| EVR and EPO for Liver Transplant Tolerance (NCT06832189) | National Institute of Allergy and Infectious Diseases (NIAID) | 2026-01-21 |
| Phase Ia Clinical Trial of Group ACYW135X Meningococcal Conjugate Vaccine (NCT07374510) | Sinovac Life Sciences Co., Ltd. | 2026-01-21 |
| Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory Sarcomas (NCT07222735) | St. Jude Children's Research Hospital | 2026-01-21 |
| A Study of AP601 in Patients With Locally Unresectable Advanced or Metastatic Solid Tumors (NCT07165067) | AP Biosciences Inc. | 2026-01-21 |
| Asciminib Maintenance Therapy Following alloHCT or CAR T to Prevent Relapse in Adults With Ph+ALL (NCT07250087) | H. Lee Moffitt Cancer Center and Research Institute | 2026-01-21 |
| Safety and Efficacy of FAP iCDC in Acute Myocardial Infarction With Cardiogenic Shock (NCT07380659) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2026-01-20 |
| A Study to Evaluate the Safety and Drug Levels of ASP5541 in Chinese Participants With Prostate Cancer (NCT07339267) | Astellas Pharma Global Development, Inc. | 2026-01-20 |
| Iadademstat + SBRT With Atezo in ES-SCLC (NCT07113691) | Yale University | 2026-01-20 |
| A Phase I Study to Evaluate the Safety and Preliminary Efficacy of [225Ac]Ac-DOTATATE Injection Combined With Tislelizumab in the Maintenance Treatment Period for Patients of Extensive-stage Small Cell Lung Cancer (ES-SCLC) With Somatostatin Receptors (SSTR)+ as First-line Treatment (NCT07413042) | Peking University Cancer Hospital & Institute | 2026-01-20 |
| Lenacapavir Intensification to Disrupt HIV Reservoirs in Virologically Suppressed People With HIV Receiving Antiretroviral Therapy (NCT06819176) | National Institute of Allergy and Infectious Diseases (NIAID) | 2026-01-20 |
| A Study of JNJ-95566692 in Participants With Non-Hodgkin Lymphoid Malignancies (NCT07308132) | Janssen Research & Development, LLC | 2026-01-20 |
| EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors (NCT07262619) | Eikon Therapeutics | 2026-01-20 |
| CARE-Melanoma Trial (NCT07320222) | McMaster University | 2026-01-20 |
| NK-cell Therapy Combined With PD-1 Antibody and Platinum-Based Chemotherapy as Neoadjuvant Therapy in Resectable NSCLC (NCT07318636) | The First Affiliated Hospital of Guangzhou Medical University | 2026-01-20 |
| A Study of DB-1324 in Advanced/Metastatic Gastrointestinal Tumors (NCT07263594) | DualityBio Inc. | 2026-01-20 |
| To Evaluate the Adhesion of TK-254RX on Healthy Participants (NCT07307794) | Teikoku Seiyaku Co., Ltd. | 2026-01-19 |
| Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult Participants (NCT07230834) | Regeneron Pharmaceuticals | 2026-01-19 |
| 5G-PEARL: Paxalisib in Malignant Brain Tumours (NCT07391215) | Institute of Cancer Research, United Kingdom | 2026-01-19 |
| A Study to Investigate Andexanet Dosing and the Interaction Between Andexanet and Subsequent Enoxaparin in Healthy Participants (NCT07312851) | AstraZeneca | 2026-01-19 |
| First in Human Study of SIM0610 in Solid Tumors (NCT07348211) | Jiangsu Simcere Pharmaceutical Co., Ltd. | 2026-01-19 |
| A Clinical Study of HX111 in Patients With Advanced Solid Tumor and Lymphoma (NCT07333469) | Hanx Biopharmaceuticals (Wuhan) Co., Ltd. | 2026-01-19 |
| A Study of MHB048C in Patients With Advanced Solid Tumors (NCT07192120) | Minghui Pharmaceutical (Hangzhou) Ltd | 2026-01-16 |
| Comparing the Extent to Which Two Evolocumab Drug Products Are Made Available in the Body After a Single Subcutaneous Dose (NCT07422285) | Amgen | 2026-01-16 |
| A First-in-Human Trial of DS3790a in Participants With Hematological Malignancies (NCT07220616) | Daiichi Sankyo | 2026-01-16 |
| Genetically Engineered Cells (FH-FOLR1 ST CAR T Cells) for the Treatment of Advanced Refractory or Recurrent/Progressive Osteosarcoma, FIERCe Trial (NCT07227571) | Fred Hutchinson Cancer Center | 2026-01-16 |
