |
| A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor. (NCT06247995) | Novartis Pharmaceuticals | 2024-08-14 |
| A Study of ZT002 Injection With Subjects With Overweight or Obesity (NCT07020884) | Beijing QL Biopharmaceutical Co.,Ltd | 2024-08-14 |
| A Study to Assess Molecular Changes in Adult Participants With Moderate to Severe Hidradenitis Suppurativa or With Moderate to Severe Atopic Dermatitis Receiving Subcutaneous Injections of Lutikizumab (NCT06524635) | AbbVie | 2024-08-14 |
| Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (SCCis) (NCT06577311) | The Center for Clinical and Cosmetic Research | 2024-08-14 |
| TumorGlow Intraoperative Molecular Imaging (IMI) (NCT04723810) | University of Pennsylvania | 2024-08-14 |
| Adebrelimab Plus Chemo and Recaticimab in Perioperative Treatment of Resectable NSCLC (NCT06467617) | Beijing Chest Hospital, Capital Medical University | 2024-08-14 |
| Acetazolamide in Persons With Type 1 Diabetes - Crossover Trial (NCT06981234) | University of California, San Diego | 2024-08-14 |
| A Study to Evaluate Solrikitug in Participants With COPD (ZION) (NCT06496620) | Uniquity One (UNI) | 2024-08-14 |
| A Study Evaluating the Safety, Tolerability, and Efficacy of EVO756 in Adults With Chronic Inducible Urticaria (NCT06603220) | Evommune, Inc. | 2024-08-14 |
| Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer (NCT06409390) | H. Lee Moffitt Cancer Center and Research Institute | 2024-08-14 |
| Working Out M0 Bipolar Androgen Therapy (NCT06594926) | Australian and New Zealand Urogenital and Prostate Cancer Trials Group | 2024-08-14 |
| Use of a Cannabinoids as a Treatment Strategy for Alzheimer's Disease (NCT06570928) | Federal University of Latin American Integration | 2024-08-13 |
| Ritlecitinib in Patients With Keloids or Those Undergoing Keloidectomy (NCT06373458) | Icahn School of Medicine at Mount Sinai | 2024-08-13 |
| A Study to Investigate Natural Killer Cell Engager (SAR443579) With Different Agents in Participants With Hematological Malignancies (NCT06508489) | Sanofi | 2024-08-13 |
| Efficacy and Safety of Ribociclib Combined With AI Versus Physician&Amp;#39;s Choice of Chemotherapy Sequential Endocrine Therapy in ER Middle-low-expression/HER2-negative Advanced Breast Cancer (Rachel) (NCT06656624) | The First Affiliated Hospital with Nanjing Medical University | 2024-08-13 |
| MSC EVs in Dystrophic Epidermolysis Bullosa (NCT04173650) | Aegle Therapeutics | 2024-08-13 |
| Evaluate the Safety and Efficacy of CPX101 in Overweight and Obese Subjects Without Diabetes Mellitus (NCT06532578) | Guangzhou Chia Tai Innovative Pharmaceutical Co., Ltd. | 2024-08-13 |
| Correcting Circadian Rhythms to Breakthrough in Bipolar Disorder (NCT06226025) | Leslie Swanson | 2024-08-13 |
| MR-guided Adaptive Radiotherapy Combined With PD-1 Antibody and CAPOX for Locally Advanced Rectal Cancer (NCT06840665) | Fudan University | 2024-08-13 |
| Chiauranib in Patients With Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma (NCT06492915) | Chipscreen Biosciences, Ltd. | 2024-08-13 |
| Linperlisib Combination With Obinutuzumab Frontline Treatment of Marginal Zone Lymphoma Patients (MZL) (NCT06592170) | The First Hospital of Jilin University | 2024-08-13 |
| Phase II Clinical Study of Adebrelimab Combined with Apatinib in the Treatment of Locally Advanced Non-small Cell Lung Cancer Patients with Radiation Pneumonitis (NCT06700421) | Wei Zhou | 2024-08-13 |
| Comparison of the Effect of Red Wine With Alcohol on Flow-mediated Dilation Versus Red Wine Without Alcohol (NCT06535620) | Instituto de Cardiologia de Santa Catarina | 2024-08-13 |
| Treatment of Newly Diagnosed Central Malignant Germ Cell Tumor People With Teniposide Injection Combined With Cisplatin. (NCT07188441) | Chengcheng Guo | 2024-08-13 |
