| A Study of RC48-ADC in Subjects With Advanced Breast Cancer (NCT03052634) | RemeGen Co., Ltd. | 2016-12-23 |
| A Clinical Trial to Evaluate the Pharmacokinetics and Safety/Tolerability of Fimasartan and Atorvastatin in Healthy Male Volunteers. (NCT02994745) | Boryung Pharmaceutical Co., Ltd | 2016-12-23 |
| Study of Veliparib in Combination With Nivolumab and Platinum Doublet Chemotherapy in Participants With Metastatic or Advanced Non-Small Cell Lung Cancer (NSCLC) (NCT02944396) | AbbVie | 2016-12-23 |
| A Study of Pharmacokinetic Comparison of Two Recombinant Exendin-4 Formulations in Chinese Healthy Male Subjects (NCT03199261) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2016-12-23 |
| A Study of Daratumumab in Combination With Atezolizumab Compared With Atezolizumab Alone in Participants With Previously Treated Advanced or Metastatic Non-Small Cell Lung Cancer (NCT03023423) | Janssen Research & Development, LLC | 2016-12-23 |
| Bioequivalence Study of Amlodipine and Norvasc Under Fasting and FED Conditions in Chinese Healthy Volunteers (NCT02974439) | Shanghai Haini Pharmaceutical Co., Ltd. | 2016-12-23 |
| CIMAvax Vaccine, Nivolumab, and Pembrolizumab in Treating Patients With Advanced Non-small Cell Lung Cancer or Squamous Head and Neck Cancer (NCT02955290) | Roswell Park Cancer Institute | 2016-12-22 |
| A Study of Ixekizumab in Participants With Plaque Psoriasis (NCT02993471) | Eli Lilly and Company | 2016-12-22 |
| mTORC1/mTORC2 Kinase Inhibitor AZD2014 in Previously Treated Glioblastoma Multiforme (NCT02619864) | Canadian Cancer Trials Group | 2016-12-22 |
| ODM-207 in Patients With Advance Solid Tumours (NCT03035591) | Orion Corporation, Orion Pharma | 2016-12-22 |
| Treatment of Advanced Solid Tumors With TSA-CTL(Tumor Specific Antigen-Induced Cytotoxic T Lymphocytes) (NCT02959905) | BGI, China | 2016-12-22 |
| Food-Effect and Metabolism Study in Healthy Subjects (NCT03062982) | Jiangsu HengRui Medicine Co., Ltd. | 2016-12-21 |
| Study of the Efficacy, Safety and Pharmacokinetics of Pamiparib (BGB-290) in Participants With Advanced Solid Tumors (NCT03333915) | BeiGene | 2016-12-21 |
| Safety, Tolerability, and Immunogenicity of mRNA-1325 in Healthy Adult Subjects (NCT03014089) | ModernaTX, Inc. | 2016-12-21 |
| Intravesical Photodynamic Therapy (PDT) in BCG Refractory High-Risk Non-muscle Invasive Bladder Cancer (NMIBC) Patients (NCT03053635) | Theralase® Technologies Inc. | 2016-12-21 |
| A Phase II Study of Atezolizumab in Combination With Cisplatin + Gemcitabine Before Surgery to Remove the Bladder Cancer (NCT02989584) | Memorial Sloan Kettering Cancer Center | 2016-12-20 |
| A Study to Investigate the Effect of Renal Function and Hemodialysis on the Pharmacokinetics (PK) of RO7079901 (NCT02975388) | Hoffmann-La Roche | 2016-12-20 |
| Bioequivalence of a Fixed Dose Combination Tablet Containing 400 mg Ibuprofen and 60 mg Pseudoephedrine-HCl Compared to Two Film Coated Fixed Dose Combination Tablets RhinAdvil(R)(200 mg Ibuprofen and 30 mg Pseudoephedrine-HCl) Administered in Healthy Subjects (NCT02963701) | Boehringer Ingelheim | 2016-12-20 |
| An Open-Label Phase 1/2 Study of Itacitinib in Combination With Osimertinib in Subjects With Non-Small Cell Lung Cancer (NCT02917993) | Incyte Corporation | 2016-12-20 |
