| An Extension Study to Evaluate the Long-Term Efficacy and Safety of BMN 190 in Patients With CLN2 Disease (NCT02485899) | BioMarin Pharmaceutical | 2015-02-01 |
| Traumatic Optic Neuropathy Treatment Trial (TONTT) (NCT01783847) | Tehran University of Medical Sciences | 2015-02-01 |
| Polyethylene Glycol Loxenatide Pharmacokinetics Study in Subjects With Normal and Insufficiency Renal Function (NCT02467790) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2015-02-01 |
| A Single Ascending Dose Study of ACT-541468 in Healthy Male Subjects (NCT02919319) | Idorsia Pharmaceuticals Ltd. | 2015-02-01 |
| A Study to Assess the Relative Bioavailability of Process Variants of Selumetinib in Healthy Male Volunteers (NCT02322749) | AstraZeneca | 2015-02-01 |
| CKD-828 (80/5mg) Pharmacokinetic Study (NCT02358824) | Chong Kun Dang Pharmaceutical | 2015-02-01 |
| Comparative Evaluation of Pharmacokinetics and Safety of BCD-055 and Remicade in Patients With Ankylosing Spondylitis (NCT02359903) | Biocad | 2015-02-01 |
| Testing the Interactive Effects of Delta-9-Tetrahydrocannabinol and Pregnenolone (NCT02576912) | Yale University | 2015-02-01 |
| The Improving Effect of Autologous Stromal Vascular Fraction (SVF) in Adipose Tissue on Skin Grafting (NCT02546882) | Shanghai Jiao Tong University School of Medicine | 2015-02-01 |
| A Phase I/II Double-blind Safety and Efficacy Evaluation of Nowarta110 in Patients With Plantar Warts (NCT02338336) | Nowarta Biopharma Inc | 2015-02-01 |
| A Study of Allogeneic Human UC-MSC and Liberation Therapy (When Associated With CCSVI) in Patients With RRMS (NCT02418325) | Genesis Limited | 2015-02-01 |
| Pharmacokinetics of Intranasal Ketorolac in Children (NCT02297906) | Columbia University | 2015-02-01 |
| Whole Blood Bactericidal Activity (WBA) Against Mycobacterium Tuberculosis of Faropenem Plus Amoxicillin/Clavulanic Acid in Healthy Volunteers (NCT02393586) | National University Hospital, Singapore | 2015-02-01 |
| Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases (NCT02231710) | Bellicum Pharmaceuticals | 2015-02-01 |
| Cannabinoids, Learning, and Memory (NCT02407808) | Yale University | 2015-02-01 |
| Safety and Efficacy of a PIKA Rabies Vaccine Containing the PIKA Adjuvant (NCT02657161) | Yisheng Biopharma (Singapore) Pte. Ltd. | 2015-02-01 |
| Study to See How Safe Curcumin is and How Well it Works When Used to Treat Mucositis in Patients Getting Chemotherapy (NCT02300727) | Amy Beres | 2015-02-01 |
| Clinical Pharmacology Study to Evaluate the Total Systemic Exposure and Lung Bioavailability of CHF 5993 pMDI Combination in Healthy Volunteers (NCT02359292) | Chiesi Farmaceutici S.p.A. | 2015-02-01 |
| Study to Evaluate the Safety and Immunogenicity of 'IL-YANG Flu Vaccine Quadrivalent Inj' in Healthy Korean Adults (NCT02480998) | Il-Yang Pharm. Co., Ltd. | 2015-02-01 |
| Study Evaluating Safety, Tolerability, and PK of Multiple Ascending Doses of GC021109 in Subjects With Mild to Moderate Alzheimer's Disease (NCT02386306) | GliaCure, Inc. | 2015-02-01 |
| F901318 Multiple Ascending Dose Study (NCT02342574) | F2G Ltd | 2015-02-01 |
| Comparative Bioavailability Study of UDCA (NCT02385032) | Daewoong Pharmaceutical Co. LTD. | 2015-02-01 |
| Icosabutate - A Phase I, Single Oral Dose, Safety, Tolerability and Pharmacokinetic Study in Healthy Subjects (NCT02364635) | Pronova BioPharma | 2015-02-01 |