| The PLATINUM Trial: Optimizing Chemotherapy for the Second-Line Treatment of Metastatic BRCA1/2 or PALB2-Associated Metastatic Pancreatic Cancer (NCT06115499) | Alliance for Clinical Trials in Oncology | 2024-08-13 |
| A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed/Refractory Hematologic Malignancies (NCT06492304) | CRISPR Therapeutics | 2024-08-13 |
| Patritumab Deruxtecan in Patients With Solid Tumor Harboring an NRG1 Fusion (NCT06383884) | Samsung Medical Center | 2024-08-13 |
| Carboplatin/Paclitaxel + Pembrolizumab for Locoregionally Advanced Penile Cancer (NCT06353906) | The Netherlands Cancer Institute | 2024-08-13 |
| Methotrexate for Immune Related Arthritis or Arthralgias (IMPACT 2.1) (NCT06001125) | AHS Cancer Control Alberta | 2024-08-12 |
| Exploratory Clinical Study of SHR-0302 and SHR-2554 in Patients With Relapsed/Refractory Peripheral T Cell Lymphoma (NCT06519526) | Fudan University | 2024-08-12 |
| Effects of Relugolix vs Leuprolide on Cardiac Function in Patients With Prostate Cancer (NCT06330805) | Ohio State University Comprehensive Cancer Center | 2024-08-12 |
| Metformin Repurposing in Oral Submucous Fibrosis: Unveiling In Vitro Signaling Pathways, Progressing to Clinical Trial (NCT06332612) | Ziauddin University | 2024-08-12 |
| 129 Xenon MRI as a Biomarker for Diagnosis and Response to Therapy in Pulmonary Arterial Hypertension (PAH) (NCT06104228) | Bastiaan Driehuys | 2024-08-12 |
| Mind Matters; Unveiling the Impact of Digital Mental Health Intervention (DMHI) on Psychological Distress Among Youth (NCT06875557) | Fatima Jinnah Women University | 2024-08-12 |
| Phase 2a Study of Safety, Tolerability, and Efficacy of TLC-2716 in Subjects With Hypertriglyceridemia and NAFLD (NCT06564584) | OrsoBio, Inc | 2024-08-12 |
| MB-CART19.1 in Refractory SLE (NCT06189157) | Miltenyi Biomedicine GmbH | 2024-08-12 |
| ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain (NCT06442566) | Medical University of South Carolina | 2024-08-12 |
| Semaglutide in Auto-HSCT (NCT06449625) | Klaus Gottlob Müller | 2024-08-12 |
| A Trial of HRS-6209 in Combination With Fulvestrant, Letrozole, HRS-8080, or HRS-1358 in Breast Cancer Patients (NCT06555068) | Jiangsu HengRui Medicine Co., Ltd. | 2024-08-12 |
| RECOVER-SLEEP: Platform Protocol, Appendix_A (Hypersomnia) (NCT06404099) | Duke University | 2024-08-12 |
| An Investigational Scan (Ga-68 PSMA-11 PET/CT) for the Detection of Therapy Response in Patients With Metastatic Adenoid Cystic Carcinoma (NCT06521775) | Mayo Clinic | 2024-08-12 |
| Thalidomide Enhances Clinical Efficacy of Cetuximab Combined With Standard Chemotherapy for Left Colorectal Cancer (NCT06279351) | Xinqiao Hospital of Chongqing | 2024-08-11 |
| A Trial of HRS-1893 in Patients With Obstructive Hypertrophic Cardiomyopathy (NCT06516068) | Shandong Suncadia Medicine Co., Ltd. | 2024-08-11 |
| Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver Metastases (NCT05588388) | Kamya Sankar | 2024-08-11 |
| Thalidomide for the Symptomatic Large Granular Lymphocytic Leukemia (NCT06530576) | Institute of Hematology & Blood Diseases Hospital, China | 2024-08-10 |
| ERAS Approach for Post-Craniotomy Headache and Psychological Recovery (NCT07510217) | Tanta University | 2024-08-10 |
| Erectile Dysfunction Treatment Using Stem Cells (NCT06550752) | COR clinic of Regenerative Medicine | 2024-08-10 |
| Ketofol Versus Dexmedetomidine for Prevention of Emergence Delirium in Pediatric Patients Undergoing Squint Surgeries (NCT06545890) | Cairo University | 2024-08-10 |
| PI3K Inhibitors for the Treatment of Relapsed/Refractory Indolent T/NK-cell Lymphomas (NCT06530550) | Institute of Hematology & Blood Diseases Hospital, China | 2024-08-10 |
| Neratinib Tablets Monotherapy for Advanced Solid Tumors With HER2 Mutations (NCT06519110) | Convalife (Shanghai) Co., Ltd. | 2024-08-10 |
| Treatment of Newly Diagnosed High Risk Pediatric Acute Lymphoblastic Leukemia (NCT06184009) | Jae Wook Lee | 2024-08-10 |