| Neoadjuvant MEDI 4736 +/- Tremelimumab in Locally Advanced Renal Cell Carcinoma (NCT02762006) | Moshe Ornstein | 2016-12-20 |
| A Dose Finding and Expansion Study of RO7051790 Administered Orally in Participants With Relapsed, Extensive-Stage Disease Small Cell Lung Cancer (ED SCLC) (NCT02913443) | Hoffmann-La Roche | 2016-12-20 |
| A Study to Determine Safety, Feasibility and Efficacy of JCAR015 in Adult Subjects With B-Cell Acute Lymphoblastic Leukemia (NCT02973191) | Celgene | 2016-12-20 |
| A Study to Estimate the Effect of AZD5718 on the Pharmacokinetics (What Does the Body Does to the Drug) of Rosuvastatin to Measure the Relative Bioavailability (the Extent to Which a Drug or Other Substance Becomes Available to the Body) of AZD5718 Oral Suspension vs AZD5718 Immediate Release Tablet (NCT02963116) | AstraZeneca | 2016-12-20 |
| Pharmacokinetics of Dabrafenib in Subjects With Hepatic Impairment (NCT02873650) | Novartis Pharmaceuticals | 2016-12-20 |
| Study of ProTmune for Allogeneic HCT in Adult Patients With Hematologic Malignancies (NCT02743351) | Fate Therapeutics | 2016-12-20 |
| A Study of LY3209590 in Healthy Participants and Participants With Type 2 Diabetes (NCT02942914) | Eli Lilly and Company | 2016-12-20 |
| Spesolimab (BI 655130) Single Dose in Generalized Pustular Psoriasis (NCT02978690) | Boehringer Ingelheim | 2016-12-19 |
| Study of Avelumab With or Without Entinostat in Participants With Advanced Epithelial Ovarian Cancer (NCT02915523) | Syndax Pharmaceuticals | 2016-12-19 |
| Pharmacokinetics of Dabrafenib in Subjects With Renal Impairment (NCT02852239) | Novartis Pharmaceuticals | 2016-12-19 |
| Accelerated Radiation Therapy (ART) to the Breast and Nodal Stations (NCT02917421) | Weill Medical College of Cornell University | 2016-12-19 |
| TSEB and Brentuximab for Treatment of Mycosis Fungoides & Sezary Syndrome (NCT02822586) | Virginia Commonwealth University | 2016-12-19 |
| A Dose Escalation and Cohort Expansion Study of NKTR-214 in Combination With Nivolumab and Other Anti-Cancer Therapies in Patients With Select Advanced Solid Tumors (NCT02983045) | Nektar Therapeutics | 2016-12-19 |
| Subcutaneous Furosemide in Acute Decompensated Heart Failure Pilot (NCT02877095) | Adrian Hernandez | 2016-12-19 |
| Compare Daily Ulipristal Acetate and Combined Oral Contraceptive Effects on Breast Epithelial Cell Proliferation (NCT02922127) | Columbia University | 2016-12-16 |
| Assessment of the Safety, Tolerability and Pharmacodynamics After Administration of One Dose of AZD8601 to Male Patients With Type II Diabetes Mellitus (T2DM) (NCT02935712) | AstraZeneca | 2016-12-16 |
| Pembrolizumab and Decitabine for Refractory or Relapsed Acute Myeloid Leukemia (NCT02996474) | National Heart, Lung, and Blood Institute (NHLBI) | 2016-12-16 |
| Nivolumab and Radiation Therapy With or Without Ipilimumab in Treating Patients With Brain Metastases From Non-small Cell Lung Cancer (NCT02696993) | M.D. Anderson Cancer Center | 2016-12-16 |
| Clinical Trial of Oral Ciprofloxacin and Etoposide in Subjects With Resistant Acute Myeloid Leukemia (AML)(UF-AML-CE-101) (NCT02773732) | University of Florida | 2016-12-16 |
| Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID (NCT02999984) | University of California, Los Angeles | 2016-12-16 |
