| A Phase Ib/II Study of ATG-022 Plus Pembrolizumab With/Without Chemotherapy in Participants With Claudin (CLDN) 18.2-positive, HER2-negative, Unresectable or Metastatic Gastric or Gastroesophageal Junction AdenocarcinomaUnresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (NCT07327229) | Antengene Biologics Limited | 2026-02-27 |
| A Clinical Trial on the Efficacy and Safety of TQB6411 for Injection (NCT07367529) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2026-02-26 |
| A Study to Evaluate the Safety and Pharmacokinetics of AD-116 and AD-1161 in Healthy Adult Male Subjects (NCT07444385) | Addpharma Inc. | 2026-02-26 |
| [18F]FTT Positron Emission Tomography for the Measurement of PARP Tumor Expression in Patients With Metastatic Breast Cancer (NCT06502691) | University of Washington | 2026-02-26 |
| A Phase 1 Study of the Safety and How the Body Processes ABBV-722 and Upadacitinib After Multiple Oral Doses in Healthy Adult Participants (NCT07425899) | AbbVie | 2026-02-26 |
| Molecular Imaging of Fibroblast Activation Protein Expression Using Labeled Technetium-99m HYNIC-FAPI (NCT07457541) | Tomsk National Research Medical Center of the Russian Academy of Sciences | 2026-02-26 |
| To Evaluate the Tolerability and Pharmacokinetics of TQB3142 for Injection in Patients With Advanced Malignant Tumors (NCT07338838) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2026-02-26 |
| Quercetin in Patients With XIAP (X-linked Inhibitor of Apoptosis) Deficiency (NCT07433621) | Children's Hospital Medical Center, Cincinnati | 2026-02-26 |
| Efficacy Safety Study of Gene Therapy for Sickle Cell DiseaseSCD Using Autologous CD34+ Cells Transduced ex Vivo, Carrying a Corrected Globin Gene and a Silencing RNA. (NCT07432867) | Assistance Publique - Hôpitaux de Paris | 2026-02-25 |
| The Role of Glucagon in Glucose Metabolism in Humans With and Without Bariatric Surgery (NCT07212868) | The University of Texas Health Science Center at San Antonio | 2026-02-25 |
| A Study of ORX489 in Healthy Adult Participants, Aged 18 to 60 Years (NCT07413666) | Centessa Pharmaceuticals (UK) Limited | 2026-02-25 |
| Study of the Kinesin Oral Molecular Degrader BBI-940 in Subjects With Advanced or Metastatic Breast Cancer (NCT07408089) | Boundless Bio, Inc. | 2026-02-25 |
| A Study of ENX-104 in Healthy Participants (NCT07472361) | Engrail Therapeutics INC | 2026-02-25 |
| Study to Evaluate if Exposure to Drug is Impacted in Participants With Renal Insufficiency (NCT07385547) | Sun Pharmaceutical Industries Limited | 2026-02-25 |
| Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-272 in Healthy Participants (NCT07437105) | Vertex Pharmaceuticals Incorporated | 2026-02-25 |
| Phase 1/2 Study of a Plant-Based Seasonal Recombinant Trivalent VLP Influenza Vaccine (NCT07291635) | Aramis Biotechnologies Inc. | 2026-02-25 |
| Understanding the Health Effect of a Bioactive Peptide From Egg: A Pilot Study (NCT06555393) | University of Alberta | 2026-02-25 |
| Zoledronic Acid Treatment in Patients With Congenital Dyserythropoietic Anemia (NCT07471516) | Institute of Hematology & Blood Diseases Hospital, China | 2026-02-25 |
| A Study to See How Safe a New Medicine (NNC6989-0001) is in Healthy People Living With Overweight or Obesity (NCT07437079) | Novo Nordisk A/S | 2026-02-24 |
| A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics With AZD0780 Following Repeated Dose Administration in Healthy Adults With Elevated LDL-C Levels (NCT07423598) | AstraZeneca | 2026-02-24 |
| A Study of BI 3810944 in Patients With Advanced Cancer (NCT07224425) | Boehringer Ingelheim | 2026-02-24 |
| Single-ascending Dose Study of HEC-151 Injection (NCT07376200) | Sunshine Lake Pharma Co., Ltd. | 2026-02-24 |
| A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types (NCT07503808) | IDEAYA Biosciences | 2026-02-24 |
