| Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation (NCT05288205) | Allist Pharmaceuticals, Inc. | 2022-04-14 |
| Study of Intravenously Administered Anti-LIGHT Monoclonal Antibody CBS001 in Healthy Volunteers (NCT05323110) | Capella Bioscience Ltd | 2022-04-14 |
| Study of GSK3965193 in Healthy Participants and Participants Living With Chronic Hepatitis B Infection (NCT05330455) | GlaxoSmithKline | 2022-04-14 |
| Zofin to Treat COVID-19 Long Haulers (NCT05228899) | ZEO ScientifiX, Inc. | 2022-04-14 |
| Novel GPC3 CAR-T Cell Therapy for Hepatocellular Carcinoma (NCT05344664) | Peking University | 2022-04-14 |
| CYNK-101 in Combination with Trastuzumab and Pembrolizumab in Patients with Locally Advanced Unresectable or Metastatic HER2-Positive Gastric or Gastroesophageal Junction (G/GEJ) Adenocarcinoma (NCT05207722) | Celularity Incorporated | 2022-04-14 |
| A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors (NCT05070247) | Takeda | 2022-04-14 |
| Safety and Immunogenicity of COVI-VAC as a Booster Dose in Adults Previously Vaccinated Against COVID-19 (NCT05233826) | Codagenix, Inc | 2022-04-14 |
| IBI397 or Combination Therapies in Patients With Advanced Malignancies (NCT05245916) | Innovent Biologics (Suzhou) Co. Ltd. | 2022-04-14 |
| MSLN STAR-T Cells in the Treatment of Advanced Malignant Solid Tumors (NCT05344976) | Peking University | 2022-04-14 |
| Gas Exchange MRI to Visualize Regional Therapy Response in Interstitial Lung Disease (NCT06012500) | Children's Hospital Medical Center, Cincinnati | 2022-04-14 |
| A Study to Investigate CYC140, in Subjects With Advanced Solid Tumors and Lymphoma (NCT05358379) | Cyclacel Pharmaceuticals, Inc. | 2022-04-14 |
| A Study to Assess the Safety, Tolerability, and Pharmacokinetics of E6742 in Systemic Lupus Erythematosus Participants (NCT05278663) | Eisai Co., Ltd. | 2022-04-14 |
| A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies (NCT05131022) | Nurix Therapeutics, Inc. | 2022-04-13 |
| A Study to Investigate the Safety and Clinical Activity of Belantamab Mafodotin in Combination With Daratumumab, Lenalidomide and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Transplant Ineligible (NCT05280275) | Hellenic Society of Hematology | 2022-04-13 |
| Phase I Study of Sintilimab in Healthy Chinese Male Subjects (NCT05337267) | Innovent Biologics (Suzhou) Co. Ltd. | 2022-04-13 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of REGN9035 in Healthy Adult Volunteers and Mildly Hypertensive Participants (NCT05291546) | Regeneron Pharmaceuticals | 2022-04-13 |
| A Study of Various Respiratory Syncytial Virus (RSV) Pre-Fusion (preF)-Based Vaccine Formulations in Adults Aged 60 Years and Older (NCT05327816) | Janssen Vaccines & Prevention B.V. | 2022-04-13 |
| From Fungus to Virus, Investigating the Safety and Efficacy of Terbinafine in Chronic Hepatitis B Patients (NCT06295328) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2022-04-13 |
| Study to Compare the Pharmacokinetics, Safety and Tolerability of the Pediatric and Adult Branaplam Formulation in Healthy Adults and the Effect of Food on the Latter. (NCT05330286) | Novartis Pharmaceuticals | 2022-04-13 |
