| A Safety Study of LY3437943 Given as a Single Injection in Healthy Participants (NCT03841630) | Eli Lilly and Company | 2019-03-13 |
| A Study of Unesbulin (PTC596) in Combination With Dacarbazine in Participants With Advanced Leiomyosarcoma (LMS) (NCT03761095) | PTC Therapeutics | 2019-03-13 |
| Gentuzumab Ozogamicin and Midostaurin Combination With Standard Cytarabine and Danunorubi Midostaurin as a Novel Approach to Treating Patients With Newly Diagnosed FLT-3 Mutated Acute Myeloid Leukemia (NCT03900949) | Uma Borate | 2019-03-13 |
| To Assess the Safety, Immunogenicity and Efficacy of VLPM01 in Healthy, Malaria-Naïve Volunteers (NCT03867331) | VLP Therapeutics | 2019-03-13 |
| Study of ACTR T Cell Product in Combination With Trastuzumab in Subjects With HER2-Positive Advanced Solid Tumor Cancers (NCT03680560) | Cogent Biosciences, Inc. | 2019-03-13 |
| Combination Chemotherapy and TAK-659 as Front-Line Treatment in Treating Patients With High-Risk Diffuse Large B Cell Lymphoma (NCT03742258) | Northwestern University | 2019-03-13 |
| OPEN LABEL, 2-PERIOD STUDY, TO COMPARE BIO-AVAILABILITY OF 2 DIFFERENT FORMULATIONS OF PF-05221304 IN HEALTHY ADULTS (NCT03871439) | Pfizer | 2019-03-13 |
| A Study of Copanlisib and Ibrutinib in Mantle Cell Lymphoma (NCT03877055) | Memorial Sloan Kettering Cancer Center | 2019-03-13 |
| Human CD19 Targeted T Cells Injection Therapy for Relapsed and Refractory CD19-positive Leukemia (NCT03798509) | Hrain Biotechnology Co., Ltd. | 2019-03-13 |
| Safety of GH001 in Healthy Volunteers (NCT04640831) | GH Research Ireland Limited | 2019-03-13 |
| SD-101 and BMS-986178 in Treating Patients With Advanced or Metastatic Solid Malignancies (NCT03831295) | Ronald Levy | 2019-03-13 |
| PRF in Management of Chronic Multiple Oral Ulcers (NCT03878771) | Beni-Suef University | 2019-03-13 |
| Body Compartment Pharmacokinetics of Anti-retroviral Agents That May be Considered for Future On-demand Peri-exposure HIV Prophylaxis Regimens (NCT03976752) | Emory University | 2019-03-13 |
| D-serine Augmentation of Neuroplasticity (NCT03711500) | New York State Psychiatric Institute | 2019-03-13 |
| A Bioequivalence Study Between Fluticasone Salmeterol Xinafoate vs. SERETIDE DISKUS® in Healthy Volunteers With Charcoal Blockade (BREATH-PK250-CC) (NCT03894280) | Respirent Pharmaceuticals Co Ltd. | 2019-03-12 |
| JS001 Combined With Regorafenib in Patients With Advanced Colorectal Cancer (NCT03946917) | Sun Yat-sen University | 2019-03-12 |
| A Single and Multiple Ascending Dose Study in Healthy Subjects to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of KP-1199 (NCT03880487) | Kalyra Pharmaceuticals, Inc. | 2019-03-12 |
| A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB054 in Japanese Participants With Parkinson's Disease (NCT03716570) | Biogen | 2019-03-12 |
| Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma (NCT03696784) | UNC Lineberger Comprehensive Cancer Center | 2019-03-12 |
| Open Label Pharmaco- Magnetic Resonance Spectrography (MRS) Study of Clavulanic Acid (NCT03986762) | Temple University | 2019-03-12 |
| Venetoclax in Combination With BEAM Conditioning Regimen for ASCT in Non-Hodgkin Lymphoma (NCT03713580) | Case Comprehensive Cancer Center | 2019-03-12 |
| Safety and Efficacy of Tenalisib (RP6530) in Combination With Romidepsin in Patients With Relapsed/Refractory T-cell Lymphoma (NCT03770000) | Rhizen Pharmaceuticals SA | 2019-03-12 |
| A Study in People With Depression to Test the Effects of BI 1358894 on Parts of the Brain That Are Involved in Emotions (NCT03854578) | Boehringer Ingelheim | 2019-03-12 |
| A Study to Evaluate Safety, Tolerability and Immune Response in Adolescents Allergic to Peanut After Receiving Intradermal Administration of ASP0892 (ARA-LAMP-vax), a Single Multivalent Peanut (Ara h1, h2, h3) Lysosomal Associated Membrane Protein DNA Plasmid Vaccine (NCT03755713) | Astellas Pharma Global Development, Inc. | 2019-03-12 |
