| Sapanisertib and Nivolumab for the Treatment of Stage I-IV Non-small Cell Lung Cancer in Patients Who Have Progressed on Prior PD-1/PD-L1 Inhibitor Therapy, I-OVERCOME Study (NCT05022394) | M.D. Anderson Cancer Center | 2021-02-18 |
| Fecal Microbiota Transplantation to Improve Efficacy of Immune Checkpoint Inhibitors in Renal Cell Carcinoma (NCT04758507) | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 2021-02-18 |
| Clinical Trial to Investigate the Pharmacokinetics and Safety of CKD-393 (NCT04706286) | Chong Kun Dang Pharmaceutical | 2021-02-18 |
| Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates (NCT04764851) | Emalex Biosciences Inc. | 2021-02-18 |
| 1a/1b Study of OPT101 First in Human Study Assessing Safety and Tolerability of 15-mer Peptide. (NCT04589403) | Op-T LLC | 2021-02-18 |
| Dose Escalation Study Assessing the Safety and Immune Response of PPV-06 Vaccine (NCT04447898) | Peptinov SAS | 2021-02-18 |
| Phase I/II Trial of S64315 Plus Azacitidine in Acute Myeloid Leukaemia (NCT04629443) | Institut de Recherches Internationales Servier | 2021-02-17 |
| TENDU Vaccine in Patients With Relapse After Primary Radical Prostatectomy (NCT04701021) | Ultimovacs ASA | 2021-02-17 |
| The Use of Nanoparticles to Guide the Surgical Treatment of Prostate Cancer (NCT04167969) | Memorial Sloan Kettering Cancer Center | 2021-02-17 |
| A Phase I Clinical Trial to Investigate the Safety, Tolerability, and Pharmacokinetic Characteristics of TT-01025-CL in Healthy Subjects (NCT04730050) | LG Chem | 2021-02-17 |
| Dose-Escalation and Dose-Expansion Study of ZX-101A in Patients With Relapsed/Resistant or Refractory Advanced Hematologic Malignancies (NCT04504708) | Hangzhou Zenshine Pharmaceuticals Co., Ltd. | 2021-02-17 |
| A First-in-human Single Ascending Dose/Multiple Ascending Dose Study of ENN0403 in Healthy Subjects (NCT05506540) | EnnovaBio | 2021-02-17 |
| AZD4573 in Novel Combinations With Anti-cancer Agents in Patients With Advanced Blood Cancer (NCT04630756) | AstraZeneca | 2021-02-17 |
| Study to Compare How the Body Absorbs, Distributes and Excretes the Drug Selitrectinib (BAY2731954) Given as Two Different Tablet Formulations or as Liquid Formulations Including the Effect of Food on the Absorption, Distribution or Excretion of the Different Formulations in Healthy Participants (NCT04771390) | Bayer | 2021-02-16 |
| Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of NIO752 in Progressive Supranuclear Palsy (NCT04539041) | Novartis Pharmaceuticals | 2021-02-16 |
| Safety and Immunogenicity of GX-19N, a COVID-19 Preventive DNA Vaccine in Elderly Individuals (NCT04915989) | Genexine, Inc. | 2021-02-16 |
| Evaluation the Safety and Efficacy of Cilostazol in Treatment of Patients With Fatty Liver Disease (NCT04761848) | Sadat City University | 2021-02-16 |
| The AMPK Modulator Metformin as a Novel Adjunct to Conventional Therapy in Patients With Knee Osteoarthritis (NCT04767841) | Sadat City University | 2021-02-16 |
| A Study to Assess Single and Multiple Doses of IkT-148009 in Healthy Elderly Participants and Parkinson's Patients (NCT04350177) | ABLi Therapeutics, Inc. | 2021-02-16 |
| MK-1942/Donepezil Interactions in Participants With Alzheimer's Disease (MK-1942-005) (NCT04308304) | Merck Sharp & Dohme LLC | 2021-02-16 |
| Oncolytic Virus (OVV-01) Injection in the Treatment of Patients With Advanced Solid Tumors (NCT04787003) | North China Petroleum Bureau General Hospital | 2021-02-16 |
| Neoadjuvant Immunotherapy With Durvalumab (MEDI4736) in Non-Surgical Early Stage or Locally Advanced Non-Small Cell Lung Cancer (NSCLC) Followed by Radical Radiotherapy or Chemoradiotherapy (NCT05267392) | Instituto Portugues de Oncologia, Francisco Gentil, Porto | 2021-02-16 |
| A Study of Different Forms of TAK-994 in Healthy Adults (NCT04745767) | Takeda | 2021-02-16 |
