| A Study to Compare the Macitentan-tadalafil Fixed Dose Combination Tablet Relative to the Concomitant Administration of the Reference Tablets of Macitentan and Tadalafil in Healthy Subjects (NCT03215966) | Actelion | 2017-08-07 |
| Safety,Tolerability and MTD KA2507 (HDAC6 Inhibitor) in Patients With Solid Tumours (NCT03008018) | Karus Therapeutics Limited | 2017-08-07 |
| Radiolabeled Study to Determine the Mass Balance of [14C] MGL-3196 (NCT03220165) | Madrigal Pharmaceuticals, Inc. | 2017-08-06 |
| Dose-escalation Study of Birinapant and Pembrolizumab in Solid Tumors (NCT02587962) | Medivir | 2017-08-04 |
| Pilot Study of T-APCs Following CAR T Cell Immunotherapy for CD19+ Leukemia (NCT03186118) | Seattle Children's Hospital | 2017-08-04 |
| Blinatumomab & Pembrolizumab for Adults With Relapsed/Refractory B-cell ALL With High Marrow Lymphoblasts (NCT03160079) | University of California, San Diego | 2017-08-04 |
| Selumetinib and Olaparib in Solid Tumors (NCT03162627) | M.D. Anderson Cancer Center | 2017-08-04 |
| Study of Adoptive Cellular Therapy Using Autologous T Cells Transduced With Lentivirus to Express a CD33 Specific Chimeric Antigen Receptor in Patients With Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia (NCT03126864) | M.D. Anderson Cancer Center | 2017-08-04 |
| Pembrolizumab (Immunotherapy Drug) in Combination With Guadecitabine and Mocetinostat (Epigenetic Drugs) for Patients With Advanced Lung Cancer. (NCT03220477) | Memorial Sloan Kettering Cancer Center | 2017-08-04 |
| A Study of Carboplatin and Paclitaxel Chemotherapy With Nivolumab With or Without Ipilimumab in Patients With Ovarian Cancer (NCT03245892) | Memorial Sloan Kettering Cancer Center | 2017-08-04 |
| Safety and Efficacy Trial of AAV Gene Therapy in Patients With CNGA3 Achromatopsia (A Clarity Clinical Trial) (NCT02935517) | Beacon Therapeutics | 2017-08-03 |
| Dose Escalation Trial of Intra-Tumoral Injection of NIS Measles Virus in Combination With Atezolizumab (NCT02919449) | Vyriad, Inc. | 2017-08-03 |
| A Study of Nivolumab in Combination With Ipilimumab in Chinese Participants With Previously Treated Advanced or Recurrent Solid Tumors (NCT03195478) | Bristol-Myers Squibb | 2017-08-02 |
| Tear Concentrations and Pharmacokinetics of Azithromycin Eye Drops in Healthy Volunteers (NCT03252067) | Beijing Tongren Hospital | 2017-08-02 |
| Study of AZD5991 Alone or in Combination With Venetoclax in Relapsed or Refractory Haematologic Malignancies. (NCT03218683) | AstraZeneca | 2017-08-02 |
| A Two-part Study to Compare a Tablet and Capsule Formulation of GSK2838232 With and Without Food, and to Assess the Safety and Drug Levels of Repeated Once-daily Doses of GSK2838232 Without Ritonavir (NCT03234036) | GlaxoSmithKline | 2017-08-02 |
| Copanlisib, Letrozole, and Palbociclib in Treating Patients With Hormone Receptor Positive HER2 Negative Stage I-IV Breast Cancer (NCT03128619) | Jonsson Comprehensive Cancer Center | 2017-08-02 |
| QUILT-3.028: Study of haNK™ for Infusion in Subjects With Metastatic or Locally Advanced Solid Tumors (NCT03027128) | ImmunityBio, Inc. | 2017-08-02 |
