| A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignancies (NCT03652077) | Incyte Corporation | 2018-09-24 |
| [18F]Fluciclovine and [18F]FLT PET/CT Assessment of Primary High-Grade Brain Tumors (NCT03276676) | University of Utah | 2018-09-24 |
| A Study to Assess the Electrophysiology, Safety, Tolerability, and Pharmacokinetics of SAGE-718 Using a Ketamine Challenge in Healthy Subjects (NCT03771586) | Supernus Pharmaceuticals, Inc. | 2018-09-24 |
| Cytokine Microdialysis for Real-Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade (NCT03493932) | National Institute of Neurological Disorders and Stroke (NINDS) | 2018-09-24 |
| PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery (NCT03218826) | National Cancer Institute (NCI) | 2018-09-24 |
| Evaluation of the Pharmacokinetics of Tropifexor in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared to Healthy Control Subjects (NCT03681457) | Novartis Pharmaceuticals | 2018-09-24 |
| Placebo Controlled, Dose Escalation Study to Evaluate Safety, Pharmacokinetics & Efficacy of SAP-001 in Gout Patients (NCT03857165) | Shanton Pharma Co., Ltd. | 2018-09-24 |
| Safety and Immunogencity of H7N9 Influenza Antigen With 2 Adjuvant Formulations in Healthy Adults in Brazil (NCT03330899) | Butantan Institute | 2018-09-24 |
| REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma (NCT03690869) | Regeneron Pharmaceuticals | 2018-09-24 |
| PF 06412562 in Subjects With Advanced Stage Parkinson's Disease (NCT03665454) | Milton S. Hershey Medical Center | 2018-09-24 |
| A Pilot Study of Hormonal Therapy Combined With Central Memory T Cells (Tcm) for Patients With Advanced Prostate Cancer (NCT03587285) | Guangzhou University of Traditional Chinese Medicine | 2018-09-23 |
| A STUDY TO ESTIMATE THE EFFECT OF PF-06651600 ON THE PHARMACOKINETICS (PK) OF ORAL CONTRACEPTIVE (OC) (NCT03608241) | Pfizer | 2018-09-21 |
| DS-1205c With Gefitinib for Metastatic or Unresectable Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Small Cell Lung Cancer (NCT03599518) | Daiichi Sankyo Co., Ltd. | 2018-09-21 |
| Ferumoxytol as a Contrast Agent for Pulmonary Magnetic Resonance Angiography (NCT03173066) | Brigham and Women's Hospital | 2018-09-21 |
| Sensitivity of Pharmacokinetics to Differences in Particle Size Distribution of Suspension-based Nasal Sprays (NCT02588326) | University of Florida | 2018-09-21 |
| Nivolumab With or Without Ipilimumab in Treating Patients With Recurrent or High Grade Gynecologic Cancer With Metastatic Peritoneal Carcinomatosis (NCT03508570) | M.D. Anderson Cancer Center | 2018-09-21 |
| Bioequivalence Study of Clavamox, Film-coated Tablets, 875 mg + 125 mg Pharmtechnology LLC, Belarus), and Augmentin®, Film-coated Tablets, 875 mg + 125 mg (GlaxoSmithKline Trading CJSC, Russia), in Healthy Volunteers Under Fasting Conditions (NCT03702894) | Pharmtechnology LLC | 2018-09-21 |
| Comparative Study of Pharmacokinetics, Pharmacodynamics, Safety, and Immunogenicity of Single Intravenous Doses of BCD-148 and Soliris® (NCT04027803) | Biocad | 2018-09-21 |
| Study of ICP-105 in Solid Tumors Patients (NCT03642834) | Beijing InnoCare Pharma Tech Co., Ltd. | 2018-09-21 |
| Olaratumab Plus Trabectedin in Advanced Soft-tissue Sarcoma Patients Soft-tissue Sarcoma Patients (NCT03985722) | Grupo Espanol de Investigacion en Sarcomas | 2018-09-21 |
| The Safety, Tolerability and Pharmacokinetic Study of ZSP1273 in Healthy Volunteers. (NCT03679143) | Guangdong Zhongsheng Pharmaceutical Co., Ltd. | 2018-09-20 |
| Safety, Tolerability, and Pharmacokinetics of Clesrovimab (MK-1654) in Infants (MK-1654-002) (NCT03524118) | Merck Sharp & Dohme LLC | 2018-09-20 |
| Grapiprant and Pembrolizumab in Patients With Advanced or Progressive MSS Colorectal Cancer (NCT03658772) | Arrys Therapeutics | 2018-09-20 |
| Single Ascending Dose (SAD) and Multiple Ascending Dose (MAD) Study of M5049 in Healthy Participants (NCT03676322) | Merck KGaA, Darmstadt, Germany | 2018-09-20 |
