| The Effect of Inflammation and Damage to Lymph Node Structures on Durable Protective Immunity Following Yellow Fever Vaccination (NCT04269265) | University of Minnesota | 2020-07-01 |
| A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors (NCT04478279) | Sapience Therapeutics | 2020-07-01 |
| A Study of Fluzoparib Combined With Apatinib as Second-Line Treatment of Patients With Extensive Stage Small Cell Lung Cancer（FA-ES-SCLC） (NCT04659785) | Tianjin Medical University Second Hospital | 2020-07-01 |
| Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs) (NCT04197596) | New York Medical College | 2020-07-01 |
| Study of Exenatide Once-Weekly Suspension in Chinese Patients With Type 2 Diabetes Mellitus (NCT04001231) | AstraZeneca | 2020-06-30 |
| A Study to Test How Well Different Doses of BI 1356225 Are Tolerated by Men and Women With Obesity or Overweight (NCT04447261) | Boehringer Ingelheim | 2020-06-30 |
| A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of UCB8600 in Healthy Participants, Atopic Participants, and Chronic Spontaneous Urticaria Participants (NCT04444466) | UCB Biopharma SRL | 2020-06-30 |
| Monovalent Recombinant COVID19 Vaccine (NCT04453852) | Vaxine Pty Ltd | 2020-06-30 |
| A Study to Assess the Safety, Tolerability and Pharmacokinetics of Multiple Doses of ASP8062 With a Single Dose of Morphine in Recreational Opioid Using Participants (NCT04448561) | Astellas Pharma Global Development, Inc. | 2020-06-30 |
| Testing the Sequential Combination of the Anti-cancer Drugs Olaparib Followed by Adavosertib (AZD1775) in Patients With Advanced Solid Tumors With Selected Mutations and PARP Resistance, STAR Study (NCT04197713) | National Cancer Institute (NCI) | 2020-06-30 |
| Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome (NCT04245397) | Syntrix Biosystems, Inc. | 2020-06-30 |
| A Study to Assess the Mass Balance Recovery, Pharmacokinetics, Metabolite Profile and Metabolite Identification of [14C]AZD4831 (NCT04407091) | AstraZeneca | 2020-06-30 |
| A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression (NCT04274907) | AbbVie | 2020-06-30 |
| Self-control and Body-focused Repetitive Behaviors (NCT04455152) | American University | 2020-06-30 |
| Cyclosporine in Patients With Moderate COVID-19 (NCT04412785) | University of Pennsylvania | 2020-06-30 |
| A Study to Assess the Effect of a Single Dose of ASP8062 on the Multiple Dose Safety, Tolerability and Pharmacokinetics of Buprenorphine/Naloxone in Participants With Opioid Use Disorder (NCT04447287) | Astellas Pharma Global Development, Inc. | 2020-06-29 |
| Pro-Active Genetic Testing in Patients With Solid Tumors, Inherit Study (NCT04456140) | Mayo Clinic | 2020-06-29 |
| Safety of Ascending Doses of Niclosamide (UNI911 INHALATION) in Healthy Volunteers (NCT04576312) | UNION therapeutics | 2020-06-29 |
| Phase 1 Study of SL-172154 (SIRPα-Fc-CD40L) in Subjects With Ovarian Cancer (NCT04406623) | Shattuck Labs, Inc. | 2020-06-29 |
| Study of AMG 910 in Subjects With CLDN18.2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma (NCT04260191) | Amgen | 2020-06-29 |
| An Open-Label Study to Investigate the Safety of Single and Multiple Ascending Doses in Children and Adolescents With Dravet Syndrome (NCT04442295) | Stoke Therapeutics, Inc | 2020-06-29 |
| A Treatment Engagement Protocol for Psychiatrically Hospitalized Adolescents at Clinical High Risk for Psychosis (NCT04314635) | Rhode Island Hospital | 2020-06-29 |
| Study of COVID-19 DNA Vaccine (AG0301-COVID19) (NCT04463472) | AnGes, Inc. | 2020-06-29 |
| Rigosertib Plus Nivolumab for KRAS+ NSCLC Patients Who Progressed on First-Line Treatment (NCT04263090) | Icahn School of Medicine at Mount Sinai | 2020-06-29 |
| A Study to Evaluate the Tolerability and Pharmacokinetics of Jiashen Tablets in Healthy Subjects (NCT04164290) | Tasly Pharmaceutical Group Co., Ltd | 2020-06-29 |
