| Safety and Efficacy Study of Transplantation of Autologous CD34+ Cells Transduced With the G2ARTE Lentiviral Vector Expressing the DCLRE1C cDNA in Artemis (DCLRE1C) Deficient Severe Combined Immunodeficiency Patients (ARTEGENE) (NCT05071222) | Assistance Publique - Hôpitaux de Paris | 2023-07-19 |
| A Study of HB0045 Injection in Patients With Advanced Solid Tumors (NCT06056323) | Shanghai Huaota Biopharmaceutical Co., Ltd. | 2023-07-18 |
| A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML (NCT05735184) | Kura Oncology, Inc. | 2023-07-18 |
| Study to Investigate the Safety, Tolerability, and Pharmacokinetics of GB-0669 in Healthy Adult Participants (NCT07050511) | Generate Biomedicines | 2023-07-18 |
| A Study of LY3437943 in Healthy Participants With a High Body Mass Index (NCT05959096) | Eli Lilly and Company | 2023-07-18 |
| A Study to Evaluate the Pharmacokinetics Similarity of CBP-201 in Healthy Adult Chinese Subjects (NCT05917782) | Connect Biopharm LLC | 2023-07-18 |
| Neoadjuvant ADT with TULSA in the Treatment of Intermediate Risk Prostate Cancer (NCT05917860) | Turku University Hospital | 2023-07-18 |
| Safety, Tolerability Phase Ia Study of XT1061 in Single and Multiple Doses in Healthy Subjects (NCT06280534) | Xi'an Xintong Pharmaceutical Research Co.,Ltd. | 2023-07-18 |
| Trivalent CAR-T Cell in Acute B-Lineage Leukemia (TRICAR-ALL) (NCT05010564) | Baylor College of Medicine | 2023-07-18 |
| A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of TNX-1500 in Healthy Subjects (NCT07473752) | Tonix Pharmaceuticals, Inc. | 2023-07-18 |
| Phase 1a Study in Healthy Participants (NCT05953506) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2023-07-17 |
| CAR-T Cells in Systemic B Cell Mediated Autoimmune Disease (NCT06347718) | Miltenyi Biomedicine GmbH | 2023-07-17 |
| Two Fraction Prostate SBRT With DIL SIB (NCT05864196) | NYU Langone Health | 2023-07-17 |
| Study Transplanting Bone Marrow Cells Into Salivary Glands to Treat Dry Mouth Caused by Radiation Therapy (NCT05820711) | University of Wisconsin, Madison | 2023-07-17 |
| A Study to Test How Kidney Problems Influence the Blood Concentrations of Efgartigimod (NCT05927415) | argenx | 2023-07-17 |
| Safety, Tolerability, PK and PD Study of AD-214 Administered to Healthy Volunteers and Patients With Interstitial Lung Disease or Chronic Kidney Disease (NCT05914909) | AdAlta Limited | 2023-07-17 |
| A Study of PEP07 (Checkpoint Kinase 1 Inhibitor) in Patients With Advanced Cancer (NCT05659732) | PharmaEngine | 2023-07-17 |
| Amivantamab With Tyrosine Kinase Inhibitors (TKI) for Advanced NSCLC With ALK, ROS1, or RET Alterations (NCT05845671) | University of Colorado, Denver | 2023-07-17 |
| CD70-targeted CAR-NKT Cells(CGC729) Therapy in the Renal Cell Carcinoma (NCT06182735) | Fudan University | 2023-07-17 |
| Patient-Customized Bioprinting Technology for Practical Regeneration of the Respiratory Tract (Trachea) (NCT06051747) | Ja Seong Bae, MD, phD | 2023-07-17 |
| Extension Safety and Immunogenicity Study of GPNV-001 (NCT05982314) | GPN Vaccines | 2023-07-17 |
| Phase I Trial Testing the Safety and Tolerability of Chemoradiation Followed by Chemotherapy + Dostarlimab for Stage IIIC, Node Positive, Endometrial Cancer (NCT05819892) | M.D. Anderson Cancer Center | 2023-07-17 |
| A Study to Evaluate the Effects of Single and Multiple Doses of Hemay005 Tablets in Health Caucasian Adult Volunteers (NCT05941247) | Ganzhou Hemay Pharmaceutical Co., Ltd | 2023-07-17 |
| A Study of Bio-008 in Subjects With Advanced or Metastatic Solid Tumours (NCT06027346) | Shijiazhuang Yiling Pharmaceutical Co. Ltd | 2023-07-17 |
| A Study to Evaluate Safety and Immunogenicity of APV006 in Healthy Adults (NCT05952596) | LG Chem | 2023-07-17 |
