| GSK961081 Alone and With Fluticasone Furoate (FF), Phase 1 (Ph1), Single Dose Regimen (SD), Repeat Dose Regimen (RD), Pharmacokinetic (PK) Study in Healthy Volunteer (HV) (NCT02666287) | GlaxoSmithKline | 2016-01-27 |
| Safety and Efficacy Study of Pembrolizumab (MK-3475) in Combination With Chemotherapy as Neoadjuvant Treatment for Participants With Triple Negative Breast Cancer (TNBC) (MK-3475-173/KEYNOTE-173) (NCT02622074) | Merck Sharp & Dohme LLC | 2016-01-27 |
| Pentoxifylline PKB171 Gel in Healthy Females Volunteers (NCT07017114) | Prokrea BCN, S.L. | 2016-01-27 |
| Dose Escalation Study of Preoperative SBRT for High Risk Prostate Cancer (NCT02572284) | H. Lee Moffitt Cancer Center and Research Institute | 2016-01-27 |
| Study to Evaluate Safety and Pharmacokinetics of GS-4059 (Tirabrutinib) in Healthy Volunteers and Participants With Rheumatoid Arthritis (RA) (NCT02626026) | Gilead Sciences | 2016-01-26 |
| Trial Of Hypofractionated Radiotherapy In Combination With MEDI4736 And Tremelimumab For Patients With Metastatic Melanoma And Lung, Breast And Pancreatic Cancers (NCT02639026) | Abramson Cancer Center at Penn Medicine | 2016-01-26 |
| A Study Evaluating the Pharmacokinetics of Doravirine (MK-1439) in Participants With Severe Renal Impairment (MK-1439-051) (NCT02641067) | Merck Sharp & Dohme LLC | 2016-01-26 |
| Study to Assess Safety, Tolerability and Pharmacokinetics of Treamid in Healthy Volunteers (NCT04428593) | PHARMENTERPRISES LLC | 2016-01-25 |
| Clozapine-induced Hypersalivation - Feasibility Trial (NCT02613494) | Mersey Care NHS Trust | 2016-01-25 |
| Study Evaluating the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Therapeutic Activity of Selicrelumab (RO7009789) With Vanucizumab or Bevacizumab in Participants With Metastatic Solid Tumors (NCT02665416) | Hoffmann-La Roche | 2016-01-25 |
| A Study to Evaluate the Efficacy and Safety of Vismodegib in Combination With Ruxolitinib for the Treatment of Intermediate- or High-Risk Myelofibrosis (MF) (NCT02593760) | Hoffmann-La Roche | 2016-01-25 |
| Phase I Study of Enadenotucirev and PD-1 Inhibitor in Subjects With Metastatic or Advanced Epithelial Tumors (NCT02636036) | Akamis Bio | 2016-01-25 |
| Safety, Tolerability and Pharmacokinetics and Effect on Inflammation of Oral BI 1026706 in Patients With COPD (NCT02642614) | Boehringer Ingelheim | 2016-01-25 |
| A Phase 1b/2, Multicenter, Open-label Study of ACP-196 in Subjects With Recurrent Glioblastoma Multiforme (GBM) (NCT02586857) | Acerta Pharma BV | 2016-01-25 |
| Pembrolizumab Combined With Itacitinib (INCB039110) and/or Pembrolizumab Combined With INCB050465 in Advanced Solid Tumors (NCT02646748) | Incyte Corporation | 2016-01-25 |
| A Phase I Study to Assess PK of AZD7986 Alone & With Verapamil, Itraconazole or Diltiazem in Healthy Subjects (NCT02653872) | AstraZeneca | 2016-01-22 |
| Effect of Adjunctive Systemic Vitamin E on Clinical Parameters and Salivary Total Antioxidant Capacity in Symptomatic Oral Lichen Planus Patients: Randomized-controlled Clinical Trial (NCT04126720) | Cairo University | 2016-01-22 |
| A Study of the Pharmacokinetics of Uprifosbuvir (MK-3682) and Ruzasvir (MK-8408) in Participants With Moderate and Severe Hepatic Insufficiency (MK-3682-029) (NCT02666352) | Merck Sharp & Dohme LLC | 2016-01-22 |
| A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of CHF6297 in Healthy Subjects and Patients With COPD (NCT02815488) | Chiesi Farmaceutici S.p.A. | 2016-01-22 |
| T Cells Expressing a Fully-human AntiCD19 Chimeric Antigen Receptor for Treating B-cell Malignancies (NCT02659943) | National Cancer Institute (NCI) | 2016-01-21 |
| Fusion Protein rHSA/GCSFclinical Study on Breast Cancer Patients (NCT03246009) | Tianjin SinoBiotech Ltd. | 2016-01-21 |
| Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GS-9674 (Cilofexor), and the Effect of Food on GS-9674 Pharmacokinetics and Pharmacodynamics (NCT02654002) | Gilead Sciences | 2016-01-20 |
