| A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-927 With ABBV-368, Budigalimab (ABBV-181) and/or Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors (NCT03893955) | AbbVie | 2019-05-21 |
| A Study to Assess the Relative Bioavailability of Gilteritinib Following a Single Dose of Gilteritinib Mini-tablet Oral Suspension and Gilteritinib Mini-tablets Compared to a Single Dose of Gilteritinib Tablet in Healthy Subjects (NCT03964038) | Astellas Pharma Global Development, Inc. | 2019-05-21 |
| A Bioequivalence Study Between Fluticasone Propionate 100 mcg and Salmeterol Xinafoate 50 mcg Inhalation Powder/Respirent Pharmaceuticals vs. ADVAIR DISKUS® 100/50 Inhalation Powder/GSK in Healthy Volunteers (NCT03975166) | Respirent Pharmaceuticals Co Ltd. | 2019-05-21 |
| Bioequivalence Study of Trifluridine and Tipiracil Tablets in Colorectal Cancer Patients (NCT03974594) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2019-05-21 |
| Boost to Brittle Bones - Stem Cell Transplantation for Treatment of Brittle Bones (NCT04623606) | Christian Medical College, Vellore, India | 2019-05-20 |
| Study on the Effects of Different Premedication for LISA on Stress and Cerebral Tissue Oxygenation in Preterm Infants (NCT03718507) | ASST Fatebenefratelli Sacco | 2019-05-20 |
| Phase 1 Study of Oral QPX2015 in Healthy Adult Subjects (NCT03939429) | Qpex Biopharma, Inc. | 2019-05-20 |
| A Dose Escalation and Expansion Study of TRX518 in Combination With Cyclophosphamide Plus Avelumab in Advanced Solid Tumors (NCT03861403) | Leap Therapeutics, Inc. | 2019-05-20 |
| Pgp Transporter and CNS Biodistribution of Ondansetron in Healthy Volunteers (NCT03809234) | Washington University School of Medicine | 2019-05-20 |
| Pharmacokinetics and Safety of SAR441236 (NCT03705169) | National Institute of Allergy and Infectious Diseases (NIAID) | 2019-05-20 |
| UCDCC#272: IL-2, Radiotherapy, and Pembrolizumab in Patients Refractory to Checkpoint Blockade (NCT03474497) | Megan Daly, MD | 2019-05-20 |
| PRGN-3006 Adoptive Cellular Therapy for CD33-Positive Relapsed or Refractory AML, MRD Positive AML or Higher Risk MDS (NCT03927261) | Precigen, Inc | 2019-05-20 |
| Study of CB-839 (Telaglenastat) in Combination With Talazoparib in Patients With Solid Tumors (NCT03875313) | Calithera Biosciences, Inc | 2019-05-20 |
| Hyperthermia and Olaparib in Treating Breast Cancer Patients With Chest Wall Recurrences (NCT03955640) | Thomas Jefferson University | 2019-05-20 |
| A Safety and Preliminary Efficacy Study of CC-99282, Alone and in Combination With Anti-lymphoma Agents in Participants With Relapsed or Refractory Non-Hodgkin Lymphomas (R/R NHL) (NCT03930953) | Celgene | 2019-05-20 |
| Nebulized Budesonide Combined With Systemic Corticosteroid in Acute Severe Asthma (NCT04016220) | University of Monastir | 2019-05-20 |
| A Phase I Study of TQB3616 on Tolerance and Pharmacokinetics (NCT03850873) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2019-05-20 |
| Safety, Dose Tolerance, Pharmacokinetics, and Pharmacodynamics Study of CPX-POM in Patients With Advanced Solid Tumors (NCT04608045) | CicloMed LLC | 2019-05-19 |
| Safety and Tolerability Study of the VAC∆6 Vaccine in Volunteers Aged 18-40 Years (NCT05762523) | Federal Budgetary Research Institution State Research Center of Virology and Biotechnology "Vector" | 2019-05-18 |
| Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome (NCT03813147) | National Cancer Institute (NCI) | 2019-05-17 |
| A Study of FT 4101 in Overweight/Obese Participants With Non-alcoholic Steatohepatitis (NCT04004325) | Forma Therapeutics, Inc. | 2019-05-17 |
| PD-1 Knockout Anti-MUC1 CAR-T Cells in the Treatment of Advanced Breast Cancer (NCT05812326) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2019-05-17 |
| Wharton´s Jelly Derived Mesenchymal Stromal Cell Repeated Treatment of Adult Patients Diagnosed with Type I Diabetes (NCT03973827) | NextCell Pharma Ab | 2019-05-17 |