| Albumin for Patients With Acute Large Vessel Occlusive Stroke Undergoing Endovascular Reperfusion Therapy (NCT06538844) | Capital Medical University | 2024-08-10 |
| Surufatinib Combined With Serplulimab and Standard Chemotherapy as First-line Treatment in Advanced Solid Tumors With Neuroendocrine Differentiation (NCT06531291) | RenJi Hospital | 2024-08-10 |
| A Study of APG-2575 in Patients With Mild-to-moderate Systemic Lupus Erythematosus. (NCT06182969) | Ascentage Pharma Group Inc. | 2024-08-09 |
| Lithium for Parkinson's: an Extension Trial (NCT06592014) | State University of New York at Buffalo | 2024-08-09 |
| ICI Rechallenge for Advanced NSCLC With Long-Term Response to First-Line ICI (NCT06388031) | Peking Union Medical College Hospital | 2024-08-09 |
| A Study to Evaluate the Effect of Venetoclax on Participants Receiving a Covalent Bruton's Tyrosine Kinase Inhibitor (cBTKi) for First-line Chronic Lymphocytic Leukemia (1L CLL) to Achieve Deep Durable Remissions to Allow Off-treatment Period (NCT06524375) | Genentech, Inc. | 2024-08-09 |
| Adding Targeted Drugs to Usual Chemotherapy for Adults With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LBL) (NCT06210750) | National Cancer Institute (NCI) | 2024-08-09 |
| A Study of HRS-4642 in Combination With Antineoplastic Agents in Advanced Solid Tumors (NCT06520488) | Jiangsu HengRui Medicine Co., Ltd. | 2024-08-09 |
| Exploratory Study of Irinotecan Liposomes in Maintenance Therapy of Metastatic Colorectal Cancer (NCT06341309) | West China Hospital | 2024-08-09 |
| Safety and Efficacy of Umbilical Cord-derived Mesenchymal Stem Cell(MSC) Transplantation in the Treatment of Bronchopulmonary Dysplasia(BPD) in Premature Infants (NCT06788470) | The Children's Hospital of Zhejiang University School of Medicine | 2024-08-09 |
| Carbon Ion Radiotherapy for Locally Advanced Lung Cancer in Elderly Patients (NCT06311981) | Jian Chen | 2024-08-08 |
| AGEN1423 and Botensilimab w/ or w/o Chemo in PDAC (NCT05632328) | Bruno Bockorny | 2024-08-08 |
| Phase II Study of REPotrectinib With or Without Fulvestrant in Patients With Hormone Receptor-positive Human Epidermal Growth Factor 2-negative Metastatic Invasive LObular Carcinoma Who Received a Prior Endocrine Therapy in Combination With Cyclin-dependent Kinase 4 and 6 Inhibitor (REPLOT Trial) (NCT06408168) | M.D. Anderson Cancer Center | 2024-08-08 |
| Safety, Pharmacokinetics and Efficacy of MBX 2109 in Patients With Hypoparathyroidism (NCT06465108) | MBX Biosciences | 2024-08-08 |
| Phase 2a Study of VTX3232 in Parkinson's Disease (NCT06556173) | Zomagen Biosciences Ltd. | 2024-08-08 |
| Efficacy and Safety of Intrathecal Administration of Thiotepa in Combination With Methotrexate in Breast Cancer With Leptomeningeal Metastasis (NCT06543992) | The First Affiliated Hospital with Nanjing Medical University | 2024-08-08 |
| Radiotherapy with Immunotherapy and Anti-Angiogenic Therapy for Advanced HER2-Negative Breast Cancer: a Single-Arm Study (NCT06890871) | Zhongnan Hospital | 2024-08-08 |
| SHR-4602 for Injection in Subjects With HER2-expressing or -Mutated Unresectable or Metastatic Solid Tumors (NCT06516926) | Jiangsu HengRui Medicine Co., Ltd. | 2024-08-08 |
| Adbelimumab Combined With Chemotherapy and Apatinib in Patients With Resectable Esophageal Squamous Cell Carcinoma (NCT06576973) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2024-08-08 |
| Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial) (NCT06031688) | SWOG Cancer Research Network | 2024-08-08 |
| Evaluate Efficacy and Safety of Repeat Subcutaneous Doses of FB825 in Adults With Moderate-to-Severe Atopic Dermatitis (NCT06397911) | Oneness Biotech Co., Ltd. | 2024-08-08 |
| A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer (NCT06319963) | Theravectys S.A. | 2024-08-08 |
| E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder (NCT05722561) | NYU Langone Health | 2024-08-08 |
