| Phase 1 Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TRT-448 in Healthy Adult Subjects (NCT07745751) | Trotana, Inc. | 2026-08-30 |
| Clinical Trials of IBI3040 in Healthy Participants and Overweight or Obese Participants (NCT07765160) | Innovent Biologics (Suzhou) Co. Ltd. | 2026-08-30 |
| A Clinical Study on the Efficacy and Safety of Zeprumetostat in Relapsed/Refractory Large Granular Lymphocyte Leukemia (NCT07692529) | Institute of Hematology & Blood Diseases Hospital, China | 2026-08-30 |
| A Phase Ib/II Study of SYS6090 Combination Therapy in Advanced Colorectal Cancer (NCT07750041) | CSPC Megalith Biopharmaceutical Co.,Ltd. | 2026-08-30 |
| A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With HR+, HER2- Advanced Breast Cancer (NCT07310420) | TerSera Therapeutics LLC | 2026-08-30 |
| A Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and the Effect of Food of SYH2056 in Healthy Subjects (NCT07771777) | InnovStone Therapeutics Limited | 2026-08-30 |
| Phase I Study of QLS1510 Tablets in Healthy Participants (NCT07760077) | Shanghai Qilu Pharmaceutical Research and Development Center LTD | 2026-08-30 |
| A Study to Assess Safety and Efficacy of SOT109 in Patients With Advanced Unresectable or Metastatic Colorectal Cancer (NCT07693751) | SOTIO Biotech a.s. | 2026-08-29 |
| Periganglionic Resiniferatoxin for the Treatment of Intractable Pain Due to Cancer-induced Bone Pain (NCT02522611) | National Institute of Neurological Disorders and Stroke (NINDS) | 2026-08-27 |
| DAREON®-36: A Study to Test Obrixtamig in Combination With ZL-1310 in People With Advanced Small Cell Lung Cancer or Other Neuroendocrine Cancers (NCT07707895) | Boehringer Ingelheim | 2026-08-26 |
| A Clinical Trial of Multiple Formulations of MK-4082 in Healthy Overweight and Obese Participants (MK-4082-007) (NCT07748351) | Merck Sharp & Dohme LLC | 2026-08-25 |
| A Phase 1 Study of FXR0906 in Healthy Adults With or Without Elevated Triglycerides (NCT07766759) | Fosun Pharmaceutical Industrial Development (Shenzhen) Co., Ltd. | 2026-08-25 |
| A Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of INS1033 in Healthy Participants (NCT07765706) | Insmed Incorporated | 2026-08-25 |
| An Open Label Dose Escalation Study of VY1706 in Participants With Early Alzheimer's Disease (NCT07764146) | Voyager Therapeutics | 2026-08-24 |
| Bupropion for Fatigue in End-stage Kidney Disease Patients on Hemodialysis (NCT06609343) | The University of Texas Health Science Center at San Antonio | 2026-08-24 |
| NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors (NCT07664176) | Children's National Research Institute | 2026-08-24 |
| A Study to Evaluate the Pharmacokinetics and Safety of Golcadomide in Participants With Severe Renal Impairment and End-Stage Renal Disease Compared With Participants With Normal Renal Function (NCT07763418) | Bristol-Myers Squibb | 2026-08-24 |
| Combination Therapy (Mirdametinib and Sirolimus) for RAS Mutated Relapsed Refractory Multiple Myeloma (NCT06876142) | National Cancer Institute (NCI) | 2026-08-23 |
| PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI) (NCT07169630) | National Institute of Mental Health (NIMH) | 2026-08-23 |
| Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific Antibodies (NCT06948097) | National Heart, Lung, and Blood Institute (NHLBI) | 2026-08-23 |
| Anti-CRLF2-R/TSLPR Chimeric Antigen Receptor T Cells (TSLPR-CART) in Participants With Recurrent or Refractory CRLF2-R/TSLPR-Overexpressing B-Cell Acute Lymphoblastic Leukemia (B-ALL) (NCT07572136) | National Cancer Institute (NCI) | 2026-08-23 |
| Phase I Open-Label Safety Trial of Pembrolizumab for Neurological Post- Acute Sequelae of SARS-CoV-2 (PD1-PASC I) (NCT07388550) | National Institute of Neurological Disorders and Stroke (NINDS) | 2026-08-23 |
| Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms (NCT06303193) | National Cancer Institute (NCI) | 2026-08-23 |
| Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump Therapy (NCT07715903) | National Cancer Institute (NCI) | 2026-08-23 |
| PET Imaging of Noradrenergic Transmission in the Brain (NCT07686393) | National Institute of Mental Health (NIMH) | 2026-08-23 |
| Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis (NCT07262983) | National Institute of Allergy and Infectious Diseases (NIAID) | 2026-08-23 |
| Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1) (NCT05652504) | National Institute of Allergy and Infectious Diseases (NIAID) | 2026-08-23 |
| Environment and Alcohol: A Pilot Study (NCT06860607) | National Institute on Drug Abuse (NIDA) | 2026-08-23 |
| Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC) (NCT06694454) | National Cancer Institute (NCI) | 2026-08-23 |
| Phase I Trial of High-Density Theta Burst Stimulation (hdTBS) (NCT06868914) | National Institute on Drug Abuse (NIDA) | 2026-08-23 |
| IL-12 Genetically Engineered Myeloid Cells in Participants With Relapsed, Refractory Solid Tumors (NCT07672483) | National Cancer Institute (NCI) | 2026-08-23 |
| Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer (NCT07667400) | National Cancer Institute (NCI) | 2026-08-23 |
| Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease (NCT07509034) | National Cancer Institute (NCI) | 2026-08-23 |
| Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical Carcinoma (NCT06487481) | National Cancer Institute (NCI) | 2026-08-23 |
| Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies (NCT06904066) | National Cancer Institute (NCI) | 2026-08-23 |
| A Study to Assess Adverse Events and How Oral ABBV-932 Moves Through the Body When Given With Oral Itraconazole in Adult Participants With Bipolar Disorder (NCT07071532) | AbbVie | 2026-08-21 |
| Phase 1 Study in Healthy Adults to See How Sevabertinib Changes Metformin Levels in the Body (NCT07753252) | Bayer | 2026-08-21 |
| A Phase I Study to Evaluate the Safety,Pharmacokinetics,Pharmacodynamics,and Efficacy of TJ037130 in Adult Participants With Advanced Solid Tumors (NCT07715747) | TJ Biopharma Co., Ltd. | 2026-08-21 |
| Safety and Pharmacokinetics of Rescue Liposome in Healthy Adults (NCT07375498) | Cristália Produtos Químicos Farmacêuticos Ltda. | 2026-08-20 |
| Effect of Height Based vs Conventional Dose of Spinal Anesthesia in Lower Limb Surgeries (NCT07751835) | Liaquat National Hospital & Medical College | 2026-08-20 |
| Assessing the Efficacy of a High-Dose Lidocaine-Tetracaine Cream for the Treatment of Peripheral Neuropathic Pain (NCT07396129) | Pontificia Universidad Catolica de Chile | 2026-08-20 |
| Testing the Addition of an Anti-Cancer Drug, Glofitamab, to the Usual Chemotherapy Treatment (Alternating R-CHOP/R-DHAP) for Previously Untreated Mantle Cell Lymphoma (NCT07444710) | National Cancer Institute (NCI) | 2026-08-20 |
| Study of ALA-101 in Patients With CD19 Positive Non-Hodgkin Lymphoma and Leukemia. (NCT07518329) | Arovella Therapeutics Ltd | 2026-08-20 |
| Clinical Study to Evaluate the Pharmacokinetics and Safety of CKD-339 in Healthy Volunteers (NCT07748702) | Chong Kun Dang Pharmaceutical | 2026-08-20 |
| A Study to Evaluate Pharmacokinetics of DRL_AB in Healthy Male Participants (NCT07744828) | Dr. Reddy's Laboratories Limited | 2026-08-19 |
| Safety and Immunogenicity Study of a Multivalent Gonorrhoea Vaccine (NCT07758972) | LimmaTech Biologics AG | 2026-08-19 |
| First-in-Human Trial of VBC106 in Participants With Advanced Solid Tumors (NCT07686068) | VelaVigo Bio Inc | 2026-08-18 |
| ENGAGE-TBI Feasibility Study (NCT07549997) | Washington University School of Medicine | 2026-08-17 |
| A Clinical Trial of Nemtabrutinib in Participants With Severe Kidney Disease (MK-1026-027) (NCT07734610) | Merck Sharp & Dohme LLC | 2026-08-17 |
| A Study of V132 in Healthy Older Participants (V132-001) (NCT07712575) | Merck Sharp & Dohme LLC | 2026-08-17 |
