| Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Dose of TT-00920 in Healthy Subjects (NCT05043792) | TransThera Sciences (Nanjing), Inc. | 2021-08-19 |
| Mass Balance Recovery, Metabolite Profile, and Metabolite Identification of [14C]-Paxalisib in Healthy Male Subjects (NCT05012670) | Kazia Therapeutics Limited | 2021-08-18 |
| [18F]PT2385 PET/CT in Patients With Renal Cell Carcinoma (NCT04989959) | Orhan Kemal Oz | 2021-08-18 |
| IMM2510, a PD-L1 and VEGF Bispecific Fusion Protein, in Patients With Advanced Solid Tumors (NCT05972460) | ImmuneOnco Biopharmaceuticals (Shanghai) Inc. | 2021-08-18 |
| A Personalized Neoantigen Cancer Vaccine in Treatment Naïve, Asymptomatic Patients With IGHV Unmutated CLL. (NCT03219450) | Dana-Farber Cancer Institute | 2021-08-18 |
| Exploratory Study to Assess Delivery of LMN-201 Components Via Enteric Capsules in the Gut of Individuals With Ostomies (NCT04893239) | Lumen Bioscience, Inc. | 2021-08-18 |
| Study to Test the Safety and Tolerability of PF-07257876 in Participants With Selected Advanced Tumors. (NCT04881045) | Pfizer | 2021-08-18 |
| Study of Denikitug (GS-1811) Given Alone or With Zimberelimab in Adults With Advanced Solid Tumors (NCT05007782) | Gilead Sciences | 2021-08-18 |
| Single Dose Absorption, Distribution, Metabolism, and Excretion Study of [14C]-CORT113176 in Healthy Male Participants (NCT04990310) | Corcept Therapeutics | 2021-08-18 |
| Study to Assess a Booster Dose of GBS-NN/NN2 Vaccine (NCT05005247) | Minervax ApS | 2021-08-17 |
| Safety and Clinical Activity of Nivatrotamab in Relapsed/Recurrent Metastatic Small-cell Lung Cancer (NCT04750239) | Y-mAbs Therapeutics | 2021-08-17 |
| The Safety and Pharmacokinetics Study of TAKC-02 Inhalation Solution in Healthy Adult Males. (NCT05018533) | TAK-Circulator Co. | 2021-08-17 |
| FHD-609 in Subjects With Advanced Synovial Sarcoma or Advanced SMARCB1-Loss Tumors (NCT04965753) | Foghorn Therapeutics Inc. | 2021-08-17 |
| A Clinical Safety Study on AT-100 in Treating Adults With Severe COVID-19 Infection or Severed Community Acquired Pneumonia (NCT04659122) | Airway Therapeutics, Inc. | 2021-08-17 |
| Tolerogenic Dendritic Cell Therapy for Rheumatoid Arthritis (NCT05251870) | UMC Utrecht | 2021-08-17 |
| A Safety and Efficacy Study Evaluating ET-01 in Subjects with Transfusion Dependent Β-Thalassaemia (NCT04925206) | EdiGene (GuangZhou) Inc. | 2021-08-17 |
| PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease (NCT04396873) | National Institute of Mental Health (NIMH) | 2021-08-17 |
| A Single-Dose Study of LY3471851 in Healthy Participants (NCT04998487) | Nektar Therapeutics | 2021-08-16 |
| Dose Escalation and Expansion Study of SAR443216 in Participants With Relapsed/Refractory HER2 Expressing Solid Tumors (NCT05013554) | Sanofi | 2021-08-16 |
| Administration of L. Paracasei 28.4 as an Adjunct to the Treatment of Periodontitis (NCT05107622) | Universidade Estadual Paulista Júlio de Mesquita Filho | 2021-08-16 |
| A Study to Compare the Pharmacokinetics of Two Different Tablets of Sotorasib in Healthy Participants (NCT05048784) | Amgen | 2021-08-16 |
