| Venetoclax and Bomedemstat in Patients With Relapsed/Refractory Acute Myeloid Leukemia (NCT05597306) | Terrence J Bradley, MD | 2022-11-19 |
| Evaluate the Effect of Orelabrutinib on Cardiac Repolarization in Healthy Subjects (NCT05660720) | Beijing InnoCare Pharma Tech Co., Ltd. | 2022-11-19 |
| RIC alloBMT With Post-transplant Cyclophosphamide for Refractory Systemic Sclerosis (NCT05298358) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2022-11-18 |
| The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation (NCT05436418) | National Cancer Institute (NCI) | 2022-11-18 |
| A Study of WX390 Combined With Toripalimab in Patients With Advanced Solid Tumors (NCT06117566) | Shanghai Jiatan Pharmatech Co., Ltd | 2022-11-18 |
| Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration (NCT05380492) | Perceive Biotherapeutics, Inc. | 2022-11-17 |
| MK-8527 Single-Dose Trial in HIV-1 Infected Participants (MK-8527-004) (NCT05494736) | Merck Sharp & Dohme LLC | 2022-11-17 |
| A Study to Evaluate Administration of SBT101 Gene Therapy in Adult Patients With Adrenomyeloneuropathy (AMN) (NCT05394064) | SwanBio Therapeutics, Inc. | 2022-11-17 |
| Pharmacokinetics and Safety of Rupatadine in Participants With Hepatic Impairment Compared to Control Participants. (NCT06736340) | Noucor Health S.A. | 2022-11-17 |
| Carbon Nanoparticle-Loaded Iron [CNSI-Fe(II)] in the Treatment of Advanced Solid Tumor (NCT06048367) | Sichuan Enray Pharmaceutical Sciences Company | 2022-11-17 |
| Study of a Respiratory Syncytial Virus Candidate Encapsulated in a Lipid Nanoparticle Based Formulation in Adults Aged 18 to 50 Years and 60 Years and Older (NCT05639894) | Sanofi Pasteur, a Sanofi Company | 2022-11-17 |
| Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors (NCT05286801) | National Cancer Institute (NCI) | 2022-11-17 |
| GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2 (NCT05130255) | Y-mAbs Therapeutics | 2022-11-17 |
| Clinical Study of VG161 Combined With Nivolumab Injection in Patients With Advanced Metastatic Gastric Cancer (NCT06008925) | CNBG-Virogin Biotech (Shanghai) Ltd. | 2022-11-17 |
| Role of a CCK Receptor Antagonist Proglumide in Management of Chronic Pancreatitis (NCT05551858) | Georgetown University | 2022-11-17 |
| Pirtobrutinib (LOXO-305) Consolidation for MRD Eradication in Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL) Treated With Venetoclax (NCT05317936) | M.D. Anderson Cancer Center | 2022-11-16 |
| Safety and Tolerability of FB-001 in Healthy Adult Volunteers and Adult Subjects With Enteric Hyperoxaluria (NCT05650112) | Federation Bio Inc. | 2022-11-16 |
| A Trial of CRB4101 in Healthy Subjects (NCT05641181) | China Resources Biopharmaceutical Co., Ltd | 2022-11-16 |
| A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma (NCT05533775) | Hoffmann-La Roche | 2022-11-16 |
| Dose Escalation and Expansion Study of CPO102, an Anti-claudin 18.2 ADC in Patients With Advanced Cancers (NCT05043987) | Conjupro Biotherapeutics, Inc. | 2022-11-16 |
| A Clinical Study to Evaluate the Safety and Tolerability of JS001sc in Advanced Nasopharyngeal Carcinoma (NCT05751486) | Shanghai Junshi Bioscience Co., Ltd. | 2022-11-16 |
| A Study of LY3305677 in Participants With Obesity Or Overweight (NCT05623839) | Eli Lilly and Company | 2022-11-16 |
| A Substudy of Investigational Agents in Programmed Cell Death-1/Ligand 1 (PD-1/L1) Refractory Locally Advanced or Metastatic Urothelial Carcinoma (mUC) (MK-3475-04A) (NCT05562830) | Merck Sharp & Dohme LLC | 2022-11-16 |
| A Study of LY3437943 in Healthy Participants and Participants With Impaired Renal Function (NCT05611957) | Eli Lilly and Company | 2022-11-16 |
| Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors (NCT05053971) | National Cancer Institute (NCI) | 2022-11-16 |