| Targeting Pro-Inflammatory Cells in Idiopathic Pulmonary Fibrosis: a Human Trial (NCT02874989) | Wake Forest University Health Sciences | 2016-12-16 |
| Evaluating of Pharmacokinetic Profile of BCWP_C003 and Co-administration of Rosuvastatin and Metformin (NCT01992211) | BC World Pharm Co. Ltd. | 2016-12-15 |
| Precise Local Injection of Anti-cancer Drugs Using Presage's CIVO Device in Soft Tissue Sarcoma (NCT03056599) | Presage Biosciences | 2016-12-15 |
| Hyperpolarized Carbon-13 Imaging of Metastatic Prostate Cancer (NCT02844647) | Sunnybrook Health Sciences Centre | 2016-12-15 |
| First-in-human Study of Oral TP-0903 (a Novel Inhibitor of AXL Kinase) in Patients With Advanced Solid Tumors (NCT02729298) | Sumitomo Pharma America, Inc. | 2016-12-14 |
| A Study of Budigalimab (ABBV-181) in Participants With Advanced Solid Tumors (NCT03000257) | AbbVie | 2016-12-14 |
| Bioequivalence Study (Candesartan 16 mg and Amlodipine 10 mg) (NCT02988362) | HanAll BioPharma Co., Ltd. | 2016-12-14 |
| A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of RO7049389 in Healthy Volunteers and Chronic Hepatitis B Virus (HBV) Infected Participants (NCT02952924) | Hoffmann-La Roche | 2016-12-14 |
| A Dose Escalation Study to Assess PK, Safety and Tolerability of INC280 When Taken With Food in cMET Dysregulated Advanced Solid Tumors. (NCT02925104) | Novartis Pharmaceuticals | 2016-12-14 |
| Ph 1B B-701 in Combination With Pembrolizumab in Metastatic Transitional Cell Carcinoma of the Urothelial Tract (NCT02925533) | Mark Pomerantz, MD | 2016-12-14 |
| Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma (NCT02942264) | National Cancer Institute (NCI) | 2016-12-14 |
| ABC294640 (Opaganib) in Refractory / Relapsed Multiple Myeloma (NCT02757326) | RedHill Biopharma Limited | 2016-12-13 |
| Phase 1 Study of Tremelimumab, Durvalumab, High-dose Chemotherapy, + Autologous Stem Cell Transplant (NCT02716805) | Ludwig Institute for Cancer Research | 2016-12-13 |
| A Study to Assess the Pharmacokinetics and Safety of Recombinant Human Murine Chimeric Anti CD20 Monoclonal Antibody Injection (IBI301) Compared to Rituximab Injection in CD20 Positive B Cell Lymphoma Patients (NCT02945215) | Innovent Biologics (Suzhou) Co. Ltd. | 2016-12-13 |
| To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer (NCT03006172) | Genentech, Inc. | 2016-12-13 |
| Varlitinib in Combination With Gemcitabine and Cisplatin for Treatment naïve Advanced or Metastatic BTC (NCT02992340) | ASLAN Pharmaceuticals | 2016-12-13 |
| Effect of Number of Remote Limb Ischemic Conditioning Cycles on Learning Enhancement (NCT03512041) | Washington University School of Medicine | 2016-12-13 |
| Study of Vibostolimab Alone and in Combination With Pembrolizumab in Advanced Solid Tumors (MK-7684-001) ( KEYVIBE-001) (NCT02964013) | Merck Sharp & Dohme LLC | 2016-12-13 |
| A Study to Evaluate Safety, Tolerability and Immune Response in Adults Allergic to Peanut After Receiving Intradermal or Intramuscular Administration of ASP0892 (ARA-LAMP-vax), a Single Multivalent Peanut (Ara h1, h2, h3) Lysosomal Associated Membrane Protein DNA Plasmid Vaccine (NCT02851277) | Astellas Pharma Global Development, Inc. | 2016-12-13 |
| VRC 320: A Phase I, Randomized Clinical Trial to Evaluate the Safety and Immunogenicity of a Zika Virus DNA Vaccine, VRC-ZKADNA090-00-VP, Administered Via Needle and Syringe or Needle-free Injector, PharmaJet, inHealthy Adults (NCT02996461) | National Institute of Allergy and Infectious Diseases (NIAID) | 2016-12-12 |