| A Study to Learn About How Well BAY3283142 Works and Its Safety in Participants With Chronic Kidney Disease (NCT06522997) | Bayer | 2024-08-08 |
| The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer (NCT06439693) | Dana-Farber Cancer Institute | 2024-08-08 |
| Clinical Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Intravitreal (IVT) Injection of ABI-110 (AAV2.N54-VEGF Trap) in Subjects With Neovascular (Wet) Age-Related Macular Degeneration (wAMD), Including Symptomatic Macular Polypoidal Choroidal Vasculopathy (PCV) (NCT06550011) | Avirmax Biopharma Inc | 2024-08-07 |
| Contrast Enhanced Ultrasound to Evaluate Response to Chemoembolization in Patients With Liver Tumors (NCT06261814) | john eisenbrey | 2024-08-07 |
| A Phase II Study Bolstering Outcomes by Optimizing Immunotherapy Strategies With Evolocumab and Nivolumab in Patients With Metastatic Renal Cell Carcinoma (BOOST-RCC) (NCT06284564) | M.D. Anderson Cancer Center | 2024-08-07 |
| Polymeric Micellar Paclitaxel-Based Combination Therapy for Advanced Biliary Tract Cancer (NCT07159204) | Peking Union Medical College Hospital | 2024-08-07 |
| BCL-2 Inhibitors Combined with the HyperCVAD Regimen for Newly Diagnosed T-lymphoblastic Leukemia/lymphoma. (NCT06598722) | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 2024-08-07 |
| A Research Study Comparing How Well Different Doses of the Medicine NNC0487-0111 Lower Blood Sugar in People With Type 2 Diabetes (NCT06542874) | Novo Nordisk A/S | 2024-08-07 |
| A Study to Evaluate the Efficacy and Safety of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DME (NCT06571045) | EyeBiotech Ltd. | 2024-08-07 |
| A Trial to Learn if Linvoseltamab is Safe and Works in Adults With Relapsed or Refractory Systemic Light Chain Amyloidosis (AL Amyloidosis) (NCT06292780) | Regeneron Pharmaceuticals | 2024-08-07 |
| Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06) (NCT06445972) | Merck Sharp & Dohme LLC | 2024-08-07 |
| Comparing 18F-FAPI PET-Guided Abdominal Radiotherapy Combined With Second-Line Standard Therapy and Cadonilimab Versus Second-Line Standard Therapy in Colorectal Cancer With Peritoneal Metastasis (NCT07079462) | Fudan University | 2024-08-07 |
| Vebreltinib Plus PLB1004 as the First-line Therapy for Patients With EGFRm+/MET+ Locally Advanced or Metastatic NSCLC. (NCT06574347) | Avistone Biotechnology Co., Ltd. | 2024-08-07 |
| Phase 1b/2 Platform Study of Select Immunotherapy Combinations in Participants With Advanced Non-small Cell Lung Cancer (NSCLC) (NCT06162572) | Servier Bio-Innovation LLC | 2024-08-07 |
| N-803 and PD-L1 t-haNK Combined With Bevacizumab for Recurrent or Progressive Glioblastoma (NCT06061809) | ImmunityBio, Inc. | 2024-08-07 |
| Targeting ODC as an Immunotherapeutic Target in STK11 (LKB1) Pathway-Deficient NSCLC (DFMO) (NCT06219174) | H. Lee Moffitt Cancer Center and Research Institute | 2024-08-07 |
| Gemcitabine, Cisplatin and Nab-Paclitaxel as Neoadjuvant Treatment for Patients With Resectable or Borderline Resectable Pancreatic Cancer (NCT06423326) | Emory University | 2024-08-06 |
| A Single-arm, Phase II Exploratory Study of Sintilimab in Combination With Chemoradiotherapy in Elderly Patients With Locally Advanced Gastric Cancer (NCT06555471) | The First Affiliated Hospital with Nanjing Medical University | 2024-08-06 |
| An Investigational Scan (89Zr-DFO-GmAb PET/CT) Compared to Contrast-Enhanced CT for the Detection of Recurrent Clear Cell Renal Cell Cancer After Surgery Comparing Carbonic Anhydrase IX (CAIX) PET CT to Conventional PET CT for Post-Op Staging in Kidney Cancer (NCT06447103) | Jonsson Comprehensive Cancer Center | 2024-08-06 |
| ADC-induced Neurotoxicity Treated With Duloxetine (NCT06551051) | Fudan University | 2024-08-06 |
| Fluorescence Imaging of IBD and RA Using Adalimumab-800CW (NCT03938701) | University Medical Center Groningen | 2024-08-06 |