| Phage Therapy for the Treatment of a Chronic Enterococcus Faecium Periprosthetic Joint Infection (NCT06942624) | Orthopaedic Innovation Centre | 2025-05-01 |
| Application of VascuLens 2.0, A Mixed Reality System for Surgical Guidance During DIEP Flap Harvest (NCT07080463) | University of British Columbia | 2025-05-01 |
| This Study is to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of HSK47388 in Healthy Volunteers (NCT06926218) | Haisco Pharmaceutical Group Co., Ltd. | 2025-05-01 |
| PIRATES: Image-guided Hyper-fractioned Dose-escalation With Proton Therapy for Head and Neck Cancer (NCT06446713) | University Medical Center Groningen | 2025-05-01 |
| S095033 in Combination With Paclitaxel as 2nd- or 3rd-line Treatment in Participants With Advanced or Metastatic ESCC (NCT05312372) | Institut de Recherches Internationales Servier | 2025-05-01 |
| A Study to Learn About the Study Medicine Called PF-08046031 in Advanced Melanoma and Other Solid Tumors (NCT06799533) | Pfizer | 2025-05-01 |
| A Bioequivalence Study of Two Different Processes of PEG-rhGH Preparations (NCT06840691) | Changchun GeneScience Pharmaceutical Co., Ltd. | 2025-05-01 |
| A First-in-human Study of KY-0301 in Patients With Advanced Solid Tumors. (NCT06928363) | Novatim Immune Therapeutics (Zhejiang) Co., Ltd. | 2025-05-01 |
| Intervention Evaluation WEH (Women Who Have Experienced Homelessness) (NCT06570525) | Rush University Medical Center | 2025-05-01 |
| Dexmedetomidine Added to Bupivacaine for ESP Block in Children Undergoing Lower Abdominal Surgeries (NCT07023991) | Ain Shams University | 2025-05-01 |
| A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis. (NCT06916806) | AstraZeneca | 2025-05-01 |
| The PROOV Study: Exploiting the Synergistic Effect of PARP Inhibition With Cisplatin and Hyperthermia During Interval Cytoreductive Surgery and HIPEC in Ovarian Cancer (NCT07460180) | The Netherlands Cancer Institute | 2025-05-01 |
| Ultrasound Guided Emergency Physician Performed Erector Spinae Nerve Block for Rib Fracture Analgesia (NCT04168710) | Yale University | 2025-05-01 |
| Genetically Modified T Cells Against Ovarian Cancer (NCT03184753) | Shenzhen Geno-Immune Medical Institute | 2025-05-01 |
| CD73/AXL Targeted HypoSti.CAR-T Cells in CD73/AXL Positive Advanced/Metastatic Solid Tumors (NCT06939270) | Chinese PLA General Hospital | 2025-05-01 |
| Effectiveness and Safety of Limbal Relaxing Incisions for Correcting Post Phacoemulsification High Astigmatism (NCT06896357) | Assiut University | 2025-05-01 |
| The Food Effect on PK Characteristics and Safety Profiles of PA-111 (NCT06976489) | Addpharma Inc. | 2025-05-01 |
| A Study of XB628 Alone and in Combination With Zanzalintinib in Participants With Recurrent Advanced or Metastatic Solid Tumors (NCT06952010) | Exelixis | 2025-05-01 |
| CREATE - Cabotegravir & Rilpivirine Antiretroviral Therapy in Pregnancy (NCT06336434) | National Institute of Allergy and Infectious Diseases (NIAID) | 2025-05-01 |
| Clinical Trial of HRS-4642 Plus SHR-A2102 in Patients With Advanced Solid Tumors (NCT06955390) | Henan Cancer Hospital | 2025-05-01 |
| Relative Bioavailability Study to Evaluate Cetirizine HCl Gummy 10 mg and Cetirizine HCl Oral Tablets 10 mg (NCT04071821) | Seattle Gummy Company | 2025-05-01 |
| Phase 1 Study of AUTX-703 in Relapsed/Refractory AML and MDS (NCT06846606) | Auron Therapeutics, Inc. | 2025-05-01 |
| Impact of Sodium Bicarbonate on 24-hour Urine Parameters in Hypocitriuric and Uric Acid Stone Formers (NCT06335537) | University of California, Irvine | 2025-05-01 |
| Behavioral Pharmacology of Cannabis in Older Adults (NCT06055309) | University of Arkansas | 2025-05-01 |
| A Study of LY4268989 (MORF-057) in Healthy Participants (NCT06964776) | Eli Lilly and Company | 2025-05-01 |
