| Bioequivalence Study of Vortioxetine in 20 mg Coated Tablets in Healthy Subjects Under Fasting Conditions (NCT07624357) | ADIUM | 2025-03-18 |
| Safety of Anal Curcumin (NCT06626230) | Lisa Flowers | 2025-03-17 |
| Personalized Antisense Oligonucleotide Therapy for A Single Participant With LMNB1 Mutation Associated Autosomal Dominant Leukodystrophy (ADLD) (NCT06816498) | n-Lorem Foundation | 2025-03-17 |
| A Phase 1 Trial to Evaluate the Safety, Tolerability, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of VIS171 in Participants With Autoimmune Disease(s) (NCT06799520) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2025-03-17 |
| A Study to Evaluate MWN109 Injection in Healthy Subjects (NCT06859853) | Shanghai Minwei Biotechnology Co., Ltd | 2025-03-17 |
| Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good Health (NCT06796686) | National Institute of Allergy and Infectious Diseases (NIAID) | 2025-03-17 |
| A Study to Evaluate ART101 in Adult Participants With Hypertension (NCT06780033) | Arnatar Therapeutics, Inc. | 2025-03-17 |
| A Single-arm, Open-label Clinical Study to Evaluate the Efficacy and Safety of VRT106 in Combination With Chemotherapy for Resectable Pancreatic Cancer (NCT06758544) | Guangdong Provincial People's Hospital | 2025-03-17 |
| D2C7-IT + 2141-V11 Combination Post-resection in rGBM (NCT06455605) | Darell Bigner | 2025-03-17 |
| Intrathecal Dual Checkpoint Inhibitor (PD-1 and CTLA-4) in Combination With Pemetrexed for Leptomeningeal Metastasis (NCT06809530) | Guangzhou Medical University | 2025-03-17 |
| A Study of GNC-038 Tetra-specific Antibody Injection in Patients With Rheumatoid Arthritis (NCT06857227) | Sichuan Baili Pharmaceutical Co., Ltd. | 2025-03-17 |
| Pharmacokinetics, Safety, and Lung Deposition of 99mTc-DTPA Delivered Via the EDDIS System in Healthy Volunteers (NCT07053696) | Andrey Petrov | 2025-03-17 |
| Trial to Evaluate the Safety & Tolerability of JBZ-001 in Pts With Advanced Solid and Hematological Malignancies (NCT06801002) | Jabez Bioscience, Inc | 2025-03-17 |
| Efficacy and Safety of HN2301 in Autoimmune Diseases（AIDs） (NCT06801119) | Shenzhen MagicRNA Biotechnology Co., Ltd | 2025-03-16 |
| A Study Evaluating the Food Effect on the Pharmacokinetics of SSS17 Capsules in Chinese Healthy Subjects (NCT07024888) | Shenyang Sunshine Pharmaceutical Co., LTD. | 2025-03-16 |
| Opioid-Free Anesthesia in Colorectal Surgery, 2025 (OFA-CRC-2025) (NCT07771049) | Hospital Universitario La Fe | 2025-03-15 |
| Chiglitazar Sodium Combined With Venetoclax and Azacitidine (CVA) for the Treatment of R/R AML (NCT06737523) | The First Affiliated Hospital of Xiamen University | 2025-03-15 |
| Randomized Controlled Trial of Berberine in Combination With Doxycycline in the Treatment of Chronic Endometritis (NCT07180563) | The Fourth Affiliated Hospital of Zhejiang University School of Medicine | 2025-03-15 |
| Intranasal Administration of Dodecyl Creatine Ester (CBT101) in Healthy Male Subjects (NCT07050316) | Ceres Brain Therapeutics | 2025-03-14 |
| A Study of the Blood Levels of Palovarotene in Participants With Abnormal Liver Function Compared to Healthy Adult Participants After Intake of a Single Dose (NCT06908954) | Ipsen | 2025-03-14 |
| A Study to Evaluate AMG 133 in Participants With Varying Degrees of Hepatic Impairment or Normal Hepatic Function (NCT07428525) | Amgen | 2025-03-14 |
| Study of the Safety, Tolerability, Electrophysiological Effects and Efficacy of DMT in Humans (NCT06671977) | Deepak C. D'Souza | 2025-03-14 |
| Study of SHR-1209 Administered by Single-site or Multiple-site Subcutaneous Injections in Healthy Volunteers (NCT06837077) | Jiangsu HengRui Medicine Co., Ltd. | 2025-03-14 |
| Study on the Safety, Tolerability, and Pharmacokinetics of PA9159 Nasal Spray in Healthy Adult Subjects (NCT07345442) | Anhui Palo Alto Pharmaceuticals, Inc. | 2025-03-14 |