| A Study of Surufatinib Plus Sintilimab in Patients With Advanced Solid Tumor (NCT04427774) | Innovent Biologics (Suzhou) Co. Ltd. | 2020-06-29 |
| Study to Investigate the Receptor Occupancy of HTL0014242 Using [18F] FPEB in Healthy Male Subjects (NCT04462263) | Nxera Pharma UK Limited | 2020-06-29 |
| A Study of BI-1206 in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors (NCT04219254) | BioInvent International AB | 2020-06-29 |
| Efficacy and Safety of JMT101 Combined With Afatinib (or Osimertinib) in Patients With Non-Small Cell Lung Cancer (NCT04448379) | Shanghai JMT-Bio Inc. | 2020-06-29 |
| Tucatinib + Abemaciclib + Herceptin for HER2+ MBC (NCT03846583) | Dana-Farber Cancer Institute | 2020-06-28 |
| A Bioavailability Study of SHR1459 on Healthy Chinese Volunteers (NCT04395053) | Jiangsu HengRui Medicine Co., Ltd. | 2020-06-28 |
| Study of the Safety, Tolerability, Pharmacokinetic Characteristics of PA1010 in Healthy Subjects (NCT05468060) | Zhejiang Palo Alto Pharmaceuticals, Inc. | 2020-06-28 |
| Substudy 02C: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Stage III Melanoma Who Are Candidates for Neoadjuvant Therapy (MK-3475-02C/KEYMAKER-U02) (NCT04303169) | Merck Sharp & Dohme LLC | 2020-06-26 |
| An Open-Label Study of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors (NCT04443088) | Shenzhen Ionova Life Sciences Co., Ltd. | 2020-06-26 |
| Polyethylene Glycol to Improve Sensation Following Digital Nerve Laceration (NCT04270019) | Nova Scotia Health Authority | 2020-06-26 |
| A Study of JNJ-70033093 in Healthy Participants (NCT04448964) | Janssen Research & Development, LLC | 2020-06-26 |
| The Effect of Hepatic Impairment on Aprocitentan Pharmacokinetics (NCT04252495) | Idorsia Pharmaceuticals Ltd. | 2020-06-26 |
| Cariprazine Pediatric ASD PK Study (NCT04382885) | AbbVie | 2020-06-26 |
| A Study to Assess ACH-0145228 When Administered as Immediate Release Tablet Versus Powder-In-Capsule in Healthy Adult Participants (NCT04551586) | Alexion Pharmaceuticals, Inc. | 2020-06-26 |
| CD19-Specific T Cells Post AlloSCT (NCT03579888) | M.D. Anderson Cancer Center | 2020-06-26 |
| Substudy 02A: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents in Participants With Programmed Cell-death 1 (PD-1) Refractory Melanoma (MK-3475-02A/KEYMAKER-U02) (NCT04305041) | Merck Sharp & Dohme LLC | 2020-06-26 |
| Study To Assess The Bioequivalence Under Fed And Fasted Conditions Of The Fesoterodine Beads-In-Capsule SR4 And SR7 Formulations And To Estimate The Bioavailability of SR7 Beads Sprinkled On Apple Sauce Relative To The Beads-In-Capsule SR7 Formulation Administer (NCT04452838) | Pfizer | 2020-06-26 |
| Vemurafenib Plus Copanlisib in Radioiodine-Refractory (RAIR) Thyroid Cancers (NCT04462471) | Memorial Sloan Kettering Cancer Center | 2020-06-26 |
| A Study of Pembrolizumab (MK-3475) in Participants With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL) (MK-3475-A33/KEYNOTE-A33) (NCT04317066) | Merck Sharp & Dohme LLC | 2020-06-26 |
| Study to Investigate the Pharmacokinetic Comparability of Dosing Triferic AVNU IV by Continuous Infusion and IV Bolus. (NCT04409132) | Rockwell Medical Technologies, Inc. | 2020-06-25 |
| A Phase 1 Study of SMP-100 in Normal Healthy Volunteers (NCT04296799) | Chengdu SciMount Pharmatech Co., Ltd. | 2020-06-25 |
| Comparing Dosing Intervals of Nivolumab or Pembrolizumab in Locally Advanced or Metastatic Cancers (NCT04295863) | University of Chicago | 2020-06-25 |
| The Pharmacokinetics, Safety and Tolerability of IN-C009 in Healthy Subjects (NCT05066516) | Korea University Anam Hospital | 2020-06-25 |
| Study to Evaluate the Effect of Repeat-Dose Rifampin on the Pharmacokinetics (PK) of PF-06651600 (NCT04266509) | Pfizer | 2020-06-25 |
