| A Study to Learn How Safe BAY2666605 is, How it Affects the Body, How it Moves Into, Through and Out of the Body, the Maximum Amount That Can be Given and Its Action Against Tumors in Adult Participants With Skin Cancer That Has Spread to Other Parts of the Body and Other Types of Advanced Cancer (NCT04809805) | Bayer | 2021-04-15 |
| A First-in-Human, Phase 1 Study of SY-4798 in Patients With Advanced Solid Tumor (NCT05498519) | Shouyao Holdings (Beijing) Co. LTD | 2021-04-15 |
| Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia (NCT04159103) | ModernaTX, Inc. | 2021-04-15 |
| A Clinical Study Evaluating Nivolumab-containing Treatments in Patients With Advanced Non-small Cell Lung Cancer After Failing Previous PD-1/(L)1 Therapy and Chemotherapy (NCT04151563) | Bristol-Myers Squibb | 2021-04-15 |
| Nab-paclitaxel Based TPX Neoadjuvant Chemotherapy for NPC Patients: a Dose-escalation Study (NCT04850235) | Sun Yat-sen University | 2021-04-15 |
| Decitabine-primed Tandem CD19/CD20 CAR T Cells Treatment in r/r B-NHL (NCT04697940) | Han weidong | 2021-04-15 |
| A Prospective Multi-dose Study of Apixaban in Subjects With Nephrotic Syndrome (NCT04278729) | University of North Carolina, Chapel Hill | 2021-04-14 |
| A Study to Assess the Bioequivalence of Ustekinumab by Two Different Injection Devices in Healthy Participants (NCT04816513) | Janssen Research & Development, LLC | 2021-04-14 |
| Testing the Addition of an Anti-cancer Drug, Berzosertib (M6620, VX-970), to the Usual Treatments (Carboplatin and Gemcitabine) and to Pembrolizumab for Patients With Advanced Squamous Cell Non-small Cell Lung Cancer (NCT04216316) | National Cancer Institute (NCI) | 2021-04-14 |
| Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies (NCT04902040) | M.D. Anderson Cancer Center | 2021-04-14 |
| A Dose Escalation and Food Effect Study of SKLB1028 in Healthy Subjects (NCT05109663) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2021-04-14 |
| Safety, Tolerability & Pharmacokinetics Study of CNTX-6016 in Healthy Subjects and Subjects With PDN (NCT04857957) | Centrexion Therapeutics | 2021-04-14 |
| Tazemetostat and Pembrolizumab in Patients With Pembrolizumab- or Nivolumab-Resistant, Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma (NCT04624113) | Washington University School of Medicine | 2021-04-14 |
| A Study of JNJ-70033093 (Milvexian) in Healthy Adult Participants (NCT04844424) | Janssen Research & Development, LLC | 2021-04-14 |
| A Study Investigate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Response of SLN124 in Adults With Alpha/Beta-thalassaemia and Very Low- and Low-risk Myelodysplastic Syndrome (NCT04718844) | Silence Therapeutics plc | 2021-04-14 |
| Safety and Efficacy of XT-150 for Treatment of Neuropathic Pain (NCT04466410) | Xalud Therapeutics, Inc. | 2021-04-14 |
| Phase 1 Study to Assess Safety, Tolerability, PD, PK, Immunogenicity of IV NTR-441 Solution in Healthy Volunteers and COVID-19 Patients (NCT04941183) | Neutrolis | 2021-04-14 |
| Autologous HBV-specific T Cell Receptor Engineered T Cells (TCR-T) in Patients With HBV-related Advanced HCC (NCT05339321) | Peking Union Medical College Hospital | 2021-04-14 |