| Substance Balance Trial of Methoxyethyl Etomidate Hydrochloride (NCT06822114) | Ahon Pharmaceutical Co., Ltd. | 2023-07-17 |
| A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-386(5) 80/20/10mg (NCT05698043) | Chong Kun Dang Pharmaceutical | 2023-07-17 |
| CD70 Targeted CAR-T Cells in CD70 Positive Advanced/Metastatic Solid Tumors (NCT05947487) | Chinese PLA General Hospital | 2023-07-15 |
| BCMA-GPRC5D CAR-T Therapy in Relapsed or Refractory Multiple Myeloma (NCT06644443) | Shenzhen University General Hospital | 2023-07-15 |
| CD70 Targeted CAR-T Cells in CD70 Positive Relapsed/Refractory Lymphoma (NCT05948033) | Chinese PLA General Hospital | 2023-07-15 |
| The Efface of Ketamine vs. Lidocaine in the Management of Pain After Laparoscopic Cholecystectomy (NCT07248384) | Liaquat National Hospital & Medical College | 2023-07-15 |
| H7HLAII DNA Influenza Vaccine (NCT06046092) | Oslo University Hospital | 2023-07-15 |
| A Study to Evaluate the Pharmacokinetics and Safety Between Single Administration of "BR6002" and Coadministration of "BR6002A" and "BR6002B" Under Fasting Conditions in Healthy Adult Volunteers (NCT05959486) | Boryung Pharmaceutical Co., Ltd | 2023-07-14 |
| Optimizing lymphoDepletion to Improve Outcomes In Patients Receiving Cell Therapy With Yescarta (NCT05950802) | University Health Network, Toronto | 2023-07-14 |
| Dose-Escalation Study of Cabozantinib in Combination With Lutetium-177 (177Lu)-PSMA-617 in Patients With Metastatic Castration-Resistant Prostate Cancer (NCT05613894) | University of Utah | 2023-07-14 |
| Adult Subjects With Elevated Low-Density Lipoprotein-Cholesterol to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects (NCT05905068) | Ikaria Bioscience Pty Ltd | 2023-07-14 |
| LS301-IT in Partial Mastectomy and Sentinel Lymph Node Biopsy (SLNB) for DCIS or Stage I-II Primary Invasive Breast Cancer (NCT05900986) | Integro Theranostics | 2023-07-14 |
| Evaluate the Pharmacokinetics and Safety Between the Treatment of CKD-383 and Treatment of CKD-501, D745, D150, and D029 (NCT05897216) | Chong Kun Dang Pharmaceutical | 2023-07-14 |
| A Study to Investigate Safety and Clinical Activity of Belantamab Mafodotin in Combination With Lenalidomide, Dexamethasone and Nirogacestat in Patients With Transplant Ineligible Newly Diagnosed Multiple Myeloma (NCT05573802) | Hellenic Society of Hematology | 2023-07-14 |
| Safety of AM-928 Infusion in Advanced Solid Tumors (NCT05687682) | AcadeMab Biomedical Inc. | 2023-07-14 |
| Phase 1 Study Evaluating BA3182 in Patients With Advanced Adenocarcinoma. (NCT05808634) | BioAtla, Inc. | 2023-07-14 |
| A Drug-Drug Interaction Study Between XW003 and Metformin, Warfarin, Rosuvastatin or Digoxin (NCT06335134) | Hangzhou Sciwind Biosciences Co., Ltd. | 2023-07-14 |
| A Phase IB Study to Determine the Safety and Tolerability of Canakinumab and Tislelizumab in Combination With Nab-Paclitaxel and Gemcitabine in the Neo-adjuvant Treatment of Patients With Pancreatic Cancer (NCT05984602) | NYU Langone Health | 2023-07-14 |
| HTL0039732 in Participants With Advanced Solid Tumours (NCT05944237) | Cancer Research UK | 2023-07-13 |
| A Phase 1, Parallel, Single-Dose, Open-Label, Single-Period Study of LY3502970 in Participants With Normal Renal Function and Participants With Renal Impairment. (NCT05936138) | Eli Lilly and Company | 2023-07-13 |
| Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of LP-98 Injection in Healthy Subjects (NCT05933824) | Shanxi Kangbao Biological Product Co., Ltd. | 2023-07-13 |
| Spironolactone in Alcohol Use Disorder (SAUD) (NCT05807139) | National Institute on Drug Abuse (NIDA) | 2023-07-13 |
| AK112 and AK104 With or Without Chemotherapy in Advanced Non-small Cell Lung Cancer (NCT05904379) | Akeso | 2023-07-13 |