| A Study to Investigate The Effect of Pimicotinib on The Pharmacokinetics of Metformin, Fexofenadine and Rosuvastatin In Healthy Subjects (NCT06779253) | Abbisko Therapeutics Co, Ltd | 2025-03-14 |
| A Study to Assess a New Medicine Called IPN01195 When Administered Alone in Adults With Advanced Solid Tumours (NCT06833008) | Ipsen | 2025-03-14 |
| A Study to Evaluate the Drug-Drug Interaction of EDP-323 With Midazolam, Caffeine, and Rosuvastatin in Healthy Participants (NCT06917508) | Enanta Pharmaceuticals, Inc | 2025-03-13 |
| A Study of the Pharmacokinetics and Safety of CS0159 in Subjects With Hepatic Injury (NCT06888115) | Cascade Pharmaceuticals, Inc | 2025-03-13 |
| A Dose Escalation Study of NanO2 in Patients With Mild Respiratory Distress (NCT06658535) | NuvOx LLC | 2025-03-13 |
| A Phase Ib Study of RC148 as Monotherapy or Combination for Locally Advanced or Metastatic NSCLC (NCT06883630) | RemeGen Co., Ltd. | 2025-03-13 |
| A Study to Evaluate Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Multiple Doses of VIS954 (NCT06937593) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2025-03-13 |
| Safety and Efficacy of HCB101 in Combination With Multiple Agents in Patients With Advanced Solid Tumors (NCT06771622) | FBD Biologics Limited | 2025-03-13 |
| METR-NK Cells in Combination With Anti-angiogenic Neoadjuvant Therapy for Advanced Epithelial Ovarian Cancer (NCT06884345) | Anhui Provincial Cancer Hospital | 2025-03-13 |
| Safety and Immunogenicity of the Recombinant Zoster Vaccine, LYB004 in Adults Aged 40 Years and Older (NCT06874842) | Guangzhou Patronus Biotech Co., Ltd. | 2025-03-13 |
| A Phase 1 Study of STX-0712 in Patients With Advanced Hematological Malignancies (CMML and AML) (NCT06950034) | Solu Therapeutics, Inc | 2025-03-13 |
| Study to Learn About How the Study Medicines Called PF-07976016 and PF-06882961 Are Taken Up by the Body, and if Either of Them Change How the Body Processes the Other Medicine in Otherwise Healthy Adults With Overweight or Obesity (NCT06910839) | Pfizer | 2025-03-13 |
| Study of a Tankyrase Inhibitor RK-582 for Patients With Unresectable Metastatic Colorectal Cancer (NCT06853496) | Eiji Shinozaki | 2025-03-13 |
| Resiniferatoxin for the Management of Refractory Morton s Neuroma Pain (NCT05695339) | National Institutes of Health Clinical Center (CC) | 2025-03-13 |
| Phase I PK and Safety Study of Ondansetron Inhalation Powder (NCT07498751) | Luxena Pharmaceuticals, Inc. | 2025-03-13 |
| Evaluation of K9 in Subjects With Diabetic Macular Edema (DME) (NCT06781255) | Michelle Abou-Jaoude | 2025-03-13 |
| RT-310 Safety and Feasibility BPH Study (NCT07264205) | Resurge Therapeutics Inc. | 2025-03-13 |
| A Single-arm, Open-label Clinical Study to Evaluate the Efficacy and Safety of VRT106 in Combination With Chemotherapy for Advanced Pancreatic Cancer (NCT06866977) | Xiangya Hospital of Central South University | 2025-03-12 |
| Multiple Dose Study for a New Medication to Potentially Treat Liver Diseases (NCT06891365) | Novo Nordisk A/S | 2025-03-12 |
| Safety and Efficacy of LOw DOse COlchicine in Patients With STatin INTolerance: the LODOCO STINT Pilot Study (NCT06874192) | Virginia Commonwealth University | 2025-03-12 |
| Laparoscopic-Assisted Transversus Abdominus Plane Block Versus Intraperitoneal Irrigation of Local Anesthetic for Patients Undergoing Laparoscopic Cholecystectomy (NCT06714279) | Royal College of Surgeons, Ireland | 2025-03-12 |
| RNA Lipid Particles Targeting Pediatric Recurrent Intracranial Malignancies and Other systEmic Solid Tumors (NCT05660408) | University of Florida | 2025-03-12 |
| Dose Escalation of Allogeneic Adipose Derived Stroma/Stem Cells for the Treatment of Crohn's Fistula (NCT06636032) | University Hospital, Toulouse | 2025-03-12 |
| A Study of Pharmacokinetics, Safety, and Immunogenicity of BCD-057 100 mg/mL, BCD-057 50 mg/mL, and Humira 100 mg/mL in Healthy Subjects (NCT07181694) | Biocad | 2025-03-12 |
