| A Phase I Study to Evaluate Safety, Tolerability, and Immunogenicity of a PIKA COVID-19 Vaccine in Healthy Individuals (NCT05305300) | Yisheng Biopharma (Singapore) Pte. Ltd. | 2021-10-18 |
| All-Trans Retinoic Acid (ATRA) and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer (NCT04919369) | Dwight Owen | 2021-10-18 |
| A Study to Test How Well Men Tolerate Different Doses of BI 3006337 (NCT05076422) | Boehringer Ingelheim | 2021-10-18 |
| Safety and Efficacy Active Drug vs. Placebo in Subjects With Asthma (NCT04987944) | Pfizer | 2021-10-18 |
| A Single and Multiple Ascending Dose Trial of CVL-354 in Healthy Participants (NCT05138653) | Cerevel Therapeutics, LLC | 2021-10-18 |
| Anti-BCMA Chimeric Antigen Receptor T Cells for Relapsed or Refractory Multiple Myeloma (NCT05577000) | Thomas Martin, MD | 2021-10-18 |
| A Clinical Trial of TQC3721 Suspension for Inhalation (NCT05051930) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2021-10-18 |
| To Evaluate Drug Interactions Between XNW3009, Febuxostat, and Colchicine in Patients With Gout (NCT05324423) | The Affiliated Hospital of Qingdao University | 2021-10-18 |
| Multiple Ascending Dose Study to Assess the Pharmacokinetics, Safety, and Tolerability of Orally Administered SYN 020 (NCT05045833) | Theriva Biologics, Inc. | 2021-10-18 |
| Glossopharyngeal Nerve Block on Post Tonsillectomy Pain Among Egyptian Children (NCT05109416) | Minia University | 2021-10-17 |
| A Study of Mavorixafor in Participants With Congenital Neutropenia and Chronic Idiopathic Neutropenia Disorders (NCT04154488) | X4 Pharmaceuticals | 2021-10-16 |
| A Randomized, Double-blinded, Active Controlled Crossover Clinical Trial to Investigate PK, PD and Safety of GBPD002 (NCT05585658) | Globe Biotech Limited | 2021-10-16 |
| Absorption, Metabolism, and Excretion Study of [14C]-TNP-2092 (NCT05074134) | TenNor Therapeutics Limited | 2021-10-16 |
| Dedicated Drug-Drug Interaction (DDI) Study in Healthy Volunteers (NCT04939467) | Blade Therapeutics | 2021-10-15 |
| A Study of ES102 (OX40 Agonist) in Combination With JS001 in Patients With Advanced Solid Tumors (NCT04991506) | Elpiscience Biopharma, Ltd. | 2021-10-15 |
| A Study to Compare PK, PD and Safety of the AD-213-A and AD-2131 (NCT04690868) | Addpharma Inc. | 2021-10-15 |
| NAC Treatment and Outcomes in Patients With Advanced Atherosclerosis and DM (NCT05908513) | University of Missouri-Columbia | 2021-10-15 |
| A Trial of ChAdOx1 and MVA Vaccines Against MAGE-A3 and NY-ESO-1 (NCT04908111) | Cancer Research UK | 2021-10-15 |
| CMV-TCR-T Cells for CMV Infection After Allogenic HSCT (NCT05140187) | Chinese PLA General Hospital | 2021-10-15 |
| Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TNM002 in Chinese Healthy Adults (NCT05842798) | Zhuhai Trinomab Pharmaceutical Co., Ltd. | 2021-10-15 |
| Tolerability, Pharmacokinetics and Pharmacodynamics of Ascending Single and Repeated Doses of SAR444336 in Healthy Adult Participants (NCT05876767) | Sanofi | 2021-10-15 |
| FT538 in Combination With Monoclonal Antibodies in Advanced Solid Tumors (NCT05069935) | Fate Therapeutics | 2021-10-15 |
| A Phase 1 Study of ANJ900 Chinese Healthy Subjects (NCT05151146) | Anji Pharma | 2021-10-15 |
