| A Study to Assess the Pharmacokinetics of PXL770 After 4 Weeks of Treatment in Subjects With NAFLD (NCT03950882) | Poxel SA | 2019-08-01 |
| Denosumab for Glucocorticoid-treated Children With Rheumatic Disorders (NCT02418273) | Indiana University | 2019-08-01 |
| Safety and Effect Study of SHR0532 (Drug Code) Tablets in Patients With Mild Hypertension (NCT03971929) | Jiangsu HengRui Medicine Co., Ltd. | 2019-07-31 |
| Disulfiram: A Test of Symptom Reduction Among Patients With Previously Treated Lyme Disease (NCT03891667) | Research Foundation for Mental Hygiene, Inc. | 2019-07-31 |
| Evaluate Safety, Tolerability and Pharmacokinetics of HLX22 in Patients With Advanced Solid Tumors Overexpressing HER2 (NCT03916094) | Shanghai Henlius Biotech | 2019-07-31 |
| Study to Test the Safety of Increasing Multiple Doses of BAY2328065 Given by Mouth, How the Drug is Tolerated and Acts in the Human Body of Healthy Male Participants. Alteration of the Study Drug Effects by Another Drug and the Availability of the Drug Given in Different Formulations is Also Tested. (NCT04027192) | Bayer | 2019-07-31 |
| CD4 CAR+ ZFN-modified T Cells in HIV Therapy (NCT03617198) | University of Pennsylvania | 2019-07-31 |
| Treatment of Non-small Cell Lung Cancer With PD-1 Monoclonal Antibody Combined With Donafenib Toluene Sulfonate (NCT04059874) | First Affiliated Hospital of Zhejiang University | 2019-07-31 |
| A Study in Healthy People to Test How Combining BI 1467335 and Tyramine Affects Blood Pressure (NCT03979820) | Boehringer Ingelheim | 2019-07-31 |
| A Study to Evaluate the Safety, Tolerability and Immunogenicity of Tau Targeted Vaccines in Participants With Early Alzheimer's Disease (NCT04445831) | AC Immune SA | 2019-07-31 |
| Fecal Transplant for Ulcerative Colitis (NCT03948919) | University of Minnesota | 2019-07-31 |
| A Study to Assess the Relative Bioavailability of Roxadustat Following a Single Dose of Pediatric Azo Dye-free Tablet Formulation and Pediatric Azo Dye-free Mini-tablet Formulation Compared to a Single Dose of Azo Dye-containing Tablet Formulation in Healthy Adult Subjects (NCT03960489) | Astellas Pharma Global Development, Inc. | 2019-07-31 |
| The Effectiveness of High Resolution Microendoscopy for People Living With HIV (NCT04563754) | Baylor College of Medicine | 2019-07-30 |
| A Phase 1 Study in Patients With HPV16+ Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma (NCT03978689) | Cue Biopharma | 2019-07-30 |
| First-in-human Study of S-588210 (S-488210+S-488211) (NCT04316689) | Shionogi | 2019-07-30 |
| Clinical Efficacy of MOAP Regimen for Relapsed/Refractory cHL as a Rescue Therapy After DP Regimen (NCT04026269) | Han weidong | 2019-07-30 |
| Expanding the Pool in Lung Transplantation (NCT03377478) | Pablo Sanchez | 2019-07-30 |
| Safety, Tolerability, and Immunogenicity of Zika Vaccine mRNA-1893 in Healthy Flavivirus Seropositive and Seronegative Adults (NCT04064905) | ModernaTX, Inc. | 2019-07-30 |
| Phase Ib Study of TNO155 in Combination With Spartalizumab or Ribociclib in Selected Malignancies (NCT04000529) | Novartis Pharmaceuticals | 2019-07-30 |
| Study of Oral Debio 0123 in Combination With Carboplatin in Participants With Advanced Solid Tumors (NCT03968653) | Debiopharm International SA | 2019-07-30 |
| Absorption, Metabolism and Excretion of 14C-olorofim in Man (NCT04039880) | F2G Ltd | 2019-07-30 |
| First-in-Human Dose Expansion Study of XMT-1536 in Cancers Likely to Express NaPi2b (NCT06517485) | Mersana Therapeutics | 2019-07-30 |
| A Study to Assess the Effect of Venetoclax on Ethinyl Estradiol and Levonorgestrel in Female Participants With Different Hematological Malignancies (NCT03557619) | AbbVie | 2019-07-30 |
| ONC-201 Maintenance Therapy in Acute Myeloid Leukemia and Myelodysplastic Syndrome After Stem Cell Transplant (NCT03932643) | University of Nebraska | 2019-07-30 |