| Avelumab, Utomilumab, Anti-OX40 Antibody PF-04518600, and Radiation Therapy in Treating Patients With Advanced Malignancies (NCT03217747) | M.D. Anderson Cancer Center | 2017-08-02 |
| Investigate the Effect of Food on the Pharmacokinetics of JLP-1310 in Healthy Male Volunteers (NCT02449187) | Jeil Pharmaceutical Co., Ltd. | 2017-08-02 |
| Drug-drug-interaction Study to Assess the Effect of Darolutamide on the Pharmacokinetics of Probe Substrates of CYP3A4 and P-gp in Healthy Male Volunteers (NCT03237416) | Bayer | 2017-08-02 |
| Blinatumomab Consolidation Post Autologous Stem Cell Transplantation in Patients With Diffuse Large B-Cell Lymphoma (DLBCL) (NCT03072771) | Washington University School of Medicine | 2017-08-01 |
| COZMOS:Phase I/Ib Trial of Combined 5'Azacitidine and Carboplatin for Recurrent/Refractory Pediatric Brain/Solid Tumors (NCT03206021) | The Hospital for Sick Children | 2017-08-01 |
| Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stromal Cell Product (RegStem) (NCT03007576) | EMO Biomedicine Corporation | 2017-08-01 |
| Prophylactic Antibiotics After Cesarean (NCT03187106) | The University of Texas Medical Branch, Galveston | 2017-08-01 |
| Neo-MASCT Immunotherapy for Advanced NSCLC. (NCT03205930) | The First People's Hospital of Lianyungang | 2017-08-01 |
| Relative Bioavailability of Gantenerumab Produced by G4 Process Versus G3 Process Following Subcutaneous (SC) Injection in Healthy Participants (NCT03236844) | Hoffmann-La Roche | 2017-08-01 |
| Glucosamine and Chondroitin in Preventing Inflammation in Overweight Patients (NCT03827161) | Fred Hutchinson Cancer Center | 2017-08-01 |
| Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma (NCT02704858) | Neonc Technologies, Inc. | 2017-08-01 |
| The ICON Study: Outcomes After FMT for Patients With IBD and CDI (NCT03106844) | Brigham and Women's Hospital | 2017-08-01 |
| Autologous Adipose-derived Regenerative Cells Injection for Treatment of Radiation-induced Rectovaginal Fistula (NCT03643614) | South Ural State Medical University | 2017-08-01 |
| Cognitive and Psychophysiological Effects of Delta-9-Tetrahydrocannabinol in Bipolar Disorder (NCT03206463) | Yale University | 2017-08-01 |
| Grading Versus Classic Inferior Oblique Anterior Transposition in Patient With Asymmetric Dissociated Vertical Deviation (NCT03135938) | Shahid Beheshti University of Medical Sciences | 2017-08-01 |
| Study to Evaluate the Pharmacokinetics and Pharmacodynamics of JMI-001 (NCT03183297) | Sen-Jam Pharmaceutical | 2017-08-01 |
| Treatment With Nivolumab at the Fixed Dose 40 mg (Nivo40) in Patients With Relapsed/Refractory Hodgkins Lymphoma (NCT03343665) | St. Petersburg State Pavlov Medical University | 2017-08-01 |
| The Effect of Fractional Co2 Laser Either With Tacrolimus, Calcipotriol or NB-UVB in Stable Generalized Vitiligo (NCT03234673) | Assiut University | 2017-08-01 |
| Central Pain Study for ABX-1431 (NCT03138421) | Abide Therapeutics | 2017-08-01 |
| Safety and Efficacy of Dual Specificity CD19 and CD22 CAR-T Cell Immunotherapy in R/R Acute B Lymphoblastic Leukemia (NCT04094766) | Second Affiliated Hospital of Xi'an Jiaotong University | 2017-08-01 |
| A Study To Assess The Safety, Tolerability, And Pharmacokinetics (PK) Of Multiple Doses Of PF-06865571 In Healthy, Including Overweight And Obese, Adult Subjects (NCT03230383) | Pfizer | 2017-08-01 |
