| A Study to Evaluate the Pharmacokinetics and Safety Between HIP2503 and HCP1306 in Healthy Volunteers (NCT07297693) | Hanmi Pharmaceutical Company Limited | 2025-12-19 |
| Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma (NCT07300241) | Neomorph, Inc | 2025-12-19 |
| Phase I Study of Preconditioning Radiation Therapy With IL-15 Transduced TGFBR2 KO CAR.TROP2-engineered Cord Blood-derived NK Cells in Patients With Advanced Head and Neck Cancer (RADIANCE-NK) (NCT07101432) | M.D. Anderson Cancer Center | 2025-12-19 |
| Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors (NCT07444814) | Whitehawk Therapeutics, Inc. | 2025-12-19 |
| Mezigdomide and Talquetamab in Relapsed and Refractory Multiple Myeloma (NCT07032714) | Massachusetts General Hospital | 2025-12-19 |
| Phase 1 Trial of Arginine Hydrochloride for the Management of Diabetic Ketoacidosis in Type 2 Diabetes (NCT07167693) | David K Carroll | 2025-12-19 |
| KXV01 Injection in Patients With Advanced Solid Tumor (Including Osteosarcoma and Sarcoma) (NCT07596693) | TCRx Therapeutics Co.Ltd | 2025-12-19 |
| Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS (NCT07287397) | Vector Y Therapeutics | 2025-12-19 |
| Phase 1/2 Study of MZ-1866, an AAV-9 Gene Therapy Delivered by Intracerebroventricular Injection to Participants With Pitt Hopkins Syndrome (NCT07135050) | Mahzi Therapeutics | 2025-12-19 |
| NEXUS Study: A Study to Test Single and Multiple Doses of MER511 Given to Adults With Graves' Disease (NCT07305818) | Merida Biosciences | 2025-12-19 |
| Clinical Trial of the Adsorbed Acellular Pertussis (Tricomponent) DTaP-Haemophilus Influenzae Type b (Conjugate)-ACYW135 Group Meningococcal (Conjugate) Combined Vaccine (NCT07203755) | CanSino Biologics Inc. | 2025-12-19 |
| Study to Assess the Effect of OCT-598 in Patients With Advanced Solid Tumors (NCT07358806) | Oscotec Inc. | 2025-12-18 |
| Safety and Pharmacokinetics of NM6603 in Chinese Patients With Advanced Solid Tumors (NCT07292038) | NucMito Pharmaceuticals Co. Ltd. | 2025-12-18 |
| A Study to Learn More About the Safety of BIIB145 and How it is Processed in the Body of Healthy Adult Participants (NCT07225517) | Biogen | 2025-12-18 |
| Impact of Exogenous Ketones on Sleep and Breathing in Healthy Volunteers (K-SLEEP) (NCT07224074) | Johns Hopkins University | 2025-12-18 |
| Small Cell Lung Cancer Irinotecan and CDC2-like Kinase Inhibition Trial (SLICK Trial) (NCT07155200) | Washington University School of Medicine | 2025-12-18 |
| A Clinical Trial Evaluating TQF3250 Capsules in Healthy Adult Subjects (NCT07327281) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2025-12-18 |
| A Clinical Trial of MK-1167 in Healthy Adults (MK-1167-010) (NCT07266818) | Merck Sharp & Dohme LLC | 2025-12-18 |
| Study of NXP900 With Osimertinib in Subjects With Advanced, EGFR-Mutated Non-Small Cell Lung Cancer (NCT07315113) | Nuvectis Pharma, Inc. | 2025-12-18 |
| Phase I/II Clinical Study of JMT108 Injection for the Treatment of Advanced Malignant Melanoma and Urinary Tract Tumors (NCT07280832) | Shanghai JMT-Bio Inc. | 2025-12-17 |
| A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMBD-501 in Patients With HER3-Expressing Solid Tumors (NCT06956690) | Hummingbird Bioscience | 2025-12-17 |
| A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of ABBV-243 in Healthy Adults. (NCT07306754) | AbbVie | 2025-12-17 |
| A Study of OTP-01, a Dual Paratopic PD-1/VEGFR2 Antibody, in Patients With Advanced Solid Tumors (NCT07266428) | Ottimo Pharma Limited | 2025-12-17 |
| A Study of REGN7041 for Active Noninfectious Uveitis in Adult Participants (NCT07218770) | Regeneron Pharmaceuticals | 2025-12-17 |
| Investigating the Pharmacokinetics of Petrelintide Using Different Drug Product Concentrations (NCT07338214) | Zealand Pharma | 2025-12-17 |
| Bioequivalence Study of Levetiracetam 1500 mg Coated Granules in Healthy, Male Subjects (NCT07393022) | Desitin Arzneimittel GmbH | 2025-12-17 |
