| A Trial of SHR-A2102 With Adebrelimab With or Without Other Antitumor Therapy in Advanced or Metastatic Non-small Cell Lung Cancer (NCT06512051) | Shanghai Hengrui Pharmaceutical Co., Ltd. | 2024-07-30 |
| Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer (NCT06307548) | Roswell Park Cancer Institute | 2024-07-30 |
| Bioequivalence Study of Diacerein 50 mg Capsule in Healthy Thai Volunteers (NCT06308068) | International Bio service | 2024-07-30 |
| A Study in Healthy Men to Test Whether Zongertinib Affects How 3 Other Medicines (Midazolam, Omeprazole, and Repaglinide) Are Taken up and Processed by the Body (NCT06494761) | Boehringer Ingelheim | 2024-07-30 |
| A Study of RAY1225 at Different Injection Sites in Participants With Different Body Sizes (NCT06577428) | Guangdong Raynovent Biotech Co., Ltd | 2024-07-30 |
| Study on Sapropterin Dihydrochloride Oral Suspension in Healthy Subjects (NCT06481709) | APR Applied Pharma Research s.a. | 2024-07-30 |
| Study to Demonstrate Pharmacokinetic and Pharmacodynamic Similarity Between NKF-INS(A), US-NovoLog®, and EU-NovoRapid® (NCT06492226) | Xentria, Inc. | 2024-07-30 |
| Nab-Paclitaxel/STI-3031 Complex (AP160-Complex) for the Treatment of Advanced or Metastatic Solid Tumors (NCT05653661) | Mayo Clinic | 2024-07-30 |
| PA-001 Ph.1 Study in Healthy and Elderly Subjects (NCT07518771) | PeptiDream Inc. | 2024-07-30 |
| Combination of Equisetum Arvense and Palmitoylethanolamide (PEA) for the Management of Patients With Chronic Pain in a Before-after Study (NCT07110480) | noiVita Srls | 2024-07-29 |
| A Study of XS-02 Capsules in Patients With Advanced Solid Tumors (NCT06531486) | NovaOnco Therapeutics Co., Ltd. | 2024-07-29 |
| NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer. (NCT06379217) | Novartis Pharmaceuticals | 2024-07-29 |
| Clinical Study of 18F-LNC1007 Injection PET/CT (NCT06471712) | Yantai LNC Biotechnology Singapore PTE. LTD. | 2024-07-29 |
| ATRA and Carfilzomib in Plasma Cell Myeloma Patients (NCT06536413) | The Methodist Hospital Research Institute | 2024-07-29 |
| A First-in-Human, Single- and Multiple-Ascending Dose Study of YH35995 in Healthy Adult Male Participants (NCT06517914) | Yuhan Corporation | 2024-07-29 |
| Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells (NCT06305299) | UNC Lineberger Comprehensive Cancer Center | 2024-07-29 |
| To Learn How Different Forms of Study Medicine Are Taken up Into the Blood and the Effect of Food on Study Medicine in Healthy Adults (NCT06593054) | Pfizer | 2024-07-29 |
| A Study of IBI3003 in Subjects With Relapsed or Refractory Multiple Myeloma (NCT06083207) | Innovent Biologics (Suzhou) Co. Ltd. | 2024-07-29 |
| SRG-514 Administered Intraoperatively to Patients Undergoing Breast-conserving Cancer Surgery (NCT06300411) | SURGE Therapeutics | 2024-07-29 |
| Study of the Effect of HFA-152a and HFA-134a Propellants on Mucociliary Clearance in Healthy Participants (NCT06506266) | GlaxoSmithKline | 2024-07-29 |
| HDM1002 Tablets in Chinese Overweight and Obese Adult Subjects (NCT06520540) | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | 2024-07-28 |
| A Study to Evaluate the Relative Bioavailability and Food Effect of a New Tablet Formulation of VX-993 (NCT06508762) | Vertex Pharmaceuticals Incorporated | 2024-07-26 |
| Dose Optimization of Caffeine for HIE (NCT06448780) | University of North Carolina, Chapel Hill | 2024-07-26 |
| Study of GS-2121 Given Alone or in Combination in Adults With Advanced Solid Tumors (NCT06532565) | Gilead Sciences | 2024-07-26 |
| Treatment of Cancer With Immune Checkpoint Inhibition Therapy Boosted by High Intensity Focused Ultrasound Histotripsy (NCT06524570) | UMC Utrecht | 2024-07-26 |