| Safe Accelerated Venetoclax Escalation in CLL (NCT04843904) | Dana-Farber Cancer Institute | 2021-04-14 |
| Study to Evaluate Absorption, Metabolism, and Excretion, of TAK-994 in 6 Healthy Male Adults (NCT04833049) | Takeda | 2021-04-14 |
| A Study of GNC-039, a Tetra-specific Antibody, in Participants With Relapsed/Refractory or Metastatic Solid Tumors (NCT04794972) | Sichuan Baili Pharmaceutical Co., Ltd. | 2021-04-14 |
| A Study to Evaluate the Safety, Tolerability, Drug Levels, and Drug Effects of BMS-986308 in Healthy Participants (NCT04763226) | Bristol-Myers Squibb | 2021-04-14 |
| Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion (NCT04794699) | IDEAYA Biosciences | 2021-04-14 |
| Study of ET140203 T Cells in Adults With Advanced Hepatocellular Carcinoma (ARYA-1) (NCT04502082) | Eureka Therapeutics Inc. | 2021-04-14 |
| Clinical Study of VG161 in Subjects With Advanced Malignant Solid Tumors (NCT04758897) | CNBG-Virogin Biotech (Shanghai) Ltd. | 2021-04-14 |
| 68Ga-DOTA-FAPI and 177Lu-DOTA-FAPI Theranostic Pair in Patients With Various Types of Cancer (Locally Advanced or Metastatic Cancer) (NCT04849247) | The First Affiliated Hospital of Xiamen University | 2021-04-13 |
| Human Umbilical Cord Mesenchymal Stem Cell(UC-MSC)Delayed Renal Chronic Kidney Disease(CKD3、4 ) (NCT05512988) | Tongji Hospital | 2021-04-13 |
| A Study in Healthy Subjects to Assess Drug Availability of 4 Different Formulations of Verinurad and Allopurinol (NCT04550234) | AstraZeneca | 2021-04-13 |
| Phase 1 Oral QPX7831 SAD and MAD in Healthy Adults (NCT04578873) | Qpex Biopharma, Inc. | 2021-04-13 |
| Non-Opioid Pain Medications After Intracapsular Adenotonsillectomy (NCT04791761) | David Chi, MD | 2021-04-13 |
| Study of Aldafermin (NGM282) in Healthy Adult Male Japanese and Non-Japanese Subjects (NCT04828265) | NGM Biopharmaceuticals, Inc | 2021-04-13 |
| Assessment of the Pharmacodynamic and Pharmacokinetic Interaction of Remimazolam and Remifentanil (NCT04670471) | Paion UK Ltd. | 2021-04-13 |
| Study of FCN-011 in Patients With Advanced Solid Tumor（Phase I）and NTRK Fusion Positive Advanced Solid Tumor （Phase II） (NCT04687423) | Fochon Pharmaceuticals, Ltd. | 2021-04-13 |
| Single Ascending Dose Study of CM326 in Healthy Volunteers (NCT04842201) | Keymed Biosciences Co.Ltd | 2021-04-13 |
| A Study of MPT-0118 in Subjects With Advanced or Metastatic Refractory Solid Tumors (NCT04859777) | Monopteros Therapeutics Inc. | 2021-04-13 |
| Placebo-Corrected Effects of Therapeutic Dose (100 mg) and Supratherapeutic Dose (300 mg) of ITF2357 (Givinostat) and Moxifloxacin on QT/QTC Interval (NCT04821063) | Italfarmaco | 2021-04-13 |
| APG-2575 Monotherapy or in Combination With Lenalidomide/DXMS in Subjects With Relapsed or Refractory Multiple Myeloma (NCT04674514) | Ascentage Pharma Group Inc. | 2021-04-13 |
| Study of Radiolabeled ALXN2050 in Healthy Adult Males (NCT04609670) | Alexion Pharmaceuticals, Inc. | 2021-04-12 |
| Rigosertib for RDEB-SCC (NCT03786237) | Prof. Johann Bauer | 2021-04-12 |
| A Phase 1/2 Clinical Trial to Evaluate the Safety, Tolerability, Dosimetry, and Anti-tumor Activity of Ga-68-NGUL / Lu-177-DGUL in Patients With Metastatic Castration-resistant Prostate Cancer (mCRPC) Refractory to Standard Therapy (NCT05547061) | Cellbion Co., Ltd. | 2021-04-12 |
