| Anti-Covid-19 Vaccine in Children With Acute Leukemia and Their Siblings (NCT04969601) | Assistance Publique - Hôpitaux de Paris | 2021-09-29 |
| Phase 1/2 Study to Evaluate the Efficacy and Safety of Inhaled IBIO123 in Participants With Mild to Moderate COVID-19 Illness (NCT05298813) | Immune Biosolutions Inc | 2021-09-29 |
| Study of LVGN7409 (CD40 Agonist Antibody) in Locally Advanced, Metastatic or Recurrent/Refractory Malignancy (NCT05152212) | Lyvgen Biopharma Holdings Limited | 2021-09-29 |
| Carnitine Consumption and Augmentation in Pulmonary Arterial Hypertension (NCT04908397) | Vanderbilt University Medical Center | 2021-09-29 |
| A Study of Lu AG06466 in Participants With Treatment Resistant Focal Epilepsy (NCT05081518) | H. Lundbeck A/S | 2021-09-29 |
| A Study of Danavorexton in Anesthetized Adults (NCT05025397) | Takeda | 2021-09-28 |
| Intratumoral phIL12 GET (NCT05077033) | Institute of Oncology Ljubljana | 2021-09-28 |
| Safety, Tolerability, and Immunogenicity of ORI-A-ce001 for the Treatment of Acne Vulgaris (NCT05131373) | Sanofi Pasteur, a Sanofi Company | 2021-09-28 |
| A Study to Assess the Safety and Efficacy of AZD7789 in Participants With Advanced or Metastatic Solid Cancer (NCT04931654) | AstraZeneca | 2021-09-28 |
| 18F-F-AraG PET Imaging to Evaluate Immunological Response to CAR T Cell Therapy in Lymphoma (NCT05096234) | Stanford University | 2021-09-28 |
| A Study of Two Different Formulations of Pirtobrutinib (LOXO-305) In Healthy Participants (NCT06258174) | Eli Lilly and Company | 2021-09-28 |
| Investigation of Safety, Tolerability, Immunogenicity and Pharmacokinetics of Single-Dose of PF-06823859 in Japanese Healthy Participants (NCT05037409) | Pfizer | 2021-09-28 |
| ED Initiated Oral Naltrexone for AUD (NCT04817410) | Icahn School of Medicine at Mount Sinai | 2021-09-28 |
| Study of ALXN1850 in Participants With Hypophosphatasia (HPP) (NCT04980248) | Alexion Pharmaceuticals, Inc. | 2021-09-28 |
| A Study to Evaluate the Pharmacokinetics and Safety Between HCP2001 and Co-administration of Each Component in Healthy Volunteers (NCT05155995) | Hanmi Pharmaceutical Company Limited | 2021-09-28 |
| Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53) (NCT04906460) | Wave Life Sciences USA, Inc. | 2021-09-28 |
| Evaluation of the Safety, Tolerability and Efficacy of iNexin™ for the Treatment of the Signs and Symptoms Associated With Dry Eye Disease (NCT05031806) | Xequel Bio, Inc. | 2021-09-28 |
| A Study of JNJ-75229414 for Metastatic Castration-resistant Prostate Cancer Participants (NCT05022849) | Janssen Research & Development, LLC | 2021-09-28 |
| The Safety and Tolerability of STSA-1002 Following Intravenous Infusion in Healthy Subjects (NCT05032144) | Staidson (Beijing) Biopharmaceuticals Co., Ltd | 2021-09-28 |
| Panobinostat in Combination With Daratumumab, Bortezomib and Dexamethasone for the Treatment of Relapsed/Refractory Multiple Myeloma (NCT04956302) | Abdullah Khan | 2021-09-27 |
| A Study in Healthy Adults Investigating Eptinezumab Produced by 2 Different Manufacturing Cell Lines (NCT05074459) | H. Lundbeck A/S | 2021-09-27 |
| GH35 Tablets for Advanced Solid Tumors: A Study on Safety and Early Results (NCT05010694) | Suzhou Genhouse Bio Co., Ltd. | 2021-09-27 |
| A Study to Evaluate Preliminary Helicobacter Pylori Eradication After Multiple Doses of TNP-2198 Capsules Combined With Rabeprazole Sodium Enteric-coated Tablets, or Rabeprazole Sodium Enteric-coated Tablets and Amoxicillin Capsules (NCT06076681) | TenNor Therapeutics (Suzhou) Limited | 2021-09-27 |
| Safety and Preliminary Protective Efficacy of Genetically Attenuated GA2 Parasites. (NCT04577066) | Leiden University Medical Center | 2021-09-27 |
| Phase 1 Study of IPG1094 Safety, Tolerability, and PK in Healthy Participants (NCT05112159) | Nanjing Immunophage Biotech Co., Ltd | 2021-09-27 |
