| A Study of Multiple Ascending Doses of GSBR-1290 in Japanese and Non-Japanese Healthy Participants (NCT05893043) | Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics | 2023-04-24 |
| A Study to Evaluate the Pharmacokinetics of HSK21542 in Subjects With Renal Impairment (NCT05947097) | Haisco Pharmaceutical Group Co., Ltd. | 2023-04-24 |
| A Study in Healthy Men to Test How BI 1291583 is Processed in the Body (NCT05833035) | Boehringer Ingelheim | 2023-04-24 |
| Topical Dermaprazole for Radiation Dermatitis in Breast Cancer Patients (TOPAZ) (NCT05269160) | Baylor College of Medicine | 2023-04-24 |
| A Study of TY-1091 in Patients With Advanced Solid Tumors (NCT05675605) | TYK Medicines, Inc | 2023-04-24 |
| A Study of BPI-460372 in Advanced Solid Tumor Patients (NCT05789602) | Betta Pharmaceuticals Co., Ltd. | 2023-04-24 |
| Clinical Study to Evaluate the Safety, Tolerability and the Concentration of the BDP (Beclomethasone Dipropionate), Active Metabolite of BDP, FF( Formoterol Fumarate) and GB (Glycopyrronium Bromide), After Inhalation of CHF 5993 at Two Different Doses and QVAR® (NCT05898984) | Chiesi Farmaceutici S.p.A. | 2023-04-24 |
| TR115 in Patients With Relapsed / Refractory Non-Hodgkin's Lymphoma or Advanced Solid Tumors (NCT05650580) | Tarapeutics Science Inc. | 2023-04-23 |
| Autologous CD19 CAR-T Cell Therapy (SYNCAR-001) + Orthogonal IL-2 (STK-009) in Subjects With CD19+ Hematologic Malignancies (NCT05665062) | Synthekine | 2023-04-23 |
| Oral Supplement in Older Adults to Support Physical Fitness and Mental Well-being (NCT05878847) | Aberystwyth University | 2023-04-22 |
| Investigating the Clinical Impact of a Novel Adipose Allograft Matrix on Knee Fat Pad Impingement Treatment (NCT05880888) | Ohio State University | 2023-04-22 |
| Phase 1/1b Study of TLC-6740 in Healthy Subjects and Subjects With Obesity, With or Without Diabetes (NCT05822544) | OrsoBio, Inc | 2023-04-22 |
| A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-348(5) (NCT05749861) | Chong Kun Dang Pharmaceutical | 2023-04-22 |
| External Body Pressure in Heart Failure With Preserved Ejection Fraction (NCT05764564) | Duke University | 2023-04-21 |
| Combinatory Rehabilitation Used for Substantially Helping Individuals With Traumatic Brain Injury (NCT05716048) | Kessler Foundation | 2023-04-21 |
| A Study of ES014 (Anti-CD39/TGF-β Bispecific Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors (NCT05381935) | Elpiscience Biopharma, Ltd. | 2023-04-21 |
| SIRT With Tremelimumab and Durvalumab for Resectable HCC (NCT05701488) | Jiping Wang, MD, PhD | 2023-04-21 |
| SAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (NCT05902962) | PYC Therapeutics | 2023-04-20 |
| A Trial to Study if REGN5837 in Combination With Odronextamab is Safe for Adult Participants With Aggressive B-cell Non-Hodgkin Lymphomas (NCT05685173) | Regeneron Pharmaceuticals | 2023-04-20 |
| A Study of TY-2136b in Patients With Advanced Solid Tumors Harboring ALK, ROS1 or NTRK1-3 Alterations (NCT05769075) | TYK Medicines, Inc | 2023-04-20 |
| Comparing of the PK, PD, Safety and Immunogenicity of HS-20090 and Xgeva® in Healthy Adults (NCT05777109) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2023-04-20 |
| A Study To Evaluate the Safety of XW001 Inhalation in Children With RSV (NCT05779995) | Hangzhou Sciwind Biosciences Co., Ltd. | 2023-04-20 |
| Cannabidiol (CBD) in Adults With ASD (NCT05015439) | Johns Hopkins University | 2023-04-20 |
| An ADME Study of [14C]AZD0780 in Healthy Male Subjects (NCT05817461) | AstraZeneca | 2023-04-19 |
| Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies (NCT05783622) | Janux Therapeutics | 2023-04-19 |
| Study of DPPG2-TSL-DOX Combined With Hyperthermia in Soft Tissue Sarcoma (NCT05858710) | Thermosome GmbH | 2023-04-19 |
| Phase I/IIa Study of BR1733 in Subjects With Advanced Cancers (NCT05749549) | Shanghai Blueray Biopharma Co., Ltd. | 2023-04-19 |
