| Testing the Safety of Adding Either Monalizumab (IPH2201) or Oleclumab (MEDI9447) to Durvalumab (MEDI4736) Plus Standard Radiation Therapy for Locally Advanced Non-small Cell Lung Cancer (NSCLC), ARCHON-1 Trial (NCT03801902) | National Cancer Institute (NCI) | 2019-10-28 |
| A Study of LY3435151 in Participants With Solid Tumors (NCT04099277) | Eli Lilly and Company | 2019-10-28 |
| Pramipexole and Morphine for Renal Colic (NCT04160520) | East Carolina University | 2019-10-28 |
| A Study of LY3305677 in Participants With Type 2 Diabetes (NCT03928379) | Eli Lilly and Company | 2019-10-27 |
| Myopia Control With Novel Eye Drops (NCT04301323) | Hai Yen Eye Care | 2019-10-26 |
| Pharmacodynamics and Pharmacokinetics of 3 New Developed Coated Glucose Beads in 20 Obese Healthy Subjects (NCT05713773) | Aphaia Pharma US LLC | 2019-10-25 |
| A Study Comparing the Pharmacokinetics and Palatability of Two Candidate Pediatric Powder-for-Oral-Suspension Formulations of Maribavir to the Current Maribavir Tablet Formulation Administered in Healthy Adult Participants (NCT04131556) | Shire | 2019-10-25 |
| Study on the Safety and Efficacy of Cryopreserved Platelets in Hypoproliferative Thrombocytopenic Patients (NCT05067608) | Singapore General Hospital | 2019-10-25 |
| Generation of Biological Samples Positive to Somatropin for Anti-doping Control (NCT04042428) | Parc de Salut Mar | 2019-10-25 |
| Study of eFT226 in Subjects With Selected Advanced Solid Tumor Malignancies (NCT04092673) | Effector Therapeutics | 2019-10-25 |
| Open-label, Dose-escalation Study to Evaluate the Pharmacokinetics of Inhaled Teicoplanin in Cystic Fibrosis Patients (NCT04176328) | Neupharma Srl | 2019-10-25 |
| Efficacy, Safety and Re-occurrence of Pneumothorax and Hydro-pneumothorax With Talc and Pyodine Pleurodesis (NCT04130451) | Dow University of Health Sciences | 2019-10-25 |
| Anakinra for the Treatment of Chronically Inflamed White Matter Lesions in Multiple Sclerosis (NCT04025554) | National Institute of Neurological Disorders and Stroke (NINDS) | 2019-10-25 |
| A Study to Test GlaxoSmithKline's (GSK) Candidate Vaccine-GSK1437173A for Prevention of Shingles in Children With Kidney Transplant (NCT04006808) | GlaxoSmithKline | 2019-10-25 |
| Pharmacokinetics and Safety of PBK-1801 After Single Oral Administration in Healthy Korean Women (NCT04418388) | Pharmbio Korea Co., Ltd. | 2019-10-24 |
| A Study of HR071603(Ketamine Nasal Spray) in Healthy Subjects (NCT04108234) | Jiangsu HengRui Medicine Co., Ltd. | 2019-10-24 |
| Study to Evaluate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic of CC-95775 in Subjects With Advanced Solid Tumors and Relapsed/Refractory Non-Hodgkin Lymphoma (NCT04089527) | Celgene | 2019-10-24 |
| Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial (EnACT) (NCT04031833) | Matinas BioPharma Nanotechnologies, Inc. | 2019-10-24 |
| A Study of MEDI5395 in Combination With Durvalumab in Participants With Select Advanced Solid Tumors (NCT03889275) | MedImmune LLC | 2019-10-24 |
| Rituximab Hyaluronidase in Combination With Chemotherapy in Treating Aggressive B-cell Lymphoma in Uganda (NCT03864419) | Fred Hutchinson Cancer Center | 2019-10-24 |
| Safety and Efficacy of Sonocloud Device Combined With Nivolumab in Brain Metastases From Patients With Melanoma (NCT04021420) | Assistance Publique - Hôpitaux de Paris | 2019-10-24 |
| Study of DCR-A1AT in Healthy Adult Volunteers (NCT04174118) | Dicerna Pharmaceuticals, Inc., a Novo Nordisk company | 2019-10-24 |
| Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels (NCT04008368) | National Heart, Lung, and Blood Institute (NHLBI) | 2019-10-24 |
| Plasmodium Immunotherapy for Advanced Malignant Solid Tumors (NCT04165590) | CAS Lamvac Biotech Co., Ltd. | 2019-10-24 |
