| Study of LM-305 in Patients With Relapsed or Refractory Multiple Myeloma (RRMM) and Other Plasma Cell Diseases (NCT05647512) | LaNova Medicines Limited | 2023-01-18 |
| A Study to Learn How the Study Medicine (Ponsegromab) is Changed and Eliminated From Healthy Chinese Adults (NCT05685264) | Pfizer | 2023-01-18 |
| A Study in Adults to Investigate the Impact of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Venglustat Compared to Participants With Normal Hepatic Function (NCT05718258) | Sanofi | 2023-01-18 |
| A Study to Evaluate How Ontamalimab Works and Assess Its Safety and Tolerability in People With Nonalcoholic Steatohepatitis With Fibrosis Stages 1 to 4 (NCT07052682) | Takeda | 2023-01-18 |
| Relative Bioavailability of Evobrutinib Tablet Batches (NCT07214922) | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | 2023-01-18 |
| Evaluating the Effects of an Oral Protein Supplement on Children's Growth Patterns (NCT06329388) | TruHeight Vitamins | 2023-01-18 |
| A Study to Compare Two Different Forms of PF-07081532 in Adults Who Are Overweight or Obese (NCT05677867) | Pfizer | 2023-01-18 |
| Study of Cord Blood-derived CAR NK Cells Targeting CD19/CD70 in Refractory/Relapsed B-cell Non-Hodgkin Lymphoma (NCT05842707) | Aibin Liang,MD,Ph.D. | 2023-01-18 |
| Responders to Rhythmic Auditory Cueing in Parkinson Disease (NCT05733819) | Boston University Charles River Campus | 2023-01-17 |
| A Research Trial Looking at the Comparability of 2 Different Concentrations of Semaglutide for the 0.5 Milligram (mg) Dose (NCT05689099) | Novo Nordisk A/S | 2023-01-17 |
| A Study to Evaluate the Safety, PK of GC2129A in Healthy Volunteers Under Fasting Conditions (NCT05703984) | GC Biopharma Corp | 2023-01-17 |
| A Study of TAS3731 in Healthy Adults (NCT05691660) | Taiho Pharmaceutical Co., Ltd. | 2023-01-17 |
| Intravenous DNase I for the Treatment of Sepsis (IDEALSepsisI) (NCT05453695) | McMaster University | 2023-01-17 |
| Phase I Clinical Trial to Evaluate the Safety of Recombinant Mycobacterium Tuberculosis Fusion Protein (EEC) in Healthy Adults Aged 18-65 and Patients With Pulmonary Tuberculosis (NCT06224608) | Chengdu CoenBiotech Co., Ltd | 2023-01-17 |
| A Study of TBio-4101 (TIL) and Pembrolizumab in Patients With Advanced Solid Tumors (NCT05576077) | Turnstone Biologics, Corp. | 2023-01-17 |
| A Study to Assess the Adverse Events and How Oral ABBV-552 Capsules Moves Through the Body of Healthy Adult Japanese and Han Chinese Participants (NCT05686980) | AbbVie | 2023-01-17 |
| A First-In-Human SAD and MAD Study to Evaluate the Safety, Tolerability, PK and PD of SC Administered ALTB-268 in Healthy Volunteers (NCT05723692) | AltruBio Inc. | 2023-01-17 |
| To Evaluate the Safety, Tolerance and Pharmacokinetics of BAT8007 for Injection in Patients With Advanced Solid Tumors (NCT05879627) | Bio-Thera Solutions | 2023-01-17 |
| Validation of Oxygen Nanosensor in Mitochondrial Myopathy (NCT04086329) | Children's Hospital of Philadelphia | 2023-01-17 |
| Intravenous BCAA for HE in ACLF (BCAA-HE-ACLF) (NCT05700695) | Post Graduate Institute of Medical Education and Research, Chandigarh | 2023-01-17 |
| A Study of FDA022-BB05 in Subjects With Advanced Solid Malignant Tumors (NCT05564858) | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. | 2023-01-16 |