| A Phase I Study of SOR-C13 in Patients With Advanced Solid Tumors (NCT03784677) | M.D. Anderson Cancer Center | 2019-07-29 |
| Evaluation and Treatment of Iron Deficiency in Ovarian Cancer Patients (NCT03933813) | University of Wisconsin, Madison | 2019-07-29 |
| Phase 1b Study of CAR2Anti-CEA CAR-T Cell Hepatic Infusions for Pancreatic Carcinoma Patients With CEA+ Liver Metastases (NCT03818165) | Sorrento Therapeutics, Inc. | 2019-07-29 |
| Evaluate Eribulin ORA in Subjects With Solid Tumors (NCT04013217) | Health Hope Pharma | 2019-07-29 |
| A Study of JNJ-64140284 Solid Dose Formulations in Healthy Male Participants (NCT04033458) | Janssen Research & Development, LLC | 2019-07-29 |
| FMT in Cirrhosis and Hepatic Encephalopathy (NCT03796598) | VA Office of Research and Development | 2019-07-29 |
| Intracameral Levofloxacin (0.5%) vs Intracameral Cefuroxime (NCT04212078) | National University of Malaysia | 2019-07-29 |
| A Study to Evaluate Lucitanib in Combination With Nivolumab in Patients With a Solid Tumor (NCT04042116) | Clovis Oncology, Inc. | 2019-07-29 |
| Chemoradiation With Enadenotucirev as a Radiosensitiser in Locally Advanced Rectal Cancer (NCT03916510) | University of Oxford | 2019-07-29 |
| Safety and Efficacy of OT-82 in Participants With Relapsed or Refractory Lymphoma (NCT03921879) | Oncotartis, Inc. | 2019-07-29 |
| A Multiple Ascending Dose Study of Pegozafermin in Participants With Biopsy Confirmed Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) and at High Risk of NASH (NCT04048135) | 89bio, Inc. | 2019-07-29 |
| A Study of TG103 in Chinese Healthy Adult Subjects (NCT03990090) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2019-07-29 |
| Clinical Pharmacokinetics of Mitoxantrone Hydrochloride Liposome Injection in Recurrent/Refractory Lymphoma Subjects (NCT05173545) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2019-07-29 |
| A Study to Evaluate Subcutaneous TAK-079 Added to Standard of Care Regimens in Participants With Newly Diagnosed Multiple Myeloma (NDMM) (NCT03984097) | Takeda | 2019-07-29 |
| A Study of SHR4010 in Patients With Hemodialysis (NCT04099927) | Jiangsu HengRui Medicine Co., Ltd. | 2019-07-28 |
| Phase I Open-label Study of Low-dose Ketamine Infusion Treatment in Levodopa-Induced Dyskinesia in Parkinson's Disease (NCT06021756) | University of Arizona | 2019-07-28 |
| A Drug Interaction Study of Danicopan (NCT04709094) | Alexion Pharmaceuticals, Inc. | 2019-07-28 |
| Clinical Study to Investigate the Pharmacokinetic Profiles and Safety of CKD-333 in Healthy Volunteers (NCT04019743) | Chong Kun Dang Pharmaceutical | 2019-07-28 |
| A Study to Test How Well Different Doses of BI 754132 Are Tolerated in Patients With an Advanced Form of Age-related Macular Degeneration Called Geographic Atrophy (NCT04002310) | Boehringer Ingelheim | 2019-07-26 |
| Study of NGM621 in Participants With Geographic Atrophy (NCT04014777) | NGM Biopharmaceuticals, Inc | 2019-07-26 |
| Drug Interaction Study of MGL-3196 With Clopidogrel (NCT04671069) | Madrigal Pharmaceuticals, Inc. | 2019-07-26 |
| Dronabinol for Pain and Inflammation in Adults Living With Sickle Cell Disease (NCT03978156) | Yale University | 2019-07-26 |
| The Safety, Tolerability, Pharmacokinetics(PK) of SR419 in Healthy Volunteers (NCT04021563) | Shanghai SIMR Biotechnology Co., Ltd. | 2019-07-26 |
| A Study of Giredestrant (GDC-9545) in Postmenopausal Women With Stage I-III Operable, Estrogen Receptor-Positive Breast Cancer (NCT03916744) | Genentech, Inc. | 2019-07-26 |
| First-in-Human Study of JNJ-74699157 in Participants With Tumors Harboring the KRAS G12C Mutation (NCT04006301) | Janssen Research & Development, LLC | 2019-07-26 |
| A Window of Opportunity Trial of Intratumoral Injection of Copaxone® in Patients With Percutaneously Accessible Tumors (NCT03982212) | University of Kansas Medical Center | 2019-07-26 |