| Preoperative Y-90 Radioembolization for Tumor Control and Future Liver Remnant Hypertrophy in Patients With Colorectal Liver Metastases (NCT05195710) | M.D. Anderson Cancer Center | 2022-11-16 |
| A Study of CL-197 Capsules in Healthy Participants (NCT05944848) | Henan Genuine Biotech Co., Ltd. | 2022-11-16 |
| A Phase I Study to Evaluate the Safety and Tolerability of JL15003 Injection in Patients With Recurrent Glioblastoma (NCT07497373) | Jecho Biopharmaceuticals Co., Ltd. | 2022-11-16 |
| Safety, Tolerability and Pharmacokinetics (PK) Evaluation of BZ371A, Topically Administered (NCT05332340) | Biozeus Biopharmaceutical S.A. | 2022-11-16 |
| A Phase 1 Study of ADA-011 for Subjects With Advanced Solid Tumors (NCT05601219) | Adanate, Inc | 2022-11-15 |
| Acute Dose-dependent Effects of DMT in Healthy Subjects (NCT05384678) | University Hospital, Basel, Switzerland | 2022-11-15 |
| ADME Study of [14C] Antaitavir Hasophate in Healthy Male Subjects (NCT05446233) | Sunshine Lake Pharma Co., Ltd. | 2022-11-15 |
| Study of DF9001 in Patients With Advanced Solid Tumors (NCT05597839) | Dragonfly Therapeutics | 2022-11-15 |
| A Study to Look at Safety and Tolerability of NNC0582-0001, How it is Transported Throughout the Body and How it Works in Healthy Adults (NCT05624580) | Novo Nordisk A/S | 2022-11-15 |
| Study of ZGGS18 in Patients With Advanced Solid Tumors (NCT05584800) | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 2022-11-15 |
| Pharmacokinetic Test of High-fat Diet After Oral Administration of SHR2554 in Healthy Subjects (NCT05592262) | Jiangsu HengRui Medicine Co., Ltd. | 2022-11-15 |
| Safety and Effects on Responses to Stress and Pain of Natural Medical Marijuana Products (NCT04226690) | Yale University | 2022-11-15 |
| A Study of Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of KAN-101 in Celiac Disease (ACeD-it) (NCT05574010) | Kanyos Bio, Inc., a wholly-owned subsidiary of Anokion SA | 2022-11-15 |
| Compare the Auto-injector and Pre-filled Syringe of CT-P47 in Healthy Subjects (NCT05617183) | Celltrion | 2022-11-15 |
| Oral Administration of STC-15 in Subjects With Advanced Malignancies (NCT05584111) | STORM Therapeutics LTD | 2022-11-15 |
| A Clinical Study That Will Assess the Effect of SEP-363856 or Prior Antipsychotic (PA) Standard of Care on Body-weight Associated Parameters in Subjects With Schizophrenia (NCT05542264) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2022-11-15 |
| Bioequivalence Study of Modafinil From Bravamax 200 mg Scored Tablets (Chemipharm Pharmaceutical Industries, Egypt) Versus Vigil 200 mg Tablets (Teva GmbH, Germany) (NCT05855187) | Genuine Research Center, Egypt | 2022-11-15 |
| 68Ga PET/CT Imaging in Breast Cancer Patients (NCT05622227) | Peking Union Medical College Hospital | 2022-11-15 |
| The Parallel Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of CKD-843 A (NCT05587699) | Chong Kun Dang Pharmaceutical | 2022-11-15 |
| A Study of HS248 in Patients With Advanced Solid Tumors (NCT05759234) | Hanhui Pharmaceutical Co., Ltd | 2022-11-15 |
| Effect of TPN171H on Spermatogenesis (NCT05585931) | Vigonvita Life Sciences | 2022-11-15 |
| A Study of Effect of LY3556050 on Metformin in Healthy Participants (NCT05615467) | Eli Lilly and Company | 2022-11-15 |
| A Study to Assess the Safety of MEB-1170 in Healthy Subjects (NCT05748119) | Mebias Discovery, Inc | 2022-11-15 |
| A Study of JNJ-80038114 in Participants With Advanced Stage Prostate Cancer (NCT05441501) | Janssen Research & Development, LLC | 2022-11-15 |
| A Study of Soticlestat in Healthy Adult Nondependent Recreational Drug Users With Central Nervous System (CNS) Depressant Experience (NCT05602818) | Takeda | 2022-11-15 |
