| Study of Comparative Bioavailability and Pharmacokinetics of ACM-001.1) and Pindolol in Healthy Volunteers (HV) (NCT06028321) | Actimed Therapeutics Ltd | 2021-11-26 |
| Study of LM-302 in Patients With Advance Solid Tumors (NCT05161390) | LaNova Medicines Zhejiang Co., Ltd. | 2021-11-26 |
| Clinical Trial to Assess the Safety and Efficacy of Investigational Product in Patients Due to Hypospadias Treatment Failure (NCT05093166) | Holostem s.r.l. | 2021-11-26 |
| A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of HR011408 at Two Formulations in Healthy Subject (NCT05147259) | Jiangsu HengRui Medicine Co., Ltd. | 2021-11-26 |
| Study to Evaluate the Pharmacokinetic Profiles and Safety of CKD-393 (NCT05113693) | Chong Kun Dang Pharmaceutical | 2021-11-25 |
| Single and Multiple Dose Study of VER-01 in Healthy Volunteers (NCT04930809) | Vertanical GmbH | 2021-11-25 |
| Phase 1 Clinical Trial to Evaluate the Safety and Immunogenicity of HIV-1 Chimp Adenovirus Vaccines Expressing Clade C gp140 & CH505TF gp120 Protein Boost in HIV-uninfected Adult. (NCT05182125) | HIV Vaccine Trials Network | 2021-11-25 |
| Study to Assess the Safety, Tolerability, and Pharmacokinetics (Movement of Drugs Within the Body) of AZD2693 in Healthy Participants (NCT05107336) | AstraZeneca | 2021-11-25 |
| Descartes-25 in Relapsed/Refractory Multiple Myeloma (NCT05113342) | Cartesian Therapeutics | 2021-11-25 |
| Phase 1 Clinical Trial of DA-5207 in Healthy Adults (NCT05127746) | Dong-A ST Co., Ltd. | 2021-11-25 |
| Study of CDK4/6 Inhibitor Combined With PD-L1 Monoclonal Antibody in the Treatment of PD-1/PD-L1 Resistance and Abnormal Cell Cycle Digestive System Tumors (NCT05139082) | Peking University | 2021-11-24 |
| Active Myeloid Target Compound Combinations in MDS/MPN Overlap Syndromes Overlap Syndromes (ABNL-MARRO) (NCT04061421) | Michael Savona | 2021-11-24 |
| Study of the Safety and Efficacy of STI-6643 in Subjects With Advanced Solid Tumors (NCT04900519) | Sorrento Therapeutics, Inc. | 2021-11-24 |
| A Study to Evaluate Drug-Drug Interaction of Larotinib With Itraconazole and Rifampin in Healthy Adult Participants (NCT05057949) | Sunshine Lake Pharma Co., Ltd. | 2021-11-24 |
| A Phase 1 Study of PTX-35 in Healthy Volunteers (NCT05116969) | Heat Biologics | 2021-11-24 |
| A Study of Two Formulations (Both Refrigerated and Room Temperature) Using an Autoinjector Device in Healthy Participants (NCT05154968) | Eli Lilly and Company | 2021-11-24 |
| Clinical Trial to Evaluate Safety of Allogeneic Bone Marrow Derived Mesenchymal Stem Cell in Chronic Kidney Disease (NCT05042206) | Pharmicell Co., Ltd. | 2021-11-24 |
| A Study to Find the Best Dose of BI 905711 in Combination With Chemotherapy and to Test Whether This Dose Helps People With Advanced Gastrointestinal Cancers (NCT05087992) | Boehringer Ingelheim | 2021-11-24 |
| A Safety and Efficacy Study of FCR001 in Adults With Rapidly Progressive Diffuse Cutaneous Systemic Sclerosis (NCT05098145) | Talaris Therapeutics Inc. | 2021-11-24 |
| A Multiple Dose Study to Evaluate Safety, Tolerability, PK, and Efficacy of SER-155 in Adults Undergoing HSCT (NCT04995653) | Seres Therapeutics, Inc. | 2021-11-24 |
| Vorbipiprant (CR6086) / Balstilimab (AGEN2034) Combination in Stage IV Refractory pMMR - MSS CRC, and Other Metastatic GI Cancers (NCT05205330) | Rottapharm Biotech | 2021-11-23 |
| ANTIVIRAL TREATMENT OF CYTOMEGALOVIRUS IN DEPRESSION (NCT04724447) | Laureate Institute for Brain Research, Inc. | 2021-11-23 |
| Phase I Study of SHR-2002 + SHR-1316 in Patients With Advanced Malignant Tumors (NCT05082545) | Atridia Pty Ltd. | 2021-11-23 |
| Study of Efficacy and Safety of Investigational Treatment in Patients With Hidradenitis Suppurativa (NCT04989517) | Azora Therapeutics Australia Pty Ltd | 2021-11-23 |
