| First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumours (NCT04504669) | AstraZeneca | 2020-08-18 |
| A Phase 1, Open-Label, Parallel Group Study to Evaluate the Pharmacokinetics and Safety of DARE-HRT1 in Healthy PostMenopausal Women (NCT05418426) | Daré Bioscience, Inc. | 2020-08-18 |
| A Study of LY3473329 in Healthy Participants (NCT04472676) | Eli Lilly and Company | 2020-08-18 |
| Gemcitabine and Docetaxel With Radiation in Adults With Soft Tissue Sarcoma of the Extremities (NCT04037527) | Wake Forest University Health Sciences | 2020-08-18 |
| Safety and Efficacy Evaluation of AIV001 in Nonmelanoma Skin Cancer of the Low Risk Basal Cell Carcinoma Subtype (NCT04470726) | AiViva BioPharma, Inc. | 2020-08-18 |
| Safety, Tolerability and Pharmacokinetic Characteristics Evaluation of GST-HG131 Tablets (NCT04499443) | Fujian Cosunter Pharmaceutical Co. Ltd | 2020-08-18 |
| A Phase 1 Study to Compare the Safety and Effect of Efgartigimod as an Intravenous Infusion With the Effect of Efgartigimod as a Subcutaneous Injection in Healthy Volunteers (NCT04564066) | argenx | 2020-08-18 |
| Evaluation of Safety, Tolerability, PK/PD, and Metabolism of Single-Dose Singletine(DC407) in Adults (NCT06160401) | Guangzhou JOYO Pharma Co., Ltd | 2020-08-18 |
| 67Cu-SARTATE™ Peptide Receptor Radionuclide Therapy Administered to Pediatric Patients With High-Risk, Relapsed, Refractory Neuroblastoma (NCT04023331) | Clarity Pharmaceuticals Ltd | 2020-08-18 |
| Fractionated and Multiple Dose 225Ac-J591 for Progressive mCRPC (NCT04506567) | Weill Medical College of Cornell University | 2020-08-18 |
| AZD7442 - a Potential Combination Therapy for the Prevention and Treatment of COVID-19 (NCT04507256) | AstraZeneca | 2020-08-18 |
| Study of Danicopan in Participants of Japanese Descent (NCT04451434) | Alexion Pharmaceuticals, Inc. | 2020-08-17 |
| PED NEONAT 20-000599 Fetal Body Composition (NCT04508751) | University of California, Los Angeles | 2020-08-17 |
| The Effect of Inhaled Nitric Oxide on Maximal Oxygen Consumption During Exercise in Hypoxia (NCT04231773) | University of Alberta | 2020-08-17 |
| Antigen-specific T Cell Therapy for Patients With Relapsed Refractory Multiple Myeloma (NCT04505813) | NexImmune Inc. | 2020-08-17 |
| A Study of TAK-981 Given With Pembrolizumab in Participants With Select Advanced or Metastatic Solid Tumors (NCT04381650) | Takeda | 2020-08-17 |
| Study of ARO-HIF2 in Patients With Advanced Clear Cell Renal Cell Carcinoma (NCT04169711) | Arrowhead Pharmaceuticals | 2020-08-17 |
| A Study of ALG-010133 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB Subjects (NCT04485663) | Aligos Therapeutics | 2020-08-17 |
| Recombinant, Bivalent, Norovirus Vaccine Study (NCT05508178) | Icon Genetics GmbH | 2020-08-17 |
| A Study of JNJ-53718678 in Participants With Hepatic Impairment (NCT04332523) | Janssen Research & Development, LLC | 2020-08-17 |
| Electrical Brain Stimulation and Pharmacological Treatments in Autism Spectrum Disorder (NCT05491720) | The National Brain Mapping Laboratory (NBML) | 2020-08-15 |
| Yeast Cells as Antioxidant-Producing Probiotics (NCT02814695) | Benha University | 2020-08-15 |
| Safety and Preliminary Efficacy of ATG-017 Monotherapy or Combination Therapy With Nivolumab in Advanced Solid Tumors and Hematological Malignancies (NCT04305249) | Antengene Therapeutics Limited | 2020-08-15 |
| PVP-I Nasal Sprays and SARS-CoV-2 Nasopharyngeal Titers (for COVID-19) (NCT04347954) | Stanford University | 2020-08-15 |
| A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics of DW1809 (NCT05214677) | Daewon Pharmaceutical Co., Ltd. | 2020-08-15 |
| PK Study on Ready-to-Use Injection (VSLI-RTU) 1 Vial & 3 Vial Formulation Marqibo® in Hematological Malignant Patients (NCT04243434) | Acrotech Biopharma Inc. | 2020-08-15 |