| A Bioequivalence Study of Advil Tablet (Mini) (Ibuprofen 200 mg) Versus Advil Tablet (Ibuprofen 200 mg) in Healthy Adult Subjects Under Fasted Conditions and Bioavailability Assessment of Advil Tablet (Mini) Under Fed Conditions (NCT07345130) | HALEON | 2025-12-17 |
| Application of [68Ga]Ga-NI-FAPI-04 PET/CT Imaging in Fibroblast Activation Protein Related Diseases (NCT07464132) | Peking Union Medical College Hospital | 2025-12-17 |
| Ruxolitinib in Combination With CHOP Chemotherapy for the Treatment of Untreated Nodal T-Follicular Helper Cell Lymphomas (NCT07278856) | City of Hope Medical Center | 2025-12-16 |
| A Phase Ⅰ/Ⅱa Study of HMPL-A251 in Participants With Advanced or Metastatic HER2-expressing Solid Tumors (NCT07228247) | Hutchmed | 2025-12-16 |
| The KN510713 Study in Combination With mFOLFIRINOX (NCT07114861) | New Cancer Cure-Bio Co.,Ltd. | 2025-12-16 |
| A Research Study of a New Medicine NNC0363-1063 in Participants With Type 1 Diabetes (NCT07305805) | Novo Nordisk A/S | 2025-12-16 |
| Clinical Trial of TQB2922 Injection (Subcutaneous Injection) in Patients With Advanced Cancers (NCT07260708) | Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd. | 2025-12-16 |
| A Clinical Study of MK-4716 in People With Certain Solid Tumors (MK-4716-001) (NCT07247110) | Merck Sharp & Dohme LLC | 2025-12-16 |
| A Phase I Study to Assess LBL-047 in Healthy Adults and Patients With Systemic Lupus Erythematosus (NCT07323173) | Nanjing Leads Biolabs Co.,Ltd | 2025-12-16 |
| A Clinical Trial of Influenza Virus Split Vaccine for Individuals Aged 60 Years and Above (NCT07302256) | Shanghai Institute Of Biological Products | 2025-12-16 |
| Comparison Of Clinical Outcomes of Intraperitoneal Bupivacaine Instillation Versus Placebo as Preemptive Analgesia in Patients Undergoing Open Appendectomy (NCT07429448) | Sardar Umer Rehman | 2025-12-16 |
| DCSZ11 in Combination With Standard Therapy in Advanced or Metastatic Solid Tumors (NCT07035249) | West China Hospital | 2025-12-16 |
| Study of ENP-501 in Peanut-Allergic and Non-Allergic Participants (NCT07117669) | N-Fold, LLC | 2025-12-16 |
| A Trial of TER-1754 in Patients With Hereditary Hemorrhagic Telangiectasia (NCT07255846) | Terremoto Biosciences Inc. | 2025-12-15 |
| A Study to Investigate the Effect of a Low-fat Meal and Evening Dosing on KAI-7535 in Participants Living With Obesity or Overweight (NCT07294898) | Kailera | 2025-12-15 |
| A Phase Ia Study of KMY Tablets in Healthy Subjects (NCT07314541) | Lei Yunshang Group | 2025-12-15 |
| Sapu003 in Advanced mTOR-sensitive Solid Tumors (NCT07369505) | SAPU NANO (US) LLC | 2025-12-15 |
| Maximal Usage Pharmacokinetics and Safety Study of ARQ-154 Foam 0.3% in Pediatric Participants With Scalp and Body Psoriasis (NCT07340216) | Arcutis Biotherapeutics, Inc. | 2025-12-15 |
| A Trial to Compare the Extent to Which Maridebart Cafraglutide (AMG 133) is Made Available in the Body When Administered Using Two Subcutaneous Presentations (NCT07313761) | Amgen | 2025-12-15 |
| A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Oral F-02-2-Na Tablets in Adult Subjects (NCT07324434) | Guangdong Hengqin Novagains Biopharmaceutical Co., Ltd. | 2025-12-15 |
| Pharmacokinetic, Safety and Immunogenicity Study of New Process CMAB015 and Cosentyx in Healthy Volunteers (NCT07254325) | Taizhou Mabtech Pharmaceutical Co.,Ltd | 2025-12-15 |
| Autogenous Mesenchymal Stem Cell Culture-Derived Signalling Molecules as Enhancers of Bone Formation in Bone Grafting (NCT04998058) | Pontificia Universidade Católica do Rio Grande do Sul | 2025-12-15 |
| A Study to Evaluate the Effect of Itraconazole and Rifampin on the Drug Levels of AR-LDD (BMS-986365) in Healthy Adult Male Participants (NCT07242781) | Celgene | 2025-12-15 |
| Study of ASP2957 in Male Participants With X-linked Myotubular Myopathy Who Need Ventilators (NCT07052929) | Astellas Gene Therapies | 2025-12-15 |
| Safety and Immunogenicity Study of Three mRNAs Encoding HIV Immunogens in Adult Participants Without HIV and in Overall Good Health in South Africa. (NCT06694753) | International AIDS Vaccine Initiative | 2025-12-15 |
