| Evaluation of Mass Balance and Absolute Bioavailability of GLPG1205 (NCT04704739) | Lakefront Biotherapeutics NV | 2021-01-13 |
| Study of ALXN1820 in Healthy Adult Participants (NCT04631562) | Alexion Pharmaceuticals, Inc. | 2021-01-13 |
| A Study of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Advanced Solid Tumor (NCT04719065) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2021-01-13 |
| An Open-label, Uncontrolled Study of ONO-4578 and ONO-4538 in Combination With Standard-of-care Modified FOLFIRINOX (mFFX) or Gemcitabine Plus Nab-paclitaxel (GnP) Therapy as First-line Treatment in Patients With Metastatic Pancreatic Cancer (NCT06538207) | Ono Pharmaceutical Co., Ltd. | 2021-01-13 |
| Assessment of Safety and Therapeutic Efficacy of Promitil in Combination With Folfox in Patients With GI Malignancies (NCT04729205) | Lipomedix Pharmaceuticals Inc. | 2021-01-13 |
| SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells (NCT04150042) | General Oncology, Inc. | 2021-01-13 |
| A Phase 1 SAD/MAD Study of RLS-0071 in Healthy Volunteers in Support of a COVID-19 Development Program (NCT05298787) | ReAlta Life Sciences, Inc. | 2021-01-13 |
| A Pilot Randomized Controlled Trial for Feasibility of Administering an AR Game to Postoperative Pediatric Cancer Patients (NCT04674150) | ALTality, Inc. | 2021-01-13 |
| Pharmacokinetics and Safety of ALA in Acne Vulgaris (NCT04044898) | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. | 2021-01-12 |
| Novel Clinical Target in Fragile X Syndrome (NCT04314856) | Guido A. Davidzon, MD, SM | 2021-01-12 |
| Study to Evaluate the Pharmacokinetics of CIN-107 in Subjects With Varying Degrees of Renal Function (NCT05470725) | AstraZeneca | 2021-01-12 |
| A Study to Evaluate the Effect of a Dual CYP2C19 and CYP3A4 Inhibitor, Fluconazole, on the Pharmacokinetics of Fedratinib in Healthy Adult Subjects (NCT04702464) | Celgene | 2021-01-12 |
| IS-free Treg HaploHCT (NCT04678401) | Dana-Farber Cancer Institute | 2021-01-12 |
| Study of JTX-8064, as Monotherapy and in Combination With a PD-1 Inhibitor, in Adult Subjects With Advanced Refractory Solid Tumors (NCT04669899) | Jounce Therapeutics, Inc. | 2021-01-12 |
| Effect of Probiotics in Non-alcoholic Fatty Liver Disease and Steatohepatitis (NCT04175392) | Corewell Health East | 2021-01-12 |
| Safety and Tolerability Evaluation of Low-dose Radiation in Combination With CS1001 in Relapsed SCLC Patients (NCT04421352) | CStone Pharmaceuticals | 2021-01-12 |
| A Study of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Relapsed Ovarian Cancer (NCT04718376) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2021-01-12 |
| Activity of NCO-48 Fumarate in Treatment-Naive Adults With Chronic Hepatitis B (NCT04629976) | Nucorion Pharmaceuticals, Inc. | 2021-01-12 |
| Study of Safety, Efficacy, and Pharmacokinetics of Topical ACD440 in Healthy Volunteers (NCT04704232) | AlzeCure Pharma | 2021-01-12 |
| Study of Adoptive Immunotherapy in Relapsed and Non-resectable Sarcomas After Multimodal Treatment. (NCT04802070) | Prof. Franca Fagioli | 2021-01-11 |
| A Study to Assess Relative Bioavailability of and Effect of Food on a New Oral Tablet Formulation of GLPG3970 (NCT04708184) | Lakefront Biotherapeutics NV | 2021-01-11 |
| Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer (NCT04172532) | National Cancer Institute (NCI) | 2021-01-11 |
| A Study to Evaluate the Efficacy and Safety of QL1706 Injection in Patients With Solid Tumors (NCT05171790) | Qilu Pharmaceutical Co., Ltd. | 2021-01-11 |
| Drug-drug Interaction Study with GLPG3970 and Sulfasalazine in Adult, Healthy Subjects (NCT04720183) | Lakefront Biotherapeutics NV | 2021-01-11 |
| Dose Escalation Study of Immunomodulatory Nanoparticles (NCT04751786) | Radboud University Medical Center | 2021-01-11 |
