| A First In Human (FIH) Study of IBI356 in Healthy Participants and in Atopic Dermatitis Patients (NCT06193434) | Innovent Biologics (Suzhou) Co. Ltd. | 2024-01-05 |
| FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors (NCT06241456) | Fate Therapeutics | 2024-01-05 |
| Study of AGN-151586 in Japanese Participants With Moderate to Severe Glabellar Lines (NCT06151561) | AbbVie | 2024-01-05 |
| Topical Statin Eye Drop in the Management of the Dry Eye (NCT06208384) | Shahid Beheshti University of Medical Sciences | 2024-01-04 |
| PrProfile: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ION717 (NCT06153966) | Ionis Pharmaceuticals, Inc. | 2024-01-04 |
| Safety and Effect of Intravitreal Injection of a Derivative of Nucleoside Reverse Transcriptase Inhibitor in Subjects with Diabetic Macular Edema (NCT05699759) | Michelle Abou-Jaoude | 2024-01-04 |
| PK Effects of SHR4640 on Repaglinide and Midazolam, and the Impact of SHR4640 on QT Interval (NCT06196580) | Jiangsu HengRui Medicine Co., Ltd. | 2024-01-04 |
| A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-348(6) (NCT06112678) | Chong Kun Dang Pharmaceutical | 2024-01-04 |
| A Phase 1 Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics, of VX-993 (NCT06226454) | Vertex Pharmaceuticals Incorporated | 2024-01-04 |
| A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation (NCT06179160) | Incyte Corporation | 2024-01-04 |
| Bioequivalence Study to Compare Empagliflozin/ Metformin HCl 12.5mg/1000mg Film-coated Tablets (NCT06450262) | Humanis Saglık Anonim Sirketi | 2024-01-04 |
| Comparative Evaluation of Bromelain-Quercetin Gel With Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing In Stage I /II and Grade B Periodontitis - Randomized Control Clinical Trail (NCT06775392) | Krishnadevaraya College of Dental Sciences & Hospital | 2024-01-04 |
| A Phase 1b Clinical Trial of 13-valent Pneumococcal Polysaccharide Conjugate Vaccine (NCT06183216) | Sinovac Research and Development Co., Ltd. | 2024-01-04 |
| Study to Assess the Safety, Tolerability, and Blood Concentration of PMC-309 (NCT05957081) | PharmAbcine | 2024-01-03 |
| Dose-Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics From Single Dose of Intramuscular (IM) and Subcutaneous (SC) Donepezil (GB-5001) Injections Versus Donepezil Oral Tablet (Aricept®) in Healthy Male Volunteers (NCT06127368) | G2GBio, Inc. | 2024-01-03 |
| A Phase 1 Study to Evaluate TGI-6 in Subjects With Locally Advanced/Metastatic Solid Tumors (NCT06374173) | Hefei TG ImmunoPharma Co., Ltd. | 2024-01-03 |
| A Phase I Study to Assess the Safety and Tolerability of BL0006 for Patients With Advanced Solid Tumours (NCT06247657) | Shanghai Best-Link Bioscience, LLC | 2024-01-03 |
| A Study of Carbon-14-Labeled [14C]-LY3549492 in Healthy Participants (NCT06194500) | Eli Lilly and Company | 2024-01-03 |
| PRO1107 in Patients With Advanced Solid Tumors (NCT06171789) | Genmab | 2024-01-03 |
| A Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Oral Dose Escalation of GS1-144 Tablets and the Effects of Food on the Pharmacokinetics of GS1-144 in a Chinese Population (NCT06385158) | Changchun GeneScience Pharmaceutical Co., Ltd. | 2024-01-03 |
| A Phase 1/2 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMN 351 in Participants With Duchenne Muscular Dystrophy (NCT06280209) | BioMarin Pharmaceutical | 2024-01-03 |
| Effectiveness of Omega-3 Poly Unsaturated Fatty Acids on The Treatment of Gingival Hyperpigmentation (NCT07067515) | Suez Canal University | 2024-01-03 |
| L-Citrulline and Endothelial Function (NCT05722860) | University of Oklahoma | 2024-01-03 |