| A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of RO7303509 in Participants With Systemic Sclerosis (NCT05462522) | Genentech, Inc. | 2023-01-16 |
| Safety, Tolerability and Immunogenicity of an Inactivated Whole-cell Pneumococcal Vaccine Gamma-PN3. (NCT05667740) | GPN Vaccines | 2023-01-16 |
| A Study to Measure Daridorexant in Breast Milk of Healthy Lactating Women (NCT05632393) | Idorsia Pharmaceuticals Ltd. | 2023-01-16 |
| A Study to Evaluate the Absorption, Metabolism, and Excretion (ADME) of BMS-986435 (NCT05686096) | Bristol-Myers Squibb | 2023-01-16 |
| Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 50 mg /500 mg (FDC) in Healthy Adult Male and Female Subjects Under Fed Conditions. (NCT06124547) | Galenicum Health | 2023-01-16 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALN-TTRSC04 in Healthy Subjects (NCT05661916) | Alnylam Pharmaceuticals | 2023-01-16 |
| A Study to Test How Different Doses of BI 765423 Are Taken up in the Body of Healthy Men (NCT05658107) | Boehringer Ingelheim | 2023-01-16 |
| KSD-101 Therapy for EBV-associated Haematologic Neoplasms: an Exploratory Clinical Trial (NCT05635591) | Tongji Hospital | 2023-01-16 |
| Study of SGN1 in Patients With Advanced Solid Tumor (NCT05038150) | Guangzhou Sinogen Pharmaceutical Co., Ltd | 2023-01-16 |
| A Single Arm, Prospective, Open Label, Multi Center, Phase Ib Study to Evaluate the Safety, Tolerability and Initial Efficacy of a Single Intra-tumoral Injection of IntraGel's Polymer-based Cisplatin-loaded Gel (TumoCure) in Subjects With Progressive or Radio-resistant Primary Head and Neck Tumor (NCT05200650) | IntraGel Therapeutics | 2023-01-15 |
| A Study of CodaLytic, an Intratumoral Oncolytic Virus, in Patients With Breast Cancer (NCT05600582) | Codagenix, Inc | 2023-01-15 |
| A Study of Genolair in Two Dosage Forms (Solution and Lyophilisate) and Xolair® in Healthy Volunteers (NCT06494345) | AO GENERIUM | 2023-01-15 |
| Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-TKI in Subjects With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy (NCT05695417) | Ocular Therapeutix, Inc. | 2023-01-15 |
| A Study in Healthy Chinese People to Test How Different Doses of BI 1015550 Are Taken up in the Body (NCT05633862) | Boehringer Ingelheim | 2023-01-13 |
| Single and Repeat Doses of DMT in Healthy Subjects (NCT05559931) | Algernon Pharmaceuticals | 2023-01-13 |
| PI3K Delta Inhibitor in Relapsed / Refractory Autoimmune Hemolytic Anemia Patients After Receiving Two or More Lines of Therapy (NCT05676697) | Institute of Hematology & Blood Diseases Hospital, China | 2023-01-13 |
| Testing the Safety and Effectiveness of Combining Two Drugs, PLX2853 and Trametinib in the Treatment of Advanced Uveal Melanoma (NCT05677373) | Alliance for Clinical Trials in Oncology | 2023-01-13 |
| Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 50 mg /500 mg (FDC) in Healthy Adult Male and Female Subjects Under Fasting Conditions. (NCT06124495) | Galenicum Health | 2023-01-13 |
| Study to Evaluate Safety, Tolerability, PK and the Food Effect on PK of ASC11/RTV Tablets in Healthy Subjects (NCT05718518) | Ascletis Pharmaceuticals Co., Ltd. | 2023-01-13 |
| TR64 in Patients With Advanced Solid Tumors (NCT05649345) | Tarapeutics Science Inc. | 2023-01-12 |