| Mirabegron For Erectile Dysfunction (NCT02916693) | Johns Hopkins University | 2017-08-01 |
| Bioequivalence Study Between GR37547 500 Milligrams (mg) Tablet Versus Ciprofloxacin 500 mg Tablet Reference Product in Healthy Adult Subjects (NCT03150082) | GlaxoSmithKline | 2017-08-01 |
| Intranasal Oxytocin for Infants With Prader-Willi Syndrome (NCT03245762) | University of Florida | 2017-08-01 |
| Study of Pomaglumetad and Methamphetamine (NCT03106571) | University of California, Los Angeles | 2017-08-01 |
| A Phase 1b Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Doses of JNJ-64565111 in Participants With Type 2 Diabetes Mellitus (NCT03235219) | Janssen Research & Development, LLC | 2017-08-01 |
| Androgen Reduction in Congenital Adrenal Hyperplasia, Phase 1 (NCT02574910) | University of Texas Southwestern Medical Center | 2017-08-01 |
| Pembrolizumab in Combination With Radiotherapy in Locally Advanced Non-Small Cell Lung Cancer (NSCLC) (NCT03245177) | Prof Corinne Faivre-Finn | 2017-08-01 |
| Fluorescence Targeted Pelvic Lymph Node Mapping (NCT03204994) | Oxford University Hospitals NHS Trust | 2017-08-01 |
| Remote Ischaemic Conditioning in Endovascular Recanalization for Proximal Anterior Circulation Occlusion Study (NCT03152799) | University College, London | 2017-08-01 |
| Pembrolizumab Cyclophosphamide and Lenalidomide for Patients With Relapsed Multiple Myeloma (NCT03191981) | University of Leeds | 2017-08-01 |
| Intranasal Insulin for the Treatment of HAND (NCT03081117) | Johns Hopkins University | 2017-08-01 |
| A Safety and Tolerability Study of Pemigatinib in Japanese Subjects With Advanced Malignancies - (FIGHT-102) (NCT03235570) | Incyte Corporation | 2017-08-01 |
| A Study of TAK-659 as a Single Agent in Adult East Asian Participants With Non-Hodgkin Lymphoma (NHL) (NCT03238651) | Calithera Biosciences, Inc | 2017-08-01 |
| The Effect of Chlorohexidine Gel on Tissue Healing Following Surgical Exposure of Dental Implants (NCT03195582) | Rambam Health Care Campus | 2017-08-01 |
| 3RD GENERATION GD2 SPECIFIC CHIMERIC ANTIGEN RECEPTOR TRANSDUCED AUTOLOGOUS NATURAL KILLER T-CELLS FOR NEUROBLASTOMA (NCT02439788) | Baylor College of Medicine | 2017-08-01 |
| Limbus-derived Stem Cells for Prevention of Postoperative Corneal Haze (NCT03295292) | L.V. Prasad Eye Institute | 2017-08-01 |
| Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD22 (NCT03185494) | Chinese PLA General Hospital | 2017-08-01 |
| A 24-month Phase 1 Pilot Study of AADvac1 in Patients With Non Fluent Primary Progressive Aphasia (NCT03174886) | Axon Neuroscience SE | 2017-07-31 |
| Study to Investigate the Pharmacokinetics, Safety, and Tolerability of BMT101 in Healthy Male Volunteers (NCT03133130) | Hugel | 2017-07-31 |
| Driving Simulation to Assess Non-Sedative Effects of Tolperisone (NCT03353922) | Neurana Pharmaceuticals, Inc. | 2017-07-31 |
| Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemia (NCT03104491) | Leland Metheny | 2017-07-31 |
| Gene Therapy for X-linked Retinitis Pigmentosa (XLRP) - Retinitis Pigmentosa GTPase Regulator (RPGR) (NCT03252847) | MeiraGTx UK II Ltd | 2017-07-31 |
