| CD19/CD22-targeted Chimeric Antigen Receptor Engineered T Cell (CART) in B-Cell Acute Lymphoblastic Leukemia. (NCT03614858) | Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd | 2017-09-01 |
| A Study Of Ursolic Acid For Primary Sclerosing Cholangitis (NCT03216876) | University of California, Davis | 2017-09-01 |
| Study to Evaluate Safety and MTD of Epidural Resiniferatoxin Injection for Treatment of Intractable Cancer Pain (NCT03226574) | Sorrento Therapeutics, Inc. | 2017-09-01 |
| CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells With or Without NKTR-255 in Adults With Recurrent or Refractory B Cell Malignancies (NCT03233854) | Stanford University | 2017-09-01 |
| A Comparison of Plasma Concentrations of Hydrocodone and Acetaminophen After Administration of Different Amounts of Tablets of a New and a Marketed Tablet Formulation in Healthy Adults (NCT03137030) | Grünenthal GmbH | 2017-09-01 |
| Study of HL-085 in NRAS Mutant Advanced Melanoma (NCT03973151) | Shanghai Kechow Pharma, Inc. | 2017-09-01 |
| Study of SXL01 in Patients With Metastatic Castration-Resistant Prostate Cancer (PROSTIRNA) (NCT02866916) | Institut Claudius Regaud | 2017-09-01 |
| Treatment for Clostridium-difficile Infection With IMM529 (NCT03065374) | Immuron Ltd. | 2017-09-01 |
| Clinical Trial of BP1001 (Liposomal Grb2 Antisense Oligonucleotide) in Combination With Dasatinib in Patients With Ph + CML Who Have Failed TKI, Ph+ AML, Ph+ MDS (NCT02923986) | Bio-Path Holdings, Inc. | 2017-09-01 |
| A Comparison of Plasma Concentrations of Hydrocodone and Acetaminophen After Administration of a New and a Marketed Tablet Formulation Under Fasted and Fed Conditions in Healthy Adults (NCT03137017) | Grünenthal GmbH | 2017-09-01 |
| Pharmacokinetics and Dosimetry of Tc 99m Tilmanocept Following a Single Intravenous Dose Administration in Male and Female Subjects Diagnosed With Rheumatoid Arthritis (RA) (NCT03241446) | Navidea Biopharmaceuticals | 2017-09-01 |
| Multimodal Sleep Pathway for Shoulder Arthroplasty (NCT03269760) | University of California, San Francisco | 2017-09-01 |
| Safety and Tolerability of Perampanel in Cervical Dystonia (NCT02131467) | University Health Network, Toronto | 2017-09-01 |
| A Phase 1 Study to Investigate Axatilimab Alone or in Combination With Durvalumab in Patients With Solid Tumors (NCT03238027) | Syndax Pharmaceuticals | 2017-09-01 |
| Pioglitazone Therapy for Chronic Granulomatous Disease (NCT03080480) | Children's Hospital of Fudan University | 2017-09-01 |
| ONE-SHOT Trial - Ultra-hypofractionated Single-dose SBRT for Prostate Cancer (NCT03294889) | University Hospital, Geneva | 2017-09-01 |
| Patient Driven Recovery With Nalmefene and Coaching (NCT03279562) | Yale University | 2017-09-01 |
| Stromal Vascular Fraction From Lipoaspirate to Treatment of Chronic Non-healing Wound (NCT03882983) | Antria | 2017-09-01 |
| NP001, Alzheimer's Disease, and Blood Markers of Inflammation (NCT03179501) | Beau Nakamoto | 2017-09-01 |
| The Effects of Folic Acid on Sudanese Women With Polycystic Ovary Syndrome (NCT03268733) | University of Khartoum | 2017-09-01 |
| The Effect of BMS-986165 Combined With an Oral Contraceptive (Ethinyl Estradiol/Norethindrone) in Healthy Female Patients (NCT03262727) | Bristol-Myers Squibb | 2017-09-01 |
| Pharmacokinetics (PK) and Safety of a Single Intravenous (IV) Dose of MK-3866 in Participants With Impaired Renal Function and in Healthy Controls (MK-3866-005) (NCT03259087) | Merck Sharp & Dohme LLC | 2017-09-01 |
| Efficacy and Safety of Colistin Based Antibiotic Therapy (NCT04764058) | Ain Shams University | 2017-09-01 |
| Phase Ib/II of TG4001 and Avelumab in HPV16 Positive R/M Cancers (NCT03260023) | Transgene | 2017-09-01 |
| The Breast Surgery EnLight and LightPath Imaging System Study (NCT02151071) | Lightpoint Medical Limited | 2017-09-01 |