| A Study of LY3323795 in Healthy Participants (NCT02989389) | Eli Lilly and Company | 2016-12-12 |
| A Phase 1 Study of Roxadustat in Subjects With Different Degrees of Renal Function (NCT02965040) | Astellas Pharma Europe B.V. | 2016-12-12 |
| A Study in Healthy Volunteers and in Participants With Chronic Hepatitis B to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of RO7020531 (NCT02956850) | Hoffmann-La Roche | 2016-12-12 |
| Study of Molecular-targeted Therapy Using Zinc Finger Nuclease in Cervical Precancerous Lesions (NCT02800369) | Huazhong University of Science and Technology | 2016-12-10 |
| Study to Assess the Safety, Tolerability and Pharmacokinetics and Pharmacodynamics of AZD0284 in Healthy Subjects (NCT02976831) | AstraZeneca | 2016-12-09 |
| Safety and Tolerability of Zelquistinel in Normal Human Volunteers (NCT04981561) | Syndeio Biosciences, Inc | 2016-12-09 |
| A Study of PTX-200 (Triciribine) Plus Cytarabine in Refractory or Relapsed Acute Leukemia (NCT02930109) | Prescient Therapeutics, Ltd. | 2016-12-09 |
| A Study of Gemcitabine/Nab-paclitaxel and Radiation Therapy Followed by Surgery in Patients With Advanced Pancreatic Cancer (NCT02481635) | University Health Network, Toronto | 2016-12-08 |
| PEN-221 in Somatostatin Receptor 2 Expressing Advanced Cancers Including Neuroendocrine and Small Cell Lung Cancers (NCT02936323) | Tarveda Therapeutics | 2016-12-08 |
| Safety and Tolerability of Topically Applied Bovine Lung Surfactant on Intact Skin (NCT02985437) | Prof. Dr. Dr. Ursula Mirastschijski | 2016-12-08 |
| Ph1b Study of Oraxol in Comb. w. Ramucirumab in Patients w. Gastric, Gastro-esophageal, or Esophageal Cancers (NCT02970539) | Athenex, Inc. | 2016-12-08 |
| Study of Safety, Tolerability, and Pharmacokinetics of REGN2477 Alone and in Combination With REGN1033 in Healthy Postmenopausal Women and Healthy Adult Men (NCT02943239) | Regeneron Pharmaceuticals | 2016-12-08 |
| Zika Virus Purified Inactivated Vaccine (ZPIV) Accelerated Vaccination Schedule Study (NCT02937233) | Kathryn Stephenson | 2016-12-08 |
| Study of IRX4204 With Erlotinib in Previously Treated Advanced NSCLC (NCT02991651) | Io Therapeutics | 2016-12-07 |
| Evaluating the Safety and Immunogenicity of HIV Clade C DNA Vaccine and MF59- or AS01B-Adjuvanted Clade C Env Protein Vaccines in Various Combinations in Healthy, HIV-Uninfected Adults (NCT02915016) | National Institute of Allergy and Infectious Diseases (NIAID) | 2016-12-07 |
| A Trial of Belzutifan (PT2977, MK-6482) Tablets In Patients With Advanced Solid Tumors (MK-6482-001) (NCT02974738) | Peloton Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 2016-12-07 |
| A Study to Compare Pharmacokinetics (PK) of Etrolizumab Administered Subcutaneously by a Prefilled Syringe With Needle Safety Device (PFS-NSD) or an Auto-injector (AI) (NCT02996019) | Genentech, Inc. | 2016-12-07 |
| Addition of X4P-001 to Nivolumab Treatment in Participants With Renal Cell Carcinoma (NCT02923531) | X4 Pharmaceuticals | 2016-12-07 |
| Safety and Pharmacokinetics of Abicipar Pegol Intravitreal Injections in Patients With Neovascular AMD (NCT02859766) | Allergan | 2016-12-07 |