| India Dexamethasone and Betamethasone (NCT03668860) | Children's Hospital Medical Center, Cincinnati | 2018-09-20 |
| To Evaluate Safety, Tolerability, and Clinical Activity of the Antibody-drug Conjugate, GSK2857916 Administered in Combination With Lenalidomide Plus Dexamethasone (Arm A), or in Combination With Bortezomib Plus Dexamethasone (Arm B) in Participants With Relapsed/Refractory Multiple Myeloma (RRMM) (NCT03544281) | GlaxoSmithKline | 2018-09-20 |
| A Phase 1 Study to Assess the Safety of NLY01 in Healthy Subjects (NCT03672604) | Neuraly, Inc. | 2018-09-19 |
| To Demonstrate Equivalent Pharmacokinetic Properties of HD204 and Bevacizumab (Avastin®) in Healthy Male Subjects (NCT03390673) | Prestige Biopharma Limited | 2018-09-19 |
| Safety of Blood Stem Cell Mobilization With Plerixafor in Patients With Sickle Cell Disease (NCT03664830) | City of Hope Medical Center | 2018-09-19 |
| DEPLETHINK - LymphoDEPLEtion and THerapeutic Immunotherapy With NKR-2 (NCT03466320) | Celyad Oncology SA | 2018-09-18 |
| A Study in Healthy Subjects to Investigate Whether Administration of Clazosentan Can Affect Normal Heart Function (NCT03657446) | Idorsia Pharmaceuticals Ltd. | 2018-09-18 |
| A Study to Evaluate the Effect of MCI-186 at Therapeutic and Supra-Therapeutic Doses on the QT Interval(QT)/Corrected QT Interval(QTc) Interval in Healthy Subjects (NCT04029090) | Shionogi | 2018-09-18 |
| Imaging the HIV Reservoir (NCT03063788) | Bayside Health | 2018-09-18 |
| Study of Anlotinib Combined With Gemcitabine/Cisplatin in Advanced Nasopharyngeal Carcinoma (NCT03639467) | Chinese Academy of Medical Sciences | 2018-09-18 |
| A Study to Try to Bring Back Radioiodine Sensitivity in Patients With Advanced Thyroid Cancer. (NCT03469011) | AHS Cancer Control Alberta | 2018-09-18 |
| A Study in Participants With Epilepsy, to Evaluate the Pharmacokinetics, Safety and Tolerability of Oxcarbazepine on Padsevonil (NCT03695094) | UCB Biopharma S.P.R.L. | 2018-09-18 |
| Testing the Addition of an Immunotherapy Agent, Atezolizumab, When Given With the Usual Chemo-Immunotherapy Drug Combination (Rituximab Plus Gemcitabine and Oxaliplatin) for Relapsed/Refractory (That Has Come Back or Not Responded to Treatment) Transformed Diffuse Large B-Cell Lymphoma (NCT03321643) | National Cancer Institute (NCI) | 2018-09-18 |
| Safety and Pharmacokinetics of a Single Dose of CCH (3.36 mg) in Subjects With EFP (NCT03675685) | Endo USA Inc., a Keenova Therapeutics Company | 2018-09-18 |
| Study of CVN424 in Healthy Subjects (NCT03657030) | Cerevance Beta, Inc. | 2018-09-18 |
| Study of CD137 Agonist ADG106 With Advanced or Metastatic Solid Tumors and/or Non-Hodgkin Lymphoma (NCT03707093) | Adagene Inc | 2018-09-17 |
| A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib (NCT03723395) | Seagen Inc. | 2018-09-17 |
| A Study to Evaluate the Safety of THR-687 in Subjects With Diabetic Macular Edema (DME) (NCT03666923) | ThromboGenics | 2018-09-17 |
| Effects of Ketone Bodies on Cognition in Type 2 Diabetes (NCT03657537) | Bispebjerg Hospital | 2018-09-17 |
| S.C. Immunotherapy With BM41 in Patients With Allergic Rhino-conjunctivitis Caused by Birch Pollen (NCT04912076) | Odense University Hospital | 2018-09-17 |
| Vasopressin and Pain Perception in the Brain (NCT03446456) | University of Maryland, Baltimore | 2018-09-17 |
| Alternative Neoadjuvant Chemotherapy in Resectable and Borderline Resectable Pancreatic Cancer (NCT03703063) | Benaroya Research Institute | 2018-09-17 |
| Trial of KN026 in Patients With HER2-positive Advanced Malignant Breast Cancer and Gastric Cancer (NCT03619681) | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | 2018-09-17 |
| Omacetaxine + Azacitidine in Untreated Patients With High Grade MDS (NCT03564873) | University of Colorado, Denver | 2018-09-17 |