| IRX-2, Cyclophosphamide, and Nivolumab in Treating Patients With Recurrent or Metastatic and Refractory Liver Cancer (NCT03655002) | City of Hope Medical Center | 2019-05-17 |
| Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignancies (NCT03881488) | Compass Therapeutics | 2019-05-17 |
| Safety and Efficacy of IMC-C103C as Monotherapy and in Combination With Atezolizumab (NCT03973333) | Immunocore Ltd | 2019-05-17 |
| Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients (NCT03745326) | National Cancer Institute (NCI) | 2019-05-16 |
| A Study to Investigate the Effects of Gastric Acid Suppression by Rabeprazole and BMS-986165 on How Fast and Complete The Drug is Absorbed Into the Body of Healthy Participants (NCT03979248) | Bristol-Myers Squibb | 2019-05-16 |
| A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics and Safety and Tolerability of a Single Oral Dose of Risdiplam Compared to Matched Healthy Participants With Normal Hepatic Function (NCT03920865) | Hoffmann-La Roche | 2019-05-16 |
| A Clinical Trial to Evaluate a Recombinant Staphylococcus Aureus Vaccine (Escherichia Coli) in Healthy Adults (NCT03966040) | Jiangsu Province Centers for Disease Control and Prevention | 2019-05-16 |
| A Study of CCT301-59 CAR T Therapy in Adult Subjects With Recurrent or Refractory Solid Tumors (NCT03960060) | Shanghai PerHum Therapeutics Co., Ltd. | 2019-05-16 |
| Phase 1a Study to Evaluate Immunogenicity of ASV® (NCT03673020) | Agenus Inc. | 2019-05-16 |
| A Safety and Pharmacokinetic Study of AG-881 in Healthy Male Participants Following Administration of a Single Oral Dose of [14C] AG-881 and Concomitant Intravenous Microdose of [13C315N3] AG-881 (NCT03960502) | Agios Pharmaceuticals, Inc. | 2019-05-16 |
| A 28 Day Parallel Group Study to Assess the Effects of RDN-929 (NCT03963973) | Alkermes, Inc. | 2019-05-16 |
| Hyperpolarized Carbon C 13 Pyruvate in Diagnosing Glioma in Patients With Brain Tumors (NCT03830151) | M.D. Anderson Cancer Center | 2019-05-16 |
| The Safety, Efficacy, and Tolerability of Microbial Ecosystem Therapeutic-2 in People With Major Depression and/or Generalized Anxiety Disorder (NCT04052451) | NuBiyota | 2019-05-16 |
| A Study to Compare the Pharmacokinetics of Budesonide Delivered by PT027 Compared With Pulmicort Flexhaler (ELBRUS) (NCT03934333) | AstraZeneca | 2019-05-16 |
| Safety and Pharmacokinetics Study of Linzagolix in Female Subjects With Normal and Impaired Hepatic Function (NCT03962049) | ObsEva SA | 2019-05-15 |
| PD-1(Programmed Death-1) Antibody +GP as First Line Treatment for Triple Negative Breast Cancer(TNBC) Patients (NCT03251313) | Fudan University | 2019-05-15 |
| Study of the Fecal Microbiome in Patients With Parkinson's Disease (NCT03671785) | The University of Texas Health Science Center, Houston | 2019-05-15 |
| Pharmacokinetic Interactions Between Hydronidone and Entecavir Capsules in Healthy Chinese Subjects (NCT04124081) | Beijing Continent Pharmaceutical Co, Ltd. | 2019-05-15 |
| Modified Immune Cells (CD19-CD22 CAR T Cells) in Treating Patients With Recurrent or Refractory CD19 Positive, CD22 Positive Leukemia or Lymphoma (NCT04029038) | M.D. Anderson Cancer Center | 2019-05-15 |
| Safety and Pharmacokinetics of Linzagolix in Female Subjects With Normal and Impaired Renal Function (NCT03961932) | ObsEva SA | 2019-05-15 |
| The Role of HNKs in the Antidepressant Effect of Ketamine (NCT03977675) | Columbia University | 2019-05-15 |
| Safety, Tolerability and Behavioural Effects of Souroubea-Platanus in Healthy Volunteers (NCT03904511) | University of Ottawa | 2019-05-15 |
| Rifaximin in Patients With Monoclonal Gammopathy (NCT03820817) | Emory University | 2019-05-15 |
| Pacritinib in Relapsed/Refractory Lymphoproliferative Disorders (NCT03601819) | University of Michigan Rogel Cancer Center | 2019-05-15 |
| Study of Pembrolizumab With Pemetrexed and Oxaliplatin in Chemo-Refractory Metastatic Colorectal Cancer Patients (NCT03626922) | NSABP Foundation Inc | 2019-05-15 |
| A Study to Evaluate the Effect of Itraconazole on JNJ-56136379 in Healthy Adult Participants (NCT03945539) | Janssen Sciences Ireland UC | 2019-05-15 |