| To Access the Safety and Effects of Intravenous Administration of VIR-5818 Alone and in Combination With Pembrolizumab in Adult Participants With Locally Advanced or Metastatic HER2-Expressing Cancers (NCT05356741) | Vir Biotechnology, Inc. | 2022-04-13 |
| To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors (NCT05253053) | TransThera Sciences (Nanjing), Inc. | 2022-04-13 |
| Study of NG-350A Plus Pembrolizumab in Metastatic or Advanced Epithelial Tumours (FORTIFY) (NCT05165433) | Akamis Bio | 2022-04-13 |
| Study to Evaluate Pharmacokinetics, Pharmacodynamics, and Safety of Sargramostim Administered Subcutaneously, Intravenously, or by Inhalation (NCT05366283) | Partner Therapeutics, Inc. | 2022-04-13 |
| XW004 To Evaluate the Safety, Tolerability, PK, and PD of Oral Ecnoglutide Tablet in Healthy Adults (NCT05184322) | Sciwind Biosciences APAC CO Pty. Ltd. | 2022-04-12 |
| Safety and Tolerability, Pharmacokinetic, and Pharmacodynamic Study of ALXN1910 in Healthy Participants (NCT05307978) | Alexion Pharmaceuticals, Inc. | 2022-04-12 |
| Phase 1/2 Study of Avutometinib (VS-6766) + Sotorasib With or Without Defactinib in KRAS G12C NSCLC Patients (NCT05074810) | Verastem, Inc. | 2022-04-12 |
| A Study to Test Whether Different Combinations of BI 765063, Ezabenlimab, Chemotherapy, Cetuximab, and BI 836880 Help People With Head and Neck Cancer or Liver Cancer (NCT05249426) | Boehringer Ingelheim | 2022-04-12 |
| Safety and Tolerability of Regeneron Anti-SARS-CoV-2 Monoclonal Antibody/Ies in Adult Healthy Volunteers as Related to COVID-19 (NCT05293678) | Regeneron Pharmaceuticals | 2022-04-12 |
| The Using Postoperative Ketamine and Exploring the Effect on Endometriosis Pain (UPKEEEP) Study (NCT05229653) | NYU Langone Health | 2022-04-12 |
| Fruquintinib Plus Capecitabine as Maintenance Treatment of RAS / BRAF Wild-type Metastatic Colorectal Cancer (NCT05016869) | Chinese Academy of Medical Sciences | 2022-04-12 |
| IMCY-0141 Safety and Efficacy in Multiple Sclerosis - ISEMIS Study (NCT05417269) | Imcyse SA | 2022-04-12 |
| Ascending Multiple Intravenous Doses of AON-D21 in Healthy Male Subjects. (NCT05343819) | Aptarion Biotech AG | 2022-04-12 |
| Study of XL114 in Subjects With Non-Hodgkin's Lymphoma (NCT05144347) | Exelixis | 2022-04-12 |
| A Research Study Looking at New Protein-based Tablets in Healthy Men - Oral Formulation II (NCT05333107) | Novo Nordisk A/S | 2022-04-12 |
| An Open-label, Phase I/II Study of PLENA Regimen in Patients With Unresectable Pancreatic Cancer or BTC (NCT05327582) | Chinese PLA General Hospital | 2022-04-12 |
| Study of Single Ascending Doses of Elsulfavirine to Evaluate the Safety, Tolerability, and Pharmacokinetics of Elsulfavirine and Its Active Metabolite VM-1500A in Healthy Subjects (NCT05165550) | Viriom | 2022-04-12 |
| A Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Dosed of HSK36273 in Healthy Volunteers (NCT05742126) | Haisco Pharmaceutical Group Co., Ltd. | 2022-04-11 |
| First-in-human Single and Multiple Dose Trial of ATR-258 (NCT05409924) | Atrogi AB | 2022-04-11 |
| A Study Exploring Efficacy of Pegloticase in Subjects With Asymptomatic Hyperuricemia (NCT05302388) | Shanghai Institute Of Biological Products | 2022-04-11 |
