| A Pharmacokinetic Study of Simufilam in Subjects With Impaired Hepatic Function (NCT06390410) | Cassava Sciences, Inc. | 2024-06-26 |
| Evaluate LAE102 in Healthy and Overweight/Obese Subjects (NCT06493084) | Laekna Limited | 2024-06-25 |
| Bioequivalence Study of Iron Sucrose Injection in Healthy Subjects (NCT06622148) | Sichuan Huiyu Pharmaceutical Co., Ltd | 2024-06-25 |
| pCCLCHIM-p47 (Lentiviral Vector Transduced CD34 Plus Cells) in Patients With p47 Autosomal Recessive Chronic Granulomatous Disease (AR-CGD) (NCT06253507) | National Institute of Allergy and Infectious Diseases (NIAID) | 2024-06-25 |
| Safety, Pharmacokinetics, and Preliminary Efficacy of BYON4413 in Acute Myeloid Leukemia and Myelodysplastic Neoplasms. (NCT06359002) | Byondis B.V. | 2024-06-25 |
| Phase I Study of HSK42360 in Solid Tumors With BRAF V600 Mutation (NCT06536400) | Haisco Pharmaceutical Group Co., Ltd. | 2024-06-25 |
| Evaluation of the High Intensity Focused Ultrasound (HIFU) Technique for Patients With Unresectable Pancreatic Tumor Treatment (PULS) (NCT06211933) | Centre Leon Berard | 2024-06-25 |
| A Study Comparing the Safety, Tolerability, and Pharmacokinetics of Sabirnetug IV and Sabirnetug + rHuPH20 SC in Healthy Participants (NCT06511570) | Acumen Pharmaceuticals | 2024-06-25 |
| IVW-1001 Phase 1/2 in Subjects With Dry Eye Disease (NCT06400459) | IVIEW Therapeutics Inc. | 2024-06-25 |
| A Study of E2086 in Healthy Adult Participants (NCT06481488) | Eisai Inc. | 2024-06-25 |
| To Evaluate Safety and Efficacy of FB-1603 in Hepatocellular Carcinoma Patient Receiving Transarterial Chemoembolization (NCT06478719) | Febico Biomedical Corp. | 2024-06-24 |
| Research on PSMA-Targeted Intraoperative Fluorescent Imaging Agents (NCT07101354) | Haitao Niu, MD | 2024-06-24 |
| Study of the BIOPIN 6 Naltrexone Implant in Healthy Adults (NCT06216132) | Akyso Therapeutics, LLC | 2024-06-24 |
| A Study of BW-20507 in Chinese Healthy Subjects and Subjects With Chronic Hepatitis B (NCT07595159) | Shanghai Argo Biopharmaceutical Co., Ltd. | 2024-06-24 |
| A Study to Test the Benefit of Vitamin B5 in Patients With Melanoma (NCT06377111) | University Health Network, Toronto | 2024-06-24 |
| A Study of TAK-279 in Healthy Chinese Adults (NCT06111547) | Takeda | 2024-06-24 |
| Personalized Antisense Oligonucleotide for a Single Participant With CHCHD10 ALS (NCT06977451) | n-Lorem Foundation | 2024-06-24 |
| A Bioequivalence Study of Citrate Free Mirikizumab (LY3074828) in Healthy Participants (NCT06475729) | Eli Lilly and Company | 2024-06-24 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AJ302-IM in Healthy Volunteers (NCT06625541) | AnnJi Pharmaceutical Co., Ltd. | 2024-06-24 |
| Effect of Latanoprost on Optic Nerve Perfusion (NCT06629129) | Zagazig University | 2024-06-24 |
| HP Pyruvate MRI in Cancers (NCT05697406) | University of Maryland, Baltimore | 2024-06-24 |
| Dose-finding for Dobutamine During Transitional Circulation in Very Preterm Infants (NCT06878742) | Instituto de Investigación Hospital Universitario La Paz | 2024-06-24 |
| A Study in Healthy Adult Participants to Assess the Pharmacokinetics, Immunogenicity, Safety, and Tolerability of a Ravagalimab Subcutaneous Formulation in a Pre-Filled Syringe (NCT06402513) | AbbVie | 2024-06-24 |
| A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors (NCT06307795) | Avistone Biotechnology Co., Ltd. | 2024-06-24 |
| Comparative Pharmacokinetic Study of Ramelteon Modified-Release Tablets and Ramelteon Tablets in Healthy Subjects (NCT06890715) | Overseas Pharmaceuticals, Ltd. | 2024-06-24 |
| A Study To Evaluate The Safety Of CMTX-101 In People With Cystic Fibrosis (NCT06159725) | Clarametyx Biosciences, Inc. | 2024-06-24 |
| A Bioequivalence Study of Two Different Dosage Form of Genakumab (NCT06451848) | Changchun GeneScience Pharmaceutical Co., Ltd. | 2024-06-24 |