| Study of ST266 Given by Intranasal Delivery in Glaucoma Suspect Subjects (NCT03901781) | Noveome Biotherapeutics, formerly Stemnion | 2019-10-23 |
| Optimising Radiation Therapy in Head and Neck Cancers Using Functional Image-Guided Radiotherapy and Novel Biomarkers (NCT04242459) | Royal Marsden NHS Foundation Trust | 2019-10-23 |
| Safety Evaluation of β-arbutin in Healthy Human Subjects (NCT03868748) | SP Nutraceuticals Inc. | 2019-10-23 |
| Dose-Escalation Study to Evaluate the Safety and Tolerability of Intravitreal vMCO-I in Patients With Advanced Retinitis Pigmentosa (NCT04919473) | Nanoscope Therapeutics Inc. | 2019-10-23 |
| A Drug Drug Interaction Study Between PF-06826647 And Oral Contraceptive Steroids In Healthy Female Participants (NCT04134715) | Pfizer | 2019-10-23 |
| A Safety Study of LY3372689 in Healthy Participants (NCT04106206) | Eli Lilly and Company | 2019-10-23 |
| A Study of BCMA-directed CAR-T Cells Treatment in Subjects With r/r Multiple Myeloma (NCT04295018) | Peking Union Medical College Hospital | 2019-10-23 |
| A Study Comparing SIBP-04 and Bevacizumab in Healthy Male Subjects (NCT04135898) | Shanghai Institute Of Biological Products | 2019-10-23 |
| A Study to Test the Cardiac Effects of Padsevonil in Healthy Study Participants (NCT04126343) | UCB Biopharma S.P.R.L. | 2019-10-23 |
| A Study to Test the Interaction of Padsevonil With Oral Contraceptives in Healthy Female Participants (NCT04131517) | UCB Biopharma SRL | 2019-10-23 |
| Patient-Derived Stem Cell Therapy for Diabetic Kidney Disease (NCT03840343) | Mayo Clinic | 2019-10-23 |
| Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome (NCT04047641) | M.D. Anderson Cancer Center | 2019-10-22 |
| Study of Subretinally Injected ATSN-101 Administered in Patients With Leber Congenital Amaurosis Caused by Biallelic Mutations in GUCY2D (NCT03920007) | Atsena Therapeutics Inc. | 2019-10-22 |
| A Clinical Trial of TQB3455 Tablets in Patients With Hematological Malignancies (NCT06550713) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2019-10-22 |
| A Study to Determine the Safety, Tolerability, PK and Preliminary PD of SSS11 in Chinese Healthy Adult Volunteers (NCT04047394) | Shenyang Sunshine Pharmaceutical Co., LTD. | 2019-10-22 |
| Phase I Trial HIPEC With Nal-irinotecan (NCT04088786) | Stony Brook University | 2019-10-22 |
| Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of KPL-404 in Healthy Subjects (NCT04497662) | Kiniksa Pharmaceuticals, Ltd. | 2019-10-22 |
| Intranasal Insulin and Olanzapine Study in Healthy Volunteers (NCT03741478) | Centre for Addiction and Mental Health | 2019-10-22 |
| Binimetinib and Hydroxychloroquine in Treating Patients With KRAS Mutant Metastatic Pancreatic Cancer (NCT04132505) | M.D. Anderson Cancer Center | 2019-10-22 |
| H1N1v Virus Challenge Study in Healthy Subjects (NCT04044352) | National Institute of Allergy and Infectious Diseases (NIAID) | 2019-10-22 |
| MW151-101: First-in-human Study of MW151 (NCT04120233) | Linda Van Eldik | 2019-10-22 |
| Treatment of Central Retinal Vein Occlusion Using Stem Cells Study (NCT03981549) | The Emmes Company, LLC | 2019-10-22 |
| Study Assessing MTD, Safety, Tolerability, PK and Anti-tumor Effects of LNS8801alone and With Pembrolizumab (NCT04130516) | Linnaeus Therapeutics, Inc. | 2019-10-21 |
| A Study of SHP655 (rADAMTS13) in Sickle Cell Disease (NCT03997760) | Shire | 2019-10-21 |
| Nous-209 Genetic Vaccine for the Treatment of Microsatellite Unstable Solid Tumors (NCT04041310) | Nouscom SRL | 2019-10-21 |
| A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Zampilimab in Adult Kidney Transplant Recipients With Chronic Allograft Injury (NCT04335578) | UCB Biopharma SRL | 2019-10-21 |
| A Study to Evaluate the Safety and Tolerability of ONL1204 in Patients With Macula-off, Rhegmatogenous Retinal Detachment (NCT03780972) | ONL Therapeutics | 2019-10-21 |