| The Study of Immunization in People Living With HIV Undergoing an ATI for Elicitation of VRC01-lineage Antibodies (NCT06006546) | National Institute of Allergy and Infectious Diseases (NIAID) | 2024-01-03 |
| Phase 1 Study of Allo-RevCAR01-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies (NCT05949125) | AvenCell Europe GmbH | 2024-01-03 |
| A Phase Ib, Multicenter, Open-Label Study of Multiple-Dose EA5 in Adults With Paroxysmal Nocturnal Hemoglobinuria (PNH) (NCT07256301) | Shanghai Lanyi Therapeutics Co., Ltd. | 2024-01-03 |
| Bioequivalence Study to Compare Dolutegravir 50mg Film-coated Tablets (NCT06450275) | Humanis Saglık Anonim Sirketi | 2024-01-03 |
| Study of TYK-00540 Tablets in Patients With Advanced Solid Tumors (NCT06950086) | TYK Medicines, Inc | 2024-01-02 |
| A Study to Evaluate the Pharmacokinetics, Safety and Immunogenicity of BIIB800 Subcutaneously (SC) Compared to Actemra® in Healthy Male Participants (NCT06262477) | Biogen | 2024-01-02 |
| A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants (NCT06186622) | Eli Lilly and Company | 2024-01-02 |
| Effects of Marijuana on Neuropathic Pain and Spasticity in Spinal Cord Injury Patients (NCT06190470) | Khon Kaen University | 2024-01-02 |
| A Study of TYK-00540 in Adult Patients With Solid Tumors (NCT06246071) | TYK Medicines, Inc | 2024-01-02 |
| Analgesic Effect of Illiohypogastic & Ilioinguinal Nerve Block in TAVR - TF (Prospective Randomized Study) (NCT06362915) | Ain Shams University | 2024-01-02 |
| Safety and Efficacy of Topical Sodium Metabisulfite for the Treatment of Calcinosis in Patients With Systemic Sclerosis (NCT06155578) | Pontificia Universidad Catolica de Chile | 2024-01-02 |
| Mesenchymal Stem Cells for The Treatment of Acute Respiratory Distress Syndrome (ARDS) (NCT04347967) | Meridigen Biotech Co., Ltd. | 2024-01-01 |
| ImmunoTHerapy Adjacent to Cervical CAncer (ITHACA) Study (NCT06095674) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2024-01-01 |
| Addressing Gaps in the Hypertension and Diabetes Care Continuum in Rural Bangladesh: The Dinajpur Study (NCT06258473) | BRAC University | 2024-01-01 |
| Study of OB-002 in Patients With Refractory Metastatic Cancer (NCT05940844) | Orion Biotechnology Polska Sp. z o.o. | 2024-01-01 |
| Semaglutide GLP1 Agonists With Degludec Basal-bolus Insulin in Early Type 1 Diabetes to Basal-bolus (NCT06057077) | Ministry of Health, Saudi Arabia | 2024-01-01 |
| Dual-targeting CLDN18.2 and PD-L1 CAR-T for Patients with CLDN18.2-positive Advanced Solid Tumors (NCT06084286) | Sichuan University | 2024-01-01 |
| The Glucagonotropic Effects of Glucose-dependent Insulinotropic Polypeptide and Alanine in Healthy Individuals (NCT06419686) | University Hospital, Gentofte, Copenhagen | 2024-01-01 |
| Use of Cyanoacrylate in Healing and Pain in the Palatal Donor Site of Connective Tissue Grafts (NCT06116539) | Alfonso X El Sabio University | 2024-01-01 |
| Low Rectal Cancer Treated With Total Neoadjuvant Therapy Plus Concurrent Tislelizumab Immunotherapy (NCT07561060) | Fudan University | 2024-01-01 |
| Mass Balance Study of TQB3616 (NCT06149611) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2024-01-01 |
| Diosmin for Treatment of Delayed-onset Muscle Soreness (DOMS) (NCT06125002) | Sergio Marques Borghi | 2024-01-01 |
| Use of Extracellular Vesicles (EV) for Knee Osteoarthrosis (NCT06937528) | University of Jordan | 2024-01-01 |
| Study to Evaluate the Safety of ATR-04 (NCT04731259) | Azitra Inc. | 2024-01-01 |
| A Clinical Study of [177Lu]Lu-XT117 Injection in Patients With Advanced Solid Tumors (NCT06197139) | Xinlu Wang | 2024-01-01 |
| Role of Citicoline in Treatment of Neonates With Hypoxic Ischemic Encephalopathy (NCT06522581) | Armed Forces Hospital, Pakistan | 2024-01-01 |