| Study of PAC-1 and Entrectinib for Patients With Metastatic Uveal Melanoma (NCT04589832) | Arkadiusz Z. Dudek, MD | 2021-01-11 |
| RU Anti-SARS-CoV-2 (COVID-19) mAbs in Healthy Volunteers (NCT04700163) | Rockefeller University | 2021-01-11 |
| A Study Comparing the Pharmacokinetic Similarity of MB02-SP, MB02-DM and US Licensed-Avastin®. (NCT04408989) | mAbxience Research S.L. | 2021-01-11 |
| A Study of Effect of Multiple Doses of LOXO-305 on the Pharmacokinetics of Single Oral Doses of CYP1A2, CYP2C9, CYP2C19 Substrates in Healthy Participants (NCT06215430) | Eli Lilly and Company | 2021-01-11 |
| TNFα and IL-2 Coding Oncolytic Adenovirus TILT-123 Monotherapy (NCT04695327) | TILT Biotherapeutics Ltd. | 2021-01-11 |
| Drug-drug Interaction Study of Evobrutinib With Midazolam in Healthy Participants (NCT04697511) | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | 2021-01-11 |
| Phase 1 Evaluation of (2R,6R)-Hydroxynorketamine (NCT04711005) | National Institute of Mental Health (NIMH) | 2021-01-11 |
| A Study to Test Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Intravenous Doses of Zampilimab in Healthy Participants (NCT04705350) | UCB Biopharma SRL | 2021-01-11 |
| Study of IGC-AD1 in Subjects With Dementia Due to Alzheimer's Disease (NCT04749563) | IGC Pharma, LLC | 2021-01-11 |
| Cannabidiol Treatment for Severe and Critical Coronavirus (COVID-19) Pulmonary Infection (NCT04731116) | Rabin Medical Center | 2021-01-10 |
| GLS4/RTV and TAF Drug-drug Interaction (NCT04551261) | Sunshine Lake Pharma Co., Ltd. | 2021-01-10 |
| A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-348 (NCT04660370) | Chong Kun Dang Pharmaceutical | 2021-01-09 |
| A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement (NCT04543188) | Pfizer | 2021-01-08 |
| Donafenib and Toripalimab Combined With TACE in Patients With Unresectable Hepatocellular Carcinoma (NCT04605185) | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 2021-01-08 |
| A Randomized Study Investigating Oral Desmetramadol Dose Proportionality and Food Effect In Normal Human Subjects (NCT04683926) | Syntrix Biosystems, Inc. | 2021-01-08 |
| A Study to Evaluate Glofitamab as Single Agent Administered After Pretreatment With Obinutuzumab in Chinese Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (NCT04657302) | Hoffmann-La Roche | 2021-01-08 |
| Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies (NCT04282044) | BioEclipse Therapeutics | 2021-01-08 |
| Study to AntagOnize Plasminogen Activator Inhibitor-1 in Severe COVID-19 (NCT04634799) | Northwestern University | 2021-01-08 |
| Drug-durg Interaction of SHR3680 With Digoxin, Rosuvastatin Calcium and Metformin Hydrochloride (NCT04621669) | Jiangsu HengRui Medicine Co., Ltd. | 2021-01-08 |
| Phase 1 to Evaluate the Safety and Pharmacokinetic Characteristics of Fixed-dose Combination of YYC506 (NCT04874129) | Yooyoung Pharmaceutical Co., Ltd. | 2021-01-07 |
| Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-9545 Following a Single Oral Dose (Part 1) and to Evaluate the Absolute and Relative Bioavailability of Oral Capsule Formulations of GDC-9545 (Part 2) in Healthy Female Subjects of Non-Childbearing Potential (NCT04680273) | Genentech, Inc. | 2021-01-07 |
| Study to Assess the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of GEn1E-1124 (NCT04728061) | GEn1E Lifesciences | 2021-01-07 |
| This is a Phase 1 Study of MH048 in Patients With Selected Relapsed/Refractory B-cell Malignancies (NCT04689308) | Minghui Pharmaceutical (Shanghai) LTD | 2021-01-07 |
| A Study of TAK-919 in Healthy Japanese Adults (COVID-19) (NCT04677660) | Takeda | 2021-01-07 |
| Leflunomide for the Treatment of Severe COVID-19 in Patients With a Concurrent Malignancy (NCT04532372) | City of Hope Medical Center | 2021-01-07 |