| CT Perfusion Imaging in Predicting Treatment Response in Patients With Non-small Cell Lung Cancer or Lung Metastases Treated With Stereotactic Ablative Radiation Therapy (NCT02693080) | Stanford University | 2016-01-19 |
| Local Ablative Strategies After Endovascular Radioembolization (NCT02611661) | Washington University School of Medicine | 2016-01-19 |
| Pharmacokinetics of MK-3682B in Participants With Moderate to Severe Renal Insufficiency (MK-3682B-030) (NCT02661126) | Merck Sharp & Dohme LLC | 2016-01-19 |
| Study of 5-fluorouracil (5-FU), Nab®1-paclitaxel, Bevacizumab, Leucovorin, and Oxaliplatin in Patients With Metastatic Pancreatic Cancer (NCT02620800) | Celgene | 2016-01-18 |
| Phase I Study of LXH254 in Patients With Advanced Solid Tumors Haboring MAPK Pathway Alterations (NCT02607813) | Novartis Pharmaceuticals | 2016-01-18 |
| Onalespib and Paclitaxel in Treating Patients With Advanced Triple Negative Breast Cancer (NCT02474173) | National Cancer Institute (NCI) | 2016-01-15 |
| An Assessment of Pharmacokinetic Gemigliptin and Metformin Interactions in Healthy Mexican Volunteers (NCT03310749) | Stendhal Americas, S.A. | 2016-01-15 |
| A Study of Oral Vismodegib in Combination With Pirfenidone in Participants With Idiopathic Pulmonary Fibrosis (NCT02648048) | Hoffmann-La Roche | 2016-01-15 |
| Anti-CD19 Chimeric Antigen Receptor (CAR)-Transduced T Cell Therapy for Patients With B Cell Malignancies (NCT03076437) | Shenzhen Institute for Innovation and Translational Medicine | 2016-01-15 |
| Assessment of Tolerance of Mobilizing Peripheral Hematopoietic Stem Cells by Plerixafor in Sickle Cell Patients (NCT02212535) | Assistance Publique - Hôpitaux de Paris | 2016-01-15 |
| Acute Exercise Cardioprotection From Doxorubicin (NCT02006979) | University of British Columbia | 2016-01-15 |
| Stromal TARgeting for PAncreatic Cancer (STAR_PAC) (NCT03307148) | Barts & The London NHS Trust | 2016-01-15 |
| Investigation of Pharmacokinetic Drug-drug Interaction of BI 409306 and Donepezil in Healthy Male and Female Subjects (NCT02635750) | Boehringer Ingelheim | 2016-01-15 |
| Single Dosing Clinical Trial of HL151 (NCT02682745) | Hanlim Pharm. Co., Ltd. | 2016-01-15 |
| Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery (NCT02336087) | City of Hope Medical Center | 2016-01-14 |
| Quinacrine-Capecitabine Combinatorial Therapy for Advanced Stage Colorectal Adenocarcinoma (NCT01844076) | Fox Chase Cancer Center | 2016-01-14 |
| Phase I Pilot Study of Biodistribution, Metabolism and Excretion of Novel Radiotracer [18F]Fluorthanatrace (FTT) by PET/CT (NCT02637934) | Abramson Cancer Center at Penn Medicine | 2016-01-14 |
| A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant Medications (NCT06004947) | Amgen | 2016-01-14 |
| Hodgkin Lymphoma Treatment With Adcetris and Levact in the Old Patient (NCT02467946) | Centre Antoine Lacassagne | 2016-01-14 |
| BGB 3111 in Combination With Obinutuzumab in Participants With B-Cell Lymphoid Malignancies (NCT02569476) | BeiGene | 2016-01-13 |
| Personalized Kinase Inhibitor Therapy Combined With Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia (NCT02779283) | OHSU Knight Cancer Institute | 2016-01-13 |
| CD22 Redirected Autologous T Cells for ALL (NCT02650414) | University of Pennsylvania | 2016-01-13 |
| Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcoma (NCT02659930) | National Cancer Institute (NCI) | 2016-01-13 |
| Drug Challenges Without Prior Skin Testing (NCT03158831) | Montefiore Medical Center | 2016-01-13 |
| A Study to Evaluate the Safety, Tolerability and Microbiome Dynamics of SER-287 in Subjects With Mild-to-Moderate Ulcerative Colitis (NCT02618187) | Seres Therapeutics, Inc. | 2016-01-13 |
| A Study Comparing Once-Daily vs. Twice-Daily Dosing of X4P-001 in Healthy Volunteers (NCT02680782) | X4 Pharmaceuticals | 2016-01-12 |
| A Study of U-500 Insulin (LY041001) in Participants With Type 2 Diabetes (NCT02588950) | Eli Lilly and Company | 2016-01-12 |