| IN10018 Combination Therapy in Advanced EGFR Mutation-positive NSCLC (NCT05994131) | InxMed (Shanghai) Co., Ltd. | 2023-07-13 |
| A Study in Healthy Men to Test How Well Different Doses of BI 1839100 Are Tolerated (1490-0003) (NCT05934955) | Boehringer Ingelheim | 2023-07-13 |
| A Study of LY3437943 in Participants With Impaired and Normal Liver Function (NCT05916560) | Eli Lilly and Company | 2023-07-13 |
| Safety and Feasibility Study of the CELLSPAN Esophageal Implant (CEI) in Patients Requiring Short Segment Esophageal Replacement (NCT05877300) | Harvard Apparatus Regenerative Technology, Inc. | 2023-07-13 |
| A Study to Evaluate the Pharmacokinetics and Safety Between Single Administration of "BR6002" and Coadministration of "BR6002A" and "BR6002B" Under Fed Conditions in Healthy Adult Volunteers (NCT05959499) | Boryung Pharmaceutical Co., Ltd | 2023-07-13 |
| Clinical Trial With Adipose Tissue Stem Cells on Biological Matrix for the Treatment of Venous Ulcer of the Lower Limbs (NCT05962931) | Andalusian Network for Design and Translation of Advanced Therapies | 2023-07-12 |
| Phase 1b of Lurbinectedin in Combination With Weekly Paclitaxel and Bevacizumab in Platinum-resistant Ovarian Cancer (NCT05636111) | M.D. Anderson Cancer Center | 2023-07-12 |
| A Study in Elderly Chinese Subjects With Underlying Diseases (NCT06093308) | Shanghai Vinnerna Biosciences Co., Ltd. | 2023-07-12 |
| Pharmacokinetics in Oral and Intranasal Formulations of Zolmitriptan. (NCT06074016) | Parc de Salut Mar | 2023-07-12 |
| Safety, Tolerability and Pharmacokinetics of LNK01004 Ointment in Adults With Atopic Dermatitis. (NCT06553287) | Lynk Pharmaceuticals Co., Ltd | 2023-07-12 |
| Pharmacokinetic Study in Healthy Lactating Women Exposed to Ibrexafungerp (NCT06954493) | Scynexis, Inc. | 2023-07-12 |
| UMIT-1 Trial Favipiravir & Ribavirin for the Treatment of CCHF (NCT05940545) | Liverpool School of Tropical Medicine | 2023-07-12 |
| Evaluation of TLL-018 Extended and Immediate Release Formulation for Bioequivalence Testing in Healthy Chinese Subjects (NCT05945810) | Hangzhou Highlightll Pharmaceutical Co., Ltd | 2023-07-12 |
| A Study to Assess the Effect of Multiple Doses of Itraconazole, Gemfibrozil, or Carbamazepine on BMS-986278 in Healthy Participants (NCT05932303) | Bristol-Myers Squibb | 2023-07-12 |
| PAI-1, tPA, TFPI and HEECs in Uterine Hemostasis (NCT05862805) | Oregon Health and Science University | 2023-07-12 |
| A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation (NCT05877599) | AstraZeneca | 2023-07-12 |
| Phase I Clinical Trials Investigating the Potential Efficacy of Axitinib in Patients With a BRCA 1/2 Mutations (NCT05904730) | Lynkcell Europe | 2023-07-11 |
| Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors (NCT05858736) | OncoC4, Inc. | 2023-07-11 |
| Bioavailability and Safety Study Comparing Two Dose Levels of AMZ001 and One Dose Level of Diclofenac Sodium 1% Gel in Healthy Participants (NCT05968482) | Amzell | 2023-07-11 |
| A SAD/MAD Study to Evaluate the Safety, Tolerability, PK of MT200605 in Healthy Subjects (NCT05948774) | Shaanxi Micot Pharmaceutical Technology Co., Ltd. | 2023-07-11 |
| Study to Assess Adverse Events and Compare How Oral Ubrogepant and Oral Atogepant Moves Through the Body of Healthy Female Adult Volunteers (NCT05892757) | AbbVie | 2023-07-11 |
| A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer (NCT05710848) | SURGE Therapeutics | 2023-07-11 |
| A Study to Evaluate the Efficacy and Safety of CT041 After Adjuvant Chemotherapy for Pancreatic Cancer (NCT05911217) | CARsgen Therapeutics Co., Ltd. | 2023-07-11 |
| Study of AZD5863 in Adult Participants With Advanced or Metastatic Solid Tumors (NCT06005493) | AstraZeneca | 2023-07-11 |
| Safety and Tolerance of Increased Doses of SHR-2106 Injection in Healthy Subjects (NCT05948059) | Guangdong Hengrui Pharmaceutical Co., Ltd | 2023-07-11 |