| A Study in Healthy Men to Test How Different Doses of BI 474121 Are Taken up and How They Influence the Amount of a Molecular Messenger (cGMP) in the Spinal Fluid (NCT04672954) | Boehringer Ingelheim | 2021-01-07 |
| Safety and Tolerability Study for T-1101 (Tosylate) Capsules to Treat Advanced Refractory Solid Tumors (NCT04685473) | Taivex Therapeutics Corporation | 2021-01-07 |
| Phenotyping of High Dose Rifampicin (NCT04525235) | Radboud University Medical Center | 2021-01-07 |
| NTX-301 in MDS/AML (NCT04167917) | University of Alabama at Birmingham | 2021-01-06 |
| CMV-TCR-T Cells for Refractory CMV Infection After HSCT (NCT05089838) | Xiao-Jun Huang | 2021-01-06 |
| A Single Dose Bioequivalence Study of WD-1602 Versus Pradaxa® in Healthy Subjects Under Fed Condition (NCT04592822) | Hong Kong WD Pharmaceutical Co., Limited | 2021-01-06 |
| Safety of SNK01 in Subjects With Alzheimer's Disease (ASK-AD) (NCT04678453) | NKGen Biotech, Inc. | 2021-01-06 |
| A Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Participants With Moderate to Severe Obstructive Sleep Apnea, and in Adult and Elderly Participants With Moderate to Severe Chronic Obstructive Pulmonary Disease (NCT04647383) | Eisai Inc. | 2021-01-06 |
| Relative Bioavailability Study of SHR3680 (NCT04903158) | Jiangsu HengRui Medicine Co., Ltd. | 2021-01-06 |
| Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults (NCT04723602) | Albert B. Sabin Vaccine Institute | 2021-01-06 |
| A Study to Compare the Pharmacokinetics and Safety of Mitapivat 100 mg Tablet Formulation With Mitapivat 2 × 50 mg Tablet Formulation in Healthy Adult Participants (NCT04696393) | Agios Pharmaceuticals, Inc. | 2021-01-06 |
| A Study of the Effects of Erythromycin on the Pharmacokinetics of Relugolix, Estradiol, and Norethindrone in Healthy Postmenopausal Women and on the Pharmacokinetics of Relugolix in Healthy Adult Men (NCT04714554) | Myovant Sciences GmbH | 2021-01-06 |
| Polaprezinc Treatment for Enzalutamide- or Abiraterone-resistant CRPC (NCT05549778) | Jiangnan University | 2021-01-06 |
| Patient-centered Modular CBT for CPTSD: A Randomised Controlled Pilot Study (NCT05259592) | Danish Veterans Centre | 2021-01-05 |
| Conservative Treatment of Catheter - Related Injections With Gentamicine/EDTA (NCT04789928) | Institut Pasteur | 2021-01-05 |
| A Study of ION537 in Patients With Molecularly Selected Advanced Solid Tumors (NCT04659096) | Ionis Pharmaceuticals, Inc. | 2021-01-05 |
| A Study in Healthy Participants to Assess the Effect of Darunavir, Emtricitabine, and Tenofovir Alafenamide in the Presence of Cobicistat as Fixed Dose Combination (Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide) Compared With Co-administration of the Separate Agents (NCT04661397) | Janssen Research & Development, LLC | 2021-01-05 |
| Plazomicin Study in ESRD Patients Receiving IHD (NCT04699656) | Cipla USA Inc. | 2021-01-05 |
| A Phase 1 Study of Human Monoclonal Antibodies, BRII-196 and BRII-198 (NCT04691180) | Brii Biosciences Limited | 2021-01-05 |
| Bioequivalence Study of Tacrolimus in Healthy Volunteers (NCT04725682) | Food and Drug Administration (FDA) | 2021-01-05 |
| SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin in Combination With Irinotecan in Ewing Sarcoma Patients (NCT04067115) | Sarcoma Alliance for Research through Collaboration | 2021-01-05 |
| Wellbeing After Stroke (WAterS): Supporting Adjustment and Wellbeing After Stroke (NCT04655937) | University of Manchester | 2021-01-05 |
| Low-dose Interleukin-2 in Women With Unexplained Miscarriages (NCT03970954) | Assistance Publique - Hôpitaux de Paris | 2021-01-05 |
| Efficacy of Different Toothbrushes and Hygiene Regimen (NCT04216069) | University of Nove de Julho | 2021-01-05 |