| S095029 as Monotherapy and in Combination With Sym021 in Patients With Advanced Solid Tumor Malignancies Followed by an Expansion Part With Triple Combinations in Patients With Metastatic Gastric or Colorectal Cancers (NCT05162755) | Institut de Recherches Internationales Servier | 2021-10-15 |
| A Study to Assess the Effect of Capivasertib on Midazolam in Patients With Advanced Solid Tumours (NCT04958226) | AstraZeneca | 2021-10-15 |
| Clinical Trial on Sequential Immunization of Recombinant COVID-19 Vaccine (CHO Cells,NVSI-06-08) and Inactivated COVID-19 Vaccine (Vero Cells) in Population Aged 18 Years and Above (NCT05069129) | National Vaccine and Serum Institute, China | 2021-10-14 |
| A Phase I, Open-Label, Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Aclidinium Bromide in Healthy Chinese Participants (NCT03276052) | AstraZeneca | 2021-10-14 |
| Comparing Efficacy and Safety of TJO-083 in Dry Eye Disease Patients (NCT05346783) | Taejoon Pharmaceutical Co., Ltd. | 2021-10-14 |
| A Safety, Tolerability and Preliminary Efficacy Study of CC-90011 in Combination With Venetoclax and Azacitidine in R/R Acute Myeloid Leukemia and Treatment-naïve Participants Not Eligible for Intensive Therapy (NCT04748848) | Celgene | 2021-10-14 |
| Adipose-derived Stromal Vascular Fraction Cells to Treat Parkinson (NCT05699161) | Samuel Vilchez, PhD | 2021-10-14 |
| Safety, Tolerability and Immunogenicity of Recombinant COVID-19 Vaccine Betuvax-CoV-2 (NCT05270954) | Artgen Biotech | 2021-10-14 |
| Bioavailability Study Comparing 2 Vamifeport Oral Formulations in Fasted Versus Fed State in Healthy Subjects (NCT05077436) | Vifor (International) Inc. | 2021-10-14 |
| A Study of Safety and Immune Response to Different Doses of a Cytomegalovirus Vaccine in Healthy Adults (NCT05089630) | GlaxoSmithKline | 2021-10-14 |
| A Study of Soticlestat With Itraconazole and Mefenamic Acid in Healthy Adults (NCT05064449) | Takeda | 2021-10-14 |
| A Study to Learn How Elinzanetant Moves Into, Through, and Out of the Body, How Safe it is, and How it Affects the Body in Participants With Kidneys That do Not Work as Well as They Should Compared to Participants Whose Kidneys Work Normally (NCT05071729) | Bayer | 2021-10-14 |
| Recombinant Human Serum Albumin in Patients With Liver Cirrhosis and Ascites Subjects (NCT05249374) | Protgen Ltd | 2021-10-14 |
| A First in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of PMG1015 (NCT05022771) | Pulmongene Ltd. | 2021-10-14 |
| Phase I Trial of Atezolizumab and Interleukin-12 Gene Therapy in Metastatic Non-Small Cell Lung Cancer With Progression on First-Line Immunotherapy With or Without Chemotherapy (NCT04911166) | The Methodist Hospital Research Institute | 2021-10-14 |
| A Study of MK-6194 (PT101) in Participants With Active Ulcerative Colitis (UC) (MK-6194-002) (NCT04924114) | Merck Sharp & Dohme LLC | 2021-10-14 |
| A Study of Implantation of Retinal Pigment Epithelium in Subjects with Acute Wet Age Related Macular Degeneration (NCT01691261) | Moorfields Eye Hospital NHS Foundation Trust | 2021-10-14 |
| the Accuracy and Safety of Coronary Artery Contrast-enhanced Magnetic Resonance Imaging With Polysaccharide Superparamagnetic Iron Oxide Nanoparticle (NCT05032937) | The First Affiliated Hospital with Nanjing Medical University | 2021-10-13 |