| A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Orally Inhaled Aerosolized Hydroxychloroquine Sulfate in Healthy Adult Volunteers (NCT04461353) | Pulmoquine Therapeutics, Inc | 2020-06-25 |
| A Study Evaluating the Drug Levels of Iplimumab Given Under the Skin Alone and in Combination With Nivolumab in Multiple Tumor Types (NCT04311710) | Bristol-Myers Squibb | 2020-06-25 |
| SGLT2 Inhibition in Older Obese Adults With Pre-diabetes (NCT04401904) | The University of Texas Health Science Center at San Antonio | 2020-06-25 |
| Study to Evaluate the Safety and Immunogenicity of KBP-V001 Quadrivalent Influenza Vaccine in Healthy Adults (NCT04439695) | KBio Inc | 2020-06-25 |
| Study of the Safety and Effectiveness of GSK6097608 in Participants With Advanced Solid Tumors (NCT04446351) | GlaxoSmithKline | 2020-06-25 |
| Phase 1/2 Study of APR-246 in Combination With Pembrolizumab in Subjects With Solid Tumor Malignancies (NCT04383938) | Aprea Therapeutics | 2020-06-25 |
| Bioequivalence of Extended Release Nifedipine Tablets in Healthy Chinese Subjects (NCT04438720) | Cao Yu | 2020-06-25 |
| A Study to Evaluate the Tolerance, Efficacy and Pharmacokinetics of TQB3558 Tablets (NCT04408079) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2020-06-25 |
| COVID-19 Vaccine (ChAdOx1 nCoV-19) Trial in South African Adults With and Without HIV-infection (NCT04444674) | University of Oxford | 2020-06-24 |
| A Study to Evaluate the Safety, Tolerability and Efficacy of Intravenous TAK-573 as Part of Combination Therapy in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) (NCT04392648) | Teva Branded Pharmaceutical Products R&D LLC | 2020-06-24 |
| ACE1702 in Subjects With Advanced or Metastatic HER2-expressing Solid Tumors (NCT04319757) | Acepodia Biotech, Inc. | 2020-06-24 |
| Study of Adavosertib(AZD1775) in Japanese Patients With Advanced Solid Tumours (NCT04462952) | AstraZeneca | 2020-06-24 |
| A Phase 1, Single-Ascending-Dose Study of BT051 in Healthy Subjects (NCT05103878) | Bacainn Therapeutics, Inc. | 2020-06-24 |
| A Study to Evaluate Relative Bioavailability, Proton Pump Inhibitor (PPI) (Rabeprazole) Effect, Food Effect and Particle Size Effect of New Acalabrutinib Tablet in Healthy Subjects (NCT04488016) | AstraZeneca | 2020-06-24 |
| Evaluation of Maximum Tolerated Dose, Safety and Efficiency of MSC11FCD Therapy to Recurrent Glioblastoma Patients (NCT04657315) | CHA University | 2020-06-24 |
| Study to Evaluate the Pharmacokinetics and Drug-Drug Interactions of Setanaxib in Healthy Adult Male and Female Subjects (NCT04327089) | Calliditas Therapeutics AB | 2020-06-24 |
| A Study of the Safety, Tolerability, and Bioequivalence of Orally Administered Venglustat in Healthy Adult Participants (NCT06418607) | Sanofi | 2020-06-23 |
| Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer (NCT03203525) | M.D. Anderson Cancer Center | 2020-06-23 |
| Study of Poziotinib in Japanese Patients With NSCLC (NCT04402008) | Spectrum Pharmaceuticals, Inc | 2020-06-23 |
| Tolerability, Efficacy, and PK of ZSP1601 in Patients With Non-Alcoholic Steatohepatitis (NASH) (NCT04140123) | Guangdong Raynovent Biotech Co., Ltd | 2020-06-23 |
| Proof of Concept Study in Patients With Short Bowel Syndrome (NCT04379856) | 9 Meters Biopharma, Inc. | 2020-06-23 |
| Bioequivalence Study of Favipiravir 200 mg Film Tablet (World Medicine, Turkey) Under Fasting Conditions (NCT04407000) | World Medicine ILAC SAN. ve TIC. A.S. | 2020-06-23 |
| Gemcitabine and Cisplatin With or Without CPI-613 as First Line Therapy for Patients With Advanced Unresectable Biliary Tract Cancer (BilT-04) (NCT04203160) | University of Michigan Rogel Cancer Center | 2020-06-23 |
| A Study in Healthy Men to Compare 2 Different Formulations of Alteplase (NCT04419493) | Boehringer Ingelheim | 2020-06-23 |
