| Clinical Trial of YH32367 in Patients With HER2 Positive Locally Advanced or Metastatic Solid Tumor (NCT05523947) | Yuhan Corporation | 2022-08-26 |
| Drug-Drug Interaction of DWP16001 in Combination With DWC202204 and DWC202205 in Healthy Male Adults (NCT05500898) | Daewoong Pharmaceutical Co. LTD. | 2022-08-26 |
| Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer (NCT05455619) | SynDevRx, Inc. | 2022-08-26 |
| A Study of LM-108 as Monotherapy or in Combination With Antitumor Therapies in Subjects With Advanced Solid Tumors (NCT05518045) | LaNova Medicines Limited | 2022-08-26 |
| A Research Study of a New Medicine NNC0113-6856 in Healthy Males (NCT05521256) | Novo Nordisk A/S | 2022-08-26 |
| Chiauranib for Advanced Solid Malignant Tumors and Relapsed/Refractory SCLC. (NCT05271292) | Chipscreen Biosciences, Ltd. | 2022-08-26 |
| A Study of AK104 in Combination With Chiauranib in Patients With Extensive Stage Small Cell Lung Cancer (NCT05505825) | Akeso | 2022-08-26 |
| The Combination of Radiotherapy, Chemotherapy and Immunotherapy in High-Risk Localized Soft Tissue Sarcoma (NCT05774275) | Fudan University | 2022-08-25 |
| Anti-CEA CAR-T Cells to Treat Colorectal Liver Metastases (NCT05240950) | Changhai Hospital | 2022-08-25 |
| Single Ascending Dose Study of SAR439459 in Adults With Osteogenesis Imperfecta (OI) (NCT05231668) | Sanofi | 2022-08-25 |
| Trial Treating Relapsed Acute Lymphoblastic Leukemia With Venetoclax and Navitoclax (NCT05192889) | St. Jude Children's Research Hospital | 2022-08-25 |
| Clinical Trial of Alpelisb and Tucatinib in Patients With PIK3CA-Mutant HER2+ Metastatic Breast Cancer. (NCT05230810) | Criterium, Inc. | 2022-08-25 |
| A Study About How ASP5354 Affects the Body in Healthy Adults and in Adults Whose Kidneys do Not Work Well (NCT05495581) | Astellas Pharma Global Development, Inc. | 2022-08-25 |
| Standardized Field Test for Marijuana Impairment II (NCT05115513) | Yale University | 2022-08-25 |
| Safety, Pharmacokinetics, and Antitumor Activity of BGB-B167 Alone and in Combination With Tislelizumab (BGB-A317) in Participants With Advanced Solid Tumors (NCT05494762) | BeiGene | 2022-08-25 |
| A Study Evaluating the Safety and Efficacy of HB0036 in Subjects With Advanced Solid Tumors (NCT05417321) | Shanghai Huaota Biopharmaceutical Co., Ltd. | 2022-08-25 |
| To Evaluate the Efficacy of TQB3823 Combined With Abiraterone and Prednisone in Metastatic Castration-resistant Prostate Cancer Patientsprednisone Acetate Tablets in Patients With Metastatic Castration-resistant Prostate Cancer (NCT05405439) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2022-08-25 |
| Gene Therapy for Cardiomyopathy Associated With Friedreich's Ataxia (NCT05445323) | Lexeo Therapeutics | 2022-08-24 |
| Effect of Evobrutinib on Pharmacokinetics of a Combined Oral Contraceptive (NCT07215806) | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | 2022-08-24 |
| A Drug-drug Interaction Study of Avapritinib and Midazolam (NCT04908176) | Blueprint Medicines Corporation | 2022-08-24 |
| A Study to Learn About the Study Medication, Zavegepant, in Healthy Volunteers (NCT06137703) | Pfizer | 2022-08-24 |
| ITIL-306 in Advanced Solid Tumors (NCT05397093) | Instil Bio | 2022-08-24 |