| A Phase 1/2a Study Evaluating Allocetra-OTS as Monotherapy or in Combination With Anti-PD-1 Therapy for the Treatment of Advanced Solid Tumor Malignancy (NCT05581719) | Enlivex Therapeutics RDO Ltd. | 2022-11-15 |
| Relative Bioavailability of Linaprazan for the Test Formulation vs. Reference Formulation (NCT05627518) | Cinclus Pharma Holding AB | 2022-11-15 |
| Dexmedetomidine Combined With Bupivacaine for Erector Spinae Plane Block (NCT05590234) | October 6 University | 2022-11-15 |
| Drug-drug Interaction Study of XZP-3621 Tablet (NCT05586568) | Xuanzhu Biopharmaceutical Co., Ltd. | 2022-11-15 |
| YH001 Plus Envafolimab With or Without Doxorubicin in Patients With Advanced or Metastatic Sarcoma (NCT05448820) | Tracon Pharmaceuticals Inc. | 2022-11-14 |
| A Study of LY3875383 in Healthy Participants and Participants With Hypertriglyceridemia (NCT05609825) | Eli Lilly and Company | 2022-11-14 |
| A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue (NCT05634369) | Nationwide Children's Hospital | 2022-11-14 |
| AC-OLE-01-VA Tolerability Study in Healthy Participants Under Different Dosing Conditions (NCT05628636) | Cerecin | 2022-11-14 |
| Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+) (NCT05546580) | Oryzon Genomics S.A. | 2022-11-14 |
| AMG 176 With Azacitidine in Subjects With Myelodysplastic Syndrome /Chronic Myelomonocytic Leukemia (NCT05209152) | Amgen | 2022-11-14 |
| A Pharmacokinetic and Safety Study of CSTI-500 in Subjects With Prader-Willi Syndrome (NCT05504395) | ConSynance Therapeutics | 2022-11-14 |
| Assessment of the Effect of Omeprazole on Vicagrel in Healthy Subjects (NCT05651074) | Jiangsu vcare pharmaceutical technology co., LTD | 2022-11-14 |
| A 2-Part First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of CMTX-101 (NCT05629741) | Clarametyx Biosciences, Inc. | 2022-11-14 |
| Efficacy of Pentoxifylline as Add on Therapy in COVID19 Patients (NCT04433988) | Sadat City University | 2022-11-13 |
| A Study Investigating Interactions Between BMS-986322 and Rosuvastatin, Metformin and Methotrexate in Healthy Participants (NCT05615012) | Bristol-Myers Squibb | 2022-11-11 |
| Oral Gallium Maltolate for the Treatment of Relapsed and Refractory Glioblastoma (NCT04319276) | Medical College of Wisconsin | 2022-11-11 |
| Clinical Study to Investigate the Safety and Tolerance of Therapeutic BCG in Postoperative Adjuvant Therapy in Subjects With Moderate to High-risk Non-muscular Invasive Bladder Cancer (NMIBC) (NCT06350838) | Chengdu CoenBiotech Co., Ltd | 2022-11-11 |
| Antibody CC-1 in Men With Biochemical Recurrence of Prostate Cancer (NCT05646550) | University Hospital Tuebingen | 2022-11-11 |
| A Study of LY3457263 in Obese Participants (NCT05582096) | Eli Lilly and Company | 2022-11-11 |
| Clinical Study on Pharmacokinetics of FCN-437c Capsule and Its Effect on QT Interval in Healthy Subjects (NCT06290466) | Ahon Pharmaceutical Co., Ltd. | 2022-11-11 |
| A First in Human Study to Assess Safety, Tolerability, Pharmacokinetics of ABI-4334 in Healthy Subjects (NCT05569941) | Assembly Biosciences | 2022-11-11 |
| Clinical Trial to Evaluate Safety and Efficacy of Cell Therapy in Patients With Cicatricial Conjuntivitis. (NCT05520086) | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | 2022-11-11 |
| A MAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers and PHN Patients. (NCT06218784) | iN Therapeutics Co., Ltd. | 2022-11-11 |
| A Relative Bioavailability Study of LY3209590 in Healthy Participants (NCT05615532) | Eli Lilly and Company | 2022-11-11 |
| Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies (NCT05476770) | Therapeutic Advances in Childhood Leukemia Consortium | 2022-11-11 |
| PET Imaging of Vaso-Occlusive Crisis (VOC) in SCD (NCT04925492) | Enrico Novelli | 2022-11-11 |