| Phase Ib/II Clinical Study of QLS1304 Combined With Endocrine Therapy in the Treatment of ER+/HER2- Breast Cancer Patients (NCT07235176) | Qilu Pharmaceutical Co., Ltd. | 2026-01-16 |
| A Study on Yiyang Huoluo Decoction in the Treatment of Coronary Heart Disease (NCT07493603) | Xia Liang | 2026-01-16 |
| Two Part Study of Nenocorilant Combined With Nivolumab in Patients With Advanced Solid Malignancies (NCT07276373) | Corcept Therapeutics | 2026-01-16 |
| A Study of Revumenib and Mezigdomide in People With Leukemia (NCT07356154) | Memorial Sloan Kettering Cancer Center | 2026-01-16 |
| Study of Naive HBI0101 CAR-T Therapy in Relapsed/Refractory Multiple Myeloma (NCT07333430) | Hadassah Medical Organization | 2026-01-15 |
| A Phase 1b Study of BHV-7000 in Participants With Inherited Erythromelalgia (NCT07262268) | Biohaven Therapeutics Ltd. | 2026-01-15 |
| Efficacy and Safety of Microtransplantation for Advanced and Relapsed Solid Tumors (NCT07356856) | The Affiliated Hospital of the Chinese Academy of Military Medical Sciences | 2026-01-15 |
| A Brain Imaging Study to Assess the Binding of MSP-2020 to Serotonin 5-HT2A Receptors in Healthy Male Adults (NCT07329621) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2026-01-15 |
| A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer (NCT07321106) | Cartography Biosciences | 2026-01-15 |
| A Phase 1 Study of a Tablet Form of ABBV-722 Taken With and Without Food in Healthy Adult Participants (NCT07361367) | AbbVie | 2026-01-15 |
| A Single and Multiple Ascending Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SYH2072 Tablets (NCT07647783) | InnovStone Therapeutics Limited | 2026-01-15 |
| Evaluation of Stem Cell Exosomes Versus Platelet-Rich Fibrin in Tooth Extraction Socket Healing (NCT07508033) | Al Salam University | 2026-01-15 |
| Phase Ib/IIa Clinical Trial of SIBP-A16 Injection in Premature Infants and Full-term Infants (NCT07363837) | Shanghai Institute Of Biological Products | 2026-01-15 |
| Parathyroid Allotransplant for Treatment of Hypoparathyroidism (NCT06961071) | Peter Stock | 2026-01-15 |
| Deep Brain Stimulation of the Deep Cerebellar Nuclei for Refractory Tremor (NCT07049003) | The Cleveland Clinic | 2026-01-15 |
| A Study of LY4515100 in Healthy Participants (NCT07339722) | Eli Lilly and Company | 2026-01-15 |
| POCUS-Guided Esmolol in Septic Shock: A Pilot RCT (NCT07313605) | John Basmaji | 2026-01-15 |
| Fluorescence Imaging of Adalimumab-680LT and Risankizumab-800CW in Inflammatory Bowel Disease (NCT07258641) | University Medical Center Groningen | 2026-01-15 |
| Dual-Site Transcranial Magnetic Stimulation of the Supplementary Motor Area and Cerebellum for the Treatment of Essential Tremor. (NCT07344194) | São Paulo State University | 2026-01-15 |
| A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC) (NCT07195682) | Bristol-Myers Squibb | 2026-01-15 |
| Clinical Study of XP-006 mRNA Vaccine for R/R B-NHL (NCT07334574) | Ruijin Hospital | 2026-01-15 |
| Senolytics for Secondary Progressive MS (NCT07270120) | Ohio State University | 2026-01-15 |
| Home-based Vision Therapy (NCT06886737) | VA Office of Research and Development | 2026-01-14 |
| A Study of an IDH1m Inhibitor in Participants With IDH1-Mutated Malignancies and Hepatic or Renal Impairment (NCT07006688) | Servier Bio-Innovation LLC | 2026-01-14 |
| PET Imaging With [18F]Fluselenamyl in People With Cardiac Amyloidosis (NCT07771621) | Washington University School of Medicine | 2026-01-14 |
| A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer (NCT07319871) | Janssen Research & Development, LLC | 2026-01-14 |
| A First-in-human Trial of GRT7041 in Healthy Participants (NCT07289776) | Grünenthal GmbH | 2026-01-14 |