| Study of AMDX-2011P as a Retinal Tracer in Subjects With Neurodegenerative Diseases Associated With Amyloidogenic Proteinopathy (NCT05542576) | Amydis Inc. | 2022-08-24 |
| Safety Evaluation Study for Patients With Polycythemia Vera (NCT05074550) | Perseus Proteomics Inc. | 2022-08-24 |
| Study to Evaluate the Safety and the Pharmacokinetics of IY-NT-T (NCT05509543) | Il-Yang Pharm. Co., Ltd. | 2022-08-24 |
| Cannabinol Use in Patients With Insomnia Disorder (NCT05344170) | Woolcock Institute of Medical Research | 2022-08-24 |
| Assessing the Effect of Multiple Doses of Zibotentan on the Pharmacokinetics of Single Doses of Combined Oral Contraceptives in Healthy Female Participants of Non-childbearing Potential. (NCT05505162) | AstraZeneca | 2022-08-24 |
| A Study to Evaluate the Relative Bioavailability of Formulations of CKD-510 and to Assess the Effect of Food on the CKD-510 Tablet Formulation in Healthy Subjects (NCT05526742) | Chong Kun Dang Pharmaceutical | 2022-08-24 |
| First-Line Tarlatamab in Combination With Carboplatin, Etoposide, and PD-L1 Inhibitor in Subjects With Extensive Stage Small Cell Lung Cancer (ES-SCLC) (NCT05361395) | Amgen | 2022-08-24 |
| A Bioavailability and Food Effect Study of AZD5462 in Healthy Volunteers (NCT05512806) | AstraZeneca | 2022-08-24 |
| A Phase 1b Study to Assess the Safety, Tolerability, PK and PD of MG1113 in Hemophilia Patient (NCT05493631) | GC Biopharma Corp | 2022-08-24 |
| Silk Scaffold Surgical Incision Dressing (NCT05508945) | Mehrdad Mark Mofid | 2022-08-23 |
| A Study to Examine the Effect of Daridorexant on the Way the Body Absorbs, Distributes, and Gets Rid of Midazolam and Warfarin in Healthy Male Subjects (NCT05480488) | Idorsia Pharmaceuticals Ltd. | 2022-08-23 |
| Atezolizumab+Bevacizumab+SBRT in Unresectable HCC (NCT05096715) | Massachusetts General Hospital | 2022-08-23 |
| Phase 1b/2 Study of Liposomal Annamycin (L-Annamycin) in Subjects With Previously Treated Soft-Tissue Sarcomas (STS) With Pulmonary Metastases (NCT05518526) | Maria Sklodowska-Curie National Research Institute of Oncology | 2022-08-23 |
| Study of HRS-1167 as Monotherapy in Patients With Advanced Solid Tumors (NCT05473624) | Jiangsu HengRui Medicine Co., Ltd. | 2022-08-23 |
| A Study Explore WJ01075 Tablets in Patients With Advanced Solid Tumors (NCT05470933) | Suzhou Junjing BioSciences Co., Ltd. | 2022-08-23 |
| A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Biologic Effect of VG2025 in Patients with Solid Tumors (NCT05477849) | Shanghai Virogin Biotech Co., Ltd. | 2022-08-23 |
| Contrast Enhanced 3D Echocardiographic Quantification of Right Ventricular Volumes in Repaired CHD (NCT05186415) | Nemours Children's Clinic | 2022-08-23 |
| A Study of VS-6766 and Cetuximab in Patients With Advanced Colorectal Cancer (NCT05200442) | University of Chicago | 2022-08-22 |
| Trial to Evaluate the Safety and Immunogenicity of Priming Regimens of 426c.Mod.Core-C4b and Optional Boost Regimen With HIV Trimer BG505 SOSIP.GT1.1 gp140, Both Adjuvanted With 3M-052-AF + Alum in Healthy, Adult Participants Without HIV (NCT05471076) | National Institute of Allergy and Infectious Diseases (NIAID) | 2022-08-22 |