| Biology-Guided Radiation Therapy for the Treatment of Patients With Bone Metastases (NCT06549478) | City of Hope Medical Center | 2024-07-26 |
| CiNPWT Lower Extremity Amputations (Closed Incision Neagtive Pressure Wound Therapy) (NCT06493539) | University of Southern California | 2024-07-25 |
| A Phase Ib Clinical Study of AC-003 Capsules in Subjects With aGVHD. (NCT07070674) | Accro Bioscience (Suzhou) Limited | 2024-07-25 |
| Evaluation of a Targeted Magnetic Resonance Imaging Contrast Agent in Prostate Cancer Patients (NCT06262139) | Songqi Gao | 2024-07-25 |
| Gilteritinib for the Treatment of ALK NSCLC (NCT06225427) | University of Michigan Rogel Cancer Center | 2024-07-25 |
| A Study of Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015) (NCT06442436) | Merck Sharp & Dohme LLC | 2024-07-24 |
| Relative Bioavailability Study of HU6 (NCT06486558) | Rivus Pharmaceuticals, Inc. | 2024-07-24 |
| A Study of MRG006A in the Treatment of Patients With Advanced Solid Tumors (NCT07093970) | Lepu Biopharma Co., Ltd. | 2024-07-24 |
| A Study to Evaluate the Safety and Efficacy of ATHENA CAR-T in Subjects With Systemic Lupus Erythematosus (NCT06373991) | EdiGene Inc. | 2024-07-24 |
| A Study of BL-M17D1 in Patients With Locally Advanced or Metastatic HER2 Positive/Lower Expression Gastrointestinal Cancer and Other Solid Tumors (NCT06500052) | Sichuan Baili Pharmaceutical Co., Ltd. | 2024-07-24 |
| To Evaluate the Pharmacokinetics and Safety of TQD3524 for Injection in Renal Impairment Subjects (NCT06522945) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2024-07-24 |
| Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer (NCT05896839) | National Cancer Institute (NCI) | 2024-07-24 |
| Mechanisms of Diuretic Resistance in Heart Failure, Aim 3 (NCT06209359) | Yale University | 2024-07-24 |
| A Trial of HRS-9813 in Healthy Volunteers (NCT06514963) | Guangdong Hengrui Pharmaceutical Co., Ltd | 2024-07-24 |
| The Effect of Novel D3 Use as a Mouthwash in COVID-19 Patients (NCT07068282) | King Faisal Specialist Hospital & Research Center | 2024-07-24 |
| Study of CEA Targeting CAR-T (PTC13) in the Treatment of CEA-Positive Advanced Malignant Solid Tumors (NCT06821048) | Weijia Fang, MD | 2024-07-24 |
| JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation (NCT06386146) | Jacobio Pharmaceuticals Co., Ltd. | 2024-07-24 |
| A Study to Assess the Pharmacokinetics of AZD6793 When Administered Alone and in Combination With Itraconazole in Healthy Participants. (NCT06494644) | AstraZeneca | 2024-07-23 |
| Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma (NCT06410248) | Northwestern University | 2024-07-23 |
| A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors (NCT06427941) | BeOne Medicines | 2024-07-23 |
| A Study of Combination Therapy With Amivantamab and Docetaxel in Participants With Metastatic Non-small Cell Lung Cancer (NCT06532032) | Janssen Research & Development, LLC | 2024-07-23 |
| A Clinical Trial of SIBP-A17 Injection in the Treatment of Advanced Solid Tumor Patients. (NCT06512116) | Shanghai Institute Of Biological Products | 2024-07-23 |
| A Study to Assess Pharmacokinetic Exposures Following Intravenous and Subcutaneous Administration of Risankizumab in Healthy Participants (NCT06487572) | AbbVie | 2024-07-23 |
| A Study to Learn About Whether BAYH006689 Causes Skin Irritation When Applied as a Topical Gel in Healthy Participants (NCT06511973) | Bayer | 2024-07-23 |
| Phase I Study of ICP-332 in Healthy Subjects (NCT06530966) | InnoCare Pharma Inc. | 2024-07-23 |
| A Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JMT202 (NCT06564467) | Shanghai JMT-Bio Inc. | 2024-07-23 |
| Evaluate the Effects of Food on the Pharmacokinetics of SIM0270 (NCT06536036) | Jiangsu Simcere Pharmaceutical Co., Ltd. | 2024-07-23 |