| A Study of C-CAR088 in Patients With Relapsed or Refractory Multiple Myeloma (NCT05521802) | Shanghai AbelZeta Ltd. | 2022-11-11 |
| Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Ilaprazole and Aceclofenac (NCT05558150) | Il-Yang Pharm. Co., Ltd. | 2022-11-10 |
| Letrozole Alone Protocol Versus Using Letrozole and HCG Protocol (NCT06367712) | Egymedicalpedia | 2022-11-10 |
| A Phase I/II Dose-escalating Study of the Safety, Tolerability and Efficacy of KIO-301 Administered Intravitreally to Patients With Retinitis Pigmentosa and Choroideremia (ABACUS) (NCT05282953) | Kiora Pharmaceuticals, Inc. | 2022-11-10 |
| Cancer Preventive Vaccine Nous-209 for Lynch Syndrome Patients (NCT05078866) | National Cancer Institute (NCI) | 2022-11-10 |
| A Phase Ic/IIb Study to Evaluate the Efficacy，Safety and Pharmacokinetics of HST in Patients With CHB (NCT06122454) | Xi'an Xintong Pharmaceutical Research Co.,Ltd. | 2022-11-10 |
| Comparison of Safety and Clinical Benefit of Injections Subcutaneously Talazoparib Versus Oral Talazoparib in Patients With Solid Tumors (NCT03426254) | Center Trials & Treatment | 2022-11-10 |
| A Single and Multiple Ascending Doses Study to Evaluate the Safety and Pharmacokinetics of RBD5044 (NCT05539651) | Suzhou Ribo Life Science Co. Ltd. | 2022-11-10 |
| SGT-53, Carboplatin, and Pembrolizumab for the Treatment of Metastatic Triple Negative Inflammatory Breast Cancer (NCT05093387) | Northwestern University | 2022-11-10 |
| Proof-of-concept Study of New Imaging Diagnostic in Patients With Suspected Alzheimer's Disease (NCT05453539) | Alzeca Biosciences, Inc. | 2022-11-09 |
| Evaluate the Safety of Neuronata-R® Inj. Suspended With HypoTHermosol® FRS (HTS-FRS) in Patients With ALS (NCT06676423) | Corestemchemon, Inc. | 2022-11-09 |
| Tolerability and Effectiveness of CGB-500 Topical Ointment, 1% Tofacitinib, for the Treatment of Atopic Dermatitis (NCT05487963) | CAGE Bio Inc. | 2022-11-09 |
| Reversal of Preneoplastic Metaplasia in the Stomach With MEK Inhibitor (NCT04454476) | Vanderbilt-Ingram Cancer Center | 2022-11-09 |
| Combination of Olaparib and Navitoclax in Women with HGSC and TNBC (NCT05358639) | Sunnybrook Health Sciences Centre | 2022-11-09 |
| VIC-1911 Monotherapy in Combination With Sotorasib for the Treatment of KRAS G12C-Mutant Non-Small Cell Lung Cancer (NCT05374538) | Vitrac Therapeutics, LLC | 2022-11-09 |
| Phase I Study VG2025 as a Single Agent and in Combination Therapy With Nivolumab in Subjects With Advanced Malignant Solid Tumors (NCT05266612) | Virogin Biotech Canada Ltd | 2022-11-09 |
| Zoliflodacin Bioequivalence and Drug-Drug Interaction Study (NCT05635305) | Global Antibiotics Research and Development Partnership | 2022-11-09 |
| Study of AOC 1044 in Healthy Adult Volunteers and Participants With Duchenne Muscular Dystrophy (DMD) Mutations Amenable to Exon 44 Skipping (NCT05670730) | Avidity Biosciences, Inc. | 2022-11-09 |
| Radiodynamic Therapy (RDT) With Gliolan in Patients With First Recurrence of Brain Tumor (NCT05590689) | Universität Münster | 2022-11-09 |
| Testing an Omega-3 Fatty Acid-Based Anti-Cancer Therapy for Patients With Triple-Negative Inflammatory Breast Cancer That Has Spread to Other Parts of the Body (NCT05198843) | National Cancer Institute (NCI) | 2022-11-08 |
| Clifutinib Food Effect Study in Healthy Subjects (NCT05454098) | Sunshine Lake Pharma Co., Ltd. | 2022-11-08 |
| A Study to Assess the Safety and Pharmacokinetics of Multiple Ascending Subcutaneous Doses of DS-2325a in Healthy Subjects (NCT05583669) | Daiichi Sankyo | 2022-11-08 |
| A TQT Study of Effect of M2951 on Cardiac Repolarization (NCT07214935) | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | 2022-11-08 |
| Safety and Effects of an Investigational COVID-19 Vaccine as Booster in Healthy People (NCT05541861) | BioNTech SE | 2022-11-08 |