| Safety and Immunogenicity of a Monovalent mRNA Vaccine Encoding Influenza Hemagglutinin in Adult Participants 18 Years of Age and Older (NCT06118151) | Sanofi Pasteur, a Sanofi Company | 2022-04-11 |
| 64Cu-SAR-bisPSMA for Identification of Participants With Recurrence of Prostate Cancer (COBRA) (NCT05249127) | Clarity Pharmaceuticals Ltd | 2022-04-11 |
| A Study to Investigate the Absolute Bioavailability, Absorption, Metabolism, Distribution and Excretion of [14C]AZD5363 (Capivasertib) (NCT05419401) | AstraZeneca | 2022-04-11 |
| A Safety and Pharmacokinetic Study of Complarate (Tocilizumab Biosimilar) and Actemra® in Healthy Volunteers (NCT06481202) | AO GENERIUM | 2022-04-11 |
| Study of Erdafitinib Intravesical Delivery System for Localized Bladder Cancer (NCT05316155) | Janssen Research & Development, LLC | 2022-04-11 |
| Comparison of Pharmacokinetics and Safety of HS627(2 Specifications) Versus PERJETA With a Single Injection (NCT05323981) | BioRay Pharmaceutical Co., Ltd. | 2022-04-11 |
| Study of DARE-HRT1 Over 12 Weeks in Healthy PostMenopausal Women (NCT05367973) | Daré Bioscience, Inc. | 2022-04-11 |
| Bioavailability of Eszopiclone 3.0 mg With Regards to Reference Product (NCT05349396) | Laboratorios Andromaco S.A. | 2022-04-11 |
| Evaluation of Safety, Tolerability, and Efficacy of INZ-701 in Adults With ABCC6 Deficiency Causing PXE (NCT05030831) | Inozyme Pharma | 2022-04-11 |
| A Study of ILB2109 in Patients With Advanced Solid Malignancies (NCT05278546) | Innolake Biopharm | 2022-04-11 |
| Mutant KRAS -Targeted Long Peptide Vaccine for Patients at High Risk of Developing Pancreatic Cancer (NCT05013216) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2022-04-11 |
| A Study of PM1022 in Patients With Advanced Tumors (NCT05867771) | Biotheus Inc. | 2022-04-11 |
| Pharmacogenetics of Response to GLP1R Agonists (NCT05071898) | University of Maryland, Baltimore | 2022-04-11 |
| Intramuscular CodaVax-H1N1 in Healthy Adults (NCT05223179) | Codagenix, Inc | 2022-04-11 |
| Bomedemstat and Maintenance Immunotherapy for Treatment of Newly Diagnosed Extensive Stage Small Cell Lung Cancer (NCT05191797) | University of Washington | 2022-04-11 |
| A Study to Evaluate the Safety and Efficacy of Max-40279 and Toripalimab in Patients With Advanced Solid Tumors (NCT05369286) | Maxinovel Pty., Ltd. | 2022-04-11 |
| Dose-Escalation and Dose-Expansion Study of IO-202 and IO-202+Pembrolizumab in Solid Tumors (NCT05309187) | Immune-Onc Therapeutics | 2022-04-11 |
| Corchorus Olitorius Buccal Films for the Treatment of Recurrent Minor Aphthous Ulcerations (NCT05392842) | Deraya University | 2022-04-10 |
| A Prospective Study of Ranibizumab in the Treatment of Postoperative Recurrent Vitreous Haemorrhage of Diabetic Retinopathy (NCT05248334) | Tianjin Medical University Eye Hospital | 2022-04-10 |
| A Study to Assess Relative Bioavailability of Branebrutinib, From a Tablet Formulation to the Capsule Formulation, the Effect of Food on the Bioavailability of Branebrutinib From a Tablet Formulation, and the Safety and Drug Levels of Branebrutinib From a Tablet Formulation in Healthy Participants (NCT05303220) | Bristol-Myers Squibb | 2022-04-08 |
