| Single and Multiple Ascending Dose Study to Evaluate AMG 786 in Healthy Participants and Participants With Obesity (NCT05406115) | Amgen | 2022-07-26 |
| Pharmacokinetics and Safety/Tolerability Profile of CKD-379 (NCT05452525) | Chong Kun Dang Pharmaceutical | 2022-07-26 |
| A PET Study Following a Single Oral Dose of ITI-333 in Healthy Subjects (NCT05470101) | Intra-Cellular Therapies, Inc. | 2022-07-26 |
| A Clinical Study to Evaluate the Safety and Tolerability of JS107 in Advanced or Metastatic Solid Tumors (NCT05502393) | Shanghai Junshi Bioscience Co., Ltd. | 2022-07-26 |
| Evaluate the Safety, Tolerability, Pharmacokinetic Characteristics and Preliminary Efficacy of HLX26 and HLX10 in Patients With Advanced/Metastatic Solid Tumor (NCT05400265) | Shanghai Henlius Biotech | 2022-07-26 |
| A Multiple-Dose PK Study to Evaluate the Comparative Bioavailability of PrimeC Tablets to Ciprofloxacin Tablets Co-administered With Celecoxib Capsules, in Healthy Adult Subject (NCT05436678) | NeuroSense Therapeutics Ltd. | 2022-07-26 |
| Ortho-R® for Rotator Cuff Repair Compared With Standard of Care Rotator Cuff Repair Without Ortho-R® (NCT05333211) | ChitogenX Inc | 2022-07-26 |
| NewishT Cell Therapy for HCC With High Risk of Recurrence After Radical Resection (NCT05352646) | Newish Technology (Beijing) Co., Ltd. | 2022-07-26 |
| Study on the Body Mass Balance and Biotransformation of [14C]-HEC585 (NCT05468346) | Sunshine Lake Pharma Co., Ltd. | 2022-07-26 |
| A Pharmacokinetic Study of Polymyxin B in Healthy Subjects and Subjects With Renal Insufficiency (NCT05359627) | TTY Biopharm | 2022-07-26 |
| Clinical Study of Cord Blood-derived CAR-NK Cells Targeting CD19 in the Treatment of Refractory/Relapsed B-cell NHL (NCT05472558) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2022-07-26 |
| Single-dose to Evaluate the Pharmacokinetics of GTX-101 and Subcutaneous Injectable Bupivacaine in Healthy Subjects (NCT05517486) | Grace Therapeutics Inc. | 2022-07-26 |
| Study to Assess Adverse Events and How Oral ABBV-990 Moves Through the Body of Adult Healthy Participants (NCT05475821) | AbbVie | 2022-07-25 |
| Study of Single Doses of SBT115301 in Healthy Participants (NCT05388981) | Sonoma Biotherapeutics, Inc. | 2022-07-25 |
| Study of SY-201 Ophthalmic Solution in Subjects With Dry Eye Disease (NCT05370495) | Seinda Pharmaceutical Guangzhou Corporation | 2022-07-25 |
| Autologous CD30.CAR-T in Combination With Nivolumab in cHL Patients After Failure of Frontline Therapy (NCT05352828) | Tessa Therapeutics | 2022-07-25 |
| In Vivo Mass Balance Study of [14C]Hemay005 (NCT05468645) | Ganzhou Hemay Pharmaceutical Co., Ltd | 2022-07-25 |
| A Study to Assess the Safety and Pharmacokinetics of HBI-002, an Oral Carbon Monoxide Therapeutic, in Healthy Volunteers (NCT03926819) | Hillhurst Biopharmaceuticals, Inc. | 2022-07-25 |
| Selinexor Plus VRd in High Risk Newly Diagnosed Multiple Myeloma (NCT05422027) | Xia Zhongjun | 2022-07-25 |
| GXR RM China BE Study (Darmstadt - Jiangsu) (NCT05463094) | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | 2022-07-25 |
| Cefiderocol Plasma Concentrations in Patients Receiving Renal Replacement Therapy (NCT05373615) | Hartford Hospital | 2022-07-25 |
| A Study of EMB-09 in Participants With Advanced or Metastatic Solid Tumors. (NCT05263180) | Shanghai EpimAb Biotherapeutics Co., Ltd. | 2022-07-25 |
| Use of Passive Myofunctional Appliances for Snoring and Mild Obstructive Sleep Apnea (NCT05497180) | University of Alberta | 2022-07-23 |
| ABSK021 Food Effect Study in Healthy Subjects (NCT05280483) | Abbisko Therapeutics Co, Ltd | 2022-07-23 |
| Clinical Trial to Compare and Evaluate the Safety and Pharmacokinetic Characteristics of DWP16001 Drug A and C (NCT05465668) | Daewoong Pharmaceutical Co. LTD. | 2022-07-22 |
| NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD) (NCT05189925) | National Institute of Allergy and Infectious Diseases (NIAID) | 2022-07-22 |
| Effects of p38 MAPK Inhibitor POLB 001 on in Vivo LPS Challenge Responses (NCT05765955) | Poolbeg Pharma plc | 2022-07-22 |
| Phase I Study of Inotuzumab With Augmented BFM Re-Induction for Patients With Relapsed/Refractory B-cell ALL (NCT03962465) | University of Virginia | 2022-07-22 |
| Clinical Trial to Study the COVAC-2 Booster Dose (for COVID-19) in Generally Healthy Adults. (NCT05226702) | University of Saskatchewan | 2022-07-22 |
| A Study of Ingested Cannabidiol in Healthy Occasional Cannabis Users (NCT05407285) | Centre hospitalier de l'Université de Montréal (CHUM) | 2022-07-22 |
| Pharmacokinetic Study of Paracetamol UNIFLASH (125 MG/1.25 ML) (NCT05406752) | Unither Pharmaceuticals, France | 2022-07-22 |
| Pharmacokinetics and Safety Assessment of VX-121/Tezacaftor/Deutivacaftor in Participants With Moderate Hepatic Impairment (NCT05437120) | Vertex Pharmaceuticals Incorporated | 2022-07-22 |
| Targeted Alpha Particle Radiotherapy for Metastatic Uveal Melanoma (NCT05496686) | Modulation Therapeutics, Inc. | 2022-07-21 |
| Study to Investigate the Mass Balance and Biotransformation of SIM0417 in Healthy Adult Chinese Male Participants (NCT05475834) | Jiangsu Simcere Pharmaceutical Co., Ltd. | 2022-07-21 |
| A Phase 1 Study of EXT608 in Healthy Adults (NCT05408663) | Extend Biosciences Inc. | 2022-07-21 |
| Anti-CD19 CAR-Engineered NK Cells in the Treatment of Relapsed/Refractory Acute Lymphoblastic Leukemia (NCT05563545) | Shanghai Simnova Biotechnology Co.,Ltd. | 2022-07-21 |
| A Study of VAC85135, a Neoantigen Vaccine Regimen, Concurrently Administered With Ipilimumab for the Treatment of Myeloproliferative Neoplasms (NCT05444530) | Janssen Research & Development, LLC | 2022-07-21 |
| Clinical Study of Mitoxantrone Hydrochloride Liposome Injection in Subjects With Acute Myeloid Leukemia (NCT05522192) | Hui Zeng | 2022-07-21 |
| A BCT Intervention for Medication Adherence Among Individuals on Statins (NCT05273736) | Northwell Health | 2022-07-21 |
| The Clinical Study of SHR-A2009 for Injection in Patients With Advanced Solid Tumors (NCT05394818) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2022-07-21 |
| Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ION464 Administered to Adults With Multiple System Atrophy (HORIZON) (NCT04165486) | Ionis Pharmaceuticals, Inc. | 2022-07-21 |
| Study of Cemiplimab - TP Induction Chemotherapy in Patients with Locally Advanced Squamous Cell Carcinoma of the Head and Neck (NCT05376553) | Krzysztof Misiukiewicz | 2022-07-20 |
| Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection (NCT05413850) | Blue Earth Therapeutics Ltd | 2022-07-20 |
| Treatment of Advanced or Metastatic Triple-negative Breast Cancer With Adoptive Therapy of PD1+ TILS (NCT05451784) | Fundacio Clinic Barcelona | 2022-07-20 |
| SAD, MAD and Food Effect Evaluation of Safety, Tolerability, and PK of AQ280 in Healthy Subjects (NCT05485779) | AQILION AB | 2022-07-20 |
| Phase 1 Study of BLB-201 Vaccine in Healthy Young and Older Adults (NCT05281263) | Blue Lake Biotechnology Inc. | 2022-07-20 |
| TSN084 Treating Patients With Advanced Malignant Tumors (NCT06386705) | Tyligand Bioscience (Shanghai) Limited | 2022-07-20 |
| Safety, Tolerability and Pharmacodynamics Evaluation of CBT-009 Eye Drop (NCT05372991) | Cloudbreak Therapeutics, LLC | 2022-07-20 |
| Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors (NCT05334329) | University of California, Irvine | 2022-07-20 |
| A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer (NCT05361174) | Iovance Biotherapeutics, Inc. | 2022-07-20 |
| Translating Metabolic Responses to Mechanical Insult Into Early Interventions to Prevent PTOA (NCT04589611) | J L Marsh | 2022-07-20 |