| A Study in Healthy People to Measure How Different Doses of Verducatib Affect the Heart (NCT07760246) | Boehringer Ingelheim | 2026-08-17 |
| Safety and Efficacy Study of Sivelestat in Neuromyelitis Optica Spectrum Disorder (NCT07738952) | Kyushu University | 2026-08-17 |
| BRiTE - Bispecific T Cell Engager for Patients With Glioblastoma (NCT04903795) | Mustafa Khasraw, MBChB, MD, FRCP, FRACP | 2026-08-17 |
| A Study of Ulonivirine (MK-8507) and Methadone in Healthy Volunteers (MK-8507-019) (NCT07595263) | Merck Sharp & Dohme LLC | 2026-08-17 |
| Study to Assess Tolerability of Injecting Larger Volumes (2-5 mL) Subcutaneously at Different Rates: Participant Experience and Acceptance (NCT07769489) | Novo Nordisk A/S | 2026-08-17 |
| A Study to Investigate Safety, Reactogenicity, and Immunogenicity of mRNA-1365 (Profile 2) in Older Healthy Adults (NCT07764237) | ModernaTX, Inc. | 2026-08-16 |
| A First-in-Human Study of ZE66-0205 in Healthy Volunteers (NCT07735728) | Eilean Therapeutics | 2026-08-15 |
| High-energy Human Milk Diets in the First Two Weeks After Birth to Reduce BPD in Extremely Preterm Infants (NCT07307612) | University of Alabama at Birmingham | 2026-08-15 |
| A Phase I/II Study of Eque-cel in Subjects Withimmune-mediated Necrotizing Myopathy (NCT07752264) | Nanjing IASO Biotechnology Co., Ltd. | 2026-08-15 |
| A Clinical Study of GO321 in Patients With Advanced Solid Tumors (NCT07748117) | GeneSail Biotech (Shanghai) Co., Ltd. | 2026-08-15 |
| A Pan-RAS Inhibitor in Combination With Anti-Tumor Therapy in Participants With Advanced Pancreatic Cancer (NCT07736612) | Zhejiang University | 2026-08-15 |
| A Safety, Reactogenicity and Immunogenicity Trial of RVX-sCPD9 Booster Intranasal COVID-19 Vaccine (NCT07703475) | National Institute of Allergy and Infectious Diseases (NIAID) | 2026-08-15 |
| A Study of ONO-4538HSC in Pediatric Patients With Malignant Solid Tumors and in Patients With Epithelioid Sarcoma. (NCT07734116) | Ono Pharmaceutical Co., Ltd. | 2026-08-15 |
| Aging and Task-specific Training to Reduce Falls (NCT07094659) | University of Illinois at Chicago | 2026-08-15 |
| Study of 203Pb-RMX-VH-PIB Dosimetry and Biodistribution in Patients With Glioblastoma Multiform (GBM) and Pancreatic Ductal Adenocarcinoma (PDAC) (NCT07733674) | Radiomedix, Inc. | 2026-08-15 |
| Pharmacokinetics of Zoledronic Acid in Patients on Dialysis (NCT07741136) | University of Campinas, Brazil | 2026-08-15 |
| Dietary Arginine Deprivation Combined With Chemoradiotherapy for Neoadjuvant Treatment of Rectal Cancer: A Randomized Controlled Trial (NCT07755124) | West China Hospital | 2026-08-14 |
| A Study to Assess Potential Drug-Drug Interactions of E2086 in Healthy Participants (NCT07766369) | Eisai Inc. | 2026-08-12 |
| A First-in-human Research Study on How NNC0721-8060 Works in People Living With Overweight or Obesity (NCT07767175) | Novo Nordisk A/S | 2026-08-12 |
| Evaluation of Intra-articular CX-011 to Treat Moderate to Severe Pain From Knee Osteoarthritis (NCT07308834) | CarthroniX, Inc. | 2026-08-11 |
| A Study of QLS2404 Injection in Healthy Participants and Participants With Rheumatic Autoimmune Diseases (NCT07751315) | Qilu Pharmaceutical Co., Ltd. | 2026-08-11 |
| A Phase 1 Study of BPX-601 CAR T-Cell Therapy in Adult Participants With Prostate Cancer That Has Returned, is Resistant to Treatment and Has Spread (NCT07543055) | Regeneron Pharmaceuticals | 2026-08-10 |
| Pre-emptive Insulin to Prevent High Glucose After a Knee Steroid Injection in Adults With Type 2 Diabetes (NCT07757464) | Shifa International Hospital | 2026-08-10 |
| Efficacy and Safety Of Fractional Carbon Dioxide Laser Plus Topical Metformin In Treatment Of Acanthosis Nigricans (NCT07760181) | Al-Azhar University | 2026-08-10 |