| Safety and Efficacy of the JAK1 Inhibitor Combined With Intensive Immunosuppressive Therapy in Severe Aplastic Anemia (NCT07297550) | Institute of Hematology & Blood Diseases Hospital, China | 2025-12-15 |
| A Study to Assess the Drug Levels and Safety of BMS-986435 in Participants With Normal Hepatic Function and Participants With Different Degrees of Hepatic Impairment (NCT07248839) | Bristol-Myers Squibb | 2025-12-15 |
| To Assess the Enzyme Inducing Effects of Carbamazepine on the PK of Mirdametinib in Healthy Participants (NCT07279233) | SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany | 2025-12-15 |
| T Cell Receptor Gene-Engineered and Dominant Negative TGF-β Receptor T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor (NCT07474168) | Zhejiang University | 2025-12-15 |
| Optical PD-1 and PD-L1 Imaging in Locally Advanced Esophageal Cancer Using Durvalumab-680LT and Nivolumab-800CW (NCT07196384) | University Medical Center Groningen | 2025-12-15 |
| A Study of Tolododekin Alfa (ANK-101) in Renal Allograft Recipients With High Risk Cutaneous Squamous Cell Carcinoma (NCT07100925) | Ankyra Therapeutics, Inc | 2025-12-15 |
| A Clinical Study of Dual-Target, Universal CAR-T Cell Therapy for Refractory Systemic Lupus Erythematosus (NCT07444307) | Hangzhou Qihan Biotech Co., Ltd. | 2025-12-15 |
| Pharmacokinetics and Safety Profiles of DA-1229_01 in Healthy Subjects at Fasting State (NCT07297940) | Dong-A ST Co., Ltd. | 2025-12-14 |
| Single-dose Pharmacokinetics of Pociredir in Participants With Sickle Cell Disease (NCT07431398) | Fulcrum Therapeutics | 2025-12-13 |
| A Phase Ib Trial Evaluating the Safety and Activity of Neoadjuvant Combination of Tislelizumab Plus FLOT for Resectable Esophagogastric Adenocarcinoma (NCT07059299) | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | 2025-12-12 |
| A Study to Assess the Safety, Tolerability, and Pharmacokinetics of a Single Ascending Dose of AZD0292 in Healthy Japanese Participants (NCT07222254) | AstraZeneca | 2025-12-12 |
| An Early Phase Trial of RPTR-1-201 in Advanced Solid Tumors (NCT07293754) | Repertoire Immune Medicines | 2025-12-12 |
| A Study to Evaluate ALN-4285 in Adult Healthy Volunteers (NCT07295717) | Alnylam Pharmaceuticals | 2025-12-12 |
| A Study to Learn How the Body Processes BIIB141 (Omaveloxolone) When Taken as a Capsule or as a Tablet Dissolved in Liquid, and to Learn About Its Safety in Healthy Adults Ages 18 to 55 (NCT07297199) | Biogen | 2025-12-12 |
| Safety and Psychological Effects of Psilocybin and D-Serine Formulation in Healthy Volunteers (NCT07079930) | Hadassah Medical Organization | 2025-12-11 |
| A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors (NCT07226349) | BeOne Medicines | 2025-12-11 |
| Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B) (NCT07027839) | National Institute of Mental Health (NIMH) | 2025-12-11 |
| Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/ Refractory Small Cell Lung Cancer (NCT06922539) | SciTech Development, Inc. | 2025-12-11 |
| An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors (NCT07222267) | BeOne Medicines | 2025-12-11 |
| A Trial to Evaluate the Absolute Bioavailability of Cenerimod in Healthy Male Participants (NCT07301723) | Viatris Innovation GmbH | 2025-12-11 |
| Study of Food Effect on Pharmacokinetics of HMPL-523 Acetate Tablets (NCT07348133) | Hutchmed | 2025-12-11 |
| A Study to Evaluate the PK Similarity of AK112 in Healthy Chinese Male Subjects (NCT07340476) | Akeso | 2025-12-11 |
| A Study to Learn How Different Amounts of the Study Medicine Called PF-07985631 Are Tolerated and Act in the Body in Healthy Adults (NCT07235150) | Pfizer | 2025-12-11 |
| A Phase I Trial on the Relative Bioavailability and Food Effect of HRS-1893 Tablets in Healthy Subjects (NCT07272330) | Shandong Suncadia Medicine Co., Ltd. | 2025-12-11 |
| A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults (NCT07290036) | UCB Biopharma SRL | 2025-12-10 |
