| A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations (NCT05788536) | Regeneron Pharmaceuticals | 2023-06-27 |
| Psilocybin-Assisted Therapy for the Treatment of Cancer-Related Anxiety in Patients With Metastatic Cancer (NCT05847686) | University of Washington | 2023-06-27 |
| Treatment of Ano-perineal Fistulas Resistant to Surgical Treatment with a Gel and Plug of Wharton's Jelly (NCT05638139) | TBF Genie Tissulaire | 2023-06-27 |
| Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency. (NCT05838768) | Novartis Pharmaceuticals | 2023-06-27 |
| Psilocybin-assisted CBT for Depression (NCT05227612) | University of California, Los Angeles | 2023-06-27 |
| Study to Assess PDM608 in Healthy Adult Subjects (NCT05950906) | Calibr, a division of Scripps Research | 2023-06-27 |
| A Study to Test How Well Different Doses of Obrixtamig (BI 764532) in Combination With Ezabenlimab Are Tolerated by People With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3 (NCT05879978) | Boehringer Ingelheim | 2023-06-27 |
| A Study of Remimazolam Tosilate for Prolonged Sedation in the ICU (NCT05913336) | Jiangsu HengRui Medicine Co., Ltd. | 2023-06-27 |
| Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas (NCT05389423) | National Cancer Institute (NCI) | 2023-06-27 |
| Cell Therapy With Treg Cells Obtained From Thymic Tissue (thyTreg) to Control the Immune Hyperactivation Associated With COVID-19 and/or Acute Respiratory Distress Syndrome (THYTECH2) (NCT06052436) | Hospital General Universitario Gregorio Marañon | 2023-06-27 |
| A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma (NCT05698524) | University of Nebraska | 2023-06-26 |
| Evaluation of 89Zr-TLX250 PET/CT in Chinese Patients With Indeterminate Renal Masses or Suspected Recurrent Renal Clear Cell Carcinoma (NCT05861778) | Telix Pharmaceuticals (Innovations) Pty Limited | 2023-06-26 |
| Pharmacokinetics of Intravenous Difelikefalin in Chinese Adult Subjects on Haemodialysis (NCT05885763) | Vifor Fresenius Medical Care Renal Pharma | 2023-06-26 |
| Study of BC3195 Monotherapy in Patients With Advanced Solid Tumors (NCT05957471) | Biocity Biopharmaceutics Co., Ltd. | 2023-06-26 |
| A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK121-NX in Patients With Advanced Solid Tumors (NCT05627063) | Abbisko Therapeutics Co, Ltd | 2023-06-26 |
| A Study To Evaluate The Effect Of A Supratherapeutic Dose Of Elpipodect (MK-8189) On The QTc Interval In Participants With Schizophrenia (MK-8189-019) (NCT05893862) | Merck Sharp & Dohme LLC | 2023-06-26 |
| Study Evaluating Safety and Tolerability of Escalating Single and Multiple Doses of PIPE-791 and Food Effect in Healthy Volunteers (NCT05983939) | Contineum Therapeutics | 2023-06-26 |
| CTS2190 Phase I /II Clinical Study in Patients (NCT06224387) | CytosinLab Therapeutics Co., Ltd. | 2023-06-26 |
| Safety and Efficacy of PMT Therapy of hPAP (NCT05761899) | Children's Hospital Medical Center, Cincinnati | 2023-06-26 |
| A Study to Compare Two Formulations of LY3209590 in Healthy Participants (NCT05914688) | Eli Lilly and Company | 2023-06-26 |
| Intracoronary Administration of OmniMSC-AMI for Acute ST-segment Elevation Myocardial Infarction Patients (NCT05724576) | Taiwan Bio Therapeutics Inc. | 2023-06-26 |
