| A Study to Compare the Pharmacokinetics of JHL1149 and Bevacizumab (Avastin) in Healthy Male Volunteers (NCT03576651) | JHL Biotech, Inc. | 2018-03-24 |
| Mass Balance Study With MT-7117 (NCT03503266) | Tanabe Pharma America, Inc. | 2018-03-23 |
| Single and Multiple Dose Study of ORIC-101 in Adult Healthy Subjects (NCT03835637) | ORIC Pharmaceuticals | 2018-03-23 |
| Histaminergic Basis of Central Fatigue in Multiple Sclerosis - A Novel Approach (NCT03266965) | University of Miami | 2018-03-23 |
| Single-dose Study of ANX007 in Participants With Primary Open-angle Glaucoma (NCT03488550) | Annexon, Inc. | 2018-03-23 |
| To Investigate the Multiple Dose Safety, Tolerability and Pharmacokinetics of WCK 4282 (FEP-TAZ) (NCT03622008) | Wockhardt | 2018-03-23 |
| Clinical Study of CAR-BCMA T in Patients With Refractory or Relapsed Multiple Myeloma (NCT03716856) | First Affiliated Hospital of Zhejiang University | 2018-03-23 |
| Buprenorphine-Fentanyl Interaction Study (NCT03747341) | Indivior Inc. | 2018-03-22 |
| A Phase 1 Dose-escalation Study of FF-10832 for Treatment of Solid Tumors Including Biliary Tract Cancer (NCT03440450) | Fujifilm Pharmaceuticals U.S.A., Inc. | 2018-03-22 |
| A Study of SHR6390 in Combination With Letrozole or Anastrozole or Fulvestrant in Patients With HR Positive and HER2 Negative Advanced Breast Cancer (NCT03481998) | Jiangsu HengRui Medicine Co., Ltd. | 2018-03-22 |
| Phase 1/2 Trial of Selinexor (KPT-330) With Docetaxel for Non-small Cell Lung Cancer (NSCLC) (NCT03095612) | University of Texas Southwestern Medical Center | 2018-03-22 |
| A Study of HLX06, a Humanized Monoclonal Antibody Targeting Human Vascular Endothelial Growth Factor Receptor-2 in Patients With Advanced Solid Tumors (NCT03494231) | Henlix, Inc | 2018-03-22 |
| Effect of BIA 5-1058 400 mg on the Steady State Pharmacokinetics of Sildenafil (NCT04994860) | Bial - Portela C S.A. | 2018-03-22 |
| Dose-escalation Study of IMC-001 in Subject With Metastatic or Locally-advanced Solid Tumors (NCT03644056) | ImmuneOncia Therapeutics Inc. | 2018-03-22 |
| MP0250 DARPin® Protein Plus Osimertinib in Patients With EGFR-mutated NSCLC (NCT03418532) | Molecular Partners AG | 2018-03-22 |
| B001 in Patients With CD20 Positive B-cell Non Hodgkin's Lymphoma (NCT03332121) | Shanghai Pharmaceuticals Holding Co., Ltd | 2018-03-22 |
| The University of Alabama at Birmingham (UAB) Neuroinflammation in Parkinson's Disease-TSPO- Positron Emission Tomography (PET) Substudy (NCT03457493) | University of Alabama at Birmingham | 2018-03-22 |
| A Study of Epacadostat and Nivolumab in Combination With Immune Therapies in Participants With Advanced or Metastatic Malignancies (ECHO-208) (NCT03347123) | Incyte Corporation | 2018-03-21 |
| Effect of Renal Impairment on Evobrutinib Pharmacokinetics (PK) (NCT03436394) | Merck KGaA, Darmstadt, Germany | 2018-03-21 |
| BAY2328065 Single Dose Escalation, Safety and Tolerability, Pharmacokinetics, Relative Bioavailability, Food Effect (NCT03427788) | Bayer | 2018-03-21 |
| Study to Determine the Single and Repeat Dose Pharmacokinetics, Food Effect, Proton Pump Inhibitor (PPI) Drug Interaction, Safety and Tolerability of Oral Prototype Formulations of BOS172767 in Healthy Subjects (NCT03464058) | Boston Pharmaceuticals | 2018-03-21 |