| BMS-986325 in Healthy Participants and Participants With Primary Sjögren's Syndrome (NCT04684654) | Bristol-Myers Squibb | 2021-02-16 |
| A Study Evaluating the Relative Bioavailability of Lofexidine Granules for Reconstitution Compared to LUCEMYRA (Lofexidine) Tablets and the Effect of Food on the Bioavailability of the Lofexidine Granules for Reconstitution (NCT04188730) | USWM, LLC (dba US WorldMeds) | 2021-02-16 |
| An Open Study of the Safety and Pharmacokinetics of a Drug for the Emergency Prevention of Ebola Virus Disease (NCT04717830) | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | 2021-02-15 |
| A Study to Investigate the Safety and Pharmacokinetic/Pharmacodynamic Characteristics of HSG4112 (NCT04703764) | Glaceum | 2021-02-15 |
| DNX-2440 for Resectable Colorectal Liver Metastasis (NCT04714983) | DNAtrix, Inc. | 2021-02-15 |
| Study of Amblyomin-X in Advanced Solid Tumor (NCT03120130) | União Química Farmacêutica Nacional S/A | 2021-02-15 |
| Pilot Study to Investigate the Safety and Feasibility of AntiRetroviral Therapy for Alzheimer's Disease (NCT04552795) | The University of Texas Health Science Center at San Antonio | 2021-02-15 |
| Effects of (Licochalcone A) and Paclitaxel on Human Oral Squamous Cell Carcinoma Cell Line (NCT03292822) | Cairo University | 2021-02-15 |
| d-Limonene +Radiation +PlatinumBasedChemo for Xerostomia Prevention in LocallyAdvanced HNSCC (NCT04392622) | Stanford University | 2021-02-15 |
| SYN-004 Safety and Tolerability in Allo-HCT Subjects (NCT04692181) | Theriva Biologics, Inc. | 2021-02-15 |
| Study to Evaluate the Effects of Single Ascending Oral Doses of ACD856 on Safety, Tolerability and Pharmacokinetics (NCT05077631) | AlzeCure Pharma | 2021-02-15 |
| A Study of the Safety of and Immune Response to Varying Doses of a Vaccine Against COVID-19 in Healthy Adults (NCT04758962) | GlaxoSmithKline | 2021-02-15 |
| A Study of Lasmiditan in Healthy Volunteers (NCT04749914) | Eli Lilly and Company | 2021-02-15 |
| Bioequivalence Study of Aripiprazole in Healthy Adult Subjects Under Fasting Condition (NCT05532254) | Future University in Egypt | 2021-02-14 |
| Bioequivalence Study of Two Formulations of Rivaroxaban Tablets 10 mg in Healthy Male Volunteers in Fasting Conditions (NCT04753489) | Pharmtechnology LLC | 2021-02-13 |
| Safety and Preliminary Efficacy of Donor-derived Anti-leukemia Cytotoxic T Lymphocytes for the Prevention of Leukemia Relapse in Children Given Haploidentical Hematopoietic Stem Cell Transplantation (NCT06865352) | Fondazione IRCCS Policlinico San Matteo di Pavia | 2021-02-13 |
| A Study of TAK-019 in Healthy Japanese Adults (COVID-19) (NCT04712110) | Takeda | 2021-02-12 |
| Surufatinib Renal Impairment Study (NCT04755088) | Hutchison Medipharma Limited | 2021-02-12 |
| Pembrolizumab and Hypofractionated Stereotactic Radiotherapy in Patients With Malignant Pleural Mesothelioma (NCT04166734) | Royal Marsden NHS Foundation Trust | 2021-02-12 |
| Surufatinib Hepatic Impairment Study (NCT04755075) | Hutchison Medipharma Limited | 2021-02-12 |
| Mesenchymal Stromal Cells for the Treatment of SARS-CoV-2 Induced Acute Respiratory Failure (COVID-19 Disease) (NCT04345601) | Baylor College of Medicine | 2021-02-12 |
| Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer (NCT04703101) | Jonsson Comprehensive Cancer Center | 2021-02-11 |
| Maternal Betaine Supplementation During Breastfeeding (NCT04633044) | Fundació Sant Joan de Déu | 2021-02-11 |
| STUDY OF PF-07321332 IN HEALTHY PARTICIPANTS (NCT04756531) | Pfizer | 2021-02-11 |
| A Trial of SHR8735 in Healthy Subjects (NCT04701216) | Atridia Pty Ltd. | 2021-02-11 |
| First Clinical Study of the Safety and Blood Levels of a Human Monoclonal Antibody (2217LS) Against Lyme Disease Bacteria in Healthy People (NCT04863287) | MassBiologics | 2021-02-11 |