| Safety Study of Intravenous Ertapenem in Combination With Zidebactam (WCK 6777) (NCT05645757) | National Institute of Allergy and Infectious Diseases (NIAID) | 2023-04-19 |
| IDO and PD-L1 Peptide Based Immune-Modulatory Therapeutic (IO102-IO103) in Combination With Pembrolizumab for BCG-Unresponsive or Intolerant, Non-Muscle Invasive Bladder Cancer (NCT05843448) | University of California, Davis | 2023-04-19 |
| A Bioequivalence Study of Two Ibuprofen Arginine Granules 400 mg Formulations Under Fasting and Fed Conditions in Chinese Healthy Adult Subjects (NCT05737069) | HALEON | 2023-04-19 |
| Care Partner-Assisted Diabetes Self-Management Through Linking Continuous Glucose Monitoring With Mobile Health: Improving Outcomes for Older Adults With Mild Cognitive Impairment (NCT05601583) | NYU Langone Health | 2023-04-19 |
| Study of XNW5004 Tablet in Combination With Enzalutamide in Subjects With Metastatic Castration-Resistant Prostate Cancer (NCT06702995) | Evopoint Biosciences Inc. | 2023-04-19 |
| Study of SGN1 Administered Via Intratumoral Injection in Patients With Advanced Solid Tumor (NCT05103345) | Guangzhou Sinogen Pharmaceutical Co., Ltd | 2023-04-19 |
| Pharmacokinetics and Safety of HRS-8427 in Healthy Volunteers and in Patients With Impaired Renal Function (NCT07070375) | Jiangsu HengRui Medicine Co., Ltd. | 2023-04-19 |
| A Study to Learn About a Type of Pneumococcal Vaccine With a New Ingredient (PF-07872411) Intended to Enhance the Effects of the Vaccine Which is Given to Adults (NCT05831124) | Pfizer | 2023-04-19 |
| Safety and Tolerability, Pharmacokinetic, and Pharmacodynamic Study of ALXN1920 in Healthy Participants (NCT05751642) | Alexion Pharmaceuticals, Inc. | 2023-04-19 |
| Zuranolone Pharmacokinetics (PK) and Safety Study Adolescent Participants With Major Depressive Disorder (MDD) (NCT05655507) | Biogen | 2023-04-19 |
| A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors (NCT05787587) | IDEAYA Biosciences | 2023-04-18 |
| A Study to Investigate the Safety, Tolerability, and Efficacy of BxC-I17e Single and Multiple Dose SC Injection in Patients With Moderate to Severe Atopic Dermatitis (NCT06055361) | Brexogen Inc. | 2023-04-18 |
| Phase 1, Dose Escalation Study to Evaluate of Safety, Pharmacokinetics and Pharmacodynamics of Liposomal Bupivacaine 13.3 Administered Via a Single Intrathecal Injection to Healthy Volunteers (NCT05456490) | Pacira Pharmaceuticals, Inc | 2023-04-18 |
| A Study to Assess the Relative Bioavailability of Immediate Release Formulations of ABBV-903 in Healthy Adult Participants (NCT05836506) | AbbVie | 2023-04-18 |
| Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies (NCT05786924) | Institut de Recherches Internationales Servier | 2023-04-18 |
| VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors (NCT04796012) | University of Texas Southwestern Medical Center | 2023-04-18 |
| Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma (NCT05539430) | Legend Biotech USA Inc | 2023-04-18 |
| Impact of Early ADL Participation on Outcomes Post DRF (NCT05650996) | George Washington University | 2023-04-18 |
| A Study of SHR-4602 in Subjects With Advanced Malignant Solid Tumors (NCT05819684) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2023-04-18 |
| Safety and Immune Responses After Vaccination With Two Investigational RNA-based Vaccines Against Tuberculosis in Healthy Volunteers (NCT05537038) | BioNTech SE | 2023-04-18 |
| A Phase I Study of RGT-419B in Patients With HR-Positive, HER2-Negative Advanced Breast Cancer or Other Solid Tumors (NCT06299124) | Regor Pharmaceuticals Inc. | 2023-04-17 |
| A Phase I Study of QLS12004 in Patients With Advanced Solid Tumors (NCT05829616) | Qilu Pharmaceutical Co., Ltd. | 2023-04-17 |
| A Phase 1 Study of SAIL66 in Patients With CLDN6-positive Locally Advanced or Metastatic Solid Tumors (NCT05735366) | Chugai Pharmaceutical | 2023-04-17 |