| Venetoclax in Addition to Sequential Conditioning With Fludarabine / Amsacrine / Ara-C (FLAMSA) + Treosulfan for Allogeneic Blood Stem Cell Transplantation in Patients With MDS, CMML or sAML (NCT05807932) | Heinrich-Heine University, Duesseldorf | 2023-06-26 |
| Study to Assess the Effect of the New HFA-152a Propellant on Mucociliary Clearance (NCT05875025) | Chiesi Farmaceutici S.p.A. | 2023-06-26 |
| Choline Effects - Pre-symptomatic AD (NCT05880849) | Paul E Schulz | 2023-06-26 |
| Study to Determine the Safety and Efficacy of Ribociclib in Combination With Hormone Therapy and Hypofractionated Radiotherapy in Breast Cancer, With Positive Hormone Receptors and Negative HER2 Status, in Newly Diagnosed, Not Immediately Operable Elderly Patient (CALHYS) (NCT05664893) | Centre Antoine Lacassagne | 2023-06-26 |
| A Drug Interaction Study Assess the Effects of ZSP1273 Tablets on the Pharmacokinetics of Warfarin and Midazolam (NCT05942365) | Guangdong Raynovent Biotech Co., Ltd | 2023-06-25 |
| A Study of BL-B01D1 in Patients With Multiple Solid Tumors, Including Recurrent or Metastatic Gynecological Malignancies (NCT05803018) | Sichuan Baili Pharmaceutical Co., Ltd. | 2023-06-25 |
| The ENERGY Study: Evaluation of Safety and Tolerability of INZ-701 in Infants With ENPP1 Deficiency or ABCC6 Deficiency (NCT05734196) | Inozyme Pharma | 2023-06-25 |
| Safety, Tolerability, and Pharmacokinetic Study of QLM3003 in Healthy Adult Subjects (NCT05932888) | Qilu Pharmaceutical Co., Ltd. | 2023-06-25 |
| Bioequivalence Study of Perindopril /Amlodipine/Indapamide 8 mg (10 mg)/2.5 mg/10 mg Tablets in Healthy Volunteers Under Fasting Conditions (NCT05940909) | Pharmtechnology LLC | 2023-06-24 |
| A Study of Efficacy and Safety of Pembrolizumab Plus Enfortumab Vedotin (EV) +/- Investigational Agents in First-Line Metastatic Urothelial Carcinoma (mUC) (MK-3475-04B/KEYMAKER-U04) (NCT05845814) | Merck Sharp & Dohme LLC | 2023-06-23 |
| A Study to Test How Well Different Doses of BI 1815368 Are Tolerated by Healthy Men (NCT05857878) | Boehringer Ingelheim | 2023-06-23 |
| A Study to Assess Drug-Drug Interaction Between ABBV-903 and Midazolam in Adult Healthy Volunteers (NCT05895266) | AbbVie | 2023-06-23 |
| TT-10 (PORT-6) and TT-4 (PORT-7) as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors (NCT04969315) | Portage Biotech | 2023-06-23 |
| A Phase 1 Trial to Investigate the Biological Equivalence of 5 × 10 mg Tablets and 2 × 25 mg Tablets of Daridorexant in Healthy Male and Female Japanese Participants (NCT05877222) | Idorsia Pharmaceuticals Ltd. | 2023-06-23 |
| A Study of Levofloxacin Ocular Implant in Patients Undergoing Routine Bilateral Cataract Surgery (NCT05441930) | PolyActiva Pty Ltd | 2023-06-23 |
| Randomized Clinical Trial in Parkinson's Disease Patients Using Pluripotent Adipose Stem Cells (PASCs) (NCT06141317) | ClusterXStem-Costa Rica | 2023-06-23 |
| CTH120 First-in-Human Study: Single and Multiple Ascending Doses and Potential Food Interaction (NCT06480968) | Connecta Therapeutics, S.L. | 2023-06-23 |