| Pain Biomarker Study (NCT03511846) | The University of Texas Health Science Center, Houston | 2018-03-21 |
| The Effect of Injection Site Cooling on Pain Experienced After the Administration of CNTX-4975-05 Into the Knee (NCT03472677) | Centrexion Therapeutics | 2018-03-21 |
| Preliminary Evaluation of Safety, Tolerability, and Efficacy of XT-150 for the Treatment of Osteoarthritic Pain (NCT03282149) | Xalud Therapeutics, Inc. | 2018-03-21 |
| Study of VX-121 in Healthy Subjects and in Subjects With Cystic Fibrosis (NCT03768089) | Vertex Pharmaceuticals Incorporated | 2018-03-20 |
| Navitoclax and Vistusertib in Treating Patients With Relapsed Small Cell Lung Cancer and Other Solid Tumors (NCT03366103) | National Cancer Institute (NCI) | 2018-03-20 |
| First-In-Human Study of BBT-401-1S Following Single and Multiple Ascending Doses in Healthy Volunteers (NCT03482648) | Bridge Biotherapeutics, Inc. | 2018-03-20 |
| Safety of Itacitinib in Combination With Corticosteroids for Treatment of Steroid-Naive Acute Graft-Versus-Host Disease in Japanese Subjects (NCT03497273) | Incyte Corporation | 2018-03-20 |
| Pharmacokinetic Study of Perampanel in Chinese Healthy Subjects (NCT03424564) | Eisai Co., Ltd. | 2018-03-20 |
| Study of Oral Edaravone in Healthy Adult Males (NCT04481750) | Shionogi | 2018-03-20 |
| A Phase 1 TP-271 Oral PK Multiple Ascending Dose Study (NCT03450187) | Tetraphase Pharmaceuticals, Inc | 2018-03-20 |
| HMPL004-6599 Phase I Dose-escalating Study (NCT03597971) | Nutrition Science Partners Limited | 2018-03-20 |
| Anhidrotic Area and Safety of MEDITOXIN in Healthy Male Valunteers (NCT03647982) | Medy-Tox | 2018-03-20 |
| Study of AG-120 and AG-881 in Subjects With Low Grade Glioma (NCT03343197) | Institut de Recherches Internationales Servier | 2018-03-20 |
| A Dose-escalation, Expansion Study of ARX788, in Advanced Solid Tumors Subjects With HER2 Expression (ACE-Pan Tumor 01) (NCT03255070) | Ambrx, Inc. | 2018-03-20 |
| Study of ISIS 681257 in Patients With Renal Impairment Compared to Healthy Patients (NCT03506854) | Akcea Therapeutics | 2018-03-20 |
| Dermatopharmacokinetic Trial of LEO 90100 Foam (NCT03476746) | LEO Pharma | 2018-03-20 |
| QUILT-3.067: NANT Triple Negative Breast Cancer (TNBC) Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With TNBC Who Have Progressed on or After Standard-of-care Therapy. (NCT03387085) | ImmunityBio, Inc. | 2018-03-19 |
| Study of Talimogene Laherparepvec With Atezolizumab for Triple Negative Breast Cancer and Colorectal Cancer With Liver Metastases (NCT03256344) | Amgen | 2018-03-19 |
| Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies (NCT03471260) | M.D. Anderson Cancer Center | 2018-03-19 |
| Safety and Pharmacokinetics of ODM-208 in Patients With Metastatic Castration-resistant Prostate Cancer (NCT03436485) | Orion Corporation, Orion Pharma | 2018-03-19 |
| Clinical Trial to Assess Safety and Efficacy of Autologous Cultured Epidermal Grafts Containing Epidermal Stem Cells Genetically Modified in Patients With JEB (HOLOGENE17) (NCT03490331) | Holostem s.r.l. | 2018-03-19 |