| A Phase I Study of XZP-3621 in Chinese Patients With ALK or ROS1 Rearrangement Non-small Cell Lung Cancer (NCT05055232) | Xuanzhu Biopharmaceutical Co., Ltd. | 2019-03-12 |
| A 2 Part Study to Assess the Relative Bioavailability of Tablet Formulation Compared to Capsule Formulation and the Effect of Food and Taste Assessment on the Tablet Formulation in Healthy Participants (NCT03847987) | Hoffmann-La Roche | 2019-03-12 |
| Pembrolizumab and Induction Chemotherapy in Head and Neck Squamous Cell Carcinoma (PICH Study) (NCT03114280) | Centre Antoine Lacassagne | 2019-03-12 |
| HIPEC After Initial CRS in Patients Who Have Received NACT (NCT03540017) | Northwell Health | 2019-03-12 |
| A Safety, Tolerability and Preliminary Efficacy Evaluation of CC-90011 Given in Combination With Cisplatin and Etoposide in Subjects With First Line, Extensive Stage Small Cell Lung Cancer (NCT03850067) | Celgene | 2019-03-12 |
| A First Time in Human (FTIH) Study of GSK3745417 Administered to Participants With Advanced Solid Tumors (NCT03843359) | GlaxoSmithKline | 2019-03-12 |
| Pembrolizumab in Relapsed or Refractory Extranodal NK/T- Cell Lymphoma, Nasal Type and EBV-associated Diffuse Large B Cell Lymphomas (NCT03586024) | Abramson Cancer Center at Penn Medicine | 2019-03-12 |
| Effects of Random Nicotine Delivery on Smoking Cessation (NCT03674970) | Milton S. Hershey Medical Center | 2019-03-12 |
| DC Vaccine in Colorectal Cancer (NCT03730948) | University of Pennsylvania | 2019-03-12 |
| Title: Evaluation of a Novel PET Radioligand for Phosphodiesterase-4D (PDE4D) (NCT03861000) | National Institute of Mental Health (NIMH) | 2019-03-12 |
| Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia (NCT03850574) | Aptose Biosciences Inc. | 2019-03-11 |
| Stem Cell in Acute Myocardial Infarction (NCT04340609) | PT. Prodia Stem Cell Indonesia | 2019-03-11 |
| Study to Evaluate the Effect of IW-3718 on the Pharmacokinetics of Oral Contraceptive, Levothyroxine, Glyburide, and Digoxin in Healthy Adult Volunteers (NCT03856970) | Ironwood Pharmaceuticals, Inc. | 2019-03-11 |
| CyPep-1 in Cutaneous Warts (NCT03846648) | Centre for Human Drug Research, Netherlands | 2019-03-11 |
| Study to Evaluate the Bioequivalence of Astellas Phama Korea Inc. "Harnal-D" in Healthy Volunteers (NCT03887858) | Chong Kun Dang Pharmaceutical | 2019-03-11 |
| Expansion of a Dengue-1 Live Virus Human Challenge (NCT03869060) | State University of New York - Upstate Medical University | 2019-03-11 |
| Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL) (NCT03666000) | Imugene Limited | 2019-03-11 |
| Study to Evaluate the Bioequivalence of Astellas Phama Korea Inc. "Harnal-D" in Healthy Volunteers After Meal (NCT03887871) | Chong Kun Dang Pharmaceutical | 2019-03-11 |
| CART-EGFRvIII + Pembrolizumab in GBM (NCT03726515) | University of Pennsylvania | 2019-03-11 |
| A Double-Blind Placebo-Control Dose Escalating Study to Evaluate the Safety and Immunogenicity of dmLT by Oral, Sublingual and Intradermal Vaccination in Adults Residing in an Endemic Area (NCT03548064) | National Institute of Allergy and Infectious Diseases (NIAID) | 2019-03-10 |
| Drug-drug Interaction (DDI) Study of Spironolactone (Perpetrator) and Digoxin (Substrate Drug) (NCT03909529) | CMP Development, LLC | 2019-03-10 |
| Study of Ammoxetine Hydrochloride Enteric-coated Tablets in Healthy Subject (NCT03850834) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2019-03-10 |
| A Clinical Study to Investigate the Food Effect on the Pharmacokinetics of ACT-541468 in Healthy Male Subjects (NCT03799978) | Idorsia Pharmaceuticals Ltd. | 2019-03-09 |
| A Study of Safety and Primary Immunogenicity of 9-valent HPV Recombinant Vaccine (NCT03900572) | Shanghai Zerun Biotechnology Co.,Ltd | 2019-03-09 |