| A Device Study in Healthy Participants (NCT04848402) | Eli Lilly and Company | 2021-09-27 |
| High-dose Intravenous Vitamin C in Patients With Septic Shock (NCT04796636) | Melbourne Health | 2021-09-27 |
| AMG 757 and AMG 404 in Subjects With Small Cell Lung Cancer (SCLC) (NCT04885998) | Amgen | 2021-09-27 |
| A Clinical Study of 6MW3211 Injection in the Treatment of Advanced Malignant Neoplasm (NCT05048160) | Mabwell (Shanghai) Bioscience Co., Ltd. | 2021-09-27 |
| Safety, Tolerability and Efficacy of PfSPZ Vaccine Against Heterologous CHMI in US Malaria naïve Adults (NCT04966871) | Sanaria Inc. | 2021-09-27 |
| First in Human, Dose Escalation Study of AN4005 (NCT04999384) | Adlai Nortye Biopharma Co., Ltd. | 2021-09-27 |
| A Study of Lu AG06466 for the Treatment of Spasticity in Participants With Multiple Sclerosis (NCT04990219) | H. Lundbeck A/S | 2021-09-27 |
| Efficacy and Safety of IBI110 Single Agent and in Combination With Sintilimab in Patients With Relapsed or Refractory Diffuse Large B Cell Lymphoma (r/r DLBCL) (NCT05039658) | Innovent Biologics (Suzhou) Co. Ltd. | 2021-09-27 |
| Phase 1 Safety Study of Encorafenib in Chinese Patients With Advanced Metastatic BRAF V600E Mutant Solid Tumors (NCT05003622) | Pierre Fabre Medicament | 2021-09-27 |
| The Effect of Severe Kidney Impairment on Cenerimod Pharmacokinetics (NCT05004311) | Viatris Innovation GmbH | 2021-09-27 |
| Tegavivint for the Treatment of Relapsed or Refractory Leukemia (NCT04874480) | M.D. Anderson Cancer Center | 2021-09-27 |
| A Phase 1/2/3 Study of UX701 Gene Therapy in Adults With Wilson Disease (NCT04884815) | Ultragenyx Pharmaceutical Inc | 2021-09-27 |
| Safety and Pharmacokinetics Study in Healthy Japanese Volunteers (NCT05032560) | Abivax S.A. | 2021-09-27 |
| 2157GCCC:Phase 1 of Calaspargase Pegol-mknl W/ Cytarabine and Idarubicin in Newly Dx AML (NCT04953780) | West Virginia University | 2021-09-27 |
| A Study to Evaluate MK-0482 for Relapsed/Refractory Acute Myeloid Leukemia (AML) or Chronic Myelomonocytic Leukemia (CMML) (MK-0482-002) (NCT05038800) | Merck Sharp & Dohme LLC | 2021-09-26 |
| A FIH Study of YH35324 in Atopic Healthy Subjects or Subjects with Mild Allergic Diseases (NCT05061524) | Yuhan Corporation | 2021-09-26 |
| Evaluation of Safety, Tolerability & Pharmacokinetics of JYP0061 in Healthy Adults. (NCT06137911) | Guangzhou JOYO Pharma Co., Ltd | 2021-09-26 |
| A Study of ALG-020572 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single Doses in Healthy Volunteers and Multiple Doses in CHB Subjects (NCT05001022) | Aligos Therapeutics | 2021-09-25 |
| A Phase 1 Dose Escalation and Expansion Study Of SHR7280 In Subjects With Hormone Sensitive Prostate Cancer (NCT04995042) | Jiangsu HengRui Medicine Co., Ltd. | 2021-09-24 |
| Single Dose ADME Study of [14C]SJP-0008 in Healthy Male Subjects (NCT05320861) | Senju Pharmaceutical Co., Ltd. | 2021-09-24 |
| A Phase I Study of NTQ1062 in Chinese Patients With Advanced Solid Tumors (NCT06172309) | Nanjing Chia-tai Tianqing Pharmaceutical | 2021-09-24 |
| Placebo Microneedles in Healthy Volunteers (Part I) and Efficacy/Safety of Doxorubicin Microneedles in Basal Cell Cancer Subjects (Part II) (NCT04928222) | SkinJect, Inc. | 2021-09-24 |
| Positron Emission Tomography (PET) Imaging Study to Evaluate Enzyme Availability in the Central Nervous System Before and After CC-97489 Administration in Healthy Participants (NCT05065541) | Celgene | 2021-09-24 |
| Study of MCLA-129, a Human Bispecific EGFR and cMet Antibody, in Patients With Advanced NSCLC and Other Solid Tumors (NCT04930432) | Betta Pharmaceuticals Co., Ltd. | 2021-09-24 |
| TNF and Glucocorticoid Antagonist for GWI Associated Multi-symptom Disease Homeostasis Reset (NCT04254627) | Nova Southeastern University | 2021-09-24 |