| Cisplatin (CIS) Administered As Dry Powder for Inhalation (DPI) in Patients with Stage IV Non-Small Cell Lung Cancer (NCT06896890) | Inhatarget Therapeutics | 2023-06-23 |
| A Study to Learn About the Safety and Immune Activity of RSVpreF in Children 2 to <18 Years of Age (NCT05900154) | Pfizer | 2023-06-22 |
| [18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET (NCT05703685) | National Institute of Mental Health (NIMH) | 2023-06-22 |
| The Safety and Efficacy of Q-1802 Combined With XELOX in Gastrointestinal Tumors (NCT05964543) | QureBio Ltd. | 2023-06-21 |
| Evaluation of the Effect of Rifampin and Rabeprazole on the Pharmacokinetics of Camlipixant (NCT05899829) | Bellus Health Inc. - a GSK company | 2023-06-21 |
| Magrolimab in Combination With Cytotoxic Chemotherapy in Advanced Urothelial Carcinoma (NCT05738161) | Insel Gruppe AG, University Hospital Bern | 2023-06-21 |
| ACT-TIL and ANV419 for Advanced Melanoma. (NCT05869539) | University Hospital, Basel, Switzerland | 2023-06-21 |
| A Safety And Efficacy Study Of HLA-G- Targeted CAR-T Cells IVS-3001 In Subjects With Previously Treated Advanced HLA-G-Positive Solid Tumors (NCT05672459) | M.D. Anderson Cancer Center | 2023-06-21 |
| Head-to-head Study of 68Ga-MGS5 Versus 68Ga-DOTATATE PET/CT in Patients With Medullary Thyroid Carcinoma (NCT06520319) | First Affiliated Hospital of Fujian Medical University | 2023-06-21 |
| Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration (NCT06087458) | Perceive Biotherapeutics, Inc. | 2023-06-21 |
| A Single-arm, Open-label, Clinical Trial of Surufatinib/Serplulimab/Platinum/Etoposide in Neuroendocrine Carcinoma. (NCT05747729) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2023-06-21 |
| Stereotactic Body Radiotherapy Combined With Cadonilimab for Advanced Refractory Malignant Solid Tumors (NCT05915481) | Peking University Third Hospital | 2023-06-21 |
| A PK Study of IkT-148009 in Older and Elderly Healthy Subjects (NCT06644326) | ABLi Therapeutics, Inc. | 2023-06-21 |
| A Clinical Study to Learn if SEP-363856 Has Physical Dependence in Adults With Schizophrenia (NCT05848700) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2023-06-21 |
| Evaluation of Safety, Rate and Extent of Absorption of Psilocin Mucate (NCT06035900) | Lobe Sciences Ltd. | 2023-06-21 |
| Safety and Drug Absorption of Orally Administered Oleylphosphocholine (OlPC) in Healthy Adults (NCT06124144) | University Hospital Tuebingen | 2023-06-21 |
| A Food Effect Study of LP-168 Tablets in Healthy Subjects (NCT05917964) | Guangzhou Lupeng Pharmaceutical Company LTD. | 2023-06-21 |
| A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib as a Single Agent or in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation (NCT05789082) | Hoffmann-La Roche | 2023-06-20 |
| Study of MHB088C for Patients With Advanced Solid Malignant Tumors (NCT07102004) | Qilu Pharmaceutical Co., Ltd. | 2023-06-20 |
| A Phase I SAD/MAD and Liver Effect Study of Vitalangio in Venous Thromboembolism Patients . (NCT07618351) | Peking University First Hospital | 2023-06-20 |
| Effect of Preoperative Oral Ibuprofen on Anesthetic Efficacy of Inferior Alveolar Nerve Block With Supplemental Buccal and Lingual Infiltrations Using Articaine in Mandibular Molar Teeth With Irreversible Pulpitis (NCT05927922) | Cairo University | 2023-06-20 |
