| Phase I Study to Assess the Effect of Food on AZD1775 Pharmacokinetics in Patients With Advanced Solid Tumours (NCT03315091) | AstraZeneca | 2017-09-29 |
| A Trial to Investigate the Single Dose Pharmacokinetics of Insulin Degludec/Liraglutide Compared With Insulin Degludec and Liraglutide in Healthy Chinese Subjects (NCT03292185) | Novo Nordisk A/S | 2017-09-29 |
| A Study Comparing the Amounts of 2 Different Forms of Tafamidis (PF06291826), Both With and Without Food, In the Blood (NCT03280173) | Pfizer | 2017-09-29 |
| Targeted Microbiome Transplant in Atopic Dermatitis (NCT03151148) | National Institute of Allergy and Infectious Diseases (NIAID) | 2017-09-28 |
| Clinical Trial to Determine Tolerable Dosis of Vorinostat in Patients With Mild Alzheimer Disease (NCT03056495) | German Center for Neurodegenerative Diseases (DZNE) | 2017-09-28 |
| A Study of the Safety and Tolerability of Inhaled SNSP113 in Healthy Subjects and Subjects With Stable Cystic Fibrosis (NCT03309358) | Synspira, Inc. | 2017-09-28 |
| Evaluation of Effect of Renal Impairment on the PK of Tenofovir Exalidex (NCT03284164) | ContraVir Pharmaceuticals, Inc. | 2017-09-28 |
| A Phase Ib Pharmacodynamic Study of Neoadjuvant Paricalcitol in Resectable Pancreatic Cancer A Phase Ib Pharmacodynamic Study of Neoadjuvant Paricalcitol in Resectable Pancreatic Cancer (NCT03300921) | Abramson Cancer Center at Penn Medicine | 2017-09-28 |
| Safety, PK, and PD Study of IVRs Releasing TFV and LNG (NCT03279120) | CONRAD | 2017-09-28 |
| Study of Pembrolizumab and Cabozantinib in Patients With Metastatic Renal Cell Carcinoma (NCT03149822) | University of Colorado, Denver | 2017-09-28 |
| Hydroxychloroquine for the Treatment of Hidradenitis Suppurativa (NCT03275870) | Elena Gonzalez Brant, MD | 2017-09-28 |
| The Tolerance, Pharmacokinetics of Jaktinib in Healthy Volunteers (NCT03314402) | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 2017-09-28 |
| Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ITI-214 in Parkinson's Disease (NCT03257046) | Intra-Cellular Therapies, Inc. | 2017-09-28 |
| Avelumab and Trabectedin in Treating Patients With Liposarcoma or Leiomyosarcoma That is Metastatic or Cannot Be Removed by Surgery (NCT03074318) | Fred Hutchinson Cancer Center | 2017-09-28 |
| Pembrolizumab and Binimetinib in Treating Patients With Locally Advanced or Metastatic Triple Negative Breast Cancer (NCT03106415) | Mayo Clinic | 2017-09-27 |
| Safety, Pharmacokinetics and Pharmacodynamics Study of Inhaled QBW276 in Patients With Cystic Fibrosis (NCT02566044) | Novartis Pharmaceuticals | 2017-09-27 |
| Study to Evaluate Effects of Probenecid, Rifampin and Verapamil on Bexagliflozin in Healthy Subjects (NCT03296800) | Theracos | 2017-09-27 |
| A Study to Compare the Pharmacokinetics (PK) of GSK2982772 Following Administration of Different Modified Release (MR) Formulations in Capsule and MR Tablet Formulations Relative to an Immediate Release (IR) Tablet Formulation and to Check the PK of MR Formulation in Capsule Following Repeat Doses (NCT03266172) | GlaxoSmithKline | 2017-09-27 |
| The Purpose of the Study is to Compare Two Fixed Dose Combination Tablets of Dapagliflozin/Metformin XR in Healthy Subjects Under Fasting and Fed Conditions (NCT03216278) | AstraZeneca | 2017-09-26 |