| Pharmacokinetic and Mass Balance Study of Oral-Administrated [14C]-DZD9008 in Healthy Male Subjects (NCT05159895) | Dizal Pharmaceuticals | 2021-09-24 |
| A Study of Pembrolizumab and Cryoablation in People With Mesothelioma (NCT05071014) | Memorial Sloan Kettering Cancer Center | 2021-09-24 |
| Venetoclax Plus Inotuzumab for B-ALL (NCT05016947) | Dana-Farber Cancer Institute | 2021-09-24 |
| A Clinical Trial to Evaluate the Safety and Pharmacokinetics of AJU-C52L in Healthy Volunteers (NCT05077475) | AJU Pharm Co., Ltd. | 2021-09-24 |
| Teriflunomide in HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (NCT04799288) | National Institute of Neurological Disorders and Stroke (NINDS) | 2021-09-24 |
| A Clinical Study of TQB3823 in Patients With Advanced Malignant Tumor (NCT05021367) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2021-09-23 |
| Fasting Bioavailability Study of Mylan's Revefenacin Inhalation Solution (NCT05207111) | Mylan Pharma UK Ltd. | 2021-09-23 |
| Safety and Exploratory Efficacy of Transplantation Therapy Using PSA-NCAM(+) NPC in AIS-A Level of Sub-acute SCI (NCT04812431) | S.Biomedics Co., Ltd. | 2021-09-23 |
| Tregs for the Treatment of Acute Respiratory Distress Syndrome (ARDS) Associated With COVID-19 (regARDS) (NCT05027815) | Jeffrey Bluestone | 2021-09-23 |
| The Study of ONO-7913, ONO-4538 and the Standard of Care as First-line Treatment in Patients Colorectal Cancer (NCT06540261) | Ono Pharmaceutical Co., Ltd. | 2021-09-23 |
| Pharmacokinetics and Excretion of Oral [14C]-Rodatristat Ethyl (NCT05006118) | Altavant Sciences GmbH | 2021-09-23 |
| A Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SDI-118 in Elderly Male and Female Study Participants With Cognitive Decline (NCT05199142) | Syndesi Therapeutics | 2021-09-23 |
| Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction (NCT04703842) | Sardocor Corp. | 2021-09-23 |
| Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies (NCT04959175) | National Cancer Institute (NCI) | 2021-09-23 |
| Open-Label, Dose-Escalation With Expansion to Assess the Safety, Tolerability, and PK of TRE-515 in Subjects With Solid Tumors (NCT05055609) | Trethera | 2021-09-23 |
| Pharmacokinetics Study of Famitinib Malate Capsules in Healthy Subjects (NCT05046808) | Jiangsu HengRui Medicine Co., Ltd. | 2021-09-23 |
| A Study of Repotrectinib in Combination With Other Anticancer Therapies for the Treatment of Subjects With KRAS-Mutant Solid Tumors (NCT05071183) | Turning Point Therapeutics, Inc. | 2021-09-23 |
| NIR Fluorescence Molecular Imaging of ANXV-800CW in RVO Patients (NCT05133791) | University Medical Center Groningen | 2021-09-23 |
| Pivotal Bioequivalence Study to Qualify Manufacturing Site Transfer for Prazosin Hydrochloride Capsules (NCT04967443) | Pfizer | 2021-09-22 |
| Single Ascending Dose Study With 5-MeO-DMT in Healthy Subjects (NCT05032833) | Beckley Psytech Limited | 2021-09-22 |
| A Study to Evaluate Safety and Efficacy of ACT001 and Anti-PD-1 in Patients With Surgically Accessible Recurrent Glioblastoma Multiforme (NCT05053880) | Accendatech USA Inc. | 2021-09-22 |
| 68Ga-grazytracer PET/CT of Tumor Responses to Immunotherapy (NCT05000372) | Peking University Cancer Hospital & Institute | 2021-09-22 |
| A Phase 1/2 Study of CAN04 in Combination With Different Chemotherapy Regimens in Subjects With Advanced Solid Tumors (NCT05116891) | Cantargia AB | 2021-09-22 |
| Safety and Tolerability Study of SKX-16 in Subjects With Moderate to Severe Distal Subungual Onychomycosis (NCT05110638) | SATO Pharmaceutical Co., Ltd. | 2021-09-22 |
| A Study of JNJ-73763989 in Adult Participants With Renal Impairment (NCT04963738) | Janssen Research & Development, LLC | 2021-09-22 |
| Camsirubicin + Pegfilgrastim to Determine MTD in ASTS (NCT05043649) | Monopar Therapeutics | 2021-09-22 |