| A Phase I Study to Evaluate the Safety, Tolerability and Pharmacokinetics of JS004 in Advanced Solid Tumors (NCT04773951) | Shanghai Junshi Bioscience Co., Ltd. | 2021-04-12 |
| Safety and Preliminary Efficacy of MBS8(1V270) in Cancer Patients With Advanced Solid Tumours (NCT04855435) | MonTa Biosciences ApS | 2021-04-12 |
| Gentulizumab in Patients With Advanced Solid Malignancies and Non-Hodgkin Lymphoma (NCT05221385) | Changchun GeneScience Pharmaceutical Co., Ltd. | 2021-04-12 |
| Safety and Efficacy Study of Human Umbilical Cord-Derived Mesenchymal Stem Cells(BC-U001) for Rheumatoid Arthritis (NCT04971980) | Beijing Baylx Biotech Co., Ltd. | 2021-04-12 |
| Safety and Immunogenicity of an Intranasal RSV Vaccine Expressing SARS-CoV-2 Spike Protein (COVID-19 Vaccine) in Adults (NCT04798001) | Meissa Vaccines, Inc. | 2021-04-12 |
| A Study to Assess the Bioequivalence of Fixed Dose Combination of Dapagliflozin/Metformin XR Relative to Co-administration of the Individual Components in Healthy Chinese Subjects. (NCT04856007) | AstraZeneca | 2021-04-12 |
| A Study to Evaluate the Skin Irritation Potential of PBI-100 Topical Cream in Healthy Participants (NCT04882631) | Pyramid Biosciences | 2021-04-12 |
| Modified Ketogenic Diet and Ketamine for Anorexia Nervosa (NCT04714541) | Homeostasis Therapeutics, LLC | 2021-04-12 |
| A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH (NCT04764474) | Hutchmed | 2021-04-12 |
| Assess the Safety, Tolerability, PK and Anti-tumor Efficacy of DZD2269 in Patients With MCRPC (NCT04634344) | Dizal Pharmaceuticals | 2021-04-12 |
| Study of SAR444881 Administered Alone and in Combination With Other Therapeutics in Participants With Advanced Solid Tumors (NCT04717375) | Sanofi | 2021-04-11 |
| Bioequivalence Study of Two Formulations of Etoricoxib Tablets 120 mg in Healthy Volunteers Under Fasting Conditions (NCT04830579) | Pharmtechnology LLC | 2021-04-10 |
| Safety, Tolerability and Pharmacokinetics Study of CK-3773274 (NCT04783766) | Corxel Pharmaceuticals | 2021-04-10 |
| Cord Blood Derived Anti-CD19 CAR-Engineered NK Cells for B Lymphoid Malignancies (NCT04796675) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2021-04-10 |
| Safety and Immunogenicity of the rVSVΔG-ZEBOV-GP Ebola Virus Vaccine Candidate in Children Living in Lambaréné, Gabon (NCT05130398) | Centre de Recherche Médicale de Lambaréné | 2021-04-09 |
| A Study to Evaluate the Relative Bioavailability of E7386 Following Oral Administration of Targeted Release (TR) Tablets Compared to an E7386 Immediate Release (IR) Tablet in Healthy Adult Participants (NCT04840927) | Eisai Limited | 2021-04-09 |
| Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers (NCT04460937) | National Cancer Institute (NCI) | 2021-04-09 |
| Neoantigen-expanded Autologous Immune Cell Therapy (NCT05020119) | Chang Gung Memorial Hospital | 2021-04-09 |
| Comparison of the Extent to Which the Drug Given as Two Different Capsule Sizes Becomes Available to the Body (NCT04845841) | Bayer | 2021-04-09 |
| Bioavailability of Curcumin Capsules in Healthy Adult Subjects (NCT04972045) | The Affiliated Hospital of Qingdao University | 2021-04-09 |
