| T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery (NCT03190967) | National Cancer Institute (NCI) | 2018-04-18 |
| A Clinical Study to Evaluate the Safety, Tolerability, PK, PD, and Efficacy of KBP-089 in Patients With T2DM (NCT03907202) | KeyBioscience AG | 2018-04-17 |
| A Manufacturing Transfer Study Comparing the Bioequivalence of a Single Oral Dose of Claritin-D 12-Hour Extended Release Tablet From 2 Different Manufacturers Under Fasted Conditions in Healthy Adult Subjects (NCT03517930) | Bayer | 2018-04-17 |
| Safety, Tolerability, and Pharmacokinetic (PK) Study of DHES0815A in Participants With Human Epidermal Growth Factor Receptor (HER)2-Positive Breast Cancer (NCT03451162) | Genentech, Inc. | 2018-04-17 |
| Glutamate Reducing Interventions in Schizophrenia (NCT03321617) | New York State Psychiatric Institute | 2018-04-17 |
| A Study to Determine the Absorption, Metabolism, and Excretion of [14C]-E6007 After a Single Oral Administration in Healthy Male Participants (NCT03444818) | EA Pharma Co., Ltd. | 2018-04-17 |
| Single Ascending Dose Study of Lu AF76432 in Healthy Young Men (NCT03531229) | H. Lundbeck A/S | 2018-04-17 |
| A Study to Evaluate ICP-022 in Patients With CLL/ SLL (NCT03493217) | Beijing InnoCare Pharma Tech Co., Ltd. | 2018-04-17 |
| Extension Study of ABBV-8E12 in Patients With Progressive Supranuclear Palsy (PSP) Who Completed Study C2N-8E12-WW-104 (NCT03413319) | AbbVie | 2018-04-17 |
| Oral Liquid 13-cis-retinoic Acid (13-CRA) (NCT03291080) | Nova Laboratories Limited | 2018-04-17 |
| A Study to Evaluate the Pharmacokinetics of Avacopan (CCX168) in Participants With Mild or Moderate Hepatic Impairment (NCT06004934) | Amgen | 2018-04-17 |
| A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma (NCT03460977) | Pfizer | 2018-04-17 |
| Body Scan Activity on Bone Marrow Transplant Patients and Their Caregivers (NCT03611764) | Washington University School of Medicine | 2018-04-17 |
| A Bioequivalence Study of Isosorbide-5-Mononitrate Extended-Release Tablets Under Fed Conditions in Healthy Subjects (NCT03557580) | Qilu Pharmaceutical Co., Ltd. | 2018-04-17 |
| Safety and Tolerability of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With Phenylketonuria (NCT03516487) | Synlogic | 2018-04-17 |
| A Phase ⅠStudy of the Recombinant Mycobacterium Tuberculosis Vaccine Freeze-dried (NCT03026972) | Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. | 2018-04-16 |
| CKD-355 Drug-drug Interaction Study (CKD-355 DDI P1) (NCT03569579) | Chong Kun Dang Pharmaceutical | 2018-04-16 |
| Safety and Efficacy of rAAV2tYF-GRK1-RPGR in Subjects With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (NCT03316560) | Beacon Therapeutics | 2018-04-16 |
| A Phase 1/2 Study of FS118 in Patients With Advanced Malignancies (NCT03440437) | invoX Pharma Limited | 2018-04-16 |
| Pharmacodynamic and Safety of MBA-P01 in Healthy Male Volunteers (NCT03547141) | Medy-Tox | 2018-04-16 |
| A Study of Infacort® Versus Cortef® in Healthy Adult Male and Female Subjects (NCT03311932) | Neurocrine UK Limited | 2018-04-16 |
| Feasibility and Safety of Umbilical Cord Blood Transfusion in the Treatment of Neonatal Cerebral Ischemia and Anemia (NCT03352310) | Mononuclear Therapeutics Ltd. | 2018-04-16 |
| Assessing an Oral Janus Kinase Inhibitor, AZD4205, in Combination With Osimertinib in Patients Who Have Advanced Non-small Cell Lung Cancer (NCT03450330) | Dizal Pharmaceuticals | 2018-04-16 |
| A Multiple Dose Study of BAY1834845 in Healthy Male Subjects and in Patients With Psoriasis (NCT03493269) | Bayer | 2018-04-16 |
| Comparative Bioavailability Study of Sitagliptin/Metformin 50 mg/1000 mg Tablets in Healthy Male and Female Volunteers (NCT05549583) | Galenicum Health | 2018-04-15 |