| Single Dose Crossover Comparative Bioavailability Study of Two Formulations of Fluconazole 200 mg in Healthy Adult Subjects Under Fasting Conditions (NCT04038008) | Pharmtechnology LLC | 2019-07-26 |
| Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety, of EXPAREL Administered as Sciatic Nerve Block (In Popliteal Fossa), for Postsurgical Analgesia in Subjects Undergoing Bunionectomy (NCT04002089) | Pacira Pharmaceuticals, Inc | 2019-07-26 |
| Safety and Preliminary Efficacy of OBT076 in Recurrent/Metastatic CD205+ Solid Tumors (NCT04064359) | Oxford BioTherapeutics Ltd | 2019-07-25 |
| S-Nitrosylation (SNO) Therapy During Autologous Blood Transfusion (NCT03999229) | James Reynolds | 2019-07-25 |
| Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery (NCT03904862) | Pediatric Brain Tumor Consortium | 2019-07-25 |
| A Study to Investigate the Effects of RIST4721 on the Inflammatory Response in Healthy Male Subjects Using a Blister Model (NCT04105959) | Aristea Therapeutics, Inc. | 2019-07-25 |
| Impact of Nuedexta on Bulbar Physiology and Function in ALS (NCT03883581) | University of Florida | 2019-07-25 |
| A Drug-drug Interaction Trial of Rifampicin Pharmacokinetics Effect on Fluzoparib (NCT04011124) | Jiangsu HengRui Medicine Co., Ltd. | 2019-07-24 |
| Using a Targeted Cancer Vaccine (Galinpepimut-S) With Immunotherapy (Nivolumab) in Mesothelioma (NCT04040231) | Memorial Sloan Kettering Cancer Center | 2019-07-24 |
| A Phase I Open Label Study to Assess PK and Safety of Plant Cannabis Extract (NCT04261166) | Breath of Life International Pharma Ltd | 2019-07-24 |
| Mass Balance Study to Investigate the Absorption, Metabolism and Excretion of [14C]-EYP001a After a Single Oral Dose (NCT04037618) | Enyo Pharma | 2019-07-24 |
| A Clinical Trial to Compare Pharmacokinetics of the "CDFF0318" and "Champix Tab. 1mg" (NCT04631874) | CTC Bio, Inc. | 2019-07-24 |
| Investigate the Safety, Tolerability and Pharmacokinetics of CHF6523 in Healthy and in COPD Subjects (NCT04032535) | Chiesi Farmaceutici S.p.A. | 2019-07-24 |
| A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD6615 in Healthy Subjects (NCT04055168) | AstraZeneca | 2019-07-24 |
| A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 1323495 in the Blood (NCT04011241) | Boehringer Ingelheim | 2019-07-24 |
| [177Lu]-NeoB in Patients With Advanced Solid Tumors and With [68Ga]-neoB Lesion Uptake (NCT03872778) | Advanced Accelerator Applications | 2019-07-24 |
| A Study to Assess the Pharmacokinetics (PK), Pharmacodynamics (PD) and Safety of 2-Week Treatment With Inhaled AZD7594 in Adolescents (12 to 17 Years) With Asthma (NCT03976869) | AstraZeneca | 2019-07-24 |
| Retinal Effects of Balance Goggles System in Glaucoma Balance Goggles System (BGS) in Patients With Glaucoma (NCT04035239) | Stanford University | 2019-07-23 |
| Study Investigating the Safety and Tolerability of Lu AF88434 in Healthy Young Men (NCT04082325) | H. Lundbeck A/S | 2019-07-23 |
| Study to Evaluate DNL151 in Subjects With Parkinson's Disease (NCT04056689) | Biogen | 2019-07-23 |
| Two-Part, Phase Ib/II, Open Label, Single-Arm, Multi-center Study to Evaluate the Safety and Efficacy of Varlitinib in Combination With Weekly Paclitaxel in EGFR/HER2 Co-expressing Advanced or Metastatic Gastric Cancer Patients (NCT05400915) | Yonsei University | 2019-07-23 |
| Acute Effects of the Prostaglandin (Alprostadil) on Cerebral and Pulmonary Flow (NCT04054115) | The Hospital for Sick Children | 2019-07-23 |
| Immunotherapy of Advanced Hepatitis B Related Hepatocellular Carcinoma With γδT Cells (NCT04032392) | Beijing 302 Hospital | 2019-07-23 |
| 4th Generation Chimeric Antigen Receptor T Cells Targeting Glypican-3 (NCT03980288) | Zhejiang University | 2019-07-23 |
| Evaluate the Safety and Feasibility of Allogeneic Mesenchymal Stem Cells in Patients With Multiple Sclerosis (NCT06360861) | Tehran University of Medical Sciences | 2019-07-23 |