| Study on GD2 Positive Solid Tumors by 4SCAR-GD2 (NCT02992210) | Shenzhen Geno-Immune Medical Institute | 2025-05-01 |
| JS111 in Patients With Advanced NSCLC Harboring EGFR Mutations (NCT06940401) | Suzhou Junjing BioSciences Co., Ltd. | 2025-04-30 |
| Age-dependent Effects of Smoked and Oral Delta-9-THC (NCT05865470) | University of California, Los Angeles | 2025-04-30 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s) (NCT06884618) | Hoffmann-La Roche | 2025-04-30 |
| Disitamab Vedotin Combined With Ivonescimab in Cisplatin-Ineligible Muscle-Invasive Bladder Cancer (NCT06957561) | Sun Yat-sen University | 2025-04-30 |
| First-In-Human Study in Participants With Advanced Solid Tumors (NCT06885645) | Chengdu Kanghong Biotech Co., Ltd. | 2025-04-30 |
| Evaluating Gingivitis and Systemic Biomarkers (NCT06962956) | Procter and Gamble | 2025-04-30 |
| Viral Specific T-Lymphocytes to Treat Infection With Adenovirus, Cytomegalovirus or Epstein-Barr Virus in Patients With Compromised Immunity (NCT06909110) | Jessie L. Alexander | 2025-04-30 |
| Study to Evaluate LPH-5 in Healthy Subjects (NCT06722820) | Lophora | 2025-04-30 |
| A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases (NCT06626919) | Arcellx, Inc. | 2025-04-30 |
| Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies (NCT07064018) | University of California, Irvine | 2025-04-30 |
| A First in Human Study of CMND-100 in Healthy and Alcohol Use Disorder (AUD) Subjects (NCT05913752) | Clearmind Medicine Inc. | 2025-04-30 |
| A Study of Sirolimus (Albumin-Bound) in Combination With Palbociclib and Fulvestrant for the Treatment of Advanced Breast Cancer (NCT06941142) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2025-04-30 |
| Whole Heart Radiotherapy for End-stage Heart Failure (NCT06299176) | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2025-04-30 |
| Clinical Trial of CD38 Monoclonal Antibody Combined With Chemotherapy for T-Cell Acute Lymphoblastic Leukemia (NCT07585734) | Institute of Hematology & Blood Diseases Hospital, China | 2025-04-30 |
| A Study of PARP1 Selective Inhibitor, EIK1004 (IMP1707) in Participants With Advanced Solid Tumors. (NCT06907043) | Eikon Therapeutics | 2025-04-30 |
| A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer (NCT06926920) | Gilead Sciences | 2025-04-30 |
| A Bioavailability Study of GS1-144 Tablets in Healthy Postmenopausal Women (NCT06983925) | Changchun GeneScience Pharmaceutical Co., Ltd. | 2025-04-30 |
| To Compare and Evaluate the Oral Bioavailability of Bilastine 20 mg Orally Dispersible Tablet With That of Bilaxten (Bilastine) 20 mg Orally Dispersible Tablet in Healthy, Adult, Human Subjects Under Fasting Conditions (NCT07042828) | Humanis Saglık Anonim Sirketi | 2025-04-30 |
| A Study of AK130 in Combination With AK112 for the Treatment of Advanced Biliary Tract Cancer (NCT06938321) | Akeso | 2025-04-30 |
| IBI343 Combined With Chemotherapy in Advanced Pancreatic Cancer (NCT07692750) | Zhejiang Cancer Hospital | 2025-04-30 |
| Mesothelin and Claudin 18.2 Dual-Target CAR-T Therapy in Advanced Pancreatic Cancer (NCT07066995) | Essen Biotech | 2025-04-29 |
| A Phase 1 Study of SYNCAR-001 + STK-009 Without Conditioning Chemotherapy (Lymphodepletion) in Subjects With Severe, Refractory Systemic Autoimmune Rheumatic Disease (NCT06544330) | Synthekine | 2025-04-29 |
| Study for AZD4360 in Participants With Advanced Solid Tumours (NCT06921928) | AstraZeneca | 2025-04-29 |
| Sequential CD146 and GPC3 CAR-T Cell Therapy in Advanced Ovarian Cancer (NCT07067255) | Essen Biotech | 2025-04-29 |
| Adjuvant Concurrent Immunotherapy and Radiotherapy for the Treatment of Bladder Cancer (NCT06586255) | Abramson Cancer Center at Penn Medicine | 2025-04-29 |
| Sequential CAR-T Cells Targeting BCMA/GPRC5D in Patients With Relapsed/ Refractory Multiple Myeloma (NCT07032129) | Essen Biotech | 2025-04-29 |