| Trial of ONC-PluReceptor NK Cells With Epcoritamab and Tafasitamab for Patients With Recurrent or Refractory B-cell Non-Hodgkin Lymphoma (NCT07283679) | M.D. Anderson Cancer Center | 2026-02-24 |
| A Phase 1 Open-label Study to Evaluate Safety in Healthy Participants and Participants With Autoimmune Diseases (NCT07284797) | Xencor, Inc. | 2026-02-24 |
| Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal Tumors (NCT07095517) | Massachusetts General Hospital | 2026-02-24 |
| A Study to Evaluate Safety, PK and Efficacy of GH55 in Combination With GH21 in Patients With Solid Tumors (NCT07446725) | Suzhou Genhouse Bio Co., Ltd. | 2026-02-24 |
| Effect of a Daily Supplement on Plasma PAI-1 Levels (NCT07469475) | University of California, Los Angeles | 2026-02-24 |
| A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function (NCT07426380) | Eli Lilly and Company | 2026-02-24 |
| Momelotinib During and After HCT in Myelofibrosis (NCT07104799) | Massachusetts General Hospital | 2026-02-23 |
| PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia (NCT07101640) | Duke University | 2026-02-23 |
| 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors (NCT07189871) | Radiopharm Theranostics, Ltd | 2026-02-23 |
| First-in-human Study of Orally Administered KT-579 in Healthy Adult Participants (NCT07412288) | Kymera Therapeutics, Inc. | 2026-02-23 |
| Nalmefene Implant in Healthy Subjects (NCT07325279) | ReacX Pharmaceuticals, Inc. | 2026-02-23 |
| Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC (NCT06681220) | VA Office of Research and Development | 2026-02-23 |
| A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) (NCT07148089) | Solid Biosciences Inc. | 2026-02-23 |
| A Clinical Trial to Compare and Evaluate Evaluate the Pharmacokinetics and Safety of CKD-846 (NCT07404735) | Chong Kun Dang Pharmaceutical | 2026-02-23 |
| Effects of Melatonin on Excessive Crying in Neonates. A Randomized Controlled Clinical Trial. (NCT07442162) | Al-Hadba university | 2026-02-23 |
| ADCX-020 for the Treatment of Patients With Locally Advanced or Metastatic Cancers (NCT07238075) | Adcytherix SAS | 2026-02-23 |
| A Study Testing Topical Pain-Relieving Herbal Plasters in People Who Are Using Opioids for Their Pain (NCT07447856) | Memorial Sloan Kettering Cancer Center | 2026-02-23 |
| Gymnastics and Multicomponent Training Intervention in Community-dwelling Older Adults (NCT07766954) | Federal University of the Valleys of Jequitinhonha and Mucuri | 2026-02-20 |
| Safety and Feasibility of Intranasal Insulin in Patients With Spinal Cord Injury (NCT07384052) | HealthPartners Institute | 2026-02-20 |
| Peri-operative Treatment of Resectable Gastroesophageal Cancer Using Bemarituzumab (BEMA) Plus Perioperative Treatment (NCT06978062) | European Organisation for Research and Treatment of Cancer - EORTC | 2026-02-20 |
| Safety and Efficacy Study of Human Umbilical Cord Mesenchymal Stem Cells in Preventing Arteriovenous Fistula Stenosis in Patients With End-Stage Diabetic Kidney Disease (NCT07452822) | Jiangsu Topcel-KH Pharmaceutical Co., Ltd. | 2026-02-20 |
| Immune Tolerance Induction After Liver Transplantation (NCT07269041) | University of California, Los Angeles | 2026-02-20 |
| Safety, Tolerability and Preliminary Efficacy of NEUK203-13 in Refractory Neuroendocrine Tumor Patients (NCT07366658) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2026-02-20 |
| TSL2109 Capsules in Advanced Solid Tumor Patients: Safety, Tolerability, PK and Preliminary Efficacy (NCT07514065) | Tasly Pharmaceutical Group Co., Ltd | 2026-02-20 |
| A Study on IB-001 Dose Response and Tolerability in Healthy Adults and Those With Chronic Hepatitis B (NCT07389044) | IntegerBio | 2026-02-20 |
| Effect of Local Use of Vitamin D on the Rate of Canine Distillization: a Split Mouth Randomized Control Trial (NCT07479290) | Foundation University Islamabad | 2026-02-20 |