| A Study to Test Three Experimental HIV Vaccines in Healthy Adults. (NCT04553016) | University of Oxford | 2021-08-16 |
| Safety and Immunogenicity Study of Recombinant Protein RBD Candidate Vaccine Against SARS-CoV-2 in Adult Healthy Volunteers (COVID-19) (NCT05007509) | Laboratorios Hipra, S.A. | 2021-08-16 |
| A Phase I Study of TS-172 in Healthy Adult Subjects (Single and Multiple Doses) (NCT04979572) | Taisho Pharmaceutical Co., Ltd. | 2021-08-16 |
| A Clinical Trial to Evaluate Drug-drug Interactions and Safety Between "BR1015-1" and "BR1015-2" in Healthy Volunteers (NCT05097794) | Boryung Pharmaceutical Co., Ltd | 2021-08-16 |
| Reducing Hypoxia in Patients With Coronavirus Disease (COVID-19) Using Topotecan With Standard of Care (NCT05083000) | National University Hospital, Singapore | 2021-08-16 |
| Allogeneic Mesenchymal Human Stem Cell Infusion Therapy for Endothelial DySfunctiOn in Diabetic Subjects With Symptomatic Ischemic Heart Disease. (ACESO-IHD) (NCT04776239) | Joshua M Hare | 2021-08-16 |
| PK Study of Liquid Formulation of BIO89-100 in Subjects With NASH With Compensation Cirrhosis (NCT05022693) | 89bio, Inc. | 2021-08-16 |
| Tolerability and Safety of Vemurafenib, Cetuximab Combined With Camrelizumab for BRAF V600E-mutated /MSS Metastatic Colorectal Cancer (NCT05019534) | West China Hospital | 2021-08-15 |
| The Pharmacokinetic and Pharmacodynamic Effects of Oral Cannabidiol (CBD) Under Acute and Chronic Exposure Conditions (NCT04283019) | Johns Hopkins University | 2021-08-15 |
| Heterologous Prime-boost Immunization with an Aerosolised Adenovirus Type-5 Vector-based COVID-19 Vaccine (Ad5-nCoV) After Priming with an Inactivated SARS-CoV-2 Vaccine (NCT05043259) | Jiangsu Province Centers for Disease Control and Prevention | 2021-08-14 |
| A Phase I Randomized, Double-Blind, Placebo-Controlled, Parallel Group Clinical Study of ICP-332 in Healthy Subjects (NCT05399030) | Beijing InnoCare Pharma Tech Co., Ltd. | 2021-08-14 |
| Study of PBI-0451 in Healthy Subjects. (NCT05011812) | Pardes Biosciences, Inc. | 2021-08-14 |
| Pilocarpine, Brimonidine, Oxymetazoline (PBO) Compound to Control Presbyopia Symptoms (NCT05006911) | Optall Vision | 2021-08-14 |
| NVP-1805 Compared to Coadministration of NVP-1805-R1 With NVP-1805-R2 in Healthy Adult Volunteers (NCT04905342) | NVP Healthcare | 2021-08-14 |
| A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Two Different Doses of Alpha1-Proteinase Inhibitor Subcutaneous (Human) 15% in Participants With Alpha1-Antitrypsin Deficiency (NCT04722887) | Grifols Therapeutics LLC | 2021-08-13 |
| Bioavailability of Bosutinib Administered as Capsule Contents Mixed With Applesauce or Yogurt Relative to Intact Capsules Under Fed Condition (NCT04916769) | Pfizer | 2021-08-13 |
| Safety, Tolerability and Pharmacokinetic of Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection (NCT05027373) | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 2021-08-13 |
| Fostamatinib for the Treatment of Lower-risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia Who Have Failed Therapy With Hypomethylating Agents (NCT05030675) | M.D. Anderson Cancer Center | 2021-08-13 |