| Phase 1/2 Study of TAK-850 Intramuscular Injection in Healthy Pediatric Participants (NCT02367885) | Takeda | 2015-02-01 |
| Length of Effect of Extended Release Aspirin on Platelets in Patients With Diabetes and Heart Disease (NCT02370680) | New Haven Pharmaceuticals, Inc. | 2015-02-01 |
| Botox Injection in Treatment of Chronic Migraine (NCT02259075) | Norwegian University of Science and Technology | 2015-02-01 |
| Study of Kinetics, Dosimetry & Safety of [18F]F-AraG, a Positron Emission Tomography Imaging Tracer in Healthy Humans (NCT02323893) | CellSight Technologies, Inc. | 2015-02-01 |
| Drug-Drug Interaction Study: ASP2151 and Bupropion (NCT02369172) | Maruho Europe Limited | 2015-02-01 |
| Low Dose IL-2 for Ulcerative Colitis (NCT02200445) | Scott B. Snapper, MD PHD | 2015-02-01 |
| Bioequivalence of Crushed Stribild With a Normal Breakfast or With Drip Feed Compared to the Whole Tablet (NCT02325934) | Radboud University Medical Center | 2015-02-01 |
| First in Man Evaluation of Single and Multiple Doses of Oral ATX2417 (NCT02316912) | Atopix Therapeutics, Ltd. | 2015-02-01 |
| Modified Diet Trial: A Study of SMT C1100 in Paediatric Patients With DMD Who Follow a Balanced Diet (NCT02383511) | Summit Therapeutics | 2015-02-01 |
| Whole Blood Bactericidal Activity (WBA) Against Mycobacterium Tuberculosis of Rifampicin in Healthy Volunteers (NCT02387242) | National University Hospital, Singapore | 2015-02-01 |
| Safety, Tolerability and PK of Imeglimin in Japanese Volunteers (NCT02373150) | Poxel SA | 2015-02-01 |
| 6-Month Phase I/II Open Label PRTX-100 in Previous Rheumatoid Arthritis Study Participants and Sera Collection (NCT02330445) | Protalex, Inc. | 2015-02-01 |
| Study of CM-24 (MK-6018) Alone and In Combination With Pembrolizumab (MK-3475) in Participants With Selected Advanced or Recurrent Malignancies (MK-6018-001) (NCT02346955) | Famewave Ltd. | 2015-02-01 |
| Bioequivalence Trial of Liquid Versus Freeze-Dried PergoverisĀ® in Pituitary Suppressed Healthy Premenopausal Female Subjects (NCT02317809) | Merck KGaA, Darmstadt, Germany | 2015-01-31 |
| Dose-Ranging Study to Assess the Safety, PK and Initial Antiviral Efficacy of NVR 3-778 in Chronic HBV Patients (NCT02401737) | Novira Therapeutics, Inc. | 2015-01-31 |
| Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors (NCT02143401) | National Cancer Institute (NCI) | 2015-01-30 |
| Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas (NCT02186509) | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 2015-01-30 |
| Single-dose Pharmacokinetics of BMS-626529, Administered as BMS-663068, in Subjects With Hepatic Impairment Compared to Healthy Subjects (NCT02467335) | ViiV Healthcare | 2015-01-29 |
| Neoadjuvant Chemotherapy Followed by Radiation Therapy and Gemcitabine/Sorafenib/Vorinostat in Pancreatic Cancer (NCT02349867) | Virginia Commonwealth University | 2015-01-29 |
| Safety and Biological Activity of Vesatolimod in HIV-1 Infected, Virologically Suppressed Adults (NCT02858401) | Gilead Sciences | 2015-01-29 |
| Phase I Study of Adoptive Immunotherapy With Enriched and Expanded Autologous Natural Killer (NK) Cells for Patients With Ph+ Acute Lymphoblastic Leukemia (ALL) (NCT02185781) | Gruppo Italiano Malattie EMatologiche dell'Adulto | 2015-01-28 |