| Safety and Immunogenicity of a Candidate ZIKV Vaccine (ZIKA001) (NCT04015648) | University of Oxford | 2019-10-21 |
| Relative Bioavailability and PPI Effects of CC-92480 Test and Reference Formulations in Healthy Subjects (NCT04211545) | Celgene | 2019-10-21 |
| Effect of Tegoprazan or RAPA113 on Pharmacodynamics/Pharmacokinetics of Clopidogrel in Healthy Male Volunteers (NCT04171687) | HK inno.N Corporation | 2019-10-21 |
| Transfer of Effector Memory T Cells (Tem) Following Allogeneic Stem Cell Transplantation (NCT03836690) | University College, London | 2019-10-21 |
| Mesenchymal Stem Cell-derived Pleiotropic Factor in Treating Non-healing Wounds (NCT04235868) | Chinese PLA General Hospital | 2019-10-20 |
| A Primary Prevention Intervention for the Promotion of Psycho-social Wellbeing in Adolescent Young Carers: (NCT04114864) | Valentina Hlebec | 2019-10-20 |
| A Study to Assess CYP3A4 Modulator, Oral Contraceptive, and pH Modifier Drug Interactions for ABI-H2158 in Healthy Adults (NCT04142762) | Assembly Biosciences | 2019-10-18 |
| Anti-PD-1 Antibody Combined With Anlotinib in the Treatment of Endometrial Cancer (NCT04157491) | Sun Yat-sen University | 2019-10-18 |
| Examining the Efficacy of Acceptance and Commitment Therapy (ACT) Microinterventions for Distressed First-Generation College Students (NCT04081662) | University of Wisconsin, Madison | 2019-10-18 |
| Glutamine PET Imaging in LAM (NCT04388371) | Vanderbilt University Medical Center | 2019-10-18 |
| Nebulised Liposomal Amphotericin for Invasive Pulmonary Aspergillosis (NAIFI01 Study) (NCT04267497) | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | 2019-10-18 |
| A Phase 1 Study of HS130 in Combination With Viagenpumatucel-L (HS110) in Patients With Solid Tumors (NCT04116710) | Heat Biologics | 2019-10-18 |
| A Pharmacokinetic Study of Zolbetuximab (IMAB362) in Chinese Subjects With Locally Advanced Unresectable or Metastatic Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma (NCT04086758) | Astellas Pharma China, Inc. | 2019-10-18 |
| A Study of Armed, Activated T-Cells in Patients With Advanced Pancreatic Cancer (NCT04137536) | Memorial Sloan Kettering Cancer Center | 2019-10-17 |
| A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of PF-06842874 in Healthy Participants (NCT04124653) | Pfizer | 2019-10-17 |
| Effects of Lithium Therapy on Blood-based Therapeutic Targets in Parkinson's Disease. (NCT04273932) | State University of New York at Buffalo | 2019-10-17 |
| A Clinical Pharmacology Trial of Brexpiprazole Once-weekly (QW) Formulation Administered as Single and Multiple Oral Doses (NCT04118127) | Otsuka Pharmaceutical Co., Ltd. | 2019-10-17 |
| Evaluation of Safety and Tolerability of Libella Gene Therapy for the Treatment of Aging: AAV- hTERT (NCT04133649) | Libella Gene Therapeutics | 2019-10-17 |
| Mesenchymal Stem Cell-derived Pleiotropic Factor in the Treatment of Donor Sites (NCT04234750) | Chinese PLA General Hospital | 2019-10-17 |
| Evaluation of AL3818 in Combination With Nivolumab in Solid Tumors (NCT04165330) | Sarcoma Oncology Research Center, LLC | 2019-10-17 |
| Neuroinflammation After Myocardial Infarction - Imaging Substudy (NCT03968445) | University of Alabama at Birmingham | 2019-10-17 |
| Study of RP2 Monotherapy and RP2 in Combination With Nivolumab in Patients With Solid Tumors (NCT04336241) | Replimune, Inc. | 2019-10-17 |
| Tolerance of Intraperitoneal (IP) Nivolumab After Extensive Debulking Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Ovarian Carcinoma (NCT03959761) | Hospices Civils de Lyon | 2019-10-17 |
| Intravenous (IV) Vitamin C With Chemotherapy for Cisplatin Ineligible Bladder Cancer Patients (NCT04046094) | University of Kansas Medical Center | 2019-10-17 |
| Safety and Tolerability of Cilofexor in Participants With Primary Sclerosing Cholangitis (PSC) and Compensated Cirrhosis (NCT04060147) | Gilead Sciences | 2019-10-17 |