| Dapagliflozin Tablet 10 mg Relative to Forxiga® Tablets 10 mg (NCT06233045) | Bio-innova Co., Ltd | 2024-07-23 |
| Oncolytic Adenovirus TILT-123 With Pembrolizumab as Treatment for Refractory Non-Small Cell Lung Cancer (NCT06125197) | TILT Biotherapeutics Ltd. | 2024-07-23 |
| A Study of IMM2510 + IMM27M Combination Therapy in Patients With Advanced Solid Tumors (NCT06764836) | ImmuneOnco Biopharmaceuticals (Shanghai) Inc. | 2024-07-23 |
| Safety and Efficacy Study of Collagenase CNT201 Injection for Treatment of Dupuytren's Contracture (NCT07640425) | CONNEXT | 2024-07-23 |
| A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03) (NCT06362252) | Daiichi Sankyo | 2024-07-22 |
| A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors (NCT06440005) | Angiex, Inc. | 2024-07-22 |
| Comparative Evaluation of Sustained Acoustic Medicine Device on Circulation (NCT06510062) | ZetrOZ, Inc. | 2024-07-22 |
| The Effectiveness of Astaxanthin Supplementation on the Clinical Symptoms and Cardio-metabolic Profile in Women with Polycystic Ovary Syndrome (NCT06642363) | Isfahan University of Medical Sciences | 2024-07-22 |
| Food Effect and Relative Bioavailability Study of VC004 Capsules in Healthy Adult Subjects (NCT06529445) | Jiangsu vcare pharmaceutical technology co., LTD | 2024-07-22 |
| Clascoterone for Steroid-related Acne Vulgaris in Transgender Male Patients Receiving Masculinizing Hormone Therapy (NCT05891795) | Stanford University | 2024-07-22 |
| Study to Assess Xevinapant in Preoperative Subjects With Recurrent High-Grade Glioma (rHGG) (NCT06463184) | H. Lee Moffitt Cancer Center and Research Institute | 2024-07-22 |
| Safety, Tolerability, and Pharmacokinetics of PA9159 Inhalation Aerosol in Healthy Adult Subjects (NCT06916273) | Anhui Palo Alto Pharmaceuticals, Inc. | 2024-07-22 |
| A Clinical Study Evaluating the Safety, Tolerability, and Initial Efficacy of JWK008 in Patients With Mucopolysaccharidosis Type I (NCT06519552) | West China Hospital | 2024-07-22 |
| [14C] Mass Balance Clinical Trial of Azvudine in Healthy Male Subjects (NCT07002281) | Henan Genuine Biotech Co., Ltd. | 2024-07-22 |
| Clinical Trial to Investigate the Effects of Food on the Pharmacokinetics and Safety of Orally Administered Radotinib (NCT06461078) | Il-Yang Pharm. Co., Ltd. | 2024-07-22 |
| A Study of TQB2102 for Injection in the Treatment of HER2-positive Biliary Tract Cancer (NCT06431490) | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | 2024-07-22 |
| An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors (NCT06480552) | Teva Branded Pharmaceutical Products R&D LLC | 2024-07-22 |
| To Evaluate Safety and Immunogenicity of a Prophylactic Plasmid DNA (NCT06436911) | Entos Pharmaceuticals Inc. | 2024-07-22 |
| Mitoxantrone for Venetoclax Resistant Acute Myeloid Leukemia (NCT06429449) | University of Colorado, Denver | 2024-07-21 |
| A Study of AK112 Monotherapy in Advanced/Metastatic Renal Cell Carcinoma (NCT06472895) | Peking University Cancer Hospital & Institute | 2024-07-20 |
| Clinical Study on the Safety and Preliminary Efficacy of hUC-MSCs Intravenous Infusion Therapy for ARDS (NCT06505941) | Southeast University, China | 2024-07-20 |
| Clinical Study of A-319 in the Treatment of Active/Refractory Systemic Lupus Erythematosus (NCT06400537) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2024-07-20 |
| High Dose Ascorbic Acid (HDAA) in Patients With Plasma Cell Disorders (NCT06313502) | University of Arkansas | 2024-07-19 |
| A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacokinetic of TQB3702 Tablets in Healthy Adult Subjects (NCT06448273) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2024-07-19 |
