| OX40, Venetoclax, Avelumab, Glasdegib, Gemtuzumab Ozogamicin, and Azacitidine in Relapsed or Refractory Acute Myeloid Leukemia (NCT03390296) | M.D. Anderson Cancer Center | 2017-12-27 |
| Safety and Efficacy of MAGE-A3/A6 T Cell Receptor Engineered T Cells (KITE-718) in HLA-DPB1*04:01 Positive Adults With Advanced Cancers (NCT03139370) | Kite, A Gilead Company | 2017-12-27 |
| Study Evaluating Safety, Tolerability and Pharmacokinetics (PK) of Tarlatamab in Adults With Small Cell Lung Cancer (SCLC) (NCT03319940) | Amgen | 2017-12-26 |
| Phase 1 Study to Evaluate the Effect of DS-8201a on the QT/QTc Interval and Pharmacokinetics in HER2-Expressing Breast Cancer (NCT03366428) | Daiichi Sankyo Co., Ltd. | 2017-12-26 |
| A New Drug Used for Advanced Cancer (NCT03447145) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2017-12-26 |
| A Phase I Study of YY-20394 in Patients With B Cell Hematologic Malignancies (NCT03757000) | Shanghai YingLi Pharmaceutical Co. Ltd. | 2017-12-25 |
| Anti-CD19 CAR T Cells in Pediatric Patients Affected by Relapsed/Refractory CD19+ ALL and NHL (NCT03373071) | Bambino Gesù Hospital and Research Institute | 2017-12-23 |
| A Study to Assess LY01005 Versus Goserelin Comparator (ZOLADEX®) in Patients With Prostate Cancer (NCT03450109) | Luye Pharma Group Ltd. | 2017-12-22 |
| A Study of Multiple Immunotherapy-Based Treatment Combinations in Hormone Receptor (HR)-Positive Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast Cancer (NCT03280563) | Hoffmann-La Roche | 2017-12-22 |
| Clinical Trial to Investigate the Safety, Tolerability and Pharmacokinetics and Pharmacodynamics of JP-1366 Oral Administration in Healthy Male Subjects (NCT03383042) | Jeil Pharmaceutical Co., Ltd. | 2017-12-22 |
| A Study of RG-012 in Subjects With Alport Syndrome (NCT03373786) | Genzyme, a Sanofi Company | 2017-12-22 |
| Clinical Trial to Investigate the Efficacy and Safety of DWJ1351 (NCT03753477) | Daewoong Pharmaceutical Co. LTD. | 2017-12-22 |
| A Study to Assess the Nicotine Pharmacokinetics, Tolerability and Safety With a New Oral Nicotine Replacement Product in Healthy Japanese Smokers (NCT03398876) | Janssen Pharmaceutical K.K. | 2017-12-22 |
| A Study to Evaluate Apatinib (Also Known as Rivoceranib) Plus Nivolumab in Participants With Unresectable or Metastatic Cancer (NCT03396211) | Elevar Therapeutics | 2017-12-22 |
| Breast Cancer Study of Preoperative Pembrolizumab + Radiation (NCT03366844) | Stephen Shiao | 2017-12-22 |
| A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-63733657 in Healthy Subjects and Subjects With Alzheimer's Disease (NCT03375697) | Janssen Research & Development, LLC | 2017-12-22 |
| Clinical Trial of Metastasis Inhibitor NP-G2-044 in Patients With Advanced or Metastatic Treatment-Refractory Solid Tumor Malignancies (NCT03199586) | Novita Pharmaceuticals, Inc. | 2017-12-21 |
| Safety And Efficacy Study Of Avelumab Plus Chemotherapy With Or Without Other Anti-Cancer Immunotherapy Agents In Patients With Advanced Malignancies (NCT03317496) | Pfizer | 2017-12-21 |
| Pegzilarginase and Pembrolizumab for Extensive Disease Small Cell Lung Cancer (NCT03371979) | Aeglea Biotherapeutics | 2017-12-21 |
| A Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors (NCT03289962) | Genentech, Inc. | 2017-12-21 |
| Study to Assess the Safety, Tolerability, and Pharmacokinetics of E2082 in Healthy Male Subjects (NCT03402178) | Eisai Co., Ltd. | 2017-12-21 |
| Mesenchymal Stromal Cells for Haplo Hematopoietic Cell Transplantation for Sickle Cell Disease (NCT03298399) | Emory University | 2017-12-21 |
| A Study in Healthy Participants Evaluating the Absorption of a BMS-986205 Tablet Into the Bloodstream Compared to a Reference Tablet (NCT03378310) | Bristol-Myers Squibb | 2017-12-21 |