| A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 706321 in the Blood (NCT04714073) | Boehringer Ingelheim | 2021-02-11 |
| A Study to Assess the Pharmacokinetics of Certolizumab Pegol in Adults With Active Rheumatoid Arthritis (NCT04740814) | UCB Biopharma SRL | 2021-02-11 |
| Fibrosis and the Fontan (NCT04901975) | Children's Hospital of Philadelphia | 2021-02-11 |
| A Clinical Pharmacology Study to Evaluate the Effect of GYM329 on Disuse Muscle Atrophy in Healthy Volunteer (NCT04708847) | Chugai Pharmaceutical | 2021-02-10 |
| Study of XL102 as Single-Agent and Combination Therapy in Subjects With Solid Tumors (QUARTZ-101) (NCT04726332) | Exelixis | 2021-02-10 |
| NBTXR3 and Radiation Therapy for the Treatment of Inoperable Recurrent Non-small Cell Lung Cancer (NCT04505267) | M.D. Anderson Cancer Center | 2021-02-10 |
| Home-administered tDCS for Treatment of Depression (NCT04781127) | Soterix Medical | 2021-02-10 |
| Study to Evaluate the Safety and Efficacy of VIRAZOLE® in Hospitalized Adult Participants With Respiratory Distress Due to COVID-19 (NCT04551768) | Bausch Health Americas, Inc. | 2021-02-10 |
| Study to Evaluate the Safety and Efficacy of IPN59011 in Improving the Appearance of Moderate to Severe Upper Facial Lines. (NCT04736745) | Ipsen | 2021-02-10 |
| Study of a Single Intravenous (IV) Dose of MK-3402 in Participants With Impaired Renal Function and in Healthy Controls (MK-3402-004) (NCT04678505) | Merck Sharp & Dohme LLC | 2021-02-10 |
| Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Adults With T-allo10 Cells Addback (NCT04640987) | Porteus, Matthew, MD | 2021-02-10 |
| A Clinical Trial of COVAC-2 in Healthy Adults (NCT04702178) | University of Saskatchewan | 2021-02-10 |
| SAR439459 and Cemiplimab for the Treatment of Advanced or Unresectable Solid Tumors, Strategic Alliance, TACTIC TRIAL (NCT04729725) | M.D. Anderson Cancer Center | 2021-02-09 |
| Retina is a Marker for Cerebrovascular Heath (NCT04753970) | Mayo Clinic | 2021-02-09 |
| Evaluation of Oral ORIN1001 in Subjects With Idiopathic Pulmonary Fibrosis (IPF) (NCT04643769) | Orinove, Inc. | 2021-02-09 |
| A Six Week Pharmacokinetic Study of TP-03 in Healthy Subjects (NCT05138861) | Tarsus Pharmaceuticals, Inc. | 2021-02-09 |
| Safety, Tolerability and Efficacy of Amorphous Calcium Carbonate (ACC) Compared to Placebo and Best Available Care (BAT), for the Treatment of Moderate to Severe COVID-19 Patients. (NCT04900337) | Amorphical Ltd. | 2021-02-09 |
| A Social Network AOD Intervention for Homeless Youth Transitioning to Housing (NCT04637815) | RAND | 2021-02-09 |
| Pharmacokinetics, Safety, and Efficacy of ASTX727 in Combination With Venetoclax in Acute Myeloid Leukemia (AML) (NCT04657081) | Taiho Oncology, Inc. | 2021-02-09 |
| Study to Evaluate Safety and Activity of TRL1068 in Prosthetic Joint Infections (NCT04763759) | Trellis Bioscience LLC | 2021-02-08 |
| Pharmacokinetic Evaluation of Intranasal Nalmefene (NCT04759768) | Opiant Pharmaceuticals Inc | 2021-02-08 |
| Low-Dose Selinexor and Choline Salicylate for Non-Hodgkin or Hodgkin Lymphoma, Histiocytic/Dendritic Cell Neoplasm, or Relapsed or Refractory Multiple Myeloma (NCT04640779) | Mayo Clinic | 2021-02-08 |
| Clinical Trial to Evaluate the PK and Safety of BCD-201 and Keytruda® in Patients With Advanced Malignancies (NCT05739006) | Biocad | 2021-02-08 |
| A Study of KB-0742 in Participants With Relapsed or Refractory Solid Tumors Including Platinum Resistant High Grade Serous Ovarian Cancer (HGSOC) (NCT04718675) | Kronos Bio | 2021-02-08 |
| Neurobiological Drivers of Mobility Resilience: The Dopaminergic System (NCT04325503) | University of Michigan | 2021-02-08 |
| A Trial to Compare the Pharmacokinetics of Tralokinumab in Healthy Subjects (NCT04674826) | LEO Pharma | 2021-02-08 |