| Study to Evaluate the Effects of AZD3427 in Patients With Heart Failure (NCT04890548) | AstraZeneca | 2021-11-23 |
| A Study to Evaluate Safety and Pharmacokinetics of BIIB104 in Healthy Japanese and Non-Japanese Participants (NCT05148481) | Biogen | 2021-11-23 |
| A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant in Patients With Presumed Nonalcoholic Steatohepatitis (NASH) (NCT05117489) | Corcept Therapeutics | 2021-11-23 |
| Multicohort Trial of Different Schemes of PM14 in Monotherapy and in Combination with Radiotherapy in Soft Tissue Sarcomas and Other Solid Tumor (NCT05146440) | Grupo Espanol de Investigacion en Sarcomas | 2021-11-23 |
| Linerixibat and Obeticholic Acid Drug Interaction Study in Healthy Adult Participants (NCT05133830) | GlaxoSmithKline | 2021-11-23 |
| Catumaxomab in Patients With Non-Muscle-Invasive Bladder Cancer Who Have Failed or Are Intolerant to BCG Vaccine (NCT04799847) | LintonPharm Co.,Ltd. | 2021-11-23 |
| Study to Assess the Pharmacokinetics of Pelacarsen (TQJ230) in Participants With Mild Hepatic Impairment Compared to Matched Healthy Participants (NCT05026996) | Novartis Pharmaceuticals | 2021-11-23 |
| Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV (NCT04514484) | National Cancer Institute (NCI) | 2021-11-22 |
| A Clinical Trial of HEC93077 in Chinese Healthy Subjects and HUA Patients With Single or Multiple Dosing (NCT05127772) | Sunshine Lake Pharma Co., Ltd. | 2021-11-22 |
| Study of Pembrolizumab Treatment After CYAD-101 With FOLFOX Preconditioning in Metastatic Colorectal Cancer (NCT04991948) | Celyad Oncology SA | 2021-11-22 |
| In Vivo Proof-of-principle Study of Raman Spectroscopy in Trial Participants With Bladder Tumours (NCT05124106) | University Hospital Bispebjerg and Frederiksberg | 2021-11-22 |
| Pharmacokinetics of Cobitolimod Enemas in Participants With Active Ulcerative Colitis (NCT05404074) | InDex Pharmaceuticals | 2021-11-22 |
| A Clinical Pharmacology Trial of Brexpiprazole Long Acting Injectable (LAI) Administered as a Single Dose in Patients With Schizophrenia (NCT05119894) | Otsuka Pharmaceutical Co., Ltd. | 2021-11-22 |
| Study of Intravaginal Tamoxifen in PostMenopausal Women With VVA (NCT05378269) | Daré Bioscience, Inc. | 2021-11-22 |
| A Study of Soticlestat and Rifampin in Healthy Adults (NCT05098041) | Takeda | 2021-11-22 |
| Evaluation of Safety, Tolerability, and Efficacy of INZ-701 in Adults With ENPP1 Deficiency (NCT04686175) | Inozyme Pharma | 2021-11-21 |
| Targeted Alpha Therapy Using Astatine (At-211) Against Differentiated Thyroid Cancer (NCT05275946) | Osaka University | 2021-11-20 |
| ADME Study of [14C]- Larotinib in Healthy Male Subjects (NCT05059743) | Sunshine Lake Pharma Co., Ltd. | 2021-11-20 |
| Study to Assess AFM24 in Combination With Atezolizumab in Selected Advanced/Metastatic EGFR-expressing Cancers (NCT05109442) | Affimed GmbH | 2021-11-19 |
| A Study of LP-128 Capsules in Healthy Subjects (NCT05130567) | Guangzhou Lupeng Pharmaceutical Company LTD. | 2021-11-19 |
| Study to Assess Safety, Reactogenicity and Immunogenicity of the repRNA(QTP104) Vaccine Against SARS-CoV-2(COVID-19) (NCT05876364) | Quratis Inc. | 2021-11-19 |
| Evaluation of the Pharmacokinetics, Safety and Tolerability of Single Dose of PF-06480605 in Chinese Healthy Participants (NCT05107492) | Pfizer | 2021-11-19 |
| A Study of Multiparametric MRI and pHLIP® ICG in Breast Cancer Imaging During Surgery (NCT05130801) | Memorial Sloan Kettering Cancer Center | 2021-11-19 |
| Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Itraconazole (NCT05084651) | Novartis Pharmaceuticals | 2021-11-18 |
| Assess the Safety, Tolerability and Pharmacokinetics of AZD5055 Following Single and Multiple Ascending Doses in Healthy Participants (NCT05134727) | AstraZeneca | 2021-11-18 |
| CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) (NCT05143996) | Cullinan Therapeutics Inc. | 2021-11-18 |
| Phase 1 Study to Determine the Metabolism and Clearance of Baxdrostat (NCT05961384) | AstraZeneca | 2021-11-18 |
| Head-to-head Comparison of Diagnosis Value of Pulmonary Fibrosis on 68Ga-FAPI-04 and 18F-FDG PET-CT (NCT05121779) | Peking Union Medical College Hospital | 2021-11-18 |
| A Study to Evaluate Safety & Immunogenicity of SARS-CoV-2 DNA Vaccine Delivered Intramuscularly Followed by Electroporation for COVID-19 (NCT05102643) | The University of Hong Kong | 2021-11-18 |
| Duvelisib in Combination With BMS-986345 in Lymphoid Malignancy (NCT05065866) | H. Lee Moffitt Cancer Center and Research Institute | 2021-11-18 |
| Evaluation of IBI302 Injection in nAMD or DME (NCT05961007) | Innovent Biologics (Suzhou) Co. Ltd. | 2021-11-18 |
| Pharmacokinetics and Pharmacodynamics Clinical Study of VC005 Tablets in Healthy Subjects (NCT05138770) | Jiangsu vcare pharmaceutical technology co., LTD | 2021-11-18 |
| Clinical Effect, Safety and Tolerability of GSK1070806 in Atopic Dermatitis (NCT04975438) | GlaxoSmithKline | 2021-11-18 |
| Nasal Protollin in Early Symptomatic Alzheimer's Disease (NCT07187141) | Brigham and Women's Hospital | 2021-11-18 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of TAK-988 in Healthy Participants (NCT04082481) | Takeda | 2021-11-17 |
| First in Human Study of TORL-1-23 in Participants With Advanced Cancer (NCT05103683) | TORL Biotherapeutics, LLC | 2021-11-17 |
| Immune Response to PNEUMOVAX 23 in Healthy Adults Receiving Efgartigimod IV (NCT05163834) | argenx | 2021-11-17 |
| A Study With TEPEZZA in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc) (NCT04478994) | Amgen | 2021-11-17 |
| A Study to Assess the Effect of Food on the Absorption and Bioavailability of PBI-200 (NCT05160389) | Pyramid Biosciences | 2021-11-17 |
| Clinical Study of JS007 in Patients With Advanced Solid Tumors (NCT05049265) | Shanghai Junshi Bioscience Co., Ltd. | 2021-11-17 |
| A Study of the Safety, Tolerability, Pharmacokinetics and Food Effect After Single and Multiple Ascending Oral Doses (NCT05218434) | Artax Biopharma Inc | 2021-11-17 |
| Atoguanil BA Study (NCT04866602) | Medicines for Malaria Venture | 2021-11-17 |
| Multi Tumor-Associated Antigen-Specific T Lymphocytes to Treat Patients With High Risk Solid Tumors (NCT05238792) | Children's National Research Institute | 2021-11-17 |
| An Open-Label Study Following Oral Dosing of Seladelpar to Participants With Primary Biliary Cholangitis (PBC) and Hepatic Impairment (HI) (NCT04950764) | Gilead Sciences | 2021-11-16 |
| Safety Evaluation of KX01 Ointment 1% in Japanese Healthy Male Subjects (NCT05245578) | PharmaEssentia | 2021-11-16 |
| A Study of Enlicitide Chloride (MK-0616 Oral PCSK9 Inhibitor) in Participants With Moderate Renal Impairment (MK-0616-007) (NCT05070390) | Merck Sharp & Dohme LLC | 2021-11-16 |
| Zanubrutinib in Combination With R-PolaCHP (ZaR-PolaCHP) for Newly Diagnosed Diffuse Large B-Cell Lymphoma (NCT04850495) | Yazeed Sawalha | 2021-11-16 |
| Mass Balance and Biotransformation Study of [14C]DBPR108 in Human (NCT05072028) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2021-11-16 |
| A Study of a Rilpivirine Extended-Release Suspension in Healthy Participants (NCT05112939) | Janssen Research & Development, LLC | 2021-11-16 |
| OH2 Oncolytic Viral Therapy in Central Nervous System Tumors (NCT05235074) | Binhui Biopharmaceutical Co., Ltd. | 2021-11-16 |
| Study of Fully Human B7H3 CAR-T in Treating Recurrent Malignant Ovarian Cancer (NCT05211557) | The Affiliated Hospital of Xuzhou Medical University | 2021-11-16 |
| Study in Subjects With Rheumatoid Arthritis to Evaluate the Effect of a Single Dose of Olokizumab on the Pharmacokinetics of Substrates for CYP1A2, CYP2C9, CYP2C19 and CYP3A4 (NCT04246762) | R-Pharm International, LLC | 2021-11-16 |