| Augmentation of the Graft vs. Leukemia Effect Via Checkpoint Blockade With Pembrolizumab (NCT03286114) | University of Michigan Rogel Cancer Center | 2017-12-21 |
| A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics in Healthy Adult Male Participants (NCT03390647) | EA Pharma Co., Ltd. | 2017-12-21 |
| Transposon-manipulated Allogeneic CARCIK-CD19 Cells in Pediatric and Adult Patients With r/r ALL Post HSCT (NCT03389035) | Fondazione Matilde Tettamanti Menotti De Marchi Onlus | 2017-12-20 |
| FLOTOR Pilot Study (NCT03292757) | Oxford University Hospitals NHS Trust | 2017-12-20 |
| Evaluating of the Safety, Pharmacokinetics and Pharmacodynamics of QL1205 and Lucentis® in Patients With Wet AMD (NCT03312283) | Qilu Pharmaceutical Co., Ltd. | 2017-12-20 |
| A Clinical Study to Investigate if SAR425899 Binds to the Liver and Pancreas in Overweight to Obese Type 2 Diabetes Mellitus Patients (NCT03350191) | Sanofi | 2017-12-20 |
| Cetuximab & Nivolumab in Patients With Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma (NCT03370276) | H. Lee Moffitt Cancer Center and Research Institute | 2017-12-20 |
| HDR Brachytherapy, EBRT and STAD for the Treatment of Prostate Cancer (NCT03553602) | Loyola University | 2017-12-20 |
| Bioequivalence (BE) Study Comparing Azithromycin 250 mg Tablet Manufactured in China and in the United States (NCT03353480) | Pfizer | 2017-12-20 |
| Stereotactic Body Radiation Therapy and Avelumab Immunotherapy for Treatment of Malignant Mesothelioma (NCT03399552) | Memorial Sloan Kettering Cancer Center | 2017-12-20 |
| Obinutuzumab, High Dose Methylprednisolone (HDMP), and Lenalidomide for the Treatment of Patients With Richter's Syndrome (NCT03113695) | University of California, San Diego | 2017-12-20 |
| Phase 1/2 Study of Combination Immunotherapy and Messenger Ribonucleic Acid (mRNA) Vaccine in Subjects With NSCLC (NCT03164772) | Ludwig Institute for Cancer Research | 2017-12-20 |
| A Safety and Efficacy Trial of JCAR017 Combinations in Subjects With Relapsed/Refractory B-cell Malignancies (NCT03310619) | Celgene | 2017-12-20 |
| Anastrozole, Palbociclib, Trastuzumab and Pertuzumab in HR-positive, HER2-positive Metastatic Breast (NCT03304080) | Icahn School of Medicine at Mount Sinai | 2017-12-20 |
| Pharmacokinetics and Safety of Intravenous Posaconazole (MK-5592) in Chinese Participants at High Risk for Invasive Fungal Infections (MK-5592-120) (NCT03336502) | Merck Sharp & Dohme LLC | 2017-12-20 |
| Single-Dose Pharmacokinetics of MK-3866 in Participants With Hepatic Impairment (MK-3866-006) (NCT03295266) | Merck Sharp & Dohme LLC | 2017-12-19 |
| Mass Balance Study With MT-8554 (NCT03381404) | Tanabe Pharma America, Inc. | 2017-12-19 |
| The Clinical Trial to Evaluate the Pharmacokinetics, Safety and Tolerability of ZL-2306 (Niraparib) in Patients With Ovarian Cancer (NCT03551171) | Zai Lab (Shanghai) Co., Ltd. | 2017-12-19 |
| Study of Durvalumab and Guadecitabine in Advanced Kidney Cancer (NCT03308396) | Ajjai Alva, MD | 2017-12-19 |
| A Study of Tirzepatide (LY3298176) in Healthy Participants (NCT03375463) | Eli Lilly and Company | 2017-12-19 |
| Study of PF-05221304 in Subjects With Varying Degrees of Hepatic Impairment (NCT03309202) | Pfizer | 2017-12-19 |
| Dosimetry Study of Betalutin for Treatment of Relapsed Non-Hodgkin Lymphoma (LYMRIT-37-02) (NCT02657447) | Nordic Nanovector | 2017-12-19 |
| Efficacy of Fish Oil or Olive Oil Supplementation on the Health Effects of Ozone Exposure in Healthy Young Subjects (NCT03395119) | University of North Carolina, Chapel Hill | 2017-12-18 |
| A Study of Zalifrelimab and Balstilimab for Treatment of Participants With Metastatic or Locally Advanced Solid Tumors, and Expansion Into Select Solid Tumors (Cervical) (NCT03495882) | Agenus Inc. | 2017-12-18 |