| Use of Dexamethasone in Prevention of the Second Phase or a Biphasic Reaction of Anaphylaxis (NCT03523221) | Hamad Medical Corporation | 2018-04-15 |
| Metabolism of Deuterated NNN in Smokeless Tobacco Users (NCT02414477) | University of Minnesota | 2018-04-15 |
| Lu177-EB-PSMA617 Radionuclide Treatment in Patients With Metastatic Castration-resistant Prostate Cancer (NCT03780075) | Peking Union Medical College Hospital | 2018-04-15 |
| To Evaluate the Safety, Tolerability and Pharmacokinetics of K0706 in Plasma and Cerebrospinal Fluid in Healthy Volunteers (NCT03445338) | Sun Pharma Advanced Research Company Limited | 2018-04-15 |
| A Single Dose Study of SHR0410 in Healthy Male Participants (NCT03493191) | Atridia Pty Ltd. | 2018-04-15 |
| Lacosamide Effects on Alcohol Self Administration and Craving in Heavy Drinkers (NCT03271528) | Boston Medical Center | 2018-04-15 |
| Evaluation of the Abuse Liability of Very Low Nicotine (VLN) Cigarettes (NCT03559751) | 22nd Century Group, Inc. | 2018-04-13 |
| A Multiple Ascending Dose Study of HTD1801 in Adults With Hypercholesterolemia (NCT03381287) | HighTide Therapeutics (Hong Kong) Limited | 2018-04-13 |
| Ketogenic Diet in Combination With Standard-of-care Radiation and Temozolomide for Patients With Glioblastoma (NCT03451799) | Jethro Hu | 2018-04-13 |
| Safety and Tolerability of CS10BR05 Inj. in Subjects with Multiple System Atrophy (NCT03265444) | Corestemchemon, Inc. | 2018-04-13 |
| Fludeoxyglucose F-18-PET in Planning Lung Cancer Radiation Therapy (NCT03493789) | Emory University | 2018-04-13 |
| A Study to Evaluate Transplantation of Astrocytes Derived From Human Embryonic Stem Cells, in Patients With Amyotrophic Lateral Sclerosis (ALS) (NCT03482050) | Kadimastem | 2018-04-12 |
| Safety and Immunogenicity of ChAd63 RH5 and MVA RH5 in Adults, Young Children and Infants Living in Tanzania (NCT03435874) | University of Oxford | 2018-04-12 |
| Safety of FMT Using Oral Encapsulated PRIM-DJ2727 in HIV (NCT03329560) | The University of Texas Health Science Center, Houston | 2018-04-12 |
| Minimally Invasive Sensing of Beta-lactam Antibiotics (NCT03847610) | Imperial College London | 2018-04-12 |
| A Study in Evaluating Bioequivalence Between Test and Reference Formulations of Vadadustat Tablets in Healthy Adults (NCT03639155) | Akebia Therapeutics | 2018-04-12 |
| A Phase I Study of MSB2311 in Advanced Solid Tumors (NCT03463473) | Suzhou Transcenta Therapeutics Co., Ltd. | 2018-04-12 |
| A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of Praliciguat (IW-1973) in Healthy Volunteers (NCT03499106) | Cyclerion Therapeutics | 2018-04-12 |
| Estetrol (E4)/Drospirenone (DRSP) Drug-drug Interaction (DDI) Study (NCT03512860) | Estetra | 2018-04-12 |
| Study Evaluating the Antitumor Activity and Safety of Niraparib as Neoadjuvant Treatment in Participants With Breast Cancer (NCT03329937) | Tesaro, Inc. | 2018-04-12 |
| Clinical Evaluation of Adjusted Doses of Darunavir/Ritonavir With Rifampicin in HIV-infected Volunteers (NCT03892161) | University of Cape Town | 2018-04-12 |
| Infusion of Umbilical Cord Versus Bone Marrow Derived Mesenchymal Stem Cells to Evaluate Cytokine Suppression. (NCT03059355) | Joshua M Hare | 2018-04-12 |
| Cytoplasmic Activated PD-1 CAR T Cells in Refractory/Relapsed B Cell Lymphoma (NCT03540303) | Henan Cancer Hospital | 2018-04-12 |
| Study of Melphalan Flufenamide (Melflufen) + Dex With Bortezomib or Daratumumab in Patients With RRMM (NCT03481556) | Oncopeptides AB | 2018-04-12 |
| Concurrent Intrathecal-pemetrexed and Involved-field Radiotherapy for Leptomeningeal Metastasis From Solid Tumors (NCT03507244) | The First Hospital of Jilin University | 2018-04-12 |