| Immunologic Response to Kansui in Treated HIV+ Individuals: a Dose Escalation Study (NCT02531295) | University of California, San Francisco | 2019-05-15 |
| Tofacitinib Hypothesis-generating, Pilot Study for Corticosteroid-Dependent Sarcoidosis (NCT03793439) | Oregon Health and Science University | 2019-05-15 |
| A Study to Assess the Relative Oral Bioavailability and Food Effect of Single-dose of JNJ-64417184 in Healthy Participants (NCT03952507) | Janssen Research & Development, LLC | 2019-05-15 |
| Talimogene Laherparepvec, Chemotherapy, and Radiation Therapy Before Surgery in Treating Patients With Locally Advanced or Metastatic Rectal Cancer (NCT03300544) | National Cancer Institute (NCI) | 2019-05-14 |
| GEN1046 Safety Trial in Patients With Malignant Solid Tumors (NCT03917381) | Genmab | 2019-05-14 |
| Safety, Tolerability and Efficacy of Regorafenib in Combination With FOLFIRINOX in Patients With Colorectal Cancer (NCT03828799) | Institut du Cancer de Montpellier - Val d'Aurelle | 2019-05-14 |
| A Study to Determine the Bioavailability of Lanadelumab (SHP643) Administered Subcutaneously With the Prefilled Syringe and the Autoinjector in Healthy Adult Volunteer Participants. (NCT03918239) | Shire | 2019-05-14 |
| CBM588, Nivolumab, and Ipilimumab in Treating Patients With Stage IV or Advanced Kidney Cancer (NCT03829111) | City of Hope Medical Center | 2019-05-14 |
| ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors (NCT03686124) | Immatics US, Inc. | 2019-05-14 |
| AZD8186 and Paclitaxel in Advanced Gastric Cancer (NCT04001569) | Seoul National University Bundang Hospital | 2019-05-14 |
| HEC53856 Phase 1 Study - Single and Multiple Oral Dosing in Healthy Volunteers (NCT03886688) | Sunshine Lake Pharma Co., Ltd. | 2019-05-14 |
| Evaluate the Safety, Tolerability, Biodistribution and Anti Tumour Activity of 177LU-OPS201 With Companion Imaging 68Ga-OPS202 PET/CT in Previously Treated Subjects With Locally Advanced or Metastatic Cancers Expressing Somatostatin Receptor 2 (SSTR2) (NCT03773133) | Ipsen | 2019-05-14 |
| Effects of E-Cigarette Flavors on Adults TCORS 2.0 (NCT03635333) | Yale University | 2019-05-14 |
| CPX-351 in Treating Patients With Relapsed or Refractory High Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia (NCT03896269) | M.D. Anderson Cancer Center | 2019-05-14 |
| Pericardial Matrix With Mesenchymal Stem Cells for the Treatment of Patients With Infarcted Myocardial Tissue (NCT03798353) | Fundació Institut Germans Trias i Pujol | 2019-05-13 |
| Buprenorphine Transdermal Patches Pharmacokinetic Study (NCT03975010) | Mundipharma (China) Pharmaceutical Co. Ltd | 2019-05-13 |
| PET Fibrin Imaging of DVT and PE (NCT04022915) | Peter Caravan | 2019-05-13 |
| A Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of BIIB091, a Bruton's Tyrosine Kinase (BTK) Inhibitor, in Healthy Adult Participants (NCT03943056) | Biogen | 2019-05-13 |
| Study to Evaluate OrienX010 in Combination With JS001 in the Treatment of Stage IV (M1c) Liver Metastasis From Melanoma (NCT04206358) | Peking University Cancer Hospital & Institute | 2019-05-13 |
| Double-Blinded, Placebo-Controlled Phase 1b Study for Safety, PK, Efficacy, PD of RO7049665 in Participants With Ulcerative Colitis (UC) (NCT03943550) | Hoffmann-La Roche | 2019-05-13 |
| Extension Study to Study PQ-110-001 (NCT03140969) (NCT03913130) | Laboratoires Thea | 2019-05-13 |
| Vagal Nerve Stimulation for Intestinal Barrier Dysfunction in Healthy Volunteers (NCT04061564) | Queen Mary University of London | 2019-05-13 |
| Sinemet for Spasticity and Function in Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis (NCT03929068) | Washington University School of Medicine | 2019-05-13 |
| The Interaction Between Diabetes and Estradiol on Human Brain Metabolism in Postmenopausal Women (NCT03681691) | Wake Forest University Health Sciences | 2019-05-13 |