| Carfilzomib, Rituximab, and Combination Chemotherapy in Treating Patients With Diffuse Large B-Cell Lymphoma (NCT02073097) | Case Comprehensive Cancer Center | 2015-01-28 |
| Genetically Modified Therapeutic Autologous Lymphocytes Followed by Aldesleukin in Treating Patients With Stage III or Metastatic Melanoma (NCT01740557) | M.D. Anderson Cancer Center | 2015-01-28 |
| Analysis of Telmisartan Administered With Antiretroviral Therapy (ART) in Patients With Acute HIV Infection (NCT02170246) | Yale University | 2015-01-28 |
| Assessment of Safety, Tolerability and Pharmacokinetics of Intravitreal Pegcetacoplan (APL-2) for Patients With Wet AMD (NCT02461771) | Apellis Pharmaceuticals, Inc. | 2015-01-28 |
| Pomalidomide in Hereditary Hemorrhagic Telangiectasia and Transfusion-Dependent Vascular Ectasia: a Phase I Study (NCT02287558) | The Cleveland Clinic | 2015-01-27 |
| Clinical Trial of Ebola Vaccines cAd3-EBO, cAd3-EBOZ and MVA-EbolaZ in Healthy Adults in Uganda (NCT02354404) | National Institute of Allergy and Infectious Diseases (NIAID) | 2015-01-27 |
| Phase Ib/2, Multicenter, Dose Escalation Study of DCR-MYC in Patients With Hepatocellular Carcinoma (NCT02314052) | Dicerna Pharmaceuticals, Inc., a Novo Nordisk company | 2015-01-27 |
| Pretargeted Radioimmunotherapy in Metastatic Colorectal Cancer (NCT02300922) | Nantes University Hospital | 2015-01-27 |
| An Investigational Immuno-therapy Study of Ulocuplumab in Combination With Low Dose Cytarabine in Patients With Newly Diagnosed Acute Myeloid Leukemia (NCT02305563) | Bristol-Myers Squibb | 2015-01-27 |
| A Study of Atezolizumab in Combination With Epacadostat in Subjects With Previously Treated Stage IIIB or Stage IV Non-Small Cell Lung Cancer and Previously Treated Stage IV Urothelial Carcinoma (NCT02298153) | Incyte Corporation | 2015-01-27 |
| First in Human Study of M4344 in Participants With Advanced Solid Tumors (NCT02278250) | EMD Serono Research & Development Institute, Inc. | 2015-01-26 |
| Phase I Study MK-3475 With Chemotherapy in Patients With Advanced GI Cancers (NCT02268825) | University of Utah | 2015-01-23 |
| Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission (NCT02140255) | National Institute of Allergy and Infectious Diseases (NIAID) | 2015-01-23 |
| Metformin and Omega-3 Fatty Acids in Woman With a History of Early Stage Breast Cancer (NCT02278965) | Katherine D. Crew | 2015-01-22 |
| A Study of Olaratumab and Doxorubicin in Participants With Advanced Soft Tissue Sarcoma (NCT02326025) | Eli Lilly and Company | 2015-01-22 |
| MG1 Maraba/MAGE-A3, With and Without Adenovirus Vaccine With Transgenic MAGE-A3 Insertion in Incurable MAGE-A3-Expressing Solid Tumours (NCT02285816) | Canadian Cancer Trials Group | 2015-01-22 |
| Safety, Pharmacokinetics, and Pharmacodynamics/Efficacy of SBC-103 in Mucopolysaccharidosis III, Type B (MPS IIIB) (NCT02324049) | Alexion Pharmaceuticals, Inc. | 2015-01-22 |
| Phase Ib Study of SAR650984 in Combination With Carfilzomib for Treatment of Relapsed or Refractory Multiple Myeloma (NCT02332850) | Thomas Martin, MD | 2015-01-21 |
| Nab-Paclitaxel Plus Gemcitabine With Concurrent MR-Guided IMRT in Patients With Locally Advanced Pancreatic Cancer (NCT02283372) | Washington University School of Medicine | 2015-01-21 |