| Phase 1 Trial in Patients With Human Papillomavirus (HPV)-Associated Cancer (NCT05826275) | Toragen, Inc. | 2023-06-20 |
| A Phase 1/2 Study of CG001419 Tablets in Adult Subjects With Locally Advanced or Metastatic Solid Tumours Harbouring NTRK Gene Abnormalities (NCT07394374) | Cullgen (Shanghai),Inc | 2023-06-20 |
| Use Of Hall Technique In Deciduous Molars Affected By Extensive Caries Lesions (NCT05301439) | University of Nove de Julho | 2023-06-20 |
| First-in-human, Single Ascending Dose Study of CEL383 in Healthy Adult Subjects (NCT05901883) | Celsius Therapeutics, Inc. | 2023-06-20 |
| A Study of BGB-21447, a Bcl-2 Inhibitor, in Mature B-Cell Malignancies (NCT05828589) | BeOne Medicines | 2023-06-20 |
| A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies (NCT05780034) | Accutar Biotechnology Inc | 2023-06-20 |
| Clinical Trial to Compare and Evaluate the Safety and Pharmacokinetic After Oral Administration of CKD-341 and D958 in Healthy Adults (NCT05921435) | Chong Kun Dang Pharmaceutical | 2023-06-20 |
| Omega 3 Oil: Aging-Related Cognitive Decline (NCT05041088) | Neurological Associates of West Los Angeles | 2023-06-20 |
| A SAD Study of ZT002 Injection in Healthy Participants (NCT06423872) | Beijing QL Biopharmaceutical Co.,Ltd | 2023-06-19 |
| A Safety and Pharmacokinetics Study of ZB004 in Healthy Participants (NCT05794516) | Zenas BioPharma (USA), LLC | 2023-06-19 |
| Evaluation of Safety and Immunogenicity of rVSVΔG-SEBOV-GP Vaccine in Adults With Good General Health (NCT05724472) | International AIDS Vaccine Initiative | 2023-06-19 |
| Adoptive Cell Therapy Using Cancer Specific CD8+ Tumor Infiltrating Lymphocytes in Adult Patients With Solid Tumors (NCT05902520) | AgonOx, Inc. | 2023-06-19 |
| JSP191 (briquilimab) in Subjects with LR-MDS (NCT05903274) | Jasper Therapeutics, Inc. | 2023-06-19 |
| The Safety and Tolerability of CLZ-2002 in Patients With Charcot-Marie Tooth Disease. (NCT05947578) | Cellatoz Therapeutics, Inc | 2023-06-19 |
| [14 C] Study on Mass Balance of TY-9591 in Healthy Chinese Subjects (NCT05871905) | TYK Medicines, Inc | 2023-06-19 |
| Pectointercostal Fascial Plane Block (PIFB) Alone Versus PIFB With Rectus Sheath Block (RSB) in Cardiac Surgery (NCT04908449) | Medical College of Wisconsin | 2023-06-19 |
| To Evaluate the Safety and Tolerability of Multiple Doses of GS3-007a Oral Solution in Healthy Subjects. (NCT05921890) | Changchun GeneScience Pharmaceutical Co., Ltd. | 2023-06-19 |
| Study of BC3402 in Combination With Azacitidine in Patients With MDS and CMML (NCT05970822) | Biocity Biopharmaceutics Co., Ltd. | 2023-06-18 |
| Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics of HL1113-R1 and HL1113-R2 in Healthy Adult Volunteers (NCT07598968) | Hanlim Pharm. Co., Ltd. | 2023-06-18 |
| Mass Balance Study of [14C]HLX208 in China Healthy Subjects (NCT05841940) | Shanghai Henlius Biotech | 2023-06-17 |
| A Clinical Trial to Assess Safety and Pharmacokinetics of Fosnetupitant 235 mg and Metabolites in Healthy Volunteers (NCT06840769) | Helsinn Healthcare SA | 2023-06-17 |