| Clinical Study to Test the Safety of CDNF by Brain Infusion in Patients With Parkinson's Disease (NCT03295786) | Herantis Pharma Plc. | 2017-09-26 |
| Pembrolizumab + Idelalisib for Lung Cancer Study (NCT03257722) | Asha Nayak | 2017-09-26 |
| Phase 1 Study of ELX-02 in Healthy Adults (NCT03292302) | Eloxx Pharmaceuticals, Inc. | 2017-09-26 |
| Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia (NCT03214562) | M.D. Anderson Cancer Center | 2017-09-26 |
| A Study to Assess the Effect of Ticlopidine on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine in Healthy Participants (NCT03298906) | Janssen Research & Development, LLC | 2017-09-26 |
| A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG (NCT03330197) | Alaunos Therapeutics | 2017-09-26 |
| Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Sutezolid (NCT03199313) | Global Alliance for TB Drug Development | 2017-09-26 |
| A Study of AG-120 (Ivosidenib) in Subjects With Mild or Moderate Hepatic Impairment or Normal Hepatic Function (NCT03282513) | Agios Pharmaceuticals, Inc. | 2017-09-26 |
| INIA Stress and Chronic Alcohol Interactions: Glucocorticoid Antagonists in Heavy Drinkers (NCT02989662) | Johns Hopkins University | 2017-09-26 |
| Pirfenidone Combined With Standard First-Line Chemotherapy in Advanced-Stage Lung NSCLC (NCT03177291) | H. Lee Moffitt Cancer Center and Research Institute | 2017-09-26 |
| Comparison of the Safety and PK of SYN060 to Humira® in Healthy Adult Subjects (NCT03254810) | Synermore Biologics Co., Ltd. | 2017-09-26 |
| Phase I Study of Pyrimethamine in Healthy Japanese and Caucasian Subjects (NCT03258762) | GlaxoSmithKline | 2017-09-25 |
| Evaluation of Tofacitinib in Early Diffuse Cutaneous Systemic Sclerosis (dcSSc) (NCT03274076) | University of Michigan | 2017-09-25 |
| Phase I Study of TBI-1401(HF10) Plus Chemotherapy in Patients with Unresectable Pancreatic Cancer. (NCT03252808) | Takara Bio Inc. | 2017-09-25 |
| Allogenic Mesenchymal Stem Cells And Physical Therapy for MS Treatment (NCT03326505) | University of Jordan | 2017-09-25 |
| PDR001 in Combination With Bevacizumab and mFOLFOX6 as First Line Therapy in Patients With Metastatic MSS Colorectal Cancer (NCT03176264) | Novartis Pharmaceuticals | 2017-09-25 |
| Hallmarks of Protective Immunity in Sequential Rhinovirus Infections in Humans (NCT02796001) | University of Virginia | 2017-09-25 |
| Does N-Acetylcysteine Decrease Spontaneous Oxidation of Central Neural Dopamine in Parkinson's Disease? (NCT03104725) | National Institute of Neurological Disorders and Stroke (NINDS) | 2017-09-25 |
| Ph I Study of Alvocidib and Cytarabine/Daunorubicin (7+3) in Patients With Newly Diagnosed Acute Myeloid Leukemia (AML). (NCT03298984) | Sumitomo Pharma America, Inc. | 2017-09-25 |
| Focused Ultrasound and Pembrolizumab in Metastatic Breast Cancer (NCT03237572) | Patrick Dillon, MD | 2017-09-25 |
| 4SC-202 in Combination With Pembrolizumab in Patients Primary Refractory/Non-responding to Prior Anti-PD-1 Therapy (NCT03278665) | 4SC AG | 2017-09-25 |
| Novel Compositions for Treating or Preventing Dermal Disorders (NCT03103893) | Drexel University | 2017-09-25 |
| Study of Intratumoral CV8102 in cMEL, cSCC, hnSCC, and ACC (NCT03291002) | CureVac | 2017-09-25 |