| A Study to Evaluate the Safety, Tolerability, and Immunogenicity of SARS-CoV-2 Variant (COVID-19 Omicron) mRNA Vaccine (Phase 1) (NCT05433194) | Suzhou Abogen Biosciences Co., Ltd. | 2022-08-22 |
| A Study to Evaluate the Safety, Tolerability, PK and PD of HNC364 Injectable Suspension (NCT05523570) | Guangzhou Henovcom Bioscience Co. Ltd. | 2022-08-22 |
| A Study on the Immune Response and Safety of an Adjuvanted Human Papillomavirus Vaccine When Given to Healthy Women 16 to 26 Years of Age (NCT05496231) | GlaxoSmithKline | 2022-08-22 |
| A Study Validating the Use of Candin as a Challenge Agent in Healthy Participants - Intervention Specific Appendix 4 (NCT05522517) | Janssen Research & Development, LLC | 2022-08-22 |
| TheraT® Vectors (Vaccines) Combined With Chemotherapy to Treat HPV16 Head and Neck Cancers (NCT05108870) | University of Chicago | 2022-08-22 |
| Controlled Human Malaria Infection Transmission Model - Phase A (NCT04280692) | University of Oxford | 2022-08-22 |
| A Phase 1, Open-label, Multicenter, Dose Escalation Study of IBI363 (PD1-IL2m) in Subjects With Advanced Solid Malignancies or Lymphomas (NCT05290597) | Innovent Biologics (Suzhou) Co. Ltd. | 2022-08-22 |
| Assessment of Elemental Impurities Level After Multiple Administration of DWJ1230 or DWB2001 in Subjects With Functional Diarrhea or Irritable Bowel Syndrome With Predominant Diarrhea. (NCT05816681) | Daewoong Pharmaceutical Co. LTD. | 2022-08-22 |
| Safety and Pharmacokinetics of GEH200486 in Healthy Volunteers (NCT05569278) | GE Healthcare | 2022-08-22 |
| Bioequivalence Study of Nirmatrelvir & Ritonavir From Copaxid 150 +100 mg Tablets (Eva Pharma, Egypt) Versus Paxlovid 150 + 100 mg Film Coated Tablets (Pfizer Europe, Belgium) (NCT05491330) | Genuine Research Center, Egypt | 2022-08-21 |
| Efficacy Of Doxycycline & Versus Rifampin In Treatment Of Rhinoscleroma (NCT05431673) | Assiut University | 2022-08-21 |
| Comparison Between Low Level Laser Therapy and Active Oxygen Releasing Gel on Wound Healing Cleft Lip Patients (NCT06765837) | Faculty of Dental Medicine for Girls | 2022-08-20 |
| Exercise for Brain Regeneration in Epilepsy (NCT05179083) | University of Southern California | 2022-08-20 |
| Study With Heparin Sodium in Subcutaneous Administration (NCT03113084) | União Química Farmacêutica Nacional S/A | 2022-08-20 |
| Phase I Clinical Trial to Evaluate the Safety and Tolerability of Ophtalmic Solution PRO-201 (NCT05470881) | Laboratorios Sophia S.A de C.V. | 2022-08-20 |
| Study of 18F-Thretide PET/CT in Patients With Prostate Cancer (NCT05516329) | First Affiliated Hospital of Fujian Medical University | 2022-08-20 |
| Drug-Drug Interaction Study of Vesatolimod in Adults With HIV-1 Who Have Very Low or Undetectable Virus Levels (NCT05458102) | Gilead Sciences | 2022-08-19 |
| BP1001-A in Patients With Advanced or Recurrent Solid Tumors (NCT04196257) | Bio-Path Holdings, Inc. | 2022-08-19 |
| A Study to Learn How Safe the Study Treatment Elinzanetant is and How it Moves Into, Through and Out of the Body When Given as Single Increasing Doses That Are Higher Than Normally Used Compared to Placebo and Moxifloxacin in Healthy Participants (NCT05481528) | Bayer | 2022-08-19 |
| A Phase 1/2 Study to Evaluate OTX-2002 in Patients with Hepatocellular Carcinoma and Other Solid Tumor Types Known for Association with the MYC Oncogene (NCT05497453) | Omega Therapeutics | 2022-08-19 |