| Multiple Dose Study to Evaluate Drug-drug Interactions, Safety and Tolerability of NDC-002 in Healthy Volunteers (NCT06090474) | Dr. Noah Biotech Inc. | 2023-01-12 |
| Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal Cancer (NCT05631574) | Biomea Fusion Inc. | 2023-01-12 |
| FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3 (NCT05614739) | Eli Lilly and Company | 2023-01-12 |
| Study on Single and Multiple Atomization Inhalation of HRS-9821 Suspension for Inhalation in Healthy Subjects and COPD Patients (NCT05622864) | Guangdong Hengrui Pharmaceutical Co., Ltd | 2023-01-12 |
| A Study of Modakafusp Alfa in Adult Participants With Multiple Myeloma (NCT05556616) | Teva Branded Pharmaceutical Products R&D LLC | 2023-01-12 |
| Feasibility of Implementing Acupuncture Into Federally Qualified Health Center Among Breast Cancer Survivors (NCT05615753) | University of Illinois at Chicago | 2023-01-12 |
| Oral Axl/Mer/CSF1R Selective Tyrosine Kinase Inhibitor Q702 in Combination With Pembrolizumab in Patients With Selected Advanced Solid Tumors (NCT05438420) | Qurient Co., Ltd. | 2023-01-12 |
| A Trial to Learn if Single Ascending Intravenous (IV) Doses of REGN7508 Are Safe and Well Tolerated, and How it Works in the Body of Healthy Adult Participants (NCT05603195) | Regeneron Pharmaceuticals | 2023-01-12 |
| Navitoclax in Relapsed or Refractory High-Risk Myelodysplastic Syndrome (NCT05564650) | Thomas Jefferson University | 2023-01-12 |
| Absorption, Metabolism, Excretion and Absolute Bioavailability of EDG-5506 in Healthy Volunteers (NCT05730842) | Edgewise Therapeutics, Inc. | 2023-01-12 |
| Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB054707 in Participants With Normal and Impaired Renal Function and Participants on Hemodialysis (NCT05624723) | Incyte Corporation | 2023-01-12 |
| A Phase I/II Study of LM-101 Injection in Patients With Advanced Malignant Tumors (NCT05615974) | LaNova Medicines Limited | 2023-01-11 |
| Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer (NCT05573126) | Ellipses Pharma | 2023-01-11 |
| A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of BA1301 in Advanced Solid Tumors. (NCT06927349) | Shandong Boan Biotechnology Co., Ltd | 2023-01-11 |
| Dose Escalation and Expansion Study of HM97662 in Advanced or Metastatic Solid Tumors (NCT05598151) | Hanmi Pharmaceutical Company Limited | 2023-01-11 |
| Diazepam Trial in GAD65 Associated Epilepsy (NCT05361447) | Mayo Clinic | 2023-01-11 |
| An Open-label, Adaptive Design, Positron Emission Tomography Study in Healthy Male Participants to Characterize Receptor Occupancy by MIJ821 in the Brain (NCT05666687) | Novartis Pharmaceuticals | 2023-01-11 |
| First in Human Study of IMGN151 in Recurrent Gynaecological Cancers (NCT05527184) | AbbVie | 2023-01-11 |
| A Dose Escalation Study of Proton and Carbon Ion Irradiation for HER2 Positive and Triple Negative Breast Cancer (NCT05692661) | Shanghai Proton and Heavy Ion Center | 2023-01-10 |
| To Evaluate the Safety, Tolerability and Pharmacokinetic of SAL0133 Tablets in Chinese Adult Healthy Subjects (NCT07030504) | Shenzhen Salubris Pharmaceuticals Co., Ltd. | 2023-01-10 |
| Food Effect Study of BMS-984923 in Healthy Older Adult Volunteers (NCT05817643) | Allyx Therapeutics | 2023-01-10 |