| A Study to Compare Tablets and Capsules of Orforglipron (LY3502970) in Healthy Participants Who Are Obese or Overweight (NCT06440980) | Eli Lilly and Company | 2024-06-24 |
| A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AZD5148 in Healthy Adults (NCT06469151) | AstraZeneca | 2024-06-24 |
| An Exploratory Study of MT-2990 in Patients With AAV (NCT06196905) | Tanabe Pharma Corporation | 2024-06-24 |
| A Study to Assess the Safety, Pharmacokinetics, and Antitumor Activity of BC3195 in Patients With Advanced or Metastatic Cancer (NCT06548672) | Biocity Biopharmaceutics Co., Ltd. | 2024-06-24 |
| Trimetazidine Efficacy in Attenuating Paclitaxel-Induced Peripheral Neuropathy (NCT06459193) | Minia University | 2024-06-23 |
| Liposomal Irinotecan + Oxaliplatin + Bevacizumab Versus Liposomal Irinotecan + 5-FU/LV (NCT06782685) | Dai, Guanghai | 2024-06-23 |
| Effect of Dexmedetomidine on Hemodynamic Response to Endotracheal Intubation in Hypertensive Patients (NCT06712186) | Liaquat National Hospital & Medical College | 2024-06-22 |
| A Phase I/II Clinical Trial With SENS-501 in Children Suffering From Severe to Profound Hearing Loss Due to Otoferlin (OTOF) Mutations (NCT06370351) | Sensorion | 2024-06-21 |
| Bioequivalence Study Between YHP2205 and YHR2401 in Healthy Volunteers (NCT06359626) | Yuhan Corporation | 2024-06-21 |
| An Bioequivalence Study to Compare 10mg & 20mg of Senaparib Capsules in Healthy Chinese Subjects Under Fasting Condition (NCT07019194) | Impact Therapeutics, Inc. | 2024-06-21 |
| A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias (NCT07491172) | CRISPR Therapeutics AG | 2024-06-21 |
| Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1) (NCT06193174) | University of Alabama at Birmingham | 2024-06-21 |
| Clinical Trial of PCV24 in Adults (NCT06474377) | Sinovac Life Sciences Co., Ltd. | 2024-06-21 |
| A Study of APL-1501 Extended Release Capsules Compared to APL-1202 Immediate Release Tablets in Healthy Volunteers (NCT06435039) | Syneos Health | 2024-06-21 |
| An Investigational Study to Evaluate the Cardiac Safety Assessment (TQTc Study) of ESK-001 (NCT07378579) | Alumis Inc | 2024-06-21 |
| Enzalutamide Implants (Enolen) in Patients With Prostate Cancer (NCT06257693) | Alessa Therapeutics Inc. | 2024-06-21 |
| A Clinical Study to Evaluate CUD005 Injection in Patients with Liver Cirrhosis (NCT06671275) | Anhui Provincial Hospital | 2024-06-21 |
| A Study to Compare the Pharmacokinetics and Safety of QL1101 and EU-Avastin® in Healthy Volunteers (NCT06232902) | Qilu Pharmaceutical Co., Ltd. | 2024-06-20 |
| A Study to Evaluate the Efficacy, Safety, and Tolerability of E2086 Compared to Placebo and Active Comparator in Adult Participants With Narcolepsy Type 1 (NCT06462404) | Eisai Inc. | 2024-06-20 |
| Phase Ib Clinical Study of HDM1005 Injection (NCT06637020) | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | 2024-06-20 |
| Accuracy of Intraoral Photogrammetry Scanner in Complete Arch Digital Implant Impression (NCT06599294) | Ain Shams University | 2024-06-20 |
| A Study Comparing Trifarotene Cream 0.005% to AKLIEF® CREAM (US REFERENCE LISTED DRUG), AKLIEF™ CREAM (CANADIAN REFERENCE PRODUCT) in the Treatment of Acne Vulgaris (NCT06733402) | Sun Pharmaceutical Industries, Inc. | 2024-06-20 |
| Sequential Treatment of CD19 CARNK and 7x19 CAR-T in R/R B Cell Lymphoma (NCT06464861) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2024-06-20 |
| A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A) (NCT06428409) | Merck Sharp & Dohme LLC | 2024-06-20 |
| A Study of KYV-101, a CD19 CAR T Cell Therapy, in Participants With Treatment Refractory Progressive Multiple Sclerosis (NCT06451159) | Bruce Cree | 2024-06-20 |
| Multiple Ascending Dose Noribogaine PK/PD in Healthy Volunteers (NCT06480981) | DemeRx NB | 2024-06-20 |
| Ebastine in Combination With Docetaxel as a Treatment for Castration-resistant Metastatic Prostate Cancer (NCT06480110) | Rigshospitalet, Denmark | 2024-06-20 |