| Modulation of Gut Microbiota by Rifaximin in PD Patients (NCT03958708) | Taipei Medical University Shuang Ho Hospital | 2019-05-13 |
| The Alcohol-Pain Connection: Mechanisms and Genetic/Psychological Correlates (NCT03311594) | Syracuse University | 2019-05-12 |
| Pyrotinib, Dalpiciclib(SHR6390) and Endocrine Therapy in Subjects With Dual-receptor Positive(ER+/HER2+) Advanced Breast Cancer (NCT03772353) | Fudan University | 2019-05-12 |
| PK Linearity and Steady State PK of CHF 6532 in Healthy Subjects (NCT03942666) | Chiesi Farmaceutici S.p.A. | 2019-05-10 |
| A Study of the Safety of REN001 in Patients With Primary Mitochondrial Myopathy (NCT03862846) | Reneo Pharma Ltd | 2019-05-10 |
| 177Lu-PSMA-617 and Pembrolizumab in Treating Patients With Metastatic Castration-Resistant Prostate Cancer (NCT03805594) | University of California, San Francisco | 2019-05-10 |
| A Study of the Pharmacokinetic Interaction Between Pirfenidone and BMS-986278 in Healthy Participants (NCT03981094) | Bristol-Myers Squibb | 2019-05-10 |
| A Phase 1 Study of Intravesical VAX014 for Instillation in Subjects With Non-Muscle Invasive Bladder Cancer (NCT03854721) | Vaxiion Therapeutics | 2019-05-10 |
| Towards Predicting the Analgesic Response to Ibuprofen Following Third-molar Extraction (NCT03893175) | University of Pennsylvania | 2019-05-10 |
| Drug-drug Interaction Study Between Edaravone and 2-Aminoethanesulfonic Acid in Compound Edaravone Injection (NCT04218513) | Nanjing Yoko Biomedical Co., Ltd. | 2019-05-10 |
| This Study in Healthy Men and Women Tests Whether BI 409306 Has an Effect on the ECG (Thorough QT Study) (NCT03934203) | Boehringer Ingelheim | 2019-05-09 |
| A Study of TQB2450 Injection and Anlotinib Hydrochloride Capsules to Treat Triple Negative Breast Cancer (TNBC) (NCT03855358) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2019-05-09 |
| Detection of miRNAs in HPA Axis Function in Healthy Subjects (NCT04066647) | Cedars-Sinai Medical Center | 2019-05-09 |
| Phase 1B Study of KSP/QRH Dimer for Detection of Neoplasia in the Esophagus (NCT03852576) | University of Michigan | 2019-05-09 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Food Effect of TNP-2198 Capsules After Single Oral Dose in Healthy Participants (NCT06081699) | TenNor Therapeutics (Suzhou) Limited | 2019-05-09 |
| Safety, Tolerability and Immunogenicity of INO-4500 in Healthy Volunteers (NCT03805984) | Inovio Pharmaceuticals | 2019-05-09 |
| Pharmacokinetics Evaluation of Recombinant Coagulation Factor VIII Injection in Subjects With Hemophilia A. (NCT04060836) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2019-05-08 |
| A Study of the Effects of LY3372689 on the Brain in Healthy Participants (NCT03944031) | Eli Lilly and Company | 2019-05-08 |
| A Safety, Tolerability, and Pharmacokinetic Study of Tucatinib in Healthy Japanese and Caucasian Subjects (NCT03914755) | Seagen Inc. | 2019-05-08 |
| A Study of Bispecific Antibody MCLA-145 in Patients With Advanced or Metastatic Malignancies (NCT03922204) | Merus B.V. | 2019-05-08 |
| Fostamatinib in the Treatment of Chronic Active Antibody Mediated Rejection (NCT03991780) | Imperial College London | 2019-05-08 |
| Atezolizumab Given in Combination With a Personalized Vaccine in Patients With Urothelial Cancer (NCT03359239) | Matthew Galsky | 2019-05-08 |
| A Study of OKI-179 in Patients With Solid Tumors (NCT03931681) | OnKure, Inc. | 2019-05-08 |
| A Study to Evaluate the Effect of Omeprazole on the Pharmacokinetics of BMS-986205 in Healthy Participants (NCT03936374) | Bristol-Myers Squibb | 2019-05-08 |
| A Study of MEDI1191 in Sequential and Concurrent Combination With Durvalumab in Subjects With Advanced Solid Tumors (NCT03946800) | MedImmune LLC | 2019-05-08 |
| A Research Study of How Overdosing of a New Once Weekly Medicine NNC0148-0287 C (Insulin 287) Influences the Blood Sugar Level in People With Type 2 Diabetes (NCT03945656) | Novo Nordisk A/S | 2019-05-07 |
| Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors. (NCT03891953) | Novartis Pharmaceuticals | 2019-05-07 |