| Single Agent and Combined Inhibition After Allogeneic Stem Cell Transplant (NCT02846376) | Hackensack Meridian Health | 2019-03-08 |
| The Study of Drug 601 in Patients With Diabetic Macular Edema (DME) (NCT04151407) | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 2019-03-08 |
| Genetically Engineered Cells (NY-ESO-1 TCR Engineered T Cells and HSCs) After Melphalan Conditioning Regimen in Treating Patients With Recurrent or Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (NCT03691376) | Roswell Park Cancer Institute | 2019-03-08 |
| Safety and Immunogenicity of the Human Cytomegalovirus (CMV) Vaccine (V160) in Healthy Japanese Men (V160-003) (NCT03840174) | Merck Sharp & Dohme LLC | 2019-03-08 |
| Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS) (NCT03783377) | Arrowhead Pharmaceuticals | 2019-03-08 |
| Study of WP1220 for the Treatment of Adult Subjects With Cutaneous T-Cell Lymphoma (CTCL) (NCT04702503) | Moleculin Biotech, Inc. | 2019-03-08 |
| A Phase Ib/II Study Investigating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With CHOP or CHP-Polatuzumab Vedotin in Participants With B-Cell Non-Hodgkin Lymphoma (NCT03677141) | Hoffmann-La Roche | 2019-03-08 |
| A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of TAK-954 in Healthy Adult Participants (NCT03870555) | Millennium Pharmaceuticals, Inc. | 2019-03-08 |
| Lung Ultrasound for Predicting Outcome of Weaning From Mechanical Ventilation (NCT03880864) | Ain Shams University | 2019-03-07 |
| Dose, Safety, Tolerability, and Immunogenicity of an HIV-1 Vaccine, VRC-HIVRGP096-00-VP, With Alum in Healthy Adults (NCT03783130) | National Institute of Allergy and Infectious Diseases (NIAID) | 2019-03-07 |
| A Study of TAK-951 in Healthy Adults (NCT05567393) | Takeda | 2019-03-07 |
| PK/PD Study of YZJ-1139 (NCT06685341) | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. | 2019-03-07 |
| Durvalumab and Tremelimumab for Pediatric Malignancies (NCT03837899) | AstraZeneca | 2019-03-07 |
| Tinostamustine and Nivolumab in Advanced Melanoma (NCT03903458) | Markus Joerger | 2019-03-07 |
| Multiple Ascending Dose Study in Healthy Subjects (NCT03879278) | Proclara Biosciences, Inc. | 2019-03-06 |
| The Tolerability and Pharmacokinetics Study of HEC110114 Tablets in Healthy Adult Subjects (NCT03903081) | Sunshine Lake Pharma Co., Ltd. | 2019-03-06 |
| Study to Evaluate Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene (NCT03780257) | ProQR Therapeutics | 2019-03-06 |
| Acute Ischemic Stroke Interventional Study (NCT03803007) | Acticor Biotech | 2019-03-06 |
| The Effect of Traditional Chinese Medicine on Benign Prostatic Hyperplasia (NCT03829904) | Taipei Veterans General Hospital, Taiwan | 2019-03-06 |
| Intranasal Ketamine and Midazolam Mixture for Procedural Sedation in Children With Mental Disabilities: (NCT03860831) | Ain Shams University | 2019-03-06 |
| A Phase I/II Study Evaluating Temferon in Multiple Myeloma Patients With Early Relapse After Front Line Therapy (TEM-MM) (NCT03875495) | Genenta Science | 2019-03-06 |
| A Study of Nivolumab and Intrapleural Talimogene Laherparepvec for Malignant Pleural Effusion (NCT03597009) | UNC Lineberger Comprehensive Cancer Center | 2019-03-06 |
| A Study of CBP-1008 in Patients With Advanced Solid Tumor (NCT04740398) | Coherent Biopharma (Suzhou) Co., Ltd. | 2019-03-06 |
| A Study to Assess the Safety, Tolerability, and Efficacy of BIVV003 for Autologous Hematopoietic Stem Cell Transplantation in Patients With Severe Sickle Cell Disease (NCT03653247) | Sangamo Therapeutics | 2019-03-06 |
| A Study to Test How Different Doses of BI 685509 Are Tolerated in Patients With Liver Problems (NCT03842761) | Boehringer Ingelheim | 2019-03-06 |