| Assessment of the Pharmacokinetics and Safety of ANT3310 Combined With Meropenem in Renally Impaired Subjects (NCT06527677) | Antabio | 2024-07-19 |
| A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD (NCT06405633) | Wave Life Sciences USA, Inc. | 2024-07-19 |
| A Study of HS-10516 in Patients With VHL Syndrome Associated Tumors (NCT06553339) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2024-07-19 |
| IB/IIa Study of MG-K10 in Adolescent Moderately Severe Patients (NCT06765005) | Shanghai Mabgeek Biotech.Co.Ltd | 2024-07-19 |
| Trial of 225Ac-DOTATATE (RYZ101) in Subjects With ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs. (NCT06590857) | RayzeBio, Inc. | 2024-07-19 |
| An Open-label, Single-arm Study of JWCAR201 in the Treatment of Relapsed or Refractory Diffuse Large B-cell Lymphoma (NCT06517004) | Fudan University | 2024-07-18 |
| Autologous CAR-T Cells Targeting B7-H3 in PDAC (NCT06158139) | UNC Lineberger Comprehensive Cancer Center | 2024-07-18 |
| Study to Evaluate the Effect of Bepirovirsen on Cardiac Conduction as Assessed by 12-lead Electrocardiogram in Healthy Volunteers (NCT06422767) | GlaxoSmithKline | 2024-07-18 |
| Multiple Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of THDBH120 in Chinese Patients With Obesity (NCT06951945) | Tonghua Dongbao Pharmaceutical Co.,Ltd | 2024-07-18 |
| A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1) (NCT06521554) | Nuvalent Inc. | 2024-07-18 |
| A Research Study Looking Into the Effect of NNC0519-0130 on Blood Levels of a Birth Control Pill and Emptying of the Stomach in Women After Menopause (NCT06513104) | Novo Nordisk A/S | 2024-07-18 |
| A Study of BL-B16D1 in Patients With Locally Advanced or Metastatic Solid Tumors (NCT06475131) | Sichuan Baili Pharmaceutical Co., Ltd. | 2024-07-18 |
| Autologous Tumor-Infiltrating Lymphocyte (GTE-001 Injection ) for Treatment of Patients With Advanced Lung Adenocarcinoma (NCT06491225) | Grit Biotechnology | 2024-07-18 |
| The Food Effect on Pharmacokinetics of DA-302168S (NCT06534346) | Chendu DIAO Pharmaceutical Group CO., LTD. | 2024-07-18 |
| Comparison of HRS-5965 Capsules and Tablets in Healthy Subjects (NCT06490991) | Chengdu Suncadia Medicine Co., Ltd. | 2024-07-17 |
| A Study of Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Plus Enfortumab Vedotin (EV) With and Without Pembrolizumab in Advanced Urothelial Carcinoma (MK-3475-04C/KEYMAKER-U04) (NCT06483334) | Merck Sharp & Dohme LLC | 2024-07-17 |
| Open, Randomized Crossover Study on PK, PD, Biopotency, and Bioavailability of Insulin Capsules in Healthy Chinese Males (NCT06519604) | Shanghai Jiao Tong University School of Medicine | 2024-07-17 |
| Intra-tumoral Mitazalimab (CD40 Antibody) With Irreversible Electroporation (IRE) in Locally Advanced Pancreas Cancer (NCT06205849) | University of California, San Diego | 2024-07-17 |
| A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease (NCT06481306) | Bristol-Myers Squibb | 2024-07-17 |
| A First-in-human Study of the Safety of an Immunosuppressive Antibody (IMP761) in Healthy Volunteers (NCT06637865) | Immutep S.A.S. | 2024-07-17 |
| FAPI-74 PET/CT in Adults With Fibrosis (NCT06413355) | Abramson Cancer Center at Penn Medicine | 2024-07-16 |
| A Drug-Drug Interaction (DDI) Study of ADC189 With Itraconazole in Healthy, Adult Subjects (NCT06589635) | Jiaxing AnDiCon Biotech Co.,Ltd | 2024-07-16 |
| Study of Injectable Naltrexone and Oral Bupropion Among Cigarette Smokers With Schizophrenia (NCT06374290) | The University of Texas Health Science Center, Houston | 2024-07-16 |
| EXL01 in Combination With Nivolumab for Advanced NSCLC Refractory to Immunotherapy. (NCT06448572) | University Hospital, Lille | 2024-07-16 |