| Study to Test OBI-3424 in Patients With T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LBL) (NCT04315324) | SWOG Cancer Research Network | 2021-02-08 |
| F573 Ia Clinical Trial (NCT04820049) | Beijing Continent Pharmaceutical Co, Ltd. | 2021-02-08 |
| STARS (Smoking Treatment And Remote Sampling) Study (NCT04525755) | Medical University of South Carolina | 2021-02-08 |
| A Study on Ketoprofen Lysine Salt (KLS) + Gabapentin (GABA) vs KLS to Investigate Their Pharmacodynamic in Healthy Males (NCT04802967) | Dompé Farmaceutici S.p.A | 2021-02-08 |
| Safety, Tolerability and Pharmacokinetics of TWP-101 in Patients With Advanced Melanoma and Urothelial Carcinoma (NCT04871334) | Shandong TheraWisdom Biopharma Co., Ltd. | 2021-02-07 |
| Pharmacokinetics of Clozapine and Norclozapine and the Effect of Pantoprazole (NCT07262736) | Universiti Sains Malaysia | 2021-02-06 |
| A Study in Healthy Japanese Men to Test How Well Different Doses of BI 764198 Are Tolerated (NCT04665700) | Boehringer Ingelheim | 2021-02-06 |
| Allogeneic CD19 CAR-T Cells for the Treatment of Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia (NCT05164042) | Shenzhen University General Hospital | 2021-02-05 |
| A Single Dose-escalation Study to Evaluate the Safety and Pharmacokinetics of RBD1016 (NCT04685564) | Suzhou Ribo Life Science Co. Ltd. | 2021-02-05 |
| Allogeneic CD19 CAR-T Cells for the Treatment of Relapsed/Refractory B-cell Lymphoma (NCT05143112) | Shenzhen University General Hospital | 2021-02-05 |
| Treatment of Malignant Tumors With NK Cell (NCT05143125) | Shenzhen University General Hospital | 2021-02-05 |
| A Study to Evaluate the My Hematology Oncology Patient Experience (MyHOPE™) For Multiple Myeloma (MM) Digital Care Network in Patients With MM (NCT04730505) | Celgene | 2021-02-04 |
| Neoadjuvant Therapy in Biliary Adenocarcinoma (NCT04480190) | Jordan Kharofa | 2021-02-04 |
| SPL026 (DMT Fumarate) in Healthy Subjects and MDD Patients (NCT04673383) | Small Pharma Ltd | 2021-02-04 |
| Testing the Addition of an Anti-cancer Drug, Navtemadlin, to the Usual Treatments (Cytarabine and Idarubicin) in Patients With Acute Myeloid Leukemia (NCT04190550) | National Cancer Institute (NCI) | 2021-02-04 |
| A Study to Compare SB17 (Proposed Ustekinumab Biosimilar) to European Union (EU) Sourced Stelara and United States of America (US) Sourced Stelara in Healthy Subjects (NCT04772274) | Samsung Bioepis Co., Ltd. | 2021-02-04 |
| Trial Combining Pembrolizumab and Cesium 131 Brachytherapy With Salvage Surgery in HNSCC (NCT04340258) | University of Cincinnati | 2021-02-04 |
| Safety, Tolerability, and Immunogenicity of a Polyvalent Pneumococcal Conjugate Vaccine (V116) in Japanese Adults (V116-002) (NCT04665050) | Merck Sharp & Dohme LLC | 2021-02-04 |
| Pharmacokinetics, Pharmacodynamics and Safety of LY01005 in Patients With Prostate Cancer Compared to ZOLADEX® (NCT05140512) | Luye Pharma Group Ltd. | 2021-02-04 |
| Website Smoking Cessation Intervention for the Promotion of Smoking Cessation in Low-Income Veterans (NCT04502524) | Fred Hutchinson Cancer Center | 2021-02-03 |
| Camostat With Bicalutamide for COVID-19 (NCT04652765) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2021-02-03 |
| A Study of JNJ-64300535 in Healthy Participants (NCT04736147) | Janssen Research & Development, LLC | 2021-02-03 |
| An Investigational Study of SHR3680 in Participants With Mild to Moderate Liver Impairment and Healthy Participants (NCT04631549) | Jiangsu HengRui Medicine Co., Ltd. | 2021-02-03 |
| Safety and Immunogenicity Study of SARS-CoV-2 Nanoparticle Vaccine (GBP510) Adjuvanted With or Without AS03 (COVID-19) (NCT04750343) | SK Bioscience Co., Ltd. | 2021-02-03 |
| Study to Evaluate Safety, Tolerability, and the PK Profile of TBI-223 in Healthy Subjects (NCT04865536) | Global Alliance for TB Drug Development | 2021-02-03 |