| Pilot BA Study of New LY03005 vs Pristiq (NCT02988024) | Luye Pharma Group Ltd. | 2016-12-07 |
| A Study of Nivolumab Safety and Pharmacokinetics in Patients With Severe Sepsis or Septic Shock. (NCT02960854) | Bristol-Myers Squibb | 2016-12-07 |
| Peptide Targets for Glioblastoma Against Novel Cytomegalovirus Antigens (NCT02864368) | Eric Thompson, M.D. | 2016-12-07 |
| To Assess and Compare the Efficacy of Cyclosporine Versus Azathioprine in the Treatment of Chronic Refractory Urticaria (NCT03250143) | Post Graduate Institute of Medical Education and Research, Chandigarh | 2016-12-06 |
| A Single-Dose Positron Emission Tomography (PET) Study to Determine the Effect of TAK-041 on Amphetamine-Induced Dopamine Release in the Central Nervous System (CNS) (NCT02959892) | Neurocrine Biosciences | 2016-12-05 |
| Aclarubicin for the Treatment of Retinal Vasculopathy With Cerebral Leukodystrophy (NCT02723448) | Washington University School of Medicine | 2016-12-05 |
| Psilocybin for the Treatment of Cluster Headache (NCT02981173) | Yale University | 2016-12-05 |
| Safety and Efficacy of Allogeneic MSCs in Promoting T-regulatory Cells in Patients With Small Abdominal Aortic Aneurysms (NCT02846883) | VA Office of Research and Development | 2016-12-05 |
| Single Ascending Dose Study of Two Liquidia Bupivacaine Formulations (NCT02982889) | Liquidia Technologies, Inc. | 2016-12-05 |
| Phase I Study of Cantrixil in Patients With Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer. (NCT02903771) | Kazia Therapeutics Limited | 2016-12-05 |
| Decitabine and Gemcitabine for Pancreatic Cancer and Sarcoma (NCT02959164) | Mohammed Milhem | 2016-12-05 |
| A Trial Evaluating the Safety & Efficacy of Intra-Tumoral Ipilimumab in Combination With Intra-venous Nivolumab in Patients With Metastatic Melanoma (NCT02857569) | Gustave Roussy, Cancer Campus, Grand Paris | 2016-12-05 |
| Pembrolizumab and Doxorubicin Hydrochloride in Treating Patients With Sarcoma That is Metastatic or Cannot Be Removed by Surgery (NCT02888665) | Fred Hutchinson Cancer Center | 2016-12-05 |
| A Study of LY3305677 in Healthy Participants (NCT02972645) | Eli Lilly and Company | 2016-12-05 |
| Pharmacokinetic, Safety and Tolerability Study of Altebrel in Healthy Male Subjects (NCT03273088) | AryoGen Pharmed Co. | 2016-12-04 |
| Bioequivalence of Two Different Sources of Eslicarbazepine Acetate (NCT03116321) | Bial - Portela C S.A. | 2016-12-03 |
| Trial to Find and Investigate a Safe Dose of F16IL2 and BI 836858 in Patients With AML Relapse After Allogeneic Hematopoietic Stem Cell Transplantation (NCT03207191) | Philogen S.p.A. | 2016-12-02 |
| Lower Dose Depo Provera® Contraceptive Injection (NCT02732418) | FHI 360 | 2016-12-02 |
| A Phase I, Two-part Study to Determine the Recommended Dose and Evaluate the Safety and Tolerability of a Novel Oral Arsenic Trioxide Formulation (ORH-2014) in Subjects With Advanced Hematological Disorders (NCT03048344) | Orsenix LLC | 2016-12-02 |
| HAL-MPE1 Safety and Tolerability Study (NCT02991885) | HAL Allergy | 2016-12-01 |
| Pharmacokinetic Drug-drug Interaction of CKD-330 and D086 (NCT03017950) | Chong Kun Dang Pharmaceutical | 2016-12-01 |
| A Phase 1 Study of KHK4083 in Healthy Volunteers and Subjects With Ulcerative Colitis (NCT02985593) | Kyowa Kirin Co., Ltd. | 2016-12-01 |