| A Multicenter, Open Label, Phase I Dose Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Intravenous SAIT301 in Subjects With Advanced c-MET Positive (+) Solid Tumors Followed by Expansion in Selected Tumor Types (NCT02296879) | Young Suk Park | 2015-01-20 |
| MT2013-37R: Voriconazole Monitoring in Pediatric Stem Cell Transplant Patients (NCT02227797) | Masonic Cancer Center, University of Minnesota | 2015-01-19 |
| Safety and Tolerability Study of SHP626 in Overweight and Obese Adults (NCT02287779) | Mirum Pharmaceuticals, Inc. | 2015-01-19 |
| Safety, Preliminary Efficacy and Pharmacokinetics of ASN001 in Metastatic Castrate Resistant Prostate Cancer (NCT02349139) | Asana BioSciences | 2015-01-19 |
| Single Ascending Dose Challenge Study to Determine Safety and Reactogenicity of an Influenza Challenge Virus (NCT04106817) | WCCT Global | 2015-01-19 |
| A Study of Emactuzumab and Atezolizumab Administered in Combination in Participants With Advanced Solid Tumors (NCT02323191) | Hoffmann-La Roche | 2015-01-19 |
| A Study To Examine Safety, Pharmacokinetics, And Pharmacodynamic Of Pf 06412562 In Healthy Males (NCT02306876) | Pfizer | 2015-01-19 |
| Phase Ib Study AZD1775 in Combination With Carboplatin and Paclitaxel in Adult Asian Patients With Solid Tumours (NCT02341456) | AstraZeneca | 2015-01-16 |
| Safety and Efficacy Study of CC-122 Combined With Sorafenib for Primary Liver Cancer (NCT02323906) | Celgene | 2015-01-16 |
| CAVATAK (CVA21) in Non-muscle Invasive Bladder Cancer (VLA-012 CANON) (NCT02316171) | Viralytics | 2015-01-16 |
| GSK1278863 Effects on Eccentric Exercise-Induced Muscle Damage (NCT02231190) | GlaxoSmithKline | 2015-01-15 |
| Safety, Tolerability, and Pharmacokinetics of Multiple Rising Doses of BI 425809 Tablets for 12 Days to Young and Elderly Healthy Male and Female Volunteers and Comparison of Pharmacokinetics of a Single Oral Dose of BI 425809 (Morning Versus Evening) (NCT02337283) | Boehringer Ingelheim | 2015-01-15 |
| Study to Investigate Safety, Pharmacokinetic (PK), Pharmacodynamic (PD) and Clinical Activity of Trametinib in Subjects With Cancer or Plexiform Neurofibromas and Trametinib in Combination With Dabrafenib in Subjects With Cancers Harboring V600 Mutations (NCT02124772) | Novartis Pharmaceuticals | 2015-01-15 |
| Safety and Dose-escalation Study of AAV2-hCHM in Participants With CHM (Choroideremia) Gene Mutations (NCT02341807) | Spark Therapeutics, Inc. | 2015-01-15 |
| Vaccination of High Risk Breast Cancer Patients (NCT02229084) | University of Arkansas | 2015-01-14 |
| Interferon Gamma-1b Administered Topically for Macular Edema/Intraretinal Schisis Cysts in Rod-Cone Dystrophy (RCD) and Enhanced S-Cone Syndrome (ESCS) (NCT02338973) | National Eye Institute (NEI) | 2015-01-14 |
| A Study MLN2480 in Combination With MLN0128 or Alisertib, or Paclitaxel, or Cetuximab, or Irinotecan in Adult Participants With Advanced Nonhematologic Malignancies (NCT02327169) | Millennium Pharmaceuticals, Inc. | 2015-01-14 |
| To Investigate Pharmacokinetics (Absorption, Distribution, Elimination), Safety and Tolerability of a Single Oral Dose of 75 mg Molidustat Tablet in Male and Female Subjects Requiring Hemo- or Peritoneal Dialysis Compared to Healthy Subjects (NCT02312973) | Bayer | 2015-01-14 |