| BCMA-CAR-T in Relapsed/Refractory Multiple Myeloma (NCT03664661) | Henan Cancer Hospital | 2018-04-11 |
| Trametinib and Trifluridine and Tipiracil Hydrochloride in Treating Patients With Colon or Rectal Cancer That is Advanced, Metastatic, or Cannot Be Removed by Surgery (NCT03317119) | City of Hope Medical Center | 2018-04-11 |
| Study of MN-166 (Ibudilast) Extended Release Tablet Formulations Compared With Capsules in Healthy Volunteers (NCT03533387) | MediciNova | 2018-04-11 |
| Effect of High-Dose Vitamin D3 in Smokers and Non-Smokers With and Without HIV (NCT03270709) | Emory University | 2018-04-11 |
| Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal Carcinomas (NCT03233724) | National Cancer Institute (NCI) | 2018-04-11 |
| Dose-escalating Phase I Trial With GEM333 in Patients With Acute Myeloid Leukemia (NCT03516760) | AvenCell Europe GmbH | 2018-04-11 |
| Nivolumab and Bevacizumab in Patients With Advanced and or Metastatic Hepatocellular Carcinoma (NCT03382886) | University of Utah | 2018-04-11 |
| Study in Pediatric Subjects Evaluating Pharmacokinetics and Safety of EXPAREL (NCT03485014) | Pacira Pharmaceuticals, Inc | 2018-04-10 |
| A Safety, Tolerability, Acceptability, and Pharmacokinetic (PK) Study of Cabotegravir (CAB) in Healthy Human Immunodeficiency Virus (HIV)-Uninfected Chinese Men (NCT03422172) | ViiV Healthcare | 2018-04-10 |
| Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Efavaleukin Alfa in Participants With Systemic Lupus Erythematosus (NCT03451422) | Amgen | 2018-04-10 |
| Phase I Study of RiMO-301 With Radiation in Advanced Tumors (NCT03444714) | Coordination Pharmaceuticals, Inc. | 2018-04-10 |
| Study in Healthy Subjects to Determine the Effect of an Inhibitor on Exposure to Relacorilant and Its Metabolites (NCT03512548) | Corcept Therapeutics | 2018-04-10 |
| A Study of UCB and MSCs in Children With CP: ACCeNT-CP (NCT03473301) | Joanne Kurtzberg, MD | 2018-04-10 |
| BIS-001-ER for the Treatment of Adult Focal Impaired Awareness Seizures (NCT03474770) | Supernus Pharmaceuticals, Inc. | 2018-04-10 |
| This Study in Healthy Men Tests How the Body Takes up BI 1467335 (NCT03483506) | Boehringer Ingelheim | 2018-04-10 |
| VAY736 in Combination With Ibrutinib in Patients With CLL on Ibrutinib (NCT03400176) | Novartis Pharmaceuticals | 2018-04-09 |
| Testing APPA-1 in Healthy Subjects and Osteoarthritis Patients (NCT07429565) | University of Liverpool | 2018-04-09 |
| SAD Phase I Study (First-in-human) to Investigate Contraloid Acetate (NCT03944460) | Prof. Dr. Dieter Willbold | 2018-04-09 |
| Safety and Immunogenicity of Rotavirus (Bio Farma) Vaccine in Adults, Children & Neonates (NCT03462108) | PT Bio Farma | 2018-04-09 |
| Adoptive Cell Therapy Long-term Follow-up (LTFU) Study (NCT03391778) | USWM CT, LLC | 2018-04-09 |
| Effect of BIA 5 1058 on Cardiac Repolarization (NCT03489005) | Bial - Portela C S.A. | 2018-04-09 |
| Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MRG-110 Following Intradermal Injection in Healthy Volunteers (NCT03603431) | miRagen Therapeutics, Inc. | 2018-04-09 |
| A Study to Evaluate the Effects of Single-dose Seltorexant on Electrocardiogram Intervals in Healthy Adult Participants (NCT03494907) | Janssen Research & Development, LLC | 2018-04-09 |
| TLR9 Agonist SD-101, Anti-OX40 Antibody BMS 986178, and Radiation Therapy in Treating Patients With Low-Grade B-Cell Non-Hodgkin Lymphomas (NCT03410901) | Ronald Levy | 2018-04-09 |
| PD-1 Inhibition to Determine CNS Reservoir of HIV-Infection (NCT03239899) | National Institute of Neurological Disorders and Stroke (NINDS) | 2018-04-09 |
| Drug-drug Interaction Between Belumosudil, Itraconazole, Rifampicin, Rabeprazole, and Omeprazole in Healthy Volunteers (NCT03530995) | Kadmon Corporation, LLC | 2018-04-09 |