| ALX148, Rituximab and Lenalidomide for the Treatment of Indolent and Aggressive B-cell Non-Hodgkin Lymphoma (NCT05025800) | M.D. Anderson Cancer Center | 2021-10-13 |
| Phase 1 ALKS 1140 in Healthy Adults (NCT05019105) | Alkermes, Inc. | 2021-10-13 |
| A Single-center, Randomized, Double-blinded, Placebo-controlled, Phase 1 Clinical Trial to Evaluate the Safety, Tolerability and Efficacy of NCP112 (NCT05638165) | NovaCell Technology Inc. | 2021-10-13 |
| TD-0903 Pharmacokinetics Study in Healthy Participants With Supplemental Oxygenation (NCT05091723) | Theravance Biopharma | 2021-10-13 |
| Safety, Pharmacokinetics and Efficacy of FMX114 Versus Vehicle in Adults With Atopic Dermatitis (NCT04927572) | Vyne Therapeutics Inc. | 2021-10-13 |
| Cell Therapy for Chronic Traumatic Cervical Incomplete Spinal Cord Injury (NCT05054803) | Banc de Sang i Teixits | 2021-10-13 |
| A Study of Belzutifan (MK-6482) as Monotherapy and in Combination With Lenvatinib (E7080/MK-7902) With or Without Pembrolizumab (MK-3475) in China Participants With Advanced Renal Cell Carcinoma (MK-6482-010) (NCT05030506) | Merck Sharp & Dohme LLC | 2021-10-13 |
| Stem Cell and Conditioned Medium for Cerebral Palsy (NCT04314687) | PT. Prodia Stem Cell Indonesia | 2021-10-13 |
| A Study to Assess the Effect of Food on HR20033 and Pharmacokinetic After Multiple Dose in Healthy Volunteers (NCT05120219) | Shandong Suncadia Medicine Co., Ltd. | 2021-10-13 |
| Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Advanced Solid Tumors Receiving Intravenous (IV) ABBV-400 as Monotherapy and in Combination With IV Bevacizumab (NCT05029882) | AbbVie | 2021-10-13 |
| Bioequivalence Study in Healthy Chinese Subjects Comparing SP-01 (Granisetron Patch) Manufactured at Two Different Sites (NCT05075876) | Solasia Pharma K.K. | 2021-10-13 |
| A Study in Healthy Adult Male Participants to Learn the Way Vericiguat is Absorbed With and Without Food When Taken as a Single Dose in Liquid Form Suitable for Children Compared to a 10 Milligram (mg) Tablet That Releases the Active Substance Immediately (NCT05086952) | Bayer | 2021-10-12 |
| Safety and Tolerability of Single and Multiple Doses of Neumifil (NCT05093530) | Pneumagen Ltd. | 2021-10-12 |
| Intrathecal Application of PD1 Antibody in Metastatic Solid Tumors With Leptomeningeal Disease (IT-PD1/ NOA 26) (NCT05112549) | University Hospital Tuebingen | 2021-10-12 |
| Hypoxia Imaging for Esophageal Cancer to Guide Personalized Radiation Therapy (NCT04846309) | University of Utah | 2021-10-12 |
| A Phase 1, Open-label Study of the Absorption, Metabolism, Excretion of [14C]-Resminostat (NCT04955340) | 4SC AG | 2021-10-12 |
| A Study of JMT601 in Participants With Relapsed or Refractory CD20-positive B-cell Non-Hodgkin Lymphoma (NCT06725524) | Shanghai JMT-Bio Inc. | 2021-10-12 |
| A Study to Evaluate the Pharmacokinetics (How it Moves Into, Through and Out From the Body) of a New Gadolinium-based Contrast Agent (GBCA) After Injection and How Safe it is in Participants With Normal and Impaired Renal Function (NCT05061979) | Bayer | 2021-10-12 |