| A Study of the Pharmacokinetics, Safety and Tolerability of Single Doses of VR647 Inhalation Suspension Administered Using the VR647 Inhalation System in Children With Wheezing, Reactive Airway Disease or Mild Asthma (NCT03421730) | Vectura Limited | 2017-12-18 |
| An Phase 1 Study to Evaluate the Pharmacokinetic (PK) Profile of FDL169 New Formulations in Healthy Subjects (NCT03424252) | Flatley Discovery Lab LLC | 2017-12-18 |
| A 3-Way Crossover Study to Evaluate the Pharmacokinetics in Participants After Dosing With Pegilodecakin (LY3500518) (NCT03381547) | Eli Lilly and Company | 2017-12-18 |
| Phase 1 Study for Safety and Tolerability of IL-1-Ra Topically Administered to Eyes of Healthy Adult Subjects (NCT03383276) | Beijing Tongren Hospital | 2017-12-18 |
| Study of Testosterone and rHGH in FSHD (NCT03123913) | University of Rochester | 2017-12-18 |
| A Study of Pembrolizumab And Platinum With Radiotherapy in Cervix Cancer (NCT03144466) | Royal Marsden NHS Foundation Trust | 2017-12-18 |
| Bioequivalence Study Between a 4-mg Dose of Fine Granules of Perampanel and a 4-mg Tablet of Perampanel in Healthy Japanese Subjects (NCT03399734) | Eisai Co., Ltd. | 2017-12-18 |
| Study of Single Agent CJM112, and PDR001 in Combination With LCL161 or CJM112 in Patients With Multiple Myeloma (NCT03111992) | Novartis Pharmaceuticals | 2017-12-18 |
| Study to Investigate the Pharmacokinetic Profile (NCT03286829) | Saniona | 2017-12-18 |
| A Bronchoprovocation Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CSJ117 in Adult Subjects With Mild Atopic Asthma (NCT03138811) | Novartis Pharmaceuticals | 2017-12-18 |
| Bioavailability and Bioequivalence of Ezetimibe Tablets in Healthy Subjects (NCT05681247) | The Affiliated Hospital of Qingdao University | 2017-12-17 |
| A Phase I Study of SCC244 in Patients with Advanced MET Alterations Solid Tumors (NCT03457532) | Haihe Biopharma Co., Ltd. | 2017-12-16 |
| Image Guided Surgery for Margin Assessment of Head and Neck Cancer Using Cetuximab-IRDye800CW cONjugate (NCT03134846) | University Medical Center Groningen | 2017-12-16 |
| A Study of the Systemic Absorption of MOB015B (NCT03244280) | Moberg Pharma AB | 2017-12-16 |
| Dose Escalation Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma (NCT03399799) | Janssen Research & Development, LLC | 2017-12-16 |
| Anti-Shiga Toxin Hyperimmune Equine Immunoglobulin F(ab')2 Fragment (INM004) in Healthy Volunteers (NCT03388216) | Inmunova S.A. | 2017-12-16 |
| Trial of Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) (NCT03410030) | HonorHealth Research Institute | 2017-12-15 |
| Phase Ib Study of Chiauranib in Patients With Ovarian Cancer (NCT03166891) | Chipscreen Biosciences, Ltd. | 2017-12-15 |
| Multi-Dose Study of SHR-1314 in Subjects With Moderate-to-severe Plaque Psoriasis (NCT03463187) | Jiangsu HengRui Medicine Co., Ltd. | 2017-12-15 |
| Drug Interaction Study of Fimasartan/Amlodipine/Hydrochlorothiazide in Healthy Male Subjects (NCT03390465) | Boryung Pharmaceutical Co., Ltd | 2017-12-15 |
| VX15/2503 and Immunotherapy in Resectable Pancreatic and Colorectal Cancer (NCT03373188) | Emory University | 2017-12-15 |
| SGI-110 Plus Durvalumab/Tremelimumab in SCLC (NCT03085849) | Catherine Shu | 2017-12-15 |
| Mesenchymal Stem Cells in Early Rheumatoid Arthritis (NCT03186417) | MetroHealth Medical Center | 2017-12-15 |
| Safety, Tolerability, and Efficacy Study of CLL442 in Patients With Cutaneous Squamous Cell Carcinoma in Situ (SCCis) (NCT03333694) | Novartis Pharmaceuticals | 2017-12-15 |
| Drug-drug Interaction Study to Evaluate the Effect of ISIS 681257 on Warfarin (NCT03426033) | Akcea Therapeutics | 2017-12-15 |
| Arsenic Trioxide With Cyclophosphamide in Patients With Relapsed/Refractory Acute Myeloid Leukemia (NCT03318016) | University of Colorado, Denver | 2017-12-15 |