| REACTION (Radiation Enhanced Assessment of Combination Therapies in Immuno-ONcology) - Nivolumab or Nivolumab in Combination With Other Immuno-oncology (IO) Agents After Targeted Systemic Radiation in Patients With Advanced Esophagogastric Cancer (NCT03610711) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2019-03-06 |
| Niraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line Chemotherapy (NCT03830918) | Jonsson Comprehensive Cancer Center | 2019-03-06 |
| Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer (NCT03546829) | Abramson Cancer Center at Penn Medicine | 2019-03-05 |
| Targeted Stem Cells Expressing TRAIL as a Therapy for Lung Cancer (NCT03298763) | University College, London | 2019-03-05 |
| Single-dose Incremental Intravenous Injection of SY-007 in Healthy Subjects (NCT04111523) | Suzhou Yabao Pharmaceutical R&D Co., Ltd. | 2019-03-05 |
| Pharmacokinetic Study of CVT-301 (Levodopa Inhalation Powder) (NCT03887884) | Acorda Therapeutics | 2019-03-05 |
| Dexmedetomidine Versus Nalbuphine in Prevention of Emergence Agitation Following Adenotonsillectomy in Pediatrics (NCT04058899) | Ain Shams University | 2019-03-05 |
| Umbilical Cord Blood Transfusion in Progeria Syndrome (NCT03871972) | Bundang CHA Hospital | 2019-03-05 |
| TAK-659 and Paclitaxel in Treating Patients With Advanced Solid Tumors (NCT03756818) | M.D. Anderson Cancer Center | 2019-03-05 |
| A Study of E7386 in Participants With Advanced Solid Tumor Including Colorectal Cancer (CRC) (NCT03833700) | Eisai Co., Ltd. | 2019-03-05 |
| Dry Pleurodesis With Talcum and Afatinib is Used to Treat Patients With Non-Small Cell Lung Carcinoma (NCT03827070) | Center Trials & Treatment Europe | 2019-03-05 |
| Generation of Biological Samples Positive to Hydrochlorothiazide for Anti-doping Control (NCT04197622) | Parc de Salut Mar | 2019-03-05 |
| Subcutaneous Doses of CM-101 as a Treatment for Medical Conditions Involving Inflammatory and Fibrotic Mechanisms in Healthy Male Subjects (NCT06037577) | ChemomAb Ltd. | 2019-03-05 |
| Nanoliposomal Irinotecan (Nal-IRI, ONIVYDE®) in Combination With TAS-102 (LONSURF®) in Refractory Solid Tumors (NCT03810742) | PharmaEngine | 2019-03-05 |
| High Dose Ascorbic Acid for Plasma Cell Disorders (NCT03602235) | Christopher Strouse | 2019-03-05 |
| A Study Evaluating Temferon in Patients With Glioblastoma & Unmethylated MGMT (NCT03866109) | Genenta Science | 2019-03-05 |
| AMG 404 in Patients With Advanced Solid Tumors (NCT03853109) | Amgen | 2019-03-05 |
| Study of TG-1801 in Subjects With B-Cell Lymphoma (NCT03804996) | TG Therapeutics, Inc. | 2019-03-05 |
| Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine (NCT03860233) | Vivek Jain | 2019-03-04 |
| Topical rVA576 for Treatment of Atopic Keratoconjunctivitis (NCT04037891) | AKARI Therapeutics | 2019-03-04 |
| Interaction Between Omeprazole and Gliclazide in CYP2C19 Normal/ Ultrarapid Metabolisers (NCT04198948) | University of Sarajevo | 2019-03-04 |
| Bioavailability Study of Two Formulations of Sarpogrelate HCl 300mg Tablets Under Fasting Conditions (NCT03947489) | Daewoong Pharmaceutical Co. LTD. | 2019-03-04 |
| Ipatasertib in Combination With Carboplatin, Carboplatin/Paclitaxel, or Capecitabine/Atezolizumab in Treating Patients With Metastatic Triple Negative Breast Cancer (NCT03853707) | City of Hope Medical Center | 2019-03-04 |
| Bioavailability Study of Two Formulations of Sarpogrelate HCl 300mg Tablets Under Fed Conditions (NCT03947528) | Daewoong Pharmaceutical Co. LTD. | 2019-03-04 |
| Phase Ib/II Study of Carboplatin + M6620 + Avelumab in PARPi-resistant Ovarian Cancer (NCT03704467) | EMD Serono Research & Development Institute, Inc. | 2019-03-04 |
| Assessment of AMG 420 in Subjects With Relapsed and/or Refractory Multiple Myeloma (NCT03836053) | Amgen | 2019-03-04 |
| Evaluate the Infectivity Equivalence of Current and New Lots of Plasmodium Falciparum Strain NF54 (NCT03882528) | U.S. Army Medical Research and Development Command | 2019-03-04 |