| A Phase I-II Study of Novel Oncolytic Virus VG161 Via Intravesical Instillation for BCG-Unresponsive Non-Muscle-Invasive Bladder Cancer (NCT07505615) | Ding-Wei Ye | 2021-10-12 |
| A Safety and Efficacy Study of STSP-0601 in Adult Patients With Hemophilia A or B With Inhibitor (NCT05027230) | Staidson (Beijing) Biopharmaceuticals Co., Ltd | 2021-10-12 |
| Capecitabine In Combination With Cemiplimab In Patient With Metastatic Breast Cancer (NCT05064085) | H. Lee Moffitt Cancer Center and Research Institute | 2021-10-12 |
| A Trial of SHR-1703 in Asthma (NCT05042401) | Jiangsu HengRui Medicine Co., Ltd. | 2021-10-12 |
| A Study of TAK-881 in Healthy Adults (NCT05059977) | Takeda | 2021-10-12 |
| Oral CDX-7108 in Healthy Adults and EPI Subjects (NCT05082051) | Société des Produits Nestlé (SPN) | 2021-10-11 |
| First-in-human Safety and Tolerability of MP0317 in Patients With Relapsed/Refractory Advanced Solid Tumors (NCT05098405) | Molecular Partners AG | 2021-10-11 |
| A Study Comparing Different Formulations of LY3410738 in Healthy Adult Participants (NCT06181084) | Eli Lilly and Company | 2021-10-11 |
| A Study to Test if SAR443809 is Tolerated and Safe When Taken as a Single Dose in Healthy Adults (NCT06326814) | Sanofi | 2021-10-11 |
| To Evaluate the Safety, Tolerability and Pharmacokinetics of CT-P63 in Healthy Subjects (NCT05017168) | Celltrion | 2021-10-11 |
| Dendritic Cell Vaccination With Standard Postoperative Chemoradiation for the Treatment of Adult Glioblastoma (NCT04552886) | The Cooper Health System | 2021-10-11 |
| Pelareorep and Paclitaxel Injection in Chinese Patients With Advanced or Metastatic Breast Cancer (NCT05519059) | Adlai Nortye Biopharma Co., Ltd. | 2021-10-11 |
| A Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of HLX26 Monoclonal Antibody Injection in Patients With Solid Tumor or Lymphoma (NCT05078593) | Shanghai Henlius Biotech | 2021-10-11 |
| Evaluation Freethiadine Tolerance in Healthy Subjects and Patients With Chronic Hepatitis B, Pharmacokinetics Characteristics and Antiviral Activity of Ⅰ Phase of Study (NCT05391360) | Sunshine Lake Pharma Co., Ltd. | 2021-10-11 |
| Study to Evaluate the Pharmacokinetics (Movement of Drugs Within the Body), Safety and Tolerability of Brazikumab in Healthy Chinese and White Participants (NCT05033431) | AstraZeneca | 2021-10-11 |
| Pirfenidone Combined With Methylprednisolone Versus Methylprednisolone in the Treatment of CIP (NCT05280873) | Zhou Chengzhi | 2021-10-10 |
| A Study to Determine Safety and Immunogenicity of the Candidate COVID-19 Vaccine AZD1222 Delivered by Aerosol in Healthy Adult Volunteers (NCT05007275) | Imperial College London | 2021-10-10 |
| StrataGraft Overlay of Meshed Autograft in Full-thickness Thermal Burns (NCT04765202) | Stratatech, a Mallinckrodt Company | 2021-10-10 |
| A Dose-escalating Pilot Study of Orelabrutinib for Newly-diagnosed PCNSL (NCT05036577) | Huashan Hospital | 2021-10-10 |
| Study to Evaluate Tolerability of Iberdomide (CC-220) in Combination With Polatuzumab Vedotin Plus Rituximab or Tafasitamab or Rituximab Plus Chemotherapy in B-cell Lymphoma (NCT04882163) | Celgene | 2021-10-10 |