| Single Ascending Dose Study of NRS 033 in Healthy Volunteers (NCT05724797) | Nirsum Labs | 2023-04-17 |
| MK-8510 Monotherapy for the Treatment of Anti-retroviral naïve Human Immunodeficiency Virus Type 1 (HIV-1) Infected Participants (MK-8510-002) (NCT05700734) | Merck Sharp & Dohme LLC | 2023-04-17 |
| Efficacy of Daratumumab to Overcome Platelet Transfusion Refractoriness in Patients with Aplastic Anemia (NCT05832216) | Institute of Hematology & Blood Diseases Hospital, China | 2023-04-17 |
| A Study of Milademetan Administration on Cardiac Repolarization in Healthy Subjects (NCT05758818) | Rain Oncology Inc | 2023-04-17 |
| Rivastigmine Bioequivalence Trial With Multiple Applications of Transdermal Patches (9.5 mg/24 h) (NCT05883124) | SocraTec R&D GmbH | 2023-04-17 |
| First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors (NCT05768139) | Eli Lilly and Company | 2023-04-17 |
| Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade Glioma (NCT05561374) | Oblato, Inc. | 2023-04-17 |
| Open-label Trial to Evaluate the Effect Carbamazepine on Darigabat Pharmacokinetics in Healthy Adult Participants (NCT05824143) | Cerevel Therapeutics, LLC | 2023-04-17 |
| A Clinical Study Evaluating the Safety of Peptide Receptor Radionuclide Therapy (PRRT) With 177Lu-DOTA0-Tyr3-Octreotate in Children With Refractory or Recurrent Neuroblastoma Expressing Somatostatin Receptors. (NCT03966651) | Institut Claudius Regaud | 2023-04-17 |
| Study of TFX06 in Women With Advanced Breast Cancer. (NCT05927779) | Zhejiang Yangli Pharmaceutical Technology Co., Ltd. | 2023-04-17 |
| Voxelotor CYP and Transporter Cocktail Interaction Study (NCT05981365) | Pfizer | 2023-04-17 |
| Phase 1 Clinical Trial of Lenvatinib, Pembrolizumab and Hypofractionated Pelvic Radiation Therapy for pMMR Recurrent/Unresectable Endometrial Carcinoma (NCT05603910) | Aaron Wolfson | 2023-04-15 |
| Efficacy and Safety of Baricitinib in Neuromyelitis Optica Spectrum Disorders (NCT05792462) | Tianjin Medical University General Hospital | 2023-04-15 |
| A Phase 1 Study of JV-213 Autologous CD79b-targeting Chimeric Antigen Receptor T-cell Therapy in Adults With Relapsed or Refractory B-cell Lymphomas (NCT05773040) | M.D. Anderson Cancer Center | 2023-04-14 |
| A Study of ELI-002 7P in Subjects With KRAS/NRAS Mutated Solid Tumors (NCT05726864) | Elicio Therapeutics | 2023-04-14 |
| A Phase 1, Open-Label Study to Evaluate the Effect of a Low-Fat Meal and Multiple Doses of Ciprofloxacin on the Pharmacokinetics of Vorasidenib in Healthy Subjects (NCT05843708) | Servier Bio-Innovation LLC | 2023-04-14 |
| A Phase I/II Clinical Trial of LBL-033 in the Treatment of Advanced Malignant Tumors (NCT05779163) | Nanjing Leads Biolabs Co.,Ltd | 2023-04-14 |
| Study of AK119 Combined With AK112 in Patients With Advanced Solid Tumors (NCT05689853) | Akeso | 2023-04-14 |
| A Study in Healthy Men to Test How Itraconazole Influences the Amount of Zongertinib (BI 1810631) in the Blood (NCT05833139) | Boehringer Ingelheim | 2023-04-14 |
| A Study of mRNA-based Influenza and SARS-CoV-2 (COVID-19) Multi-component Vaccines in Healthy Adults (NCT05827926) | ModernaTX, Inc. | 2023-04-14 |
| A Two-part Study to Investigate the Effects in Adults of Two Doses of Golexanolone in Patients With Primary Biliary Cholangitis (PBC) With Fatigue and Cognitive Dysfunction (NCT07304843) | Umecrine Cognition AB | 2023-04-14 |
| Study to Evaluate the Safety, Tolerance, Pharmacokinetics Characteristics of PA3670 Tablets in Chinese Healthy Subjects (NCT05851261) | Zhejiang Palo Alto Pharmaceuticals, Inc. | 2023-04-13 |
| A First-in-human, Phase I, Open-label, Multicenter Study of NM1F(Anti-PVRIG) in Patients With Advanced Solid Tumors (NCT05746897) | Hefei TG ImmunoPharma Co., Ltd. | 2023-04-13 |
| A Study of TQB2930 for Injection Monotherapy or Combination Therapy in Patients With Recurrent/Metastatic Breast Cancer (NCT06202261) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2023-04-13 |