| Maraviroc on HIV-1 Infected Subjects Who Require Allogeneic Hematopoietic Cell Transplant (NCT03118661) | Washington University School of Medicine | 2018-03-19 |
| Study of CRISPR-Cas9 Mediated PD-1 and TCR Gene-knocked Out Mesothelin-directed CAR-T Cells in Patients With Mesothelin Positive Multiple Solid Tumors. (NCT03545815) | Chinese PLA General Hospital | 2018-03-19 |
| Thrombosomes® in Bleeding Thrombocytopenic Patients (NCT03394755) | Cellphire Therapeutics, Inc. | 2018-03-19 |
| Avelumab/Gemcitabine in Sarcomatoid RCC (NCT03483883) | Abramson Cancer Center at Penn Medicine | 2018-03-19 |
| Tolerability and Acceptability of Fibersol-2 in Children (NCT03565393) | International Centre for Diarrhoeal Disease Research, Bangladesh | 2018-03-19 |
| Eribulin and Radiation Therapy in Treating Patients With Retroperitoneal Liposarcoma That Can Be Removed by Surgery (NCT03361436) | OHSU Knight Cancer Institute | 2018-03-19 |
| Total Marrow and Lymphoid Irradiation Before Donor Transplant and Cyclophosphamide in Treating Patients With Acute Myeloid Leukemia (NCT03467386) | City of Hope Medical Center | 2018-03-19 |
| A Phase I Study of LuoXin Innovate (LXI-15028) in Healthy Chinese Subjects to Evaluate the Pharmacokinetics, Safety and Tolerability. (NCT03458650) | Shandong Luoxin Pharmaceutical Group Stock Co., Ltd. | 2018-03-19 |
| Safety, Tolerability and Pharmacodynamics of SYNB1020 (NCT03447730) | Synlogic | 2018-03-19 |
| The Effect of Itraconazole on BCT197 Exposure in Healthy Male Participants (NCT03498170) | Mereo BioPharma | 2018-03-19 |
| Tolerability of Cannabis in Patients Receiving Concurrent Chemoradiation for Glioblastoma (NCT03246113) | New York State Psychiatric Institute | 2018-03-19 |
| Allogeneic Human Mesenchymal Stem Cell Infusion vs Placebo in Alcohol Use Disorder and Major Depression. (NCT03265808) | Ihsan M Salloum, MD, MPH | 2018-03-18 |
| A First-in-Human Study of D-0502 Alone and in Combination With Palbociclib in Women With Advanced or Metastatic ER-Positive and HER2-Negative Breast Cancer (NCT03471663) | InventisBio Co., Ltd | 2018-03-18 |
| Phase 1 Food Effect Study for Alicaforsen Tablets (NCT03473626) | Atlantic Pharmaceuticals Ltd | 2018-03-16 |
| F-18 TFB-PET Studies in Cancer Patients Undergoing NIS-containing Viral Therapies (NCT03456908) | Mayo Clinic | 2018-03-16 |
| A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK, the Measure of How the Human Body Processes a Substance) of ETX0282 When Administered Orally to Healthy Participants (NCT03491748) | Entasis Therapeutics | 2018-03-16 |
| Retinoid 9cUAB30 in Producing a Biologic Effect in Patients With Early Stage Breast Cancer (NCT02876640) | National Cancer Institute (NCI) | 2018-03-16 |
| Tazemetostat in Treating Patients With Metastatic or Unresectable Solid Tumors or B-Cell Lymphomas With Liver Dysfunction (NCT03217253) | National Cancer Institute (NCI) | 2018-03-16 |
| Study Investigating the Safety and Efficacy of Blinatumomab in Combination With Pembrolizumab in Adults With Relapsed or Refractory Diffuse Large B Cell Lymphoma (DLBCL) (NCT03340766) | Amgen | 2018-03-16 |
| This Study Tests Different Doses of BI 1015550 in Patients With Idiopathic Pulmonary Fibrosis (IPF). The Study Tests How BI 1015550 is Taken up by the Body and How Well it is Tolerated. (NCT03422068) | Boehringer Ingelheim | 2018-03-16 |