| Study of Paclitaxel, Carboplatin, and PF-05212384 in Advanced or Metastatic NSCLC (UF-STO-LUNG-002) (NCT02920450) | University of Florida | 2017-09-25 |
| A Study Designed to Compare the Safety and Pharmacokinetics of Intravenously Administered Superoxide Dismutase Mimetic GC4711 and GC4419 in Healthy Volunteers (NCT03194139) | Galera Therapeutics, Inc. | 2017-09-25 |
| Safety and Efficacy of Expanded Allogeneic AD-MSCs in Patients With Moderate to Severe Psoriasis (NCT03265613) | Guangdong Provincial Hospital of Traditional Chinese Medicine | 2017-09-24 |
| The Effect of Food Intake on the Pharmacokinetic of Single Dose SPH3127 Tablets in Chinese Health Subjects (NCT03249753) | Shanghai Pharmaceuticals Holding Co., Ltd | 2017-09-23 |
| Bioequivalence Study of Ritonavir Versus NORVIR in Healthy Chinese Subjects (NCT03302182) | First Affiliated Hospital of Zhejiang University | 2017-09-23 |
| Positron Emission Tomography (PET) Study in Patients With Alzheimer's Disease (NCT03307993) | H. Lundbeck A/S | 2017-09-22 |
| The Physiologic Effects of Intranasal Oxytocin on Sarcopenic Obesity (NCT03119610) | Sara Espinoza | 2017-09-22 |
| Phase IB Trial of Radium-223 and Niraparib in Patients With Castrate Resistant Prostate Cancer (NiraRad) (NCT03076203) | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 2017-09-22 |
| 18F-Fluoroazomycin Arabinoside PET-CT in Diagnosing Solid Tumors in Patients (NCT03168737) | M.D. Anderson Cancer Center | 2017-09-22 |
| Single and Multiple-Ascending Dose Study of CRN00808 in Healthy Volunteers (NCT03276858) | Crinetics Pharmaceuticals Inc. | 2017-09-22 |
| A Study of BMS-986224 in Healthy Subjects and Heart Failure Patients With Reduced Ejection Fraction (NCT03281122) | Bristol-Myers Squibb | 2017-09-22 |
| Evaluating the Infectivity, Safety, and Immunogenicity of Recombinant Live-Attenuated RSV Vaccines RSV ΔNS2/Δ1313/I1314L or RSV 276 in RSV-Seronegative Infants 6 to 24 Months of Age (NCT03227029) | National Institute of Allergy and Infectious Diseases (NIAID) | 2017-09-22 |
| Safety and Tolerability Study of RO7171009 in Participants With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD) (NCT03295877) | Genentech, Inc. | 2017-09-21 |
| To Assess the Pharmacokinetics, Safety and Tolerability of Abediterol Administered Once Daily for 9 Days, in Patients With Asthma on Inhaled Corticosteroids (NCT03273127) | AstraZeneca | 2017-09-21 |
| A Trial to Assess the Pharmacokinetics, Safety and Tolerability of Semaglutide in Healthy Chinese Subjects (NCT03288740) | Novo Nordisk A/S | 2017-09-21 |
| A Pharmacokinetic Study of Ruxolitinib Phosphate Cream in Pediatric Subjects With Atopic Dermatitis (NCT03257644) | Incyte Corporation | 2017-09-21 |
| Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients (NCT03190941) | National Cancer Institute (NCI) | 2017-09-21 |
| A Phase 1 Study to Evaluate the Effects of Omeprazole and Famotidine on the Absorption of Telotristat Ethyl in Healthy Subjects (NCT03302845) | Lexicon Pharmaceuticals | 2017-09-21 |
| Evaluating the Pharmacokinetics, Safety, and Tolerability of Bedaquiline in Infants, Children, and Adolescents With Multidrug-Resistant Tuberculosis, Living With or Without HIV (NCT02906007) | National Institute of Allergy and Infectious Diseases (NIAID) | 2017-09-21 |