| Safety, Tolerability, and Pharmacokinetics of KarXT and Dual-burst Release of Xanomeline With Immediate-release Trospium Chloride in Adolescents With Psychiatric Disorders (NCT06853171) | Bristol-Myers Squibb | 2025-04-29 |
| An Investigational Study of ESK-001 in Participants With Normal Liver Function and Participants With Mild, Moderate, and Severe Liver Damage (NCT06952634) | Alumis Inc | 2025-04-29 |
| Study of IBI3020 Treatment in Participants With Late-Stage Solid Tumors (NCT06963281) | Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD. | 2025-04-29 |
| SGLT2i, Ketoacidosis, Volume Contraction, and Insulinopenia (NCT07053306) | The University of Texas Health Science Center at San Antonio | 2025-04-29 |
| A Study in Healthy People to Test Whether Erythromycin Influences the Amount of BI 1291583 in the Blood (NCT06917872) | Boehringer Ingelheim | 2025-04-29 |
| Anti-CD7 CAR-T Cells in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia or Lymphoma (NCT06934382) | Stephan Grupp MD PhD | 2025-04-29 |
| Treating Parkinson's Disease Through Transplantation of Autologous Stem Cell-Derived Dopaminergic Neurons (NCT06687837) | Jeffrey S. Schweitzer, MD, PhD | 2025-04-29 |
| CD19-CD22-Bispecific Chimeric Antigen Receptor (CAR) T Cell Therapy for Pediatric Patients With Acute Lymphoblastic Leukemia (NCT06777979) | St. Jude Children's Research Hospital | 2025-04-28 |
| A Study to Evaluate ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease or With Metabolic Dysfunction-Associated Steatohepatitis (MASLD/MASH) (NCT06836609) | Regeneron Pharmaceuticals | 2025-04-28 |
| A Study of Carbamazepine (CBZ) and MK-8527 in Healthy Adult Participants (MK-8527-012) (NCT06893081) | Merck Sharp & Dohme LLC | 2025-04-28 |
| Clinical Study on Chimeric Antigen Receptor T Lymphocyte (CAR-T) Targeting CEA for the Treatment of CEA - Positive Advanced Lung Cancer (NCT06945523) | Chongqing Precision Biotech Co., Ltd | 2025-04-28 |
| Evaluating the Dose, Safety, Tolerability, and Immunogenicity of Mosaic Hexavalent Influenza Vaccine VRCFLUMOS0116-00-VP (FluMos-v2) With and Without ALFQ Adjuvant in Healthy Adults (NCT06863142) | National Institute of Allergy and Infectious Diseases (NIAID) | 2025-04-28 |
| A Phase 1 Clinical Study to Evaluate the Effects of SHR7280 on the Pharmacokinetics of Midazolam, S-warfarin, Omeprazole, Digoxin, and Rosuvastatin in Healthy Subjects (NCT06949124) | Jiangsu HengRui Medicine Co., Ltd. | 2025-04-28 |
| 131I-apamistamab-based Conditioning for Hematopoietic Stem Cell Transplant (HSCT) in Advanced Sickle Cell Disease (SCD) (NCT07015684) | Columbia University | 2025-04-28 |
| The Pharmacokinetics (PK), Safety, Tolerability of SR750 (Formulation F1) in Healthy Volunteers (NCT06932536) | Shanghai SIMR Biotechnology Co., Ltd. | 2025-04-28 |
| A Study to Assess the Safety and Tolerability, and Pharmacokinetics of UCB0022 in Healthy Caucasian, Japanese, and Chinese Participants (NCT06970301) | UCB Biopharma SRL | 2025-04-28 |
| Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SNA02-48 Injection in Chinese Adult Participants (NCT06939777) | Sinovac Life Sciences Co., Ltd. | 2025-04-28 |
| A Trial to Evaluate the Safety and Efficacy of NCR102 in Subjects With aGVHD (NCT06941350) | Nuwacell Biotechnologies Co., Ltd. | 2025-04-28 |
| A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (NCT06624085) | Hoffmann-La Roche | 2025-04-28 |
| Evaluating BL-M14D1 in Subjects With Locally Advanced or Metastatic Small Cell Lung Cancer and Neuroendocrine Tumors (NCT07080242) | SystImmune Inc. | 2025-04-28 |
| Evaluation of the Concentration of ANT3310 and Meropenem in the Lung in Healthy Adult Participants (NCT06916156) | Antabio | 2025-04-28 |