| [18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications (NCT07432633) | Blue Earth Diagnostics | 2026-02-19 |
| A Clinical Study of MK-1045 in People With Lupus or Rheumatoid Arthritis (MK-1045-004) (NCT07363590) | Merck Sharp & Dohme LLC | 2026-02-19 |
| Testing the Addition of Pedmark to Cisplatin Chemotherapy for Reducing Drug-Induced Ear Damage in Men With Stage II-III Metastatic Testicular Germ Cell Tumors (NCT07218913) | City of Hope Medical Center | 2026-02-19 |
| Personalized Antisense Oligonucleotide Therapy for Participants With TARDBP ALS (NCT07743268) | n-Lorem Foundation | 2026-02-19 |
| Sense4Safety Intervention (NCT07220668) | University of Pennsylvania | 2026-02-19 |
| A Study to Evaluate the Effect of BMS-986278 on Cardiac Repolarization in Healthy Participants (NCT07422298) | Bristol-Myers Squibb | 2026-02-19 |
| SB-4826 in Adult Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphomas (NCT07222631) | University of California, San Diego | 2026-02-18 |
| UKK-0018 as an Immunotherapeutic for Treatment of Peanut Allergies (NCT07349212) | Ukko Inc | 2026-02-18 |
| Evaluation of MTX-463 Administered Subcutaneously in Healthy Adult Males (NCT07450521) | Mediar Therapeutics | 2026-02-18 |
| Phase 1 Study of JV-394 Autologous Anti-CD94 CAR T for r/r CD94+ T/NK Cell Neoplasms (NCT07382817) | M.D. Anderson Cancer Center | 2026-02-18 |
| Tolerance Results and Immune Mechanisms in Cow´s Milk and/or Hen´s Egg Allergic Children Following Natural Evolution or Oral Immunotherapy (NCT07419243) | Fundación de Investigación Biomédica - Hospital Universitario de La Princesa | 2026-02-18 |
| Safety and Tolerability of IRL757 in Participants With Parkinson's Disease and Apathy (NCT07461220) | Integrative Research Laboratories AB | 2026-02-18 |
| A First in Human Study of the Safety, Tolerability, and the Physiologically Based Pharmacokinetics of XFB19 in Healthy Adult Volunteers. (NCT05361733) | Xfibra, Inc. | 2026-02-17 |
| A Study of ELA026 in Participants With Relapsed/Refractory (R/R) T/NK Cell Malignancies (TCMs) (NCT07465835) | Electra Therapeutics Inc. | 2026-02-17 |
| A Study of LAD106 in Healthy Adult Participants (NCT07471932) | Almirall, S.A. | 2026-02-17 |
| CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors (NCT07335497) | Crescent Biopharma, Inc. | 2026-02-17 |
| Safety and Efficacy of Tegavivint in Patients With Metastatic Colorectal Carcinoma (NCT07463599) | HonorHealth Research Institute | 2026-02-17 |
| ABY-029 Glioma Trial (NCT07063693) | Dartmouth-Hitchcock Medical Center | 2026-02-17 |
| First-in-human (FIH) Trial of GEN3018 in Relapsed or Refractory (R/R) Acute Myeloid Leukemia (AML) or Higher-risk Myelodysplastic Syndrome (HR-MDS) (NCT07384715) | Genmab | 2026-02-16 |
| Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma (NCT07214298) | Roswell Park Cancer Institute | 2026-02-16 |
| A Study to Investigate the Concentrations of Zibotentan and Dapagliflozin in Blood When Given With and Without Food (NCT07404137) | AstraZeneca | 2026-02-16 |
| Inhaled RB042 in Healthy Adult Volunteers, Healthy Adult Smokers and Patients With Chronic Obstructive Pulmonary Disease (NCT07285122) | Atisama Therapeutics | 2026-02-16 |
| ATRA and SDK002 in Combination With Chemotherapy and Anti-PD-1 Inhibitor in Patients With Advanced Pancreatic Ductal Adenocarcinoma. (NCT07348107) | Daniel Breadner | 2026-02-15 |
| N-803 in Combination With Pembrolizumab and Enfortumab Vedotin for Treatment of Urothelial Cancer (NCT07217496) | Vadim S Koshkin | 2026-02-15 |
| Affordable Made-in-India Microspheres for Liver Cancer Therapy (NCT07436988) | Post Graduate Institute of Medical Education and Research, Chandigarh | 2026-02-15 |
| A Clinical Study on the Efficacy and Safety of Ivarmacitinib in Preventing aGVHD After HLA-matched Transplantation (NCT07381114) | Institute of Hematology & Blood Diseases Hospital, China | 2026-02-14 |