| Clinical Study of Short-course Radiotherapy Followed by Fruquintinib Plus Sintilimab vs Bevacizumab Plus Capecitabine as First Line Treatment in Advanced mCRC (NCT06195670) | Zhejiang Cancer Hospital | 2024-01-01 |
| Stem Cell Study for Long COVID-19 Neurological Symptoms (NCT06156241) | Charles Cox | 2024-01-01 |
| PLAsticity, Security and Tolerance to Intermittent Hypoxic Conditioning Following Stroke (NCT05210088) | University Hospital, Grenoble | 2024-01-01 |
| Rollover Study From EXG-US-01 (NCT05868499) | Elixirgen Therapeutics, Inc. | 2024-01-01 |
| Efficacy of Injectable Vitamin D Supplementation in Females With Polycystic Ovary Syndrome (NCT06045351) | Aga Khan University | 2024-01-01 |
| Delaying the Onset of Nearsightedness Until Treatment Study (NCT06029530) | Ohio State University | 2024-01-01 |
| Early Phase Human Drug Trial to Investigate DYN101 in Participants 2 to 17 Years With Centronuclear Myopathies (NCT04743557) | Dynacure | 2024-01-01 |
| Safety and Potential Effect of Innovative Cell-based Therapy Using Adipose-derived Stromal Vascular Fraction in Patients With Autoimmune Xerostomia (NCT05857358) | Assistance Publique Hopitaux De Marseille | 2024-01-01 |
| Broadly Neutralizing Antibodies 3BNC117-LS & 10-1074-LS to Prevent Relapse During ATI (NCT05079451) | National Institute of Allergy and Infectious Diseases (NIAID) | 2024-01-01 |
| Gedatolisib in Combination With Darolutamide in Metastatic Castration-Resistant Prostate Cancer (NCT06190899) | Celcuity Inc | 2024-01-01 |
| Novel Cellular Therapy for the Treatment of Pain Associated With Chronic Pancreatitis (NCT05925036) | VA Office of Research and Development | 2024-01-01 |
| Targeting Metastatic Breast Cancers by Alkaline Glucosodiene Molecules Via a Metabolic Pathway Phase I Clinical Trial (NCT05957939) | Ministry of Health, Saudi Arabia | 2024-01-01 |
| Clinical Trial of Roflumilast Added to Standard Chemoimmunotherapy (NCT05796271) | The University of Texas Health Science Center at San Antonio | 2024-01-01 |
| A Clinical Study of [177Lu]Lu-XT117 Injection in Patients With Advanced Solid Tumors (NCT06211647) | Ruimin Wang | 2024-01-01 |
| MAGE-A4-directed TCR-T in the Treatment Amongst Subjects With Advanced Solid Tumors (NCT06170294) | Peking University | 2024-01-01 |
| Safety and Efficacy of HydroLenz for Vitrectomy-Induced Lens Opacities (NCT05592912) | PromiSight, LLC | 2024-01-01 |
| Safety and Immunotherapeutic Activity of Cemiplimab in Participants With HBV on Suppressive Antiviral Therapy (NCT04046107) | National Institute of Allergy and Infectious Diseases (NIAID) | 2024-01-01 |
| Effects of Probiotics on Synaptic Plasticity During the Menstrual Cycle (NCT06213428) | McMaster University | 2024-01-01 |
| Amniotic Membrane for Dacryocystorhinostomy (NCT06226181) | Instituto de Oftalmología Fundación Conde de Valenciana | 2024-01-01 |
| TIL Therapy for Patients With Advanced Solid Tumors (NCT06107894) | NeogenTC | 2024-01-01 |
| Randomized Controlled Trial of Internal Fixation Reconstruction With Stent Screw in the Treatment of Kummell's Disease (NCT06093087) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2024-01-01 |
| A Clinical Trial Evaluating JYP0035 Capsule Monotherapy in Patients With Advanced Solid Tumors (NCT06158477) | Chengdu JOYO pharma Co., Ltd. | 2024-01-01 |
| Bariatric Surgery Combined With GLP-1 Receptor Agonists Study (NCT07336862) | China-Japan Friendship Hospital | 2024-01-01 |
| Hyperbaric Oxygen Therapy for Perianal Fistulizing Crohn's Disease Not Responsive or Intolerant to Conventional Care: HYPNOTIC Pilot Study (NCT06109961) | Ottawa Hospital Research Institute | 2024-01-01 |
| Vitamin B12 and Folinic Acid Supplementation in Mitochondrial DNA Deletion Syndromes (NCT06186154) | University of British Columbia | 2024-01-01 |