| Investigating SX-682 in Combination With Apalutamide in Metastatic Castration-resistant Prostate Cancer (NCT07002320) | Institute of Cancer Research, United Kingdom | 2025-04-28 |
| Eganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML (NCT06533761) | Stelexis BioSciences | 2025-04-28 |
| Tracing the Metabolic Flux of Orally Administered NAD+ Precursors (NCT06882096) | Metro International Biotech, LLC | 2025-04-28 |
| A Clinical Trial to Evaluate the Relative Bioavailability of PRAX-628 (NCT06840925) | Praxis Precision Medicines | 2025-04-28 |
| Lead-212 PSV359 Therapy for Patients With Solid Tumors (NCT06710756) | Perspective Therapeutics | 2025-04-28 |
| A Study to Learn How Different Tablets of the Study Medicine Mevrometostat Are Taken up Into the Blood in Healthy Adults (NCT06661694) | Pfizer | 2025-04-28 |
| A Phase I Clinical Study of SSS59 Monotherapy in Patients With Advanced Malignant Tumors (NCT06944444) | Shenyang Sunshine Pharmaceutical Co., LTD. | 2025-04-27 |
| Phase I Clinical Study of YK1101 Injection for the Treatment of Advanced Solid Tumors (NCT07139067) | Peking University | 2025-04-27 |
| Secretin in Ex-situ Liver Perfusion (NCT07651748) | Erasmus Medical Center | 2025-04-26 |
| Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors (NCT06414460) | InSilico Medicine Hong Kong Limited | 2025-04-25 |
| Study of BCMA/CD70 CAR-T Therapy for Refractory cSLE (NCT06934447) | The Children's Hospital of Zhejiang University School of Medicine | 2025-04-25 |
| IOMAB-CAR-T Followed by CAR-T Cell Therapy in R/R DLBCL (NCT06768905) | University of Texas Southwestern Medical Center | 2025-04-25 |
| First-in-Human Single and Multiple Dose of HL-400 (NCT06997484) | Highlightll Pharmaceutical (USA) LLC | 2025-04-25 |
| Glumetinib Combined With Fruquintinib in the Treatment of MET Amplification or Protein Overexpression in Third-Line Unresectable Metastatic Colorectal Cancer (NCT06980532) | Liu Huang | 2025-04-25 |
| Analgesic Effect of Bupivacaine Plus Ketamine Versus Bupivacaine Alone in Transversalis Fascia Plane Block (NCT06935669) | Ain Shams University | 2025-04-25 |
| A Study of ERAS-601 in People With Chordoma (NCT06957327) | Memorial Sloan Kettering Cancer Center | 2025-04-25 |
| SHR-A1811 Combination Regimen for the Treatment of Recurrent or Metastatic Cervical Cancer (NCT06859775) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2025-04-25 |
| Safety and Efficacy of Anlotinib in the Treatment of Recurrent Craniopharyngioma (NCT06970145) | Nanfang Hospital, Southern Medical University | 2025-04-25 |
| Efficacy of Fuzheng Tongfu Jiedu Prescription for Treating Gastrointestinal Dysfunction Associated With Sepsis (NCT06933238) | Dongzhimen Hospital, Beijing | 2025-04-25 |
| A Clinical Trial of Human Umbilical Cord Mesenchymal Stem Cell Injection for the Treatment of Severe Acute Respiratory Distress Syndrome (NCT07413978) | Changchun Tuohua Pharmaceutical Co., Ltd. | 2025-04-25 |
| Cell Therapy for Corneal Endothelial Cell Dysfunction (NCT06726174) | National Taiwan University Hospital | 2025-04-25 |
| A Study of BR111 in Patients With Advanced Malignancies (NCT06937957) | BioRay Pharmaceutical Co., Ltd. | 2025-04-24 |
| A Trial of HRS-6768 in Patients With Advanced Solid Tumors (NCT06925581) | Jiangsu HengRui Medicine Co., Ltd. | 2025-04-24 |
| A Phase I/II of HRS-6719 in Patients With Advanced/Metastatic Solid Tumors (NCT06922357) | Shandong Suncadia Medicine Co., Ltd. | 2025-04-24 |
| Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations (NCT06915753) | Tyra Biosciences, Inc | 2025-04-24 |
| A Phase I Study to Evaluate GFS202A in Advanced Solid Tumor Patients With Pre-cachexia or Cachexia (NCT06898255) | Genfleet Therapeutics (Shanghai) Inc. | 2025-04-24 |
| A Phase I Study of SIM0388 in Participants With Malignant Ascites. (NCT07007988) | Jiangsu Simcere Pharmaceutical Co., Ltd. | 2025-04-24 |