| Immunotherapy in Combination With Chemoradiotherapy in Unresectable Locally Advanced Esophageal Cancer (NCT06173986) | Shanghai Chest Hospital | 2023-01-10 |
| Neo-T in Treating Patients With Advanced Solid Tumors(GI-NeoT-03) (NCT05798533) | BGI, China | 2023-01-10 |
| A Pharmacokinetic Study of Mitapivat in Participants With Moderate Hepatic Impairment Compared to Matched Healthy Control Participants With Normal Hepatic Function (NCT05610657) | Agios Pharmaceuticals, Inc. | 2023-01-10 |
| Evaluation of IGM-7354 in Adults With Relapsed and/or Refractory Cancer (NCT05702424) | IGM Biosciences, Inc. | 2023-01-10 |
| A Study of Multiple Ascending Doses MY008211A in Healthy Adults (NCT05828472) | Wuhan Createrna Science and Technology Co., Ltd | 2023-01-10 |
| Comparing Effects of Beetroot Juice and Mediterranean Diet on Liver Enzymes and Sonography in Patients With NAFLD (NCT05909631) | Sulaimani Polytechnic University | 2023-01-10 |
| The Anti-fungal Effect of Miconazol Versus Miconazol-Loaded Chitosan Nanoparticles (NCT06072716) | Yasmine gamil | 2023-01-10 |
| Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics of a Single 3 mg Cytisinicline Dose (NCT05631938) | Achieve Life Sciences | 2023-01-10 |
| Red Light Photobiomodulation and Topical Disinfectants (NCT05797818) | Ondine Biomedical Inc. | 2023-01-10 |
| Assessment of Safety and Immunogenicity of R21/Matrix-M™ in African Children Living With HIV (NCT05385510) | University of Oxford | 2023-01-10 |
| Early Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same Donor (NCT05508009) | Alice Bertaina | 2023-01-10 |
| Pembrolizumab in Combination With Chemotherapy and Image-Guided Surgery for Malignant Pleural Mesothelioma (MPM) (NCT03760575) | Abramson Cancer Center at Penn Medicine | 2023-01-10 |
| A Study of Absorption, Metabolism, and Elimination CC-90010 in Participants With Advanced Solid Tumors (NCT05678283) | Bristol-Myers Squibb | 2023-01-09 |
| Phase 1b/2 Study of TTI-101 in Combination for Patients With Metastatic Hormone Receptor-Positive and HER2-Negative Breast Cancer (NCT05384119) | Tvardi Therapeutics, Incorporated | 2023-01-09 |
| Phase 1b/2a Study of GSBR-1290 in Adult Overweight or Obese Healthy Subjects and Subjects With Type 2 Diabetes Mellitus (NCT05762471) | Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics | 2023-01-09 |
| A Pharmacokinetic Study of DW6013 (FDC of Linagliptin and Metformin) in Healthy Adult Volunteers in Fed Condition (NCT05874180) | Dong Wha Pharmaceutical Co. Ltd. | 2023-01-09 |
| In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors (NCT04616248) | University of Southern California | 2023-01-09 |
| A Study to Investigate the Antitumor Activity, Safety, Tolerability, and Pharmacokinetics of BGB-A445 in Combination With Tislelizumab in Participants With Select Advanced Solid Tumors. (NCT05661955) | BeiGene | 2023-01-09 |
| BXQ-350 in Newly Diagnosed Metastatic Colorectal Carcinoma (NCT05322590) | Bexion Pharmaceuticals, Inc. | 2023-01-09 |
| Study Of ATRN-119 In Patients With Advanced Solid Tumors (NCT04905914) | Aprea Therapeutics | 2023-01-09 |
| A Study of ALRN-6924 for Protection of Chemotherapy-Induced Side Effects in Patients With TP53-Mutant Breast Cancer (NCT05622058) | Aileron Therapeutics, Inc. | 2023-01-09 |