| Management Of Patellar Fractures By Craniofacial Mesh Plate Osteosynthesis Augmented by Screws (NCT06205914) | Sohag University | 2024-01-01 |
| Study to Evaluate Safety and Activity of TRL1068 in Chronic Rhinosinusitis (NCT05355207) | Trellis Bioscience LLC | 2024-01-01 |
| Rebamipide in Patients With Active Rheumatoid Arthritis (NCT05166304) | October 6 University | 2024-01-01 |
| Risk of Nerve Damage After Administration of Local Anesthesia (NCT06564987) | Cleveland Dental Institute | 2024-01-01 |
| B7-H3 NIR Imaging for Osteosarcoma Surgery (NCT06778603) | Peking University People's Hospital | 2024-01-01 |
| A Bioequivalence Study of Sacubitril/Valsartan Film-coated Tablets Under Fasting Conditions (NCT06193187) | Dr. Reddy's Laboratories (Thailand) Limited | 2024-01-01 |
| HYpofractionated Pelvic Radiotherapy for Advanced Cervical Cancers INeligible for ChemoTherapy (NCT05210270) | University of Santo Tomas Hospital, Philippines | 2024-01-01 |
| Clinical Study to Evaluate Safety and Dosing of CA9hu-1 in Patients With Advanced Solid Tumours (NCT05698238) | Mabpro, a.s. | 2024-01-01 |
| Neuroimmune Mechanisms in Obesity (NCT05553405) | Yale University | 2024-01-01 |
| Docosahexaenoic Acid (DHA) Supplementation in Amblyopia (NCT03402789) | Johns Hopkins University | 2024-01-01 |
| Trazodone on OSA Endotypes (NCT06286189) | Brigham and Women's Hospital | 2024-01-01 |
| A Dose Escalation Study to Estimate MTD, DLTs and Pharmacokinetics After a Single Intracranial Dose of SI-053 as an add-on to the Current Standard of Care, in Adult Patients With Newly Diagnosed GBM (NCT04967690) | Double Bond Pharmaceutical AB | 2024-01-01 |
| Zanubrutinib, Obinutuzumab and Lenalidomide in Newly Diagnosed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (NCT06547944) | Institute of Hematology & Blood Diseases Hospital, China | 2024-01-01 |
| Study of AROSOD-1 in Adult Participants With Amyotrophic Lateral Sclerosis (ALS) (NCT05949294) | Arrowhead Pharmaceuticals | 2024-01-01 |
| Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant Depression (NCT06480201) | Texas A&M University | 2024-01-01 |
| Comparison Between Carbapenems and Noncarbapenem Beta-lactam Antibiotics in Septic Burn Patients (NCT07096310) | Ain Shams University | 2024-01-01 |
| A Clinical Trial of TQB3909 Tablets Combined With TQB3702 Tablets in Patients With Hematologic Malignancy (NCT06211751) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2024-01-01 |
| Cisplatin Plus Temozolomide Compared With Temozolomide in Patients With MGMT Promotor Unmethylated Glioblastoma (NCT06186440) | Zhongnan Hospital | 2024-01-01 |
| 177Lu-HTK03170 in mCRPC With PSMA Positive Disease (NCT05570994) | British Columbia Cancer Agency | 2024-01-01 |
| Efficacy and Safety of MSLN CAR-T in Advanced Malignant Tumors (NCT07399769) | Shenzhen University General Hospital | 2024-01-01 |
| Osimertinib, Cetuximab, and Tucatinib for the Treatment of EGFR-Mutant Stage IV or Recurrent Non-small Lung Cell Cancer (NCT06067776) | Jonathan Riess | 2024-01-01 |
| Ablation in Combination With Lenvatinib and Anti-PD-1 Antibodies (NCT05803928) | Hua Li | 2024-01-01 |
| Safety and Efficacy Study of hAESCs Therapy for aGVHD (NCT06164288) | Shanghai iCELL Biotechnology Co., Ltd, Shanghai, China | 2024-01-01 |
| Connectivity Changes Associated With Ketamine Assisted Psychotherapy for PTSD (NCT06036511) | University of New Mexico | 2023-12-31 |
| Safety and Preliminary Clinical Activity of Itolizumab in ARDS (NCT05978544) | Biotech Pharmaceutical Co., Ltd. | 2023-12-31 |
| The Efficacy and Safety of LMV-12 Combined With Osimertinib in NSCLC (NCT06109558) | Hunan Province Tumor Hospital | 2023-12-31 |