| A Study of MK-8527 in Participants With Moderate and Severe Renal Impairment (MK-8527-008) (NCT06295796) | Merck Sharp & Dohme LLC | 2024-06-20 |
| A Phase 1b Study of Menin Inhibitor SNDX- 5613 in Combination With Daunorubicin and Cytarabine in Newly Diagnosed Patients With Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged or NUP98 Alterations Disease (NCT05886049) | National Cancer Institute (NCI) | 2024-06-20 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single- and Multiple-Ascending Doses and Food Effect of BGB-45035 in Healthy Participants and in Adults With Autoimmune Dermatological Diseases (NCT06342713) | BeiGene | 2024-06-20 |
| A Trial of SHR-A2102 With Adebrelimab With or Without Other Antitumor Therapy in Advanced or Metastatic Esophageal Cancer (NCT06474468) | Shanghai Hengrui Pharmaceutical Co., Ltd. | 2024-06-20 |
| A Safety and Pharmacokinetics Study of Complarate (Tocilizumab Biosimilar Solution) and Actemra® in Healthy Volunteers (NCT06488521) | AO GENERIUM | 2024-06-20 |
| To Evaluate the Safety and Pharmacokinetic Interaction Between HODO-22251 and HODO-22252 in Healthy Adults (NCT06578676) | Hyundai Pharm | 2024-06-20 |
| CBM588 Capsules in Combination With Nivolumab and Ipilimumab for the Treatment of Advanced Stage Kidney Cancer (NCT06399419) | Osel, Inc. | 2024-06-19 |
| Study of SRP-1001 in Adult and Adolescent Participants With Facioscapulohumeral Muscular Dystrophy Type 1 (NCT06131983) | Sarepta Therapeutics, Inc. | 2024-06-19 |
| A Clinical Study of CD19 CAR-T in Active Systemic Lupus Erythematosus (NCT06106906) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2024-06-19 |
| A Clinical Study of TQH2929 Injection in Treatment With Generalized Pustular Psoriasis (GPP) (NCT06433531) | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | 2024-06-19 |
| A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome (NCT06501196) | BlossomHill Therapeutics | 2024-06-19 |
| RC48 Combined with Toripalimab As Neoadjuvant Therapy for Cisplatin Ineligible MIBC Patients (NCT06341400) | Zhujiang Hospital | 2024-06-19 |
| Avidination for RadionuclideTHerapy in Nonpalpable Breast Cancer (NCT06390241) | Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS | 2024-06-19 |
| A Randomized, Double-blind, Placebo-controlled Phase I Clinical Trial to Evaluate the Safety and Pharmacokinetic Profile of Single and Multiple Dose Escalation Topical Dermal Administration of SHR0302 Alkali Gel in Healthy Subjects (NCT07098117) | Jiangsu HengRui Medicine Co., Ltd. | 2024-06-19 |
| A Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics and the Effect of Probenecid on Povorcitinib Pharmacokinetics When Administered Orally to Healthy Adult Participants (NCT06416800) | Incyte Corporation | 2024-06-19 |
| Descartes-15 for Patients With Relapsed/Refractory Multiple Myeloma (NCT06304636) | Cartesian Therapeutics | 2024-06-19 |
| T Cell Receptor Gene-Engineered T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor (NCT06484556) | Tao Zhang | 2024-06-19 |
| A Study to Evaluate the Safety and Efficacy of BEAM-302 in Adult Patients With Alpha-1 Antitrypsin Deficiency (AATD) (NCT06389877) | Beam Therapeutics Inc. | 2024-06-19 |
| A Study to Evaluate LB1410 in Combination With LB4330 in Patients With Advanced or Metastatic Solid Tumors (NCT06468358) | L & L Bio Co., Ltd., Ningbo, China | 2024-06-19 |
| A Study of Recombinant Oncolytic Virus M1(VRT106) in Patients With Solid Tumors (NCT06368921) | Guangzhou Virotech Pharmaceutical Co., Ltd. | 2024-06-19 |
| Ticagrelor Tablets 90 mg Relative to Originator Ticagrelor Tablets 90 mg (NCT06233266) | Bio-innova Co., Ltd | 2024-06-18 |
| A Phase 1 Study of TE-8214 Solution in Healthy Volunteers (NCT06372652) | Immunwork, Inc. | 2024-06-18 |
| LB-100 (PP2A Inhibitor) and Atezolizumab (PD-L1 Inhibitor) in Metastatic Colorectal Cancer Patients (NCT06012734) | The Netherlands Cancer Institute | 2024-06-18 |