| Pembrolizumab and Vorinostat Combined With Temozolomide for Newly Diagnosed Glioblastoma (NCT03426891) | H. Lee Moffitt Cancer Center and Research Institute | 2018-03-16 |
| Evaluating the Safety and Immunogenicity of Env (A,B,C,A/E)/Gag (C) DNA and gp120 (A,B,C,A/E) Protein/GLA-SE HIV Vaccines, Given Individually or Co-administered, in Healthy, HIV-1-Uninfected Adults (NCT03409276) | National Institute of Allergy and Infectious Diseases (NIAID) | 2018-03-16 |
| A Study in Healthy Male Volunteers to Look at How the Test Medicine GLPG1690 is Taken up by the Body When Doses of Itraconazole and Voriconazole Are Given to Healthy Volunteers (NCT03515382) | Lakefront Biotherapeutics NV | 2018-03-16 |
| Ibrutinib, Rituximab, Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With HIV-Positive Stage II-IV Diffuse Large B-Cell Lymphomas (NCT03220022) | National Cancer Institute (NCI) | 2018-03-16 |
| Combination Study of SV-BR-1-GM With Retifanlimab (NCT03328026) | BriaCell Therapeutics Corporation | 2018-03-16 |
| A Study Evaluating the Safety and Pharmacokinetics of ABBV-744 in Participants With Relapsed/Refractory Acute Myeloid Leukemia (AML) Cancer (NCT03360006) | AbbVie | 2018-03-16 |
| The Effect of Topiramate on Etonogestrel Concentrations in Contraceptive Implant Users (NCT03335163) | University of Colorado, Denver | 2018-03-15 |
| Second-line CM082 Combined With Paclitaxel For Patients With Advanced Gastric Cancer (NCT03286244) | AnewPharma | 2018-03-15 |
| On Demand Contraception: Ulipristal Acetate Plus a COX-2 Inhibitor at Peak Fertility (NCT03354117) | Stanford University | 2018-03-15 |
| Tolerance and Pharmacokinetics of TQB2450 (NCT03460457) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2018-03-15 |
| H-1337 Ophthalmic Solution Phase 1/2 (NCT03452033) | Allysta Pharmaceutical | 2018-03-15 |
| A Trial Investigating the Effect of Probenecid and Ciclosporin on the Concentrations of SNAC in Healthy Subjects (NCT03466567) | Novo Nordisk A/S | 2018-03-15 |
| A Meal Test Study of LY900014 in Participants With Type 1 Diabetes Mellitus (NCT03449433) | Eli Lilly and Company | 2018-03-15 |
| Stereotactic Body Radiotherapy (SBRT) Plus Immunotherapy for Cancer (NCT03431948) | University of Chicago | 2018-03-15 |
| The Effect of Platelet Rich Fibrin Matrix With and Without Peripheral Blood Mesenchymal Stem Cells on Implant Stability (NCT03044119) | KLE Society's Institute of Dental Sciences | 2018-03-15 |
| Glasdegib (PF-04449913) With Temozolomide Newly Diagnosed Glioblastoma (NCT03466450) | Grupo Español de Investigación en Neurooncología | 2018-03-15 |
| Sonodynamic Therapy Manipulates Atherosclerosis Regression Trial on Patients With PAD and Claudication (NCT03457662) | First Affiliated Hospital of Harbin Medical University | 2018-03-15 |
| A Positron Emission Tomography (PET) Study to Investigate P2X7 Receptor Occupancy by JNJ-55308942 Using [18F]-JNJ-64413739 (NCT03437590) | Janssen-Cilag International NV | 2018-03-15 |
| REVEAL Study of NKTR-262 in Combination With NKTR-214 and Nivolumab in Patients With Locally Advanced / Metastatic Solid Tumor Malignancies (NCT03435640) | Nektar Therapeutics | 2018-03-15 |