| Effect of Different Concentrations of Lidocaine in Relieving Pain in Wide Awake Hand Surgery Using Tumescence (NCT04692896) | King Edward Medical University | 2017-09-01 |
| Safety and Efficacy Evaluation of Decitabine With R-GDP (NCT03535753) | Beijing Immunochina Medical Science & Technology Co., Ltd. | 2017-09-01 |
| Safety and Tolerability of GX-G6 in Healthy Male Subjects (NCT03651466) | Genexine, Inc. | 2017-08-31 |
| A "Window Trial" on Boswellia for Breast Cancer Primary Tumors (NCT03149081) | Medical University of South Carolina | 2017-08-31 |
| Idronoxil Suppository Combine With Radiotherapy for Metastatic Prostate Cancer (NCT03041285) | Royal North Shore Hospital | 2017-08-31 |
| A Study of Lasmiditan and Propranolol in Healthy Participants (NCT03270644) | Eli Lilly and Company | 2017-08-31 |
| This Study Tests Whether Taking the Medicines Empagliflozin, Linagliptin, and Metformin Together in 1 Pill is the Same as Taking Them in Separate Pills. The Study is Done in Healthy Men and Women and Measures the Amount of Each Medicine in the Blood (NCT03259490) | Boehringer Ingelheim | 2017-08-31 |
| A Study of Venetoclax and ABBV-838 Combination Therapy With Dexamethasone in Participants With Multiple Myeloma Whose Cancer Has Come Back or Had No Response to Recent Cancer Treatment (NCT02951117) | AbbVie | 2017-08-31 |
| Study to Evaluate the Safety, Preliminary Efficacy and Pharmacokinetics of 3810 (NCT03260179) | Haihe Biopharma Co., Ltd. | 2017-08-31 |
| A Study to Assess the Effect of Plazomicin on the Pharmacokinetics of Metformin (NCT03270553) | Achaogen, Inc. | 2017-08-31 |
| DCreg in Living Donor Liver Transplantation (NCT03164265) | Angus W. Thomson PhD DSc | 2017-08-30 |
| A Trial of HTI-1090 in Subjects With Advanced Solid Tumors (NCT03208959) | Atridia Pty Ltd. | 2017-08-30 |
| A Study of IMU-131(HER-Vaxx) and Chemotherapy Compared to Chemotherapy Only in Patients With HER2 Positive Advanced Gastric Cancer (NCT02795988) | Imugene Limited | 2017-08-30 |
| Safety and Pharmacokinetic Study of PF-06651600 in Japanese Healthy Volunteers (NCT03232905) | Pfizer | 2017-08-30 |
| Use of T-allo10 in Hematopoietic Stem Cell Transplantation (HSCT) for Blood Disorders (NCT03198234) | Roncarolo, Maria Grazia, MD | 2017-08-30 |
| Does Hyaluronic Acid Affect Periodontal Treatment? (NCT03754010) | Yuzuncu Yil University | 2017-08-30 |
| Midodrine Hydrochloride in Early Sepsis (NCT03129542) | Mayo Clinic | 2017-08-30 |
| CAR-T Cells for Relapsed or Refractory Haematopoietic and Lymphoid Malignancies (NCT03312205) | Hebei Senlang Biotechnology Inc., Ltd. | 2017-08-29 |
| A Phase 1 Study to Evaluate Safety, Tolerability, PK, and PK Interactions of TBA-7371 (NCT03199339) | Global Alliance for TB Drug Development | 2017-08-29 |
| A Depot Formulation of Sunitinib Malate (GB-102) in Subjects With Neovascular (Wet) Age-related Macular Degeneration (NCT03249740) | Graybug Vision | 2017-08-29 |
| Evaluation of the Safety and the Tolerability of Durvalumab Plus Tremelimumab Combined With FOLFOX in mCRC (NCT03202758) | Centre Georges Francois Leclerc | 2017-08-29 |
| DUSA: Cyclic PDT for the Prevention of AK & NMSC in Solid Organ Transplant Recipients (NCT03110159) | Medical Dermatology Specialists | 2017-08-29 |
| Study to Assess the Safety & Tolerability of NOV140101(IDX-1197) in Patients With Advanced Solid Tumors (NCT03317743) | Idience Co., Ltd. | 2017-08-29 |
| Addressing Unmet Basic Needs to Improve Adherence Among Women With an Abnormal Pap (NCT03317470) | Washington University School of Medicine | 2017-08-29 |
| PEN-866 in Patients With Advanced Solid Malignancies (NCT03221400) | Tarveda Therapeutics | 2017-08-29 |
| Unesbulin in Women With Ovarian Cancer Receiving Neoadjuvant Chemotherapy (NCT03206645) | University of Oklahoma | 2017-08-28 |
| Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Donidalorsen (IONIS-PKK-LRx) Administered Subcutaneously to Healthy Volunteers (NCT03263507) | Ionis Pharmaceuticals, Inc. | 2017-08-28 |
| A Study of Oral Nitrate in Adults With Pulmonary Hypertension With Heart Failure and Preserved Ejection Fraction (NCT02980068) | Gladwin, Mark, MD | 2017-08-28 |
| A Safety, Tolerability, and Pharmacokinetics Study of a Single Intravenous Injection of Recombinant Coagulation Factor VIII Fc - Von Willebrand Factor - XTEN Fusion Protein (rFVIIIFc-VWF-XTEN) (BIVV001) in Previously Treated Adults With Severe Hemophilia A (EXTEN-A) (NCT03205163) | Bioverativ, a Sanofi company | 2017-08-28 |
| Absorption and Tolerability Studies of an Emulsion Containing the Coconut Oil-derived Glycerol Tridecanoate in Healthy Men (NCT03255889) | National University Hospital, Singapore | 2017-08-28 |
| Next Science Antimicrobial Mouth Rinse Study (NCT03154021) | University of Florida | 2017-08-28 |
| A Study to Evaluate Safety, Pharmacokinetics, and Clinical Activity of Combination of RO6870810 and Venetoclax, With or Without Rituximab, in Participants With Relapsed/Refractory DLBCL and/or High-Grade B-Cell Lymphoma and/or High Grade B-Cell Lymphoma With MYC and/or BCL2 and/or BCL6 (NCT03255096) | Hoffmann-La Roche | 2017-08-28 |
| Chinese Herb for the Treatment of Depression and Anxiety Disorders (NCT03323697) | Mazra Mental Health Center | 2017-08-28 |
| MEN1309 I.v. Infusion in Pts With CD205-positive Metastatic Solid Tumors and Relapsed or Refractory NHL Ph I Study (NCT03403725) | Menarini Group | 2017-08-28 |
| Safety Tolerability, and PK of RYI-018 After Repeat Dosing in Subjects With Non-Alcoholic Fatty Liver Disease (NAFLD) (NCT03261739) | Bird Rock Bio, Inc. | 2017-08-28 |
| Radiotherapy to the Prostate and Dominant Intra-Prostatic Lesion (DIL) (NCT03269422) | Memorial Sloan Kettering Cancer Center | 2017-08-28 |
| Stereotactic Body Radiotherapy (SBRT) Followed by Immunotherapy in Liver Cancer (NCT03203304) | University of Chicago | 2017-08-25 |
| A Two Part Study to Assess Safety, PK, PD, and Food Effect of Oral HTL0016878 (NCT03244228) | Nxera Pharma UK Limited | 2017-08-25 |
| Study on the Safety of Neladenoson Bialanate, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Dug Given as a Single Oral Dose in Participants With Liver Impairment and Healthy Participants Matched for Age-, Gender-, and Weight (NCT04322253) | Bayer | 2017-08-24 |
| Impact of Changing the Dosing Regimen on the PK Profile of ODM-203 (NCT03240445) | Orion Corporation, Orion Pharma | 2017-08-24 |
| A Safety, Pharmacokinetic, Single Ascending Dose Study of Tesevatinib in Pediatric Subjects With Autosomal Recessive Polycystic Kidney Disease (ARPKD) (NCT03096080) | Kadmon Corporation, LLC | 2017-08-24 |
| Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers (NCT03190174) | Sarcoma Oncology Research Center, LLC | 2017-08-24 |
| A Study to Evaluate Safety, PK and PD of FDL169 in Cystic Fibrosis Subjects (NCT03093714) | Flatley Discovery Lab LLC | 2017-08-23 |
| Open-label Study of Tofacitinib for Moderate to Severe Skin Involvement in Young Adults With Lupus (NCT03288324) | Children's Hospital Medical Center, Cincinnati | 2017-08-23 |
| Trial of H3B-6545, in Women With Locally Advanced or Metastatic Estrogen Receptor-positive, HER2 Negative Breast Cancer (NCT03250676) | Eisai Inc. | 2017-08-23 |
| Novel PET/CT Imaging Biomarkers of CB-839 in Combination With Panitumumab and Irinotecan in Patients With Metastatic and Refractory RAS Wildtype Colorectal Cancer (NCT03263429) | Vanderbilt-Ingram Cancer Center | 2017-08-23 |
| Sleep and Healthy Aging Research for Depression (SHARE-D) Study (NCT03256760) | Michael Irwin, MD | 2017-08-23 |
| A Study of IMP4297 in Patients With Advanced Solid Tumors (NCT03508011) | Impact Therapeutics, Inc. | 2017-08-23 |