| A Clinical Trial of PRAX-222 in Pediatric Participants With Early Onset SCN2A Developmental and Epileptic Encephalopathy (NCT05737784) | Praxis Precision Medicines | 2023-04-13 |
| A Study to Learn About How Itraconazole Affects the Blood Level of Study Medicine (PF-07817883) in Healthy Adults. (NCT05822440) | Pfizer | 2023-04-13 |
| HPV-T in HPV-16 Positive Recurrent or Metastatic Solid Tumors (NCT05895370) | BGI, China | 2023-04-13 |
| To Compare the Safety and PK/PD Characteristics of Subjects With Between Hepatic Impairment and Normal Hepatic Function (NCT05747664) | Daewoong Pharmaceutical Co. LTD. | 2023-04-13 |
| Immunotherapy with Autologous Tregs in T1DM (NCT06708780) | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 2023-04-12 |
| A Study on the Effect of Nipocalimab on Vaccine Responses in Healthy Participants (NCT05827874) | Janssen Research & Development, LLC | 2023-04-12 |
| Substudy 01 - Safety and Immunogenicity of One Monovalent Modified mRNA Vaccine Encoding Influenza Hemagglutinin With LNP, in Adult Participants Aged 18 to 49 Years and 60 Years and Above (NCT05829356) | Sanofi Pasteur, a Sanofi Company | 2023-04-12 |
| ISP-001: Sleeping Beauty Transposon-Engineered B Cells for MPS I (NCT05682144) | Immusoft of CA, Inc. | 2023-04-12 |
| FiH Study to Assess Safety and PK of SAD and MAD of ANT3310 Alone and in Combination With Meropenem in Healthy Subjects (NCT05905913) | Antabio | 2023-04-12 |
| A Study of the Effect of Food on LY3537982 in Healthy Participants (NCT05824858) | Eli Lilly and Company | 2023-04-12 |
| Promising ROd-cone DYstrophy Gene therapY (NCT05748873) | SparingVision | 2023-04-12 |
| Pharmacokinetic Characteristics of Subjects with Hepatic Insufficiency and Healthy Subjects (NCT05711797) | Nanjing Zenshine Pharmaceuticals | 2023-04-12 |
| A Research Study Looking at How Cagrilintide Works on the Heart Rhythm in Healthy Participants (NCT05804162) | Novo Nordisk A/S | 2023-04-12 |
| NEROFE and Doxorubicin in KRAS-mutated ST2-positive Solid Tumors (NCT05661201) | Georgetown University | 2023-04-12 |
| A Study to Investigate the Potential Drug Interactions Between ALXN2080 and Rosuvastatin and Metformin in Healthy Adult Participants (NCT06160414) | Alexion Pharmaceuticals, Inc. | 2023-04-12 |
| A Study to Evaluate the Effect of VX-548 on the QT/QTc Interval in Healthy Participants (NCT05818852) | Vertex Pharmaceuticals Incorporated | 2023-04-12 |
| Donor Enriched Activated NK Cell Infusion Post Haploidentical Stem Cell Transplant for Refractory Myeloid Malignancies (NCT05375253) | University of Nebraska | 2023-04-12 |
| A Study Evaluating Efficacy and Safety of Multiple Treatment Combinations in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck (Morpheus-Head and Neck Cancer) (NCT05459129) | Hoffmann-La Roche | 2023-04-12 |
| A Rollover Study of CC-122 (NCT05688475) | Bristol-Myers Squibb | 2023-04-11 |
| Drug Interaction Assessment of GSK3882347 in Healthy Participants Aged 18 to 65 Years (NCT05760261) | GlaxoSmithKline | 2023-04-11 |
| Intracavitary Photodynamic Therapy as an Adjuvant to Resection of Glioblastoma or Gliosarcoma Using IV Photobac® (NCT05363826) | Photolitec LLC | 2023-04-11 |
| A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Elarekibep in Healthy Japanese Subjects (NCT05794672) | AstraZeneca | 2023-04-11 |
| Study to Assess EXS21546 in Combination in Patients With Advanced Solid Tumours (NCT05920408) | Exscientia AI Limited | 2023-04-11 |
| A Clinical Trial to Evaluate the Effect of Itraconazole and Rifampicin on ABSK021 (NCT06089733) | Abbisko Therapeutics Co, Ltd | 2023-04-11 |
| Fluorescence Imaging With Indocyanine Green(ICG) in Endoscopic Spinal Surgery (NCT05808140) | Zhongnan Hospital | 2023-04-11 |
| A Clinical Trial to Compare and Evaluate the Safety and Pharmacokinetics of CKD-378 (NCT05741437) | Chong Kun Dang Pharmaceutical | 2023-04-11 |