| Study of the Safety and Efficacy of APR-246 in Combination With Azacitidine (NCT03588078) | Groupe Francophone des Myelodysplasies | 2018-09-15 |
| RBT-1 Phase 1b Clinical Trial in Healthy Volunteers and Subjects With CKD (NCT03630029) | Renibus Therapeutics, Inc. | 2018-09-15 |
| Trial to Evaluate the Safety, Immunogenicity, and Efficacy of Malaria Infection in Malaria Naïve Adults (NCT03341754) | U.S. Army Medical Research and Development Command | 2018-09-15 |
| Use of Intranasal Oxytocin During Detoxification of Crack Cocaine (NCT04306354) | Pontificia Universidade Católica do Rio Grande do Sul | 2018-09-15 |
| MitoQ for Fatigue in Multiple Sclerosis (NCT03166800) | Oregon Health and Science University | 2018-09-15 |
| T Cells Expressing a Novel Fully-Human Anti-BCMA CAR for Treating Multiple Myeloma (NCT03602612) | National Cancer Institute (NCI) | 2018-09-14 |
| Effect of Flavonoids on Gut Permeability in Cyclists (NCT03427879) | Utah State University | 2018-09-14 |
| Nivolumab and Tocilizumab for Relapsed Hematological Malignancy Post-allogeneic Transplant (NCT03588936) | Medical College of Wisconsin | 2018-09-14 |
| To Evaluate the Safety and Tolerability, Pharmacokinetics, Food-effect and Pharmacodynamics of EHP-101 in Healthy Volunteers (NCT03745001) | Emerald Health Pharmaceuticals | 2018-09-14 |
| Safety, Tolerability, PK, PD, and Efficacy of AMG 427 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (NCT03541369) | Amgen | 2018-09-14 |
| Neoantigen DNA Vaccine in Combination With Nivolumab/Ipilimumab and PROSTVAC in Metastatic Hormone-Sensitive Prostate Cancer (NCT03532217) | Washington University School of Medicine | 2018-09-14 |
| Gemtuzumab Ozogamicin With G-CSF, Cladribine, Cytarabine & Mitoxantrone for Untreated AML & High-Grade Myeloid Neoplasm (NCT03531918) | Fred Hutchinson Cancer Center | 2018-09-14 |
| A First in Human Study in Healthy Volunteers and in Participants With Frontotemporal Dementia With Granulin (GRN) Mutation (NCT03636204) | Alector Inc. | 2018-09-14 |
| AAVCAGsCD59 for the Treatment of Wet AMD (NCT03585556) | Janssen Research & Development, LLC | 2018-09-13 |
| Modified T Cells, Chemotherapy, and Aldesleukin With or Without LV305 and CMB305 in Treating Participants With Advanced or Recurrent Sarcoma (NCT03450122) | M.D. Anderson Cancer Center | 2018-09-13 |
| Embolization for the Treatment of Pain Secondary to Adhesive Capsulitis (NCT03676829) | Vascular Institute of Virginia | 2018-09-13 |
| Drug Interaction Study Evaluating the Effect of Rifampin on PK and Safety of PF 04965842. (NCT03637790) | Pfizer | 2018-09-13 |
| Combination of Fimasartan/Amlodipine/Hydrochlorothiazide in Healthy Male Subjects (NCT03629067) | Boryung Pharmaceutical Co., Ltd | 2018-09-13 |
| Efficacy of Treatment of Postpartum Anaemia With Intravenous Iron Versus Oral Iron in a Tertiary Hospital in South East, Nigeria. (NCT07110935) | Federal Teaching Hospital Abakaliki | 2018-09-13 |
| Mass Balance Recovery and Metabolite Profile of CORT125281 in Healthy Male Participants (NCT03877952) | Corcept Therapeutics | 2018-09-13 |
| CAR-T Intraperitoneal Infusions for CEA-Expressing Adenocarcinoma Peritoneal Metastases or Malignant Ascites (IPC) (NCT03682744) | Sorrento Therapeutics, Inc. | 2018-09-13 |
| REcycled CartiLage Auto/Allo IMplantation (NCT03672825) | Mayo Clinic | 2018-09-13 |
| Safety and Tolerability of SH-1028 in Patients With Advanced Solid Cancer (NCT03618043) | Nanjing Sanhome Pharmaceutical, Co., Ltd. | 2018-09-13 |
| Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma (NCT03681561) | Veronika Bachanova | 2018-09-13 |
| Drug Drug Interaction Study Evaluating the Effect of Fluvoxamine or Fluconazole on PK and Safety of PF-04965842. (NCT03634345) | Pfizer | 2018-09-12 |
| Research Study of a New Medicine (NNC9204-1706) in People With Overweight or Obesity (NCT03661879) | Novo Nordisk A/S | 2018-09-12 |