| A Study to Investigate the Safety and Tolerability of Multiple Study Interventions in Participants With Moderate to Severe Ulcerative Colitis (NCT07747467) | GlaxoSmithKline | 2026-08-10 |
| A Sub Study to Investigate the Safety and Tolerability of Aletekitug in Participants With Moderate To Severe Ulcerative Colitis (NCT07747480) | GlaxoSmithKline | 2026-08-10 |
| NORTHERA (DROXIDOPA) for Dysautonomia in Pediatric Survivors of Menkes Disease (NCT07398508) | Stephen G. Kaler | 2026-08-10 |
| Photodynamic Therapy For Onychomycosis (NCT07756671) | The University of Texas Health Science Center, Houston | 2026-08-10 |
| A Study of HW243040 in Healthy Participants (NCT07737496) | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. | 2026-08-10 |
| Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer (NCT07147231) | National Cancer Institute (NCI) | 2026-08-10 |
| A Study to Evaluate Sequential Administration of Injections of AGN-151586 Followed by BOTOX in Adult Participants for Treatment of Glabellar Lines (NCT07756580) | AbbVie | 2026-08-10 |
| A Trial Evaluating Safety, Tolerability and Efficacy of CTX340 in Participants With Hypertension (NCT07758634) | CRISPR Therapeutics AG | 2026-08-08 |
| NAD Augmentation to Prevent or Reverse Alzheimer's Disease in People With Down Syndrome (NCT07278492) | Brigham and Women's Hospital | 2026-08-07 |
| Phase 1 Challenge Study Using rDEN2delta30-7169 to Evaluate Host-Pathogen Interactions in Primary, Homotypic, and Heterotypic Dengue Virus Infection (NCT07706686) | National Institute of Allergy and Infectious Diseases (NIAID) | 2026-08-07 |
| A Phase 1 Trial of AMG 691 in Healthy Chinese and Japanese Volunteers (NCT07745907) | Amgen | 2026-08-07 |
| Study of LNP.UCD.ABE in Patients With Urea Cycle Disorders (NCT07667387) | Rebecca Ahrens-Nicklas | 2026-08-07 |
| Bioequivalence Study of AJU-C715 and C715R in Healthy Adult Volunteers (NCT07581028) | AJU Pharm Co., Ltd. | 2026-08-07 |
| Study to Compare the Plasma Concentration of Belumosudil Given as an Oral Suspension and as a Tablet to Healthy Adult Male Participants (NCT07726914) | Sanofi | 2026-08-06 |
| First-in-Human Trial of DS1025a in Participants With Advanced Solid Tumors (NCT07681882) | Daiichi Sankyo | 2026-08-06 |
| Psilocybin to Treat Depression in Spinal Cord Injury (NCT07251491) | James J. Peters Veterans Affairs Medical Center | 2026-08-06 |
| ACT201 Injection in Healthy Participants and Participants With Chronic Hepatitis B (CHB) (NCT07741461) | Xiamen Amoytop Biotech Co., Ltd. | 2026-08-06 |
| A Study in Healthy People to Compare Two Tablet Formulations of Pramipexole (NCT07727785) | Boehringer Ingelheim | 2026-08-05 |
| QT Interval Effects Study of Oral FXS5626 Tablets (NCT07695779) | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. | 2026-08-05 |
| A Study to Assess the Pharmacokinetics, Safety and Tolerability of Single-dose Adagrasib (BMS-986503) in Healthy Participants of Japanese Descent (NCT07723118) | Mirati Therapeutics Inc. | 2026-08-05 |
| A Study of the Safety, Tolerability, Pharmacokinetics and Efficacy of KIT2014 in Patients With Moderate to Severe COPD (NCT07668518) | Kither Biotech Srl | 2026-08-05 |
| Safety And Tolerability Of Gamma Glutamylcysteine (GGC) Oral Supplementation In MCI Patients (NCT07583251) | Pravat Mandal | 2026-08-04 |
| An Open-Label Pharmacokinetic Study for Patients With Actinic Keratosis on the Upper Extremities or the Face (NCT07729579) | Sun Pharmaceutical Industries Limited | 2026-08-04 |
| SLR-108 PET Imaging in Subjects With Metastatic Solid Tumors (NCT07728942) | Solve Therapeutics | 2026-08-04 |
| Alpha-0261 Tablets for Moderate-to-Severe Ulcerative Colitis (NCT07744646) | The First Affiliated Hospital of Anhui Medical University | 2026-08-03 |
| A Study Investigating the Safety of RO7795081 and How the Body Processes RO7795081 in People With Normal or Decreased Kidney Functions (NCT07741604) | Hoffmann-La Roche | 2026-08-03 |