| Study of Safety and Efficacy of HS-10542 in Patients With Paroxysmal Nocturnal Hemoglobinuria (NCT07470762) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2026-02-14 |
| A Phase 1 Study of ISM4808 in Healthy Adult Subjects (NCT07415304) | TaiGen Biotechnology Co., Ltd. | 2026-02-13 |
| Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors (NCT07360314) | EMD Serono Research & Development Institute, Inc. | 2026-02-13 |
| Trial of THEO-260 (Administered Via Intraperitoneal Route) in Ovarian Cancer Patients (NCT07211659) | Theolytics Limited | 2026-02-13 |
| Safety and Proof-of-Concept Study of RPT1G in Adults With Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndromes (NCT07107126) | Remedy Plan, Inc. | 2026-02-13 |
| A First in Human Study of PLT012 in Participants With Solid Tumor Cancers (NCT07337525) | Pilatus Biosciences Inc | 2026-02-13 |
| Evaluation of the Excretion of Suzetrigine Into Breast Milk in Healthy Lactating Female Participants (NCT07378865) | Vertex Pharmaceuticals Incorporated | 2026-02-13 |
| Modulation of the Bone Immune Microenvironment Following Cabozantinib Treatment of Bone Metastatic Clear Cell Renal Cell Carcinoma: Proof of Concept Study (NCT07187869) | M.D. Anderson Cancer Center | 2026-02-12 |
| Study of BPI-572270 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS (NCT07435038) | Betta Pharmaceuticals Co., Ltd. | 2026-02-12 |
| Adoptive T Cell Therapy With DC/AML Fusion Vaccine Plus Decitabine and Venetoclax in AML (NCT07374029) | David Avigan | 2026-02-12 |
| CAR-NK Cells (CL-NK-003) in Pancreatic Cancer (NCT07425483) | Changhai Hospital | 2026-02-12 |
| Phase 1b Trial of BMS-986504 in Combination With Olaparib in Patients With MTAP Loss (NCT07382544) | M.D. Anderson Cancer Center | 2026-02-12 |
| Clinical Trial Evaluating TQB6411 Injection in Participant s With Esophageal Cancer (NCT07367516) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2026-02-12 |
| MRG003 Plus HX008 as First-Line Treatment for EGFR-Positive Locally Advanced or Metastatic Penile Squamous Cell Carcinoma (NCT07054307) | Jiyan Liu | 2026-02-12 |
| Safety and Immunogenicity of Innocell Autologous Cellular Immunotherapy for Recurrent Epithelial Ovarian Cancer (NCT06366490) | PhotonPharma, Inc. | 2026-02-12 |
| Clinical Trial of the Safety and Tolerability of MMH-522 in Healthy Volunteers (NCT07754279) | Materia Medica Holding | 2026-02-12 |
| To Evaluate the Safety, Pharmacokinetics, and Efficacy of GB10 Intravitreal Injection in Patients With Neovascular Age-related Macular Degeneration (nAMD) (NCT07406438) | Shenzhen Kexing Pharmaceutical Co., Ltd. | 2026-02-12 |
| A Study of ABBV-295 Subcutaneous Injections to Assess Pharmacokinetics and Adverse Events in Healthy Adult Women Participants With Overweight or Obesity Taking Oral Contraceptives (NCT07414784) | AbbVie | 2026-02-11 |
| 5-Azacitidine Plus PD-1/PD-L1 Inhibitor With PD-1/PD-L1 Refractory Tumors (NCT07404332) | Mohammed Milhem | 2026-02-11 |
| A Study of Absorption, Distribution, Metabolism and Excretion (ADME) of [14C]AZD4144 (NCT07518459) | AstraZeneca | 2026-02-11 |
| A Phase Ib/II Study of 7MW3711 Combined With JS207 in Advanced Solid Tumors (NCT07466160) | Mabwell (Shanghai) Bioscience Co., Ltd. | 2026-02-11 |
| A Study to Assess How the Body Absorbs ABBV-8736 Subcutaneous Injections Relative to Intravenous Injections in Adult Healthy Volunteers (NCT07413133) | AbbVie | 2026-02-11 |
| Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors (NCT06625190) | University of Florida | 2026-02-11 |
| A First-in-Human Safety and Efficacy Study of ALN-CFB, a Small Interfering RNA (siRNA) Targeting Complement Factor B, in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria With Persistent Anemia on a C5 Inhibitor (NCT07187401) | Regeneron Pharmaceuticals | 2026-02-11 |
| MDMA-Assisted Therapy for Mental Healthcare Providers (NCT07102576) | Rachel Yehuda | 2026-02-11 |