| Safety, Tolerability, and Pharmacokinetics of Single Dose TenoMiR as a Treatment for Tennis Elbow (NCT04670289) | Causeway Therapeutics | 2020-08-14 |
| Radiation Therapy in Combination With Durvalumab for People With Pancreatic Cancer (NCT03245541) | Memorial Sloan Kettering Cancer Center | 2020-08-14 |
| Haplo Peripheral Blood Sct In GVHD Prevention (NCT04473911) | Zachariah Michael DeFilipp | 2020-08-14 |
| Study of Multiple Ascending Dose of KBL693 in Healthy Participants (NCT04307173) | KoBioLabs | 2020-08-14 |
| PET/CT Quantitative Assessment of Myocardial Blood Flow Changes in Oncologic Patients Receiving Checkpoint Inhibitor Therapy (NCT04538950) | Mayo Clinic | 2020-08-14 |
| CLBR001 and SWI019 in Patients With Relapsed / Refractory B-cell Malignancies (NCT04450069) | Calibr, a division of Scripps Research | 2020-08-14 |
| Sintilimab Plus Hypofractionated Radiotherapy for MSI-H/dMMR Rectal Cancer (NCT04636008) | West China Hospital | 2020-08-14 |
| Posiphen® Dose-Finding, Biomarker Study in Early Alzheimer's and Parkinson's Patients (NCT04524351) | Annovis Bio Inc. | 2020-08-14 |
| Drug-drug Interaction Study of Gepotidacin (NCT04493931) | GlaxoSmithKline | 2020-08-14 |
| A Study to Assess the Effect of a High Fat Meal on Surufatinib in Healthy Subjects (NCT04372394) | Hutchison Medipharma Limited | 2020-08-14 |
| A Study to Evaluate Pirtobrutinib (LOXO-305) in Healthy Adult Participants (NCT06181006) | Eli Lilly and Company | 2020-08-14 |
| IA Injection of Rejoint Gel and PRP in Patients With Unilateral Knee OA (NCT04519047) | National Taiwan University Hospital | 2020-08-13 |
| A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single Ascending Dose and Multiple Doses With Titration of TAK-935 in Healthy Japanese Participants (NCT04461483) | Takeda | 2020-08-13 |
| A Study in Healthy Men to Test How Different Doses of BI 1595043 Are Tolerated (NCT04439838) | Boehringer Ingelheim | 2020-08-13 |
| Bioequivalence Study of Favipiravir From Flupirava 200 mg Tablet (European Egyptian Pharmaceutical Industries , Egypt) Versus Avigan 200 mg Tablets (Man. by Toyama Chemical Co., Ltd Japan) (NCT04478448) | Genuine Research Center, Egypt | 2020-08-13 |
| A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics of DW1809-T2 (NCT05214690) | Daewon Pharmaceutical Co., Ltd. | 2020-08-13 |
| A First in Human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Inhaled ETD002 in Healthy Subjects (NCT04488705) | Enterprise Therapeutics Ltd | 2020-08-13 |
| A Study to Evaluate Pharmacokinetics/Pharmacodynamics and Safety/Tolerability of IN-C005 in Healthy Male Subjects (NCT04485884) | HK inno.N Corporation | 2020-08-13 |
| WD-1603 PK Study Under Fasting and Fed Conditions in Healthy Subjects (NCT04513340) | Hong Kong WD Pharmaceutical Co., Limited | 2020-08-13 |
| A Dose Escalation/Expansion Study of Oral OP-1250 in Subjects With Advanced and/or Metastatic HR+, HER2- Breast Cancer (NCT04505826) | Olema Pharmaceuticals, Inc. | 2020-08-13 |
| A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TST001 in Advanced or Metastatic Solid Tumors (NCT04495296) | Suzhou Transcenta Therapeutics Co., Ltd. | 2020-08-13 |
| Pharmacokinetics, Safety, Tolerability, and Immunogenicity of Two Formulations of SB5 in Healthy Male Subjects (NCT04514796) | Samsung Bioepis Co., Ltd. | 2020-08-13 |
| A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab + Lenalidomide (+Len), and the Safety, Tolerability, and Pharmacokinetics of SC Versus IV Mosunetuzumab + Len in Participants With Follicular Lymphoma (NCT04246086) | Hoffmann-La Roche | 2020-08-12 |
| A Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetic Profile of a Single Doses of MMV533. (NCT04323306) | Medicines for Malaria Venture | 2020-08-12 |
| Investigate Safety, Tolerability, PK/PK of J2H 1702 in Healthy Males (NCT06308861) | J2H Biotech | 2020-08-12 |