| A Study to Assess S011806 (DC-806 or LY4100504) in Healthy Adult Participants and Participants With Chronic Plaque Psoriasis (NCT06808815) | DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company | 2021-09-22 |
| A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma (NCT05050097) | Janssen Research & Development, LLC | 2021-09-22 |
| A Drug-Drug Interaction Study to Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Probe Substrate in Patients with Advanced GIST (NCT04530981) | Deciphera Pharmaceuticals, LLC | 2021-09-22 |
| A Phase 1 Study to Investigate the Safety and Pharmacokinetics of Fosigotifator in Patients With Amyotrophic Lateral Sclerosis (NCT04948645) | AbbVie | 2021-09-22 |
| Study of SAGE-904 Using a Ketamine Challenge to Evaluate Electrophysiology, Safety, Tolerability, and Pharmacokinetics in Healthy Participants (NCT05049343) | Supernus Pharmaceuticals, Inc. | 2021-09-21 |
| A Clinical Trial to Assess Pharmacokinetic/Pharmacodynamic Profiles and Safety of IVL3001 (NCT04945226) | Inventage Lab., Inc. | 2021-09-21 |
| Clinical Study of Recombinant Humanized CTLA-4-FC Fusion Protein Injection in Healthy Subjects (NCT05256719) | Beijing VDJBio Co., LTD. | 2021-09-21 |
| PF-07321332/Ritonavir and Ritonavir on Dabigatran Study in Healthy Participants (NCT05064800) | Pfizer | 2021-09-21 |
| A Study to Evaluate the Bioavailability of Pembrolizumab (MK-3475) Via Subcutaneous (SC) Injection of Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180) [MK-3475A] In Advanced Solid Tumors (MK-3475A-C18) (NCT05017012) | Merck Sharp & Dohme LLC | 2021-09-21 |
| Study of DCR-AUD in Healthy Volunteers (NCT05021640) | Dicerna Pharmaceuticals, Inc., a Novo Nordisk company | 2021-09-21 |
| A Study to Evaluate the Bioavailability of Fedratinib When Administered in Different Ways to Healthy Adult Participants (NCT05051553) | Bristol-Myers Squibb | 2021-09-21 |
| Treating Congestive HF With hiPSC-CMs Through Endocardial Injection (NCT04982081) | HELP Therapeutics Co., Ltd. | 2021-09-21 |
| A First Time in Human (FTIH) Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of GSK3884464 in Healthy Participants (NCT05044325) | GlaxoSmithKline | 2021-09-20 |
| The Safety and Immunogenicity Evaluation of Live Attenuated Influenza Vaccine (NCT05056519) | Changchun BCHT Biotechnology Co. | 2021-09-20 |
| PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy (NCT04837547) | University of Florida | 2021-09-20 |
| A Study of Cybis™ 10:25 THC:CBD Oil in Adults With Chronic Back/Neck Pain (NCT04976738) | Cymra Life Sciences | 2021-09-20 |
| SARS-CoV-2 CTLS for Mild to Moderate COVID-19 Disease (NCT04896606) | New York Medical College | 2021-09-20 |
| Abemaciclib in Combination With Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer (NCT05095207) | Icahn School of Medicine at Mount Sinai | 2021-09-20 |
| Phase 1b/2 Study of Futibatinib in Combination With Binimetinib in Patients With Advanced KRAS Mutant Cancer (NCT04965818) | Taiho Oncology, Inc. | 2021-09-20 |
| A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors (NCT04826341) | National Cancer Institute (NCI) | 2021-09-20 |
| APR-548 in Combination With Azacitidine for the Treatment of TP53 Myelodysplastic Syndromes (MDS) (NCT04638309) | Aprea Therapeutics | 2021-09-20 |
| A Study of ERAS-007 in Patients With Advanced Gastrointestinal Malignancies (NCT05039177) | Erasca, Inc. | 2021-09-20 |
| Study of CAR-BCMA, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against BCMA in Subjects With Multiple Myeloma (NCT05243212) | Sheba Medical Center | 2021-09-19 |
| Pharmacokinetic/Pharmacodynamic Parameters of NNG-DEPO (Stimus) With Aranesp® (Amgen) in Treatment of Anemia in CKD Patients on Dialysis (NCT05636891) | Nanogen Pharmaceutical Biotechnology Joint Stock Company | 2021-09-19 |