| Neoantigen DNA Vaccine Alone vs. Neoantigen DNA Vaccine Plus Durvalumab in Triple Negative Breast Cancer Patients Following Standard of Care Therapy (NCT03199040) | Washington University School of Medicine | 2019-07-23 |
| Safety and Efficacy of Genolimzumab (GB226) in Combination With Fruquintinib (NCT03976856) | Genor Biopharma Co., Ltd. | 2019-07-23 |
| Single Dose Crossover Study to Compare the Respiratory Drive After Administration of Belbuca, Oxycodone and Placebo. (NCT03996694) | BioDelivery Sciences International | 2019-07-23 |
| Dose-Ranging Study of ST-920, an AAV2/6 Human Alpha Galactosidase A Gene Therapy in Subjects With Fabry Disease (STAAR) (NCT04046224) | Sangamo Therapeutics | 2019-07-23 |
| Efficacy and Safety of AD-MSCs Plus Calpocitriol Ointment in Patients With Moderate to Severe Psoriasis (NCT03392311) | Guangdong Provincial Hospital of Traditional Chinese Medicine | 2019-07-23 |
| A Study of the C3 Complement Inhibitor AMY-101 in Adults With Gingivitis (NCT03694444) | Amyndas Pharmaceuticals S.A. | 2019-07-22 |
| Phase 1b Study to Evaluate ATP128, VSV-GP128 and BI 754091, in Patients With Stage IV Colorectal Cancer (NCT04046445) | Amal Therapeutics | 2019-07-22 |
| Effects of BMS-986256 at Steady State on the Single Dose Pharmacokinetics of Mycophenolate Mofetil (NCT04039373) | Bristol-Myers Squibb | 2019-07-22 |
| A Study of Tirzepatide in Participants With Impaired Liver Function (NCT03940742) | Eli Lilly and Company | 2019-07-22 |
| IMP4297 Food Effect Trial in Healthy Volunteers (NCT04057729) | Impact Therapeutics, Inc. | 2019-07-22 |
| Topical Acetaminophen for Itch Relief: a Proof of Concept Study in Healthy Subjects (NCT03997851) | University of Miami | 2019-07-22 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Preliminary Activity of Tiragolumab in Participants With Relapsed or Refractory Multiple Myeloma or With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (NCT04045028) | Genentech, Inc. | 2019-07-22 |
| A Study of Lasmiditan (LY573144) in Children Aged 6 to 17 With Migraine (NCT03988088) | Eli Lilly and Company | 2019-07-22 |
| A Safety and Efficacy Study Evaluating CTX110 in Subjects With Relapsed or Refractory B-Cell Malignancies (CARBON) (NCT04035434) | CRISPR Therapeutics AG | 2019-07-22 |
| A Study to Investigate RO7200220 as Monotherapy and in Combination With Ranibizumab in Participants With Diabetic and Uveitic Macular Edema (NCT06771271) | Hoffmann-La Roche | 2019-07-22 |
| A Study of INCMGA00012, INCB001158, and the Combination in Japanese Participants With Advanced Solid Tumors (NCT03910530) | Incyte Biosciences Japan GK | 2019-07-22 |
| Trial of PalloV-CC in Colon Cancer (NCT03827967) | George E. Peoples | 2019-07-20 |
| Comparison of Carbon Dioxide and Saline Flush to Saline Flush in TEVAR and TAVI Procedures to Reduce Cerebral Ischemia (NCT03998631) | University Health Network, Toronto | 2019-07-20 |
| A Study to Assess the Relative Bioavailability of 3 Different Formulations Under Fasted and Fed Condition (NCT04024501) | AstraZeneca | 2019-07-20 |
| Phase 1 Study to Assess the Safety, PK and PD of INBRX-101 in Adults With Alpha-1 Antitrypsin Deficiency (NCT03815396) | Inhibrx Biosciences, Inc | 2019-07-19 |
| Effect of Fluconazole on PK of Fluzoparib in Healthy Male Subjects (NCT04193319) | Jiangsu HengRui Medicine Co., Ltd. | 2019-07-19 |
| A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of PF-06651600 in Subjects With Hepatic Impairment and Healthy Volunteers (NCT04016077) | Pfizer | 2019-07-19 |
| A Pharmacokinetic Study of Omaveloxolone in Subjects With Hepatic Impairment and Normal Hepatic Function (NCT03902002) | Biogen | 2019-07-19 |
| Safety and Tolerability of Escalating Doses of BPN-14967 in Healthy Adults (NCT04005807) | Belite Bio, Inc | 2019-07-19 |
| Safety, Tolerability and Pharmacokinetics of Oral CPL304110, in Adult Subjects With Advanced Solid Malignancies (NCT04149691) | Celon Pharma SA | 2019-07-19 |