| A Study of Participants With Chronic Kidney Disease Previously Treated With REACT (NCT05694169) | Prokidney | 2023-07-11 |
| Long-Term Follow-Up Study of HIV-1 Infected Adults Who Received EBT-101 (NCT05143307) | Excision BioTherapeutics | 2023-07-11 |
| Toxicity and Efficacy Evaluation of Topical Minoxidil in Acne Vulgaris (NCT06108193) | Chang Gung Memorial Hospital | 2023-07-11 |
| A Study for Multiple Tablet Forms of The Study Medicine (PF-07220060) in Healthy Adults (NCT05923411) | Pfizer | 2023-07-11 |
| A TQTc Study for Omaveloxolone (NCT05927649) | Biogen | 2023-07-11 |
| A Study of GDX012 in Adults With Relapsed or Refractory Acute Myeloid Leukemia (NCT05886491) | Takeda | 2023-07-11 |
| Study of XH-S003 in Healthy Volunteers (NCT06272747) | S-INFINITY Pharmaceuticals Co., Ltd | 2023-07-10 |
| A Study to Evealuate Safety and Immunogenicity of TI-0010 SARS-CoV-2 Vaccine in Healthy Adults (NCT06205524) | National Drug Clinical Trial Institute of the Second Affiliated Hospital of Bengbu Medical College | 2023-07-10 |
| Taurine Eye Drops May Prevent the Progression of Cataract (NCT06639711) | University Of Anbar | 2023-07-10 |
| Drug-durg Interaction of ZSP1273 With Digoxin, Rosuvastatin,Itraconazole and Probenecid (NCT05954624) | Guangdong Raynovent Biotech Co., Ltd | 2023-07-10 |
| Study of Treatment for HPV16+ ASC-US or LSIL (NCT03913117) | University of Alabama at Birmingham | 2023-07-10 |
| A Study to Compare Zavegepant Concentration Using Samples Collected From the Vein Versus Patient-Centric Microsampling (NCT05948085) | Pfizer | 2023-07-10 |
| Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP) (NCT05552755) | Recursion Pharmaceuticals Inc. | 2023-07-10 |
| Deep Brain Therapy With Low-intensity Ultrasound for Generalized Chronic Pain (NCT05674903) | University of Utah | 2023-07-10 |
| A Study to Assess the Experimental Malaria Vaccines RH5.2-VLP and R21 (NCT05357560) | University of Oxford | 2023-07-10 |
| A Phase 1/2 Study of D3S-002 as Monotherapy or Combination Therapy in Adult Subjects With Advanced Solid Tumors With MAPK Pathway Mutations (NCT05886920) | D3 Bio (Wuxi) Co., Ltd | 2023-07-10 |
| A Study of TQB3454 Tablets in Patients With Blood Tumors (NCT06218771) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2023-07-10 |
| First-in-human Study of OT-A201 in Patients With Selected Hematological Malignancies and Solid Tumors (NCT05828459) | Onward Therapeutics | 2023-07-10 |
| A Study of mRNA-1018 Pandemic Influenza Candidate Vaccines in Healthy Adults (NCT05972174) | ModernaTX, Inc. | 2023-07-10 |
| To Evaluate the Safety and Efficacy of GS1191-0445 Injection in the Treatment of Severe Hemophilia A (NCT07548411) | Gritgen Therapeutics Co., Ltd. | 2023-07-10 |
| Single Dose Study of [14C]-IDV184001AN ([14C]-IDV184001) in Healthy Adult Male Participants (NCT05974046) | Indivior Inc. | 2023-07-10 |
| A Clinical Trial to Compare and Evaluate the Safety and Pharmacokinetics of D745, D759, and D150 (NCT05928637) | Chong Kun Dang Pharmaceutical | 2023-07-10 |
| A Study to Evaluate the Bioavailability, Food Effect and Pharmacokinetics of Deuremidevir Hydrobromide for Suspension (NCT05932459) | Vigonvita Life Sciences | 2023-07-09 |
| A Study to Evaluate the Effect of a Single Oral Dose of ZX-7101A on the QTc Interval in Healthy Subjects (NCT05955027) | Nanjing Zenshine Pharmaceuticals | 2023-07-08 |
| Mass Balance Study of [14C]JAB-21822 (NCT05920941) | Allist Pharmaceuticals, Inc. | 2023-07-08 |
| Metastatic Nasopharyngeal Carcinoma (NCT06886347) | Chen Xiaozhong | 2023-07-07 |
| Dolutegravir Pharmacokinetics Among HIV/TB Coinfected Children Receiving Standard and High-dose Rifampicin (NCT05069688) | Brigham and Women's Hospital | 2023-07-07 |