| Repurposing the Antipsychotic Drug Chlorpromazine as Adjuvant Therapeutic Agent for Resected Stage III Colon Cancer (NCT05433402) | Sadat City University | 2022-07-20 |
| A Study to Test How Healthy Women Tolerate Different Doses of BI 1819479 (NCT05440799) | Boehringer Ingelheim | 2022-07-20 |
| Phase I Study of Linerixibat in Adults With Moderate Hepatic Impairment and Healthy Controls (NCT05393076) | GlaxoSmithKline | 2022-07-19 |
| Photobiomodulation and Glass Ionomer Sealant as Complementary Treatment for Hypersensitivity in Molars With MIH (NCT05370417) | University of Nove de Julho | 2022-07-19 |
| Safety, Tolerability and Pharmacokinetic Characteristics Evaluation on GST-HG121 Tablets (NCT05576584) | Fujian Akeylink Biotechnology Co., Ltd. | 2022-07-19 |
| Open-label Study to Evaluate the Effects of NST-1024 on the PK of Multiple Drugs in Healthy Subjects (NCT05368831) | NorthSea Therapeutics B.V. | 2022-07-19 |
| Safety and Immunogenicity of COVID-19 Vaccine in Population Aged 18 Years and Above (NCT05552573) | Guangzhou Patronus Biotech Co., Ltd. | 2022-07-19 |
| 90Y-DOTA-anti-CD25 Basiliximab, Fludarabine, Melphalan, and Total Marrow and Lymphoid Irradiation for the Treatment of High-Risk Acute Leukemia or Myelodysplastic Syndrome (NCT05139004) | City of Hope Medical Center | 2022-07-19 |
| Open-label Safety and PK Study of BION-1301 in Japanese Healthy Subjects (NCT05508204) | Chinook Therapeutics, Inc. | 2022-07-19 |
| ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma (NCT04634357) | Eureka Therapeutics Inc. | 2022-07-19 |
| Sub-study of Belantamab Mafodotin (GSK2857916) in Combination With Nirogacestat, Lenalidomide, and Dexamethasone in Participants With RRMM (NCT07150091) | GlaxoSmithKline | 2022-07-19 |
| Study of AGEN1571 in Participants With Advanced Solid Tumors (NCT05377528) | Agenus Inc. | 2022-07-19 |
| First-in-human Study of DB-1305/BNT325 for Advanced/Metastatic Solid Tumors (NCT05438329) | DualityBio Inc. | 2022-07-19 |
| Safety and Pharmacokinetics Study of a Modified Tafasitamab IV Dosing Regimen Combined With Lenalidomide in R-R DLBCL Patients (NCT05222555) | Incyte Corporation | 2022-07-19 |
| Orthofeet: A Prospective Proof of Concept Trial to Evaluate an Innovative Pain Relief Footwear (NCT05434078) | Bijan Najafi, PhD | 2022-07-18 |
| First-in-human Trial of PhOx430, a First-in-class Acetylglucosaminyltransferase V Inhibitor, in Advanced Solid Tumours (NCT05495295) | Phost'In Therapeutics | 2022-07-18 |
| Sarcomas and DDR-Inhibition; a Combined Modality Study (NCT05116254) | The Netherlands Cancer Institute | 2022-07-18 |
| Assess Safety and Efficacy of VAD044 in HHT Patients (NCT05406362) | Vaderis Therapeutics AG | 2022-07-18 |
| Dual Anti-CD22/CD19 Chimeric Antigen Receptor-directed T Cells (CART2219.1) for Relapsed Refractory B-Lineage Leukaemia (NCT05429905) | KK Women's and Children's Hospital | 2022-07-18 |
| A Phase 1 Study of the CD73 Inhibitor(HLX23) Alone in Participants With Solid Tumor (NCT04797468) | Shanghai Henlius Biotech | 2022-07-18 |
| Combination Navitoclax, Venetoclax and Decitabine for Advanced Myeloid Neoplasms (NCT05455294) | Jacqueline Garcia, MD | 2022-07-18 |
| Targeted Investigation of Microbiome Elimination (NCT05177328) | National Institute of Allergy and Infectious Diseases (NIAID) | 2022-07-18 |
| A Clinical Study of IL13Rα2 Targeted CAR-T in Patients With Malignant Glioma (MAGIC-I) (NCT05540873) | CellabMED | 2022-07-18 |
| A Clinical Research About CD70-positive Advanced/Metastatic Solid Tumors Treated by CD70-targeted CAR-T (NCT05468190) | Chongqing Precision Biotech Co., Ltd | 2022-07-17 |
| CRTE7A2-01 TCR-T Cell for HPV-16 Positive Advanced Cervical, Anal, or Head and Neck Cancers (NCT05122221) | Corregene Biotechnology Co., Ltd | 2022-07-17 |