| Safety and Dose-Finding Study of DTX301 (scAAV8OTC) in Adults With Late-Onset Ornithine Transcarbamylase (OTC) Deficiency (NCT02991144) | Ultragenyx Pharmaceutical Inc | 2017-07-31 |
| Trial of Taselisib in Overgrowth (NCT03290092) | Centre Hospitalier Universitaire Dijon | 2017-07-31 |
| Regorafenib in Combination With TAS-102 in Subjects With Metastatic Colorectal Cancer Who Have Progressed After Standard Therapy (NCT03305913) | AIO-Studien-gGmbH | 2017-07-31 |
| Safety, Tolerability, Pharmacokinetics, and Efficacy of AZD2811 Nanoparticles as Monotherapy or in Combination in Acute Myeloid Leukemia Participants. (NCT03217838) | AstraZeneca | 2017-07-31 |
| Safety, Clinical Activity, Pharmacokinetics (PK) and Pharmacodynamics Study of GSK2879552, Alone or With Azacitidine, in Subjects With High Risk Myelodysplastic Syndromes (MDS) (NCT02929498) | GlaxoSmithKline | 2017-07-31 |
| Cyclophosphamide and Alemtuzumab In Lymphoma (NCT03132584) | Dana-Farber Cancer Institute | 2017-07-30 |
| Sorafenib, Busulfan and Fludarabine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant (NCT03247088) | M.D. Anderson Cancer Center | 2017-07-30 |
| Consolidation Therapy in Patients With Metastatic Solid Malignancies (NCT02705703) | Kiromic BioPharma Inc. | 2017-07-28 |
| BATs Treatment for Pancreatic Cancer, Phase Ib/II (NCT03269526) | University of Virginia | 2017-07-28 |
| Therapy for Progressive and/or Refractory Hematologic Malignancies (NCT02223312) | Kiromic BioPharma Inc. | 2017-07-28 |
| Safety, Tolerability & Pharmacokinetics of LEVI-04 in Healthy Volunteers and Patients With Osteoarthritis Knee Pain (NCT03227796) | Levicept | 2017-07-28 |
| Cyclophosphamide, TAPA-Pulsed Dendritic Cell Therapy and Imiquimod in Progressive and/or Refractory Solid Malignancies (NCT02224599) | Kiromic BioPharma Inc. | 2017-07-28 |
| Study Assessing PTI-428 Safety, Tolerability, and Pharmacokinetics in Subjects With Cystic Fibrosis on KALYDECO® as Background Therapy (NCT03258424) | Proteostasis Therapeutics, Inc. | 2017-07-28 |
| Consolidation Therapy in Patients With Hematologic Malignancies (NCT02709993) | Kiromic BioPharma Inc. | 2017-07-28 |
| Putative Cognitive Enhancer VU319 (NCT03220295) | Vanderbilt University | 2017-07-28 |
| Study of Multiple-dose Kukoamine B Mesilate in Sepsis Patients (NCT03237728) | Tianjin Chasesun Pharmaceutical Co., LTD | 2017-07-28 |
| Evaluation of Safety and Tolerability of Single Rising Doses of BI 473494 in Healthy Subjects (NCT03195088) | Boehringer Ingelheim | 2017-07-27 |
| Study of E7386 in Participants With Selected Advanced Neoplasms (NCT03264664) | Eisai Inc. | 2017-07-27 |
| A Trial to Evaluate the Safety and Efficacy of the Combination of the Oncolytic Immunotherapy Pexa-Vec With the PD-1 Receptor Blocking Antibody Nivolumab in the First-line Treatment of Advanced Hepatocellular Carcinoma (HCC) (NCT03071094) | Transgene | 2017-07-27 |
| A Study of Durvalumab (Anti-PDL1) Plus Radiation Therapy for the Treatment of Solitary Bone Plasmacytoma (NCT03196401) | Memorial Sloan Kettering Cancer Center | 2017-07-27 |
| A Phase 1 Study of CD22-CAR TCell Immunotherapy for CD22+ Leukemia and Lymphoma (NCT03244306) | Seattle Children's Hospital | 2017-07-27 |