| A Study to Assess the Bioavailability and to Compare the Pharmacokinetics of AZD7594 Inhaled Via Monodose Inhaler and Multiple-dose Dry Powder Inhalers (DPI) or Pressurized Metered-dose Inhaler (pMDI) in Healthy Male Subjects (NCT02648438) | AstraZeneca | 2016-01-12 |
| A Study to Assess the Drug-drug Interaction of BMS 663068 With Methadone and Also With Buprenorphine/Naloxone (NCT02666001) | ViiV Healthcare | 2016-01-12 |
| Pacritinib and Chemotherapy in Treating Patients With Acute Myeloid Leukemia and FLT3 Mutations (NCT02323607) | Bhavana Bhatnagar | 2016-01-12 |
| A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD7594 Inhaled Formulation in Healthy Japanese Men (NCT02645253) | AstraZeneca | 2016-01-12 |
| Vascepa to Accelerate Lipoprotein Uptake and Elimination (NCT03885661) | University of Pennsylvania | 2016-01-11 |
| A Study to Determine Dose and Regimen of Durvalumab as Monotherapy or in Combination With Pomalidomide With or Without Dexamethasone in Subjects With Relapsed and Refractory Multiple Myeloma (NCT02616640) | Celgene | 2016-01-11 |
| A Study to Learn How Safe and Tolerable Odronextamab and Cemiplimab Are in Adult Patients With B-cell Malignancies (NCT02651662) | Regeneron Pharmaceuticals | 2016-01-11 |
| Bone Marrow Derived Mesenchymal Stem Cells in Improving Heart Function in Patients With Heart Failure Caused by Anthracyclines (NCT02408432) | M.D. Anderson Cancer Center | 2016-01-11 |
| EDP-494-001: A Study of EDP-494 in Healthy Subjects and Hepatitis C Patients (NCT02652377) | Enanta Pharmaceuticals, Inc | 2016-01-10 |
| CC-11050 in Human Immunodeficiency Virus-1-Infected Adults With Suppressed Plasma Viremia on Antiretroviral Therapy (APHRODITE) (NCT02652546) | National Institute of Allergy and Infectious Diseases (NIAID) | 2016-01-09 |
| ALT-803 Plus Nivolumab in Patients With Pretreated, Advanced or Metastatic Non-Small Cell Lung Cancer (NCT02523469) | Medical University of South Carolina | 2016-01-08 |
| [11C]MK-6884 Positron Emission Tomography (PET) Tracer Validation Trial (MK-6884-001) (NCT02621606) | Merck Sharp & Dohme LLC | 2016-01-08 |
| Study of Tremelimumab Alone or Combined With Olaparib for Patients With Persistent EOC (Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Carcinoma) (NCT02485990) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2016-01-08 |
| Genetic Variability in CYP2D6 in U.S Active Duty Population (NCT02960568) | Walter Reed Army Institute of Research (WRAIR) | 2016-01-08 |
| A Study to Evaluate the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics of TAK-117 (MLN1117) in Healthy Participants (NCT02625259) | Millennium Pharmaceuticals, Inc. | 2016-01-08 |
| Pharmacokinetics and Adhesion of Lidocaine Topical System 1.8% Under Conditions of Heat and Exercise (NCT04150536) | Scilex Pharmaceuticals, Inc. | 2016-01-08 |
| A Study of the Safety, Pharmacokinetics, and Therapeutic Activity of RO6958688 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Carcinoembryonic Antigen (CEA)-Positive Solid Tumors (NCT02650713) | Hoffmann-La Roche | 2016-01-07 |
| A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Risdiplam (RO7034067) Given by Mouth in Healthy Volunteers (NCT02633709) | Hoffmann-La Roche | 2016-01-07 |
| Dose Dependent Effects of tDCS on Post-Operative Pain (NCT02241967) | VA Office of Research and Development | 2016-01-07 |
| A Study of Safety, Tolerability and Pharmacokinetics of Nivolumab in Chinese Subjects With Previously Treated Advanced or Recurrent Solid Tumors (NCT02593786) | Bristol-Myers Squibb | 2016-01-07 |
| EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma (NCT02601937) | Epizyme, Inc. | 2016-01-07 |
| Investigation of Nicotine Seeking Behavior in Current Smokers (NCT03670212) | Wayne State University | 2016-01-07 |
| Lentiviral-mediated Gene Therapy of Fanconi Anemia Patients Subtype A (NCT03157804) | Hospital Infantil Universitario Niño Jesús, Madrid, Spain | 2016-01-07 |
| Study Evaluating the Safety and Pharmacokinetics of JCAR017 in B-cell Non-Hodgkin Lymphoma (TRANSCEND-NHL-001) (NCT02631044) | Juno Therapeutics, a Subsidiary of Celgene | 2016-01-06 |
