| Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of DWP14012 After Oral Administration in Healthy Japanese, Caucasian and Korean (NCT03574415) | Daewoong Pharmaceutical Co. LTD. | 2018-11-01 |
| Study of PD-1 Gene-knocked Out Mesothelin-directed CAR-T Cells With the Conditioning of PC in Mesothelin Positive Multiple Solid Tumors (NCT03747965) | Chinese PLA General Hospital | 2018-11-01 |
| Acute Pain Management in Patients on Opioid Replacement Therapy (NCT03933865) | University of California, San Francisco | 2018-10-31 |
| Phase I Trial of Endoxifen Gel Versus Placebo in Women Undergoing Breast Surgery (NCT03317405) | National Cancer Institute (NCI) | 2018-10-31 |
| Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome (NCT03661307) | M.D. Anderson Cancer Center | 2018-10-31 |
| RO5126766 for Patients With Advanced KRAS-Mutant Lung Cancer (NCT03681483) | Memorial Sloan Kettering Cancer Center | 2018-10-31 |
| Neoantigen-based Personalized Vaccine Combined With Immune Checkpoint Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma (NCT03422094) | Washington University School of Medicine | 2018-10-31 |
| A Study to Evaluate Different Dose Levels of GlaxoSmithKline (GSK) Biologicals' Investigational Respiratory Syncytial Virus (RSV) Vaccine (GSK3888550A), Based on the Vaccine Safety and the Antibodies (Body Defences) Produced Following Vaccine Administration, When Given to Healthy Non-pregnant Women (NCT03674177) | GlaxoSmithKline | 2018-10-30 |
| Human Absorption, Distribution, Metabolism and Excretion (ADME) of [14C]-Evobrutinib (NCT03725072) | Merck KGaA, Darmstadt, Germany | 2018-10-30 |
| Study of the Effect NT-I7 on CD4 Counts in Patients With High Grade Gliomas (NCT02659800) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2018-10-30 |
| SBRT-based PArtial Tumor Irradiation of HYpoxic Segment (NCT04168320) | Klinikum Klagenfurt am Wörthersee | 2018-10-30 |
| Anti-CD19/BCMA Bispecific CAR-T Cell Therapy for R/R MM (NCT03706547) | Peng Liu | 2018-10-30 |
| A Phase I Clinical Trial of BAT5906 Injection in Patients With Wet Age-related Macular Degeneration (NCT04151212) | Bio-Thera Solutions | 2018-10-30 |
| Rituximab + Immunotherapy in Follicular Lymphoma (NCT03636503) | Dana-Farber Cancer Institute | 2018-10-30 |
| An Efficacy Study of IV Boosting With ChAd63/MVA ME-TRAP (NCT03707353) | University of Oxford | 2018-10-30 |
| Pharmacological Activation of HMN for OSA (NCT03640052) | Brigham and Women's Hospital | 2018-10-30 |
| Nitrous Oxide- Suicidal Ideation (NCT03736538) | Washington University School of Medicine | 2018-10-30 |
| A Study of CS1003 in Subjects With Advanced Solid Tumors or Lymphomas (NCT03809767) | CStone Pharmaceuticals | 2018-10-29 |
| A Study of Subcutaneous Nivolumab Monotherapy With or Without Recombinant Human Hyaluronidase PH20 (rHuPH20) (NCT03656718) | Bristol-Myers Squibb | 2018-10-29 |
| IVIG (Gamunex-C) Treatment Study for POTS Subjects (NCT03919773) | University of Texas Southwestern Medical Center | 2018-10-29 |
| Evaluate the Tolerance, Safety and Pharmacokinetics of Germinal Peptide Eye Drops in Healthy Volunteers (NCT03662971) | Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. | 2018-10-29 |
| Study of PTC299 (Emvododstat) in Relapsed/Refractory Acute Leukemias (NCT03761069) | PTC Therapeutics | 2018-10-29 |
| Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 562 in Subjects With r/r Diffuse Large B-cell Lymphoma, Mantle Cell Lymphoma, or Follicular Lymphoma (NCT03571828) | Amgen | 2018-10-29 |
| Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL (NCT03602157) | UNC Lineberger Comprehensive Cancer Center | 2018-10-29 |
| Low-dose Interleukin-2 and Pembrolizumab in Melanoma and Renal Cell Cancer (NCT03111901) | William Grosh, MD | 2018-10-29 |