| A Study With Jaktinib Hydrochloride Cream Applied Topically to Subjects With Alopecia Areata (NCT04445363) | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 2020-08-12 |
| Viral Specific T-Lymphocytes to Treat Adenovirus, CMV and EBV (NCT04364178) | Jessie L. Alexander, MD | 2020-08-12 |
| Ascending Dose Study of HU6 in Healthy Volunteers (NCT04463017) | Rivus Pharmaceuticals, Inc. | 2020-08-12 |
| Study on the Safety of BAY1817080 How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug Given to Participants With Moderate Renal Impairment and End Stage Renal Disease Requiring Dialysis Compared With Matched Participants With Normal Renal Function (NCT04471337) | Bayer | 2020-08-12 |
| Study to Assess the Safety, Tolerability, Effects on the Body, Absorption, Distribution and Elimination of 25 mg BAY2433334 in Renal Impairment Including Renal Replacement Therapy ("Dialysis") (NCT04510987) | Bayer | 2020-08-12 |
| Short-term Fasting Prior to PD-1/PD-L1 Inhibitor Therapy for of Advanced or Metastatic Skin Malignancy (NCT04387084) | University of Southern California | 2020-08-12 |
| An Investigational Scan (hpMRI) for Monitoring Treatment Response in Patients With Thyroid Cancer and Other Malignancies of the Head and Neck Undergoing Radiation Therapy and/or Systemic Therapy (NCT04589624) | M.D. Anderson Cancer Center | 2020-08-12 |
| A Study to Evaluate the Pharmacokinetics of Single Oral Doses of Ozanimod in Healthy Adult Chinese Subjects (NCT04211558) | Celgene | 2020-08-12 |
| TT52CAR19 Therapy for B-cell Acute Lymphoblastic Leukaemia (B-ALL) (NCT04557436) | Great Ormond Street Hospital for Children NHS Foundation Trust | 2020-08-12 |
| Apixaban vs Enoxaparin Following Microsurgical Breast Reconstruction-An RCT (NCT04504318) | Stanford University | 2020-08-12 |
| A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies (NCT04503265) | AtlasMedx, Incorporated | 2020-08-12 |
| First-in-Human (FIH) Clinical Study of NM8074 in Healthy Adult Volunteers (NCT05642546) | NovelMed Therapeutics | 2020-08-12 |
| Study of IMC-I109V in Non-cirrhotic HBeAg-negative Chronic HBV Infection (NCT05867056) | Immunocore Ltd | 2020-08-12 |
| Sintilimab in the Treatment of Advanced and Refractory Pediatric Malignant Tumors (NCT04400851) | Sun Yat-sen University | 2020-08-11 |
| Safety and Tolerability of GX-P1 in Healthy Male Volunteers (NCT04298749) | Genexine, Inc. | 2020-08-11 |
| Short-Course Chemoradiotherapy Followed by Chemotherapy for the Treatment of Resectable Gastric Adenocarcinoma (NCT04523818) | M.D. Anderson Cancer Center | 2020-08-11 |
| PAveMenT: Palbociclib and Avelumab in Metastatic AR+ Triple Negative Breast Cancer (NCT04360941) | Royal Marsden NHS Foundation Trust | 2020-08-11 |
| Study of Sitravatinib, Nivolumab and Ipilimumab in Advanced or Metastatic Clear-Cell Renal Cell Carcinoma or Other Solid Malignancies (NCT04518046) | Mirati Therapeutics Inc. | 2020-08-11 |
| The Multiple Dose of PK/PD Study of SHR2285 Tablets in Healthy Subjects (NCT04229433) | Jiangsu HengRui Medicine Co., Ltd. | 2020-08-11 |
| Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating Gliomas (NCT04772456) | University of Maryland, Baltimore | 2020-08-11 |
| PLX2853 as a Single Agent in Advanced Gynecological Malignancies and in Combination With Carboplatin in Platinum-Resistant Epithelial Ovarian Cancer (NCT04493619) | Opna Bio LLC | 2020-08-11 |
| A Study of Ad26.COV2.S in Adults (COVID-19) (NCT04509947) | Janssen Pharmaceutical K.K. | 2020-08-11 |
| HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers (NCT04432597) | National Cancer Institute (NCI) | 2020-08-11 |
| A Study of the Biodistribution and Safety of [18F]GTP1 in Healthy Japanese Participants (NCT04394845) | Genentech, Inc. | 2020-08-11 |