| Safety and Efficacy of Lenvatinib and Anti-PD1 Antibody Combined With Radiotherapy Neoadjuvant Treatment for Resectable Hepatocellular Carcinoma With PVTT (NCT05225116) | Beijing Tsinghua Chang Gung Hospital | 2023-01-08 |
| A Phase I Study in Healthy Participants (NCT06277167) | Kexing Biopharm Co., Ltd. | 2023-01-07 |
| A Study to Assess the Effects on the Single-Dose Drug Levels of Mavacamten in Healthy Participants (NCT05658146) | Bristol-Myers Squibb | 2023-01-06 |
| Study Assessing the Feasibility, Safety and Efficacy of Genetically Engineered Glucocorticoid Receptor Knock Out Virus Specific CTL Lines for Viral Infections in Immunosuppressed Cancer Patients (NCT05101213) | M.D. Anderson Cancer Center | 2023-01-06 |
| Multiple Ascending Dose Study of TMP-301 in Healthy Subjects (NCT06025396) | Tempero Bio, Inc. | 2023-01-06 |
| A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Characteristics, and Preliminary Efficacy of HLX35 in Combination With HLX10 in Patients With Advanced or Metastatic Solid Tumors (NCT05442996) | Shanghai Henlius Biotech | 2023-01-06 |
| Study of INCA32459 a LAG-3 and PD-1 Bispecific Antibody in Participants With Select Advanced Malignancies (NCT05577182) | Incyte Corporation | 2023-01-05 |
| Study Evaluating the Safety and Feasibility of Platelet-rich Plasma to Treat Facetogenic Low Back Pain (NCT05250947) | Matthew Pingree | 2023-01-05 |
| Treatment With Human Umbilical Cord-derived Mesenchymal Stromal Cells in Systemic Sclerosis (NCT04356287) | Marie Hudson, MD | 2023-01-05 |
| the Effect of Viewing Idealized Smile Images Versus Nature Images Via Social Media on Immediate Facial Satisfaction in Young Adults: a Randomized Controlled Trial. (NCT05798650) | Altamash Institute of Dental Medicine | 2023-01-05 |
| Oxygen Atomizing Inhalation of EGCG in the Treatment Interstitial Pneumonia in Cancer Patients (NCT05758571) | Shandong Cancer Hospital and Institute | 2023-01-05 |
| Phase I Clinical Study of BL-M07D1 in Locally Advanced or Metastatic Digestive Tract Tumors and Other Solid Tumors (NCT05631964) | Sichuan Baili Pharmaceutical Co., Ltd. | 2023-01-05 |
| A Study of the Effect of Daridorexant on Nighttime Body Posture, the Noise Level Required to Wake up, and the Ability to Remember Words Previously Presented (NCT05702177) | Idorsia Pharmaceuticals Ltd. | 2023-01-05 |
| Bioequivalence Study of INS062 and Pharmacokinetics and Pharmacokinetics Study of Single Injection of HR20014 in Healthy Subjects (NCT05719961) | Jiangsu HengRui Medicine Co., Ltd. | 2023-01-05 |
| A Bioequivalence Study of Advil PM Liqui-Gels Minis (Ibuprofen/Diphenhydramine Hydrochloride 200 mg/25 mg) Compared to the Current Marketed Advil PM Liqui-Gels (Ibuprofen/Diphenhydramine Hydrochloride 200 mg/25 mg) in Healthy Adult Subjects Under Fasted Conditions (NCT05674721) | HALEON | 2023-01-05 |
| Belantamab Mafadotin Maintenance Therapy After Salvage Autologous Hematopoietic Cell Transplantation in Patients With Relapse Refractory Multiple Myeloma (NCT05065047) | M.D. Anderson Cancer Center | 2023-01-05 |
| Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric Diffuse Intrinsic Pontine Gliomas (DIPG) (NCT05630209) | InSightec | 2023-01-04 |