| JAB-BX102 Monotherapy and Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors (NCT05174585) | Jacobio Pharmaceuticals Co., Ltd. | 2022-08-18 |
| Assessment Of Dose-Dependent Immunomodulatory Effect Of Alveofact With or Without Steroisd In Neonatal RDS (NCT06367881) | Ain Shams University | 2022-08-18 |
| Retentive Strength of Denture Adhesives on Various RR Ridges (NCT05063422) | Altamash Institute of Dental Medicine | 2022-08-18 |
| Phase I: Safety and Efficacy of an Injectable Follistatin Plasmid Gene Therapy in Humans (NCT06411366) | Minicircle | 2022-08-18 |
| Neratinib and Capmatinib Combination (Phase Ib/II) in Metastatic Breast Cancer and Inflammatory Breast Cancer Patients With Abnormal HER-family and c-Met Pathway Activity as Measured by the CELsignia Signaling Analysis Test (NCT05243641) | M.D. Anderson Cancer Center | 2022-08-18 |
| PET Imaging Study of α7 and α4β2-nAChR in Schizophrenia (NCT05462340) | Washington University School of Medicine | 2022-08-18 |
| Phase 1b Study of SL-172154 Administered With Combination Agent(s) in Subjects With Ovarian Cancers (NCT05483933) | Shattuck Labs, Inc. | 2022-08-18 |
| Brigatinib in Pediatric and Young Adult Patients With ALK+ ALCL, IMT or Other Solid Tumors (NCT04925609) | Princess Maxima Center for Pediatric Oncology | 2022-08-18 |
| A Study of IBI351 in Combination With Cetuximab in Subjects With KRAS G12C Mutated Metastatic Colorectal Cancer (NCT05497336) | Innovent Biologics (Suzhou) Co. Ltd. | 2022-08-18 |
| Myeloablative Conditioning Orca-T & Allogeneic Donor-Derived CD19/CD22-CAR TCells in B-Cell ALL (NCT05507827) | Stanford University | 2022-08-18 |
| A Study of JNJ-80948543, a T-cell Redirecting CD79b x CD20 x CD3 Trispecific Antibody, in Participants With Non-Hodgkin Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL) (NCT05424822) | Janssen Research & Development, LLC | 2022-08-18 |
| A Study to Investigate the Effects of Daridorexant on Nighttime Breathing in Patients With Shallow or Paused Breath During Sleep (NCT05458193) | Idorsia Pharmaceuticals Ltd. | 2022-08-17 |
| A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors (NCT05487235) | Genentech, Inc. | 2022-08-17 |
| Study to Assess Repeated Doses of INDV-2000 in Healthy Volunteers and in Treatment Seeking Individuals With Opioid Use Disorder (NCT04976855) | Indivior Inc. | 2022-08-17 |
| A Phase 1 Study of PV-001 9-valent Human Papillomavirus(HPV) Vaccine (NCT07081334) | POSVAX | 2022-08-17 |
| A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments for Adult Participants With Multiple Myeloma That is Resistant to Current Standard of Care Treatments (NCT05137054) | Regeneron Pharmaceuticals | 2022-08-17 |
| A Phase I/II Dose Escalation and Expansion Study of BST-236 Plus Venetoclax in Patients With Unfit Newly Diagnosed AML (NCT05503355) | BioSight Ltd. | 2022-08-17 |
| The Safety and Efficacy of Sequential Treatment of Ropeginterferon Alfa-2b (P1101) and Anti-PD1 in Interferon-Naive Adults With Chronic Hepatitis B or D Infection (NCT04638439) | PharmaEssentia | 2022-08-17 |
| Study of BMF-219 in Healthy Adult Subjects and in Adult Subjects With Type 2 Diabetes Mellitus (T2D) (NCT05731544) | Biomea Fusion Inc. | 2022-08-17 |