| A Combination of Avelumab and Taxane (AVETAX) for Urothelial Cancer (NCT03575013) | Yousef Zakharia | 2018-10-29 |
| COMPARISON OF A NEW FORMULATION OF GOSERELIN (Pepti 3.6 mg) to Zoladex® 3.6 mg (NCT04428684) | Peptigroupe Inc. | 2018-10-29 |
| Fluorescence Endoscopy of Esophageal Carcinoma (NCT03558724) | University Medical Center Groningen | 2018-10-29 |
| A Pharmacokinetic Study of Omaveloxolone in Healthy Volunteers (NCT03664453) | Biogen | 2018-10-29 |
| Long-Term Follow-Up Study for Subjects Treated With P-BCMA-101 (NCT03741127) | Poseida Therapeutics, Inc. | 2018-10-29 |
| Study to Compare Pharmacokinetic Property of SYO-1644 Tab. and Nexavar Tab. in Healthy Male Volunteers (NCT03674060) | Samyang Biopharmaceuticals Corporation | 2018-10-28 |
| Gene Delivery Clinical Trial of SRP-9003 (Bidridistrogene Xeboparvovec) for Participants With Limb-Girdle Muscular Dystrophy, Type 2E (LGMD2E) (Beta-Sarcoglycan Deficiency) (NCT03652259) | Sarepta Therapeutics, Inc. | 2018-10-27 |
| Mesenchymal Stem Cells for Prevention of Bronchopulmonary Dysplasia in Infants (NCT03631420) | Meridigen Biotech Co., Ltd. | 2018-10-26 |
| CGB-400 for the Reduction of Facial Redness (NCT04508660) | CAGE Bio Inc. | 2018-10-26 |
| Osimertinib With Stereotactic Radiosurgery (SRS) in Brain Metastases From EGFR Positive NSCLC (NCT03535363) | Case Comprehensive Cancer Center | 2018-10-26 |
| A Study of LY3361237 in Healthy Participants (NCT03695198) | Eli Lilly and Company | 2018-10-26 |
| CGB-400 for the Reduction of Facial Redness and Bumps and Blemishes (NCT04508205) | CAGE Bio Inc. | 2018-10-26 |
| A Research Study Looking at How Faster Aspart Injected in Double Concentration Works in the Body of People With Type 1 Diabetes Mellitus (NCT03723759) | Novo Nordisk A/S | 2018-10-26 |
| Clinical Study on Anti-tumor Effect Induced by Activated Primary Natural Killer（NK）Cells (NCT03634501) | Xuanwu Hospital, Beijing | 2018-10-26 |
| Relative Bioavailability and Drug-drug Interaction Study With MT-7117 and a Proton Pump Inhibitor (NCT03688022) | Tanabe Pharma America, Inc. | 2018-10-25 |
| Daratumumab, Bortezomib, Dexamethasone, Pegylated Liposomal Doxorubicin Hydrochloride, and Lenalidomide in Treating Participants With Plasma Cell Leukemia (NCT03591744) | City of Hope Medical Center | 2018-10-25 |
| Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses of MGL-3196 in Subjects With Varying Degrees of Hepatic Impairment and Healthy Matched Control Subjects (NCT04643795) | Madrigal Pharmaceuticals, Inc. | 2018-10-25 |
| Study of Oraxol and Pembrolizumab in Subjects With Advanced Solid Tumors (NCT03588039) | Athenex, Inc. | 2018-10-25 |
| A Phase 1b/2 Study of Rebastinib (DCC-2036) in Combination With Paclitaxel in Patients With Advanced or Metastatic Solid Tumors (NCT03601897) | Deciphera Pharmaceuticals, LLC | 2018-10-25 |
| A Study to Evaluate the Safety and Tolerability of JNJ-67670187 in Healthy Participants (NCT03723746) | Janssen Research & Development, LLC | 2018-10-25 |
| The Safety, Tolerability and Pharmacokinetic Study of Litapiprant Tablets in Healthy Male and Female Subjects (NCT03663686) | Sunshine Lake Pharma Co., Ltd. | 2018-10-25 |
| Safety, Tolerability and Pharmacokinetics of Y-2(Edaravone And Borneol) Sublingual Tablet (NCT03495206) | Yantai YenePharma Co., Ltd. | 2018-10-25 |
| A Study of WXFL10030390 in Patients With Advanced Solid Tumors or Lymphoma (NCT03730142) | Shanghai Jiatan Pharmatech Co., Ltd | 2018-10-25 |
| Non-opioids for Analgesia After Adenotonsillectomy in Children (NCT03618823) | David Chi, MD | 2018-10-25 |
| Single Dose Truvada Study (NCT03719053) | Johns Hopkins University | 2018-10-25 |
| A Study in Healthy Adult Volunteers to Assess the Safety and Pharmacokinetics of an Investigational Imaging Product (NCT03698305) | Astellas Pharma Global Development, Inc. | 2018-10-25 |