| Empagliflozin as a Treatment for Severe Congenital Neutropenia Due to G6PC3 Deficiency (NCT05078879) | National Institute of Allergy and Infectious Diseases (NIAID) | 2021-11-16 |
| Safety, Tolerability, and Pharmacokinetics of RSV Monoclonal Antibody RSM01 in Healthy Adults (NCT05118386) | Gates Medical Research Institute | 2021-11-16 |
| Combination of Stereotactic Radiosurgery and Enhanced Immunotherapy for Recurrent Glioblastomas(inSituVac2)(CSREIG) (NCT05131711) | Beijing Tiantan Hospital | 2021-11-16 |
| Drug-drug Interaction Study of Rosuvastatin and AT-527 (R07496998) (NCT05154123) | Atea Pharmaceuticals, Inc. | 2021-11-16 |
| A Phase I/II Study of CM355 in Patients With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma (B-NHL) (NCT05210868) | Beijing InnoCare Pharma Tech Co., Ltd. | 2021-11-16 |
| Drug-Drug Interaction Study of IV QPX2014 Combined With QPX7728 in Healthy Adult Subjects (NCT05072444) | Qpex Biopharma, Inc. | 2021-11-15 |
| First-in-Human, Single- and Multiple-Ascending Dose and Food-Effect Study of BGB-23339 in Healthy Participants (NCT05093270) | BeiGene | 2021-11-15 |
| Safety and Efficacy of Encapsulated Allogeneic MPS-1 Therapy (NCT05665036) | Sigilon Therapeutics, Inc. | 2021-11-15 |
| Human ECM Implanted Within Microfracture Interstices & the Cartilage Defect in the Knee to Regenerate Hyaline Cartilage (NCT05082831) | Histogen | 2021-11-15 |
| Phase1/2a Study for IPG7236 in Patients With Advanced Solid Tumors (NCT05142592) | Nanjing Immunophage Biotech Co., Ltd | 2021-11-15 |
| A Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of PGDM1400LS Alone and in Combination With VRC07-523LS and PGT121.414.LS in Healthy, HIV-uninfected Adult Participants (NCT05184452) | National Institute of Allergy and Infectious Diseases (NIAID) | 2021-11-15 |
| Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia (NCT04898894) | St. Jude Children's Research Hospital | 2021-11-15 |
| PSB202 in Patients With Previously Treated-, Relapsed-, Indolent B-Cell Malignancies (NCT05003141) | Qilu Puget Sound Biotherapeutics (dba Sound Biologics) | 2021-11-15 |
| Pilot Trial on Immunosuppression Modulation to Increase SARS-CoV-2 Vaccine Response in Kidney Transplant Recipients (NCT05338177) | Medical University of Vienna | 2021-11-15 |
| Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease (NCT04819841) | Kamau Therapeutics | 2021-11-15 |
| A Study Evaluating the Bioavailability and Food Effect of Veliparib Tablets Followed by an Extension in Subjects With Ovarian Cancer (NCT03400306) | AbbVie | 2021-11-15 |
| Phase Ib/II Trial of Envafolimab Plus Lenvatinib for Subjects With Solid Tumors (NCT05024214) | 3D Medicines (Sichuan) Co., Ltd. | 2021-11-15 |
| Pharmacokinetics of Amcenestrant in Female Hepatic Impaired Participants as Compared to Participants With Normal Hepatic Function (NCT05126329) | Sanofi | 2021-11-15 |
| A Study of JNJ-75105186 in Healthy Japanese and Chinese Participants (NCT05159128) | Janssen Pharmaceutical K.K. | 2021-11-15 |
| A Clinical Trial to Evaluate the Safety and Efficacy of ADX-629 in in Subjects With Elevated Ethanol Levels (NCT05487404) | Aldeyra Therapeutics, Inc. | 2021-11-15 |
| Empagliflozin in Diuretic Refractory Ascites (NCT05013502) | Stanford University | 2021-11-15 |
| A Study of ALPN-303 in Adult Healthy Volunteers (NCT05034484) | Alpine Immune Sciences, Inc. | 2021-11-15 |
| Single Ascending Dose and Multiple Ascending Dose Study of Niclosamide Inhalation Powder in Healthy Adult Subjects (NCT05168644) | TFF Pharmaceuticals, Inc. | 2021-11-14 |
| Evaluation of Inactivated Vaccine in Healthy Adults Against Coronavirus Disease of 2019 (COVID-19) (NCT05128721) | National Research Centre, Egypt | 2021-11-14 |