| Study Designed to Evaluate Safety and Efficacy of 1% Topical Formulation of KM-001 on Type 1 Punctate Palmoplantar Keratoderma or Pachyonychia Congenita Diseases (NCT05435638) | Orvida Pharma (formerly Kamari Pharma) | 2022-07-17 |
| Bioequivalence Study of Ezetimibe Tablets Under Fed Conditions in Healthy Subjects (NCT05481385) | The Affiliated Hospital of Qingdao University | 2022-07-15 |
| Annatto-derived GG for Statin-associated Myopathy (NCT05312424) | Texas Tech University Health Sciences Center | 2022-07-15 |
| Treatment With ABT-199 (Venetoclax) and Purine Analogues in Relapsed/Refractory Acute Myeloid Leukemia (NCT05506332) | University Hospital, Antwerp | 2022-07-15 |
| Effect of Probiotic Supplement on Improvement of Depressive Symptoms in Patients With Substance-Induced Depressive Disorder (NCT06790823) | Shiraz University of Medical Sciences | 2022-07-15 |
| A Phase I Clinical Study of HMPL-A83 in Patients With Advanced Malignant Neoplasm (NCT05429008) | Hutchmed | 2022-07-15 |
| Weight Management Program for Patients With First Episode Psychosis (NCT05207982) | State University of New York at Buffalo | 2022-07-15 |
| SPH3348 Tablets in a Single-center, Randomized, Open-label, Single-dose, Two-period, Two-sequence Crossover Design Food Effect Study in Healthy Chinese Subjects (NCT06652997) | West China Second University Hospital | 2022-07-15 |
| Ovarian Rejuvenation Using Platelet Rich Plasma (PRP) & Autologous Tissue Stromal Vascular Fraction (tSVF) and Cell Enriched tSVF (NCT04444245) | Black Tie Medical, Inc. | 2022-07-15 |
| Initial Investigation of [18F]P17-059 in Parkinson's Disease Patients and Healthy Volunteers (NCT03903549) | Five Eleven Pharma, Inc. | 2022-07-15 |
| Personalized Ultrasonic Brain Stimulation for Depression (NCT05301036) | University of Utah | 2022-07-15 |
| A Pharmacokinetic Study to Evaluate the Drug Interaction Between SHR0302 and CYP Substrates in Healthy Volunteers (NCT05392127) | Jiangsu HengRui Medicine Co., Ltd. | 2022-07-15 |
| A Phase 1, Two-part, Randomized Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Liquid Formulation of Tricaprilin and Matching Placebo in Healthy Subjects (NCT05408780) | Cerecin | 2022-07-14 |
| Cabazitaxel in Combination With 177Lu-PSMA-617 in Metastatic Castration-resistant Prostate Cancer (NCT05340374) | Peter MacCallum Cancer Centre, Australia | 2022-07-14 |
| An Phase I Study of YY001 in Patients with Advanced Solid Tumors (NCT06228846) | Shanghai Yuyao Biotech Co., Ltd. | 2022-07-14 |
| A Study of GZR18 Injection in Chinese Obese/Overweight Patients (NCT06256536) | Gan and Lee Pharmaceuticals, USA | 2022-07-14 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL919 in Healthy Participants (NCT05450549) | Denali Therapeutics Inc. | 2022-07-14 |
| Proof of Concept Trial of Adjuvant Activity of SWE, a Squalene-based -Oil-in-water Emulsion (NCT05035680) | Gates Medical Research Institute | 2022-07-14 |
| A Study to Evaluate the Impact of Omeprazole on the Pharmacokinetics of Sotorasib Co-administered With an Acidic Beverage in Healthy Volunteers (NCT05497557) | Amgen | 2022-07-14 |
| ASCT in Combination With C-CAR088 for Treating Patients With Ultra High-risk Multiple Myeloma (MM) (NCT05632380) | Institute of Hematology & Blood Diseases Hospital, China | 2022-07-14 |
| Autologous Tregs for Aplastic Anaemia (NCT05386264) | King's College Hospital NHS Trust | 2022-07-14 |
| Ipilimumab, Ibrutinib, and Nivolumab for the Treatment of Chronic Lymphocytic Leukemia and Richter Transformation (NCT04781855) | M.D. Anderson Cancer Center | 2022-07-14 |
| A Study of TEPEZZA® Treatment in Participants With Thyroid Eye Disease (NCT06389578) | Amgen | 2022-07-14 |
| A Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed ES-SCLC Patients in Combination With Carboplatin, Etoposide and Atezolizumab (NCT05142696) | Novartis Pharmaceuticals | 2022-07-13 |