| Pembrolizumab in Association With the IMA950/Poly-ICLC for Relapsing Glioblastoma (NCT03665545) | University Hospital, Geneva | 2018-10-25 |
| Dexamethasone, Carfilzomib, & Nivolumab With Pelareorep for Relapsed/Refractory Multiple Myeloma (NCT03605719) | Emory University | 2018-10-24 |
| Clinical Trial to Evaluate Pharmacokinetic Profiles and Safety Between CKD-385 and D935 in Healthy Volunteers (NCT03748212) | Chong Kun Dang Pharmaceutical | 2018-10-24 |
| Venetoclax Added to Fludarabine + Busulfan Prior to Transplant and to Maintenance Therapy for AML, MDS, and MDS/MPN (NCT03613532) | Jacqueline Garcia, MD | 2018-10-24 |
| A Study of ABBV-011 Alone and in Combination With Budigalimab (ABBV-181) in Participants With Relapsed or Refractory Small Cell Lung Cancer (NCT03639194) | AbbVie | 2018-10-24 |
| A Study to Assess the Safety and Tolerability of Different Doses of AG019 Administered Alone or in Combination With Teplizumab in Participants With Recent-onset Diagnosed Type 1 Diabetes (T1D) (NCT03751007) | Precigen Actobio T1D, LLC | 2018-10-24 |
| Mogamulizumab and Pembrolizumab in Treating Patients With Relapsed or Refractory Diffuse Large B Cell Lymphoma (NCT03309878) | National Cancer Institute (NCI) | 2018-10-24 |
| Can Epinephrine Coated Syringe for Subcutaneous Immunotherapy (SCIT) Reduce Large Local Reaction? (NCT03963115) | Mahidol University | 2018-10-24 |
| First in Human Testing of Dose-escalation of SAR440234 in Patients With Acute Myeloid Leukemia, Acute Lymphoid Leukemia and Myelodysplastic Syndrome (NCT03594955) | Sanofi | 2018-10-24 |
| Open-label PET Study With [11C]Osimertinib in Patients With EGFRm NSCLC and Brain Metastases (NCT03463525) | AstraZeneca | 2018-10-24 |
| RPTR-147 in Patients With Selected Solid Tumors and Lymphomas (NCT03815682) | Repertoire Immune Medicines | 2018-10-24 |
| MOv19-BBz CAR T Cells in aFR Expressing Recurrent High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (NCT03585764) | University of Pennsylvania | 2018-10-24 |
| Imaging Study to Compare Effects of Darolutamide and Enzalutamide With Respect to Placebo on the Blood Flow in the Brain in Healthy Male Volunteers. (NCT03704519) | Bayer | 2018-10-23 |
| Regorafenib and Nivolumab in Mismatch Repair (MMR) Refractory Colorectal Cancer (NCT03712943) | H. Lee Moffitt Cancer Center and Research Institute | 2018-10-23 |
| Single-dose and Multiple-dose X842 Phase 1 Study (NCT04293965) | Jiangsu Sinorda Biomedicine Co., Ltd | 2018-10-23 |
| A Study to Evaluate the Pharmacokinetics and Safety of HIP1701 in Healthy Subjects (NCT04087525) | Hanmi Pharmaceutical Company Limited | 2018-10-23 |
| Fibrinogen Concentrate in Isolated Traumatic Brain Injury (NCT03304899) | Leila Dehghani | 2018-10-23 |
| Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation (NCT03721822) | University of Pennsylvania | 2018-10-23 |
| Pharmacokinetic Interaction Between Ibuprofen and Acetaminophen, Tablets Administered Individually or in Combination (NCT05428306) | Laboratorios Silanes S.A. de C.V. | 2018-10-23 |
| Study of Drug 1 (Enzalutamide) Plus Drug 2 (Relacorilant) for Patients With Prostate Cancer (NCT03674814) | University of Chicago | 2018-10-23 |
| Food Effect Study of D-0502 Tablet in Healthy Volunteers (NCT03810625) | InventisBio Co., Ltd | 2018-10-23 |
| A Study of Mirikizumab in Participants With Plaque Psoriasis (NCT03718884) | Eli Lilly and Company | 2018-10-23 |
| To Evaluate the Pharmacokinetics and Safety of Oral Administration of BR9001 Compared With BR900A in Healthy Subjects (NCT03718611) | Boryung Pharmaceutical Co., Ltd | 2018-10-22 |
| A Study Using fMRI Imaging to Evaluate the Effect of NKTR-181 on Brain Activity in Healthy, Non-physically Dependent Recreational Opioid Users. (NCT03802227) | Nektar Therapeutics | 2018-10-22 |