| A Study of the Absorption, Metabolism, and Excretion of [14C]-Brensocatib Following a Single Oral Administration in Healthy Male Participants (NCT05652257) | Insmed Incorporated | 2021-08-13 |
| A Bioequivalence Study Between Fluticasone Propionate 100 mcg/Blister Oral Inhalation Powder/Respirent Pharmaceuticals vs. FLOVENT DISKUS® 100 mcg/Blister Oral Inhalation Powder /GSK in Healthy Volunteers Under Fasting Conditions (NCT05021887) | Respirent Pharmaceuticals Co Ltd. | 2021-08-13 |
| Testing the Addition of an Anticancer Drug, BAY 1895344, to the Usual Chemotherapy With FOLFIRI in Advanced or Metastatic Cancers of the Stomach and Intestines (NCT04535401) | National Cancer Institute (NCI) | 2021-08-13 |
| RVU120 (SEL120) in Patients with Relapse/Refractory Metastatic or Advanced Solid Tumors (NCT05052255) | Ryvu Therapeutics SA | 2021-08-13 |
| To Evaluate the Safety of Treating Autoimmune Diseases With Molecular Hydrogen Supplement (NCT05116215) | HoHo Biotech | 2021-08-13 |
| A Trial of AK117 (Anti-CD47 Antibody) in Patients With Acute Myeloid Leukemia (NCT04980885) | Akeso | 2021-08-13 |
| A Study to Investigate the Effect of Food on the Pharmacokinetics of IN-A002 Capsule in Healthy Male Subjects (NCT05019755) | HK inno.N Corporation | 2021-08-13 |
| A Study to Investigate the Safety, Tolerability, of APG-2575 as a Single Agent or in Combination for Breast Cancer (NCT04946864) | Ascentage Pharma Group Inc. | 2021-08-13 |
| A Study of [¹⁴C]-LY3484356 in Healthy Female Participants (NCT04991766) | Eli Lilly and Company | 2021-08-13 |
| Study of GDX012 in Patients With MRD Positive AML (NCT05001451) | GammaDelta Therapeutics Limited | 2021-08-13 |
| Study of ADXS-504 Immunotherapy for Recurrent Prostate Cancer (NCT05077098) | Mark Stein | 2021-08-12 |
| A Study of Ruxolitinib and Duvelisib in People With Lymphoma (NCT05010005) | Memorial Sloan Kettering Cancer Center | 2021-08-12 |
| A Pharmacokinetic and Pharmacodynamic Study of DZ-002 in Patients With Advanced Solid Malignancies or Lymphoma (NCT04970992) | Da Zen Theranostics Inc | 2021-08-12 |
| Partial Brain RT, Temozolomide, Chloroquine, and TTF Therapy for the Treatment of Newly Diagnosed Glioblastoma (NCT04397679) | Barbara Ann Karmanos Cancer Institute | 2021-08-12 |
| Single Ascending Dose Study of NH102 in Healthy Subjects (NCT05015192) | Jiangsu Nhwa Pharmaceutical Co., Ltd. | 2021-08-12 |
| Phase I/II Trial of Pembrolizumab and Androgen-receptor Inhibitor With or Without 225Ac-J591 for Progressive Metastatic Castration Resistant Prostate Cancer (NCT04946370) | Weill Medical College of Cornell University | 2021-08-12 |
| Study to Evaluate Safety and Tolerability of Iberdomide (CC-220) in Participants With Kidney Impairment Compared to Participants With Normal Kidney Function (NCT04933747) | Celgene | 2021-08-12 |
| Evaluate TCRT-ESO-A2 Autologous T Cells Expressing TCR Specific for NY-ESO-1 in Subjects With Advanced Solid Tumors (NCT04878484) | Athenex, Inc. | 2021-08-11 |
| A Study of the ADME of [14C]RIST4721 in Healthy Male Subjects (NCT05023811) | Aristea Therapeutics, Inc. | 2021-08-11 |