| Study Evaluating CMP-001 in Combination With Atezolizumab in Participants With Non-Small Cell Lung Cancer (NCT03438318) | Regeneron Pharmaceuticals | 2018-03-15 |
| A Study of Experimental Medication BMS-986231 in Patients With Different Levels of Kidney Function (NCT03332186) | Bristol-Myers Squibb | 2018-03-15 |
| Donor T Cell Therapy in Treating Immunocompromised Patients With Adenovirus-Related Disease (NCT03425526) | M.D. Anderson Cancer Center | 2018-03-15 |
| A Study of Atezolizumab in Combination With an Immunotherapy Agent Investigated With or Without Anti-Cd20 Therapy in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma (NCT03369964) | Hoffmann-La Roche | 2018-03-14 |
| Safety and Immunogenicity of a Candidate MERS-CoV Vaccine (MERS001) (NCT03399578) | University of Oxford | 2018-03-14 |
| Compassion Meditation for Cancer Survivor-Caregiver Dyads (NCT03459781) | Thaddeus Pace | 2018-03-14 |
| The Effect of Low Dose Intra-operative Ketamine on Closed-loop Controlled General Anesthesia (NCT03009409) | NeuroWave Systems Inc. | 2018-03-13 |
| Safety, Tolerability and Pharmacokinetics of SHP465 in Children Aged 4 to 5 Years With Attention-Deficit/Hyperactivity Disorder (ADHD) (NCT03327402) | Shire | 2018-03-13 |
| A Research Study Looking at a New Study Medicine (NNC0194-0499) for Weight Control in People With Overweight or Obesity (NCT03479892) | Novo Nordisk A/S | 2018-03-13 |
| First-time-in-Human (FTIH) Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single (in Both Fed and Fasted States) or Repeat Doses of GSK3358699 (NCT03426995) | GlaxoSmithKline | 2018-03-13 |
| The Acute Cardiovascular Effects of Nicotine in E-cigarettes (ACE) Study (NCT03010995) | University of Louisville | 2018-03-13 |
| Study of Gemcabene in Adults With FPLD (NCT03508687) | Elif Oral | 2018-03-13 |
| Study of SRF231 in Patients With Advanced Solid and Hematologic Cancers (NCT03512340) | Surface Oncology | 2018-03-13 |
| A Study of Glofitamab in Combination With Rituximab or Obinutuzumab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP), or Polatuzumab Vedotin Plus Rituximab, Cyclophosphamide, Doxorubicin, and Prednisone (CHP) in Participants With Non-Hodgkin Lymphomas or With DLBCL (NCT03467373) | Hoffmann-La Roche | 2018-03-13 |
| Avelumab Plus Autologous Dendritic Cell Vaccine in Pre-treated Metastatic Colorectal Cancer Patients (NCT03152565) | Grupo Espanol Multidisciplinario del Cancer Digestivo | 2018-03-12 |
| A Study to Compare the Pharmacokinetics (PK) of Single Subcutaneous (SC) Injections of Vedolizumab Administered in Prefilled Syringe (PFS) Versus (vs) Prefilled Syringe in Autoinjector (PFS+AI) in Healthy Participants (NCT03961308) | Takeda | 2018-03-12 |
| Treatment of Relapsed or Refractory Neuroblastoma and Osteosarcoma With Expanded Haploidentical NK Cells and Hu14.18-IL2 (NCT03209869) | University of Wisconsin, Madison | 2018-03-12 |
| A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Emicizumab in Healthy Chinese Volunteers (NCT03380780) | Hoffmann-La Roche | 2018-03-12 |
| Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory Cancers (NCT03017833) | M.D. Anderson Cancer Center | 2018-03-12 |