| Study of Safety and Efficacy of EGFR-TKI EGF816 in Combination With cMET Inhibitor INC280 in Adult Patients With EGFR Mutated Non Small Cell Lung Cancer. (NCT02335944) | Novartis Pharmaceuticals | 2015-01-13 |
| Phase I/II Study of SRP-4053 in DMD Patients (NCT02310906) | Sarepta Therapeutics, Inc. | 2015-01-13 |
| A Phase 1b/2a Randomized, Double-Blind, Placebo-controlled, Dose-escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MEDI8897, a Monoclonal Antibody With an Extended Half-life Against Respiratory Syncytial Virus, in Healthy Preterm Infants (NCT02290340) | MedImmune LLC | 2015-01-13 |
| A Trial In Healthy HIV-Negative Women To Assess The Effect Of Menses And Tampon Use On The Pharmacokinetics Of Dapivirine, Delivered By Dapivirine Vaginal Ring-004, Containing 25 Mg Of Dapivirine (NCT02858024) | International Partnership for Microbicides, Inc. | 2015-01-12 |
| Tacrobell tab_Phase1_PK (NCT02336854) | Chong Kun Dang Pharmaceutical | 2015-01-12 |
| Oral ONC201 in Treating Patients With Advanced Solid Tumors (NCT02250781) | Rutgers, The State University of New Jersey | 2015-01-12 |
| Safety Study of Nivolumab With Nab-Paclitaxel Plus or Minus Gemcitabine in Pancreatic Cancer, Nab-Paclitaxel / Carboplatin in Stage IIIB/IV Non-Small Cell Lung Cancer or Nab-Paclitaxel in Recurrent Metastatic Breast Cancer (NCT02309177) | Celgene | 2015-01-12 |
| Phase I Study of INO-1800 With or Without INO-9112 + EP in Chronic Hepatitis B Subjects (NCT02431312) | Inovio Pharmaceuticals | 2015-01-12 |
| Clinical Trial to Evaluate Safety, Tolerability and Pharmacokinetics and Anti-tumor Activity of HM95573 (NCT02405065) | Hanmi Pharmaceutical Company Limited | 2015-01-12 |
| Safety and Immunogenicity of a 10 Valent Pneumococcal Conjugate Vaccine (SIILPCV10) in Healthy Adults, Toddlers, Infants (NCT02308540) | PATH | 2015-01-12 |
| A Study Evaluating Safety and Pharmacokinetics of ABBV-221 in Subjects With Advanced Solid Tumor Types Likely to Exhibit Elevated Levels of Epidermal Growth Factor Receptor (NCT02365662) | AbbVie | 2015-01-09 |
| Study to Investigate the Safety and Tolerability of Odronextamab in Patients With CD20+ B-Cell Malignancies (NCT02290951) | Regeneron Pharmaceuticals | 2015-01-09 |
| Controlled Level EVERolimus in Acute Coronary Syndromes (NCT01529554) | University of Zurich | 2015-01-08 |
| Ceritinib and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors or Locally Advanced or Metastatic Pancreatic Cancer (NCT02227940) | Roswell Park Cancer Institute | 2015-01-08 |
| RADVAX: A Stratified Phase I Trial of Pembrolizumab With Hypofractionated Radiotherapy in Patients With Advanced and Metastatic Cancers (NCT02303990) | Abramson Cancer Center at Penn Medicine | 2015-01-08 |
| Clinical Study on Macitentan, RT and TMZ Concurrent Therapy Followed by Maintenance Macitentan and TMZ in Newly Diagnosed Glioblastoma (NCT02254954) | Actelion | 2015-01-08 |
| A Safety and Immunogenicity Study of Heterologous and Homologous Prime-Boost Ebola Vaccine Regimens in Healthy Participants (NCT02325050) | Janssen Vaccines & Prevention B.V. | 2015-01-08 |
| To Evaluate Effects of GSK2256294 on Pulmonary Artery Pressure in Healthy Volunteers Under Normoxic and Hypoxic Conditions (NCT02262689) | GlaxoSmithKline | 2015-01-08 |
| Phase 1 Study of SGI-110 in Patients With Acute Myeloid Leukemia (NCT02293993) | Otsuka Pharmaceutical Co., Ltd. | 2015-01-07 |