| A Study of BR101 Injection Alone in Subjects With Advanced Solid Tumors (NCT06001580) | BioRay Pharmaceutical Co., Ltd. | 2021-08-11 |
| Role of the Serotonin 5-HT2A Receptor in Mescaline-induced Altered States of Consciousness (NCT04849013) | University Hospital, Basel, Switzerland | 2021-08-11 |
| Phase 1b Study in Patients With Short-Lasting Unilateral Neuralgiform Headache Attacks (SUNHA) (NCT04905121) | Beckley Psytech Limited | 2021-08-11 |
| A Study of PRT1419 in Patients With Advanced Solid Tumors (NCT04837677) | Prelude Therapeutics | 2021-08-11 |
| Advanced Mesenchymal Enhanced Cell THerapY for SepTic Patients (NCT04961658) | Northern Therapeutics | 2021-08-11 |
| A Study to Investigate the Safety, Tolerability, and Processing by the Body of Intravenous and Subcutaneous RO7121932 Administration in Participants With Multiple Sclerosis (NCT05704361) | Hoffmann-La Roche | 2021-08-11 |
| Pharmacokinetic Assessment of Standard Half-Life (SHL) FVIII, Extended Half-Life (EHL) FVIII, and Efanesoctocog Alfa (BIVV001) in Severe Hemophilia A (NCT05042440) | Sanofi | 2021-08-11 |
| A Study to Learn How Safe Elinzanetant is, How it Affects the Body, and How it Moves Into, Through and Out of the Body After Single and Multiple Doses in Japanese Healthy Female Adults (NCT04981431) | Bayer | 2021-08-11 |
| A Study to Determine the Safety, Pharmacokinetics, and Pharmacodynamics of DNL343 in Participants With Amyotrophic Lateral Sclerosis (NCT05006352) | Denali Therapeutics Inc. | 2021-08-11 |
| A Study of Mitoxantrone Hydrochloride Liposome Injection in Subjects With Advanced Bone and Soft Tissue Sarcoma (NCT04900766) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2021-08-11 |
| MAX-10181 in Patients With Advanced Solid Tumor (NCT05196360) | Maxinovel Pty., Ltd. | 2021-08-11 |
| A Phase 1 Study of HEC88473 Injection in Healthy Subjects, Obese Subjects and T2DM Subjects (NCT05943886) | Dongguan HEC Biopharmaceutical R&D Co., Ltd. | 2021-08-11 |
| 64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE) (NCT04868604) | Clarity Pharmaceuticals Ltd | 2021-08-11 |
| A Trial of SHR - 1906 in Healthy Subjects (NCT04986540) | Guangdong Hengrui Pharmaceutical Co., Ltd | 2021-08-10 |
| The Safety and Efficacy of KDR2-2 Suspension Eye Drops in the Treatment of Corneal Neovascularization (NCT05011916) | Zhongshan Ophthalmic Center, Sun Yat-sen University | 2021-08-10 |
| Repeat Dosing of Psilocybin in Migraine Headache (NCT04218539) | Yale University | 2021-08-10 |
| Study to Evaluate the Safety, Tolerability, PK and PD of DISC-0974 in Healthy Subjects (NCT04999527) | Disc Medicine, Inc | 2021-08-10 |
| Neuromodulation in COVID-19 Patients (NCT04808284) | D'Or Institute for Research and Education | 2021-08-10 |
| Comparison of a Compound With Pilocarpine and Brimonidine to Improve Near Vision in Healthy Presbyopic Patients (NCT05001243) | Optall Vision | 2021-08-10 |
| A Study of Pembrolizumab and Radiation Therapy in People With Mesothelioma (NCT04897022) | Memorial Sloan Kettering Cancer Center | 2021-08-10 |
| Study With QR-504a to Evaluate Safety, Tolerability & Corneal Endothelium Molecular Biomarker(s) in Subjects With FECD3 (NCT05052554) | ProQR Therapeutics | 2021-08-10 |