| Study to Investigate the Effect of Formulation and Food on the Pharmacokinetics of GDC-0810 (NCT02722018) | Genentech, Inc. | 2016-01-06 |
| Intermittent High-Dose Lapatinib in Tandem With Capecitabine for HER2 Overexpressed/Amplified Metastatic Breast Cancer With Central Nervous System (CNS) Metastases (NCT02650752) | Memorial Sloan Kettering Cancer Center | 2016-01-06 |
| Taste Properties of HIV Inhibitor (NCT02608918) | ViiV Healthcare | 2016-01-05 |
| Humanized Anti-GD2 Antibody Hu3F8 and Allogeneic Natural Killer Cells for High-Risk Neuroblastoma (NCT02650648) | Memorial Sloan Kettering Cancer Center | 2016-01-05 |
| Study to Evaluate Bioavailability of Apremilast Oral Suspension Relative to Tablet and to Assess Effect of Food on the Pharmacokinetics (PK) of the Oral Suspension (NCT02641353) | Amgen | 2016-01-05 |
| Dose Finding Study of BI 836880 in Patients With Solid Tumors (NCT02674152) | Boehringer Ingelheim | 2016-01-05 |
| Study of MK-3475 Alone or in Combination With Copanlisib in Relapsed or Refractory NK and T-cell Non-Hodgkin Lymphoma (NCT02535247) | Fox Chase Cancer Center | 2016-01-05 |
| Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin (NCT02266329) | VA Office of Research and Development | 2016-01-04 |
| Clinical Trial to Compare the Pharmacokinetics of TAH Tablet in Comparison to the Co-administration of Telmisartan, Amlodipine and Hydrochlorothiazide in Healthy Male Volunteers (NCT02739672) | IlDong Pharmaceutical Co Ltd | 2016-01-02 |
| A PK and Safety Evaluation of HORIZANT (Gabapentin Enacarbil) in Adolescents With Moderate-to-Severe Primary RLS (NCT02633657) | XenoPort, Inc. | 2016-01-01 |
| Buccal Fat Pad Derived Stem Cells With Cortical Tenting in Posterior Mandible Reconstruction (NCT02745366) | Shahid Beheshti University of Medical Sciences | 2016-01-01 |
| Assessment of the Changes in Cortical and Medullary Renal Blood Flow During Exercise in Healthy Subjects Using Contrast Enhanced Ultrasound (NCT02672722) | University of Virginia | 2016-01-01 |
| A Drug-drug Interaction Study of DP-R213 (NCT02654093) | Alvogen Korea | 2016-01-01 |
| A Pilot Study of FFP104 in Subjects With Crohn's Disease (NCT02465944) | Fast Forward Pharmaceuticals | 2016-01-01 |
| Contrast Ultrasound Detection of Sentinel Lymph Nodes (NCT02652923) | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 2016-01-01 |
| Buparlisib and Ofatumumab or Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia (NCT02614508) | Emory University | 2016-01-01 |
| Changes in Adiponectin and Cardiovascular Disease Risk Factors in Overweight Patients (NCT02882672) | University of Isfahan | 2016-01-01 |
| Study to Evaluate The Effect Of Sertraline on the Cardiac Repolarization in Healthy Subjects (NCT02651623) | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 2016-01-01 |
| An Exploratory Study Investigating Safety, Tolerability and Pharmacokinetics of Ascending Doses of Lu AE04621 in Parkinson Disease Patients (NCT02649608) | H. Lundbeck A/S | 2016-01-01 |
| Phase I Study of Combination of Gedatolisib With Palbociclib and Faslodex in Patients With ER+/HER2- Breast Cancer (NCT02626507) | Hoffman Oncology | 2016-01-01 |
| ASIS for Botox in Cervical Dystonia (NCT02074293) | li nguyen | 2016-01-01 |
| Pharmacokinetic Interaction and the Safety of Inhaled CHF5259 and CHF6001 (NCT03004495) | Chiesi Farmaceutici S.p.A. | 2016-01-01 |
| Phase 1 Study of PBTZ169 (NCT03036163) | Nearmedic Plus LLC | 2016-01-01 |
| 3,3'-Diindolylmethane in Patients With Systemic Lupus Erythematosus (NCT02483624) | Northwell Health | 2016-01-01 |
| IRDye800CW-BBN PET-NIRF Imaging Guiding Surgery in Patients With Lower Grade Glioma (NCT03407781) | Deling Li | 2016-01-01 |
| A Drug-drug Interaction Study Between Daclatasvir and Metformin (NCT02565862) | Radboud University Medical Center | 2016-01-01 |
| Pancreatic Core Biopsy Needle Study in Patients Suspected of Pancreatic Malignancy (NCT03016637) | Odense University Hospital | 2016-01-01 |