| BTM-3566 in Advanced Solid Tumors (NCT07266285) | Bantam Pharmaceuticals | 2025-12-10 |
| The Safety and Efficacy of Daratumumab in Patients With Refractory Aplastic Anemia (NCT07287228) | Institute of Hematology & Blood Diseases Hospital, China | 2025-12-10 |
| A Study to Investigate Safety, Tolerability, and Pharmacokinetics of AZD3974 in Healthy Participants (NCT07290283) | AstraZeneca | 2025-12-10 |
| CATALINA-4: A Study to Investigate the Safety and Efficacy of TORL-1-23 With Chemotherapy Given Before Initial Surgery in Women With Advanced Stage Ovarian Cancer (NCT07322094) | TORL Biotherapeutics, LLC | 2025-12-10 |
| A Study of Lutetium [177Lu]-BL-ARC001 in Patients With Locally Advanced or Metastatic Lung Cancer, Breast Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors (NCT07274852) | Sichuan Baili Pharmaceutical Co., Ltd. | 2025-12-10 |
| The Effects of Vonoprazan Fumarate on DGF Incidence in DD Kidney Transplant Recipients (NCT07275632) | First Affiliated Hospital of Chongqing Medical University | 2025-12-10 |
| A Study of BL-M24D1 in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors (NCT07232524) | Sichuan Baili Pharmaceutical Co., Ltd. | 2025-12-10 |
| A Study of ABSK061 to Assess Safety, Tolerability, Pharmacokinetics, and Efficacy in Children With Achondroplasia (NCT07297875) | Abbisko Therapeutics Co, Ltd | 2025-12-10 |
| Ketamine-Enhanced Therapy for Individuals With Alcohol Use Disorder and Depression: A Pilot Study (KET-DUAL) (NCT07247370) | South West Sydney Local Health District | 2025-12-10 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of GenSci140 in Participants With Advanced Solid Tumors (NCT07251166) | Changchun GeneScience Pharmaceutical Co., Ltd. | 2025-12-10 |
| Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-581 in Healthy Participants (NCT07283770) | Vertex Pharmaceuticals Incorporated | 2025-12-09 |
| Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid / Ezetimibe, and Atorvastatin (NCT07268625) | Daiichi Sankyo | 2025-12-09 |
| A Clinical Study Assessing the Subcutaneous Formulation of TQB2934 for Injection in Subjects With Malignant Plasma Cell Tumors (NCT07179679) | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | 2025-12-09 |
| A Phase 1, Open-Label, Parallel-Group, Single-Dose Study To Compare The Pharmakokinetics Of TNX-102 SL (Cyclobenzaprine Hydrochloride Sublingual Tablet) In Non-Elderly Versus Elderly Participants (NCT07413367) | Tonix Pharmaceuticals, Inc. | 2025-12-09 |
| An Open-label Study of AZD0120 in Adults With Multiple Sclerosis (NCT07224373) | AstraZeneca | 2025-12-09 |
| A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003) (NCT07222488) | Merck Sharp & Dohme LLC | 2025-12-09 |
| Safety and Efficacy of CD19 Chimeric Antigen Receptor T-Cell (CAR-T) in the Treatment of Refractory Membranous Nephropathy (NCT07266181) | The First Affiliated Hospital of Air Force Medicial University | 2025-12-08 |
| A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of UCB5285 in Healthy Study Participants (NCT07286682) | UCB Biopharma SRL | 2025-12-08 |
| STM-06: POLARIS-POlymetastic Lesion Ablative Radiotherapy With Immunotherapy Study (NCT07269080) | University of Illinois at Chicago | 2025-12-08 |
| A Study of the Effect of Diltiazem on the Plasma Levels of Nemtabrutinib (MK-1026-022) (NCT07232589) | Merck Sharp & Dohme LLC | 2025-12-08 |
| Cirtuvivint/Olaparib in Breast Cancer Susceptibility Gene/Homologous Recombination Deficiency Platinum Resistant Ovarian Cancer (NCT06856499) | University of Colorado, Denver | 2025-12-08 |
| EZH2 Inhibitor, Tulmimetostat, and PD-1 Blockade for Treatment of Advanced Non-small Cell Lung Cancer (NCT05467748) | VA Office of Research and Development | 2025-12-08 |
| A Study to Evaluate the Safety, Tolerability, and Pharmacokinetic of IBI3011 (NCT07295496) | Innovent Biologics (Suzhou) Co. Ltd. | 2025-12-08 |
| A Study to Evaluate the Safety, Tolerability and PK of SK-09 (NCT07267026) | Consun Pharmaceutical Group | 2025-12-08 |