| Study of Polyglycan Superparamagnetic Ferric Oxide Injection on Cardiovascular Magnetic Resonance Imaging (NCT05687864) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2023-06-17 |
| Neo-adjuvant Treatment for Squamous Cell Carcinoma Using Direct Tumor Injection With RP1. (NCT05858229) | Sherrif Ibrahim | 2023-06-16 |
| Allogenic Adipose-Derived Mesenchymal Stem Cells for the Treatment of Recurrent Glioblastoma or Recurrent Astrocytoma in Patients Undergoing Craniotomy (NCT05789394) | Mayo Clinic | 2023-06-16 |
| Phase Ib / Regorafenib With Conventional Chemotherapy/Newly Diagnosed Patients/ Multimetastatic Ewing Sarcoma (NCT05830084) | Gustave Roussy, Cancer Campus, Grand Paris | 2023-06-16 |
| The Study of Single Dose Administration of GR2002 Injection in Chinese Health Volunteers (NCT05954611) | Genrix (Shanghai) Biopharmaceutical Co., Ltd. | 2023-06-16 |
| Efficacy of Pyodine Soaked Gelfoam vs Single Topical Application of Clotrimazole in Otomycosis Treatment (NCT06339294) | Rawalpindi Medical College | 2023-06-16 |
| MR Image Synthesis With Low Gadobutrol Dose and AI (NCT06224543) | Subtle Medical | 2023-06-16 |
| To Evaluate Pharmacokinetics of Tisotumab Vedotin in Chinese Subjects With Metastatic or Recurrent Solid Malignancies (NCT05866354) | Zai Lab (Shanghai) Co., Ltd. | 2023-06-16 |
| Imaging Study of [89Zr]DFO-YS5 for Detecting CD46 Positive Malignancy in Multiple Myeloma (NCT05892393) | Robert Flavell, MD, PhD | 2023-06-16 |
| A Study to Investigate Use of Off-the-shelf Natural Killer (NK) Cells (SAR445419) in Relapsed/Refractory Acute Myeloid Leukemia (NCT05712278) | Sanofi | 2023-06-16 |
| Exploring the PK of Different Doses of Naltrexone in Patients With AUD (NCT05919017) | Shenzhen Sciencare Medical Industries Co., Ltd. | 2023-06-16 |
| Safety of Intravenous Apramycin in Adults (NCT05590728) | National Institute of Allergy and Infectious Diseases (NIAID) | 2023-06-16 |
| Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Donor Stem Cell Transplant for Hematologic Malignancies (NCT05443425) | City of Hope Medical Center | 2023-06-16 |
| Bioequivalence Study of Two Formulations of Clopidogrel Film-coated Tablets 75 mg in Healthy Male Subjects Under Fasting Conditions (NCT05934799) | Pharmtechnology LLC | 2023-06-16 |
| A Phase I Study to Investigate the Effect of Hepatic Impairment on the PK, Safety, and Tolerability of AZD2693 (NCT05919069) | AstraZeneca | 2023-06-16 |
| SA55 Injection: a Potential Therapy for the Prevention and Treatment of COVID-19 (NCT06050460) | Sinovac Life Sciences Co., Ltd. | 2023-06-15 |
| Pharmacokinetics of ZSP1273 in Participants With Hepatic Impairment (NCT05856513) | Guangdong Raynovent Biotech Co., Ltd | 2023-06-15 |
| A Study to Learn About How Loss of Liver Function Affects the Blood Levels of the Study Medicine Called PF-07817883. (NCT05884554) | Pfizer | 2023-06-15 |
| Study to Assess Adverse Events and Compare How Crushed, Ground, and Intact Oral Tablets Venetoclax Moves Through the Body of Healthy Female Adult Volunteers (NCT05909553) | AbbVie | 2023-06-15 |
| Study of RO7515629 in Participants With HLA-G Positive Solid Tumors (NCT05769959) | Hoffmann-La Roche | 2023-06-15 |