| A Study to Evaluate the Pharmacokinetics of Entinostat in Adult Subjects With Normal and Impaired Renal Function (NCT03192111) | Syndax Pharmaceuticals | 2017-07-27 |
| Enhancement of Bone Regeneration and Healing in the Extremities by the Use of Autologous BonoFill-II (NCT03024008) | BonusBio Group Ltd | 2017-07-27 |
| Study of Entospletinib (ENTO) in Newly Diagnosed DLBCL Patients With aaIPI>=1 Treated by Chemiotherapy (NCT03225924) | The Lymphoma Academic Research Organisation | 2017-07-26 |
| Trial to Evaluate the Safety, Immunogenicity and Protective Efficacy of Three or Five Administrations of GAP3KO Sporozoites (NCT03168854) | National Institute of Allergy and Infectious Diseases (NIAID) | 2017-07-26 |
| NovoTTF-200A and Temozolomide Chemoradiation for Newly Diagnosed Glioblastoma (NCT03232424) | Hackensack Meridian Health | 2017-07-26 |
| Safety, Pharmacokinetics and Pharmacodynamics of Intranasal Dexmedetomidine in Healthy Subjects (NCT03293277) | Jiangsu HengRui Medicine Co., Ltd. | 2017-07-26 |
| Type 1 Diabetes Data Acquisition and Transfer Adherence Study (NCT03228004) | University of Florida | 2017-07-26 |
| An Evaluation of Tilmanocept by IV Injection Using SPECT/CT vs PET Imaging in Subjects With Liver Metastases. (NCT03029988) | Navidea Biopharmaceuticals | 2017-07-26 |
| Evaluation of the Safety and Tolerability of Niraparib With Everolimus in Advanced Gynecologic Malignancies and Breast (NCT03154281) | Avera McKennan Hospital & University Health Center | 2017-07-26 |
| A Study of the Safety, Tolerability, and Pharmacokinetics of SM04690 Injectable Suspension Following Single Intradiscal Injection in Subjects With Degenerative Disc Disease (NCT03246399) | Biosplice Therapeutics, Inc. | 2017-07-26 |
| Trastuzumab and Pertuzumab in Combination With Tocilizumab in Subjects With Metastatic HER2 Positive Breast Cancer Resistant to Trastuzumab (NCT03135171) | University of Michigan Rogel Cancer Center | 2017-07-26 |
| Genetically Engineered PBMC and PBSC Expressing NY-ESO-1 TCR After a Myeloablative Conditioning Regimen to Treat Patients With Advanced Cancer (NCT03240861) | Jonsson Comprehensive Cancer Center | 2017-07-26 |
| Pharmacokinetics of Lu AF35700 in Subjects With Renal Impairment (NCT03241147) | H. Lundbeck A/S | 2017-07-25 |
| Intranasal (NAS) Ketamine for Cancer Pain (NCT03146806) | Emory University | 2017-07-25 |
| Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AJM347 in Healthy Male Caucasian and Japanese Subjects in the Fasted and Fed State (NCT03133468) | EA Pharma Co., Ltd. | 2017-07-25 |
| Bacterial Biofilms in Reconstructive Breast Prostheses Following Mastectomy (NCT03213249) | Washington University School of Medicine | 2017-07-25 |
| To Assess the Safety of Continuous IV Administration of Plerixafor and Assess Impact on the Immune Microenvironment in Patients With Pancreatic, Ovarian and Colorectal Adenocarcinomas (NCT03277209) | Weill Medical College of Cornell University | 2017-07-25 |
| Peripheral Blood Stem Cell Collection for Sickle Cell Disease (SCD) Patients (NCT03226691) | National Heart, Lung, and Blood Institute (NHLBI) | 2017-07-25 |