| Evaluation of Pharmacokinetics, Safety, and Preliminary Efficacy of Isatuximab in Chinese Patients With Relapsed and/or Refractory Multiple Myeloma (NCT03733717) | Sanofi | 2018-10-22 |
| First Time in Humans (FTIH) Study of GSK3368715 in Participants With Solid Tumors and Diffuse Large B-cell Lymphoma (DLBCL) (NCT03666988) | GlaxoSmithKline | 2018-10-22 |
| Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies (NCT03539822) | Anwaar Saeed | 2018-10-22 |
| To Evaluate the Therapeutic Equivalence and Safety in Treatment of Scalp Psoriasis (NCT03880357) | Sun Pharmaceutical Industries, Inc. | 2018-10-22 |
| SBRT and Anti-programmed Cell Death Protein 1(Anti-PD-1) in Late Stage or Recurrent Pancreatic Cancer Patients (NCT03716596) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2018-10-22 |
| A Study of RBT-3 in Healthy Volunteers and Volunteers With Stage 3/4 Chronic Kidney Disease (NCT04072432) | Renibus Therapeutics, Inc. | 2018-10-21 |
| Evaluating Efficacy and Safety of Danazol in Severe Hematologic or Pulmonary Disease Related to Telomeropathy (NCT03710356) | Assistance Publique - Hôpitaux de Paris | 2018-10-20 |
| AMPLIFYing NEOepitope-specific VACcine Responses in Progressive Diffuse Glioma (NCT03893903) | German Cancer Research Center | 2018-10-19 |
| Study of CS3006 in Subjects With Locally Advanced or Metastatic Solid Tumors (NCT03736850) | CStone Pharmaceuticals | 2018-10-19 |
| FPT155 in Patients With Advanced Solid Tumors (NCT04074759) | Five Prime Therapeutics, Inc. | 2018-10-18 |
| A Phase 1/2 Trial of Multiple Oral Doses of OPC-167832 for Uncomplicated Pulmonary Tuberculosis (NCT03678688) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2018-10-18 |
| A Study to Evaluate the Relative Bioavailability (BA) and Effect of Food on TAK-831 Tablet Formulations in Healthy Participants (NCT03706469) | Neurocrine Biosciences | 2018-10-18 |
| Study of Alkotinib in Patients With Advanced Non Small Cell Lung Cancer (NCT03607188) | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 2018-10-18 |
| A Study to Assess Safety and Efficacy of Venetoclax in Combination With Gilteritinib in Participants With Relapsed/Refractory Acute Myeloid Leukemia (NCT03625505) | AbbVie | 2018-10-18 |
| FUSCC Refractory TNBC Umbrella (FUTURE) (NCT03805399) | Fudan University | 2018-10-18 |
| CHF6467 SAD and MAD in Patients With Diabetic Foot Ulcer (NCT04077671) | Chiesi Farmaceutici S.p.A. | 2018-10-17 |
| VY-AADC02 for Parkinson's Disease With Motor Fluctuations (RESTORE-1) (NCT03562494) | Neurocrine Biosciences | 2018-10-17 |
| A Study to Evaluate the Safety and Efficacy of JCAR017 in Pediatric Subjects With Relapsed/Refractory (r/r) B-cell Acute Lymphoblastic Leukemia (B-ALL) and B-cell Non-Hodgkin Lymphoma (B-NHL) (NCT03743246) | Celgene | 2018-10-17 |
| Diet, Diabetes and Periodontitis (NCT03407508) | Kristianstad University | 2018-10-17 |
| Phase 1 Study of ONO-7475 With and Without ONO-4538 in Subjects Advanced or Metastatic Solid Tumors (NCT03730337) | Ono Pharmaceutical Co., Ltd. | 2018-10-17 |
| Study of OXB-102 (AXO-Lenti-PD) in Patients With Bilateral, Idiopathic Parkinson's Disease (NCT03720418) | Sio Gene Therapies | 2018-10-17 |
| A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ABP-671 in Healthy Subjects (NCT03906006) | Atom Therapeutics Co., Ltd | 2018-10-17 |
| Study to Evaluate the Safety and Efficacy of a Combination of Favezelimab (MK-4280) and Pembrolizumab (MK-3475) in Participants With Hematologic Malignancies (MK-4280-003) (NCT03598608) | Merck Sharp & Dohme LLC | 2018-10-17 |
| Autologous, Culture-Expanded Mesenchymal Stromal Cells for Degenerative Disc Disease (NCT03461458) | Mayo Clinic | 2018-10-17 |
| Effects of 20,000 EU of Clinical Center Reference Endotoxin (CCRE) Versus Placebo(ENDOHEART) (NCT03623022) | University of North Carolina, Chapel Hill | 2018-10-17 |