| Clinical Study of the Safety and Immunogenicity of a Recombinant Viral Vector AAV5 (Adeno-Associated Virus Type 5 )-RBD (Receptor Binding Domain)-S Vaccine for the Prevention of Coronavirus Infection (COVID-19) (NCT05037188) | Biocad | 2021-08-10 |
| Intravenous T3011 Given as a Single Agent and in Combination With Other Therapy in Subjects With Advanced Solid Tumors (NCT04780217) | ImmVira Pharma Co. Ltd | 2021-08-10 |
| Corticosteroid Therapy in Pulmonary Sequelae of Covid-19 (NCT07380152) | University of Sao Paulo | 2021-08-10 |
| Safety, Tolerability and Pharmacokinetics of the New Formulation SHR-1316 in Subjects With Advanced Tumors (NCT04979390) | Jiangsu HengRui Medicine Co., Ltd. | 2021-08-10 |
| ALLEVIATE-HFrEF Study (NCT05133089) | Alleviant Medical, Inc. | 2021-08-10 |
| Phase 1 PK Study to Evaluate the PK of CIN-107 in Subjects With Hepatic Impairment (NCT05961397) | AstraZeneca | 2021-08-10 |
| 11C-YJH08 PET Imaging for Detection of Glucocorticoid Receptor Expression (NCT04927663) | Rahul Aggarwal | 2021-08-10 |
| AuriNovo for Auricular Reconstruction (NCT04399239) | 3DBio Therapeutics | 2021-08-09 |
| Positron Emission Tomography Study in Healthy Subjects to Determine the Relationship Between Plasma Concentration and Brain Target Occupancy of ASN51 (NCT06390098) | Asceneuron S.A. | 2021-08-09 |
| MDPK67b in Patients With Prostate Cancer (NCT05580107) | Med Discovery SA | 2021-08-09 |
| A Proof-of-Concept Study Evaluating EOM613 in COVID-19 Infected Patients With Severe Symptoms (NCT05212532) | EOM Pharmaceuticals | 2021-08-09 |
| Study of Efavaleukin Alfa in Healthy Chinese, Japanese, and Caucasian Participants (NCT04987333) | Amgen | 2021-08-09 |
| A Study of Fruquintinib in Combination With Tislelizumab in Advanced Solid Tumors (NCT04577963) | Hutchmed | 2021-08-09 |
| A Single and Repeated Dose Escalation of RBD1016 in Subjects with Chronic Hepatitis B Virus (HBV) Infection (NCT05017116) | Suzhou Ribo Life Science Co. Ltd. | 2021-08-09 |
| Scintigraphy Study to Evaluate the Gastrointestinal Behavior of EDP1815 Oral Dosage Forms (NCT05066373) | Evelo Biosciences, Inc. | 2021-08-09 |
| Exploratory Platform Trial to Evaluate Immunotherapy Combinations With Chemotherapy for the Treatment of Patients With Previously Untreated Metastatic Pancreatic Adenocarcinoma (NCT04787991) | Cancer Insight, LLC | 2021-08-09 |
| Study of Mesenchymal Autologous Stem Cells as Regenerative Treatment for Multiple Sclerosis (NCT04749667) | Haukeland University Hospital | 2021-08-09 |
| Inhibition of Plasma Kallikrein as a New Therapy for Lung Injury (NCT04848272) | St Vincent's Institute of Medical Research | 2021-08-09 |
| A Study of Repotrectinib in Combination With Chemotherapy in Children and Young Adults With Solid Tumor Cancer (NCT05004116) | Memorial Sloan Kettering Cancer Center | 2021-08-09 |
| A Study of BMS-986416 With and Without Nivolumab in Select Solid Tumors (NCT04943900) | Bristol-Myers Squibb | 2021-08-09 |
| SSIPP vs. PST vs. WLC (NCT04887350) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2021-08-09 |