| A Study of Orally Administered JBI-802, an LSD1/HDAC6 Inhibitor, in Patients With Advanced Solid Tumors (NCT05268666) | Jubilant Therapeutics Inc. | 2022-04-08 |
| A Study for Optimization of 6% Hydroxyethyl Starch Based Indocyanine Green Near-infrared Fluorescence Navigated Sentinel Lymph Node Biopsy for Breast Cancer Patients (NCT05365204) | National Taiwan University Hospital Hsin-Chu Branch | 2022-04-08 |
| A Pilot Study to Evaluate the PK Profile of PrimeC-ER Tablets in Healthy Adult Subjects (NCT05232461) | NeuroSense Therapeutics Ltd. | 2022-04-08 |
| To Observe the Dual-target Chimeric Antigen Receptor T Cells in the Treatment of B Cell Hematologic Tumors (NCT05388695) | Hebei Senlang Biotechnology Inc., Ltd. | 2022-04-08 |
| Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Male and Female Subjects and Safety, Tolerability, Pharmacokinetics, and Pilot Efficacy Biomarkers in Subjects With Cold Agglutinin Disease (NCT05318534) | Gliknik Inc. | 2022-04-08 |
| A Phase 1 Dose Escalation Study of Oral VX-708 in Healthy Participants (NCT05347394) | Vertex Pharmaceuticals Incorporated | 2022-04-08 |
| Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CHK-336 in Healthy Volunteers (NCT05367661) | Chinook Therapeutics, Inc. | 2022-04-08 |
| Oral Cannabidiol Effect on Blood Pressure in Hypertensive Patients (NCT05346562) | University of Split, School of Medicine | 2022-04-08 |
| Study of ASN004 in Patients With Advanced Solid Tumors (NCT04410224) | Kirilys Therapeutics Inc. | 2022-04-08 |
| A Phase I Clinical Study of SSD8432 in Healthy Adult Subjects (NCT05339646) | Jiangsu Simcere Pharmaceutical Co., Ltd. | 2022-04-07 |
| A Phase 1 Dose Escalation Study to Evaluate Safety and Pharmacokinetics (PK) of VX-840 in Healthy Participants (NCT05324410) | Vertex Pharmaceuticals Incorporated | 2022-04-07 |
| Modi-1 Moditope in Breast, Head and Neck, Ovarian, or Renal Cancer (NCT05329532) | Scancell Ltd | 2022-04-07 |
| Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer (NCT05319873) | Jonsson Comprehensive Cancer Center | 2022-04-07 |
| A Phase 1 Study Investigating the Safety, Tolerability and Pharmacokinetics of KNX100 in Healthy Volunteers (NCT04901078) | Kinoxis Therapeutics Pty Ltd | 2022-04-07 |
| Safety, Tolerability, and Pharmacokinetics of Ascending Topical Doses of TCP-25 Applied to Epidermal Suction Blister Wounds, Non-Healing Leg Ulcers and Patients With Dystrophic Epidermolysis Bullosa. (NCT05378997) | Xinnate AB | 2022-04-07 |
| A Study of Orally Administered IPG7236 in Healthy Adult Participants (NCT05288543) | Nanjing Immunophage Biotech Co., Ltd | 2022-04-07 |
| A Study of ATG-010 in Combination With Lenalidomide and Rituximab (R2) in Adults With DLBCL and iNHL (NCT05265975) | Antengene Corporation | 2022-04-07 |
| Study of ALXN2050 in Participants With Hepatic Impairment (NCT05259085) | Alexion Pharmaceuticals, Inc. | 2022-04-07 |
| Study of Efficacy and Safety of ABO809 in Healthy Participants (NCT05036668) | Novartis Pharmaceuticals | 2022-04-07 |
| A Crossover Bioequivalence Study of Olaparib Tablets, 150 mg (Lek Pharmaceuticals d.d.) and Lynparza® (Olaparib) Tablets 150 mg (AstraZeneca Pharmaceuticals LP), in Patients With Breast Cancer Gene (BRCA) Mutated Ovarian Cancer, Recurrent Ovarian Cancer or Metastatic Breast Cancer (NCT05258747) | Sandoz | 2022-04-07 |