| A Study to Evaluate the Effect of AZD6793 on the Pharmacokinetics and Pharmacodynamics of Metformin in Participants With Type 2 Diabetes Mellitus (NCT07433062) | AstraZeneca | 2026-01-14 |
| Anti-CD19/20/22 Chimeric Antigen Receptor T Cells (TriCAR19.20.22 T Cells) for the Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma, Acute Lymphoblastic Leukemia, and Chronic Lymphocytic Leukemia (NCT07166419) | Ohio State University Comprehensive Cancer Center | 2026-01-14 |
| A Study to Evaluate the Effect of Fasting Duration and Tirzepatide Withholding on the Amount of Food and Fluid in the Stomach in Participants With Type 2 Diabetes Mellitus and Participants With Overweight or Obesity Without Type 2 Diabetes Mellitus (NCT07299084) | Eli Lilly and Company | 2026-01-14 |
| FIH Study to Evaluate Safety, Tolerability, PK, PD & Preliminary Efficacy of AT03-65 With Advanced Solid Tumors (NCT06809114) | Axcynsis Therapeutics Pte Ltd | 2026-01-14 |
| Evaluation of the Safety, Tolerability and Pharmacokinetics of HY8931 in Healthy Adult Participants (NCT07281703) | Newsoara Biopharma Co., Ltd. | 2026-01-14 |
| Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune Disorders (NCT07089121) | Cartesian Therapeutics | 2026-01-14 |
| A Study of HRS-1301 Tablets in Healthy Subjects and Those With Impaired Kidney Function (NCT07322016) | Shandong Suncadia Medicine Co., Ltd. | 2026-01-13 |
| A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-0587 as a Monotherapy and in Combination With Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive and Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (NCT07214662) | Genentech, Inc. | 2026-01-13 |
| A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002) (NCT07300267) | Merck Sharp & Dohme LLC | 2026-01-13 |
| Analgesic Efficacy of Pre-Operative Dose of Palmitoylethanolamide in Patients Undergoing Total Knee Arthroplasty (NCT07330765) | Abdelrahman Gaber Sayed Elkhateeb | 2026-01-13 |
| A Phase I Trial of A-CAR032 in Participants With mCRPC (NCT07344311) | Shanghai AbelZeta Ltd. | 2026-01-13 |
| TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC) (NCT07190300) | Novartis Pharmaceuticals | 2026-01-13 |
| Investigation of Individualised Antisense Oligonucleotides (ASOs) in People With Unique Genetic Variants Causing Severely Debilitating, Life Threatening (SDLT) Central Nervous System (CNS) Conditions (NCT07410143) | EveryONE Medicines Inc. | 2026-01-13 |
| First-in-human Study of 7MW4911 in GI Cancer (NCT07216560) | Mabwell (Shanghai) Bioscience Co., Ltd. | 2026-01-13 |
| A Phase I Study of JLM019 Injection (NCT07623850) | Jecho Biopharmaceuticals Co., Ltd. | 2026-01-13 |
| Safety and Efficacy of AAV9. hMCOLN1co For Patients With Mucolipidosis Type IV (NCT07398872) | The Children's Hospital of Zhejiang University School of Medicine | 2026-01-13 |
| A Study of SYNT-101 to Test Safety, Tolerability and Pharmacodynamics of SYNT-101 in Healthy and Overweight Adults (NCT07307274) | Syntis Bio | 2026-01-13 |
| Phase 1b Safety Study of IMSB301 in Type 1 Interferonopathies (NCT07364513) | ImmuneSensor Therapeutics Inc. | 2026-01-12 |
| This Clinical Trial is Designed to Evaluate the Safety, Tolerability, Feasibility and Preliminary Efficacy of NouvNeu001 (Human Dopaminergic Progenitor Cells Injection) in Patients With Parkinson's Disease. (NCT07102342) | iRegene Therapeutics Co., Ltd. | 2026-01-12 |
| A Clinical Study to Evaluate the Safety of VIB305 in Patients With Advanced Solid Tumors (NCT07222969) | Vibrant Sciences Limited | 2026-01-12 |
| A Study of LY4064809 in Healthy Adult Participants (NCT07339735) | Eli Lilly and Company | 2026-01-12 |
| Study of EPI-001 in Patients With Androgenetic Alopecia (NCT07618195) | Epibiotech | 2026-01-12 |
| A Phase I, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single Ascending Doses of SIM0811 Injection in Healthy Chinese Adult Participants (NCT07345364) | Jiangsu Simcere Pharmaceutical Co., Ltd. | 2026-01-12 |