| A Study to Assess the Pharmacokinetics of Enasidenib (CC-90007) in Subjects With Moderate and Severe Hepatic Impairment. (NCT03290443) | Celgene | 2017-09-21 |
| CORT125281 Single Ascending Dose (SAD) and Multiple Ascending Dose (MAD) (NCT03335956) | Corcept Therapeutics | 2017-09-21 |
| Evaluation of the Safety and Pharmacology of EYP001 in HBV Subjects (NCT03272009) | Enyo Pharma | 2017-09-21 |
| Brentuximab Vedotin for Systemic Sclerosis (NCT03222492) | National Institute of Allergy and Infectious Diseases (NIAID) | 2017-09-20 |
| Modification of Extracorporeal Photopheresis in Cutaneous T-cell Lymphoma or Chronic Graft-versus-host Disease (NCT03109353) | St. Olavs Hospital | 2017-09-20 |
| Clinical Bioequivalence Study on Two Methyldopa Tablet 250mg Formulations (NCT03210025) | Bright Future Pharmaceuticals Factory O/B Bright Future Pharmaceutical Laboratories Limited | 2017-09-20 |
| Study of TBI-1301 (NY-ESO-1 T Cell Receptor Gene Transduced Autologous T Lymphocytes) in Patients with Synovial Sarcoma (NCT03250325) | Takara Bio Inc. | 2017-09-20 |
| P-BCMA-101 Tscm CAR-T Cells in the Treatment of Patients With Multiple Myeloma (MM) (NCT03288493) | Poseida Therapeutics, Inc. | 2017-09-20 |
| The Impact of a Combination of Bifidobacterium Longum 35624® and 1714™ Strains in Adults With Irritable Bowel Syndrome (NCT04422327) | PrecisionBiotics Group Ltd. | 2017-09-20 |
| Phase 1/2 Study of Amcenestrant (SAR439859) Single Agent and in Combination With Other Anti-cancer Therapies in Postmenopausal Women With Estrogen Receptor Positive Advanced Breast Cancer (NCT03284957) | Sanofi | 2017-09-20 |
| Study of MK-2118 Administered as Intratumoral Injection as Monotherapy and in Combination With Pembrolizumab (MK-3475) or by Subcutaneous Injection in Combination With Pembrolizumab in the Treatment of Adults With Advanced/Metastatic Solid Tumors or Lymphomas (MK-2118-001) (NCT03249792) | Merck Sharp & Dohme LLC | 2017-09-20 |
| Phase 1 Study of CK-301 (Cosibelimab) as a Single Agent in Subjects With Advanced Cancers (NCT03212404) | Checkpoint Therapeutics, Inc. | 2017-09-20 |
| Phase 1b DV281 With an Anti-PD-1 Inhibitor in NSCLC (NCT03326752) | Dynavax Technologies Corporation | 2017-09-20 |
| A Study Comparing Amounts of 2 Different Forms of Tafamidis (PF-6291826) in the Blood (NCT03266705) | Pfizer | 2017-09-20 |
| Study of a Novel Subcutaneous Depot Formulation of Buprenorphine (NCT03715634) | Indivior Inc. | 2017-09-20 |
| Closed-Loop Glucagon Pump for Treatment of Post-Bariatric Hypoglycemia (NCT03255629) | Joslin Diabetes Center | 2017-09-19 |
| GSK3640254 First Time in Human (FTIH) Study in Healthy Volunteers (NCT03231943) | ViiV Healthcare | 2017-09-19 |
| Dose-Escalation Study of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma (R/R MM) (NCT03275103) | Genentech, Inc. | 2017-09-19 |
| Compare the Analgesic Effect of Different Anesthesia and Postoperative Analgesic Methods in Uniportal VATS Lung Surgery (NCT03311737) | Shanghai Zhongshan Hospital | 2017-09-19 |
| A Study in Healthy Adults to Assess Priming With Antigenically Mismatched Live Attenuated A/H7N3 Influenza Virus Vaccine Followed by Inactivated A/H7N9 Influenza Virus Vaccine (NCT03581903) | National Institute of Allergy and Infectious Diseases (NIAID) | 2017-09-19 |