| BIIB092 in Primary Tauopathies: CBS, nfvPPA, sMAPT, and TES (NCT03658135) | University of California, San Francisco | 2018-09-12 |
| MIBG With Dinutuximab +/- Vorinostat (NCT03332667) | New Approaches to Neuroblastoma Therapy Consortium | 2018-09-12 |
| Phase 1 Study of BAY1905254 - An Early Clinical Research Study to Evaluate a New Drug Called Bapotulimab (BAY1905254) in the Expansion Cohort in Combination With Pembrolizumab in Head and Neck Cancer That Has Returned or is Discovered to be Metastatic and is Expressing PDL1. (NCT03666273) | Bayer | 2018-09-12 |
| A Study to Evaluate the Safety and Tolerability of AB154 in Participants With Advanced Malignancies (NCT03628677) | Arcus Biosciences, Inc. | 2018-09-12 |
| An Investigational Immunotherapy Study of BMS-986310 Administered Alone and in Combination With Nivolumab in Patients With Advanced Solid Tumors (NCT03661632) | Bristol-Myers Squibb | 2018-09-11 |
| A Phase I Study to Study the PK and Safety of Single Doses of STS101, DHE Injection and Nasal Spray in Healthy Subjects (NCT03874832) | Satsuma Pharmaceuticals, Inc. | 2018-09-11 |
| Bioequivalence of Cefprozil Granule in Healthy Chinese Volunteers (NCT04414254) | The Affiliated Hospital of Qingdao University | 2018-09-11 |
| M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers (NCT03554473) | National Cancer Institute (NCI) | 2018-09-11 |
| An Investigational Study to Evaluate Experimental Medication BMS-986036 in Participants With Different Levels of Kidney Function (NCT03674476) | Bristol-Myers Squibb | 2018-09-11 |
| Effect of Copanlisib on Metformin Pharmacokinetics and Pharmacodynamics (NCT03655301) | Bayer | 2018-09-11 |
| Vorolanib (X-82) Combined With Checkpoint Inhibitors in Patients With Solid Tumors (NCT03511222) | Washington University School of Medicine | 2018-09-11 |
| Intense Treatment Regimen With Intravitreal Aflibercept Injection (NCT03594461) | Vitreous -Retina- Macula Consultants of New York | 2018-09-11 |
| A Study in Healthy Men to Find Out How BI 425809 is Taken up and Handled by the Body (NCT03654170) | Boehringer Ingelheim | 2018-09-11 |
| A Phase 1 Study Evaluating the Safety, Tolerability and Efficacy of AMG 119 in Subjects With RR SCLC (NCT03392064) | Amgen | 2018-09-10 |
| A Study of Benzonatate Soft Capsule in Chinese Healthy Subjects (NCT03922373) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2018-09-10 |
| Lenalidomide in Anti-MAG Neuropathy: Phase 1b Study (NCT03701711) | Ohio State University | 2018-09-10 |
| Imaging Inflammation in Alzheimer's Disease With 11C-ER176 (NCT03744312) | Columbia University | 2018-09-10 |
| Combination Therapy With 3BNC117 and 10-1074 in HIV-Infected Individuals (NCT03571204) | National Institute of Allergy and Infectious Diseases (NIAID) | 2018-09-10 |
| Venetoclax, Carmustine, Etoposide, Cytarabine, and Melphalan Before Stem Cell Transplant in Treating Participants With Relapsed or Refractory Non-Hodgkin Lymphoma (NCT03583424) | Ohio State University Comprehensive Cancer Center | 2018-09-10 |
| MCS110 With BRAF/MEK Inhibition in Patients With Melanoma (NCT03455764) | Dana-Farber Cancer Institute | 2018-09-10 |
| A Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB078 in Adults With C9ORF72-Associated Amyotrophic Lateral Sclerosis (NCT03626012) | Biogen | 2018-09-10 |
| Taste-masking Study for Tricaprilin in Sensory Panelists (NCT03628352) | Cerecin | 2018-09-10 |
| Study of TG-1701, an Irreversible Bruton's Tyrosine Kinase Inhibitor, in Patients With B-Cell Malignancies (NCT03671590) | TG Therapeutics, Inc. | 2018-09-10 |
| A Study in Healthy Men to Test How BI 730357 is Processed by the Body (NCT03664011) | Boehringer Ingelheim | 2018-09-10 |
| A Bioequivalence Study of Dasatinib Tablet (NCT05640804) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2018-09-09 |
| A Methodology Development Environmental Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis (NCT03660878) | Aldeyra Therapeutics, Inc. | 2018-09-08 |