| A Study to Learn About How Safe BAY 3389934 is, Its Suitable Dose, and How it Affects the Participants With Sepsis Induced Coagulopathy (NCT06854640) | Bayer | 2025-03-12 |
| Single-ascending Dose Study of Kylo-12 in Healthy Subjects (NCT06783881) | Kylonova (Xiamen) Biopharma co., LTD. | 2025-03-12 |
| A Study to Evaluate Metabolism, Excretion, and Mass Balance of [14C]Vapendavir (NCT06834295) | Altesa Biosciences, Inc. | 2025-03-12 |
| TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes With Increased Blasts (NCT03816319) | National Cancer Institute (NCI) | 2025-03-12 |
| A Study of NH280105 in Healthy Adult Participants (NCT06870058) | Jiangsu Nhwa Pharmaceutical Co., Ltd. | 2025-03-12 |
| To Observe Haemodynamic Parameters Including, Heart Rate, Blood Pressure, Respiratory Rate , and Oxygen Saturation, With or Without Giving Reversal Agent on Extubation, in Patients Receiving Single Shot of Atracurium , and to Observe Post Operative Residual Paralysis and Airway Reflexes in PACU. (NCT07097441) | Ziauddin University | 2025-03-12 |
| Pathways 2 Success (NCT06831123) | University of Minnesota | 2025-03-12 |
| Clinical Study of HRS-2129 for Postoperative Analgesia in Orthopaedics (NCT06780267) | Shandong Suncadia Medicine Co., Ltd. | 2025-03-11 |
| Evaluation of Cirrhotic Cardiomyopathy by Cardiac MRI in Patients Waiting for Liver Transplant. (NCT06327308) | Centre Hospitalier Universitaire de Besancon | 2025-03-11 |
| A Study to Evaluate the Tolerability, Safety, and PK of AST-201 in Patients With GPC3-positive Advanced Solid Tumors (NCT06687941) | Aptamer Sciences, Inc. | 2025-03-11 |
| NT-101 Topical Ophthalmic Solution in Patients With Wet AMD (NCT06704009) | NexThera Co., Ltd. | 2025-03-11 |
| A Study to Assess the Potential for Airway Sensitivity Reactions With Propellants HFA-152a (Test) and HFA-134a (Reference) Administered Via Pressurized Inhalers in Adults With Mild Asthma (NCT06702462) | GlaxoSmithKline | 2025-03-11 |
| A Drug-drug Interaction Study With TS-172 in Healthy Adult Male Subjects (NCT06837142) | Taisho Pharmaceutical Co., Ltd. | 2025-03-11 |
| Evaluate the Pharmacokinetics of Oral Arsenic Trioxide Solution Under Fasting and Fed Conditions, to Compare Intravenous Arsenic Trioxide, in Acute Promyelocytic Leukemia (NCT06882031) | SDK Therapeutics, Inc. | 2025-03-11 |
| Brodalumab in the Treatment of Immune-Related Adverse Events (NCT06673329) | Brian Henick, MD | 2025-03-11 |
| A Study to Investigate the Safety and Efficacy of IOV-3001 in Adults With Advanced Melanoma Who Will Receive Lifileucel (NCT06940739) | Iovance Biotherapeutics, Inc. | 2025-03-11 |
| A Trial to Assess the Effect of Kidney Impairment on How AMG 133 is Absorbed, Broken Down, and Eliminated by the Body (NCT07429045) | Amgen | 2025-03-11 |
| A Study of HS-10518 in Healthy Adult Premenopausal Females in China (NCT07264192) | West China Second University Hospital | 2025-03-11 |
| AD1208 in Subjects With Any Progressive, Locally Advanced or Metastatic Solid Tumors (NCT06911333) | Avelos Therapeutics Inc. | 2025-03-11 |
| A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer (NCT06879041) | AstraZeneca | 2025-03-10 |
| Oral Deucrictibant for Prophylactic and Acute Treatment in Hereditary Angioedema Patients (NCT07046806) | Institute for Asthma and Allergy | 2025-03-10 |
| A Study of BL0175 Injection in Postmenopausal Female Adults With HR-positive, Locally Advanced or Metastatic Cancer (NCT06738966) | Shanghai Best-Link Bioscience, LLC | 2025-03-10 |
| A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies (NCT06528301) | Umoja Biopharma | 2025-03-10 |
| Safety and Preliminary Efficacy of SA53-OS in Patients With Locally Advanced or Metastatic Solid Tumors (NCT06578624) | Lamassu Bio Inc | 2025-03-10 |
| A Study to Compare PK Characteristics and Safety Profiles Between AD-228B and AD-2284 (NCT06884098) | Addpharma Inc. | 2025-03-10 |
| A Study of Suzetrigine (SUZ) Spray-dried Dispersion (SSD) in Healthy Adult Panelists (NCT06834009) | Vertex Pharmaceuticals Incorporated | 2025-03-10 |