| (VELA) Study of BLU-222 in Advanced Solid Tumors (NCT05252416) | Blueprint Medicines Corporation | 2022-04-07 |
| Personalized Feedback After Alcohol Health Education for Members of Greek Life (GREEK Study) (NCT05107284) | Abby Braitman | 2022-04-06 |
| A Study of mRNA-1020 and mRNA-1030 Seasonal Influenza Vaccines in Healthy Adults (NCT05333289) | ModernaTX, Inc. | 2022-04-06 |
| Study to Evaluate the PK of IV and PO Omadacycline in Children and Adolescents With Suspected or Confirmed Bacterial Infections (NCT05217537) | Paratek Pharmaceuticals Inc | 2022-04-06 |
| Bioavailability of SC Formulation and Japanese Ethnobridging Study for PRA023 (NCT05354349) | Prometheus Biosciences, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 2022-04-06 |
| Intravenously Administered M6229 in Critically Ill Sepsis Patients (NCT05208112) | A.P.J. Vlaar | 2022-04-05 |
| Pharmacokinetics and Safety of Cefazolin 3gm DUPLEX in Adults (NCT05205486) | B. Braun Medical Inc. | 2022-04-05 |
| T-cell Receptor α/β Depleted Donor Lymphocyte Infusion (NCT05350163) | Guenther Koehne | 2022-04-05 |
| A Study to Evaluate the Combination of YH003, YH001 and Pembrolizumab in Subjects with Advanced Solid Tumors (NCT05176509) | Eucure (Beijing) Biopharma Co., Ltd | 2022-04-05 |
| Study of ADI-PEG 20, Venetoclax and Azacitidine in Acute Myeloid Leukemia (NCT05001828) | Polaris Group | 2022-04-05 |
| Safety and Tolerability of RPE Stem Cell-derived RPE(RPESC-RPE) Transplantation in Patients With Dry Age-related Macular Degeneration (AMD) (NCT04627428) | Luxa Biotechnology, LLC | 2022-04-05 |
| A Dose Finding Study to Treat Bone Tumor(s) (NCT06008483) | QSAM Therapeutics, Inc. | 2022-04-05 |
| A Study Evaluating the Safety, Pharmacokinetic and Anti-tumor Activity of RO7428731 in Participants With Glioblastoma (NCT05187624) | Hoffmann-La Roche | 2022-04-05 |
| Safety and Immune Response of Adjuvanted SARS-CoV-2 (COVID-19) Beta Variant RBD Recombinant Protein (DoCo-Pro-RBD-1 + MF59®) and mRNA (MIPSCo-mRNA-RBD-1) Vaccines in Healthy Adults (NCT05272605) | University of Melbourne | 2022-04-05 |
| Study of TAVO103A in Healthy Volunteers (NCT05313152) | Tavotek Biotherapeutics | 2022-04-05 |
| Enhancing Prolonged Exposure With Cannabidiol to Treat Posttraumatic Stress Disorder (NCT05132699) | The University of Texas Health Science Center at San Antonio | 2022-04-04 |
| Ketamine for OUD and Comorbid Depression (OUDCD) (NCT05051449) | University of Maryland, Baltimore | 2022-04-04 |
| Assess Use of 18F-Fluciclovine for Patients With Large Brain Metastases Treated With Staged Stereotactic Radiosurgery (NCT04689048) | Baptist Health South Florida | 2022-04-04 |
| A Study to Assess the Bioequivalence Between Brivaracetam Tablet and Dry Syrup in Healthy Male Japanese Study Participants (NCT05315947) | UCB Biopharma SRL | 2022-04-04 |
| A Study to Compare the Pharmacokinetics of CSL312 Administered by Prefilled Syringe Assembled to Autoinjector to the Pharmacokinetics Administered by Prefilled Syringe Assembled to Needle Safety Device in Healthy Subjects (NCT05306275) | CSL Behring | 2022-04-04 |