| Novel INXN-4001 Triple Effector Plasmid in Heart Failure (NCT03409627) | Triple-Gene, LLC | 2018-04-09 |
| Oral Glutathione As A Skin Whitening Agent (NCT04105504) | Dr Irma Bernadette S Sitohang | 2018-04-08 |
| A Study to Investigate the Safety, Tolerability and Pharmacokinetics of RD01 (Pegerythropoietin) in Healthy Chinese Volunteers (NCT03657238) | Shengzhen Sciprogen Bio-pharmaceutical Co. Ltd | 2018-04-08 |
| Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of After Administrations of DWP14012 Alone and Combinations of DWP14012, Clarithromycin and Amoxicillin in Healthy Male Subjects (NCT03487562) | Daewoong Pharmaceutical Co. LTD. | 2018-04-08 |
| Effects of Vitamin C Administration on Extravascular Lung Water in Patients With Severe Features of Preeclampsia (NCT03451266) | University Medical Centre Ljubljana | 2018-04-07 |
| Bioequivalence of Sitagliptin Phosphate/Metformin Hydrochloride Tablets in Healthy Chinese Subjects (NCT04877106) | The Affiliated Hospital of Qingdao University | 2018-04-07 |
| Rogaratinib (BAY1163877) Human Mass Balance Study (NCT03484585) | Bayer | 2018-04-06 |
| Pharmacokinetic Study Evaluating Staccato® Alprazolam 1 mg Inhaler in Smokers Versus Non-Smokers (NCT03516305) | Engage Therapeutics, Inc. | 2018-04-06 |
| Bioequivalence Study of Clopid® (Clopidogrel) 75 mg Tablet and Plavix® 75 mg Tablet After Oral Administration to Healthy Adult Subjects Under Fasting Condition (NCT05186129) | Center for Bioequivalence Studies and Clinical Research | 2018-04-06 |
| VNRX-5133 With VNRX-5022 in Subjects With Varying Degrees of Renal Impairment (NCT03690362) | Venatorx Pharmaceuticals, Inc. | 2018-04-06 |
| Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging (NCT03417830) | GlaxoSmithKline | 2018-04-06 |
| A Study of TAS0728 in Patients With Solid Tumors With HER2 or HER3 Abnormalities (NCT03410927) | Taiho Oncology, Inc. | 2018-04-06 |
| Ureter Identification With IRDye 800BK (NCT03387410) | Oxford University Hospitals NHS Trust | 2018-04-06 |
| Bioequivalence Study of CJ-30060 in Healthy Male Volunteers (NCT03639493) | HK inno.N Corporation | 2018-04-06 |
| Safety and Pharmacokinetics of NP10679 in Normal Healthy Volunteers (NCT03565861) | Neurop Inc. | 2018-04-06 |
| Outpatient Administration of R-DHAP in Relapsed/Refractory Non-Hodgkin Lymphoma (NCT03892421) | La Raza Medical Center | 2018-04-05 |
| 89Zr-girentuximab ) Dosimetry in CCRC Study - ZIR-DOSE (NCT03556046) | Radboud University Medical Center | 2018-04-05 |
| A Study of PRX004 in Subjects With Amyloid Transthyretin (ATTR) Amyloidosis (NCT03336580) | Prothena Biosciences Limited | 2018-04-05 |
| An Investigational Immunotherapy Study of BMS-986299 Alone and in Combination With Nivolumab and Ipilimumab in Participants With Solid Cancers That Have Spread or Cannot be Removed (NCT03444753) | Bristol-Myers Squibb | 2018-04-05 |
| A Study to Compare the Pharmacokinetics of Different Oral Formulations of FDL169 in Healthy Subjects (NCT03527095) | Flatley Discovery Lab LLC | 2018-04-05 |
| A Study of Niraparib as Single Agent in Participants With Advanced Solid Tumors (NCT03497429) | Takeda | 2018-04-05 |
| A Study to Assess the Effectiveness and Side Effects of GSK2798745 in Participants With Chronic Cough (NCT03372603) | GlaxoSmithKline | 2018-04-05 |
| Study to Evaluate Safety & Efficacy of FLX-787-ODT to Treat Fasciculations in Tongue and Appendicular Muscle in Adult Subjects With ALS (NCT03334786) | Flex Pharma, Inc. | 2018-04-05 |
| A Study of Erdafitinib in Participants With Metastatic or Locally Advanced Urothelial Cancer (NCT03473743) | Janssen Research & Development, LLC | 2018-04-05 |