| A First-in-Human Single and Multiple Ascending Dose Study of MT-701 (NCT07396909) | Mirador Therapeutics, Inc. | 2026-01-12 |
| A Single Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of SYH2085 (NCT07412353) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2026-01-12 |
| Effects of Caffeine Ingestion on Morning Cognitive and 4-km Time Trial Performance in Males (NCT07469852) | Liverpool John Moores University | 2026-01-12 |
| A Clinical Trial to Evaluate EDV Nanocell Therapy With Gemcitabine and Nab-paclitaxel in Pancreatic Cancer (NCT07049055) | Engeneic Pty Limited | 2026-01-12 |
| A Study to Evaluate the Safety of Increasing Doses of DF5112 in Healthy Adults (NCT07232121) | Dragonfly Therapeutics | 2026-01-12 |
| Phase 1/2 Study of Mirdametinib + Vinblastine for Newly Diagnosed/Previously Untreated PLGG + Activation of MAPK (NCT06666348) | St. Justine's Hospital | 2026-01-12 |
| Effect of Vanzacaftor/Tezacaftor/Deutivacaftor (VNZ/TEZ/D-IVA) on the PK of Rosuvastatin in Healthy Participants (NCT07349394) | Vertex Pharmaceuticals Incorporated | 2026-01-12 |
| Safety and Tolerability Study of CTx1000 In Participants With Amyotrophic Lateral Sclerosis (NCT07401121) | Celosia Therapeutics Pty Ltd | 2026-01-12 |
| A Study of SGB-7342 in Subjects With Obesity or Overweight (NCT07324850) | Suzhou Sanegene Bio Inc. | 2026-01-12 |
| A Study of BL-M24D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors and Other Solid Tumors (NCT07279428) | Sichuan Baili Pharmaceutical Co., Ltd. | 2026-01-12 |
| Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) in Patients With Peritoneal Metastasis From Pancreatic Adenocarcinoma (NCT07253662) | Northwell Health | 2026-01-11 |
| Bacteriophage Therapy for Mycobacterium Abscessus Pulmonary Infection (NCT07228702) | Vancouver Coastal Health | 2026-01-11 |
| Clinical Efficacy of Antivet Versus Phosphoric Acid and Hydrochloric Acid in Microabrasion (NCT07709286) | Misr University for Science and Technology | 2026-01-10 |
| Chemotherapy Plus Pitavastatin Guided by Patient-Derived Tumor-like Cell Clusters in Refractory Non-Small Cell Lung Cancer (NCT07351565) | Chang Chen | 2026-01-10 |
| A Phase 1b Study of Lonitoclax + Azacitidine in Acute Myeloid Leukemia Patients (NCT07303660) | Lomond Therapeutics Holdings, Inc. | 2026-01-10 |
| A Study of SYH2069 Injection in Healthy Participants (NCT07736391) | CSPC Ouyi Pharmaceutical Co., Ltd. | 2026-01-10 |
| A First-in-Human Study of MEN2501 in Participants With Platinum-Resistant Ovarian Cancer (NCT07226427) | Stemline Therapeutics, Inc. | 2026-01-10 |
| ECC4703 Food Effect and Relative Bioavailability Study in Healthy Adult Participants (NCT07334080) | Eccogene | 2026-01-10 |
| A Clinical Study in Healthy Adults to See How the Body Processes and How Safe a Tablet That Combines Gemigliptin, Dapagliflozin, and Metformin is, Compared With Taking Zemiglo and Xigduo XR Together While Fasting. (NCT07399470) | LG Chem | 2026-01-09 |
| A Study to Assess the Mass Balance of [14C]HRS-8080 in Healthy Chinese Postmenopausal Female Subjects. (NCT07320521) | Shandong Suncadia Medicine Co., Ltd. | 2026-01-09 |
| Secretome vs. PRP Injections for Hair Density and Growth in Androgenetic Alopecia Patients (NCT07429253) | PT. Prodia Stem Cell Indonesia | 2026-01-09 |
| Bioequivalence Study of GZR18 Injection Before and After CMC Change (NCT07355738) | Gan & Lee Pharmaceuticals. | 2026-01-09 |
| A Study of AZD0120 in Autoimmune Diseases (NCT07295847) | AstraZeneca | 2026-01-09 |
| A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS) (NCT07290062) | Insmed Gene Therapy LLC | 2026-01-09 |
| Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression (NCT07155226) | AstraZeneca | 2026-01-09 |