| A Study of JAB-21822 in Advanced or Metastatic NSCLC With KRAS p.G12C and STK11 Co-mutation and Wild-type KEAP1 (NCT05276726) | Allist Pharmaceuticals, Inc. | 2022-08-17 |
| Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT) (NCT05322850) | University of Florida | 2022-08-16 |
| Part 1: Dose-Finding of HSK3486 Injection In Nondependent, Recreational Central Nervous System Depressant Users (NCT07404306) | Haisco-USA Pharmaceuticals, Inc. | 2022-08-16 |
| Dose-Finding and Human Abuse Potential Study Of HSK3486 Injection In Nondependent, Recreational Central Nervous System Depressant Users (NCT05614544) | Haisco-USA Pharmaceuticals, Inc. | 2022-08-16 |
| Parametric Cardiac 18F-flutemetamol PET Imaging in ATTR Cardiomyopathy (NCT05374564) | Yale University | 2022-08-16 |
| DON in Pediatric Cerebral Malaria (NCT05478720) | Douglas Postels, MD, MS | 2022-08-16 |
| A Study to Learn About the Vepdegestrant (ARV-471, PF-07850327) in People With ER+/HER2- Locally Advanced or Metastatic Breast Cancer (BC) (NCT05463952) | Pfizer | 2022-08-16 |
| Safety, PK/PD, and Immunogenicity Study of SC ALXN2030 in Healthy Participants (NCT05501717) | Alexion Pharmaceuticals, Inc. | 2022-08-16 |
| A Clinical Trial of BP1002 in Patients With Refractory/Relapsed Acute Myeloid Leukemia (AML) (NCT05190471) | Bio-Path Holdings, Inc. | 2022-08-16 |
| Study of KBP-7072 in Healthy Male and Female Subjects (NCT05507463) | KBP Biosciences | 2022-08-16 |
| STI-6129 CD38 ADC for the Treatment of Patients With Relapsed or Refractory Systemic ALL Amyloidosis (NCT05519527) | M.D. Anderson Cancer Center | 2022-08-16 |
| A Preliminary Study to Evaluate PF-07264660 in Healthy Participants (NCT05496738) | Pfizer | 2022-08-16 |
| A Study of Mezagitamab in Adults With Primary Immunoglobulin A Nephropathy Receiving Stable Background Therapy (NCT05174221) | Takeda | 2022-08-16 |
| A Clinical Trial to Evaluate Safety, Tolerability, and Immunogenicity of Adjuvanted HIV-1 Fusion Peptide Conjugate Vaccine Alone or in Prime-Boost Regimens With Adjuvanted HIV-1 Envelope Trimer 4571 and HIV-1 Trimer 6931 Vaccines in Healthy Adults (NCT05470400) | National Institute of Allergy and Infectious Diseases (NIAID) | 2022-08-15 |
| Safety and Immunogenicity of Pneumococcal Conjugate Formulations in Healthy Adults 18 Through 49 Years of Age (NCT05489328) | Pfizer | 2022-08-15 |
| Salmonella Conjugates CVD 2000: Study of Responses to Vaccination With Trivalent Salmonella Conjugate Vaccine to Prevent Invasive Salmonella Disease (NCT05525546) | University of Maryland, Baltimore | 2022-08-15 |
| A Study in Healthy People to Compare 2 Different Formulations of BI 1015550 Taken With or Without Food (NCT05428436) | Boehringer Ingelheim | 2022-08-15 |
| A Clinical Study To Understand How Radiolabeled MK-5475 Is Taken Up By The Body, Broken Down And Then Removed From The Body in Healthy Participants (MK-5475-011) (NCT06777602) | Merck Sharp & Dohme LLC | 2022-08-15 |
| A First-In-Human Study of the Study Medicine, Called PF-07291177, in Healthy Adult Participants (NCT05434091) | Pfizer | 2022-08-15 |
| Single-Ascending Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of YJ001 in Healthy Volunteers (NCT05451667) | Yuejia Pharmaceuticals (USA), Inc. | 2022-08-15 |