| The Germinal Peptide Eye Drops in Healthy Volunteers in a Clinical Study (NCT03967548) | Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. | 2021-04-09 |
| Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery (NCT04997291) | University of Texas at Austin | 2021-04-09 |
| Fludarabine, Cytarabine, and Pegcrisantaspase for the Treament of Relapsed or Refractory Leukemia (NCT04526795) | M.D. Anderson Cancer Center | 2021-04-09 |
| Nasal Septum Perforation Treatment Using Tissue Engineered Cartilage Graft (NCT04633928) | University Hospital, Basel, Switzerland | 2021-04-09 |
| Clinical Study of ssCART-19 Cells in Patients With CD19 Positive Relapsed or Refractory Acute Lymphoblastic Leukemia (NCT04825496) | Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd | 2021-04-09 |
| Phase I/II Study of Enhanced CD33 CAR T Cells in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (NCT04835519) | Beijing Boren Hospital | 2021-04-08 |
| A Study of Irinotecan Liposome in Advanced Pancreatic Cancer (NCT04796948) | Jiangsu HengRui Medicine Co., Ltd. | 2021-04-08 |
| A Phase 1 Dose Escalation and Expansion Study Of SHR-1916 In Subjects With Locally Advanced Or Metastatic Solid Tumors (NCT04842630) | Jiangsu HengRui Medicine Co., Ltd. | 2021-04-08 |
| Evaluate the Safety, Tolerability, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of HLX71 (Recombinant Human Angiotensin-converting Enzyme 2-Fc Fusion Protein for COVID-19) in Healthy Adult Subjects (NCT04583228) | Hengenix Biotech Inc | 2021-04-08 |
| A Study of LNK01002 in Patients With Primary or Secondary Myelofibrosis,Polycythemia Vera or Acute Myeloid Leukemia (NCT04896112) | Lynk Pharmaceuticals Co., Ltd | 2021-04-08 |
| First in Human Study to Evaluate the Safety, Tolerability of HH30134 in Advanced Solid Tumors (NCT04746612) | Haihe Biopharma Co., Ltd. | 2021-04-08 |
| A Study to Evaluate the Effect of Multiple Doses of Itraconazole, Phenytoin, and Paroxetine on the Single-Dose Pharmacokinetics of Poziotinib in Healthy Adult Participants (NCT04981704) | Spectrum Pharmaceuticals, Inc | 2021-04-08 |
| PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates (NCT04887194) | Mirati Therapeutics Inc. | 2021-04-08 |
| RTX-321 Monotherapy in Patients With HPV 16+ Tumors (NCT04672980) | Rubius Therapeutics | 2021-04-08 |
| Study to Evaluate the Safety and Efficacy of Teropavimab and Zinlirvimab in Combination With Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection (NCT04811040) | Gilead Sciences | 2021-04-08 |
| Selinexor and Pembrolizumab for the Treatment of Cisplatin-Ineligible or Cisplatin-Refractory Locally Advanced or Metastatic Urothelial Carcinoma (NCT04856189) | Mamta Parikh | 2021-04-08 |
| Study to Evaluate of EXG34217 in Patients With Telomere Biology Disorders With Bone Marrow Failure (NCT04211714) | Elixirgen Therapeutics, Inc. | 2021-04-08 |
| Food Effect and Relative Bioavailability Study of Rilzabrutinib in Healthy Participants (NCT04748926) | Principia Biopharma, a Sanofi Company | 2021-04-07 |
| CANA/Met in Non-diabetic Women With PCOS (NCT04973891) | Shengjing Hospital | 2021-04-07 |