| Study to Assess the Safety, Tolerability, and Preliminary Efficacy of B244 in Healthy Volunteers and Subjects With Seasonal Allergic Rhinitis (NCT03290248) | AOBiome LLC | 2017-09-19 |
| A First-in-Human Study of CAN04 in Patients With Solid Malignant Tumors (NCT03267316) | Cantargia AB | 2017-09-19 |
| Effects of Aging on Primary and Secondary Vaccine Responses (NCT03312699) | Stanford University | 2017-09-19 |
| PK/PD Clinical Trial of YYD601 in Healthy Adult Male (NCT03558477) | Yooyoung Pharmaceutical Co., Ltd. | 2017-09-19 |
| IMA970A Plus CV8102 in Very Early, Early and Intermediate Stage Hepatocellular Carcinoma Patients (NCT03203005) | National Cancer Institute, Naples | 2017-09-18 |
| This is a Study to Evaluate the Safety and Tolerability of the Study Drug ABL001, and to Determine the Maximum Tolerated Dose and/or Recommended Phase 2 Study Dose of ABL001 (NCT03292783) | ABL Bio, Inc. | 2017-09-18 |
| Phase 1 Study to Investigate Effect of Rifampin and Itraconazole on the Pharmacokinetics of BGB-3111 in Healthy Subjects (NCT03301181) | BeiGene | 2017-09-18 |
| A Phase 1b Open-Label Study Investigating the Safety and Pharmacokinetics of Administration of Subcutaneous Blinatumomab for the Treatment of Relapsed/Refractory Indolent Non-Hodgkin's Lymphoma (NCT02961881) | Amgen | 2017-09-18 |
| Treatment of Restless Leg Syndrome (RLS) Augmentation With Ecopipam, a D1 Specific Antagonist (NCT03218969) | William Ondo, MD | 2017-09-18 |
| The Pharmacokinetics and Safety of Single-dose and Parallel Comparisons in Patients With NSCLC Treated With JS001 (NCT03301688) | Shanghai Junshi Bioscience Co., Ltd. | 2017-09-18 |
| A Study to Investigate Biomarker Effects of Pre-Surgical Treatment With DNA Damage Repair (DDR) Agents in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC). (NCT03022409) | AstraZeneca | 2017-09-18 |
| Evaluation of the Safety and Immunogenicity of a Recombinant Trivalent Nanoparticle Influenza Vaccine With Matrix M-1 Adjuvant (NanoFlu) (NCT03293498) | Novavax | 2017-09-18 |
| A Study to Determine the Abuse Potential of Tozadenant Relative to D-Amphetamine and Placebo When Administered Orally in Healthy, Non-Dependent, Recreational Polydrug Users (NCT03200080) | Biotie Therapies Inc. | 2017-09-18 |
| PIPAC Nab-pac for Stomach, Pancreas, Breast and Ovarian Cancer (NCT03304210) | University Hospital, Ghent | 2017-09-16 |
| Gene Therapy for Beta-Thalassemia Major Using Autologous Hematopoietic Stem Cell Genetically Modified (NCT03276455) | Nanfang Hospital, Southern Medical University | 2017-09-15 |
| First-in-Human Trial of Single Ascending Dose, Multiple Ascending Dose and Malaria Challenge Model in Healthy Participants (NCT03261401) | Merck KGaA, Darmstadt, Germany | 2017-09-15 |
| Safety and Immunogenicity of High-Dose Quadrivalent Influenza Vaccine in Patients ≥65 Years (NCT03233217) | Sanofi Pasteur, a Sanofi Company | 2017-09-15 |
| CAR T Cell Immunotherapy for Pancreatic Cancer (NCT03323944) | University of Pennsylvania | 2017-09-15 |
| VSV-hIFNbeta-NIS With or Without Ruxolitinib Phosphate in Treating Stage IV or Recurrent Endometrial Cancer (NCT03120624) | Mayo Clinic | 2017-09-15 |