| Camrelizumab in Combination With Neoadjuvant Chemotherapy for Resectable Thoracic Esophageal Squamous Cell Carcinoma (NCT04506138) | Zhejiang Cancer Hospital | 2020-08-11 |
| A Study of HNC664 in Healthy Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics (NCT04504448) | Guangzhou Henovcom Bioscience Co. Ltd. | 2020-08-11 |
| Alleviate-HF-1 Study (NCT04583527) | Alleviant Medical, Inc. | 2020-08-11 |
| Intra-arterial Chemotherapy for Retinoblastoma (NCT04342572) | Washington University School of Medicine | 2020-08-11 |
| A Multiple Ascending Dose Study to Investigate Safety of KBP-7072 in Healthy Subjects (NCT04532957) | KBP Biosciences | 2020-08-11 |
| Careseng 1370 for Healthy Volunteers (NCT03974516) | i Cure Biotech Co., Ltd. | 2020-08-10 |
| The Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of HEC96719 Tablets in Healthy Subjects (NCT04422496) | Sunshine Lake Pharma Co., Ltd. | 2020-08-10 |
| Phase I Study to Assess the Safety and Immunology of a COVID-19 Vaccine With GRAd-COV2 Vaccine (NCT04528641) | ReiThera Srl | 2020-08-10 |
| Bioequivalence Study of Fingolimod From Sphingomod 0.5 mg Hard Gelatin Capsules (Hikma Pharma, Egypt) Versus Gilenya 0.5 mg Hard Capsules (Novartis Pharma AG, Basle, Switzerland). (NCT04657744) | Genuine Research Center, Egypt | 2020-08-10 |
| Study of the Tolerability and Pharmacokinetics of Oral Doses of SAR442168 With a Food Effect Investigation in Healthy Adult Participants (NCT06106074) | Sanofi | 2020-08-10 |
| A Study to Determine the Safety, Tolerability, and Pharmacokinetics of Lanadelumab Administered Intravenously in Healthy Adult Volunteer Participants (NCT04503603) | Takeda | 2020-08-10 |
| Study of Purinostat Mesylate for Injection in the Treatment of Relapsed or Refractory B Cell-related Tumor-predominant (NCT05526313) | Chengdu Zenitar Biomedical Technology Co., Ltd | 2020-08-10 |
| Clinical Trial to Evaluate the Safety and Immunogenicity of the COVID-19 Vaccine (NCT04497298) | Institut Pasteur | 2020-08-10 |
| Phase I Study of Marizomib + Panobinostat for Children With DIPG (NCT04341311) | Dana-Farber Cancer Institute | 2020-08-10 |
| TAEK-VAC-HerBy Vaccine for Brachyury and HER2 Expressing Cancer (NCT04246671) | Bavarian Nordic | 2020-08-10 |
| Pharmacokinetic Study of Aztreonam-Avibactam in Severe Renal Impairment (NCT04486625) | Pfizer | 2020-08-10 |
| A Study to Investigate the Effect of Renal Impairment on the Safety and Tolerability of Fezolinetant Compared to Participants With Normal Renal Function (NCT04476849) | Astellas Pharma Global Development, Inc. | 2020-08-10 |
| Study of FURMONERTINIB in Patients With NSCLC Having Exon 20 Insertion Mutation (NCT04858958) | Allist Pharmaceuticals, Inc. | 2020-08-10 |
| Comparative Study to Evaluate the Pharmacokinetics of BAT2206 vs Stelara® in Healthy Subjects (NCT04371185) | Bio-Thera Solutions | 2020-08-08 |
| Study of Edasalonexent With Midazolam and Deflazacort in Healthy Subjects (NCT04543370) | Catabasis Pharmaceuticals | 2020-08-08 |
| A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Single Oral Dose of Maribavir Administered in Healthy Japanese Participants Compared With Matched, Healthy, Non-Hispanic, Caucasian Participants and to Assess Dose-Proportionality of 3 Doses of Maribavir in Japanese Participants (NCT04497883) | Shire | 2020-08-07 |
| Losartan to Improve Hip Microfracture (NCT04212650) | Steadman Philippon Research Institute | 2020-08-07 |
| A Clinical Study to Evaluate MW33 Injection (NCT04533048) | Mabwell (Shanghai) Bioscience Co., Ltd. | 2020-08-07 |
| AT-301 Nasal Spray in Healthy Adults (NCT04519788) | Atossa Therapeutics, Inc. | 2020-08-07 |
| Nelfinavir, Cisplatin, and External Beam Radiation Therapy for the Treatment of Locally Advanced Vulvar Cancer That Cannot Be Removed by Surgery (NCT04169763) | M.D. Anderson Cancer Center | 2020-08-07 |