| Receptor Occupancy of LB-102 Using Positron Emission Tomography (PET) in Healthy Volunteers (NCT04588129) | LB Pharmaceuticals Inc. | 2021-01-05 |
| Effect of Local Application of Simvastatin Versus Bone Powder on Implant Bone Changes (NCT06016218) | British University In Egypt | 2021-01-05 |
| Olaparib and Durvalumab With Carboplatin, Etoposide, and/or Radiation Therapy for the Treatment of Extensive-Stage Small Cell Lung Cancer, PRIO Trial (NCT04728230) | M.D. Anderson Cancer Center | 2021-01-05 |
| A Safety and Tolerability Study of Neural Stem Cells (NR1) in Subjects With Chronic Ischemic Subcortical Stroke (ISS) (NCT04631406) | Clarion Cells, Inc. | 2021-01-04 |
| Study to Evaluate Oral Mucosa Absorption of IN-C004 in Healthy Volunteers (NCT04654065) | HK inno.N Corporation | 2021-01-04 |
| Targeting CD19 and CD22 CAR-T Cells Immunotherapy in Patients With Relapsed or Refractory B Cell Lymphoma (NCT04715217) | Shanxi Province Cancer Hospital | 2021-01-04 |
| A Clinical Study of MIL95 in Advanced Malignancies. (NCT04651348) | Beijing Mabworks Biotech Co., Ltd. | 2021-01-04 |
| Study on TIL for the Treatment of r/r Gynecologic Tumors (NCT04766320) | Shanghai 10th People's Hospital | 2021-01-04 |
| A Study to Evaluate the Safety and Tolerability of RO7296682 in Combination With Atezolizumab in Participants With Advanced Solid Tumors. (NCT04642365) | Hoffmann-La Roche | 2021-01-04 |
| A Phase 1b Study of PUR1800 in Patients With COPD (NCT04759807) | Pulmatrix Inc. | 2021-01-04 |
| A Study of Subcutaneous Blinatumomab Administration in Participants With R/R and MRD+ B-ALL (NCT04521231) | Amgen | 2021-01-04 |
| A Study of the Effect of Food on Pirtobrutinib (LOXO-305) in Healthy Participants (NCT06180980) | Eli Lilly and Company | 2021-01-04 |
| The Effectiveness of Phytotherapy in SARS-COV2(COVID-19) (NCT04851821) | Hôpital Universitaire Sahloul | 2021-01-04 |
| Multiple Ascending Dose Study of HU6 in High BMI Volunteers (NCT04709913) | Rivus Pharmaceuticals, Inc. | 2021-01-04 |
| Pharmacokinetics (PK) of Rilzabrutinib (PRN1008) in Healthy Japanese and Caucasian Subjects (NCT06444191) | Principia Biopharma, a Sanofi Company | 2021-01-04 |
| Bioequivalence Clinical Trial of Recombinant Human Follicle-stimulating Hormone JZB30 (NCT06778304) | West China Second University Hospital | 2021-01-04 |
| Levofloxacin Ocular Implant for Ocular Surgery (NCT04682288) | PolyActiva Pty Ltd | 2021-01-04 |
| A Study of XW001 in Healthy Adult Subjects (NCT05642403) | Hangzhou Sciwind Biosciences Co., Ltd. | 2021-01-03 |
| A Phase I Study to Evaluate Safety and Pharmacokinetics of Escalating Single Doses and Multiple Doses of SP-8356 (NCT05574166) | Shin Poong Pharmaceutical Co. Ltd. | 2021-01-03 |
| Fase I Clinical Trial on NK Cells for COVID-19 (NCT04634370) | Hospital de Clinicas de Porto Alegre | 2021-01-02 |
| Ketofol Versus Fenofol as Procedural Sedation for Carpal Tunnel Release (NCT04686448) | Zagazig University | 2021-01-01 |
| Topical Cream SNG100 for Treatment in Moderate Atopic Dermatitis Subjects. (NCT04615962) | Seanergy Dermatology Ltd. | 2021-01-01 |
| Preventing de Novo Portal Vein Thrombosis With Antithrombin-III in Patients With Cirrhosis (NCT04055389) | Jonathan Stine | 2021-01-01 |
| Comparison Between Topical Mitomycin C and Cyclosporine (NCT05627947) | Egymedicalpedia | 2021-01-01 |
| Effect of Subcutaneous Polyvidone Collagen Treatment on Hand Recovery in Adult Rheumatoid Arthritis. (NCT06656169) | Instituto Mexicano del Seguro Social | 2021-01-01 |
| 5FU/LV, Irinotecan, Temozolomide and Bevacizumab for MGMT Silenced, Microsatellite Stable Metastatic Colorectal Cancer. (NCT04689347) | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 2021-01-01 |