| ERX1000 - Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Male and Female Subjects With Obesity (NCT04890873) | ERX Pharmaceuticals | 2019-10-17 |
| Bioequivalence of 5 Tablets of 100 mg Versus 2 Tablets of 250 mg TF3 of Tepotinib (NCT04204902) | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | 2019-10-17 |
| A Study in Healthy Subjects to Assess the Pharmacokinetics of Savolitinib When Administered Alone and in Combination With Rifampicin (NCT04118842) | AstraZeneca | 2019-10-17 |
| The CHILD Trial: Hypoplastic Left Heart Syndrome Study. (NCT03406884) | Joshua M Hare | 2019-10-16 |
| Positive Affect Promotion to Empower Optimal Adherence to HIV Therapy (NCT04035759) | State University of New York - Downstate Medical Center | 2019-10-16 |
| CLIC-1901 for the Treatment of Patients With Relapsed/Refractory CD19 Positive Hematologic Malignancies (NCT03765177) | Ottawa Hospital Research Institute | 2019-10-16 |
| Staccato Apomorphine Multi-dose PK and PD in Patients With Parkinson's Disease (NCT04157933) | Alexza Pharmaceuticals, Inc. | 2019-10-16 |
| A Study of Lazertinib in Participants With Epidermal Growth Factor Receptor (EGFR) Mutation Positive Advanced Non-Small Cell Lung Cancer (NSCLC) (NCT04075396) | Janssen Research & Development, LLC | 2019-10-16 |
| Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy (NCT04068896) | NGM Biopharmaceuticals, Inc | 2019-10-16 |
| High Dose Steroid Therapy (Prednisone or Methylprednisolone) for the Improvement of Symptoms of Late Radiation-Associated Lower Cranial Neuropathy in Oropharyngeal Cancer Survivors (NCT04151082) | M.D. Anderson Cancer Center | 2019-10-16 |
| A Study of TAK-981 Given With Rituximab in Adults With Relapsed or Refractory CD20-Positive Non-Hodgkin Lymphoma (NCT04074330) | Takeda | 2019-10-15 |
| A Study to Evaluate the Effect of Single-Dose Intravenous Rifampin as a Prototypic Inhibitor of Organic Anion Transporting Polypeptide (OATP) 1B1 and OATP1B3 on the Single-Dose Pharmacokinetics (PK) of Oral TAK-906 in Healthy Adult Participants (NCT04121078) | Millennium Pharmaceuticals, Inc. | 2019-10-15 |
| Evaluation of a Combination of Plant Extracts (BSL_EP028) on Joint Mobility (NCT04029792) | Biosearch S.A. | 2019-10-15 |
| Budesonide With Intratracheal Surfactants in Extremely Preterm Infants (NCT04019106) | University of Manitoba | 2019-10-15 |
| Trial to Assess Safety and Efficacy of MOR202 in Anti-PLA2R + Membranous Nephropathy (aMN) (NCT04145440) | HI-Bio, A Biogen Company | 2019-10-15 |
| TSR-042 in Addition to Standard of Care Definitive Radiation for Inoperable Endometrial Cancer (NCT03955978) | Washington University School of Medicine | 2019-10-15 |
| Effects of Intravenous GSK3858279 on a Battery of Evoked Pain Tests in Healthy Volunteers (NCT04114656) | GlaxoSmithKline | 2019-10-15 |
| AZD6738 & Gemcitabine as Combination Therapy (NCT03669601) | CCTU- Cancer Theme | 2019-10-15 |
| A Trial of CPX-351 Lower Intensity Therapy (LIT) Plus Venetoclax as First Line Treatment for Subjects With AML (NCT04038437) | Jazz Pharmaceuticals | 2019-10-15 |
| A Multiple Ascending Dose Trial of CVL-231 in Subjects With Schizophrenia (NCT04136873) | Cerevel Therapeutics, LLC | 2019-10-15 |
| Japanese Pharmacokinetic Bridging Study for CC-93538 (NCT04096105) | Celgene | 2019-10-14 |
| Phase 1/2 Study of UCART22 in Patients With Relapsed or Refractory CD22+ B-cell Acute Lymphoblastic Leukemia (BALLI-01) (NCT04150497) | Cellectis S.A. | 2019-10-14 |
| Niraparib in Combination with Cabozantinib (XL184) in Patients with Advanced Urothelial Cancer (NICARAGUA) (NCT03425201) | Fundacion CRIS de Investigación para Vencer el Cáncer | 2019-10-14 |
| Dose-Proportionality and Food Effect Study of TNX-102 SL (NCT04164719) | Tonix Pharmaceuticals, Inc. | 2019-10-14 |