| Safety, Tolerability and Efficacy of Vaginal Suppositories for Treatment of the Endometriosis (NCT03481842) | BioGene Pharmaceutical Ltd. | 2021-10-10 |
| A Study of Bioavailability and Food Effect of SACT-1 and Edurant® Tablets in Healthy Adult Volunteers (NCT05358756) | Aptorum International Limited | 2021-10-09 |
| A Study of Absorption-Distribution-Metabolism-Excretion (ADME) of [14C]IMP4297 to China Healthy Male Subjects (NCT05109832) | Impact Therapeutics, Inc. | 2021-10-09 |
| A Study to Evaluate the Safety and Tolerability of AZD7442 in Healthy Chinese Adults (NCT05437289) | AstraZeneca | 2021-10-09 |
| Absorption, Elimination and Safety of 14C-labeled Radioactive BTZ-043, a New Compound in TB Treatment (NCT04874948) | Michael Hoelscher | 2021-10-08 |
| Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of TB006 in Participants With Alzheimer's Disease (NCT05074498) | TrueBinding, Inc. | 2021-10-08 |
| Characterizing the Pharmacokinetic Profile of a Novel Encapsulated Caffeine Beverage and Associated Mood and Physiological Effects (NCT05096780) | PepsiCo Global R&D | 2021-10-08 |
| Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease? (NCT05094271) | University of California, San Diego | 2021-10-08 |
| A Dose-escalation Study of LUNA18 in Patients With Locally Advanced or Metastatic Solid Tumors (With Expansion). (NCT05012618) | Chugai Pharmaceutical | 2021-10-08 |
| Bioavailability of Oseltamivir Phosphate 75 mg With Regards to Reference Product (NCT05083325) | Laboratorios Andromaco S.A. | 2021-10-08 |
| A Clinical Study Comparing the Pharmacokinetics and Pharmacodynamic Characteristics of Insulin Degludec Injection (RD15003) and Insulin Degludec Injection (Tresiba®) in Healthy Subjects (NCT05576298) | Sunshine Lake Pharma Co., Ltd. | 2021-10-08 |
| Nanatinostat Plus Valganciclovir in Advanced EBV+ Solid Tumors and in Combination With Pembrolizumab in EBV+ RM-NPC (NCT05166577) | Viracta Therapeutics, Inc. | 2021-10-08 |
| Safety of Ascending Single and Multiple Doses of Nebulised SoftOx Inhalation Solution in Healthy Subjects (NCT05188638) | SoftOx Solutions AS | 2021-10-08 |
| Pharmacokinetics and Safety of BV100 Administered as Single Intravenous Infusion to Subjects With Renal Impairment (NCT05086107) | BioVersys AG | 2021-10-08 |
| Clinical Trial to Investigate the Safety, Tolerability and Pharmacokinetics of BV100 in Healthy Male Subjects (NCT05087069) | BioVersys SAS | 2021-10-08 |
| A Study To Estimate The Effect of PF-06650833 On The Pharmacokinetics (PK) of Oral Contraceptive (OC) (NCT05064332) | Pfizer | 2021-10-08 |
| Treating Heart Failure With hPSC-CMs (NCT03763136) | HELP Therapeutics Co., Ltd. | 2021-10-08 |
| A Study to Evaluate Relative Bioavailability and Food-Effect of HA121-28 Tablet B in Healthy Subjects (NCT05072535) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2021-10-08 |
| AAV8-hCocH for Cocaine Use Disorder (NCT04884594) | W. Michael Hooten | 2021-10-08 |
| Itacitinib for the Treatment of Bronchiolitis Obliterans Syndrome After Donor Hematopoietic Cell Transplant (NCT04239989) | M.D. Anderson Cancer Center | 2021-10-08 |
| Safety and Efficacy of AMT-130 in European Adults With Early Manifest Huntington's Disease (NCT05243017) | UniQure Biopharma B.V. | 2021-10-07 |