| A Clinical Trial of a Prophylactic Plasmid DNA Vaccine for COVID-19 [Covigenix VAX-001] in Adults (NCT04591184) | Entos Pharmaceuticals Inc. | 2021-04-07 |
| Dose Escalation of RMC-5552 Monotherapy in Relapsed/Refractory Solid Tumors (NCT04774952) | Revolution Medicines, Inc. | 2021-04-07 |
| Fecal Microbiota Transplantation by Oral Capsules for Hepatic Encephalopathy Treatment (NCT06368895) | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 2021-04-07 |
| MIcroglial Colony Stimulating Factor-1 Receptor (CSF1R) in Alzheimer's Disease (NCT04121208) | University of Oxford | 2021-04-07 |
| Study of the Influence of Liver Function on Blood Concentrations of Runcaciguat in Participants With Different Degrees of Liver Impairment (NCT04820621) | Bayer | 2021-04-07 |
| The Effect of Itraconazole and Rifampicin on the Pharmacokinetics of SH-1028 (NCT04808648) | Nanjing Sanhome Pharmaceutical, Co., Ltd. | 2021-04-06 |
| A Study of Vonoprazan in Adults With Helicobacter Pylori (NCT04753437) | Takeda | 2021-04-06 |
| Pertussis Acellular Vaccine Adjuvanted With TQL1055 (NCT04793620) | Adjuvance Technologies, Inc. | 2021-04-06 |
| A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Moderate to Severe Upper Facial Lines (NCT04821089) | Ipsen | 2021-04-06 |
| Anti-COVID19 AKS-452 Fusion Protein Vaccine - ACT Study (NCT04681092) | University Medical Center Groningen | 2021-04-06 |
| Testing the Addition of an Anti-cancer Drug, Hu5F9-G4 (Magrolimab), to the Usual Chemotherapy Treatment (Mogamulizumab) in T-Cell (a Type of Immune Cell) Lymphoma That Has Returned After Treatment or Does Not Respond to Treatment (NCT04541017) | National Cancer Institute (NCI) | 2021-04-06 |
| A Study of Toripalimab Injection (JS001) + Cetuximab in Treatment of Advanced Head and Neck Squamous Cell Cancer (NCT04856631) | Shanghai Junshi Bioscience Co., Ltd. | 2021-04-06 |
| Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment (NCT04617522) | Gilead Sciences | 2021-04-06 |
| A Drug-Drug Interaction Study Between PF-06882961 and PF-06865571 in Healthy Adult Participants and Overweight Adults or Adults With Obesity Who Are Otherwise Healthy (NCT04839393) | Pfizer | 2021-04-05 |
| PHASE 1 SARS-COV-2-Spike-Ferritin-Nanoparticle (SpFN) Vaccine With ALFQ Adjuvant for Prevention of COVID-19 (NCT04784767) | U.S. Army Medical Research and Development Command | 2021-04-05 |
| Behavioral Dietary Intervention for the Improvement of Bladder Cancer Survivorship (NCT04548193) | Roswell Park Cancer Institute | 2021-04-05 |
| Single and Multiple Ascending Dose Study With EP395 (NCT04819854) | EpiEndo Pharmaceuticals | 2021-04-05 |
| Study to Evaluate the Effects of Itraconazole and Rifampin on the Pharmacokinetics of ASC40 in Healthy Subjects (NCT04843449) | Ascletis Pharmaceuticals Co., Ltd. | 2021-04-04 |
| Bioavailability and Food Effect Study of Two Formulations of TAK-906 (NCT04831502) | Takeda | 2021-04-02 |
| Phase 1/2 Study of BBT-176 in Advanced NSCLC With Progression After EGFR TKI Treatment (NCT04820023) | Bridge Biotherapeutics, Inc. | 2021-04-02 |
| A Study to Investigate Safety and Tolerability of SH3809 Tablet in Patients With Advanced Solid Tumors (NCT04843033) | Nanjing Sanhome Pharmaceutical, Co., Ltd. | 2021-04-02 |