| A Phase 1/2a Dose-Finding Study of PT-112 in Patients With Relapsed or Refractory Multiple Myeloma (NCT03288480) | Promontory Therapeutics Inc. | 2017-12-15 |
| Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma (NCT03250299) | Basilea Pharmaceutica | 2017-12-15 |
| Study to Investigate the Safety and Efficacy of GC3107 (BCG Vaccine) in Healthy Adults (NCT03363178) | Green Cross Corporation | 2017-12-14 |
| A Study of DSP-7888 Dosing Emulsion in Combination With Immune Checkpoint Inhibitors in Adult Patients With Advanced Solid Tumors (NCT03311334) | Sumitomo Pharma America, Inc. | 2017-12-14 |
| ORIOn-E: A Study Evaluating CPI-1205 in Patients With Advanced Solid Tumors (NCT03525795) | Constellation Pharmaceuticals | 2017-12-14 |
| Study of Aolanti Weikang Tablets in Healthy Volunteers (NCT03358485) | Jiangxi Qingfeng Pharmaceutical Co. Ltd. | 2017-12-14 |
| Long-term Immunogenicity of the HIV gp120-NefTat/AS01B Vaccine (GSK SB732461) (NCT03368053) | GlaxoSmithKline | 2017-12-14 |
| Effects of Salvinorin A on Brain Function (NCT03418714) | Johns Hopkins University | 2017-12-14 |
| Study of Intrathecal Administration of Onasemnogene Abeparvovec-xioi for Spinal Muscular Atrophy (NCT03381729) | Novartis Gene Therapies | 2017-12-14 |
| A Study to Evaluate Pharmacokinetic (PK), Safety and Tolerability of GSK2894512 in Healthy Adult Subjects (NCT03201978) | GlaxoSmithKline | 2017-12-14 |
| Study of the Metabolism and Excretion of Zidebactam (WCK 5107) Following a Single Intravenous Infusion. (NCT07247942) | Wockhardt | 2017-12-13 |
| DAW1033D in Obstructive Sleep Apnea (NCT03383887) | Brigham and Women's Hospital | 2017-12-13 |
| BE Study of the Combinations of Gemigliptin/Metformin HCl Extended Release 50/1000mg(25/500mg x 2 Tablets) in Comparison to Each Component Administered Alone (NCT03355014) | LG Chem | 2017-12-13 |
| Capecitabine 7/7 Schedule With Neratinib in Patients With Metastatic HER2-Positive Breast Cancer (NCT03377387) | Memorial Sloan Kettering Cancer Center | 2017-12-13 |
| Comparison of Exposure and Activity of SAR341402 Mix 70/30 to NovoLog Mix 70/30, NovoMix 30 and SAR341402 Rapid-acting Solution in Patients With Type 1 Diabetes Mellitus (NCT03916601) | Sanofi | 2017-12-13 |
| Treatment of MEDITOXIN® in Female Patients With Idiopathic Overactive Bladder (NCT03371342) | Medy-Tox | 2017-12-13 |
| Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 986 Administered Orally to Healthy Volunteers and Participants With Severely Impaired Renal Function (NCT03318809) | Amgen | 2017-12-12 |
| PVX-410 Vaccine Plus Pembrolizumab in HLA-A2+ Metastatic Triple Negative Breast Cancer (NCT03362060) | Massachusetts General Hospital | 2017-12-12 |
| Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects (NCT03340597) | F2G Ltd | 2017-12-12 |
| First-in-Human Study of XMT-1536 in Cancers Likely to Express NaPi2b (NCT03319628) | Mersana Therapeutics | 2017-12-12 |
| First-in-Human Dose Escalation Study of XMT-1536 in Cancers Likely to Express NaPi2b (NCT06517433) | Mersana Therapeutics | 2017-12-12 |
| Peptide Vaccination Against PD-L1 and PD-L2 in Relapsed Follicular Lymphoma (NCT03381768) | Lars Møller Pedersen | 2017-12-12 |
| Mesenchymal Stem Cells Therapy in Patients With Recent Intracerebral Hemorrhage (NCT03371329) | Mayo Clinic | 2017-12-12 |
| The Food Effect on the Pharmacokinetics of NVP-1402 (NCT03340480) | NVP Healthcare | 2017-12-12 |
| A 4-Day Study to Evaluate the Photoxicity of Diacerein 1% Topical Ointment in Healthy Volunteers (NCT03473184) | Castle Creek Pharmaceuticals, LLC | 2017-12-12 |
| To Evaluate the Therapeutic Equivalence and Safety in Treatment of Moderate Facial Rosacea (NCT03689010) | Sun Pharmaceutical Industries, Inc. | 2017-12-12 |
| Phase I Trial of Defactinib and VS-6766. (NCT03875820) | Institute of Cancer Research, United Kingdom | 2017-12-12 |