| PhI/II Study of Amivantamab and Tepotinib Combo in MET-altered Non-small Cell Lung Cancer (NCT06083857) | M.D. Anderson Cancer Center | 2024-06-18 |
| CD5 Chimeric Antigen Receptor (CAR) T Cells in Subjects With Relapsed or Refractory T-cell Malignancies (NCT06316856) | Beijing GoBroad Hospital | 2024-06-18 |
| A Study of Avacopan in Participants With Normal Renal Function and Participants With End-Stage Renal Disease (ESRD) (NCT06468826) | Amgen | 2024-06-18 |
| Phase I, Open-labeled, Dose-escalation, Dose-expansion Study Evaluating the Safety, Tolerance, Pharmacokinetics, and Activity of IUAb190708 in Patients With Advanced or Recurrent Solid Tumors (NCT07584954) | Jun Zhou | 2024-06-18 |
| Peptide-coupled Red Blood Cells for the Treatment of Multiple Sclerosis (NCT06430671) | Cellerys AG | 2024-06-18 |
| Study of SGR-3515 In Participants With Advanced Solid Tumors. (NCT06463340) | Schrödinger, Inc. | 2024-06-18 |
| A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors (NCT06399757) | Apollo Therapeutics Ltd | 2024-06-18 |
| A Study to Evaluate the Effect of Injection Site on PK of Astegolimab in Healthy Subjects (NCT06462118) | Genentech, Inc. | 2024-06-17 |
| A First-in-Human Phase I Trial With Antibody Drug Conjugate ADCT-701 in Neuroendocrine Tumors, Carcinomas and Malignant Peripheral Nerve Sheath Tumors (NCT06041516) | National Cancer Institute (NCI) | 2024-06-17 |
| Implantation of Cartilage Mini-grafts Made From Donor Cells to Treat Chondral Lesions of the Knee (NCT06897111) | Vanarix SA | 2024-06-17 |
| Chronic Subdural Hematoma Treatment With Intra-Arterial Bevacizumab Injection (NCT06510582) | The Cooper Health System | 2024-06-17 |
| Exploratory Clinical Study of HRS-4642 Combined With Adebrelimab in the Treatment of Advanced Pancreatic Ductal Adenocarcinoma (NCT06427239) | Fudan University | 2024-06-17 |
| Study of ABBV-383 Assessing Adverse Events and Clinical Activity With Subcutaneous (SC) Injection in Adult Participants With Relapsed or Refractory Multiple Myeloma (NCT06223516) | AbbVie | 2024-06-17 |
| Pharmacokinetics, Biodistribution, Radiation Dose and Safety Study of 68Ga-NYM005 in Patients (NCT06389682) | Norroy Bioscience Co., LTD | 2024-06-17 |
| Safety and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Healthy Adults 50 Years of Age and Over (NCT06569823) | Dynavax Technologies Corporation | 2024-06-17 |
| A Study of 3HP-2827 in Treatment of Unresectable or Metastatic Solid Tumors With FGFR2 Alterations (NCT06378593) | 3H (Suzhou) Pharmaceuticals Co., Ltd. | 2024-06-17 |
| Evaluation of Topical ATR12-351 in Adults With Netherton Syndrome (NCT06137157) | Azitra Inc. | 2024-06-16 |
| A Trial to Evaluate the Safety and Immunogenicity of an Investigational Vaccine for the Prevention of Yellow Fever, and of an Investigational Vaccine for the Prevention of Rabies, in Healthy Adults (NCT06998004) | AstriVax Therapeutics | 2024-06-16 |
| GS-441524 for COVID-19 SAD, FE, and MAD Study in Healthy Subjects (NCT06274853) | National Center for Advancing Translational Sciences (NCATS) | 2024-06-15 |
| A Comparative Study of the Pharmacokinetic Profiles of Timolol Maleate Ophthalmic Gel With Timolol Maleate Gel (NCT06813807) | Auson Pharmaceuticals Inc. | 2024-06-15 |
| Phase Ib/II Clinical Study of Adebrelimab in Combination With Decitabine, Albumin-bound Paclitaxel, and Gemcitabine for the First-line Treatment of Metastatic Pancreatic Cancer (NCT06454448) | Tianjin Medical University Cancer Institute and Hospital | 2024-06-15 |
| IM83 Clinical Study of CAR-T Cell Therapy in Patients With Relapsed or Refractory Osteosarcoma (NCT06412458) | Beijing Immunochina Medical Science & Technology Co., Ltd. | 2024-06-15 |
| Effects of Platelet-Rich Fibrin on Postoperative Outcomes Following Nasosinusal Surgery (NCT07645053) | Hospital Edmundo Vasconcelos | 2024-06-15 |