| ERAS in Video-assisted Mediastinal Surgery (NCT03271606) | Shanghai Zhongshan Hospital | 2017-08-23 |
| Paclitaxel/Carboplatin + Galunisertib for Patients With Carcinosarcoma of the Uterus or Ovary (NCT03206177) | University of Oklahoma | 2017-08-23 |
| Study of IMCY-0098 in Patients With Recent Onset Type 1 Diabetes (NCT03272269) | Imcyse SA | 2017-08-23 |
| A Study To Test The Effect Of Apatinib On P450 Enzymes (NCT03245307) | Jiangsu HengRui Medicine Co., Ltd. | 2017-08-22 |
| Evaluating the Safety and Immunogenicity of EnvSeq-1 and CH505 M5 gp120 Envs Adjuvanted With GLA-SE in Healthy, HIV-Uninfected Adults (NCT03220724) | National Institute of Allergy and Infectious Diseases (NIAID) | 2017-08-22 |
| Acute Metabolic Effects of Melatonin Treatment (NCT03204877) | University of Aarhus | 2017-08-22 |
| Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Investigation of GSK3335065 Intravenous (IV) Infusion in Healthy Adults (NCT03245619) | GlaxoSmithKline | 2017-08-22 |
| Pharmacokinetic/Pharmacodynamic Equivalence of MSB11455 in Healthy Subjects (NCT03251248) | Fresenius Kabi SwissBioSim GmbH | 2017-08-22 |
| Safety of TAS-102 in Combination With Temozolomide for Metastatic Pancreatic NETs (NCT02943733) | University of Wisconsin, Madison | 2017-08-22 |
| Safety and Immunogenicity of a Sabin Inactivated Poliovirus Vaccine (NCT04264598) | Jiangsu Province Centers for Disease Control and Prevention | 2017-08-21 |
| Study to Determine and Compare Plasma and Intrapulmonary Concentrations of ETX2514 and Sulbactam in Healthy Subjects (NCT03303924) | Entasis Therapeutics | 2017-08-21 |
| LZM009 to Treat Patients With Advanced Solid Tumors (NCT03286296) | Livzon Pharmaceutical Group Inc. | 2017-08-21 |
| Safety and Efficacy Evaluation of IM19 Cells (NCT03344705) | Beijing Immunochina Medical Science & Technology Co., Ltd. | 2017-08-21 |
| Cardiac Safety Evaluation of P03277 (NCT03657264) | Guerbet | 2017-08-21 |
| Safety, Tolerability and PK of PXL770 in Healthy Male Subjects (NCT03395470) | Poxel SA | 2017-08-21 |
| Pevonedistat and Decitabine in Treating Patients With High Risk Acute Myeloid Leukemia (NCT03009240) | City of Hope Medical Center | 2017-08-21 |
| Safety and Immunogenicity of MSB11455 in Healthy Participants (NCT03251339) | Fresenius Kabi SwissBioSim GmbH | 2017-08-21 |
| A Study to Investigate the Safety, Efficacy and Pharmacokinetic Profile of Multiple Doses of QL-007 in Chronic Hepatitis B Patients (NCT03244085) | Qilu Pharmaceutical Co., Ltd. | 2017-08-20 |
| Anti-CD22 CAR-T Cell Therapy Targeting B Cell Malignancies (NCT03262298) | Affiliated Hospital to Academy of Military Medical Sciences | 2017-08-20 |
| Incidence of Acute Laryngeal Injury Following Endotracheal Intubation (NCT03250975) | Vanderbilt University Medical Center | 2017-08-19 |
| A Study of MGD013 in Patients With Unresectable or Metastatic Neoplasms (NCT03219268) | MacroGenics | 2017-08-18 |
| Food Effect, Oral & Intravenous Pharmacokinetics and Absolute Bioavailability of BAY1834845 Including Drug-drug Interaction With Methotrexate (NCT03244462) | Bayer | 2017-08-18 |
| MANP in Hypertension and Metabolic Syndrome (NCT03781739) | Mayo Clinic | 2017-08-18 |
| Fulvestrant, Palbociclib and Erdafitinib in ER+/HER2-/FGFR-amplified Metastatic Breast Cancer (NCT03238196) | Vanderbilt-Ingram Cancer Center | 2017-08-18 |
| A Phase 1, Randomized, Placebo-and Positive-Controlled Crossover Study to Determine the Effect of Single-Dose GC4419 on QTc Interval in Healthy Volunteers (NCT03164109) | Galera Therapeutics, Inc. | 2017-08-18 |
| Z650 in Advanced Esophageal Squamous Cell Carcinoma With EGFR Over Expression or Gene Amplification (NCT03888092) | Sunshine Lake Pharma Co., Ltd. | 2017-08-18 |
| A Safety Study of PTI-125 in Healthy Volunteers (NCT03784300) | Pain Therapeutics | 2017-08-18 |