| A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO) (NCT06789445) | BlueRock Therapeutics | 2025-03-10 |
| Postoperative Adjuvant Therapy for CT041 Gastric or Gastroesophageal Junction (G/GEJ) Adenocarcinoma Patients (NCT06857786) | Peking University | 2025-03-10 |
| A Study to Assess New Formulations of TEV-56286 (NCT06911567) | Teva Branded Pharmaceutical Products R&D LLC | 2025-03-10 |
| Study of 225Ac-ABD147 to Establish Optimal Dose in Patients With SCLC and LCNEC of the Lung That Previously Received Platinum-based Chemotherapy (NCT06736418) | Abdera Therapeutics Inc. | 2025-03-10 |
| A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease (NCT06925542) | CRISPR Therapeutics | 2025-03-10 |
| Personalized Ultrasonic Brain Stimulation for Depression (R61) (NCT06902298) | Brian Mickey | 2025-03-10 |
| A Study of SPY003-207 in Healthy Volunteers (NCT06873724) | Spyre Therapeutics, Inc. | 2025-03-10 |
| A Study to Evaluate the Safety, Tolerability and PK of SK-08 (NCT07021157) | Consun Pharmaceutical Group | 2025-03-09 |
| Bioequivalence Assessment Between Two Imeglimin Hydrochloride Film Coated Tablet Formulations (NCT07127094) | Aya Mohammed Abdel Magid Abdel Hamid | 2025-03-09 |
| To Compare and Evaluate the Oral Bioavailability of Empagliflozin + Linagliptin 10 mg/5 mg Filmcoated Tablets With That of Glyxambi 10 mg/ 5 mg Film-coated Tablets in Healthy, Adult, Human Subjects Under Fasting Conditions. (NCT07039890) | Humanis Saglık Anonim Sirketi | 2025-03-08 |
| Efficacy And Safety Of Azithromycin To Achieve Remissionin In Children With Steroid Sensitive Nephrotic Syndrome (NCT07320612) | University of Child Health Sciences and Children's Hospital, Lahore | 2025-03-08 |
| Study of YK012 in Primary Membranous Nephropathy (NCT06982729) | Excyte Biopharma Ltd | 2025-03-08 |
| A Varegacestat Hepatic Impairment Study (NCT06841315) | Immunome, Inc. | 2025-03-07 |
| A Chatbot To Support Substance Use Recovery (NCT06845878) | Dimagi Inc. | 2025-03-07 |
| A Phase I Study Investigating the Combination of the Menin Inhibitor Ziftomenib With Venetoclax and Gemtuzumab in Pediatric Patients With Acute Myeloid Leukemia (NCT06448013) | M.D. Anderson Cancer Center | 2025-03-07 |
| A Trial to Test the Effects of Other Drugs on SEP-380135 in Healthy Men and Women (NCT07305779) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2025-03-07 |
| A Phase Ia/Ib Clinical Study of GH56 Capsules in Subjects With MTAP-Deleted Advanced Solid Tumors (NCT06796699) | Suzhou Genhouse Bio Co., Ltd. | 2025-03-07 |
| A Trial to Evaluate KPC000154 Tablets in Healthy Subjects (NCT06867406) | Kunming Pharmaceuticals, Inc. | 2025-03-07 |
| Using Novel Imaging to More Safely Treat Neuroendocrine Tumors (NCT06122610) | University of Wisconsin, Madison | 2025-03-07 |
| Intrathecal Combination of Programmed Death-1 (PD-1)/Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4) Bispecific Antibody and Pemetrexed for Leptomeningeal Metastasis (NCT06762080) | Guangzhou Medical University | 2025-03-07 |
| Induced Pluripotent Stem Cells-derived Small Extracellular Vesicles May Promote Neurological Function and Improve Cognitive Impairment in Acute Ischemic Stroke Patients (NCT07145294) | Hongmei Wang | 2025-03-07 |
| Phase 1 to Investigate the Safety, Tolerability, and Efficacy of GCC2005 in Patients With R/R NK and T-cell Malignancies (NCT06699771) | GC Cell Corporation | 2025-03-07 |
| Study of PN20 in Adult Patients With Primary Immune Thrombocytopenia (ITP) (NCT06880081) | Chongqing Peg-Bio Biopharm Co., Ltd. | 2025-03-07 |
| A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer (NCT06521567) | GlaxoSmithKline | 2025-03-06 |
| Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations (NCT06772623) | AbbVie | 2025-03-06 |
| Safety, Tolerability, and Pharmacokinetics of ACT500 in Healthy Adult Participants (NCT06716905) | Xiamen Amoytop Biotech Co., Ltd. | 2025-03-06 |