| Study to Evaluate the Safety, Tolerability, Drug Levels and Drug Effects of BMS-986331 in Healthy Participants (NCT04444050) | Bristol-Myers Squibb | 2020-06-23 |
| Oral EPI-7386 in Patients with Castration-Resistant Prostate Cancer (NCT04421222) | ESSA Pharmaceuticals | 2020-06-23 |
| Effect of Rifampicin on the Pharmacokinetics of SHR6390 in Healthy Subjects (NCT04439578) | Jiangsu HengRui Medicine Co., Ltd. | 2020-06-23 |
| Study to Evaluate the Pharmacokinetic Comparability of CC-93538 From Two Different Drug Concentrations in Healthy Adult Subjects (NCT04373187) | Celgene | 2020-06-22 |
| A Pharmacokinetic Study Comparing the Liraglutide Injection (RD12014) and Victoza® in Healthy Chinese Subjects (NCT05294536) | Sunshine Lake Pharma Co., Ltd. | 2020-06-22 |
| The HALT Biomarker Study (NCT04552275) | Massachusetts General Hospital | 2020-06-22 |
| Study to Assess the Pharmacokinetics and Safety of AZD9977 in Participants With Renal Impairment (NCT04469907) | AstraZeneca | 2020-06-22 |
| Study to Evaluate the Safety and Tolerability of CC-94676 in Participants With Metastatic Castration-Resistant Prostate Cancer (NCT04428788) | Celgene | 2020-06-22 |
| Phase I Clinical Study of Recombinant Novel Coronavirus Vaccine (NCT04445194) | Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. | 2020-06-22 |
| Phase I Study of SYD985 With Niraparib in Patients With Solid Tumors (NCT04235101) | Byondis B.V. | 2020-06-22 |
| Effects of MET-3 and MET-5 on Gut Microbiome and Metabolic Function in Men and Women With Hypertriglyceridemia (NCT04507971) | NuBiyota | 2020-06-22 |
| W-SUDs for COVID-19 (NCT04460027) | Woebot Health | 2020-06-22 |
| A Study of CTX-009 (ABL001) in Combination With Irinotecan or Paclitaxel in Advanced or Metastatic Solid Tumor Patients (NCT04492033) | Handok Inc. | 2020-06-22 |
| Effect of Prebiotics on the Gut Microbiome Profile and Beta Cell Function (NCT04114357) | Indiana University | 2020-06-22 |
| Toradol (Ketorolac) in Breast Surgery to Reduce Pain & Opioid Use (NCT04439396) | Carilion Clinic | 2020-06-22 |
| Pilot Study of an Implantable Microdevice for Evaluating Drug Responses in Situ in Prostate Cancer (NCT04399876) | Brigham and Women's Hospital | 2020-06-22 |
| Autologous Transplantation of Bronchial Basal Cells for Treatment of Bronchiectasis (NCT03655808) | Ruijin Hospital | 2020-06-21 |
| A Mass Balance Study of LCB01-0371 After a Single Oral LCB01-0371 Dose With a [14C]LCB01-0371-microtrace (NCT03492996) | LigaChem Biosciences, Inc. | 2020-06-21 |
| A Therapeutic Trial of Human Amniotic Epithelial Cells Transplantation for Primary Ovarian Failure (NCT02912104) | International Peace Maternity and Child Health Hospital | 2020-06-20 |
| Effects of Tolperisone on Measures of Drowsiness and Cognitive Function (NCT04407377) | Neurana Pharmaceuticals, Inc. | 2020-06-20 |
| NBE-002 in Patients With Advanced Solid Tumors (NCT04441099) | NBE-Therapeutics AG | 2020-06-19 |
| SARS-CoV-2 Antibodies Based IVIG Therapy for COVID-19 Patients (NCT04521309) | Dow University of Health Sciences | 2020-06-19 |
| A Study of LY3832479 (LY-CoV016) in Healthy Participants (NCT04441931) | Eli Lilly and Company | 2020-06-19 |
| Drug-drug Interaction Between DWP14012 and Three Different Kinds of NSAIDs (NCT04490434) | Daewoong Pharmaceutical Co. LTD. | 2020-06-19 |
| A Study in Pregnant Women With Chronic Inflammatory Diseases Treated With Cimzia (Certolizumab Pegol) (NCT04163016) | UCB Biopharma SRL | 2020-06-19 |
| A Study of Different Oral Thin Film (S)-Ketamine Formulations for Sublingual Administration in Healthy Participants (NCT04300621) | Janssen Research & Development, LLC | 2020-06-19 |
| A Study Investigating the Bioavailability of CBD and THC in an Emulsion Product in a Healthy Population (NCT04601207) | New Age Ventures LLC | 2020-06-19 |